Items where Year is 2008

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Number of items: 382.

Article

Abdulla, Salim, Sagara, Issaka, Borrmann, Steffen, D'Alessandro, Umberto, González, Raquel, Hamel, Mary, Ogutu, Bernhards, Mårtensson, Andreas, Lyimo, John, Maiga, Hamma, Sasi, Philip, Nahum, Alain, Bassat, Quique, Juma, Elizabeth, Otieno, Lucas, Björkman, Anders, Beck, Hans Peter, Andriano, Kim, Cousin, Marc, Lefevre, Gilbert, Ubben, David and Premji, Zulfikarali (2008) Efficacy and safety of artemether-lumefantrine dispersible tablets compared with crushed commercial tablets in African infants and children with uncomplicated malaria: a randomised, single-blind, multicentre trial. Lancet, 372 (9652). pp. 1819-1827. ISSN 1474-547X

Abramowski, Dorothee, Wiederhold, Karl-Heinz, Furrer, Ulrich, Jaton, Anne-Lise, Neuenschwander, Anton, Runser, Marie-Josephine, Danner, Simone, Reichwald, Julia, Ammaturo, Domenico, Staab, Dieter, Stoeckli, Markus, Rueeger, Heinrich, Neumann, Ulf and Staufenbiel, Matthias (2008) Dynamics of Abeta turnover and deposition in different beta-amyloid precursor protein transgenic mouse models following gamma-secretase inhibition. The Journal of Pharmacology and Experimental Therapeutics, 327 (2). pp. 411-424. ISSN 1521-0103

Abudalu, Mohammed, Tyring, Stephen, Koltun, William, Bodsworth, Neil and Hamed, Kamal (2008) Single-day, patient-initiated famciclovir therapy versus 3-day valacyclovir regimen for recurrent genital herpes: a randomized, double-blind, comparative trial. Clinical Infectious Diseases : an official publication of the Infectious Diseases Society of America, 47 (5). pp. 651-658. ISSN 1537-6591

Almeida, M. Q., Fragoso, M. C. B. V., Lotfi, C. F. P., Santos, M. G., Nishi, M. Y., Costa, M. H. S., Lerario, A. M., Maciel, C. C., Mattos, G. E., Jorge, A. A. L., Mendonca, B. B. and Latronico, A. C. (2008) Expression of Insulin-Like Growth Factor-II and Its Receptor in Pediatric and Adult Adrenocortical Tumors. Journal of Clinical Endocrinology & Metabolism, 93 (9). pp. 3524-3531. ISSN 0021-972X

Alten, Rieke, Gram, Hermann, Joosten, Leo A, van den Berg, Wim B, Sieper, Joachim, Wassenberg, Siegfrid, Burmester, Gerd, van Riel, Piet, Diaz-Lorente, Maria, Bruin, Gerardus, Woodworth, Thasia G., Rordorf, Christiane, Batard, Yannick, Wright, Andrew and Jung, Thomas (2008) The human anti-IL-1 beta monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis. Arthritis research & therapy, 10 (3). R67. ISSN 1478-6362

Alten, Rieke, Gram, Hermann, Joosten, Leo, Berg, Wim, Sieper, Joachim, Wassenberg, Siegfrid, Burmester, Gerd, van Riel, Piet, Diaz-Lorente, Maria, Bruin, Gerardus, Woodworth, Thasia G., Rordorf, Christiane, Batard, Yannick, Wright, Andrew and Jung, Thomas (2008) The human anti-IL-1ß monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis. Arthritis Research & Therapy, 10 (3). R67. ISSN 1478-6354

Alvarez, Carlos (2008) On the origins of arrestin and rhodopsin. BMC Evolutionary Biology, 8 (1). p. 222. ISSN 1471-2148

Andreae, Marc, Steiner, Thomas, Hueber, Matthieu, Schopfer, Ulrich, Smith, Robert, Igo, Debra, Cantrell, Daryl, Hohos, Aaron and Kiwanuka, Andrew (2008) Closing the gap between centralized and decentralized compound management approaches. Combinatorial Chemistry & High Throughput Screening, 11 (10). pp. 825-833. ISSN 1386-2073

Atadja, Peter, Shao, Wenlin, Wang, Y, Growney, Joseph, Feng, Y, Yao, Yao, Wallace, A, Crisanti, C, Fawell, Stephen and Albelda, S (2008) Efficacy of panobinostat (LBH589) in lung cancer: potent anticancer activity in both in vitro and in vivo tumor models. European Journal of Cancer Supplements, 6 (12). pp. 48-49.

Ayalasomayajula, Surya, Tchaloyan, Stephanie, Yeh, Ching-Ming, Bizot, Marie-Noelle, Dieterich, Hans Armin, Howard, Danny and Dole, William (2008) A study of the pharmacokinetic interactions of the direct renin inhibitor aliskiren with allopurinol, celecoxib and cimetidine in healthy subjects. Current Medical Research and Opinion, 24 (3). pp. 717-726. ISSN 1473-4877

Ayalasomayajula, Surya, Yeh, Ching-Ming, Vaidyanathan, Sujata, Flannery, Brian, Dieterich, Hans Armin, Howard, Danny, Bedigian, Martin and Dole, William (2008) Effects of aliskiren, a direct Renin inhibitor, on cardiac repolarization and conduction in healthy subjects. Journal of Clinical Pharmacology, 48 (7). pp. 799-811. ISSN 0091-2700

Bagnoli, Fabio, Moschioni, Monica, Donati, Claudio, Dimitrovska, Valentina, Ferlenghi, Ilaria, Facciotti, Claudia, Muzzi, Alessandro, Giusti, Fabiola, Emolo, Carla, Sinisi, Antonella, Hilleringmann, Markus, Pansegrau, Werner, Censini, Stefano, Rappuoli, Rino, Covacci, Antonello, Masignani, Vega and Barocchi, Michele A (2008) A second pilus type in Streptococcus pneumoniae is prevalent in emerging serotypes and mediates adhesion to host cells. Journal of Bacteriology, 190 (15). pp. 5480-5492. ISSN 1098-5530

Bardotti, Angela, Averani, Giovanni, Berti, Francesco, Berti, Stefania, Carinci, Valeria, D'Ascenzi, Sandro, Fabbri, Barbara, Giannini, Sara, Giannozzi, Aldo, Magagnoli, Claudia, Proietti, Daniela, Norelli, Francesco, Rappuoli, Rino, Ricci, Stefano and Costantino, Paolo (2008) Physicochemical characterisation of glycoconjugate vaccines for prevention of meningococcal diseases. Vaccine, 26 (18). pp. 2284-2296. ISSN 0264-410X

Barlaskar, F. M., Spalding, A. C., Heaton, J. H., Kuick, R., Kim, A. C., Thomas, D. G., Giordano, T. J., Ben-Josef, E. and Hammer, G. D. (2008) Preclinical Targeting of the Type I Insulin-Like Growth Factor Receptor in Adrenocortical Carcinoma. Journal of Clinical Endocrinology & Metabolism, 94 (1). pp. 204-212. ISSN 0021-972X

Bartholomaus, I, Schlager, C, Brinkmann, Volker, Wekerle, H and Flugel, A (2008) Intravital 2-photon imaging of encephalitogenic effector cells during fingolimod (FTY720) treatment of experimental autoimmune encephalomyelitis. Multiple Sclerosis, 14 (No 1 Supplement). S30-S31.

Beaud, Marie-Laure, Schmidlin, Eric, Wannier, Thierry, Freund, Patrick, Bloch, Jocelyne, Mir, Anis, Schwab, Martin E and Rouiller, Eric M (2008) Anti-Nogo-A antibody treatment does not prevent cell body shrinkage in the motor cortex in adult monkeys subjected to unilateral cervical cord lesion. BMC neuroscience, 9 (5). ISSN 1471-2202

Beierle, Elizabeth A, Trujillo, Angelica, Nagaram, Abhilasha, Golubovskaya, Vita M, Cance, William G and Kurenova, Elena V (2008) TAE226 inhibits human neuroblastoma cell survival. Cancer Investigation, 26 (2). pp. 145-151. ISSN 1532-4192

Bell, Leslie, Bickford, Shari, Nguyen, Phong, Wang, Jianling, He, Timothy, Zhang, Bailin, Friche, Yannick, Zimmerlin, Alfred Gilbert, Urban, Laszlo and Bojanic, Dejan (2008) Evaluation of fluorescence- and mass spectrometry-based CYP inhibition assays for use in drug discovery. Journal of Biomolecular Screening : the official journal of the Society for Biomolecular Screening, 13 (5). pp. 343-353. ISSN 1087-0571

Bender, Andreas, Bojanic, Dejan, Davies, John, Crisman, Thomas, Mikhailov, Dmitri, Scheiber, Josef, Jenkins, Jeremy, Deng, Zhan, Hill, William, Popov, Maxim, Jacoby, Edgar and Glick, Meir (2008) Which aspects of HTS are empirically correlated with downstream success? Current Opinion in Drug Discovery & Development, 11 (3). pp. 327-337. ISSN 1367-6733

Berglund, Ken, Schleich, Wolfram, Wang, Hong, Feng, Guoping, Hall, William C, Kuner, Thomas and Augustine, George J (2008) Imaging synaptic inhibition throughout the brain via genetically targeted Clomeleon. Brain Cell Biology, 36 (1-4). pp. 101-118. ISSN 1559-7113

Bergstroem, Mats, Monazzam, Azita, Razifar, Pasha, Ide, Susan, Josephsson, Raymond and Langstrom, Bengt (2008) Modeling spheroid growth, PET tracer uptake, and treatment effects of the Hsp90 inhibitor NVP-AUY922. Journal of Nuclear Medicine: official publication, Society of Nuclear Medicine, 49 (7). pp. 1204-1210. ISSN 0161-5505

Bingel-Erlenmeyer, Rouven, Kohler, Rebecca, Kramer, Guenter, Sandikci, Arzu, Antolic, Snjezana, Maier, Timm, Schaffitzel, Christiane, Wiedmann, Brigitte, Bukau, Bernd and Ban, Nenad (2008) A peptide deformylase-ribosome complex reveals mechanism of nascent chain processing. Nature, 452 (7183). pp. 108-111. ISSN 1476-4687

Bingel-Erlenmeyer, Rouven, Kohler, Rebecca, Kramer, Günter, Sandikci, Arzu, Antolić, Snjezana, Maier, Timm, Schaffitzel, Christiane, Wiedmann, Brigitte, Bukau, Bernd and Ban, Nenad (2008) A peptide deformylase-ribosome complex reveals mechanism of nascent chain processing. Nature, 452 (7183). pp. 108-111. ISSN 1476-4687

Biron, Eric, Chatterjee, Jayanta, Ovadia, Oded, Langenegger, Daniel, Brueggen, Josef, Hoyer, Daniel, Schmid, Herbert, Jelinek, Raz, Gilon, Chaim, Hoffman, Amnon and Kessler, Horst (2008) Improving oral bioavailability of peptides by multiple N-methylation: somatostatin analogues. Angewandte Chemie (International ed. in English), 47 (14). pp. 2595-2599. ISSN 1521-3773

Bissiere, Stephanie, Plachta, Nicolas, Hoyer, Daniel, Mcallister, Kevin, Olpe, Hans-Rudolf, Grace, Anthony and Cryan, John F. (2008) The rostral anterior cingulate cortex modulates the efficiency of amygdala-dependent fear learning. Biological Psychiatry, 63 (9). pp. 821-831. ISSN 1873-2402

Blancafort, Pilar, Tschan, Mario P, Bergquist, Sharon, Guthy, Daniel Alexander, Brachat, Arndt Holger, Sheeter, Dennis A, Torbett, Bruce E, Erdmann, Dirk and Barbas, Carlos F (2008) Modulation of drug resistance by artificial transcription factors. Molecular Cancer Therapeutics, 7 (3). pp. 688-697. ISSN 1535-7163

Blanchard Rohner, Geraldine, Snape, Matthew D, Kelly, Dominic F, John, Tessa, Morant, Anita, Yu, Ly-Mee, Borkowski, Astrid, Ceddia, Francesca, Borrow, Ray, Siegrist, Claire-Anne and Pollard, Andrew J (2008) The magnitude of the antibody and memory B cell responses during priming with a protein-polysaccharide conjugate vaccine in human infants is associated with the persistence of antibody and the intensity of booster response. Journal of Immunology (Baltimore, Md. : 1950), 180 (4). pp. 2165-2173. ISSN 0022-1767

Blanchard Rohner, Geraldine, Snape, Matthew D, Kelly, Dominic F, John, Tessa, Morant, Anita, Yu, Ly-Mee, Borkowski, Astrid, Ceddia, Francesca, Borrow, Ray, Siegrist, Claire-Anne and Pollard, Andrew J (2008) The magnitude of the antibody and memory B cell responses during priming with a protein-polysaccharide conjugate vaccine in human infants is associated with the persistence of antibody and the intensity of booster response. The Journal of immunology : official journal of the American Association of Immunologists, 180 (4). pp. 2165-2173. ISSN 0022-1767

Ble, Francois-Xavier, Cannet, Catherine, Zurbruegg, Stefan, Karmouty Quintana, Harry, Bergmann, Reinhard, Frossard, Nelly, Trifilieff, Alexandre and Beckmann, Nicolau (2008) Allergen-induced lung inflammation in actively sensitized mice assessed with MR imaging. Radiology, 248 (3). pp. 834-843. ISSN 1527-1315

Boath, Alistair, Graf, Christine, Lidome, Emilie, Ullrich, Thomas, Nussbaumer, Peter and Bornancin, Frederic (2008) Regulation and traffic of ceramide 1-phosphate produced by ceramide kinase: comparative analysis to glucosylceramide and sphingomyelin. The Journal of Biological Chemistry, 283 (13). pp. 8517-8526. ISSN 0021-9258

Boehme, J, Suttorp, M, Fischer, R, Bornhaeuser, M and Gasser, Juerg Andreas (2008) Influence of Imatinib on Bone Remodeling in Juvenile Mice. Journal of Bone and Mineral Research, 23. S189.

