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Number of items: 513.

A

Abazeed, Mohamed E. and Adams, Drew J. and Hurov, Kristen and Tamayo, Pablo and Creighton, Chad J. and Sonkin, Dmitriy and Giacomelli, Andrew O. and Pashtan, Itai and Du, Charles and Fries, Daniel F. and Wong, Kwok-Kin and Mesirov, Jill P. and Loeffler, Jay S. and Schreiber, Stuart L. and Hammerman, Peter S. and Meyerson, Matthew (2013) Integrative radiogenomic profiling of squamous cell lung cancer. Cancer Research, 73 (20). pp. 6289-6298. ISSN 0008-5472.CAN-13-1616

Adamo, Roberto and Proietti, Daniela and Gavini, Massimiliano and Romano, Maria Rosaria and Maclennan, Calman Alexander and Costantino, Paolo and Berti, Francesco (2013) Meningococcal X polysaccharide quantification by high-performance anion-exchange chromatography with pulsed amperometric detection using synthetic N-acetylglucosamine-4-phosphate as standard. Analytical Biochemistry, 44. pp. 259-261.

Alajati, A and Sausgruber, N and Aceto, N and Duss, S and Sarret, S and Voshol, H and Bonenfant, D and Bentires-Alj, M (2013) Mammary Tumor Formation and Metastasis Evoked by a HER2 Splice Variant. CANCER RESEARCH. pp. 5320-5327.

Alderton, WK and Anderson, RJ and Collingwood, SP and Pryde, DC (2013) THERAPEUTIC OPPORTUNITIES IN INFECTIOUS DISEASES HIGHLIGHTS FROM THE SOCIETY OF MEDICINES RESEARCH SYMPOSIUM, HELD ON MARCH 14TH 2013 AT THE NATIONAL HEART & LUNG INSTITUTE, LONDON, UK. DRUGS OF THE FUTURE. pp. 347-354.

Altstein, L and Li, G (2013) Latent Subgroup Analysis of a Randomized Clinical Trial through a Semiparametric Accelerated Failure Time Mixture Model. BIOMETRICS. pp. 52-61.

Anna-Lena, Gessler and Warncke, Max (2013) Master Thesis: Pathogenese und Keimzentrumsreaktion im Typ 1 Diabetes Mausmodell (Pathogenesis and germinal center reaction in the NOD T1D mouse model). University Freiburg.

Antoine, Daniel and Dear, James and Starkey-Lewis, Philip and Platt, Vivien and Coyle, Judy and Masson, Moyra and Thanacoody, Ruben and Gray, Alastair and Moggs, Jonathan and Bateman, Nicholas and Goldring, Christopher and Park, Kevin (2013) Mechanistic biomarkers provide early and sensitive detection of paracetamol-induced acute liver injury at first presentation to hospital. Journal of Hepatology, 58. ISSN 0168-8278

Antony, D and Becker-Heck, A and Zariwala, MA and Schmidts, M and Onoufriadis, A and Forouhan, M and Wilson, R and Taylor-Cox, T and Dewar, A and Jackson, C and Goggin, P and Loges, NT and Olbrich, H and Jaspers, M and Jorissen, M and Leigh, MW and Wolf, WE and Daniels, MLA and Noone, PG and Ferkol, TW and Sagel, SD and Rosenfeld, M and Rutman, A and Dixit, A and O'Callaghan, C and Lucas, JS and Hogg, C and Scambler, PJ and Emes, RD and Chung, EMK and Shoemark, A and Knowles, MR and Omran, H and Mitchison, HM (2013) Mutations in CCDC39 and CCDC40 are the Major Cause of Primary Ciliary Dyskinesia with Axonemal Disorganization and Absent Inner Dynein Arms. Human Mutation. pp. 462-472.

Arias, HR and Fedorov, NB and Benson, LC and Lippiello, PM and Gatto, GJ and Feuerbach, Dominik and Ortells, MC (2013) Functional and Structural Interaction of (-)-Reboxetine with the Human alpha4beta2 Nicotinic Acetylcholine Receptor. Journal of Pharmacology and experimental therapeutics, 344 (3). pp. 113-123. ISSN 112.197905

Arias, HR and Lopez, JJ and Feuerbach, D and Fierro, A and Ortells, MO and Perez, EG (2013) The International Journal of Biochemistry & Cell Biology. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. pp. 2420-2430.

Arias, HR and Ortells, MO and Feuerbach, Dominik (2013) Interaction of (-)-reboxetine with nicotinic acetylcholine receptors in different conformational states. International Journal of biochemistry and cell biology.

Assenberg, Rene and Wan, Paul and Geisse, Sabine and Mayr, Lorenz (2013) Advances in heterologous expression of recombinant proteins. Current opinion in Structural Biology, 23 (3). pp. 393-402. ISSN 0959-440X

Atassi, F and Behme, RJ and Patel, PJ (2013) Mesomorphous versus traces of crystallinity: The itraconazole example. THERMOCHIMICA ACTA. pp. 133-139.

Auclair, JR and Johnson, JL and Liu, Q and Salisbury, JP and Rotunno, MS and Petsko, GA and Ringe, D and Brown, J and Bosco, DA and Agar, JN (2013) Post-translational modification by cysteine protects Cu/Zn-superoxide dismutase from oxidative damage. Biochemistry. pp. 6137-6144.

Auld, D and Lea, W and Davis, MI and Simeonov, A (2013) Literature Search and Review: 3D Cocultures of Multiple Cell Types: What do they do and Where do they Go? Assay and Drug Development Technologies, 11 (8). pp. 457-467.

Auld, D and Lea, W and Davis, MI and Simeonov, A (2013) Literature Search and Review: BLI Coupled with DNA Tetrahedron. Assay and Drug Development Technologies, 11 (3). pp. 139-151. ISSN 1540-658X1557-8127

Auld, D and Lea, W and Davis, MI and Simeonov, A (2013) Literature Search and Review: Better Biosensors for FBDD. Assay and Drug Development Technologies, 11 (5). pp. 289-298. ISSN 1540-658X1557-8127

Auld, D and Lea, W and Davis, MI and Simeonov, A (2013) Literature Search and Review: Detected Through A Quick Glance. Assay and Drug Development Technologies, 11 (1). pp. 1-8. ISSN 1540-658X1557-8127

Auld, DS and Veith, H and Cali, JJ (2013) Bioluminescent assays for cytochrome P450 enzymes. Methods in Molecular Biology. pp. 1-9.

Auld, Douglas and Breault, Lyne and Pandey, Pramod and Ho, Pei-I and Harbinski, Fred and Hill, William (2013) Reporter enzyme inhibitor study to aid assembly of orthogonal reporter gene assays. ACS Chemical Biology, 8 (5). pp. 1009-1017. ISSN 1554-8929

Azzaoui, Kamal and Jacoby, Edgar and Senger, Stefan and Cuadrado Rodríguez, Emiliano and Loza, Mabel and Zdrazil, Barbara and Pinto, Marta and Williams, Antony J and de la Torre, Victor and Mestres, Jordi and Taboureau, Olivier and Rarey, Matthias and Ecker, Gerhard F (2013) Analysis of the scientific competency questions followed by the IMI OpenPHACTS consortium for the development of the semantic web-based molecular information system OPS. Drug Discovery Today, 18 (17-18). pp. 843-852. ISSN 1878-5832

B

Baba, Nobuyasu and Van, VuQuang and Wakahara, Keiko and Weckbecker, Gisbert and Kolbinger, Frank and Heusser, Christoph and Huber, Thomas and Welzenbach, Karl and Sarfati, Marika (2013) CD47 fusion protein targets CD172a+ cells in Crohn's disease and dampens the production of IL-1β and TNF. J Exp Med..

