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Items where Year is 2013

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Number of items: 514.

UNSPECIFIED (2013) Generation of a parvovirus B19 vaccine candidate. VACCINE. S0264-.

Abazeed, Mohamed E., Adams, Drew J., Hurov, Kristen, Tamayo, Pablo, Creighton, Chad J., Sonkin, Dmitriy, Giacomelli, Andrew O., Pashtan, Itai, Du, Charles, Fries, Daniel F., Wong, Kwok-Kin, Mesirov, Jill P., Loeffler, Jay S., Schreiber, Stuart L., Hammerman, Peter S. and Meyerson, Matthew (2013) Integrative radiogenomic profiling of squamous cell lung cancer. Cancer Research, 73 (20). pp. 6289-6298. ISSN 0008-5472.CAN-13-1616

Adamo, Roberto, Proietti, Daniela, Gavini, Massimiliano, Romano, Maria Rosaria, Maclennan, Calman Alexander, Costantino, Paolo and Berti, Francesco (2013) Meningococcal X polysaccharide quantification by high-performance anion-exchange chromatography with pulsed amperometric detection using synthetic N-acetylglucosamine-4-phosphate as standard. Analytical Biochemistry, 44. pp. 259-261.

Alajati, A, Sausgruber, N, Aceto, N, Duss, S, Sarret, S, Voshol, H, Bonenfant, D and Bentires-Alj, M (2013) Mammary Tumor Formation and Metastasis Evoked by a HER2 Splice Variant. CANCER RESEARCH. pp. 5320-5327.

Alderton, WK, Anderson, RJ, Collingwood, SP and Pryde, DC (2013) THERAPEUTIC OPPORTUNITIES IN INFECTIOUS DISEASES HIGHLIGHTS FROM THE SOCIETY OF MEDICINES RESEARCH SYMPOSIUM, HELD ON MARCH 14TH 2013 AT THE NATIONAL HEART & LUNG INSTITUTE, LONDON, UK. DRUGS OF THE FUTURE. pp. 347-354.

Altstein, L and Li, G (2013) Latent Subgroup Analysis of a Randomized Clinical Trial through a Semiparametric Accelerated Failure Time Mixture Model. BIOMETRICS. pp. 52-61.

Anna-Lena, Gessler and Warncke, Max (2013) Master Thesis: Pathogenese und Keimzentrumsreaktion im Typ 1 Diabetes Mausmodell (Pathogenesis and germinal center reaction in the NOD T1D mouse model). University Freiburg.

Antoine, Daniel, Dear, James, Starkey-Lewis, Philip, Platt, Vivien, Coyle, Judy, Masson, Moyra, Thanacoody, Ruben, Gray, Alastair, Moggs, Jonathan, Bateman, Nicholas, Goldring, Christopher and Park, Kevin (2013) Mechanistic biomarkers provide early and sensitive detection of paracetamol-induced acute liver injury at first presentation to hospital. Journal of Hepatology, 58. ISSN 0168-8278

Antony, D, Becker-Heck, A, Zariwala, MA, Schmidts, M, Onoufriadis, A, Forouhan, M, Wilson, R, Taylor-Cox, T, Dewar, A, Jackson, C, Goggin, P, Loges, NT, Olbrich, H, Jaspers, M, Jorissen, M, Leigh, MW, Wolf, WE, Daniels, MLA, Noone, PG, Ferkol, TW, Sagel, SD, Rosenfeld, M, Rutman, A, Dixit, A, O'Callaghan, C, Lucas, JS, Hogg, C, Scambler, PJ, Emes, RD, Chung, EMK, Shoemark, A, Knowles, MR, Omran, H and Mitchison, HM (2013) Mutations in CCDC39 and CCDC40 are the Major Cause of Primary Ciliary Dyskinesia with Axonemal Disorganization and Absent Inner Dynein Arms. Human Mutation. pp. 462-472.

Arias, HR, Fedorov, NB, Benson, LC, Lippiello, PM, Gatto, GJ, Feuerbach, Dominik and Ortells, MC (2013) Functional and Structural Interaction of (-)-Reboxetine with the Human alpha4beta2 Nicotinic Acetylcholine Receptor. Journal of Pharmacology and experimental therapeutics, 344 (3). pp. 113-123. ISSN 112.197905

Arias, HR, Lopez, JJ, Feuerbach, D, Fierro, A, Ortells, MO and Perez, EG (2013) The International Journal of Biochemistry & Cell Biology. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY. pp. 2420-2430.

Arias, HR, Ortells, MO and Feuerbach, Dominik (2013) Interaction of (-)-reboxetine with nicotinic acetylcholine receptors in different conformational states. International Journal of biochemistry and cell biology.

Assenberg, Rene, Wan, Paul, Geisse, Sabine and Mayr, Lorenz (2013) Advances in heterologous expression of recombinant proteins. Current opinion in Structural Biology, 23 (3). pp. 393-402. ISSN 0959-440X

Atassi, F, Behme, RJ and Patel, PJ (2013) Mesomorphous versus traces of crystallinity: The itraconazole example. THERMOCHIMICA ACTA. pp. 133-139.

Auclair, JR, Johnson, JL, Liu, Q, Salisbury, JP, Rotunno, MS, Petsko, GA, Ringe, D, Brown, J, Bosco, DA and Agar, JN (2013) Post-translational modification by cysteine protects Cu/Zn-superoxide dismutase from oxidative damage. Biochemistry. pp. 6137-6144.

Auld, D, Lea, W, Davis, MI and Simeonov, A (2013) Literature Search and Review: 3D Cocultures of Multiple Cell Types: What do they do and Where do they Go? Assay and Drug Development Technologies, 11 (8). pp. 457-467.

Auld, D, Lea, W, Davis, MI and Simeonov, A (2013) Literature Search and Review: BLI Coupled with DNA Tetrahedron. Assay and Drug Development Technologies, 11 (3). pp. 139-151. ISSN 1540-658X1557-8127

Auld, D, Lea, W, Davis, MI and Simeonov, A (2013) Literature Search and Review: Better Biosensors for FBDD. Assay and Drug Development Technologies, 11 (5). pp. 289-298. ISSN 1540-658X1557-8127

Auld, D, Lea, W, Davis, MI and Simeonov, A (2013) Literature Search and Review: Detected Through A Quick Glance. Assay and Drug Development Technologies, 11 (1). pp. 1-8. ISSN 1540-658X1557-8127

Auld, DS, Veith, H and Cali, JJ (2013) Bioluminescent assays for cytochrome P450 enzymes. Methods in Molecular Biology. pp. 1-9.

Auld, Douglas, Breault, Lyne, Pandey, Pramod, Ho, Pei-I, Harbinski, Fred and Hill, William (2013) Reporter enzyme inhibitor study to aid assembly of orthogonal reporter gene assays. ACS Chemical Biology, 8 (5). pp. 1009-1017. ISSN 1554-8929

Azzaoui, Kamal, Jacoby, Edgar, Senger, Stefan, Cuadrado Rodríguez, Emiliano, Loza, Mabel, Zdrazil, Barbara, Pinto, Marta, Williams, Antony J, de la Torre, Victor, Mestres, Jordi, Taboureau, Olivier, Rarey, Matthias and Ecker, Gerhard F (2013) Analysis of the scientific competency questions followed by the IMI OpenPHACTS consortium for the development of the semantic web-based molecular information system OPS. Drug Discovery Today, 18 (17-18). pp. 843-852. ISSN 1878-5832

Baba, Nobuyasu, Van, VuQuang, Wakahara, Keiko, Weckbecker, Gisbert, Kolbinger, Frank, Heusser, Christoph, Huber, Thomas, Welzenbach, Karl and Sarfati, Marika (2013) CD47 fusion protein targets CD172a+ cells in Crohn's disease and dampens the production of IL-1β and TNF. J Exp Med..

Baeten, Dominique, Baraliakos, Xenofon, Braun, Juergen, Sieper, Joachim, Emery, Paul, Van der Heijde, Desiree, McInnes, Iain, Van Laar, Jacob, Landewé, Robert, Wordsworth, Paul, Wollenhaupt, Jürgen, Kellner, Herbert, Paramarta, Jacqueline, Wei, Jiawei, Brachat, Arndt Holger, Bek, Stephan, Laurent, Didier, Li, Yali, Bertolino, Arthur, Gsteiger, Sandro, Wright, Andrew and Hueber, Wolfgang (2013) Anti-interleukin-17A monoclonal antibody secukinumab in treatment of ankylosing spondylitis: A randomised, double-blind, placebo-controlled trial. The Lancet, 382 (9906). pp. 1705-1713. ISSN 01406736

Balibar, Carl, Mcguire, Dorothy and Dean, Charles (2013) Elongation Factor P is dispensable in Escherichia coli and Pseudomonas aeruginosa. Current Microbiology, 284. ISSN 0343-8651

Ballabeni, A, Zamponi, R, Moore, JK, Helin, K and Kirschner, MW (2013) Geminin deploys multiple mechanisms to regulate Cdt1 before cell division thus ensuring the proper execution of DNA replication. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. E2848-E2853.