Bowen, David G, Shoukry, Naglaa H, Grakoui, Arash, Fuller, Michael J, Cawthon, Andrew G, Dong, Christine, Hasselschwert, Dana L, Brasky, Kathleen M, Freeman, Gordon J, Seth, Nilufer P, Wucherpfennig, Kai W, Houghton, Mortimer and Walker, Christopher M (2008) Variable patterns of programmed death-1 expression on fully functional memory T cells after spontaneous resolution of hepatitis C virus infection. Journal of virology, 82 (10). pp. 5109-5114. ISSN 1098-5514

Breitling, Rainer, Li, Yang, Tesson, Bruno M, Fu, Jingyuan, Wu, Chunlei, Wiltshire, Tim, Gerrits, Alice, Bystrykh, Leonid V, de Haan, Gerald, Su, Andrew and Jansen, Ritsert C (2008) Genetical genomics: spotlight on QTL hotspots. PLoS Genetics, 4 (10). e1000232. ISSN 1553-7404

Broeker, Michael and Kollaritsch, Herwig (2008) After a tick bite in a tick-borne encephalitis virus endemic area: current positions about post-exposure treatment. Vaccine, 26 (7). pp. 863-868. ISSN 0264-410X

Brouwers, J E M, Lambers, F M, Gasser, Juerg Andreas, van Rietbergen, B and Huiskes, R (2008) Bone degeneration and recovery after early and late bisphosphonate treatment of ovariectomized wistar rats assessed by in vivo micro-computed tomography. Calcified Tissue International, 82 (3). pp. 202-211. ISSN 0171-967X

Brouwers, J E M, Lambers, F M, Gasser, Juerg Andreas, van Rietbergen, B and Huiskes, R (2008) Bone degeneration and recovery after early and late bisphosphonate treatment of ovariectomized wistar rats assessed by in vivo micro-computed tomography. Calcified tissue international, 82 (3). pp. 202-211. ISSN 0171-967X

Bruin, Gerardus, Faller, Thomas, Wiegand, Hansjoerg, Schweitzer, Alain, Nick, Hanspeter, Schneider, Josef, Boernsen, K. Olaf and Waldmeier, Felix (2008) Pharmacokinetics, distribution, metabolism, and excretion of deferasirox and its iron complex in rats. Drug metabolism and disposition: the biological fate of chemicals, 36 (12). pp. 2523-2538. ISSN 1521-009X

Bruin, Gerardus, Faller, Thomas, Wiegand, Hansjoerg, Schweitzer, Alain, Nick, Hanspeter, Schneider, Josef, Boernsen, K. Olaf and Waldmeier, Felix (2008) Pharmacokinetics, Distribution, Metabolism, and Excretion of Deferasirox and its Iron Complex in Rats. Drug Metabolism and Disposition, 36 (12). pp. 2523-2538. ISSN 1521-009X

Buechau, Amanda S, Schauber, Jürgen, Hultsch, Thomas, Stuetz, Anton and Gallo, Richard L (2008) Pimecrolimus enhances TLR2/6-induced expression of antimicrobial peptides in keratinocytes. The Journal of Investigative Dermatology, 128 (11). pp. 2646-2654. ISSN 1523-1747

CHANKVETADZE, Bezhan and Francotte, Eric (2008) Preface: Enantioseparations - Dedicated to Wolfgang Lindner. Journal of Chromatography B, 875 (1). p. 1. ISSN 15700232

Calvo, Jennifer, Daniels, Thomas, Wang, Xiaomei, Paul, Angelika, Lin, Jiandie, Spiegelman, Bruce M, Stevenson, Susan and Rangwala, Shamina (2008) Muscle-specific expression of PPARgamma coactivator-1alpha improves exercise performance and increases peak oxygen uptake. Journal of Applied Physiology (Bethesda, Md. : 1985), 104 (5). pp. 1304-1312. ISSN 8750-7587

Campa, Cristiana, Baiutti, Edi and Flamigni, Anna (2008) Capillary electrophoresis of sugar acids. Methods in Molecular Biology (Clifton, N.J.), 384. pp. 307-355. ISSN 1064-3745

Cao, Weihuan, Song, Ho-Juhn, Gangi, Tina, Kelkar, Anju, Antani, Isha, Garza, Dan and Konsolaki, Mary (2008) Identification of novel genes that modify phenotypes induced by Alzheimer's beta-amyloid overexpression in Drosophila. Genetics, 178 (3). pp. 1457-1471. ISSN 0016-6731

Caputo, Antonella, Brocca-Cofano, Egidio, Castaldello, Arianna, Voltan, Rebecca, Gavioli, Riccardo, Srivastava, Indresh K, Barnett, Susan W, Cafaro, Aurelio and Ensoli, Barbara (2008) Characterization of immune responses elicited in mice by intranasal co-immunization with HIV-1 Tat, gp140 DeltaV2Env and/or SIV Gag proteins and the nontoxicogenic heat-labile Escherichia coli enterotoxin. Vaccine, 26 (9). pp. 1214-1227. ISSN 0264-410X

Chen, Jian, Shi, Xiaoying, Padmanabhan, Ranjani, Wang, Qiong, Wu, Zhidan, Stevenson, Susan, Hild, Marc, Garza, Dan and Li, Hao (2008) Identification of novel modulators of mitochondrial function by a genome-wide RNAi screen in Drosophila melanogaster. Genome Research, 18 (1). pp. 123-136. ISSN 1088-9051

Chen, Yuefeng, Wei, Tao, Yan, Lei, Lawrence, Frank, Qian, Hui-Rong, Burkholder, Timothy P, Starling, James J, Yingling, Jonathan M and Shou, Jianyong (2008) Developing and applying a gene functional association network for anti-angiogenic kinase inhibitor activity assessment in an angiogenesis co-culture model. BMC Genomics, 9. p. 264. ISSN 1471-2164

Chene, Patrick (2008) Challenges in design of biochemical assays for the identification of small molecules to target multiple conformations of protein kinases. Drug Discovery Today, 13 (11-12). pp. 522-529. ISSN 1359-6446

Chene, Patrick (2008) PcrA/UvrD/Rep DNA helicases in bacterial genomes. Biochemical Systematics and Ecology, 36 (2). pp. 101-109. ISSN 0305-1978

Chesko, James, Kazzaz, Jina, Ugozzoli, Mildred, Singh, Manmohan, O'Hagan, Derek T, Madden, Claire, Perkins, Mark and Patel, Nikin (2008) Characterization of antigens adsorbed to anionic PLG microparticles by XPS and TOF-SIMS. Journal of Pharmaceutical Sciences, 97 (4). pp. 1443-1453. ISSN 0022-3549

Chiba, Hatsune, Hirasawa, Ryutaro, Kaneda, Masahiro, Amakawa, Yuko, Li, En, Sado, Takashi and Sasaki, Hiroyuki (2008) De novo DNA methylation independent establishment of maternal imprint on X chromosome in mouse oocytes. Genesis (New York, N.Y. : 2000), 46 (12). pp. 768-774. ISSN 1526-968X

Chung, Yuen-Li, Troy, Helen, Kristeleit, Rebecca, Aherne, Wynne, Jackson, L Elizabeth, Atadja, Peter, Griffiths, John R, Judson, Ian R, Workman, Paul, Leach, Martin O and Beloueche-Babari, Mounia (2008) Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of a novel histone deacetylase inhibitor, LAQ824, in human colon carcinoma cells and xenografts. Neoplasia (New York, N.Y.), 10 (4). pp. 303-313. ISSN 1476-5586

Coers, Jörn, Bernstein-Hanley, Isaac, Grotsky, David, Parvanova, Iana, Howard, Jonathan C, Taylor, Gregory A, Dietrich, William and Starnbach, Michael N (2008) Chlamydia muridarum evades growth restriction by the IFN-gamma-inducible host resistance factor Irgb10. Journal of Immunology (Baltimore, Md. : 1950), 180 (9). pp. 6237-6245. ISSN 0022-1767

Cooper, P J, Ayre, Gareth, Martin, Carmen, Rizzo, J A, Ponte, E V and Cruz, A A (2008) Geohelminth infections: a review of the role of IgE and assessment of potential risks of anti-IgE treatment. Allergy, 63 (4). pp. 409-417. ISSN 1398-9995

Coote, Kevin, Atherton, Hazel, Young, Alice, Sugar, Rosemary, Burrows, Rachel, Smith, Nicola, Schlaeppi, Jean-Marc, Groot-Kormelink, Paul, Gosling, Martin and Danahay, Henry (2008) The guinea-pig tracheal potential difference as an in vivo model for the study of epithelial sodium channel function in the airways. British Journal of Pharmacology, 155 (7). pp. 1025-1033. ISSN 1476-5381

Crisman, Thomas, Bender, Andreas, Milik, Mariusz, Jenkins, Jeremy, Scheiber, Josef, Sukuru, Sai Chetan, Fejzo, Jasna, Hommel, Ulrich, Davies, John and Glick, Meir (2008) "Virtual fragment linking": an approach to identify potent binders from low affinity fragment hits. Journal of Medicinal Chemistry, 51 (8). pp. 2481-2491. ISSN 0022-2623

Crooks, Emma T, Jiang, Pengfei, Franti, Michael, Wong, Sharon, Zwick, Michael B, Hoxie, James A, Robinson, James E, Moore, Penny L and Binley, James M (2008) Relationship of HIV-1 and SIV envelope glycoprotein trimer occupation and neutralization. Virology, 377 (2). pp. 364-378. ISSN 0042-6822

Cross, N C P, Daley, G Q, Green, A R, Hughes, T P, Jamieson, C, Manley, Paul W., Mughal, T, Perrotti, D, Radich, J, Skoda, R, Soverini, S, Vainchenker, W, Verstovsek, S, Villeval, J-L and Goldman, J M (2008) BCR-ABL1-positive CML and BCR-ABL1-negative chronic myeloproliferative disorders: some common and contrasting features. Leukemia : Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K, 22 (11). pp. 1975-1989. ISSN 1476-5551

Croyle, Michelle, Akeno, Nagako, Knauf, Jeffrey A, Fabbro, Doriano, Chen, Xu, Baumgartner, Jacqueline E, Lane, Heidi and Fagin, James A (2008) RET/PTC-induced cell growth is mediated in part by epidermal growth factor receptor (EGFR) activation: evidence for molecular and functional interactions between RET and EGFR. Cancer Research, 68 (11). pp. 4183-4191. ISSN 1538-7445

Cunningham, Matthew, Thomas, Hilary, Christopher, Marks, Margaret, Green, Zhen, Fan and Helmout, Modjtahedi (2008) Co-targeting the EGFR and IGF-IR with anti-EGFR monoclonal antibody ICR62 and the IGF-IR tyrosine kinase inhibitor NVP-AEW541 in colorectal cancer cells. International Journal of Oncology, 33 (5). pp. 1107-1113. ISSN 1019-6439

D'Eon, Tara, Pierce, Kerry, Roix, Jeffrey, Tyler, Andrew, Chen, Hong and Teixeira, Sandra (2008) The role of adipocyte insulin resistance in the pathogenesis of obesity-related elevations in endocannabinoids. Diabetes, 57 (5). pp. 1262-1268. ISSN 1939-327X

De Bruyne, Elke, Bos, Tomas Jan, Asosingh, Kewal, Vande Broek, Isabelle, Menu, Eline, Van Valckenborgh, Els, Atadja, Peter, Coiteux, Valérie, Leleu, Xavier, Thielemans, Kris, Van Camp, Ben, Vanderkerken, Karin and Van Riet, Ivan (2008) Epigenetic silencing of the tetraspanin CD9 during disease progression in multiple myeloma cells and correlation with survival. Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 14 (10). pp. 2918-2926. ISSN 1078-0432

Del Vecchio, Mariangela and Balducci, Enrico (2008) Mono ADP-ribosylation inhibitors prevent inflammatory cytokine release in alveolar epithelial cells. Molecular and Cellular Biochemistry, 310 (1-2). pp. 77-83. ISSN 0300-8177

Demuth, Andreas, Aharonowitz, Yair, Bachmann, Till T, Blum-Oehler, Gabriele, Buchrieser, Carmen, Covacci, Antonello, Dobrindt, Ulrich, Emody, Levente, van der Ende, Arie, Ewbank, Jonathan, Fernandez, Luis Angel, Frosch, Matthias, Garcia-Del Portillo, Francisco, Gilmore, Michael S, Glaser, Philippe, Goebel, Werner, Hasnain, Seyed E, Heesemann, Juergen, Islam, Khalid, Korhonen, Timo, Maiden, Martin, Meyer, Thomas F, Montecucco, Cesare, Oswald, Eric, Parkhill, Julian, Pucciarelli, M Graciela, Ron, Eliora, Svanborg, Catharina, Uhlin, Bernt Eric, Wai, Sun Nyunt, Wehland, Juergen and Hacker, Joerg (2008) Pathogenomics: an updated European Research Agenda. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and evolutionary genetics in infectious diseases, 8 (3). pp. 386-393. ISSN 1567-1348

Dodeller, Francis, Gottar-Guillier, Marie, Huesken, Dieter, Iourgenko, Vadim and Cenni, Bruno (2008) The lysosomal transmembrane protein 9B regulates the activity of inflammatory signaling pathways. The Journal of Biological Chemistry, 283 (31). pp. 21487-21494. ISSN 0021-9258

Ducray, Pierre, Gauvry, Noelle, Pautrat, Francois, Goebel, Thomas, Fruechtel, Joerg, Desaules, Yves, Schorderet Weber, Sandra, Bouvier, Jacques, Wagner, Beatrix, Froelich, Olivier and Kaminsky, Ronald (2008) Discovery of amino-acetonitrile derivatives, a new class of synthetic anthelmintic compounds. Bioorganic & Medicinal Chemistry Letters, 18 (9). pp. 2935-2938. ISSN 1464-3405

Dultz, Elisa, Hildenbeutel, Markus, Martoglio, Bruno, Hochman, Jacob, Dobberstein, Bernhard and Kapp, Katja (2008) The signal peptide of the mouse mammary tumor virus Rem protein is released from the endoplasmic reticulum membrane and accumulates in nucleoli. The Journal of Biological Chemistry, 283 (15). pp. 9966-9976. ISSN 0021-9258

Dunsmore, Colin J, Miller, Keith, Blake, Katy L, Patching, Simon G, Henderson, Peter J F, Garnett, James, Stubbings, William J, Phillips, Simon E V, Palestrant, Deborah, De Los Angeles, Joseph, Leeds, Jennifer, Chopra, Ian and Fishwick, Colin W G (2008) 2-Aminotetralones: novel inhibitors of MurA and MurZ. Bioorganic & Medicinal Chemistry Letters, 18 (5). pp. 1730-1734. ISSN 1464-3405

Dunsmore, Colin J, Miller, Keith, Blake, Katy L, Patching, Simon G, Henderson, Peter J F, Garnett, James A, Stubbings, William J, Phillips, Simon E V, Palestrant, Deborah J, Angeles, Joseph De Los, Leeds, Jennifer A, Chopra, Ian and Fishwick, Colin W G (2008) 2-Aminotetralones: novel inhibitors of MurA and MurZ. Bioorganic & medicinal chemistry letters, 18 (5). pp. 1730-1734. ISSN 1464-3405

