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Fluorescence Lifetime Assays

Cotton, Graham and Bowen, Wayne and Grundy, Robert and Hassiepen, Ulrich (2013) Fluorescence Lifetime Assays. Drug Discovery World.

Abstract

The benefits of fluorescence lifetime- (FLT-) based technologies have been highlighted for over a decade but thus far they have failed to gain widespread acceptance. Significant improvements in assay reagents and availability of HTS-compatible readers, however, have now delivered a cost-effective, robust technology applicable to broad range of therapeutic targets. This article charts FLT development to a highly attractive tool for drug discovery.

Item Type: Article
Keywords: assay, inhibitor, compound profiling, fluorescence lifetime, compound interference, screening
Date Deposited: 26 Apr 2016 23:46
Last Modified: 06 Jul 2016 23:45
URI: https://oak.novartis.com/id/eprint/11326

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