Ballard, Sarah, Engeloch, Caroline and Baeschlin, Daniel (2013) Automated compound management evolves to meet the drug discovery demands of the future. Drug Discovery world.

Baltus, Christine, Press, Neil, Coles, Simon, Tizzard, Graham, Spencer, John, Chuckowree, Irina and Day, Iain (2013) Olefin cross-metathesis/Suzuki-Miyaura reactions on 4-vinylphenylboronic acid pinacol ester. Tetrahedron Letters, 54 (10). pp. 1211-1217. ISSN 0040-4039

Bardelli, M, Alleri, L, Angiolini, F, Buricchi, F, Tavarini, S, Sammicheli, C, Nuti, S, Degl'Innocenti, E, Isnardi, I, Fragapane, E, Del, GG, Castellino, F and Galli, G (2013) Ex Vivo Analysis of Human Memory B Lymphocytes Specific for A and B Influenza Hemagglutinin by Polychromatic Flow-Cytometry. PLoS One.

Barnes, David, Jain, Monish, Bell, Leslie, Ferreira, Suzie, Cohen, Scott, Chen, Xiao-Hui, Amin, Jakal, Snodgrass, Bradley and Hatsis, Panagiotis (2013) Metabolically Stable tert-Butyl Replacement. ACS Medicinal Chemistry Letters. ISSN 1948-5875

Barteau, Samuel, Heudi, Olivier, Kameni Tcheudji, Jacques, Streckfuss, Judith, Tukulula, Matshawandile, Njoroge, Mathew, Mugumbate, Grace, Little, Susan, Grut, Jiri, Rosenthal, Philip J, Wan, Baojie, Franzblau, Scott G and Chibale, Kelly (2013) Tetrazole-based deoxyamodiaquines: synthesis, ADME/PK profiling and pharmacological evaluation as potential antimalarial and antituberculosis agents. Journal of medicinal chemistry, 21 (17). pp. 4904-4913. ISSN 09680896

Bartels, Christian, Looby, Michael, Sechaud, Romain and Kaiser, Guenther (2013) Determination of the pharmacokinetics of glycopyrronium in the lung using a population pharmacokinetic modeling approach. Britisch Journal of Clinical Pharmacology. ISSN 0306-5251

Basu, A, Bodycombe, NE, Cheah, JH, Price, EV, Liu, K, Schaefer, GI, Ebright, RY, Stewart, ML, Ito, D, Wang, S, Bracha, AL, Liefeld, T, Wawer, M, Gilbert, JC, Wilson, AJ, Stransky, N, Kryukov, GV, Dancik, V, Barretina, J, Garraway, LA, Hon, CSY, Munoz, B, Bittker, JA, Stockwell, BR, Khabele, D, Stern, AM, Clemons, PA, Shamji, AF and Schreiber, SL (2013) An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules. Cell. pp. 1151-1161.

Beck, Valerie, Leighton-Davies, Juliet, Beibel, Martin, Roma, Guglielmo, Oakeley, Edward James, Hamon, Jacques, Barbieri, Samuel, Preuss, Inga, Lasbennes-Eckerlen, Marie-Christine, Sailer, Andreas, Suply, Thomas, Seuwen, Klaus, Parker, Christian, Bassilana, Frederic, Lannoy, Vincent, bernard, Jerome and Hannedouche, Sebastien (2013) The identification of the C3a Receptor (C3AR1) as the target of the VGF derived peptide TLQP-21 in rodent cells. Journal of Biological Chemistry, 288 (38). pp. 27434-27443. ISSN 0021-9258

Beckett, Martin (2013) Book Review: Practical Process Research and Development, second edition by Neal G. Anderson, Elsevier, 2012. Chemistry and Industry, Januar. p. 49.

Beckett, Martin (2013) Book review: Organic Synthesis: State of the Art 2009-2011 by Douglass F Taber, Wiley, 2013. Chemistry and Industry, Septem (Septem). pp. 46-47.

Beckman, David, Schneider, Marilynn, Decristofaro, Marc, Samadfam, Rana, Smith, Susan and Pouliot, Louise (2013) Assessment of a nonsteroidal aromatase inhibitor, letrozole, in juvenile rats. Birth Defects Research, 98 (5). pp. 374-390. ISSN 1542-9741

Beckman, David, Youreneff, Maureen and Butt, Mark (2013) Neurotoxicity assessment of artemether in juvenile rats. Birth Defects Research Part B: Developmental and Reproductive Toxicology, 98 (2). pp. 183-199. ISSN 1542-9741

Beckmann, N and Kaltashov, IA (2013) Delivery of biopharmaceuticals: advanced analytical and biophysical methods Preface. ADVANCED DRUG DELIVERY REVIEWS. 1001-.

Bentz, J, O'Connor, MP, Bednarczyk, D, Coleman, J, Lee, C, Palm, J, Pak, YA, Perloff, ES, Reyner, E, Balimane, P, Brannstrom, M, Chu, X, Funk, C, Guo, A, Hanna, I, Heredi-Szabo, K, Hillgren, K, Li, L, Hollnack-Pusch, E, Jamei, M, Lin, X, Mason, AK, Neuhoff, S, Patel, A, Podila, L, Plise, E, Rajaraman, G, Salphati, L, Sands, E, Taub, ME, Taur, JS, Weitz, D, Wortelboer, HM, Xia, CQ, Xiao, G, Yabut, J, Yamagata, T, Zhang, L and Ellens, H (2013) Variability in P-Glycoprotein Inhibitory Potency (IC50) Using Various in Vitro Experimental Systems: Implications for Universal Digoxin Drug-Drug Interaction Risk Assessment Decision Criteria. DRUG METABOLISM AND DISPOSITION. pp. 1347-1366.

Bereau, T, Kramer, C, Monnard, FW, Nogueira, ES, Ward, TR and Meuwly, M (2013) Scoring Multipole Electrostatics in Condensed-Phase Atomistic Simulations. JOURNAL OF PHYSICAL CHEMISTRY B. pp. 5460-5471.

Betschart, Claudia, Hintermann, Samuel, Behnke, Dirk, Cotesta, Simona, Fendt, Markus, Gee, Christine, Jacobson, Laura, Laue, Grit, Ofner, Silvio, Chaudhari, Vinod, Badiger, Sangamesh, Pandit, Chetan, Wagner, Juergen and Hoyer, Daniel (2013) Identification of a Novel Series of Orexin Receptor Antagonists with a Distinct Effect on Sleep Architecture for the Treatment of Insomnia. Journal of Medicinal Chemistry.

Bian, X, Fu, J, Plaza, A, Herrmann, J, Pistorius, D, Stewart, AF, Zhang, Y and Muller, R (2013) In Vivo Evidence for a Prodrug Activation Mechanism during Colibactin Maturation. ChemBioChem, 14 (10). pp. 1194-1197. ISSN 14394227

Bignon, Alexandre, Gaudin, Françoise, Hémon, Patrice, Tharinger, Hugo, Loetscher, Pius, Peuchmaur, Michel, Berrebi, Dominique and Balabanian, Karl (2013) Pivotal role of Ccr1 in murine lupus nephritis. Journal of Immunology.

Billedeau, RJ, Klein, KR, Kaplan, D and Lou, Y (2013) A New Pyrrole Synthesis via Silver(I)-Catalyzed Cycloaddition of Vinylogous Diazoester and Nitrile. ORGANIC LETTERS. pp. 1421-1423.

Billich, Andreas, Baumruker, Thomas, Beerli, Christian, Bigaud, Marc, Bruns, Christian, Calzascia, Thomas, Isken, Andrea, Kinzel, Bernd, Loetscher, Erika, Metzler, Barbara, Mueller, Matthias, Nuesslein-Hildesheim, Barbara and Kleylein-Sohn, Bernadette (2013) Partial deficiency of sphingosine-1-phosphate lyase confers protection in experimental autoimmune encephalomyelitis. PLOS ONE, 8 (3). e59630. ISSN 1932-6203

Billich, Andreas, Beerli, Christian, Bruns, Christian and Loetscher, Erika (2013) Cellular assay for the characterization of sphingosine-1-phosphate lyase inhibitors. Analytical Biochemistry, 434 (2). pp. 247-253. ISSN 0003-2697

Biukovic, Goran, Basak, Sandip, Manimekalai, Malathy Sony Subramanian, Rishikeshan, Sankaranarayanana, Roessle, Manfred, Dick, Thomas, Rao, Srinivasa, Hunke, Cornelia and Gruber, Gerhard (2013) Variations of subunit Varepsilon of the Mycobacterium tuberculosis F-1Fo ATP Synthase and Novel Model for Mechanism of Action of the Tuberculosis Drug TMC207. Antimicrobial Agents and Chemotherapy, 57 (1). pp. 168-176. ISSN 0066-4804

Blache, U, Silvan, U, Plodinec, M, Suetterlin, R, Jakob, R, Klebba, I, Bentires-Alj, M, Aebi, U and Schoenenberger, CA (2013) A Tumorigenic Actin Mutant Alters Fibroblast Morphology and Multicellular Assembly Properties. CYTOSKELETON. pp. 635-650.