Dutt, Amit, Salvesen, Helga B, Chen, Tzu-Hsiu, Ramos, Alex H, Onofrio, Robert C, Hatton, Charlie, Nicoletti, Richard, Winckler, Wendy, Grewal, Rupinder, Hanna, Megan, Wyhs, Nicolas, Ziaugra, Liuda, Richter, Daniel J, Trovik, Jone, Engelsen, Ingeborg B, Stefansson, Ingunn M, Fennell, Tim, Cibulskis, Kristian, Zody, Michael C, Akslen, Lars A, Gabriel, Stacey, Wong, Kwok-Kin, Sellers, William, Meyerson, Matthew and Greulich, Heidi (2008) Drug-sensitive FGFR2 mutations in endometrial carcinoma. Proceedings of the National Academy of Sciences of the United States of America, 105 (25). pp. 8713-8717. ISSN 1091-6490

Ece Gamsiz, D, Shah, Lipa, Devalapally, Harikrishna, Amiji, Mansoor M and Carrier, Rebecca L (2008) A model predicting delivery of saquinavir in nanoparticles to human monocyte/macrophage (Mo/Mac) cells. Biotechnology and Bioengineering, 101 (5). pp. 1072-1082. ISSN 1097-0290

Elis, Winfried, Triantafellow, Ellen, Wolters, Natalie M, Sian, Katie R, Caponigro, Giordano, Borawski, Jason, Gaither, Larry, Murphy, Leo, Finan, Peter and Mackeigan, Jeff (2008) Down-regulation of class II phosphoinositide 3-kinase alpha expression below a critical threshold induces apoptotic cell death. Molecular Cancer Research : MCR, 6 (4). pp. 614-623. ISSN 1541-7786

Endres, Thomas and Fendt, Markus (2008) Inactivation of the lateral septum blocks fox odor-induced fear behavior. Neuroreport, 19 (6). pp. 667-670. ISSN 0959-4965

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Fendt, Markus, Schmid, Susanne, Thakker, Deepak, Jacobson, Laura, Yamamoto, R, Mitsukawa, Kayo, Maier, Rainer, Natt, Francois, Huesken, Dieter, Kelly, Peter, Mcallister, Kevin, Hoyer, Daniel, Van Der Putten, P. Herman, Cryan, John F. and Flor, Peter Josef (2008) mGluR7 facilitates extinction of aversive memories and controls amygdala plasticity. Molecular Psychiatry, 13 (10). pp. 970-979. ISSN 1476-5578

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Friedrichs, N, Küchler, J, Endl, E, Koch, A, Czerwitzki, J, Wurst, P, Metzger, D, Schulte, JH, Holst, MI, Heukamp, LC, Larsson, O, Tanaka, S, Kawai, A, Wardelmann, E, Buettner, R, Pietsch, T and Hartmann, W (2008) Insulin-like growth factor-1 receptor acts as a growth regulator in synovial sarcoma. The Journal of Pathology, 216 (4). pp. 428-439. ISSN 0022-3417

Furet, Pascal, Caravatti, Giorgio, Guagnano, Vito, Lang, Marc, Meyer, Thomas and Schoepfer, Joseph (2008) Entry into a new class of protein kinase inhibitors by pseudo ring design. Bioorganic & Medicinal Chemistry Letters, 18 (3). pp. 897-900. ISSN 1464-3405

Galanello, Renzo, Piga, Antonio, Cappellini, Maria Domenica, Forni, Gian Luca, Zappu, Antonella, Origa, Raffaella, Dutreix, Catherine, Belleli, Rossella, Ford, John M, Rivière, Gilles-Jacques, Balez, Sébastien, Alberti, Daniele and Séchaud, Romain (2008) Effect of food, type of food, and time of food intake on deferasirox bioavailability: recommendations for an optimal deferasirox administration regimen. Journal of clinical pharmacology, 48 (4). pp. 428-435. ISSN 0091-2700

Galanello, Renzo, Piga, Antonio, Cappellini, Maria Domenica, Forni, Monique, Zappu, Antonella, Origa, Raffaella, Dutreix, Catherine, Belleli, Rossella, Ford, John Malcolm, Riviere, Gilles-Jacques, Balez, Sebastien, Alberti, Daniele Maria and Sechaud, Romain (2008) Effect of food, type of food, and time of food intake on deferasirox bioavailability: recommendations for an optimal deferasirox administration regimen. Journal of clinical pharmacology, 48 (4). pp. 428-435. ISSN 0091-2700

Ganapathipillai, Suganthini S, Medová, Michaela, Aebersold, Daniel M, Manley, Paul W., Berthou, Sylvie, Streit, Bruno, Blank-Liss, Wieslawa, Greiner, Richard H, Rothen-Rutishauser, Barbara and Zimmer, Yitzhak (2008) Coupling of mutated Met variants to DNA repair via Abl and Rad51. Cancer Research, 68 (14). pp. 5769-5777. ISSN 1538-7445

Gander, Stefan, Bonenfant, Debora, Altermatt, Patrick, Martin, Dietmar E, Hauri, Simon, Moes, Suzette, Hall, Michael N and Jenoe, Paul (2008) Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase. Rapid Communications in Mass Spectrometry : RCM, 22 (23). pp. 3743-3753. ISSN 0951-4198

Gao, Jinhai, Haas, Hansjoerg, Wang, Kate, Chen, Zhuoliang, Breitenstein, Werner and Rajan, Srinivasan (2008) The use of MPA amide for the assignment of absolute configuration of a sterically hindered cyclic secondary amine by 'mix and shake' NMR method. Magnetic Resonance in Chemistry : MRC, 46 (1). pp. 17-22. ISSN 1097-458X

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Gasser, Juerg Andreas, Ingold, Peter, Venturiere, Andrea, Shen, Victor and Green, Jonathan (2008) Long-term protective effects of zoledronic acid on cancellous and cortical bone in the ovariectomized rat. Journal of Bone and Mineral Research : the official journal of the American Society for Bone and Mineral Research, 23 (4). pp. 544-551. ISSN 1523-4681

Gedeck, Peter and Lewis, Richard (2008) Exploiting QSAR models in lead optimization. Current Opinion in Drug Discovery & Development, 11 (4). pp. 569-575. ISSN 1367-6733

Geisler, Jürgen, Helle, Hilgegunn, Ekse, Dagfinn, Duong, Nhat K, Evans, Dean Brent, Nordbø, Yngve, Aas, Turid and Lønning, Per E (2008) Letrozole is superior to anastrozole in suppressing breast cancer tissue and plasma estrogen levels. Clinical Cancer Research : an official journal of the American Association for Cancer Research, 14 (19). pp. 6330-6335. ISSN 1078-0432

Gengenbacher, Martin, Xu, Ting, Niyomrattanakit, Pornwaratt, Spraggon, Glen and Dick, Thomas (2008) Biochemical and structural characterization of the putative dihydropteroate synthase ortholog Rv1207 of Mycobacterium tuberculosis. FEMS Microbiology Letters, 287 (1). pp. 128-135. ISSN 0378-1097

Germain, Ronald N, Bajenoff, Marc, Castellino, Flora, Chieppa, Marcello, Egen, Jackson G, Huang, Alex Y C, Ishii, Masaru, Koo, Lily Y and Qi, Hai (2008) Making friends in out-of-the-way places: how cells of the immune system get together and how they conduct their business as revealed by intravital imaging. Immunological Reviews, 221. pp. 163-181. ISSN 1600-065X

Germain, Ronald N, Bajénoff, Marc, Castellino, Flora, Chieppa, Marcello, Egen, Jackson G, Huang, Alex Y C, Ishii, Masaru, Koo, Lily Y and Qi, Hai (2008) Making friends in out-of-the-way places: how cells of the immune system get together and how they conduct their business as revealed by intravital imaging. Immunological Reviews, 221. pp. 163-181. ISSN 1600-065X

Giannoni, Francesca, Shea, Ashley, Inglis, Chandra, Lee, Lian Ni and Sarawar, Sally R (2008) CD40 engagement on dendritic cells, but not on B or T cells, is required for long-term control of murine gammaherpesvirus 68. Journal of Virology, 82 (22). pp. 11016-11022. ISSN 1098-5514

Gillet, Ludovic, Namoto, Kenji, Ruchti, Alexandra, Hoving, Sjouke, Boesch, Danielle, Inverardi, Bruno, Mueller, Dieter, Coulot, Michele, Schindler, Patrick, Schweigler, Patrick, Bernardi, Anna and Gil Parrado, Shirley (2008) In-cell selectivity profiling of serine protease inhibitors by activity-based proteomics. Molecular & Cellular Proteomics : MCP, 7 (7). pp. 1241-1253. ISSN 1535-9484

Gillet, Ludovic, Namoto, Kenji, Ruchti, Alexandra, Hoving, Sjouke, Boesch, Danielle, Inverardi, Bruno, Mueller, Dieter, Coulot, Michele, Schindler, Patrick, Schweigler, Patrick, Bernardi, Anna and Gil-Parrado, Shirley (2008) In-cell selectivity profiling of serine protease inhibitors by activity-based proteomics. Molecular & Cellular Proteomics : MCP, 7 (7). pp. 1241-1253. ISSN 1535-9484

Gjoni, Tina and Urwyler, Stephan (2008) Receptor activation involving positive allosteric modulation, unlike full agonism, does not result in GABAB receptor desensitization. Neuropharmacology, 55 (8). pp. 1293-1299. ISSN 0028-3908

Glickman, Fraser, Schmid, Andres and Ferrand, Sandrine (2008) Scintillation proximity assays in high-throughput screening. Assay and Drug Development Technologies, 6 (3). pp. 433-455. ISSN 1540-658X

Goddyn, Hannelore, Callaerts-Vegh, Zsuzsanna, Stroobants, Stijn, Dirikx, Trinette, Vansteenwegen, Debora, Hermans, Dirk, Van Der Putten, P. Herman and D'Hooge, Rudi (2008) Deficits in acquisition and extinction of conditioned responses in mGluR7 knockout mice. Neurobiology of Learning and Memory, 90 (1). pp. 103-111. ISSN 1095-9564

Golks, Alexander and Guerini, Danilo (2008) The O-linked N-acetylglucosamine modification in cellular signalling and the immune system. 'Protein modifications: beyond the usual suspects' review series. EMBO Reports, 9 (8). pp. 748-753. ISSN 1469-3178

Golubovskaya, Vita M, Nyberg, Carl, Zheng, Min, Kweh, Frederick, Magis, Andrew, Ostrov, David and Cance, William G (2008) A small molecule inhibitor, 1,2,4,5-benzenetetraamine tetrahydrochloride, targeting the y397 site of focal adhesion kinase decreases tumor growth. Journal of Medicinal Chemistry, 51 (23). pp. 7405-7416. ISSN 1520-4804

Golubovskaya, Vita M, Virnig, Christopher and Cance, William G (2008) TAE226-induced apoptosis in breast cancer cells with overexpressed Src or EGFR. Molecular Carcinogenesis, 47 (3). pp. 222-234. ISSN 1098-2744

Goodship, Allen, Blunn, Gordon W, Green, Jonathan and Coathup, Melanie J (2008) Prevention of strain-related osteopenia in aseptic loosening of hip prostheses using perioperative bisphosphonate. Journal of Orthopaedic Research : official publication of the Orthopaedic Research Society, 26 (5). pp. 693-703. ISSN 1554-527X

Gopalsamy, Ariamala, Shi, Mengxiao, Golas, Jennifer, Vogan, Erik, Jacob, Jaison, Johnson, Mark, Lee, Frederick, Nilakantan, Ramaswamy, Petersen, Roseann, Svenson, Kristin, Chopra, Rajiv, Tam, May S, Wen, Yingxia, Ellingboe, John, Arndt, Kim and Boschelli, Frank (2008) Discovery of benzisoxazoles as potent inhibitors of chaperone heat shock protein 90. Journal of Medicinal Chemistry, 51 (3). pp. 373-375. ISSN 0022-2623

Graf, Christine, Niwa, Satoru, Mueller, Matthias, Kinzel, Bernd and Bornancin, Frederic (2008) Wild-type levels of ceramide and ceramide-1-phosphate in the retina of ceramide kinase-like-deficient mice. Biochemical and Biophysical Research Communications, 373 (1). pp. 159-163. ISSN 1090-2104

Graf, Christine, Zemann, Barbara, Rovina, Philipp, Urtz, Nicole, Schanzer, Andrea, Reuschel, Roland, Mechtcheriakova, Diana, Müller, Matthias, Fischer, Evelin, Reichel, Claudia, Huber, Susanna, Dawson, Janet, Meingassner, Josef, Billich, Andreas, Niwa, Satoru, Badegruber, Rudolf, Van Veldhoven, Paul P, Kinzel, Bernd, Baumruker, Thomas and Bornancin, Frederic (2008) Neutropenia with impaired immune response to Streptococcus pneumoniae in ceramide kinase-deficient mice. Journal of Immunology, 180 (5). pp. 3457-3466. ISSN 0022-1767

Grandl, Joerg, Hu, Hongzhen, Bandell, Michael, Bursulaya, Badry, Schmidt, Manuela, Petrus, Matthew and Patapoutian, Ardem (2008) Pore region of TRPV3 ion channel is specifically required for heat activation. Nature Neuroscience, 11 (9). pp. 1007-1013. ISSN 1546-1726

Grange, Wilfried, Duckely, Myriam, Husale, Sudhir, Jacob, Susan, Engel, Andreas and Hegner, Martin (2008) VirE2: a unique ssDNA-compacting molecular machine. PLoS Biology, 6 (2). e44. ISSN 1545-7885

Grohmann, Rainer and Schindler, Thomas Frederik (2008) Toward robust QSPR models: Synergistic utilization of robust regression and variable elimination. Journal of Computational Chemistry, 29 (6). pp. 847-860. ISSN 1096-987X

Grosshans, Bianka and Novick, Peter (2008) Identification and verification of Sro7p as an effector of the Sec4p Rab GTPase. Methods in Enzymology, 438. pp. 95-108. ISSN 0076-6879

Gryllos, Ioannis, Grifantini, Renata, Colaprico, Annalisa, Cary, Max E, Hakansson, Anders, Carey, David W, Suarez-Chavez, Maria, Kalish, Leslie A, Mitchell, Paul D, White, Gary L and Wessels, Michael R (2008) PerR confers phagocytic killing resistance and allows pharyngeal colonization by group A Streptococcus. PLoS pathogens, 4 (9). e1000145. ISSN 1553-7374

