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Mass Spectrometric Imaging Applied to Biomedical Research

Stoeckli, Markus, Staab, Dieter and Morandi, Gregory (2013) Mass Spectrometric Imaging Applied to Biomedical Research. Chimia, 57 (4).


Mass spectrometric imaging (MSI) stands out of the available molecular imaging technologies due to its ability to simultaneously map multiple analytes without the need for labeling. This makes it the method of choice for applications where labeling is not amenable, or where many (up to hundreds) analytes are to be monitored in in one samples. Since the technology is based on the identification of the analyte molecules by their exact mass and/or fragmentation pattern, it also allows imaging a wide mass range without having to know the analytes a priori to the measurement. While the potential of this technology was early on recognized, it was not till recently that new technological advances made it routinely applicable to biomedical research.

Item Type: Article
Keywords: MSI; molecular imaging
Date Deposited: 13 Oct 2015 13:13
Last Modified: 13 Oct 2015 13:13


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