Bobardt, M, Hopkins, S, Baugh, J, Chatterji, U, Hernandez, F, Hiscott, J, Sluder, A, Lin, K and Gallay, PA (2013) HCV NS5A and IRF9 compete for CypA binding. JOURNAL OF HEPATOLOGY. pp. 16-23.

Bolton, SA, Sutton, JC, Anumula, R, Bisacchi, GS, Jacobson, B, Slusarchyk, WA, Treuner, UD, Wu, SC, Zhao, G, Pi, Z, Sheriff, S, Smirk, RA, Bisaha, S, Cheney, DL, Wei, A, Schumacher, WA, Hartl, KS, Liu, E, Zahler, R and Seiler, SM (2013) Discovery of nonbenzamidine factor VIla inhibitors using a biaryl acid scaffold. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. pp. 5239-5243.

Bouchez, Laure, Ruffner, Heinz, Spanka, Carsten and Patoor, Maude (2013) Synthesis of a Series of Promising Isobenzofurans for the Reduction of Acute Mucositis Risk after Chemo- and Radiotherapy. Synlett- special edition.

Boulton, C, David, OJ, Meiser, K and Schmouder, R (2013) Tolerability and pulmonary pharmacodynamic effects during treatment initiation of once-daily oral fingolimod in subjects with moderate asthma. Clinical Pharmacology in Drug Development. pp. 2-10.

Bowman, SK, Simon, MD, Deaton, AM, Tolstorukov, M, Borowsky, ML and Kingston, RE (2013) Multiplexed Illumina sequencing libraries from picogram quantities of DNA. BMC Genomics.

Brauchle, Michael, Yao, Zhiping, Arora, Rishi, Clay, Ieuan, Inverardi, Bruno, Gerrits, Bertran, Voshol, Johannes, Bauer, Andreas, Schuebeler, Dirk, Bouwmeester, Antonius, Ruffner, Heinz and Thigale, Sachin (2013) A systematic comparison of enzymatic activity and protein interaction analysis of the KDM3 histone demethylase subfamily. PLOS ONE, 8 (4). e60549. ISSN 1932-6203

Breckner, Anke, Gerwin, Nicole, Richter, Jens, Rausch, Martin, Marcellin, David and Ganz, Magdalena (2013) Effect of calstabin1 depletion on calcium transients and energy utilization in FDB muscle fibers and potential treatment opportunities based on RyR1 stabilizers. The Journal of Biological Chemistry, 8 (11). ISSN 1932-6203

Breitenstein, Werner, Cumin, Frederic, Ehrhardt, Claus, Jacoby, Edgar, Lorthiois, Edwige, Ostermann, Nils, Sellner, Holger, Kosaka, Takatoshi, Webb, Randy, Hassiepen, Ulrich, Wagner, Beatrix and Maibaum, Juergen Klaus (2013) Discovery from in silico 3D Pharmacophore Searches of Novel 3(R),4(S)-disubstituted Pyrrolidine Inhibitors of the Human Aspartyl Protease Renin. Journal of Medicinal Chemistry, 56 (6). pp. 2207-2217. ISSN 0022-2623

Bridges, James P., Ludwig, Marie-Gabrielle, Mueller, Matthias, Kinzel, Bernd, Sato, Atsuyasu, Xu, Yan, Whitsett, Jeffery A. and Ikegami, Machiko (2013) The Orphan G Protein-Coupled Receptor GPR116 Regulates Pulmonary Surfactant Pool Size. American Journal of Respiratory Cell and Molecular Biology. ISSN 1044-1549

Britschgi, Adrian, Bill, Anke, Brinkhaus, Heike, Rothwell, Christopher, Clay, Ieuan, Duss, Stephan, Rebhan, Michael, Raman, Pichai, Guy, Chantale, Wetzel, Kristie, George, Elizabeth, Popa, Oana, Lilley, Sarah, Choudhury, Hedaythul, Gosling, Martin, Wang, Louis, Fitzgerald, Stephanie, Borawski, Jason, Baffoe, Jonathan, Labow, Mark, Gaither, Larry and Bentires-Alj, Mohamed (2013) Inhibition of the 11q13 amplified calcium activated chloride channel ANO1 reduces Head and Neck and Breast cancer growth. PNAS, 110 (11). E1026-E1034. ISSN 0027-8424

Bulliard, Yannick, Jolicoeur, Rose, Windman, Maurice, Rue, Sarah M, Ettenberg, Seth, Knee, Deborah A, Wilson, Nicholas S, Dranoff, Glenn and Brogdon, Jennifer L (2013) Activating Fc γ receptors contribute to the antitumor activities of immunoregulatory receptor-targeting antibodies. The Journal of Experimental Medicine, 210 (9). pp. 1685-1693. ISSN 1540-9538

Burger, Matthew, Han, Wooseok, Lan, Jiong, Nishiguchi, Gisele, Bellamacina, Cornelia, Lindvall, Mika, Atallah, Gordana, Ding, Yu, Mathur, Michelle, Mcbride, Christopher, Mieuli, Elizabeth, Muller, Kristine, Tamez Jr., Victoriano, Zhang, Yanchen, Huh, Kay, Feucht, Paul, Zavorotinskaya, Tatiana, Dai, Yumin, Holash, Jocelyn, Langowski, John and Garcia, Pablo (2013) Structure Guided Optimization, In Vitro Activity and In Vivo Activity of Pan-PIM Kinase Inhibitors. American Chemical Society Medicinal Chemistry Letters, 4 (12). pp. 1193-1197.

Burmester, Gerd, Durez, Patrick, Shestakova, Galina, Genovese, Mark, Schulze-Koops, Hendrik, Li, Yue, Lewitzky, Steven, Koroleva, Irina, Agarwal, Anni, Lee, David and Hueber, Wolfgang (2013) Caspase 8 modulates the polarisome to prevent lung fibrosis in a murine SSC-like disease model. Arthritis and Rheumatism, 65 (Suppl.). S1171. ISSN 00043591

Butendeich, Heike, Pierret, Noelle and Numao, Shin (2013) Evaluation of a liquid dispenser for assay development and enzymology in 1536 well format. Journal of Laboratory Automation, 18 (3). pp. 245-250. ISSN 2211-0682

Byun, M, Ma, CS, Akcay, A, Pedergnana, V, Palendira, U, Myoung, J, Avery, DT, Liu, Y, Abhyankar, A, Lorenzo, L, Schmidt, M, Lim, HK, Cassar, O, Migaud, M, Rozenberg, F, Canpolat, N, Aydogan, G, Fleckenstein, B, Bustamante, J, Picard, C, Gessain, A, Jouanguy, E, Cesarman, E, Olivier, M, Gros, P, Abel, L, Croft, M, Tangye, SG and Casanova, JL (2013) Inherited human OX40 deficiency underlying classic Kaposi sarcoma of childhood. JOURNAL OF EXPERIMENTAL MEDICINE. pp. 1743-1759.

Cai, Mi and Yang, Yi (2013) Targeted genome editing tools for disease modeling and gene therapy. Current Gene Therapy.

Cai, Xinming, Xu, Yongyao, Cheung, Atwood, Tomlinson, Ronald, Alcazer-Roman, Abel, Murphy, Leon, Billich, Andreas, Feng, Yan, Zhang, Bailin, Klumpp, Martin, Rondeau, Jean-Michel, Fazal, Aleem, Wilson, Christopher, Myer, Vic, Joberty, Gerard, Bouwmeester, Antonius, Labow, Mark, Finan, Peter, Porter, Jeffrey, Ploegh, Hidde, Baird, Daniel, De Camilli, Pietro, Tallarico, John and Huang, Qian (2013) PIKfyve, a Class III PI Kinase, Is the Target of the Small Molecular IL-12/IL-23 Inhibitor Apilimod and a Player in Toll-like Receptor Signaling. Chemistry & Biology, 20. pp. 912-921.