Gschwind, Hans-Peter, Waldmeier, Felix, Zollinger, Markus, Schweitzer, Alain and Grassberger, Maximilian (2008) Pimecrolimus: skin disposition after topical administration in minipigs in vivo and in human skin in vitro. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 33 (1). pp. 9-19. ISSN 0928-0987

Guenova, Emmanuella, Volz, Thomas, Sauer, Karin, Kaesler, Susanne, Müller, Martin R, Wölbing, Florian, Chen, KoMing, Schwaerzler, Christoph, Brossart, Peter, Röcken, Martin and Biedermann, Tilo (2008) IL-4-mediated fine tuning of IL-12p70 production by human DC. European Journal of Immunology, 38 (11). pp. 3138-3149. ISSN 0014-2980

Gulati, Pawan, Gaspers, Lawrence D, Dann, Stephen G, Joaquin, Manel, Nobukuni, Takahiro, Natt, Francois, Kozma, Sara C, Thomas, Andrew P and Thomas, George (2008) Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34. Cell Metabolism, 7 (5). pp. 456-465. ISSN 1932-7420

Hagman, Charlotte, Ricke, Darrell, Ewert, Stefan, Bek, Stephan, Falchetto, Rocco Angelo and Bitsch, Francis (2008) Absolute quantification of monoclonal antibodies in biofluids by liquid chromatography-tandem mass spectrometry. Analytical Chemistry, 80 (4). pp. 1290-1296. ISSN 0003-2700

Halin, Cornelia, Fahrngruber, Hermann, Meingassner, Josef, Bold, Guido, Littlewood-Evans, Amanda, Stuetz, Anton and Detmar, Michael (2008) Inhibition of chronic and acute skin inflammation by treatment with a vascular endothelial growth factor receptor tyrosine kinase inhibitor. The American Journal of Pathology, 173 (1). pp. 265-277. ISSN 1525-2191

Hannon, Jason and Hoyer, Daniel (2008) Molecular biology of 5-HT receptors. Behavioural Brain Research, 195 (1). pp. 198-213. ISSN 1872-7549

Harris, Helen J, Farquhar, Michelle J, Mee, Christopher J, Davis, Christopher, Reynolds, Gary M, Jennings, Adam, Hu, Ke, Yuan, Fei, Deng, HongKui, Hubscher, Stefan G, Han, Jang H, Balfe, Peter and McKeating, Jane A (2008) CD81 and claudin 1 coreceptor association: role in hepatitis C virus entry. Journal of Virology, 82 (10). pp. 5007-5020. ISSN 1098-5514

He, Yan-Ling, Flannery, Brian, Campestrini, Joelle, Leon Reyes, Selene, Zinny, Miguel A, Ligueros-Saylan, Monica and Jarugula, Venkateswar (2008) Effect of food on the pharmacokinetics of a vildagliptin/metformin (50/1000 mg) fixed-dose combination tablet in healthy volunteers. Current Medical Research and Opinion, 24 (6). pp. 1703-1709. ISSN 1473-4877

He, Yan-Ling, Ligueros-Saylan, Monica, Sunkara, Gangadhar, Sabo, Ronald, Zhao, Charlie, Wang, Yibin, Campestrini, Joelle, Pommier, Francoise, Dole, Kiran, Marion, Alan, Dole, William and Howard, Danny (2008) Vildagliptin, a novel dipeptidyl peptidase IV inhibitor, has no pharmacokinetic interactions with the antihypertensive agents amlodipine, valsartan, and ramipril in healthy subjects. Journal of Clinical Pharmacology, 48 (1). pp. 85-95. ISSN 0091-2700

Heikenwalder, Mathias, Prinz, Marco, Zeller, Nicolas, Lang, Karl S, Junt, Tobias, Rossi, Simona, Tumanov, Alexei, Schmidt, Hauke, Priller, Josef, Flatz, Lukas, Rülicke, Thomas, Macpherson, Andrew J, Holländer, Georg A, Nedospasov, Sergei A and Aguzzi, Adriano (2008) Overexpression of lymphotoxin in T cells induces fulminant thymic involution. The American Journal of Pathology, 172 (6). pp. 1555-1570. ISSN 1525-2191

Hertig, Alexandre, Lefevre, Guillaume, Toumi, Karine, Rondeau, Eric, Capeau, Jacqueline, Uzan, Serge and Berkane, Nadia (2008) Soluble endoglin levels during normotensive and hypertensive pregnancies. European journal of obstetrics, gynecology, and reproductive biology, 140 (1). pp. 138-140. ISSN 0301-2115

Hiestand, Peter, Rausch, Martin, Meier, Daniela and Foster, Carolyn-Ann (2008) Ascomycete derivative to MS therapeutic: S1P receptor modulator FTY720. Progress in Drug Research. Fortschritte der Arzneimittelforschung. Progrès des recherches pharmaceutiques, 66. pp. 361-381. ISSN 0071-786X

Hilleringmann, Markus, Giusti, Fabiola, Baudner, Barbara, Masignani, Vega, Covacci, Antonello, Rappuoli, Rino, Barocchi, Michèle A and Ferlenghi, Ilaria (2008) Pneumococcal pili are composed of protofilaments exposing adhesive clusters of Rrg A. PLoS Pathogens, 4 (3). e1000026. ISSN 1553-7374

Hintersteiner, Martin and Auer, Manfred (2008) Single-bead, single-molecule, single-cell fluorescence: technologies for drug screening and target validation. Annals of the New York Academy of Sciences, 1130. pp. 1-11. ISSN 0077-8923

Hirasawa, Ryutaro, Chiba, Hatsune, Kaneda, Masahiro, Tajima, Shoji, Li, En, Jaenisch, Rudolf and Sasaki, Hiroyuki (2008) Maternal and zygotic Dnmt1 are necessary and sufficient for the maintenance of DNA methylation imprints during preimplantation development. Genes & Development, 22 (12). pp. 1607-1616. ISSN 0890-9369

Hoegenauer, Klemens, Billich, Andreas, Pally, Charles, Streiff, Markus, Wagner, Beatrix, Welzenbach, Karl and Nussbaumer, Peter (2008) Phosphorylation by sphingosine kinase 2 is essential for in vivo potency of FTY720 analogues. ChemMedChem, 3 (7). pp. 1027-1029. ISSN 1860-7187

Hogan, Christopher, Simons, Sarah, Zhang, Haiyan and Burdick, Debra (2008) Living with Irresolute Cell Lines in an Automated World. Journal of the Association for Laboratory Automation, 13. pp. 159-167. ISSN 1540-2452

Holden, Neil, Squires, Paul E, Kaur, Manminder, Bland, Rosemary, Jones, Carol and Newton, Robert (2008) Phorbol ester-stimulated NF-kappaB-dependent transcription: roles for isoforms of novel protein kinase C. Cellular Signalling, 20 (7). pp. 1338-1348. ISSN 0898-6568

Holmes, Joseph, Martin, Daniel, Ramsay, C, Ypma, E and Oster, P (2008) Combined administration of serogroup B meningococcal vaccine and conjugated serogroup C meningococcal vaccine is safe and immunogenic in college students. Epidemiology and Infection, 136 (6). pp. 790-799. ISSN 0950-2688

Huang, Bing S, White, Roselyn A, Ahmad, Monir, Jeng, Arco and Leenen, Frans H H (2008) Central infusion of aldosterone synthase inhibitor prevents sympathetic hyperactivity and hypertension by central Na+ in Wistar rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 295 (1). R166-R172. ISSN 0363-6119

Huang, Bing S, White, Roselyn A, Ahmad, Monir, Jeng, Arco and Leenen, Frans H H (2008) Central infusion of aldosterone synthase inhibitor prevents sympathetic hyperactivity and hypertension by central Na+ in Wistar rats. American Journal of Physiology. Regulatory, integrative and comparative physiology, 295 (1). R166-R172. ISSN 0363-6119

Huss, Jon, Orozco, Camilo, Goodale, James, Wu, Chunlei, Batalov, Sergei, Vickers, Tim, Valafar, Faramarz and Su, Andrew (2008) A gene wiki for community annotation of gene function. PLoS Biology, 6 (7). e175. ISSN 1545-7885

Irie, Osamu, Ehara, Takeru, Iwasaki, Atsuko, Yokokawa, Fumiaki, Sakaki, Junichi, Hirao, Hajime, Kanazawa, Takanori, Teno, Naoki, Horiuchi, Miyuki, Umemura, Ichiro, Gunji, Hiroki, Masuya, Keiichi, Hitomi, Yuko, Iwasaki, Genji, Nonomura, Kazuhiko, Tanabe, Keiko, Fukaya, Hiroaki, Kosaka, Takatoshi, Snell, Chris and Hallett, Allan (2008) Discovery of selective and nonpeptidic cathepsin S inhibitors. Bioorganic & Medicinal Chemistry Letters, 18 (14). pp. 3959-3962. ISSN 1464-3405

Issa, Razao, Sorrentino, Rosalinda, Sukkar, Maria B, Sriskandan, Shiranee, Chung, Kian Fan and Mitchell, Jane A (2008) Differential regulation of CCL-11/eotaxin-1 and CXCL-8/IL-8 by gram-positive and gram-negative bacteria in human airway smooth muscle cells. Respiratory Research, 9. p. 30. ISSN 1465-993X

Iwata, Nobuhisa, Tsubuki, Satoshi, Higuchi, Makoto, Staufenbiel, Matthias and Saido, Takaomi C (2008) Pathological significance of AbN3pyroglutamate accumulation in Alzheimer’s disease. Neuroscience Research, 61 (Supplement 1). S122. ISSN 0921-8696

Jacobson, Laura and Cryan, John F. (2008) Evaluation of the anxiolytic-like profile of the GABAB receptor positive modulator CGP7930 in rodents. Neuropharmacology, 54 (5). pp. 854-862. ISSN 0028-3908

Jensen, Michael Rugaard, Ide, Susan, Brueggen, Josef, Schoepfer, Joseph, Motwani, Monica, Wang, X, Radimerski, Thomas, Quadt, Cornelia, Garcia-Echeverria, Carlos and Chene, Patrick (2008) Pharmakokinetic/phamacodynamic relationship in human xenograft models and PBMC’s treated with the Hsp90 inhibitor NVP-AUY922. European Journal of Cancer Supplements, 6 (12). p. 50. ISSN 1359-6349

Jensen, Michael, Schoepfer, Joseph, Radimerski, Thomas, Massey, Andrew, Guy, Chantale, Brueggen, Josef, Quadt, Cornelia, Buckler, Alan, Cozens, Robert, Drysdale, Martin, Garcia-Echeverria, Carlos and Chène, Patrick (2008) NVP-AUY922: a small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models. Breast Cancer Research, 10 (2). R33. ISSN 1465-5411

Jensen, Michael Rugaard, Schoepfer, Joseph, Radimerski, Thomas, Massey, Andrew, Guy, Chantale, Brueggen, Josef, Quadt, Cornelia, Buckler, Alan, Cozens, Robert, Drysdale, Martin J, Garcia-Echeverria, Carlos and Chene, Patrick (2008) NVP-AUY922: a small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models. Breast Cancer Research : BCR, 10 (2). R33. ISSN 1465-542X

Ji, Bin, Maeda, Jun, Sawada, Makoto, Ono, Maiko, Okauchi, Takashi, Inaji, Motoki, Zhang, Ming-Rong, Suzuki, Kazutoshi, Ando, Kiyoshi, Staufenbiel, Matthias, Trojanowski, John Q, Lee, Virginia M Y, Higuchi, Makoto and Suhara, Tetsuya (2008) Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologies. The Journal of Neuroscience: the official journal of the Society for Neuroscience, 28 (47). pp. 12255-12267. ISSN 1529-2401

Johansson, Gunnar, Mahller, Yonatan Y, Collins, Margaret H, Kim, Mi-Ok, Nobukuni, Takahiro, Perentesis, John, Cripe, Timothy P, Lane, Heidi, Kozma, Sara C, Thomas, George and Ratner, Nancy (2008) Effective in vivo targeting of the mammalian target of rapamycin pathway in malignant peripheral nerve sheath tumors. Molecular Cancer Therapeutics, 7 (5). pp. 1237-1245. ISSN 1535-7163

Jones, Brendan, Su, Hui, Bhat, Audesh, Lei, Hong, Bajko, Jeffrey, Hevi, Sarah, Baltus, Gretchen, Kadam, Shilpa, Zhai, Huili, Valdez, Reginald, Gonzalo, Susana, Zhang, Yi, Li, En and Chen, Taiping (2008) The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure. PLoS Genetics, 4 (9). e1000190. ISSN 1553-7404

Juckem, Laura K, Boehme, Karl W, Feire, Adam and Compton, Teresa (2008) Differential initiation of innate immune responses induced by human cytomegalovirus entry into fibroblast cells. Journal of Immunology (Baltimore, Md. : 1950), 180 (7). pp. 4965-4977. ISSN 0022-1767

Kaiser, Martin, Mieth, Maren, Liebisch, Peter, Oberlaender, Romy, Rademacher, Jessica, Jakob, Christian, Kleeberg, Lorenz, Fleissner, Claudia, Braendle, Edgar, Peters, Malte, Stover, David, Sezer, Orhan and Heider, Ulrike (2008) Serum concentrations of DKK-1 correlate with the extent of bone disease in patients with multiple myeloma. European Journal of Haematology, 80 (6). pp. 490-494. ISSN 1600-0609

Karmouty Quintana, Harry, Ble, Francois-Xavier, Cannet, Catherine, Zurbruegg, Stefan, Fozard, John R., Page, Christopher and Beckmann, Nicolau (2008) In vivo pharmacological evaluation of compound 48/80-induced airways oedema by MRI. British Journal of Pharmacology, 154 (5). pp. 1063-1072. ISSN 0007-1188

Kawahara, E, Miyake, T, Matsuura, N, Umemura, I, Masuya, Keiichi, Kanazawa, T, Meyer, T, Mestan, Juergen, Hatakeyama, Shinji and Ohmori, Osamu (2008) Discovery of potent and selective focal adhesion kinase inhibitors. European Journal of Cancer Supplements, 6 (12). p. 43. ISSN 1359-6349

