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Kinase-Kernel Models: Accurate Chemogenomic Method for the Entire Human Kinome

Tian, Li and Mukherjee, Prasenjit and Martin, Eric (2013) Kinase-Kernel Models: Accurate Chemogenomic Method for the Entire Human Kinome. Molecular Informatics.

Abstract

Chemogenomic kinase-kernel virtual screening models interpolate between very accurate, empirically-trained Profile-QSAR models of the nearest binding-site homologues with IC50 assay data. Between them, activity has been predicted for the entire human kinome.

Item Type: Article
Keywords: Kernel, Chemogenomics, Kinomics, Virtual screening, Chemoinformatics
Date Deposited: 27 Apr 2016 23:45
Last Modified: 27 Apr 2016 23:45
URI: https://oak.novartis.com/id/eprint/10279

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