Callander, Gabrielle E., Olorunda, Morenike, Monna, Dominique, Schuepbach, Edi, Langenegger, Daniel, Betschart, Claudia, Hintermann, Samuel, Briard, Emmanuelle, Behnke, Dirk, Cotesta, Simona, Fendt, Markus, Laue, Grit, Ofner, Silvio, Gee, Christine, Jacobson, Laura and Hoyer, Daniel (2013) Kinetic properties of 'dual' orexin receptor antagonists at OX1 and Ox2 receptors. Frontiers in Neuroscience, Neuropharmacology., 7. p. 230. ISSN 1662-453X

Casado, P, Rodriguez-Prados, J, Cosulich, SC, Guichard, S, Vanhaesebroeck, B, Joel, S and Cutillas, PR (2013) Kinase-substrate enrichment analysis provides insights into the heterogeneity of signaling pathway activation in leukemia cells. Science Signaling. rs6-.

Castiello, MC, Bosticardo, M, Pala, F, Catucci, M, Chamberlain, N, van Zelm, MC, Driessen, GJ, Pac, M, Bernatowska, E, Scaramuzza, S, Aiuti, A, Sauer, AV, Traggiai, E, Meffre, E, Villa, A and van der Burg, M (2013) Wiskott-Aldrich Syndrome protein deficiency perturbs the homeostasis of B-cell compartment in humans. Autoimmunity.

Catanese, MT, Loureiro, J, Jones, CT, Dorner, M, von, HT and Rice, MC (2013) Different requirements for scavenger receptor class B type I in hepatitis C virus cell-free versus cell-to-cell transmission. Journal of Virology. pp. 8282-8293.

Chakraborty, Abhijit, Van, Linh, Skerjanec, Andrej, Floch, David, Klein, Ulf, Krammer, Gerhard, Sunkara, Gangadhar and Howard, Danny (2013) Pharmacokinetic and pharmacodynamic properties of canakinumab in patients with gouty arthritis. Journal of Clinical Pharmacology, 53 (12). pp. 1240-1251. ISSN 0091-2700

Chan, HCS, Kendrick, J, Neumann, MA and Leusen, FJJ (2013) Towards ab initio screening of co-crystal formation through lattice energy calculations and crystal structure prediction of nicotinamide, isonicotinamide, picolinamide and paracetamol multi-component crystals. CRYSTENGCOMM. pp. 3799-3807.

Chandriani, Sanjay, Skewes-Cox, Peter, Zhong, Weidong, Ganem, Donald, Divers, Thomas J., Tennant, Bud C., Van Blaricum, Anita J. and Kistler, Amy (2013) Identification of a previously undescribed divergent virus from the Flaviviridae family in an outbreak of equine serum hepatitis. Proceedings of the National Academy of Sciences USA, 110 (15). E1407-1415. ISSN 0027-8424

Chang, Henry and Ganem, Donald (2013) A unique herpesviral transcriptional program in KSHV-infected lymphatic endothelial cells leads to mTORC1 activation and rapamycin sensitivity. Cell Host & Microbe, 13 (4). pp. 429-440. ISSN 1931-3128

Che, Jianwei, Guo, Zuojun, Li, Bo, Cheng, Li-Tien, Dzubiella, Joachim and McCammon, J. Andrew (2013) Evaluation of Hydration Free Energy by the Level-Set Variational Implicit-Solvent Model with the Coulomb-Field Approximation. Journal of chemical theory and computation. ISSN 1549-9618

Chen, Jinyun, Chung, Franklin, Yang, Guizhi, Pu, Minying, Gao, Hui, Jiang, Wei, Yin, Hong, Capka, Vladimir, Kasibhatla, Shailaja, Laffitte, Bryan, Pagliarini, Raymond, Chen, Yaoyu and Zhou, Wenlai (2013) Phosphoglycerate dehydrogenase is dispensable for breast tumor maintenance and growth. Oncotarget, 4 (12). pp. 2502-2511. ISSN 1949-2553

Chen, Y and Li, S (2013) Molecular signatures of chronic myeloid leukemia stem cells. Biomarker Research.

Chen, Yaoyu, Chen, Jinyun, Loo, Alice, Jaeger, Savina, Bagdasarian, Linda, Yu, Jianjun, Chung, Franklin, Korn, Joshua, Ruddy, David, Guo, Ribo, Mclaughlin, Megan, Stegmeier, Frank, Pagliarini, Raymond, Porter, Dale and Zhou, Wenlai (2013) Targeting HSF1 sensitizes cancer cells to HSP90 inhibitor. Oncotarget.

Cheng, CH, Leferovich, J, Zhang, XM, Bedelbaeva, K, Gourevitch, D, Hatcher, CJ, Basson, CT, Heber-Katz, E and Marx, KA (2013) Keratin gene expression profiles after digit amputation in C57BL/6 vs. regenerative MRL mice imply an early regenerative keratinocyte activated-like state. PHYSIOLOGICAL GENOMICS. pp. 409-421.

Cheng, DT, Kim, DK, Cockayne, DA, Belousov, A, Bitter, H, Cho, MH, Duvoix, A, Edwards, LD, Lomas, DA, Miller, BE, Reynaert, N, Tal-Singer, R, Wouters, EFM, Agusti, A, Fabbri, LM, Rames, A, Visvanathan, S, Rennard, SI, Jones, P, Parmar, H, MacNee, W, Wolff, G, Silverman, EK, Mayer, RJ and Pillai, SG (2013) Systemic Soluble Receptor for Advanced Glycation Endproducts Is a Biomarker of Emphysema and Associated with AGER Genetic Variants in Patients with Chronic Obstructive Pulmonary Disease. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. pp. 948-957.

Cheng, Tiewei, Roth, Beat, Woonyoung, Choi, Black, Peter, Dinney, Colin and McConkey, David J. (2013) Fibroblast growth factor receptors-1 and -3 play distinct roles in the regulation of bladder cancer growth and metastasis: Implications for therapeutic targeting. PLoS ONE, 8 (2). e57284-e57284. ISSN 1932-6203

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Hellman, Maarit, Piirainen, Henni, Jaakola, Veli-Pekka and Permi, Perttu (2013) Bridge over troubled proline: assignment of intrinsically disordered proteins using (HCA)CON(CAN)H and (HCA)N(CA)CO(N)H experiments concomitantly with HNCO and i(HCA)CO(CA)NH. Journal of Biomolecular NMR, 58 (1). pp. 49-60. ISSN 0925-2738

Heudi, Olivier, Maganda, Betty, Cortinovis, Agnes, Picard, Franck and Kretz, Olivier (2013) A fast and reliable reversed phase high performance liquid chromatography method for simultaneous determination of selected anti-retroviral and lumefantrine in human plasma. Journal of Chromatography B, 919/92. pp. 52-60. ISSN 1570-0232

Heudi, Olivier, Van Baar, Ben, Rohde, Morten, Wieling, Jaap, Verhaeghe, Tom, Lüdtke, Silke, De Vries, Ronald, White, Steve, Cobb, Zoe and Timmerman, Philip (2013) Internal standard addition in bioanalysis of dried blood spots: results from the EBF DBS-microsampling consortium. Bioanalysis, 5 (17). pp. 2137-2145. ISSN 1757-6180

Hill, RJ, Lou, Y and Tan, SL (2013) B-Cell Antigen Receptor Signaling in Chronic Lymphocytic Leukemia: Therapeutic Targets and Translational Opportunities. INTERNATIONAL REVIEWS OF IMMUNOLOGY. pp. 377-396.

Hoffman, Gregory, Rahal, Rami, Buxton, Frank, Mcallister, Gregory, Xiang, Xiaoqin, Frias, Elizabeth, Huber, Janina, Lindeman, Alicia, Chen, Dongshu, Bagdasarian, Linda, Romero, Rodrigo, Ramadan, Nadire, Phadke, Tanushree, Haas, Kristy, Jaskelioff, Mariela, Wilson, Boris, Meyer, Matthew, Saenz-Vash, Veronica, Zhai, Huili, Mclaughlin, Margaret, Charles, Roberts, Myer, Vic, Porter, Jeffrey, Keen, Nicholas, Mickanin, Craig, Stegmeier, Frank and Jagani, Zainab (2013) A functional screen of the epigenome identifies BRM/SMARCA2 as a critical synthetic lethal target in BRG1-deficient cancers. Molecular Cancer Therapeutics, 12 (11). ISSN 15357163

Hoffmaster, Keith, Brouwer, Kim, Keppler, Dietrich, Bow, Daniel, Cheng, Yaofeng, Lai, Yurong, Palm, Johan, Stieger, Bruno and Evers, Raymond (2013) In Vitro Methods to Support Transporter Evaluation in Drug Discovery and Development. Clinical Pharmacology and Experimental Therapeutics.