Baeten, Dominique and Baraliakos, Xenofon and Braun, Juergen and Sieper, Joachim and Emery, Paul and Van der Heijde, Desiree and McInnes, Iain and Van Laar, Jacob and Landewé, Robert and Wordsworth, Paul and Wollenhaupt, Jürgen and Kellner, Herbert and Paramarta, Jacqueline and Wei, Jiawei and Brachat, Arndt Holger and Bek, Stephan and Laurent, Didier and Li, Yali and Bertolino, Arthur and Gsteiger, Sandro and Wright, Andrew and Hueber, Wolfgang (2013) Anti-interleukin-17A monoclonal antibody secukinumab in treatment of ankylosing spondylitis: A randomised, double-blind, placebo-controlled trial. The Lancet, 382 (9906). pp. 1705-1713. ISSN 01406736

Balibar, Carl and Mcguire, Dorothy and Dean, Charles (2013) Elongation Factor P is dispensable in Escherichia coli and Pseudomonas aeruginosa. Current Microbiology, 284. ISSN 0343-8651

Ballabeni, A and Zamponi, R and Moore, JK and Helin, K and Kirschner, MW (2013) Geminin deploys multiple mechanisms to regulate Cdt1 before cell division thus ensuring the proper execution of DNA replication. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. E2848-E2853.

Ballard, Sarah and Engeloch, Caroline and Baeschlin, Daniel (2013) Automated compound management evolves to meet the drug discovery demands of the future. Drug Discovery world.

Baltus, Christine and Press, Neil and Coles, Simon and Tizzard, Graham and Spencer, John and Chuckowree, Irina and Day, Iain (2013) Olefin cross-metathesis/Suzuki-Miyaura reactions on 4-vinylphenylboronic acid pinacol ester. Tetrahedron Letters, 54 (10). pp. 1211-1217. ISSN 0040-4039

Bardelli, M and Alleri, L and Angiolini, F and Buricchi, F and Tavarini, S and Sammicheli, C and Nuti, S and Degl'Innocenti, E and Isnardi, I and Fragapane, E and Del, GG and Castellino, F and Galli, G (2013) Ex Vivo Analysis of Human Memory B Lymphocytes Specific for A and B Influenza Hemagglutinin by Polychromatic Flow-Cytometry. PLoS One.

Barnes, David and Jain, Monish and Bell, Leslie and Ferreira, Suzie and Cohen, Scott and Chen, Xiao-Hui and Amin, Jakal and Snodgrass, Bradley and Hatsis, Panagiotis (2013) Metabolically Stable tert-Butyl Replacement. ACS Medicinal Chemistry Letters. ISSN 1948-5875

Barteau, Samuel and Heudi, Olivier and Kameni Tcheudji, Jacques and Streckfuss, Judith and Tukulula, Matshawandile and Njoroge, Mathew and Mugumbate, Grace and Little, Susan and Grut, Jiri and Rosenthal, Philip J and Wan, Baojie and Franzblau, Scott G and Chibale, Kelly (2013) Tetrazole-based deoxyamodiaquines: synthesis, ADME/PK profiling and pharmacological evaluation as potential antimalarial and antituberculosis agents. Journal of medicinal chemistry, 21 (17). pp. 4904-4913. ISSN 09680896

Bartels, Christian and Looby, Michael and Sechaud, Romain and Kaiser, Guenther (2013) Determination of the pharmacokinetics of glycopyrronium in the lung using a population pharmacokinetic modeling approach. Britisch Journal of Clinical Pharmacology. ISSN 0306-5251

Basu, A and Bodycombe, NE and Cheah, JH and Price, EV and Liu, K and Schaefer, GI and Ebright, RY and Stewart, ML and Ito, D and Wang, S and Bracha, AL and Liefeld, T and Wawer, M and Gilbert, JC and Wilson, AJ and Stransky, N and Kryukov, GV and Dancik, V and Barretina, J and Garraway, LA and Hon, CSY and Munoz, B and Bittker, JA and Stockwell, BR and Khabele, D and Stern, AM and Clemons, PA and Shamji, AF and Schreiber, SL (2013) An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules. Cell. pp. 1151-1161.

Beck, Valerie and Leighton-Davies, Juliet and Beibel, Martin and Roma, Guglielmo and Oakeley, Edward James and Hamon, Jacques and Barbieri, Samuel and Preuss, Inga and Lasbennes-Eckerlen, Marie-Christine and Sailer, Andreas and Suply, Thomas and Seuwen, Klaus and Parker, Christian and Bassilana, Frederic and Lannoy, Vincent and bernard, Jerome and Hannedouche, Sebastien (2013) The identification of the C3a Receptor (C3AR1) as the target of the VGF derived peptide TLQP-21 in rodent cells. Journal of Biological Chemistry, 288 (38). pp. 27434-27443. ISSN 0021-9258

Beckett, Martin (2013) Book Review: Practical Process Research and Development, second edition by Neal G. Anderson, Elsevier, 2012. Chemistry and Industry, Januar. p. 49.

Beckett, Martin (2013) Book review: Organic Synthesis: State of the Art 2009-2011 by Douglass F Taber, Wiley, 2013. Chemistry and Industry, Septem (Septem). pp. 46-47.

Beckman, David and Schneider, Marilynn and Decristofaro, Marc and Samadfam, Rana and Smith, Susan and Pouliot, Louise (2013) Assessment of a nonsteroidal aromatase inhibitor, letrozole, in juvenile rats. Birth Defects Research, 98 (5). pp. 374-390. ISSN 1542-9741

Beckman, David and Youreneff, Maureen and Butt, Mark (2013) Neurotoxicity assessment of artemether in juvenile rats. Birth Defects Research Part B: Developmental and Reproductive Toxicology, 98 (2). pp. 183-199. ISSN 1542-9741

Beckmann, N and Kaltashov, IA (2013) Delivery of biopharmaceuticals: advanced analytical and biophysical methods Preface. ADVANCED DRUG DELIVERY REVIEWS. 1001-.

Bentz, J and O'Connor, MP and Bednarczyk, D and Coleman, J and Lee, C and Palm, J and Pak, YA and Perloff, ES and Reyner, E and Balimane, P and Brannstrom, M and Chu, X and Funk, C and Guo, A and Hanna, I and Heredi-Szabo, K and Hillgren, K and Li, L and Hollnack-Pusch, E and Jamei, M and Lin, X and Mason, AK and Neuhoff, S and Patel, A and Podila, L and Plise, E and Rajaraman, G and Salphati, L and Sands, E and Taub, ME and Taur, JS and Weitz, D and Wortelboer, HM and Xia, CQ and Xiao, G and Yabut, J and Yamagata, T and Zhang, L and Ellens, H (2013) Variability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision Criteria. DRUG METABOLISM AND DISPOSITION. pp. 1347-1366.

Bereau, T and Kramer, C and Monnard, FW and Nogueira, ES and Ward, TR and Meuwly, M (2013) Scoring Multipole Electrostatics in Condensed-Phase Atomistic Simulations. JOURNAL OF PHYSICAL CHEMISTRY B. pp. 5460-5471.