Klionsky, Daniel J, Abeliovich, Hagai, Agostinis, Patrizia, Agrawal, Devendra K, Aliev, Gjumrakch, Askew, David S, Baba, Misuzu, Baehrecke, Eric H, Bahr, Ben A, Ballabio, Andrea, Bamber, Bruce A, Bassham, Diane C, Bergamini, Ettore, Bi, Xiaoning, Biard-Piechaczyk, Martine, Blum, Janice S, Bredesen, Dale E, Brodsky, Jeffrey L, Brumell, John H, Brunk, Ulf T, Bursch, Wilfried, Camougrand, Nadine, Cebollero, Eduardo, Cecconi, Francesco, Chen, Yingyu, Chin, Lih-Shen, Choi, Augustine, Chu, Charleen T, Chung, Jongkyeong, Clarke, Peter G H, Clark, Robert S B, Clarke, Steven G, Clave, Corinne, Cleveland, John L, Codogno, Patrice, Colombo, Maria I, Coto-Montes, Ana, Cregg, James M, Cuervo, Ana Maria, Debnath, Jayanta, Demarchi, Francesca, Dennis, Patrick B, Dennis, Phillip A, Deretic, Vojo, Devenish, Rodney J, Di Sano, Federica, Dice, J Fred, Difiglia, Marian, Dinesh-Kumar, Savithramma, Distelhorst, Clark W, Djavaheri-Mergny, Mojgan, Dorsey, Frank C, Droge, Wulf, Dron, Michel, Dunn, William A, Duszenko, Michael, Eissa, N Tony, Elazar, Zvulun, Esclatine, Audrey, Eskelinen, Eeva-Liisa, Fesus, Laszlo, Finley, Kim D, Fuentes, Jose M, Fueyo, Juan, Fujisaki, Kozo, Galliot, Brigitte, Gao, Fen-Biao, Gewirtz, David A, Gibson, Spencer B, Gohla, Antje, Goldberg, Alfred L, Gonzalez, Ramon, González-Estévez, Cristina, Gorski, Sharon, Gottlieb, Roberta A, Haussinger, Dieter, He, You-Wen, Heidenreich, Kim, Hill, Joseph A, Hoyer-Hansen, Maria, Hu, Xun, Huang, Wei-Pang, Iwasaki, Akiko, Jaattela, Marja, Jackson, William T, Jiang, Xuejun, Jin, Shengkan, Johansen, Terje, Jung, Jae U, Kadowaki, Motoni, Kang, Chanhee, Kelekar, Ameeta, Kessel, David H, Kiel, Jan A K W, Kim, Hong Pyo, Kimchi, Adi, Kinsella, Timothy J, Kiselyov, Kirill, Kitamoto, Katsuhiko, Knecht, Erwin, Komatsu, Masaaki, Kominami, Eiki, Kondo, Seiji, Kovács, Attila L, Kroemer, Guido, Kuan, Chia-Yi, Kumar, Rakesh, Kundu, Mondira, Landry, Jacques, Laporte, Marianne, Le, Weidong, Lei, Huan-Yao, Lenardo, Michael J, Levine, Beth, Lieberman, Andrew, Lim, Kah-Leong, Lin, Fu-Cheng, Liou, Willisa, Liu, Leroy F, Lopez-Berestein, Gabriel, Lopez-Otin, Carlos, Lu, Bo, Macleod, Kay F, Malorni, Walter, Martinet, Wim, Matsuoka, Ken, Mautner, Josef, Meijer, Alfred J, Melendez, Alicia, Michels, Paul, Miotto, Giovanni, Mistiaen, Wilhelm P, Mizushima, Noboru, Mograbi, Baharia, Monastyrska, Iryna, Moore, Michael N, Moreira, Paula I, Moriyasu, Yuji, Motyl, Tomasz, Munz, Christian, Murphy, Leon, Naqvi, Naweed I, Neufeld, Thomas P, Nishino, Ichizo, Nixon, Ralph A, Noda, Takeshi, Nurnberg, Bernd, Ogawa, Michinaga, Oleinick, Nancy L, Olsen, Laura J, Ozpolat, Bulent, Paglin, Shoshana, Palmer, Glen E, Papassideri, Issidora, Parkes, Miles, Perlmutter, David H, Perry, George, Piacentini, Mauro, Pinkas-Kramarski, Ronit, Prescott, Mark, Proikas-Cezanne, Tassula, Raben, Nina, Rami, Abdelhaq, Reggiori, Fulvio, Rohrer, Bärbel, Rubinsztein, David C, Ryan, Kevin M, Sadoshima, Junichi, Sakagami, Hiroshi, Sakai, Yasuyoshi, Sandri, Marco, Sasakawa, Chihiro, Sass, Miklós, Schneider, Claudio, Seglen, Per O, Seleverstov, Oleksandr, Settleman, Jeffrey, Shacka, John J, Shapiro, Irving M, Sibirny, Andrei, Silva-Zacarin, Elaine C M, Simon, Hans-Uwe, Simone, Cristiano, Simonsen, Anne, Smith, Mark A, Spanel-Borowski, Katharina, Srinivas, Vickram, Steeves, Meredith, Stenmark, Harald, Stromhaug, Per E, Subauste, Carlos S, Sugimoto, Seiichiro, Sulzer, David, Suzuki, Toshihiko, Swanson, Michele S, Tabas, Ira, Takeshita, Fumihiko, Talbot, Nicholas J, Talloczy, Zsolt, Tanaka, Keiji, Tanaka, Kozo, Tanida, Isei, Taylor, Graham S, Taylor, J Paul, Terman, Alexei, Tettamanti, Gianluca, Thompson, Craig B, Thumm, Michael, Tolkovsky, Aviva M, Tooze, Sharon A, Truant, Ray, Tumanovska, Lesya V, Uchiyama, Yasuo, Ueno, Takashi, Uzcátegui, Néstor L, van der Klei, Ida, Vaquero, Eva C, Vellai, Tibor, Vogel, Michael W, Wang, Hong-Gang, Webster, Paul, Wiley, John W, Xi, Zhijun, Xiao, Gutian, Yahalom, Joachim, Yang, Jin-Ming, Yap, George, Yin, Xiao-Ming, Yoshimori, Tamotsu, Yu, Li, Yue, Zhenyu, Yuzaki, Michisuke, Zabirnyk, Olga, Zheng, Xiaoxiang, Zhu, Xiongwei and Deter, Russell L (2008) Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy, 4 (2). pp. 151-175. ISSN 1554-8635

Klionsky, Daniel J, Abeliovich, Hagai, Agostinis, Patrizia, Agrawal, Devendra K, Aliev, Gjumrakch, Askew, David S, Baba, Misuzu, Baehrecke, Eric H, Bahr, Ben A, Ballabio, Andrea, Bamber, Bruce A, Bassham, Diane C, Bergamini, Ettore, Bi, Xiaoning, Biard-Piechaczyk, Martine, Blum, Janice S, Bredesen, Dale E, Brodsky, Jeffrey L, Brumell, John H, Brunk, Ulf T, Bursch, Wilfried, Camougrand, Nadine, Cebollero, Eduardo, Cecconi, Francesco, Chen, Yingyu, Chin, Lih-Shen, Choi, Augustine, Chu, Charleen T, Chung, Jongkyeong, Clarke, Peter G H, Clark, Robert S B, Clarke, Steven G, Clavé, Corinne, Cleveland, John L, Codogno, Patrice, Colombo, María I, Coto-Montes, Ana, Cregg, James M, Cuervo, Ana Maria, Debnath, Jayanta, Demarchi, Francesca, Dennis, Patrick B, Dennis, Phillip A, Deretic, Vojo, Devenish, Rodney J, Di Sano, Federica, Dice, J Fred, Difiglia, Marian, Dinesh-Kumar, Savithramma, Distelhorst, Clark W, Djavaheri-Mergny, Mojgan, Dorsey, Frank C, Dröge, Wulf, Dron, Michel, Dunn, William A, Duszenko, Michael, Eissa, N Tony, Elazar, Zvulun, Esclatine, Audrey, Eskelinen, Eeva-Liisa, Fésüs, László, Finley, Kim D, Fuentes, José M, Fueyo, Juan, Fujisaki, Kozo, Galliot, Brigitte, Gao, Fen-Biao, Gewirtz, David A, Gibson, Spencer B, Gohla, Antje, Goldberg, Alfred L, Gonzalez, Ramon, González-Estévez, Cristina, Gorski, Sharon, Gottlieb, Roberta A, Häussinger, Dieter, He, You-Wen, Heidenreich, Kim, Hill, Joseph A, Høyer-Hansen, Maria, Hu, Xun, Huang, Wei-Pang, Iwasaki, Akiko, Jäättelä, Marja, Jackson, William T, Jiang, Xuejun, Jin, Shengkan, Johansen, Terje, Jung, Jae U, Kadowaki, Motoni, Kang, Chanhee, Kelekar, Ameeta, Kessel, David H, Kiel, Jan A K W, Kim, Hong Pyo, Kimchi, Adi, Kinsella, Timothy J, Kiselyov, Kirill, Kitamoto, Katsuhiko, Knecht, Erwin, Komatsu, Masaaki, Kominami, Eiki, Kondo, Seiji, Kovács, Attila L, Kroemer, Guido, Kuan, Chia-Yi, Kumar, Rakesh, Kundu, Mondira, Landry, Jacques, Laporte, Marianne, Le, Weidong, Lei, Huan-Yao, Lenardo, Michael J, Levine, Beth, Lieberman, Andrew, Lim, Kah-Leong, Lin, Fu-Cheng, Liou, Willisa, Liu, Leroy F, Lopez-Berestein, Gabriel, López-Otín, Carlos, Lu, Bo, Macleod, Kay F, Malorni, Walter, Martinet, Wim, Matsuoka, Ken, Mautner, Josef, Meijer, Alfred J, Meléndez, Alicia, Michels, Paul, Miotto, Giovanni, Mistiaen, Wilhelm P, Mizushima, Noboru, Mograbi, Baharia, Monastyrska, Iryna, Moore, Michael N, Moreira, Paula I, Moriyasu, Yuji, Motyl, Tomasz, Münz, Christian, Murphy, Leon, Naqvi, Naweed I, Neufeld, Thomas P, Nishino, Ichizo, Nixon, Ralph A, Noda, Takeshi, Nürnberg, Bernd, Ogawa, Michinaga, Oleinick, Nancy L, Olsen, Laura J, Ozpolat, Bulent, Paglin, Shoshana, Palmer, Glen E, Papassideri, Issidora, Parkes, Miles, Perlmutter, David H, Perry, George, Piacentini, Mauro, Pinkas-Kramarski, Ronit, Prescott, Mark, Proikas-Cezanne, Tassula, Raben, Nina, Rami, Abdelhaq, Reggiori, Fulvio, Rohrer, Bärbel, Rubinsztein, David C, Ryan, Kevin M, Sadoshima, Junichi, Sakagami, Hiroshi, Sakai, Yasuyoshi, Sandri, Marco, Sasakawa, Chihiro, Sass, Miklós, Schneider, Claudio, Seglen, Per O, Seleverstov, Oleksandr, Settleman, Jeffrey, Shacka, John J, Shapiro, Irving M, Sibirny, Andrei, Silva-Zacarin, Elaine C M, Simon, Hans-Uwe, Simone, Cristiano, Simonsen, Anne, Smith, Mark A, Spanel-Borowski, Katharina, Srinivas, Vickram, Steeves, Meredith, Stenmark, Harald, Stromhaug, Per E, Subauste, Carlos S, Sugimoto, Seiichiro, Sulzer, David, Suzuki, Toshihiko, Swanson, Michele S, Tabas, Ira, Takeshita, Fumihiko, Talbot, Nicholas J, Tallóczy, Zsolt, Tanaka, Keiji, Tanaka, Kozo, Tanida, Isei, Taylor, Graham S, Taylor, J Paul, Terman, Alexei, Tettamanti, Gianluca, Thompson, Craig B, Thumm, Michael, Tolkovsky, Aviva M, Tooze, Sharon A, Truant, Ray, Tumanovska, Lesya V, Uchiyama, Yasuo, Ueno, Takashi, Uzcátegui, Néstor L, van der Klei, Ida, Vaquero, Eva C, Vellai, Tibor, Vogel, Michael W, Wang, Hong-Gang, Webster, Paul, Wiley, John W, Xi, Zhijun, Xiao, Gutian, Yahalom, Joachim, Yang, Jin-Ming, Yap, George, Yin, Xiao-Ming, Yoshimori, Tamotsu, Yu, Li, Yue, Zhenyu, Yuzaki, Michisuke, Zabirnyk, Olga, Zheng, Xiaoxiang, Zhu, Xiongwei and Deter, Russell L (2008) Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy, 4 (2). pp. 151-175. ISSN 1554-8635

Koeberling, Oliver, Seubert, Anja and Granoff, Dan M (2008) Bactericidal antibody responses elicited by a meningococcal outer membrane vesicle vaccine with overexpressed factor H-binding protein and genetically attenuated endotoxin. The Journal of Infectious Diseases, 198 (2). pp. 262-270. ISSN 0022-1899

Koehn, Jadranka, Fountoulakis, M and Krapfenbauer, Kurt (2008) Multiple drug resistance associated with function of ABC-transporters in diabetes mellitus: molecular mechanism and clinical relevance. Infectious Disorders Drug Targets, 8 (2). pp. 109-118. ISSN 1871-5265

Koenders, Marije I, Devesa, Isabel, Marijnissen, Renoud J, Abdollahi-Roodsaz, Shahla, Boots, Annemieke M H, Walgreen, Birgitte, Di Padova, Franco E., Nicklin, Martin J H, Joosten, Leo A B and van den Berg, Wim B (2008) Interleukin-1 drives pathogenic Th17 cells during spontaneous arthritis in interleukin-1 receptor antagonist-deficient mice. Arthritis and Rheumatism, 58 (11). pp. 3461-3470. ISSN 0004-3591

Komatsu, Noriko, Waki, Michihiko, Sue, Mayumi, Tokuda, Chikashi, Kasaoka, Tatsuhiko, Nakajima, Motowo, Higashi, Nobuaki and Irimura, Tatsuro (2008) Heparanase expression in B16 melanoma cells and peripheral blood neutrophils before and after extravasation detected by novel anti-mouse heparanase monoclonal antibodies. Journal of Immunological Methods, 331 (1-2). pp. 82-93. ISSN 0022-1759

Konig, H, Holtz, M, Modi, H, Manley, Paul W., Holyoake, T L, Forman, S J and Bhatia, R (2008) Enhanced BCR-ABL kinase inhibition does not result in increased inhibition of downstream signaling pathways or increased growth suppression in CML progenitors. Leukemia: official journal of the Leukemia Society of America, Leukemia Research Fund, U.K, 22 (4). pp. 748-755. ISSN 1476-5551