Holderfield, Matthew, Merritt, Hanne, Chan, John, Wallroth, Marco, Tandeske, Laura, Zhai, Huili, Hardy, Stephen, Hekmat-Nejad, Mohammad, Stuart, Darrin, McCormick, Frank and Nagel, Tobi (2013) RAF Inhibitors Activate the MAPK Pathway by Relieving Inhibitory Autophosphorylation. Cancer Cell, 23 (5). pp. 594-602. ISSN 1535-6108

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Hortobagyi, GN, Piccart-Gebhart, MJ, Rugo, HS, Burris, HA, Campone, M, Noguchi, S, Perez, AT, Deleu, I, Shtivelband, M, Provencher, L, Masuda, N, Dakhil, SR, Anderson, I, Chen, D, Damask, A, Huang, A, McDonald, R, Taran, T, Sahmoud, T and Baselga, J (2013) Correlation of molecular alterations with efficacy of everolimus in hormone-receptor-positive (HR+), HER2-negative advanced breast Cancer: Preliminary results from BOLERO-2. Journal of Clinical Oncology.

Hoyer, D, Durst, T, Fendt, M, Jacobson, LH, Betschart, C, Hintermann, S, Behnke, D, Cotesta, S, Laue, G, Ofner, S, Legangneux, E and Gee, CE (2013) Distinct effects of IPSU and suvorexant on mouse sleep architecture. Frontiers in Neuroscience. 235-.

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Huang, Zheng, Wu, Haiping, Chuai, Shannon, Xu, Fiona, Yan, Feng, Englund, Nathan, Wang, Zhaofu, Zhang, Hailong, Fang, Ming, Wang, Youzhen, Gu, Justin, Zhang, Maya, Yang, Teddy, Zhao, Kehao, Yu, Yanyan, Dai, Jingquan, Yi, Wei, Zhou, Shaolian, Li, Qian, Wu, Jing, Liu, Jun, Wu, Xu, Chan, Ho Man, Lu, Chris, Atadja, Peter, Li, En, Wang, Yan and Hu, Min (2013) The PHD domain targets NSD2 to oncogenic gene loci and drives tumorigenesis in multiple myeloma cells. Cancer Research, 73 (20). pp. 1-12.

Huebener, J, Weber, JJ, Richter, C, Honold, L, Weiss, A, Murad, F, Breuer, P, Wuellner, U, Bellstedt, P, Paquet-Durand, F, Takano, J, Saido, TC, Riess, O and Huu, PN (2013) Calpain-mediated ataxin-3 cleavage in the molecular pathogenesis of spinocerebellar ataxia type 3 (SCA3). HUMAN MOLECULAR GENETICS. pp. 508-518.

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Inta, D, Vogt, MA, Luoni, A, Filipovic, D, Lima-Ojeda, JM, Pfeiffer, N, Gasparini, F, Riva, MA and Gass, P (2013) Significant increase in anxiety during aging in mGlu5 receptor knockout mice. BEHAVIOURAL BRAIN RESEARCH. pp. 27-31.

Ioannou, Nikolaos, Seddon, Alan / M, Dalgleish, Angus, Mackintosh, David and Modjtahedi, Helmout (2013) Synergistic growth inhibition of human pancreatic cancer cells following treatment with a combination of ErbB family blocker afatinib and IGF-IR inhibitor NVP-AEW541. BMC Cancer, 13. pp. 41-52. ISSN 1471-2407

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Iwata, N, Sekiguchi, M, Hattori, Y, Takahashi, A, Asai, M, Ji, B, Higuchi, M, Staufenbiel, M, Muramatsu, S and Saido, TC (2013) Global brain delivery of neprilysin gene by intravascular administration of AAV vector in mice. Scientific Reports.

Jaguva Vasudevan, AA, Mario, P, Bulliard, Y, Cichutek, K, Trono, D, Haussinger, D and Munk, C (2013) Prototype foamy virus bet impairs the dimerization and cytosolic solubility of human APOBEC3G. Journal of Virology. pp. 9030-9040.

Jain, Rishi and Beckwith, Rohan (2013) Recent advances in small molecule target identification methods. Annual Reports in Medicinal Chemistry, 48. pp. 301-315. ISSN 0065-7743

Jakab, Annamaria, Winter, Serge, Raccuglia, Marc, Picard, Franck, Dumitras, Swati, Woessner, Ralph, Mistry, Sanket, Chudasama, Jayraj, Guttikar, Swati and Kretz, Olivier (2013) Validation of an LC-MS/MS method for the quantitative determination of Mavoglurant (AFQ056) in human plasma. Analytical and Bioanalytical Chemistry, 405 (1). pp. 215-223. ISSN 1618-2642

Jalili, Ahmed, Mertz, Kirsten D, Romanov, Julia, Wagner, Christine, Kalthoff, Frank, Stuetz, Anton, Pathria, Gaurav, Gschaider, Melanie, Stingl, Georg and Wagner, Stephan N (2013) NVP-LDE225, a potent and selective smoothened antagonist possess anti-melanoma activity both in vitro and in vivo. PLoS One, 8 (7). pp. 1-10.

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Javaid, S, Zhang, J, Anderssen, E, Black, JC, Wittner, BS, Tajima, K, Ting, DT, Smolen, GA, Zubrowski, M, Desai, R, Maheswaran, S, Ramaswamy, S, Whetstine, JR and Haber, DA (2013) Dynamic chromatin modification sustains epithelial-mesenchymal transition following inducible expression of snail-1. Cell Reports. pp. 1679-1689.

Jenkins, JL (2013) DRUG DISCOVERY Rethinking cellular drug response. NATURE CHEMICAL BIOLOGY. pp. 669-670.

Jimenez-Guri, E, Huerta-Cepas, J, Cozzuto, L, Wotton, KR, Kang, H, Himmelbauer, H, Roma, G, Gabaldon, T and Jaeger, J (2013) Comparative transcriptomics of early dipteran development. BMC Genomics.

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Kaendler, Kerstin, Warren, Andrew Paul, Lloyd, Peter, Sims, Jennifer and Sickert, Denise (2013) Evaluation of Dried Blood Spots for the Quantification of Therapeutic Monoclonal Antibodies and Detection of Anti-Drug Antibodies. Bioanalysis, 5 (5). pp. 613-622. ISSN 1757-6180

Kale, MG, Raichurkar, A, Shahul, HP, Waterson, D, McKinney, D, Manjunatha, MR, Kranthi, U, Koushik, K, Jena, LK, Shinde, V, Rudrapatna, S, Barde, S, Humnabadkar, V, Madhavapeddi, P, Basavarajappa, H, Ghosh, A, Ramya, V, Guptha, S, Sharma, S, Vachaspati, P, Kumar, KNM, Giridhar, J, Reddy, J, Panduga, V, Ganguly, S, Ahuja, V, Gaonkar, S, Kumar, CNN, Ogg, D, Tucker, JA, Boriack-Sjodin, PA, De Sousa, SM, Sambandamurthy, VK and Ghorpade, SR (2013) Thiazolopyridine ureas as novel antitubercular agents acting through inhibition of DNA gyrase B. Journal of Medicinal Chemistry. pp. 8834-8848.

Kalkeri, G, Lin, C, Gopilan, J, Sloan, K, Rijnbrand, R and Kwong, AD (2013) Restoration of the activated Rig-I pathway in hepatitis C virus (HCV) replicon cells by HCV protease, polymerase, and NS5A inhibitors in vitro at clinically relevant concentrations. Antimicrobial Agents and Chemotherapy. pp. 4417-4426.

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Kalliokoski, Tuomo, Kramer, Christian, Vulpetti, Anna and Gedeck, Peter (2013) Comparability of mixed IC50 data – A Statistical Analysis. PLOS ONE, 8 (4). e61007. ISSN 1932-6203

Kalliokoski, Tuomo, Olsson, Tjelvar and Vulpetti, Anna (2013) Sub-pocket analysis method for Fragment-Based Drug Discovery. Journal of Chemical Information and Modeling, 53 (1). pp. 131-141. ISSN 1549-9596

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Kammerer, M, Gutzwiller, S, Stauffer, D, Delhon, I, Seltenmeyer, Y and Fournier, B (2013) Estrogen Receptor alpha (ER alpha) and Estrogen Related Receptor alpha (ERR alpha) are both transcriptional regulators of the Runx2-I isoform. MOLECULAR AND CELLULAR ENDOCRINOLOGY. pp. 150-160.

Karkare, S, Chung, TTH, Collin, F, Mitchenall, LA, McKay, AR, Greive, SJ, Meyer, JJM, Lall, N and Maxwell, A (2013) The naphthoquinone diospyrin is an inhibitor of DNA gyrase with a novel mechanism of action. Journal of Biological Chemistry. pp. 5149-5156.

Kawanami, Toshio, Karns, Alexander, Adams, Christopher and Serrano-Wu, Michael (2013) Efficient preparation of Ellman’s imines from trifluoromethyl ketones promoted by zirconium tert-butoxide. Tetrahedron Letters.