Betschart, Claudia and Hintermann, Samuel and Behnke, Dirk and Cotesta, Simona and Fendt, Markus and Gee, Christine and Jacobson, Laura and Laue, Grit and Ofner, Silvio and Chaudhari, Vinod and Badiger, Sangamesh and Pandit, Chetan and Wagner, Juergen and Hoyer, Daniel (2013) Identification of a Novel Series of Orexin Receptor Antagonists with a Distinct Effect on Sleep Architecture for the Treatment of Insomnia. Journal of Medicinal Chemistry.

Bian, X and Fu, J and Plaza, A and Herrmann, J and Pistorius, D and Stewart, AF and Zhang, Y and Muller, R (2013) In Vivo Evidence for a Prodrug Activation Mechanism during Colibactin Maturation. ChemBioChem, 14 (10). pp. 1194-1197. ISSN 14394227

Bignon, Alexandre and Gaudin, Françoise and Hémon, Patrice and Tharinger, Hugo and Loetscher, Pius and Peuchmaur, Michel and Berrebi, Dominique and Balabanian, Karl (2013) Pivotal role of Ccr1 in murine lupus nephritis. Journal of Immunology.

Billedeau, RJ and Klein, KR and Kaplan, D and Lou, Y (2013) A New Pyrrole Synthesis via Silver(I)-Catalyzed Cycloaddition of Vinylogous Diazoester and Nitrile. ORGANIC LETTERS. pp. 1421-1423.

Billich, Andreas and Baumruker, Thomas and Beerli, Christian and Bigaud, Marc and Bruns, Christian and Calzascia, Thomas and Isken, Andrea and Kinzel, Bernd and Loetscher, Erika and Metzler, Barbara and Mueller, Matthias and Nuesslein-Hildesheim, Barbara and Kleylein-Sohn, Bernadette (2013) Partial deficiency of sphingosine-1-phosphate lyase confers protection in experimental autoimmune encephalomyelitis. PLOS ONE, 8 (3). e59630. ISSN 1932-6203

Billich, Andreas and Beerli, Christian and Bruns, Christian and Loetscher, Erika (2013) Cellular assay for the characterization of sphingosine-1-phosphate lyase inhibitors. Analytical Biochemistry, 434 (2). pp. 247-253. ISSN 0003-2697

Biukovic, Goran and Basak, Sandip and Manimekalai, Malathy Sony Subramanian and Rishikeshan, Sankaranarayanana and Roessle, Manfred and Dick, Thomas and Rao, Srinivasa and Hunke, Cornelia and Gruber, Gerhard (2013) Variations of subunit Varepsilon of the Mycobacterium tuberculosis F-1Fo ATP Synthase and Novel Model for Mechanism of Action of the Tuberculosis Drug TMC207. Antimicrobial Agents and Chemotherapy, 57 (1). pp. 168-176. ISSN 0066-4804

Blache, U and Silvan, U and Plodinec, M and Suetterlin, R and Jakob, R and Klebba, I and Bentires-Alj, M and Aebi, U and Schoenenberger, CA (2013) A Tumorigenic Actin Mutant Alters Fibroblast Morphology and Multicellular Assembly Properties. CYTOSKELETON. pp. 635-650.

Bobardt, M and Hopkins, S and Baugh, J and Chatterji, U and Hernandez, F and Hiscott, J and Sluder, A and Lin, K and Gallay, PA (2013) HCV NS5A and IRF9 compete for CypA binding. JOURNAL OF HEPATOLOGY. pp. 16-23.

Bolton, SA and Sutton, JC and Anumula, R and Bisacchi, GS and Jacobson, B and Slusarchyk, WA and Treuner, UD and Wu, SC and Zhao, G and Pi, Z and Sheriff, S and Smirk, RA and Bisaha, S and Cheney, DL and Wei, A and Schumacher, WA and Hartl, KS and Liu, E and Zahler, R and Seiler, SM (2013) Discovery of nonbenzamidine factor VIla inhibitors using a biaryl acid scaffold. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. pp. 5239-5243.

Bouchez, Laure and Ruffner, Heinz and Spanka, Carsten and Patoor, Maude (2013) Synthesis of a Series of Promising Isobenzofurans for the Reduction of Acute Mucositis Risk after Chemo- and Radiotherapy. Synlett- special edition.

Boulton, C and David, OJ and Meiser, K and Schmouder, R (2013) Tolerability and pulmonary pharmacodynamic effects during treatment initiation of once-daily oral fingolimod in subjects with moderate asthma. Clinical Pharmacology in Drug Development. pp. 2-10.

Bowman, SK and Simon, MD and Deaton, AM and Tolstorukov, M and Borowsky, ML and Kingston, RE (2013) Multiplexed Illumina sequencing libraries from picogram quantities of DNA. BMC Genomics.

Brauchle, Michael and Yao, Zhiping and Arora, Rishi and Clay, Ieuan and Inverardi, Bruno and Gerrits, Bertran and Voshol, Johannes and Bauer, Andreas and Schuebeler, Dirk and Bouwmeester, Antonius and Ruffner, Heinz and Thigale, Sachin (2013) A systematic comparison of enzymatic activity and protein interaction analysis of the KDM3 histone demethylase subfamily. PLOS ONE, 8 (4). e60549. ISSN 1932-6203

Breckner, Anke and Gerwin, Nicole and Richter, Jens and Rausch, Martin and Marcellin, David and Ganz, Magdalena (2013) Effect of calstabin1 depletion on calcium transients and energy utilization in FDB muscle fibers and potential treatment opportunities based on RyR1 stabilizers. The Journal of Biological Chemistry, 8 (11). ISSN 1932-6203

Breitenstein, Werner and Cumin, Frederic and Ehrhardt, Claus and Jacoby, Edgar and Lorthiois, Edwige and Ostermann, Nils and Sellner, Holger and Kosaka, Takatoshi and Webb, Randy and Hassiepen, Ulrich and Wagner, Beatrix and Maibaum, Juergen Klaus (2013) Discovery from in silico 3D Pharmacophore Searches of Novel 3(R),4(S)-disubstituted Pyrrolidine Inhibitors of the Human Aspartyl Protease Renin. Journal of Medicinal Chemistry, 56 (6). pp. 2207-2217. ISSN 0022-2623

Bridges, James P. and Ludwig, Marie-Gabrielle and Mueller, Matthias and Kinzel, Bernd and Sato, Atsuyasu and Xu, Yan and Whitsett, Jeffery A. and Ikegami, Machiko (2013) The Orphan G Protein-Coupled Receptor GPR116 Regulates Pulmonary Surfactant Pool Size. American Journal of Respiratory Cell and Molecular Biology. ISSN 1044-1549

Britschgi, Adrian and Bill, Anke and Brinkhaus, Heike and Rothwell, Christopher and Clay, Ieuan and Duss, Stephan and Rebhan, Michael and Raman, Pichai and Guy, Chantale and Wetzel, Kristie and George, Elizabeth and Popa, Oana and Lilley, Sarah and Choudhury, Hedaythul and Gosling, Martin and Wang, Louis and Fitzgerald, Stephanie and Borawski, Jason and Baffoe, Jonathan and Labow, Mark and Gaither, Larry and Bentires-Alj, Mohamed (2013) Inhibition of the 11q13 amplified calcium activated chloride channel ANO1 reduces Head and Neck and Breast cancer growth. PNAS, 110 (11). E1026-E1034. ISSN 0027-8424