Kovarik, John M., Riviere, Gilles-Jacques, Neddermann, Daniel, Maton, Steve, Hunt, Thomas L and Schmouder, Robert (2008) A mechanistic study to assess whether isoproterenol can reverse the negative chronotropic effect of fingolimod. Journal of Clinical Pharmacology, 48 (3). pp. 303-310. ISSN 0091-2700

Kovarik, John M., Riviere, Gilles-Jacques, Neddermann, Daniel, Maton, Steve, Hunt, Tom and Schmouder, Robert (2008) A mechanistic study to assess whether isoproterenol can reverse the negative chronotropic effect of fingolimod. Journal of Clinical Pharmacology, 48 (3). pp. 303-310. ISSN 0091-2700

Kovarik, John M., Slade, Alan, Riviere, Gilles-Jacques, Neddermann, Daniel, Maton, Steve, Hunt, Tom and Schmouder, Robert (2008) The ability of atropine to prevent and reverse the negative chronotropic effect of fingolimod in healthy subjects. British Journal of Clinical Pharmacology, 66 (2). pp. 199-206. ISSN 1365-2125

Kulasingam, Vathany, Smith, Christopher, Batruch, Ihor, Buckler, Alan, Jeffery, Douglas and Diamandis, Eleftherios P (2008) "Product ion monitoring" assay for prostate-specific antigen in serum using a linear ion-trap. Journal of Proteome Research, 7 (2). pp. 640-647. ISSN 1535-3893

Kulasingam, Vathany, Smith, Christopher R, Batruch, Ihor, Buckler, Alan, Jeffery, Douglas and Diamandis, Eleftherios P (2008) "Product ion monitoring" assay for prostate-specific antigen in serum using a linear ion-trap. Journal of Proteome Research, 7 (2). pp. 640-647. ISSN 1535-3893

Kurabachew, Mekonnen, Lu, Stephen, Krastel, Philipp, Schmitt, Esther, Suresh, Bangalolore, Goh, Anne, Knox, John, Ma, Ngai Ling, Jiricek, Jan, Beer, David, Cynamon, Michael, Petersen, Frank, Dartois, Veronique, Keller, Thomas, Dick, Thomas and Sambandamurthy, Vasan (2008) Lipiarmycin targets RNA polymerase and has good activity against multidrug-resistant strains of Mycobacterium tuberculosis. The Journal of Antimicrobial Chemotherapy, 62 (4). pp. 713-719. ISSN 1460-2091

Kuramochi-Miyagawa, Satomi, Watanabe, Toshiaki, Gotoh, Kengo, Totoki, Yasushi, Toyoda, Atsushi, Ikawa, Masahito, Asada, Noriko, Kojima, Kanako, Yamaguchi, Yuka, Ijiri, Takashi W, Hata, Kenichiro, Li, En, Matsuda, Yoichi, Kimura, Tohru, Okabe, Masaru, Sakaki, Yoshiyuki, Sasaki, Hiroyuki and Nakano, Toru (2008) DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes. Genes & Development, 22 (7). pp. 908-917. ISSN 0890-9369

Kurash, Yuliya, Lei, Hong, Shen, Qiong, Marston, Wendy, Granda, Brian, Fan, Hong, Wall, Daniel, Li, En and Gaudet, Francois (2008) Methylation of p53 by Set7/9 mediates p53 acetylation and activity in vivo. Molecular Cell, 29 (3). pp. 392-400. ISSN 1097-2765

Lan, Yuk Yuen, Tokita, Daisuke, Wang, Zhiliang, Wang, Hao Chen, Zhan, Jianghua, Brinkmann, Volker and Thomson, Angus W (2008) Sphingosine 1-phosphate receptor agonism impairs skin dendritic cell migration and homing to secondary lymphoid tissue: association with prolonged allograft survival. Transplant Immunology, 20 (1-2). pp. 88-94. ISSN 0966-3274

Lang, Sven Arke, Brecht, Isabel, Moser, Christian, Obed, Aiman, Batt, David, Schlitt, Hans Juergen, Geissler, Edward Kenneth and Stoeltzing, Oliver (2008) Dual inhibition of Raf and VEGFR2 reduces growth and vascularization of hepatocellular carcinoma in an experimental model. Langenbeck's Archives of Surgery / Deutsche Gesellschaft für Chirurgie, 393 (3). pp. 333-341. ISSN 1435-2451

Lazaro, Elisabet, Lowe, Philip, Briand, Xavier and Faller, Bernard (2008) New approach to measure protein binding based on a parallel artificial membrane assay and human serum albumin. Journal of Medicinal Chemistry, 51 (7). pp. 2009-2017. ISSN 0022-2623

Le Coutre, Philipp, Ottmann, Oliver G, Giles, Francis, Kim, Dong-Wook, Cortes, Jorge, Gattermann, Norbert, Apperley, Jane F, Larson, Richard A, Abruzzese, Elisabetta, O'Brien, Stephen G, Kuliczkowski, Kazimierz, Hochhaus, Andreas, Mahon, Francois-Xavier, Saglio, Giuseppe, Gobbi, Marco, Kwong, Yok-Lam, Baccarani, Michele, Hughes, Timothy, Martinelli, Giovanni, Radich, Jerald P, Zheng, Ming, Shou, Yaping and Kantarjian, Hagop (2008) Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is active in patients with imatinib-resistant or -intolerant accelerated-phase chronic myelogenous leukemia. Blood, 111 (4). pp. 1834-1839. ISSN 0006-4971

Lee, Seung-Hyo, Prince, Joseph E, Rais, Muhammad, Kheradmand, Farrah, Ballantyne, Christie M, Weitz Schmidt, Gabriele, Smith, C Wayne and Corry, David B (2008) Developmental control of integrin expression regulates Th2 effector homing. Journal of Immunology (Baltimore, Md. : 1950), 180 (7). pp. 4656-4667. ISSN 0022-1767

Lefevre, Gilbert, Pommier, Françoise, Sedek, Greg, Allison, Mark, Huang, Hsun-Lun Aaron, Kiese, Beate, Ho, Yu-Yun and Appel Dingemanse, Silke (2008) Pharmacokinetics and bioavailability of the novel rivastigmine transdermal patch versus rivastigmine oral solution in healthy elderly subjects. Journal of clinical pharmacology, 48 (2). pp. 246-252. ISSN 0091-2700

Lefevre, Gilbert, Sedek, Greg, Jhee, S S, Leibowitz, M T, Huang, H-La, Enz, Albert, Maton, Steve, Ereshefsky, L, Pommier, Francoise, Schmidli, Heinz and Appel Dingemanse, Silke (2008) Pharmacokinetics and pharmacodynamics of the novel daily rivastigmine transdermal patch compared with twice-daily capsules in Alzheimer's disease patients. Clinical pharmacology and therapeutics, 83 (1). pp. 106-114. ISSN 1532-6535

Li, Jing, Knee, Deborah, Wang, Youzhen, Zhang, Qingxiu, Johnson, Jennifer, Cheng, Jane, He, Helen, Miller, Christine, Li, Zhifang, Kowal, Colleen, Eckman Iii, Joseph, Tang, Betty, Yuan, Jing, Chen, Liqing, Deveraux, Quinn, Nasoff, Marc and Stover, David (2008) LBY135, a Novel Anti-DR5 Agonistic Antibody Induces Tumor Cell–Specific Cytotoxic Activity in Human Colon Tumor Cell Lines and Xenografts. Drug Development Research, 69 (2). pp. 69-82. ISSN 0272-4391

Li, Cheng, Beroukhim, Rameen, Weir, Barbara, Winckler, Wendy, Garraway, Levi, Sellers, William and Meyerson, Matthew (2008) Major copy proportion analysis of tumor samples using SNP arrays. BMC Bioinformatics, 9 (1). p. 204. ISSN 1471-2105

Li, Li-Fu, Liao, Shuen-Kuei, Huang, Chung-Chi, Hung, Ming-Jui and Quinn, Deborah (2008) Serine/threonine kinase-protein kinase B and extracellular signal-regulated kinase regulate ventilator-induced pulmonary fibrosis after bleomycin-induced acute lung injury: a prospective, controlled animal experiment. Critical care (London, England), 12 (4). R103. ISSN 1466-609X

Lietha, Daniel and Eck, Michael J (2008) Crystal structures of the FAK kinase in complex with TAE226 and related bis-anilino pyrimidine inhibitors reveal a helical DFG conformation. PloS one, 3 (11). e3800. ISSN 1932-6203

Lim, Siew Pheng, Wen, Daying, Yap, Thai Leong, Yan, Chung Ka, Lescar, Julien and Vasudevan, Subhash (2008) A scintillation proximity assay for dengue virus NS5 2'-O-methyltransferase-kinetic and inhibition analyses. Antiviral research, 80 (3). pp. 360-369. ISSN 1872-9096

Lisztwan, Joanna, Pornon, Astrid, Chen, Bin, Chen, Shiuan and Evans, Dean Brent (2008) The aromatase inhibitor letrozole and inhibitors of insulin-like growth factor I receptor synergistically induce apoptosis in in vitro models of estrogen-dependent breast cancer. Breast Cancer Research, 10 (4). R56. ISSN 1465-5411

Liu, Bo, Chang, Jonathan, Gordon, William, Isbell, John, Zhou, Yingyao and Tuntland, Tove (2008) Snapshot PK: a rapid rodent in vivo preclinical screening approach. Drug Discovery Today, 13 (7-8). pp. 360-367. ISSN 1359-6446

Liu, Xin, Wang, Ling, Zhao, Kehao, Thompson, Paul R, Hwang, Yousang, Marmorstein, Ronen and Cole, Philip A (2008) The structural basis of protein acetylation by the p300/CBP transcriptional coactivator. Nature, 451 (7180). pp. 846-850. ISSN 1476-4687

Liu, Andrew, Tran, Hien, Zhang, Eric, Priest, Aaron A, Welsh, David K and Kay, Steve A (2008) Redundant function of REV-ERBalpha and beta and non-essential role for Bmal1 cycling in transcriptional regulation of intracellular circadian rhythms. PLoS Genetics, 4 (2). e1000023. ISSN 1553-7404

Lu, Qiang and An, W Frank (2008) Impact of novel screening technologies on ion channel drug discovery. Combinatorial Chemistry & High Throughput Screening, 11 (3). pp. 185-194. ISSN 1386-2073

Lu, Xiangdong, Kovalev, Grigoriy I, Chang, Hua, Kallin, Eric, Knudsen, Geoffrey, Xia, Li, Mishra, Nilamadhab, Ruiz, Phillip, Li, En, Su, Lishan and Zhang, Yi (2008) Inactivation of NuRD component Mta2 causes abnormal T cell activation and lupus-like autoimmune disease in mice. The Journal of Biological Chemistry, 283 (20). pp. 13825-13833. ISSN 0021-9258

Lu, Hong, Rateri, Debra L, Feldman, David, Jr, Richard J Charnigo, Fukamizu, Akiyoshi, Ishida, Junji, Oesterling, Elizabeth G, Cassis, Lisa A and Daugherty, Alan (2008) Renin inhibition reduces hypercholesterolemia-induced atherosclerosis in mice. The Journal of Clinical Investigation, 118 (3). pp. 984-993. ISSN 0021-9738

Luo, Dahai, Xu, Ting, Watson, Randall, Scherer-Becker, Daniela, Sampath, Aruna, Jahnke, Wolfgang, Yeong, Sui Sum, Wang, Chern Hoe, Lim, Siew Pheng, Strongin, Alex, Vasudevan, Subhash and Lescar, Julien (2008) Insights into RNA unwinding and ATP hydrolysis by the flavivirus NS3 protein. The EMBO Journal, 27 (23). pp. 3209-3219. ISSN 1460-2075

Luqman, Mohammad, Klabunde, Sha, Lin, Karen, Georgakis, Georgios V., Cherukuri, Anu, Holash, Jocelyn, Goldbeck, Cheryl, Xu, Xiaomei, Kadel, Edward E., Lee, Sang Hoon, Aukerman, Sharon, Jallal, Bahija, Aziz, Natasha, Weng, Wen-Kai, Wierda, William, O'Brien, Susan and Younes, Anas (2008) The antileukemia activity of a human anti-CD40 antagonist antibody, HCD122, on human chronic lymphocytic leukemia cells. Blood, 112 (3). pp. 711-720. ISSN 1528-0020

Lysaght, Michael J, Jaklenec, Ana and Deweerd, Elizabeth (2008) Great expectations: private sector activity in tissue engineering, regenerative medicine, and stem cell therapeutics. Tissue engineering. Part A, 14 (2). pp. 305-315. ISSN 1937-3341

Lyukmanova, Ekaterina N, Shenkarev, Zakhar O, Paramonov, Alexander S, Sobol, Alexander G, Ovchinnikova, Tatiana V, Chupin, Vladimir V, Kirpichnikov, Mikhail P, Blommers, Marcel J.J. and Arseniev, Alexander S (2008) Lipid-protein nanoscale bilayers: a versatile medium for NMR investigations of membrane proteins and membrane-active peptides. Journal of the American Chemical Society, 130 (7). pp. 2140-2141. ISSN 1520-5126

Ma, Qicheng, Chirn, Gung-Wei, Szustakowski, Joseph, Bakhtiarova, Adel, Kosinski, Penelope, Kemp, Daniel and Nirmala, Nanguneri (2008) Uncovering mechanisms of transcriptional regulations by systematic mining of cis regulatory elements with gene expression profiles. BioData Mining, 1 (1). p. 4. ISSN 1756-0381

Mac Sweeney, Aengus, Gil Parrado, Shirley, Vinzenz, Daniela, Bernardi, Anna, Hein, Andreas, Bodendorf, Ursula, Erbel, Paulus, Logel, Claude and Gerhartz, Bernd (2008) Structural basis for the substrate specificity of bone morphogenetic protein 1/tolloid-like metalloproteases. Journal of Molecular Biology, 384 (1). pp. 228-239. ISSN 1089-8638

Maira, Sauveur-Michel, Stauffer, Frederic, Brueggen, Josef, Furet, Pascal, Schnell, Christian, Fritsch, Christine, Brachmann, Saskia, Chene, Patrick, De Pover, Alain, Schoemaker, Kevin, Fabbro, Doriano, Gabriel, Daniela, Simonen, Marjo, Murphy, Leon, Finan, Peter, Sellers, William and Garcia-Echeverria, Carlos (2008) Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity. Molecular Cancer Therapeutics, 7 (7). pp. 1851-1863. ISSN 1535-7163