Khokhlovich, Edward, Wahl, Daniel, Masiello, Anthony, Parisot, Pierre, Baumann, Stefan, Szustakowski, Joseph, Nirmala, Nanguneri and Tuch, David (2013) RAMP: A Bioinformatics Framework for Researching Imaging Agents through Molecular Pathways. Molecular Imaging, 12 (1). pp. 2-7. ISSN 1535-3508

Kim, H, Babu, CR and Burgess, DJ (2013) Quantification of protonation in organic solvents using solution NMR spectroscopy: Implication in salt formation. INTERNATIONAL JOURNAL OF PHARMACEUTICS. pp. 123-131.

Kim, SE, Patapoutian, A and Grandl, J (2013) Single Residues in the Outer Pore of TRPV1 and TRPV3 Have Temperature-Dependent Conformations. PLoS One.

Kim, SG, Hoffman, GR, Poulogiannis, G, Buel, GR, Jang, YJ, Lee, KW, Kim, B, Erikson, RL, Cantley, LC, Choo, AY and Blenis, J (2013) Metabolic Stress Controls mTORC1 Lysosomal Localization and Dimerization by Regulating the TTT-RUVBL1/2 Complex. MOLECULAR CELL. pp. 172-185.

Kim, Sunkyu, Caponigro, Giordano, Parasuraman, Sudha, Rader, JulieAnn, Maris, John, Russell, Mike, Hart, Lori, Nakazawa, Michael, Belcastro, Lili, Martinez, Daniel, Li, Yimei, Carpenter, Erica, Attiyeh, Edward, Schnepp, Robert, Wood, Andrew, Pawel, Bruce and Cole, Kristina (2013) Dual CDK4/CDK6 inhibition induces cell-cycle arrest and senescence in neuroblastoma. Clinical Cancer Research, 19 (22). pp. 6173-6182. ISSN 1078-0432

Kimmel, Dannielle W, Dole, William and Cliffel, David E (2013) Application of multianalyte microphysiometry to characterize macrophage metabolic responses to oxidized LDL and effects of an apoA-1 mimetic. Biochemical and Biophysical Research Communications, 431 (2). pp. 181-185. ISSN 0006291X

King, Daniel, Ma, Weilei, Yao, Danfeng and Tobias, Renee (2013) BLItz Application Note Instant Protein Analysis using BLItz for Faster, Easier Bioprocess Development and Production. Blitz Application Note.

Kinoshita, Katsuhiro, Aono, Yoshinori, Azuma, Momoyo, Kishi, Jun, Takezaki, Akio, Kishi, Masami, Makino, Hideki, Okazaki, Hiroyasu, Uehara, Hisanori, Izumi, Keisuke, Sone, Saburo and Nishioka, Yasuhiko (2013) Antifibrotic Effects of Focal Adhesion Kinase Inhibitor in Bleomycin-induced induced Pulmonary Fibrosis in Mice. American Journal of Respiratory Cell and Molecular Biology. ISSN 1044-1549

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Kondreddi, Ravinder Reddy, Jiricek, Jan, Rao, Srinivasa P.S., Lakshminarayana, Suresh Bangalore, Rao, Ranga Rao K.R., Herve, Maxime Marcel, Bifani, Juan Pablo, Kuhen, Kelli, Manjunatha, Ujjini Havaldar, Smith, Paul William, Camacho, Luis, Ma, Ida, Goh, Anne and Chatterjee, Arnab (2013) Design, synthesis and biological evaluation of indole-2-carboxamides, a promising class of anti-tuberculosis agents. J. med Chem, 56. pp. 8849-8859.

Koromilas, AE and Mounir, Z (2013) Control of oncogenesis by eIF2alpha phosphorylation: Implications in PTEN and PI3K-Akt signaling and tumor treatment. Future Oncology. pp. 1005-1015.

Korpal, Manav, Korn, Joshua, Ruddy, David, Doshi, Shivang, Yuan, Jing, Kim, Sunkyu, Cooke, Vesselina, Stegmeier, Frank, Roberts, Thomas, Sellers, William, Zhou, Wenlai and Zhu, Ping (2013) An F876l mutation in androgen receptor confers genetic and phenotypic resistance to MDV3100 (Enzalutamide). Cancer Discovery, 3 (9). pp. 1030-1043. ISSN 2159-8274

Kovarik, Jiri (2013) From Immunosuppression to Immunomodulation: Current Principles and Future Strategies. Pathobiology, 80 (6). pp. 275-281. ISSN PMID: 24013771

Kramer, Christian, Bereau, Tristan, Spinn, Alexander, Liedl, Klaus R., Gedeck, Peter and Meuwly, Markus (2013) Deriving Static Atomic Multipoles from the Electrostatic Potential. Journal of Chemical Information and Modeling, 53. pp. 3410-3417.

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Kustermann, S, Boess, F, Buness, A, Schmitz, M, Watzele, M, Weiser, T, Singer, T, Suter, L and Roth, A (2013) A label-free, impedance-based real time assay to identify drug-induced toxicities and differentiate cytostatic from cytotoxic effects. Toxicology in Vitro. pp. 1589-1595.

Kutchukian, Peter, Lindvall, Mika, Wright, Kirk, Ottl, Johannes, Jacob, Jaison, Scheufler, Clemens, Marzinzik, Andreas, Natasja, Brooijmans and Glick, Meir (2013) Beyond Consensus: Leveraging Inherent Biases in Fragment Based Screening Technologies. Journal of medicinal chemistry.

Lallifatidis, Georgios, Hoepfner, Dominic, Jaeg, Tiphaine, Guzman, Esther and Wright, Amy (2013) The Marine Natural Product Manzamine A targets Vacuolar ATPases and Autophagy in Pancreatic Cancer Cells. Marine Drugs, 12 (4). pp. 3500-3516. ISSN None

Lamacchia, C, Palmer, G, Rodriguez, E, Martin, P, Vigne, S, Seemayer, CA, Talabot-Ayer, D, Towne, JE and Gabay, C (2013) The severity of experimental arthritis is independent of IL-36 receptor signaling - art. no. R38. ARTHRITIS RESEARCH & THERAPY.

Laurent, Didier, Yerby, Brittany, Zhang, Bailin, Chen, Xiao-Hui, Gounarides, John, Gao, Jiaping and Duttaroy, Alokesh (2013) Hepatic glycogen cycling contributes to glucose lowering effects of the glucokinase activator LCZ960. European Journal Of Pharmacology, 715 (1-3). pp. 89-95.

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Leary, Beth A., Lawrence-Henderson, Rosemary, Mallozzi, Carolyn, Fernandez Ocana, Mireia, Duriga, Nicole, O'Hara, Denise, Kavosi, Mania, Qiang, Qu and Joyce, Alison (2013) Bioanalytical platform comparison using a generic human IgG PK assay format. Journal of Immunological Methods, 397 (1-2). pp. 28-36. ISSN 0022-1759

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Lee, ACY, Epe, C and Bowman, DD (2013) Comparison of Ancylostoma caninum worm counts acquired by endoscopy and necropsy. Veterinary Parasitology. pp. 538-540.

Lee, David and Andrade, Felipe (2013) Cytotoxic cells induce cellular hypercitrullination and citrullinated autoantigen production via perforin. Science Translational Medicine.

Lee, JH, Gao, J, Kosinski, PA, Elliman, SJ, Hughes, TE, Gromada, J and Kemp, DM (2013) Heat shock protein 90 (HSP90) inhibitors activate the heat shock factor 1 (HSF1) stress response pathway and improve glucose regulation in diabetic mice. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. pp. 1109-1113.

Leeds, Jennifer, Sachdeva, Meena, Mullin, Steve, Barnes, Whitney and Ruzin, Alexey (2013) In vitro selection, via serial passage, of Clostridium difficile mutants with reduced susceptibility to fidaxomicin or vancomycin. Journal of Antimicrobial Chemotherapy. ISSN 0305-7453

Lefevre, Gilbert, Bhad, Prafulla, Jain, Jay Prakash, Kalluri, Sampath, Cheng, Yi, Dave, Hardik and Stein, Daniel (2013) Evaluation of two novel tablet formulations of artemether-lumefantrine (Coartem®) for bioequivalence in a randomized, open-label, two-period study. Malaria Journal, 12 (1). p. 312. ISSN 1475-2875

Leino, MS, Loxham, M, Blume, C, Swindle, EJ, Jayasekera, NP, Dennison, PW, Shamji, BWH, Edwards, MJ, Holgate, ST, Howarth, PH and Davies, DE (2013) Barrier Disrupting Effects of Alternaria Alternata Extract on Bronchial Epithelium from Asthmatic Donors. PLoS One.