Bulliard, Yannick and Jolicoeur, Rose and Windman, Maurice and Rue, Sarah M and Ettenberg, Seth and Knee, Deborah A and Wilson, Nicholas S and Dranoff, Glenn and Brogdon, Jennifer L (2013) Activating Fc γ receptors contribute to the antitumor activities of immunoregulatory receptor-targeting antibodies. The Journal of Experimental Medicine, 210 (9). pp. 1685-1693. ISSN 1540-9538

Burger, Matthew and Han, Wooseok and Lan, Jiong and Nishiguchi, Gisele and Bellamacina, Cornelia and Lindvall, Mika and Atallah, Gordana and Ding, Yu and Mathur, Michelle and Mcbride, Christopher and Mieuli, Elizabeth and Muller, Kristine and Tamez Jr., Victoriano and Zhang, Yanchen and Huh, Kay and Feucht, Paul and Zavorotinskaya, Tatiana and Dai, Yumin and Holash, Jocelyn and Langowski, John and Garcia, Pablo (2013) Structure Guided Optimization, In Vitro Activity and In Vivo Activity of Pan-PIM Kinase Inhibitors. American Chemical Society Medicinal Chemistry Letters, 4 (12). pp. 1193-1197.

Burmester, Gerd and Durez, Patrick and Shestakova, Galina and Genovese, Mark and Schulze-Koops, Hendrik and Li, Yue and Lewitzky, Steven and Koroleva, Irina and Agarwal, Anni and Lee, David and Hueber, Wolfgang (2013) Caspase 8 modulates the polarisome to prevent lung fibrosis in a murine SSC-like disease model. Arthritis and Rheumatism, 65 (Suppl.). S1171. ISSN 00043591

Butendeich, Heike and Pierret, Noelle and Numao, Shin (2013) Evaluation of a liquid dispenser for assay development and enzymology in 1536 well format. Journal of Laboratory Automation, 18 (3). pp. 245-250. ISSN 2211-0682

Byun, M and Ma, CS and Akcay, A and Pedergnana, V and Palendira, U and Myoung, J and Avery, DT and Liu, Y and Abhyankar, A and Lorenzo, L and Schmidt, M and Lim, HK and Cassar, O and Migaud, M and Rozenberg, F and Canpolat, N and Aydogan, G and Fleckenstein, B and Bustamante, J and Picard, C and Gessain, A and Jouanguy, E and Cesarman, E and Olivier, M and Gros, P and Abel, L and Croft, M and Tangye, SG and Casanova, JL (2013) Inherited human OX40 deficiency underlying classic Kaposi sarcoma of childhood. JOURNAL OF EXPERIMENTAL MEDICINE. pp. 1743-1759.

C

Cai, Mi and Yang, Yi (2013) Targeted genome editing tools for disease modeling and gene therapy. Current Gene Therapy.

Cai, Xinming and Xu, Yongyao and Cheung, Atwood and Tomlinson, Ronald and Alcazer-Roman, Abel and Murphy, Leon and Billich, Andreas and Feng, Yan and Zhang, Bailin and Klumpp, Martin and Rondeau, Jean-Michel and Fazal, Aleem and Wilson, Christopher and Myer, Vic and Joberty, Gerard and Bouwmeester, Antonius and Labow, Mark and Finan, Peter and Porter, Jeffrey and Ploegh, Hidde and Baird, Daniel and De Camilli, Pietro and Tallarico, John and Huang, Qian (2013) PIKfyve, a Class III PI Kinase, Is the Target of the Small Molecular IL-12/IL-23 Inhibitor Apilimod and a Player in Toll-like Receptor Signaling. Chemistry & Biology, 20. pp. 912-921.

Callander, Gabrielle E. and Olorunda, Morenike and Monna, Dominique and Schuepbach, Edi and Langenegger, Daniel and Betschart, Claudia and Hintermann, Samuel and Briard, Emmanuelle and Behnke, Dirk and Cotesta, Simona and Fendt, Markus and Laue, Grit and Ofner, Silvio and Gee, Christine and Jacobson, Laura and Hoyer, Daniel (2013) Kinetic properties of 'dual' orexin receptor antagonists at OX1 and Ox2 receptors. Frontiers in Neuroscience, Neuropharmacology., 7. p. 230. ISSN 1662-453X

Casado, P and Rodriguez-Prados, J and Cosulich, SC and Guichard, S and Vanhaesebroeck, B and Joel, S and Cutillas, PR (2013) Kinase-substrate enrichment analysis provides insights into the heterogeneity of signaling pathway activation in leukemia cells. Science Signaling. rs6-.

Castiello, MC and Bosticardo, M and Pala, F and Catucci, M and Chamberlain, N and van Zelm, MC and Driessen, GJ and Pac, M and Bernatowska, E and Scaramuzza, S and Aiuti, A and Sauer, AV and Traggiai, E and Meffre, E and Villa, A and van der Burg, M (2013) Wiskott-Aldrich Syndrome protein deficiency perturbs the homeostasis of B-cell compartment in humans. Autoimmunity.

Catanese, MT and Loureiro, J and Jones, CT and Dorner, M and von, HT and Rice, MC (2013) Different requirements for scavenger receptor class B type I in hepatitis C virus cell-free versus cell-to-cell transmission. Journal of Virology. pp. 8282-8293.

Chakraborty, Abhijit and Van, Linh and Skerjanec, Andrej and Floch, David and Klein, Ulf and Krammer, Gerhard and Sunkara, Gangadhar and Howard, Danny (2013) Pharmacokinetic and pharmacodynamic properties of canakinumab in patients with gouty arthritis. Journal of Clinical Pharmacology, 53 (12). pp. 1240-1251. ISSN 0091-2700

Chan, HCS and Kendrick, J and Neumann, MA and Leusen, FJJ (2013) Towards ab initio screening of co-crystal formation through lattice energy calculations and crystal structure prediction of nicotinamide, isonicotinamide, picolinamide and paracetamol multi-component crystals. CRYSTENGCOMM. pp. 3799-3807.

Chandriani, Sanjay and Skewes-Cox, Peter and Zhong, Weidong and Ganem, Donald and Divers, Thomas J. and Tennant, Bud C. and Van Blaricum, Anita J. and Kistler, Amy (2013) Identification of a previously undescribed divergent virus from the Flaviviridae family in an outbreak of equine serum hepatitis. Proceedings of the National Academy of Sciences USA, 110 (15). E1407-1415. ISSN 0027-8424

Chang, Henry and Ganem, Donald (2013) A unique herpesviral transcriptional program in KSHV-infected lymphatic endothelial cells leads to mTORC1 activation and rapamycin sensitivity. Cell Host & Microbe, 13 (4). pp. 429-440. ISSN 1931-3128

Che, Jianwei and Guo, Zuojun and Li, Bo and Cheng, Li-Tien and Dzubiella, Joachim and McCammon, J. Andrew (2013) Evaluation of Hydration Free Energy by the Level-Set Variational Implicit-Solvent Model with the Coulomb-Field Approximation. Journal of chemical theory and computation. ISSN 1549-9618

Chen, Jinyun and Chung, Franklin and Yang, Guizhi and Pu, Minying and Gao, Hui and Jiang, Wei and Yin, Hong and Capka, Vladimir and Kasibhatla, Shailaja and Laffitte, Bryan and Pagliarini, Raymond and Chen, Yaoyu and Zhou, Wenlai (2013) Phosphoglycerate dehydrogenase is dispensable for breast tumor maintenance and growth. Oncotarget, 4 (12). pp. 2502-2511. ISSN 1949-2553

Chen, Y and Li, S (2013) Molecular signatures of chronic myeloid leukemia stem cells. Biomarker Research.

