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Analysis of the scientific competency questions followed by the IMI OpenPHACTS consortium for the development of the semantic web-based molecular information system OPS

Azzaoui, Kamal and Jacoby, Edgar and Senger, Stefan and Cuadrado Rodríguez, Emiliano and Loza, Mabel and Zdrazil, Barbara and Pinto, Marta and Williams, Antony J and de la Torre, Victor and Mestres, Jordi and Taboureau, Olivier and Rarey, Matthias and Ecker, Gerhard F (2013) Analysis of the scientific competency questions followed by the IMI OpenPHACTS consortium for the development of the semantic web-based molecular information system OPS. Drug Discovery Today, 18 (17-18). pp. 843-852. ISSN 1878-5832

Abstract

Molecular information systems play an important role in modern data-driven drug discovery. They do not only support decision making but also enable new discoveries via association and inference. Herein we outline the scientific requirements followed by the IMI Open PHACTS consortium for the design of the OPS information system built on the integration of compound-target-pathway-disease/phenotype data. Typical scientific competency questions provided by the consortium members will be analyzed based on the underlying data concepts and data associations needed to answer the questions. Publicly available data sources will be listed and the need and potential of semantic web-based technology will be presented.

Item Type: Article
Keywords: OPS IMI data research question
Date Deposited: 26 Apr 2016 23:46
Last Modified: 26 Apr 2016 23:46
URI: https://oak.novartis.com/id/eprint/7268

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