Lemmerer, Martin, London, Anne, Pannicucci, Alexandra, Gutierrez-Vargas, Cristina and Lihon, Michael (2013) Coupled Affinity and Sizing Chromatography: A novel in-process analytical tool to measure titer and trend Fc-protein aggregation. Journal of Immunological Methods, 393 (1/2). pp. 81-85. ISSN 0022-1759

Lepist, EI, Damaraju, VL, Zhang, J, Gati, WP, Yao, SYM, Smith, KM, Karpinski, E, Young, JD, Leung, KH and Cass, CE (2013) Transport of A(1) Adenosine Receptor Agonist Tecadenoson by Human and Mouse Nucleoside Transporters: Evidence for Blood-Brain Barrier Transport by Murine Equilibrative Nucleoside Transporter 1 mENT1. DRUG METABOLISM AND DISPOSITION. pp. 916-922.

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Lex, Alexander, Partl, Christian, Kalkofen, Denis, Streit, Marc, Gratzl, Samuel, Wassermann, Anne, Schmalstieg, Dieter and Pfister, Hanspeter (2013) Entourage: Visualizing Relationships between Biological Pathways using Contextual Subsets. IEEE Transactions on Visualization and Computer Graphics, 19 (12). pp. 2536-2545. ISSN 1077-2626

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Li, D, Jin, L, Alesi, GN, Kim, YM, Fan, J, Seo, JH, Wang, D, Tucker, M, Gu, TL, Lee, BH, Taunton, J, Magliocca, KR, Chen, ZG, Shin, DM, Khuri, FR and Kang, S (2013) The Prometastatic Ribosomal S6 Kinase 2-cAMP Response Element-binding Protein (RSK2-CREB) Signaling Pathway Up-regulates the Actin-binding Protein Fascin-1 to Promote Tumor Metastasis. JOURNAL OF BIOLOGICAL CHEMISTRY. pp. 32528-32538.

Li, Q, Korzan, WJ, Ferrero, DM, Chang, RB, Roy, DS, Buchi, M, Lemon, JK, Kaur, AW, Stowers, L, Fendt, M and Liberles, SD (2013) Synchronous Evolution of an Odor Biosynthesis Pathway and Behavioral Response. CURRENT BIOLOGY. pp. 11-20.

Li, Shi-Hua, Dong, Hongping, Li, Xiao-Feng, Xie, Xuping, Zhao, Hui, Deng, Yong-Qiang, Wang, Xiao-Yu, Ye, Qing, Zhu, Shun-Ya, Wang, Hong-Jiang, Zhang, Bo, Qin, E-De, Qin, Cheng-Feng and Shi, Pei-Yong (2013) Rational design of a flavivirus vaccine through abolishing viral RNA 2′-O methylation. Journal of virology, 87 (10). pp. 5812-5819. ISSN 1098-5514; 0022-538X

Li, Shu, Gu, Justin, Hao, Qin, Fan, Hong, Li, Ling, Zhou, Shaolian, Zhao, Kehao, Chan, Ho Man and Wang, Yingqi (2013) A liquid chromatography/mass spectrometry-based generic detection method for biochemical assay and hit discovery of histone methyltransferases. Analytical Biochemistry, 443 (2). pp. 214-221. ISSN 0003-2697

Li, Wenkui, Lin, Hui, Flarakos, Jimmy and Tse, Francis (2013) Practical Approaches to Incurred Sample LC-MS/MS Reanalysis: Confirming Unexpected Results. Analytical Chemistry.

Li, Y and Zhang, T (2013) Targeting cancer stem cells with sulforaphane, a dietary component from broccoli and broccoli sprouts. Future Oncology. pp. 1097-1103.

Li, ZZ, Gilbert, JA, Zhang, Y, Zhang, M, Qiu, Q, Ramanujan, K, Shavlakadze, T, Eash, JK, Scaramozza, A, Goddeeris, MM, Kirsch, DG, Campbell, KP, Brack, AS and Glass, DJ (2013) An HMGA2-IGF2BP2 Axis Regulates Myoblast Proliferation and Myogenesis (vol 23, pg 1176, 2012). Developmental Cell. p. 112.

Li, Zhizhong, Glass, David and Zhang, Yunyu (2013) The HMGA2-IGF2BP2 Pathway Maintains Controls Mutated N-Ras Levels in Rhabdomyosarcoma. Cancer Research.

Liang, Y, Quenelle, D, Vogel, JL, Mascaro, C, Ortega, A and Kristie, TM (2013) A novel selective LSD1/KDM1A inhibitor epigenetically blocks herpes simplex virus lytic replication and reactivation from latency. mBio.

Liao, Rijing, Wu, Haiping, Deng, Haibing, Yu, Yanyan, Hu, Min, Zhai, Huili, Yang, Pengyuan, Zhou, Shaolian and Yi, Wei (2013) Specific and Efficient N-propionylation of histones with Propionic acid N-hydroxysuccinimide Ester for Histone Marks Characterization by LC-MS. Analytical Chemistry, 85 (4). pp. 2253-2259. ISSN 0003-2700

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Pethe, Kevin, Jang, Jichan, Kang, Sunhee, Park, Seijin, Ahn, Sujin, Jiricek, Jan, Jung, Juyoung, Jeon, Hee Kyoung, Cechetto, Jonathan, Christophe, Thierry, Kempf, Marie, Jackson, Mary, Lenaerts, Anne J., Pham, Ha, Jones, Victoria, Seo, Min Jung, Lee, Saeyeon, Kim, Young, Seo, Mooyoung, Seo, Jeong Jea, Ko, Yoonae, Choi, Inhee, Kim, Ryangyeo, Kim, Seyeon, Lim, SeungBin, Yim, SeungAe, Jiyoun Nam, Jiyoun Nam, Hwankyu Kang, Hwankyu Kang, Chun-Taek Oh, Chun-Taek Oh, Yoojin Cho, Yoojin Cho, Yunhee Jang, Yunhee Jang, Junghwan Kim, Junghwan Kim, Chua, Adeline, Tan, Bee Huat, Nanjundappa, Mahesh Bangalore, Rao, Srinivasa P.S., Barnes, Whitney, Wintjens, René, Walker, John, Alonso, Sylvie, Kim, Jungjun, Oh, Soohyun, Oh, Taegwon, Han, Sung-Jun, No, Zaesung, Lee, Jinhwa, Brodin, Priscille, Cho, Sang-Nae, Nam, Kiyean, Bifani, Juan Pablo and Kim, Jaeseung (2013) Discovery of Q203, a potent clinical candidate for the treatment of tuberculosis. Nature Medicine, 19 (9). pp. 1157-1160. ISSN 1078-8956

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Phong, Wai Yee, Lin, WenWei, Rao, Srinivasa P.S., Dick, Thomas, Sylvie, Alonso and Pethe, Kevin (2013) Characterization of Phosphofructokinase Activity in Mycobacterium tuberculosis Reveals That a Functional Glycolytic Carbon Flow Is Necessary to Limit the Accumulation of Toxic Metabolic Intermediates under Hypoxia. PLOS One. ISSN 1932-6203

Pillai, Goonaseelan, Mirza, Fareed, Tadmor, Brigitta, Steimer, Jean-Louis, Davies, Geriant, Denti, Paolo, McIlleron, Helen and Holford, Nicholas H G (2013) Pharmacometrics – Opportunity for Reducing Disease Burden in the Developing World. Clinical Pharmacology and Therapeutics:Pharmacometrics & Systems Pharmacology, 2 (e69).

Pistorius, Dominik and Müller, Rolf (2013) Discovery of the rhizopodin biosynthetic gene cluster in Stigmatella aurantiaca Sg a15 by genome mining. ChemBioChem, 13 (3). pp. 416-426.

Poll, Chris, Verkuijl, Martin and Abbott Banner, Katharine (2013) Targeting TRP channels in airway disorders. Current Topics in Medicinal Chemistry, 13 (3). pp. 310-321. ISSN 1568-0266

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Radimerski, Thomas, Bentires-Alj, Mohamed and Britschgi, Adrian (2013) Targeting PI3K, IL-8/JAK2 axis and HER2 in metastatic breast cancer: which combination makes the whole greater than the sum of its parts. Drug Resist Update, 16 (3-5). pp. 68-72.

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Reilmann, Ralf, Saft, Carsten, Süssmuth, Sigurd, Priller, Joseph, Rosser, Anne, Rickards, Hugh, Schöls, Ludger, Pezous, Nicole, Landwehrmeyer,, Bernhard, Gomez-Mancilla, Baltazar, Rouzade-Dominguez, Marie-Laure, Gasparini, Fabrizio and Johns, Donald (2013) Efficacy, Safety and Tolerability of AFQ056 for the treatment of chorea in patients with Huntington’s disease. Movement DIsorders.