Chen, Yaoyu and Chen, Jinyun and Loo, Alice and Jaeger, Savina and Bagdasarian, Linda and Yu, Jianjun and Chung, Franklin and Korn, Joshua and Ruddy, David and Guo, Ribo and Mclaughlin, Megan and Stegmeier, Frank and Pagliarini, Raymond and Porter, Dale and Zhou, Wenlai (2013) Targeting HSF1 sensitizes cancer cells to HSP90 inhibitor. Oncotarget.

Cheng, CH and Leferovich, J and Zhang, XM and Bedelbaeva, K and Gourevitch, D and Hatcher, CJ and Basson, CT and Heber-Katz, E and Marx, KA (2013) Keratin gene expression profiles after digit amputation in C57BL/6 vs. regenerative MRL mice imply an early regenerative keratinocyte activated-like state. PHYSIOLOGICAL GENOMICS. pp. 409-421.

Cheng, DT and Kim, DK and Cockayne, DA and Belousov, A and Bitter, H and Cho, MH and Duvoix, A and Edwards, LD and Lomas, DA and Miller, BE and Reynaert, N and Tal-Singer, R and Wouters, EFM and Agusti, A and Fabbri, LM and Rames, A and Visvanathan, S and Rennard, SI and Jones, P and Parmar, H and MacNee, W and Wolff, G and Silverman, EK and Mayer, RJ and Pillai, SG (2013) Systemic Soluble Receptor for Advanced Glycation Endproducts Is a Biomarker of Emphysema and Associated with AGER Genetic Variants in Patients with Chronic Obstructive Pulmonary Disease. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. pp. 948-957.

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He, YL and Foteinos, G and Neelakantham, S and Mattapalli, D and Kulmatycki, K and Forst, T and Taylor, A (2013) Differential effects of vildagliptin and glimepiride on glucose fluctuations in patients with type 2 diabetes mellitus assessed using continuous glucose monitoring. DIABETES OBESITY & METABOLISM. pp. 1111-1119.

He, Yan-Ling and Zhang, Yiming and Yan, Jing-He and Zhou, Wei and Komjathy, Steven and Taylor, Ann (2013) High-quality triplicate electrocardiogram monitoring in a first-in-man study: potential for early detection of drug-induced QT prolongation. INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS, 51 (12). pp. 948-957. ISSN 0946-1965

Heimbach, Tycho and Xia, Binfeng and Lin, Tsu-han and He, Handan (2013) Case studies for practical food effect assessments across BCS/BDDCS class compounds using in silico, in vitro, and preclinical in vivo data. AAPS Journal, 15 (1). pp. 143-158. ISSN 1550-7416

Hellman, Maarit and Piirainen, Henni and Jaakola, Veli-Pekka and Permi, Perttu (2013) Bridge over troubled proline: assignment of intrinsically disordered proteins using (HCA)CON(CAN)H and (HCA)N(CA)CO(N)H experiments concomitantly with HNCO and i(HCA)CO(CA)NH. Journal of Biomolecular NMR, 58 (1). pp. 49-60. ISSN 0925-2738

Heudi, Olivier and Maganda, Betty and Cortinovis, Agnes and Picard, Franck and Kretz, Olivier (2013) A fast and reliable reversed phase high performance liquid chromatography method for simultaneous determination of selected anti-retroviral and lumefantrine in human plasma. Journal of Chromatography B, 919/92. pp. 52-60. ISSN 1570-0232

Heudi, Olivier and Van Baar, Ben and Rohde, Morten and Wieling, Jaap and Verhaeghe, Tom and Lüdtke, Silke and De Vries, Ronald and White, Steve and Cobb, Zoe and Timmerman, Philip (2013) Internal standard addition in bioanalysis of dried blood spots: results from the EBF DBS-microsampling consortium. Bioanalysis, 5 (17). pp. 2137-2145. ISSN 1757-6180

Hill, RJ and Lou, Y and Tan, SL (2013) B-Cell Antigen Receptor Signaling in Chronic Lymphocytic Leukemia: Therapeutic Targets and Translational Opportunities. INTERNATIONAL REVIEWS OF IMMUNOLOGY. pp. 377-396.

Hoffman, Gregory and Rahal, Rami and Buxton, Frank and Mcallister, Gregory and Xiang, Xiaoqin and Frias, Elizabeth and Huber, Janina and Lindeman, Alicia and Chen, Dongshu and Bagdasarian, Linda and Romero, Rodrigo and Ramadan, Nadire and Phadke, Tanushree and Haas, Kristy and Jaskelioff, Mariela and Wilson, Boris and Meyer, Matthew and Saenz-Vash, Veronica and Zhai, Huili and Mclaughlin, Margaret and Charles, Roberts and Myer, Vic and Porter, Jeffrey and Keen, Nicholas and Mickanin, Craig and Stegmeier, Frank and Jagani, Zainab (2013) A functional screen of the epigenome identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers. Molecular Cancer Therapeutics, 12 (11). ISSN 15357163

Hoffmaster, Keith and Brouwer, Kim and Keppler, Dietrich and Bow, Daniel and Cheng, Yaofeng and Lai, Yurong and Palm, Johan and Stieger, Bruno and Evers, Raymond (2013) In Vitro Methods to Support Transporter Evaluation in Drug Discovery and Development. Clinical Pharmacology and Experimental Therapeutics.

Holderfield, Matthew and Merritt, Hanne and Chan, John and Wallroth, Marco and Tandeske, Laura and Zhai, Huili and Hardy, Stephen and Hekmat-Nejad, Mohammad and Stuart, Darrin and McCormick, Frank and Nagel, Tobi (2013) RAF Inhibitors Activate the MAPK Pathway by Relieving Inhibitory Autophosphorylation. Cancer Cell, 23 (5). pp. 594-602. ISSN 1535-6108

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Iwata, N and Sekiguchi, M and Hattori, Y and Takahashi, A and Asai, M and Ji, B and Higuchi, M and Staufenbiel, M and Muramatsu, S and Saido, TC (2013) Global brain delivery of neprilysin gene by intravascular administration of AAV vector in mice. Scientific Reports.

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Kramer, Christian and Bereau, Tristan and Spinn, Alexander and Liedl, Klaus R. and Gedeck, Peter and Meuwly, Markus (2013) Deriving Static Atomic Multipoles from the Electrostatic Potential. Journal of Chemical Information and Modeling, 53. pp. 3410-3417.

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Lamacchia, C and Palmer, G and Rodriguez, E and Martin, P and Vigne, S and Seemayer, CA and Talabot-Ayer, D and Towne, JE and Gabay, C (2013) The severity of experimental arthritis is independent of IL-36 receptor signaling - art. no. R38. ARTHRITIS RESEARCH & THERAPY.

Laurent, Didier and Yerby, Brittany and Zhang, Bailin and Chen, Xiao-Hui and Gounarides, John and Gao, Jiaping and Duttaroy, Alokesh (2013) Hepatic glycogen cycling contributes to glucose lowering effects of the glucokinase activator LCZ960. European Journal Of Pharmacology, 715 (1-3). pp. 89-95.