Maira, Sauveur-Michel, Voliva, Charles and Garcia-Echeverria, Carlos (2008) Class IA phosphatidylinositol 3-kinase: from their biologic implication in human cancers to drug discovery. Expert Opinion on Therapeutic Targets, 12 (2). pp. 223-238. ISSN 1744-7631

Maiso, Patricia, Ocio, Enrique M, Garayoa, Mercedes, Montero, Juan C, Hofmann, Francesco, Garcia-Echeverria, Carlos, Zimmermann, Johann, Pandiella, Atanasio and San Miguel, Jesus F (2008) The insulin-like growth factor-I receptor inhibitor NVP-AEW541 provokes cell cycle arrest and apoptosis in multiple myeloma cells. British Journal of Haematology, 141 (4). pp. 470-482. ISSN 1365-2141

Majumdar, Alokes, Muniandy, Parameswary A, Liu, Jia, Liu, Ji-lan, Liu, Su-ting, Cuenoud, Bernard and Seidman, Michael M (2008) Targeted gene knock in and sequence modulation mediated by a psoralen-linked triplex-forming oligonucleotide. The Journal of Biological Chemistry, 283 (17). pp. 11244-11252. ISSN 0021-9258

Majumder, Pradip K, Grisanzio, Chiara, O'Connell, Fionnuala, Barry, Marc, Brito, Joseph M, Xu, Qing, Guney, Isil, Berger, Raanan, Herman, Paula, Bikoff, Rachel, Fedele, Giuseppe, Baek, Won-Ki, Wang, Shunyou, Ellwood-Yen, Katharine, Wu, Hong, Sawyers, Charles L, Signoretti, Sabina, Hahn, William C, Loda, Massimo and Sellers, William (2008) A prostatic intraepithelial neoplasia-dependent p27 Kip1 checkpoint induces senescence and inhibits cell proliferation and cancer progression. Cancer Cell, 14 (2). pp. 146-155. ISSN 1878-3686

Malyala, Padma, Chesko, James, Ugozzoli, Mildred, Goodsell, Amanda, Zhou, Fengmin, Vajdy, Michael, O'Hagan, Derek T and Singh, Manmohan (2008) The potency of the adjuvant, CpG oligos, is enhanced by encapsulation in PLG microparticles. Journal of Pharmaceutical Sciences, 97 (3). pp. 1155-1164. ISSN 0022-3549

Marrer, Estelle and Dieterle, Frank (2008) Biomarkers in oncology drug development: rescuers or troublemakers? Expert Opinion on Drug Metabolism & Toxicology, 4 (11). pp. 1391-1402. ISSN 1742-5255

Martin, Eric and Sullivan, David (2008) AutoShim: empirically corrected scoring functions for quantitative docking with a crystal structure and IC50 training data. Journal of Chemical Information and Modeling, 48 (4). pp. 861-872. ISSN 1549-9596

Martin, Eric and Sullivan, David (2008) Surrogate AutoShim: predocking into a universal ensemble kinase receptor for three dimensional activity prediction, very quickly, without a crystal structure. Journal of Chemical Information and Modeling, 48 (4). pp. 873-881. ISSN 1549-9596

Martin, Eric, Mukherjee, Prasenjit and Sirockin, Finton (2008) Profile-QSAR and Surrogate AutoShim Protein-Family Modeling of Proteases. J Chem Inf Model. 2008 Apr;48(4):873-81. doi: 10.1021/ci700455u..

Martins, A. S., Ordonez, J. L., Garcia-Sanchez, A., Herrero, D., Sevillano, V., Osuna, D., Mackintosh, C., Caballero, G., Otero, A. P., Poremba, C., Madoz-Gurpide, J. and de Alava, E. (2008) A Pivotal Role for Heat Shock Protein 90 in Ewing Sarcoma Resistance to Anti-Insulin-like Growth Factor 1 Receptor Treatment: In vitro and In vivo Study. Cancer Research, 68 (15). pp. 6260-6270. ISSN 0008-5472

Matter, Alex and Keller, Thomas (2008) Impact of non-profit organizations on drug discovery: opportunities, gaps, solutions. Drug Discovery Today, 13 (7-8). pp. 347-352. ISSN 1359-6446

Mayr, Lorenz and Fuerst, Peter (2008) The future of high-throughput screening. Journal of Biomolecular Screening : the official journal of the Society for Biomolecular Screening, 13 (6). pp. 443-448. ISSN 1087-0571

McLaughlin, Bridget E, Baumgarth, Nicole, Bigos, Martin, Roederer, Mario, De Rosa, Stephen C, Altman, John D, Nixon, Douglas F, Ottinger, Janet, Li, Judy, Beckett, Laurel, Shacklett, Barbara L, Evans, Thomasg and Asmuth, David M (2008) Nine-color flow cytometry for accurate measurement of T cell subsets and cytokine responses. Part II: Panel performance across different instrument platforms. Cytometry. Part A : the journal of the International Society for Analytical Cytology, 73 (5). pp. 411-420. ISSN 1552-4930

McLaughlin, Bridget E, Baumgarth, Nicole, Bigos, Martin, Roederer, Mario, De Rosa, Stephen C, Altman, John D, Nixon, Douglas F, Ottinger, Janet, Oxford, Carol, Evans, Thomasg and Asmuth, David M (2008) Nine-color flow cytometry for accurate measurement of T cell subsets and cytokine responses. Part I: Panel design by an empiric approach. Cytometry. Part A : the journal of the International Society for Analytical Cytology, 73 (5). pp. 400-410. ISSN 1552-4930

Mcdonald, Lisa, Sheppard, W F, Staveley, S M, Sohal, Bindi, Tattersall, F D and Hutson, P H (2008) Discriminative stimulus effects of tiagabine and related GABAergic drugs in rats. Psychopharmacology, 197 (4). pp. 591-600. ISSN 0033-3158

Mcsheehy, Paul M.J. (2008) Comparison of the effect of patupilone (EPO906) and other cytotoxic drugs on interstitial fluid pressure (IFP) and growth of human ovarian (1A9 and 1A9PTX10) and lung (A549 and A549.B40) xenografts in athymic mice. European Journal of Cancer Supplements, 6 (12). p. 143. ISSN 1359-6349

Mehling, M, Brinkmann, Volker, Antel, J, Bar-Or, A, Goebels, N, Vedrine, Corinne, Kristofic, Colette, Kuhle, J, Lindberg, R L P and Kappos, L (2008) FTY720 therapy exerts differential effects on T cell subsets in multiple sclerosis. Neurology, 71 (16). pp. 1261-1267. ISSN 1526-632X

Mehling, Matthias, Lindberg, Raija L, Kuhle, Jens, Vedrine, Corinne, Kappos, Ludwig and Brinkmann, Volker (2008) Oral fingolimod (FTY720) treatment reduces peripheral IL-17-producing TH17 cells in patients with multiple sclerosis. Multiple Sclerosis, 14 (No 1 Supplement). S234. ISSN 1352-4585

Meng, Lihao, Michaud, Gregory, Merkel, Janie, Zhou, Fang, Huang, Jing, Mattoon, Dawn and Schweitzer, Barry (2008) Protein kinase substrate identification on functional protein arrays. BMC Biotechnology, 8 (1). p. 22. ISSN 1472-6750

Metzler, Barbara, Gfeller, Patrick, Wieczorek, Grazyna and Katopodis, Andreas (2008) Differential promotion of hematopoietic chimerism and inhibition of alloreactive T cell proliferation by combinations of anti-CD40Ligand, anti-LFA-1, everolimus, and deoxyspergualin. Transplant Immunology, 20 (1-2). pp. 106-112. ISSN 0966-3274

Metzler, Barbara, Gfeller, Patrick, Wieczorek, Grazyna, Li, Jianping, Nuesslein-Hildesheim, Barbara, Katopodis, Andreas, Mueller, Matthias and Brinkmann, Volker (2008) Modulation of T cell homeostasis and alloreactivity under continuous FTY720 exposure. International Immunology, 20 (5). pp. 633-644. ISSN 1460-2377

Meyer, Bruno, Freuler, Felix, Guerini, Danilo and Siehler Wagner, Sandra (2008) Reversible translocation of p115-RhoGEF by G(12/13)-coupled receptors. Journal of Cellular Biochemistry, 104 (5). pp. 1660-1670. ISSN 1097-4644

Michel, Monique, Vaxelaire, Juliane, Hattenberger, Marc, Vogelsanger, Melanie, Stauffer, Fabian, Theuer, Andreas, Stephan, Christine, Ito, M and Garcia-Echeverria, Carlos (2008) Assessment of the antitumor activity of NVP-BEZ235 in experimental renal cell carcinoma models. European Journal of Cancer Supplements, 6 (12). p. 71. ISSN 1359-6349

Michishita, Eriko, McCord, Ronald A, Berber, Elisabeth, Kioi, Mitomu, Padilla-Nash, Hesed, Damian, Mara, Cheung, Peggie, Kusumoto, Rika, Kawahara, Tiara L A, Barrett, James, Chang, Howard Y, Bohr, Vilhelm A, Ried, Thomas, Gozani, Or and Chua, Katrin F (2008) SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin. Nature, 452 (7186). pp. 492-496. ISSN 1476-4687

Miller, Todd W, Shin, Incheol, Kagawa, Norio, Evans, Dean Brent, Waterman, Michael R and Arteaga, Carlos L (2008) Aromatase is phosphorylated in situ at serine-118. The Journal of Steroid Biochemistry and Molecular Biology, 112 (1-3). pp. 95-101. ISSN 0960-0760

Miron, Veronique E, Schubart, Anna and Antel, Jack P (2008) Central nervous system-directed effects of FTY720 (fingolimod). Journal of the Neurological Sciences, 274 (1-2). pp. 13-17. ISSN 0022-510X

Mobian, Pierre, Nicolas, Cyril, Francotte, Eric, Buergi, Thomas and Lacour, Jerome (2008) Synthesis, resolution, and VCD analysis of an enantiopure diazaoxatricornan derivative. Journal of the American Chemical Society, 130 (20). pp. 6507-6514. ISSN 1520-5126

Mohn, Fabio, Weber, Michael, Rebhan, Michael, Roloff, Tim C, Richter, Jens, Stadler, Michael B, Bibel, Miriam and Schuebeler, Dirk (2008) Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors. Molecular Cell, 30 (6). pp. 755-766. ISSN 1097-4164

Mosca, F, Tritto, Elaine, Muzzi, A, Monaci, Elisabetta, Bagnoli, Fabio, Iavarone, C, O'Hagan, D, Rappuoli, Rino and De Gregorio, Ennio (2008) Molecular and cellular signatures of human vaccine adjuvants. Proceedings of the National Academy of Sciences of the United States of America, 105 (30). pp. 10501-10506. ISSN 1091-6490

Motzer, Robert J., Escudier, Bernard, Oudard, Stephane, Hutson, Thomas E, Porta, Camillo, Bracarda, Sergio, Gruenwald, Viktor, Thompson, John A, Figlin, Robert A, Hollaender, Norbert, Urbanowitz, Gladys, Berger, Wolfgang, Kay, Andrea, Lebwohl, David and Ravaud, Alain (2008) Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial. Lancet, 372 (9637). pp. 449-456. ISSN 1474-547X

Narendran, Aru, Coppes, Lucas, Jayanthan, Aarthi, Coppes, Michael, Teja, Bijan, Bernoux, Delphine, George, David and Strother, Douglas (2008) Establishment of atypical-teratoid/rhabdoid tumor (AT/RT) cell cultures from disseminated CSF cells: a model to elucidate biology and potential targeted therapeutics. Journal of Neuro-Oncology, 90 (2). pp. 171-180. ISSN 0167-594X

Nigsch, Florian, Bender, Andreas, Jenkins, Jeremy and Mitchell, John B O (2008) Ligand-target prediction using Winnow and naive Bayesian algorithms and the implications of overall performance statistics. Journal of Chemical Information and Modeling, 48 (12). pp. 2313-2325. ISSN 1549-9596

Niikawa, Hiromichi, Suzuki, Takashi, Miki, Yasuhiro, Suzuki, Satoshi, Nagasaki, Shuji, Akahira, Junichi, Honma, Seijiro, Evans, Dean Brent, Hayashi, Shin-Ichi, Kondo, Takashi and Sasano, Hironobu (2008) Intratumoral estrogens and estrogen receptors in human non-small cell lung carcinoma. Clinical Cancer Research : an official journal of the American Association for Cancer Research, 14 (14). pp. 4417-4426. ISSN 1078-0432

Nussbaumer, Peter (2008) Medicinal chemistry aspects of drug targets in sphingolipid metabolism. ChemMedChem, 3 (4). pp. 543-551. ISSN 1860-7187

Nussbaumer, Peter, Hornillos, Valentin, Ghobrial, Michael and Ullrich, Thomas (2008) An efficient, one-pot synthesis of various ceramide 1-phosphates from sphingosine 1-phosphate. Chemistry and Physics of Lipids, 151 (2). pp. 125-128. ISSN 0009-3084

Nussbaumer, Peter, Hornillos Gomez-Recuero, Valentin, Ghobrial, Micha and Ullrich, Thomas (2008) An efficient, one-pot synthesis of various ceramide 1-phosphates from sphingosine 1-phosphate. Chemistry and Physics of Lipids, 151 (2). pp. 125-128. ISSN 0009-3084

Nussbaumer, Peter, Hornillos Gomez-Recuero, Valentin, Ghobrial, Michael and Ullrich, Thomas (2008) An efficient, one-pot synthesis of various ceramide 1-phosphates from sphingosine 1-phosphate. Chemistry and Physics of Lipids, 151 (2). pp. 125-128. ISSN 0009-3084

Obach, R Scott, Lombardo, Franco and Waters, Nigel (2008) Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug Metabolism and Disposition: the biological fate of chemicals, 36 (7). pp. 1385-1405. ISSN 1521-009X

Ong, Swee Hoe, Yip, Jin Teen, Chen, Yen Liang, Liu, Wei, Harun, Syahrial, Lystiyaningsih, Erlin, Heriyanto, Bambang, Beckett, Charmagne G, Mitchell, Wayne P, Hibberd, Martin L, Suwandono, Agus, Vasudevan, Subhash and Schreiber, Mark (2008) Periodic re-emergence of endemic strains with strong epidemic potential-a proposed explanation for the 2004 Indonesian dengue epidemic. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 8 (2). pp. 191-204. ISSN 1567-1348

Osborn, O, Brownell, S E, Sanchez-Alavez, M, Salomon, D, Gram, Hermann and Bartfai, T (2008) Treatment with an Interleukin 1 beta antibody improves glycemic control in diet-induced obesity. Cytokine, 44 (1). pp. 141-148. ISSN 1096-0023