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Rice, DS (2013) Excitatory superficial dorsal horn interneurons are functionally heterogeneous and required for the full behavioral expression of Pain and Itch. Neuron, 78 (2). pp. 312-324. ISSN 0896-6273

Richie, Daryl, Thompson, Katherine, Studer, Christian, Aust, Thomas, Riedl, Ralph, Estoppey, David, Zabawa, Thomas, Drumm Iii, Joseph, Cotesta, Simona, Eichenberger, Juerg, Schuierer, Sven, Hartmann, Nicole, Movva, Rao, Tallarico, John, Ryder, Neil and Hoepfner, Dominic (2013) Identification and Evaluation of Novel Acetolactate Synthase Inhibitors as Antifungal Agents. Antimicrobial Agents and Chemotherapy, 57 (5). pp. 2272-2280. ISSN 0066-4804

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Riniker, Sereina and Landrum, Gregory (2013) Similarity maps - a visualization strategy for molecular fingerprints and machine-learning methods. Journal of Cheminformatics, 5. p. 43.

Ritter Iii, Robert, Senchyna, Michelle, Srinivasan, Sruthi, Heynen, Miriam L., Martell, Elizabeth and Jones1, Lyndon (2013) Expression of MUC1 and MUC16 in tears and conjunctival epithelial cells collected from postmenopausal women. Molecular Vision, 19. pp. 970-979.

Rombach-Riegraf, Verena, Karle, Anette, Wolf, Babette, Sorde, Laetitia, Koepke, Stephan, Gottlieb, Sascha, Djidja, Marie-Claude, Baban, Aida, Spindeldreher, Sebastian, Koulov, Atanas and Kiessling, Andrea (2013) Aggregation of Human Recombinant Monoclonal Antibodies Influences the Capacity of Dendritic Cells to Stimulate Adaptive T-cell Responses In Vitro. PLoS One.

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Rueeger, Heinrich, Lueoend, Rainer Martin, Machauer, Rainer, Veenstra, Siem, Jacobson, Laura, Staufenbiel, Matthias, Desrayaud, Sandrine, Rondeau, Jean-Michel, Moebitz, Henrik and Neumann, Ulf (2013) Discovery of Cyclic Sulfoxide Hydroxyethylamines as Potent and Selective β-Site APP-Cleaving Enzyme 1 (BACE1) Inhibitors: Structure Based Design and in Vivo Reduction of Amyloid β-Peptides. Bioorganic & Medicinal Chemistry Letters, 23. pp. 5300-5306.

Ruffner, Heinz (2013) Master thesis: Study of the Yap-Hippo and Wnt Pathways for Intestinal Regeneration in an Ex Vivo Small Intestinal 3D Organoid Model. Hochschule Mannheim. Master thesis, not published, presented to supervisor at Hochschule Mannheim under CDA..

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Shcheglovitov, A, Shcheglovitova, O, Yazawa, M, Portmann, T, Shu, R, Sebastiano, V, Krawisz, A, Froehlich, W, Bernstein, JA, Hallmayer, JF and Dolmetsch, RE (2013) SHANK3 and IGF1 restore synaptic deficits in neurons from 22q13 deletion syndrome patients. NATURE. pp. 267-271.

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Shieh, Mae Mae Yi Fong, Thompson, Corinne, My, Phan Vu Tra, Van, Thi Thuy Linh, Tediosi, Fabrizio, Merson, Laura, Farrar, Jeremy, Ha, Manh Tuan, Ho, Lu Viet, Pham, Thi Ngoc Tuyet and Baker, Stephen (2013) Policy of free healthcare for children under six in Vietnam: assessment of its non-usage during hospitalization for diarrhea in Ho Chi Minh City. Tropical Medicine & International Health.

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Shinde, DD, Kim, H, Choi, J, Pan, W, Bae, SK, Yeo, C, Shon, J, Kim, D and Shin, JG (2013) Different effects of clopidogrel and clarithromycin on the enantioselective pharmacokinetics of sibutramine and its active metabolites in healthy subjects. Journal of Clinical Pharmacology. pp. 550-558.

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Zhang, X, Zhang, J, Bauer, A, Zhang, L, Selinger, DW, Lu, CX and ten Dijke, P (2013) Fine-tuning BMP7 signalling in adipogenesis by UBE2O/E2-230K-mediated monoubiquitination of SMAD6. EMBO JOURNAL. pp. 996-1007.

Zheng, Guishan, Schaefer, Michael and Karplus, Martin (2013) Hemoglobin Bohr Effects: Analysis of the Histidine Residue Contributions. Biochemistry.

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Zhuang, G, Schmidt, M, Yao, J, Wu, X, Kaminker, JS, Jurinka, SS, Kolumam, G, Chung, AS, Jubb, A, Modrusan, Z, Ozawa, T, James, CD, Phillips, H, Haley, B, Tam, RNW, Clermont, AC, Cheng, JH, Yang, SX, Swain, SM, Chen, D, Scherer, SJ, Koeppen, H, Yeh, RF, Yue, P, Stephan, JP, Hegde, P, Ferrara, N, Singh, M and Bais, C (2013) Identification and Analysis of In Vivo VEGF Downstream Markers Link VEGF Pathway Activity with Efficacy of Anti-VEGF Therapies. CLINICAL CANCER RESEARCH. pp. 3681-3692.

Zimmerlin, Alfred Gilbert and Kiffe, Michael (2013) Fixing clearance as early as lead optimization using high throughput in-vitro incubations in combination with exact mass detection and automatic structure elucidation of metabolites. Drug Discovery Today, 10 (1). d191-E198. ISSN 1740-6749

Zitzmann, Kathrin, Vlotides, Galina Ailer and Auernhammer, Christoph J (2013) Potent antitumor activity of novel HSP90 inhibitors AUY922 and HSP990 in neuroendocrine carcinoid cells. International Journal of Oncology, 43 (6). pp. 1824-1832. ISSN 1791-2423

Züst, Roland, Dong, Hongping, Li, Xiao-Feng, Chang, David, Zhang, Bo, Jiang, Tao, Li, Shi-Hua, Deng, Yong-Qiang, Ellis, Brett R, Ellis, Esther M, Qin, Cheng-Feng, Shi, Pei-Yong and Fink, Katja (2013) Rational Design of a Live Attenuated Dengue Vaccine: 2′-O-Methyltransferase Mutants Are Highly Attenuated and Immunogenic in Mice and Macaques. PLoS Pathogens, 9 (8). ISSN 1553-7366

d'Offay, JM, Eberle, R, Wolf, RF, Kosanke, SD, Doocy, KR, Ayalew, S, Mansfeild, KG and White, GL (2013) Simian T-lymphotropic Virus-Associated Lymphoma in 2 Naturally Infected Baboons: T-cell Clonal Expansion and Immune Response during Tumor Development. COMPARATIVE MEDICINE. pp. 288-294.

de Lichtervelde, L, Boitano, AE, Wang, Y, Krastel, P, Petersen, F, Cooke, MP and Schultz, PG (2013) Eupalinilide E Inhibits Erythropoiesis and Promotes the Expansion of Hematopoietic Progenitor Cells. ACS CHEMICAL BIOLOGY. pp. 866-870.

fu, jun, koul, dimpy, wang, shuzhen, yao, jun, yuan, yin, sulman, erik p., lang, frederick f. and yung, alfred w.k. (2013) A Novel HSP90 inhibitor, NVP-HSP990 Targets the Cell Cycle Regulators to Produce Anti-glioma Effect in Olig2-expressing Glioma Stem Cells. Cancer Research, 73 (10). pp. 3062-3074.

fu, wei, chu, baoky and pledger, w.jack (2013) Apoptosis of osteosarcoma cultures by the combination of the cyclin-dependent kinase inhibitor SCH 727965 and a heat shock protein 90 inhibitor. Cell Death and Disease, 4 (3). ISSN 2041-4889

gillis, j and butler, L (2013) Constitutively-active androgen receptor variants function independently of the HSP90 chaperone but do not confer resistance to HSP90 inhibitors. Oncotarget, 4 (5). pp. 691-704. ISSN 1949-2553

infante, J, gerecitano, G, Chugh , r, cassier , P, ribrag, V, shapiro, G, witteveen, E, Matano, Alessandro, Chakraborty, Abhijit and Parasuraman, Sudha (2013) Phase 1 multicenter, open label, dose-escalation study of LEE011, an oral inhibitor of cyclin-dependent kinase 4/6, in patients with advanced solid tumors or lymphomas. Molecular Cancer Therapeutics, 12 (11). ISSN 1535-7163

kittan, nicolai, allen, ronald, dhaliwal, abhay, cavassani, karen, schaller, matthew, Jarai, Gabor, Westwick, John, kunkel, steven and hogaboam, cory (2013) Cytokine Induced Phenotypic and Epigenetic Signatures Are Key to Establishing Specific Macrophage Phenotypes. PLoS ONE, 8 (10). ISSN 1932-6203

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