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Lazic, SE and Essioux, L (2013) Improving basic and translational science by accounting for litter-to-litter variation in animal models. BMC Neuroscience.

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Ostermann, Nils and Ruedisser, Simon and Ehrhardt, Claus and Breitenstein, Werner and Marzinzik, Andreas and Jacoby, Edgar and Vangrevelinghe, Eric and Ottl, Johannes and Klumpp, Martin and Mueller-Hartwieg, Constanze and Cumin, Frederic and Hassiepen, Ulrich and Trappe, Joerg and Geisse, Sabine and Gerhartz, Bernd and Richert, Paul and Francotte, Eric and Wagner, Beatrix and Kosaka, Takatoshi and Webb, Randy and Maibaum, Juergen Klaus and Baeschlin, Daniel and Sedrani, Richard (2013) A novel class of oral direct renin inhibitors - highly potent 3,5-disubstituted piperidines bearing a tricyclic P3-P1 unit. Journal of medicinal chemistry, 56 (6). pp. 2196-2206. ISSN 0022-2623

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Pantano, Serafino and Dubost, Valerie and Darribat, Katy and Couttet, Philippe and Grenet, Olivier and Busch, Steven and Moulin, Pierre (2013) Differential expression of dipeptidyl peptidase IV in human versus cynomolgus monkey skin eccrine sweat glands. Journal of Molecular Histology, 44 (6). pp. 733-747. ISSN 1567-2387

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Park, So Young and Mun, Hee-Chang and Eom, Young Sil and Jung, Tae Sik and Hong, Suntaek and Lee, Sihoon and Kim, Chul Hoon (2013) Identification and characterization of D410E, a novel mutation in the loop 3 domain of CaSR, in autosomal dominant hypocalcemia and therapeutic approaches with novel calcilytics, AXT914. Clinical Endocrinology, 78 (5). pp. 687-693. ISSN 0300-0664

Parker, C (2013) Antisense Drug Technology, Principles, Strategies and Applications, 2nd edition. JOURNAL OF BIOMOLECULAR SCREENING. 1-.

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Perez, EG and Ocampo, C and Feuerbach, D and Lopez, JJ and Morelo, GL and Tapia, RA and Arias, HR (2013) Novel 1-(1-benzyl-1H-indol-3-yl)-N,N,N-trimethylmethanaminium iodides are competitive antagonists for the human alpha4beta2 and alpha7 nicotinic acetylcholine receptors. MedChemComm. pp. 1166-1170.

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Pethe, Kevin and Jang, Jichan and Kang, Sunhee and Park, Seijin and Ahn, Sujin and Jiricek, Jan and Jung, Juyoung and Jeon, Hee Kyoung and Cechetto, Jonathan and Christophe, Thierry and Kempf, Marie and Jackson, Mary and Lenaerts, Anne J. and Pham, Ha and Jones, Victoria and Seo, Min Jung and Lee, Saeyeon and Kim, Young and Seo, Mooyoung and Seo, Jeong Jea and Ko, Yoonae and Choi, Inhee and Kim, Ryangyeo and Kim, Seyeon and Lim, SeungBin and Yim, SeungAe and Jiyoun Nam, Jiyoun Nam and Hwankyu Kang, Hwankyu Kang and Chun-Taek Oh, Chun-Taek Oh and Yoojin Cho, Yoojin Cho and Yunhee Jang, Yunhee Jang and Junghwan Kim, Junghwan Kim and Chua, Adeline and Tan, Bee Huat and Nanjundappa, Mahesh Bangalore and Rao, Srinivasa P.S. and Barnes, Whitney and Wintjens, René and Walker, John and Alonso, Sylvie and Kim, Jungjun and Oh, Soohyun and Oh, Taegwon and Han, Sung-Jun and No, Zaesung and Lee, Jinhwa and Brodin, Priscille and Cho, Sang-Nae and Nam, Kiyean and Bifani, Juan Pablo and Kim, Jaeseung (2013) Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis. Nature Medicine, 19 (9). pp. 1157-1160. ISSN 1078-8956

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Pillai, Goonaseelan and Mirza, Fareed and Tadmor, Brigitta and Steimer, Jean-Louis and Davies, Geriant and Denti, Paolo and McIlleron, Helen and Holford, Nicholas H G (2013) Pharmacometrics – Opportunity for Reducing Disease Burden in the Developing World. Clinical Pharmacology and Therapeutics:Pharmacometrics & Systems Pharmacology, 2 (e69).

Pistorius, Dominik and Müller, Rolf (2013) Discovery of the rhizopodin biosynthetic gene cluster in Stigmatella aurantiaca Sg a15 by genome mining. ChemBioChem, 13 (3). pp. 416-426.

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Reilmann, Ralf and Saft, Carsten and Süssmuth, Sigurd and Priller, Joseph and Rosser, Anne and Rickards, Hugh and Schöls, Ludger and Pezous, Nicole and Landwehrmeyer,, Bernhard and Gomez-Mancilla, Baltazar and Rouzade-Dominguez, Marie-Laure and Gasparini, Fabrizio and Johns, Donald (2013) Efficacy, Safety and Tolerability of AFQ056 for the treatment of chorea in patients with Huntington’s disease. Movement DIsorders.

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Reisen, Felix and Zhang, Xian and Gabriel, Daniela and Selzer, Paul (2013) Benchmarking of Multivariate Similarity Measures for High Content Screening Fingerprints in Phenotypic Drug Discovery. Journal of Biomolecular Screening, 18 (10). pp. 1284-1297. ISSN 1087-05711552-454X

Renner, Steffen (2013) Past, Present, and Future of Chemogenomics. Molecular Informatics, 32 (11-12). pp. 877-879. ISSN 1868-1751

Rice, DS (2013) Excitatory superficial dorsal horn interneurons are functionally heterogeneous and required for the full behavioral expression of Pain and Itch. Neuron, 78 (2). pp. 312-324. ISSN 0896-6273

Richie, Daryl and Thompson, Katherine and Studer, Christian and Aust, Thomas and Riedl, Ralph and Estoppey, David and Zabawa, Thomas and Drumm Iii, Joseph and Cotesta, Simona and Eichenberger, Juerg and Schuierer, Sven and Hartmann, Nicole and Movva, Rao and Tallarico, John and Ryder, Neil and Hoepfner, Dominic (2013) Identification and Evaluation of Novel Acetolactate Synthase Inhibitors as Antifungal Agents. Antimicrobial Agents and Chemotherapy, 57 (5). pp. 2272-2280. ISSN 0066-4804

Riddick, DS and Ding, X and Wolf, CR and Porter, TD and Pandey, AV and Zhang, Q and Gu, J and Finn, RD and Ronseaux, S and McLaughlin, LA and Henderson, CJ and Zou, L and Fluck, CE (2013) NADPH-cytochrome P450 oxidoreductase: Roles in physiology, pharmacology, and toxicology. Drug Metabolism and Disposition. pp. 12-23.

Rinaldi, F and Clematide, S and Hafner, S and Schneider, G and Grigonyte, G and Romacker, M and Vachon, T (2013) Using the OntoGene pipeline for the triage task of BioCreative 2012. Database-the Journal of Biological Databases and Curation.

