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Recent advances in small molecule target identification methods

Jain, Rishi and Beckwith, Rohan (2013) Recent advances in small molecule target identification methods. Annual Reports in Medicinal Chemistry, 48. pp. 301-315. ISSN 0065-7743


In this chapter, four major target identification approaches including affinity-based proteomics, in silico target prediction, drug resistance-sequencing, and yeast-based approaches are discussed with demonstrative examples from the last few years. © 2013 Elsevier Inc.

Item Type: Article
Keywords: Affinity-based proteomics Chemical probes Drug resistance Haploinsufficiency profiling In silico target prediction Mechanism of action Phenotypic drug discovery Polypharmacology Target identification Yeast three hybrid
Date Deposited: 23 Nov 2017 00:45
Last Modified: 25 Jan 2019 00:46


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