Riniker, Sereina and Fechner, Nikolas and Landrum, Gregory (2013) Heterogeneous Classifier Fusion for Ligand-Based Virtual Screening: Or, How Decision Making by Committee Can Be a Good Thing. Journal of Chemical Information and Modeling, 53. pp. 2829-2836.

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Riniker, Sereina and Landrum, Gregory (2013) Similarity maps - a visualization strategy for molecular fingerprints and machine-learning methods. Journal of Cheminformatics, 5. p. 43.

Ritter Iii, Robert and Senchyna, Michelle and Srinivasan, Sruthi and Heynen, Miriam L. and Martell, Elizabeth and Jones1, Lyndon (2013) Expression of MUC1 and MUC16 in tears and conjunctival epithelial cells collected from postmenopausal women. Molecular Vision, 19. pp. 970-979.

Rombach-Riegraf, Verena and Karle, Anette and Wolf, Babette and Sorde, Laetitia and Koepke, Stephan and Gottlieb, Sascha and Djidja, Marie-Claude and Baban, Aida and Spindeldreher, Sebastian and Koulov, Atanas and Kiessling, Andrea (2013) Aggregation of Human Recombinant Monoclonal Antibodies Influences the Capacity of Dendritic Cells to Stimulate Adaptive T-cell Responses In Vitro. PLoS One.

Romero, V and Fert-Bober, J and Nigrovic, PA and Darrah, E and Haque, UJ and Lee, DM and Van, EJ and Rosen, A and Andrade, F (2013) Immune-mediated pore-forming pathways induce cellular hypercitrullination and generate citrullinated autoantigens in rheumatoid arthritis. Science Translational Medicine.

Rot, A and McKimmie, C and Burt, CL and Pallas, KJ and Jamieson, T and Pruenster, M and Horuk, R and Nibbs, RJB and Graham, GJ (2013) Cell-Autonomous Regulation of Neutrophil Migration by the D6 Chemokine Decoy Receptor. JOURNAL OF IMMUNOLOGY. pp. 6450-6456.

Rothenbacher, D and Hoffmann, MM and Breitling, LP and Rajman, I and Koenig, W and Brenner, H (2013) Cytochrome P450 2C19*2 polymorphism in patients with stable coronary heart disease and risk for secondary cardiovascular disease events: results of a long-term follow-up study in routine clinical care - art. no. 61. BMC CARDIOVASCULAR DISORDERS. 61-.

Roubenoff, Ronenn (2013) The “Cytokine for Gerontologists” Has Some Company. Journal of Gerontology: Biological Sciences.

Rowe, Steven and Reeves, Ginger and Halthorne, Heather and Solomon, G Martin and Abbi, Smita and Renard, Didier and Lock, Ruth and Zhou, Ping and Danahay, Henry and Clancy, JP and Waltz, David (2013) Reduced Sodium Transport with Nasal Administration of the Prostasin Inhibitor Camostat in Cystic Fibrosis Subjects. Chest, 144 (1). pp. 200-207. ISSN None

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Rueeger, Heinrich and Lueoend, Rainer Martin and Machauer, Rainer and Veenstra, Siem and Jacobson, Laura and Staufenbiel, Matthias and Desrayaud, Sandrine and Rondeau, Jean-Michel and Moebitz, Henrik and Neumann, Ulf (2013) Discovery of Cyclic Sulfoxide Hydroxyethylamines as Potent and Selective β-Site APP-Cleaving Enzyme 1 (BACE1) Inhibitors: Structure Based Design and in Vivo Reduction of Amyloid β-Peptides. Bioorganic & Medicinal Chemistry Letters, 23. pp. 5300-5306.

Ruffner, Heinz (2013) Master thesis: Study of the Yap-Hippo and Wnt Pathways for Intestinal Regeneration in an Ex Vivo Small Intestinal 3D Organoid Model. Hochschule Mannheim. Master thesis, not published, presented to supervisor at Hochschule Mannheim under CDA..

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Schluepen, Christina and Malito, Enrico and Marongiu, Ambra and Schirle, Markus and Mc Whinnie, Elizabeth and Lo Surdo, Paola and Biancucci, Marco and Falugi, Fabiana and Nardi Dei Da Filicaia Dotti, Vincenzo and Marchi, Sara and Fontana, Maria Rita and Lombardi, Benedetta and De Falco, Maria Grazia and Rinaudo, Daniela and Spraggon, Glen and Grandi, Guido and Nissum, Mikkel and Bagnoli, Fabio and Bottomley, Matthew James and Liberatori, Sabrina (2013) A novel family of highly conserved antigens that induce protective immunity against Staphylococcus aureus. Biochemical journal, 455 (3). pp. 273-284. ISSN 1470-8728; 0264-6021

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Schutzius, G and Bleckmann, D and Kapps-Fouthier, S and di Giorgio, F and Gerhartz, B and Weiss, A (2013) A quantitative homogeneous assay for fragile X mental retardation 1 protein - art. no. 8. JOURNAL OF NEURODEVELOPMENTAL DISORDERS, 5 (1). p. 8. ISSN 1866-1947

Schutzius, Gabi and Bleckmann, Dorothee and Kapps-Fouthier, Sandra and Di Giorgio, Francesco and Gerhartz, Bernd and Weiss, Andreas (2013) A high-throughput compatible quantitative homogenous assay for Fragile X Mental Retardation 1 Protein. Journal for Neurodevelopmental Disorders, 5 (1). p. 8. ISSN 1866-1947

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Scuto, A and Kirschbaum, M and Buettner, R and Kujawski, M and Cermak, JM and Atadja, P and Jove, R (2013) SIRT1 activation enhances HDAC inhibition-mediated upregulation of GADD45G by repressing the binding of NF-kappa B/STAT3 complex to its promoter in malignant lymphoid cells - art. no. e635. CELL DEATH & DISEASE.

Sen, A and Dimlich, DN and Guruharsha, KG and Kankel, MW and Hori, K and Yokokura, T and Brachat, S and Richardson, D and Loureiro, J and Sivasankaran, R and Curtis, D and Davidow, LS and Rubin, LL and Hart, AC and Van Vactor, D and Artavanis-Tsakonas, S (2013) Genetic circuitry of Survival motor neuron, the gene underlying spinal muscular atrophy. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. E2371-E2380.

Sharma, S. and deVries, E.G. and Infante, J.R. and Oldenhuis, C.N. and Gietema, J.A. and Yang, Lin and Bilic, Sanela and Parker, Kathryn and Goldbrunner, Michael and Scott, Jeffrey and Burris, H.A. (2013) Safety, Pharmacokinetics, and Pharmacodynamics of the DR5 Antibody LBY135 Alone and in Combination with Capecitabine in Patients with Advanced Solid Tumors. Investigational New Drugs. ISSN 0167-6997

Shcheglovitov, A and Shcheglovitova, O and Yazawa, M and Portmann, T and Shu, R and Sebastiano, V and Krawisz, A and Froehlich, W and Bernstein, JA and Hallmayer, JF and Dolmetsch, RE (2013) SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients. NATURE. pp. 267-271.

Shi, Pei-Yong and Zhang, Bo (2013) Report of the fifth symposium on emerging viral diseases. Virologica Sinica, 28 (2). pp. 63-64. ISSN 1674-0769

Shidong, JIa and Massimo, Loda and Thomas, Roberts (2013) Opposing effects of androgen deprivation and targeted therapy on prostate cancer prevention. Cancer Discovery, 3 (1). pp. 44-51. ISSN 2159-8274

Shieh, Mae Mae Yi Fong and Thompson, Corinne and My, Phan Vu Tra and Van, Thi Thuy Linh and Tediosi, Fabrizio and Merson, Laura and Farrar, Jeremy and Ha, Manh Tuan and Ho, Lu Viet and Pham, Thi Ngoc Tuyet and Baker, Stephen (2013) Policy of free healthcare for children under six in Vietnam: assessment of its non-usage during hospitalization for diarrhea in Ho Chi Minh City. Tropical Medicine & International Health.

Shimada, Kenji and Filipuzzi, Ireos and Helliwell, Stephen and Studer, Christian and Hoepfner, Dominic and Movva, Rao and Gasser, Susan and Stahl, Michael and Loewith, Robbie (2013) TORC2 signaling pathway guarantees genome stability in the face of DNA strand breaks. Molecular Cell, 51 (6). pp. 829-839. ISSN 1097-2765

Shinde, DD and Kim, H and Choi, J and Pan, W and Bae, SK and Yeo, C and Shon, J and Kim, D and Shin, JG (2013) Different effects of clopidogrel and clarithromycin on the enantioselective pharmacokinetics of sibutramine and its active metabolites in healthy subjects. Journal of Clinical Pharmacology. pp. 550-558.

Shou, Jianyong (2013) Inhibition of H3K9 Methyltransferase G9a/GLP Prevents Ototoxic and Ongoing Hair Cell Death. Cell Death and Diseases, 4 (e506). ISSN 2041-4889

Shultz, Michael (2013) Setting expectations in molecular optimizations: Strengths and limitations of commonly used composite parameters. Bioorganic and Medicinal Chemistry Letters, 23 (21). pp. 5980-5991. ISSN 0960-894X

Shultz, Michael (2013) The thermodynamic basis for the use of lipophilic efficiency (LipE) in enthalpic optimizations. Bioorganic and Medicinal Chemistry Letters, 23 (21). pp. 5992-6000. ISSN 0960-894X

Shultz, Michael and Kirby, Christina and Firestone, Brant and Fan, Jianmei and Chen, Christine and Chen, Zhuoliang and Cheung, Atwood and Chin, Donovan and DiPietro, Lucian and Fazal, Aleem and Feng, Yun and Fortin, Pascal and Gould, Ty and Huangshu, Lei and Lenoir, Francois and Majumdar, Dyuti and Ochala, Etienne and Palermo, Mark and Pham, Ly and Pu, Minying and Smith, Troy and Tomlinson, Ronald and Toure, Bakary-Barry and Visser, Michael and Wang, Run-Ming and Waters, Nigel and Shao, Wenlin (2013) Identification of NVP-TNKS656: The use of structure-efficiency relationships to generate a highly potent, selective, and orally active tankyrase inhibitor. Journal of Medicinal Chemistry, 56 (16). pp. 6495-6511. ISSN 0022-2623

Sitnick, MT and Basantani, MK and Cai, L and Schoiswohl, G and Yazbeck, CF and Distefano, G and Ritov, V and DeLany, JP and Schreiber, R and Stolz, DB and Gardner, NP and Kienesberger, PC and Pulinilkunnil, T and Zechner, R and Goodpaster, BH and Coen, P and Kershaw, EE (2013) Skeletal Muscle Triacylglycerol Hydrolysis Does Not Influence Metabolic Complications of Obesity. DIABETES. pp. 3350-3361.

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Skvara, Hans and Burnett, Patrick and Jones, Julie and Plassmann, Peter and Thirion, Jean-Philippe (2013) Quantification of skin lesions with a 3D stereovision camera system: Validation and clinical applications. Skin Research and Technology, 19 (1). e182-190. ISSN 0909-752X

Slomianka, L and Drenth, T and Cavegn, N and Menges, D and Lazic, SE and Phalanndwa, M and Chimimba, CT and Amrein, I (2013) The hippocampus of the eastern rock sengi: Cytoarchitecture, markers of neuronal function, principal cell numbers, and adult neurogenesis. Frontiers in Neuroanatomy.

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Yrjola, S and Kalliokoski, T and Laitinen, T and Poso, A and Parkkari, T and Nevalainen, T (2013) Discovery of novel cannabinoid receptor ligands by a virtual screening approach: Further development of 2,4,6-trisubstituted 1,3,5-triazines as CB2 agonists. European Journal of Pharmaceutical Sciences. pp. 9-20.

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Zhang, L and Zhou, F and GarciadeVinuesa, A and deKruijf, E and Mesker, W and Hui, L and Drabsch, Y and Li, Y and Bauer, A and Rousseau, A and Sheppard, K and Mickanin, C and Kuppen, P and Lu, C and tenDijke, P (2013) TRAF4 Promotes TGF-beta Receptor Signaling and Drives Breast Cancer Metastasis. MOLECULAR CELL. pp. 559-572.

Zhang, T and Li, Y and Zou, P and Yu, J and McEachern, D and Wang, S and Sun, D (2013) Physiologically based pharmacokinetic and pharmacodynamic modeling of an antagonist (SM-406/AT-406) of multiple inhibitor of apoptosis proteins (IAPs) in a mouse xenograft model of human breast cancer. Biopharmaceutics and Drug Disposition. pp. 348-359.

Zhang, Tao and Yanyan , Li and Zou, Peng and Yu, Jing-yu and McEachern, Donna and Wang, Shaomeng and Sun, Duxin (2013) Physiologically based pharmacokinetic and pharmacodynamic modeling of an antagonist (SM-406/AT-406) of multiple inhibitor of apoptosis proteins (IAPs) in a mouse xenograft model of human breast cancer. Biopharmaceutics and Drug Disposition, 34 (6). pp. 348-359. ISSN 0142-2782

Zhang, X and Boutros, M (2013) A novel phenotypic dissimilarity method for image-based high-throughput screens. BMC Bioinformatics.

Zhang, X and Zhang, J and Bauer, A and Zhang, L and Selinger, DW and Lu, CX and ten Dijke, P (2013) Fine-tuning BMP7 signalling in adipogenesis by UBE2O/E2-230K-mediated monoubiquitination of SMAD6. EMBO JOURNAL. pp. 996-1007.

Zheng, Guishan and Schaefer, Michael and Karplus, Martin (2013) Hemoglobin Bohr Effects: Analysis of the Histidine Residue Contributions. Biochemistry.

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Zitzmann, Kathrin and Vlotides, Galina Ailer and Auernhammer, Christoph J (2013) Potent antitumor activity of novel HSP90 inhibitors AUY922 and HSP990 in neuroendocrine carcinoid cells. International Journal of Oncology, 43 (6). pp. 1824-1832. ISSN 1791-2423

Züst, Roland and Dong, Hongping and Li, Xiao-Feng and Chang, David and Zhang, Bo and Jiang, Tao and Li, Shi-Hua and Deng, Yong-Qiang and Ellis, Brett R and Ellis, Esther M and Qin, Cheng-Feng and Shi, Pei-Yong and Fink, Katja (2013) Rational Design of a Live Attenuated Dengue Vaccine: 2′-O-Methyltransferase Mutants Are Highly Attenuated and Immunogenic in Mice and Macaques. PLoS Pathogens, 9 (8). ISSN 1553-7366

This list was generated on Mon Dec 9 05:24:10 2019 UTC.

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