Osborn, Olivia, Gram, Hermann, Zorrilla, Eric P, Conti, Bruno and Bartfai, Tamas (2008) Insights into the roles of the inflammatory mediators IL-1, IL-18 and PGE2 in obesity and insulin resistance. Swiss Medical Weekly : official journal of the Swiss Society of Infectious Diseases, the Swiss Society of Internal Medicine, the Swiss Society of Pneumology, 138 (45-46). pp. 665-673. ISSN 1424-7860

Park, Boyoun, Brinkmann, Melanie M, Spooner, Eric, Lee, Clarissa C, Kim, You-Me and Ploegh, Hidde L (2008) Proteolytic cleavage in an endolysosomal compartment is required for activation of Toll-like receptor 9. Nature Immunology, 9 (12). pp. 1407-1414. ISSN 1529-2916

Pauchard, Yves, Mattmann, Corinne, Kuhn, Andreas, Gasser, Juerg Andreas and Boyd, Steven K (2008) European Society of Biomechanics S.M. Perren Award 2008: using temporal trends of 3D bone micro-architecture to predict bone quality. Journal of Biomechanics, 41 (14). pp. 2946-2953. ISSN 0021-9290

Peukert, Stefan, Sun, Yingchuan, Zhang, Rui, Hurley, Brian, Sabio, Michael, Shen, Xiaoyu, Gray, Christen, Dzink-Fox, Joann, Tao, Jianshi, Cebula, Regina and Wattanasin, Sompong (2008) Design and structure-activity relationships of potent and selective inhibitors of undecaprenyl pyrophosphate synthase (UPPS): tetramic, tetronic acids and dihydropyridin-2-ones. Bioorganic & Medicinal Chemistry Letters, 18 (6). pp. 1840-1844. ISSN 1464-3405

Piao, Wenhua, Wang, Yu, Adachi, Yasushi, Yamamoto, Hiroyuki, Li, Rong, Imsumran, Arisa, Li, Hua, Maehata, Tadateru, Ii, Masanori, Arimura, Yoshiaki, Lee, Choon-Taek, Shinomura, Yasuhisa, Carbone, David P and Imai, Kohzoh (2008) Insulin-like growth factor-I receptor blockade by a specific tyrosine kinase inhibitor for human gastrointestinal carcinomas. Molecular cancer therapeutics, 7 (6). pp. 1483-1493. ISSN 1535-7163

Pichota, Arkadius, Duraiswamy, Jeyaraj, Yin, Zheng, Keller, Thomas, Alam, Jenefer, Liung, Sarah, Lee, Gladys, Ding, Mei, Wang, Gang, Chan, Wai Ling, Schreiber, Mark, Ma, Ida, Beer, David, Ngew, Xinyi, Mukherjee, Kakoli, Nanjundappa, Mahesh, Teo, Jeanette, Thayalan, Pamela, Yap, Amelia, Dick, Thomas, Meng, Wuyi, Xu, Mei, Koehn, James, Pan, Shihao, Clark, Kirk, Xie, Xiaoling, Shoen, Carolyn and Cynamon, Michael (2008) Peptide deformylase inhibitors of Mycobacterium tuberculosis: synthesis, structural investigations, and biological results. Bioorganic & Medicinal Chemistry Letters, 18 (24). pp. 6568-6572. ISSN 0960-894X

Prathipati, Philip, Ma, Ngai Ling and Keller, Thomas (2008) Global bayesian models for the prioritization of antitubercular agents. Journal of Chemical Information and Modeling, 48 (12). pp. 2362-2370. ISSN 1549-9596

Previte, Michael J R, Peler, Serge, Kim, Ki Hean, Buehler, Christof and So, Peter T C (2008) Spectrally resolved fluorescence correlation spectroscopy based on global analysis. Analytical Chemistry, 80 (9). pp. 3277-3284. ISSN 1520-6882

Pryce, Christopher (2008) Postnatal ontogeny of expression of the corticosteroid receptor genes in mammalian brains: inter-species and intra-species differences. Brain Research Reviews, 57 (2). pp. 596-605. ISSN 0165-0173

Puschendorf, Mareike, Terranova, Remi, Boutsma, Erwin, Mao, Xiaohong, Isono, Kyo-ichi, Brykczynska, Urszula, Kolb, Carolin, Otte, Arie P, Koseki, Haruhiko, Orkin, Stuart H, van Lohuizen, Maarten and Peters, Antoine (2008) PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos. Nature Genetics, 40 (4). pp. 411-420. ISSN 1546-1718

Qing, Hong, He, Guiqiong, Ly, Philip T T, Fox, Christopher J, Staufenbiel, Matthias, Cai, Fang, Zhang, Zhuohua, Wei, Shengcai, Sun, Xiulian, Chen, Chia-Hsiung, Zhou, Weihui, Wang, Ke and Song, Weihong (2008) Valproic acid inhibits Abeta production, neuritic plaque formation, and behavioral deficits in Alzheimer's disease mouse models. The Journal of Experimental Medicine, 205 (12). pp. 2781-2789. ISSN 1540-9538

Rao, Srinivasa, Alonso, Sylvie, Rand, Lucinda, Dick, Thomas and Pethe, Kevin (2008) The protonmotive force is required for maintaining ATP homeostasis and viability of hypoxic, nonreplicating Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America, 105 (33). pp. 11945-11950. ISSN 1091-6490

Rao, Srinivasa, Camacho, Luis, Tan, Bee Huat, Boon, Calvin, Russel, David G, Dick, Thomas and Pethe, Kevin (2008) Recombinase-based reporter system and antisense technology to study gene expression and essentiality in hypoxic nonreplicating mycobacteria. FEMS Microbiology Letters, 284 (1). pp. 68-75. ISSN 0378-1097

Rennard, Stephen, Bantje, Theo, Centanni, Stefano, Chanez, Pascal, Chuchalin, Alexander, D'Urzo, Anthony, Kornmann, Oliver, Perry, Sheryl, Jack, Damon, Owen, Roger and Higgins, Mark (2008) A dose-ranging study of indacaterol in obstructive airways disease, with a tiotropium comparison. Respiratory Medicine, 102 (7). pp. 1033-1044. ISSN 0954-6111

Ribrioux, Sebastien, Brüngger, Adrian, Baumgarten, Birgit, Seuwen, Klaus and John, Markus (2008) Bioinformatics prediction of overlapping frameshifted translation products in mammalian transcripts. BMC Genomics, 9 (1). p. 122. ISSN 1471-2164

Ribrioux, Sebastien, Brungger, Adrian, Baumgarten, Birgit, Seuwen, Klaus and John, Markus (2008) Bioinformatics prediction of overlapping frameshifted translation products in mammalian transcripts. BMC Genomics, 9. p. 122. ISSN 1471-2164

Rines, Daniel, Gomez-Ferreira, Maria Ana, Zhou, Yingyao, De Jesus, Paul, Grob, Seanna, Batalov, Sergei, Labow, Mark, Huesken, Dieter, Mickanin, Craig, Hall, Jonathan, Reinhardt, Mischa, Natt, Francois, Lange, Joerg, Sharp, David J, Chanda, Sumit and Caldwell, Jeremy (2008) Whole genome functional analysis identifies novel components required for mitotic spindle integrity in human cells. Genome Biology, 9 (2). R44. ISSN 1465-6914

Rines, Daniel R, Gomez-Ferreria, Maria Ana, Zhou, Yingyao, DeJesus, Paul, Grob, Seanna, Batalov, Serge, Labow, Mark, Huesken, Dieter, Mickanin, Craig, Hall, Jonathan, Reinhardt, Mischa, Natt, Francois, Lange, Joerg, Sharp, David J, Chanda, Sumit K and Caldwell, Jeremy S (2008) Whole genome functional analysis identifies novel components required for mitotic spindle integrity in human cells. Genome biology, 9 (2). R44. ISSN 1465-6914

Ritter, Veronique O., Thuering, Barbara, Saint-Mezard, Pierre, Luong-Nguyen, Ngoc-Hong, Seltenmeyer, Yves, Junker, Uwe, Fournier, Brigitte, Susa Spring, Mira and Morvan, Frederic (2008) Follicle-stimulating hormone does not impact male bone mass in vivo or human male osteoclasts in vitro. Calcified Tissue International, 82 (5). pp. 383-391. ISSN 0171-967X

Rockx, Barry, Corti, Davide, Donaldson, Eric, Sheahan, Timothy, Stadler, Konrad, Lanzavecchia, Antonio and Baric, Ralph (2008) Structural basis for potent cross-neutralizing human monoclonal antibody protection against lethal human and zoonotic severe acute respiratory syndrome coronavirus challenge. Journal of Virology, 82 (7). pp. 3220-3235. ISSN 1098-5514

Rooks, Daniel (2008) Talking to patients with fibromyalgia about physical activity and exercise. Current Opinion in Rheumatology, 20 (2). pp. 208-212. ISSN 1040-8711

Rucci, Nadia, Susa, Maria and Teti, Anna (2008) Inhibition of protein kinase c-Src as a therapeutic approach for cancer and bone metastases. Anti-cancer Agents in Medicinal Chemistry, 8 (3). pp. 342-349. ISSN 1871-5206

Russell, Colin A, Jones, Terri, Barr, Ian G, Cox, Nancy J, Garten, Rebecca J, Gregory, Vicky, Gust, Ian D, Hampson, Alan W, Hay, Alan J, Hurt, Aeron C, de Jong, Jan C, Kelso, Anne, Klimov, Alexander I, Kageyama, Tsutomu, Komadina, Naomi, Lapedes, Alan S, Lin, Yi P, Mosterin, Ana, Obuchi, Masatsugu, Odagiri, Takato, Osterhaus, Albert D M E, Rimmelzwaan, Guus F, Shaw, Michael W, Skepner, Eugene, Stohr, Klaus, Tashiro, Masato, Fouchier, Ron A M and Smith, Derek J (2008) The global circulation of seasonal influenza A (H3N2) viruses. Science (New York, N.Y.), 320 (5874). pp. 340-346. ISSN 1095-9203

Rutjens, Erik, Vermeulen, Joost, Verstrepen, Babs, Hofman, Sam, Prins, Jan M, Srivastava, Indresh, Heeney, Jonathan L and Koopman, Gerrit (2008) Chimpanzee CD4+ T cells are relatively insensitive to HIV-1 envelope-mediated inhibition of CD154 up-regulation. European Journal of Immunology, 38 (4). pp. 1164-1172. ISSN 0014-2980

Salie, Rishard, Li, Haitao, Jiang, Xi, Rowe, David W, Kalajzic, Ivo and Susa Spring, Mira (2008) A rapid, nonradioactive in situ hybridization technique for use on cryosectioned adult mouse bone. Calcified Tissue International, 83 (3). pp. 212-221. ISSN 0171-967X

Sari-Sarraf, Farid, Pomposiello, Silvia and Laurent, Didier (2008) Acute impairment of rat renal function by L -NAME as measured using dynamic MRI. Magnetic Resonance Materials in Physics, Biology and Medicine, 21 (4). pp. 291-297. ISSN 0968-5243

Sato, Hiroyasu, Kato, Rina, Isogai, Yuki, Saka, Go-ichi, Ohtsuki, Mitsuhiro, Taketomi, Yoshitaka, Yamamoto, Kei, Tsutsumi, Kae, Yamada, Joe, Masuda, Seiko, Ishikawa, Yukio, Ishii, Toshiharu, Kobayashi, Tetsuyuki, Ikeda, Kazutaka, Taguchi, Ryo, Hatakeyama, Shinji, Hara, Shuntaro, Kudo, Ichiro, Itabe, Hiroyuki and Murakami, Makoto (2008) Analyses of group III secreted phospholipase A2 transgenic mice reveal potential participation of this enzyme in plasma lipoprotein modification, macrophage foam cell formation, and atherosclerosis. The Journal of Biological Chemistry, 283 (48). pp. 33483-33497. ISSN 0021-9258

Saul, Allan and Rappuoli, Rino (2008) The Novartis Vaccines Institute for Global Health: a new initiative for developing vaccines for neglected diseases in developing countries. Journal of Infection in Developing Countries, 2 (2). pp. 154-155. ISSN 1972-2680

Savage, Ronald E, Tyler, Andrew, Miao, Xiu-Sheng and Chan, Thomas C K (2008) Identification of a novel glucosylsulfate conjugate as a metabolite of 3,4-dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione (ARQ 501, beta-lapachone) in mammals. Drug Metabolism and Disposition: the biological fate of chemicals, 36 (4). pp. 753-758. ISSN 1521-009X

Schedlbauer, Andreas, Auer, Renate, Ledolter, Karin, Tollinger, Martin, Kloiber, Karin, Lichtenecker, Roman, Ruedisser, Simon, Hommel, Ulrich, Schmid, Walther, Konrat, Robert and Kontaxis, Georg (2008) Direct methods and residue type specific isotope labeling in NMR structure determination and model-driven sequential assignment. Journal of Biomolecular NMR, 42 (2). pp. 111-127. ISSN 0925-2738

Scheiber, Josef, Jenkins, Jeremy, Bender, Andreas, Whitebread, Steven, Hamon, Jacques, Urban, Laszlo, Azzaoui, Kamal, Glick, Meir and Davies, John (2008) Side effect profile prediction - early addressing of big pharma's worst nightmare. Chemistry Central Journal, 2 (Suppl ). S4. ISSN 1752-153X

Schindeler, Aaron, Morse, Alyson, Harry, Lorraine, Godfrey, Craig, Mikulec, Kathy, McDonald, Michelle, Gasser, Juerg Andreas and Little, David G (2008) Models of tibial fracture healing in normal and Nf1-deficient mice. Journal of Orthopaedic Research : official publication of the Orthopaedic Research Society, 26 (8). pp. 1053-1060. ISSN 1554-527X

Schlapbach, Achim, Feifel, Roland, Hawtin, Stuart, Heng, Richard, Koch, Guido, Moebitz, Henrik, Revesz, Laszlo, Scheufler, Clemens, Velcicky, Juraj, Waelchli, Rudolf and Huppertz, Christine (2008) Pyrrolo-pyrimidones: a novel class of MK2 inhibitors with potent cellular activity. Bioorganic & Medicinal Chemistry Letters, 18 (23). pp. 6142-6146. ISSN 1464-3405

Schmid, Herbert (2008) Pasireotide (SOM230): Development, mechanism of action and potential applications. Molecular and Cellular Endocrinology, 286 (1-2). pp. 69-74. ISSN 0303-7207

Schmid, Ralf, Tsujimoto, Naomi, Qu, Qiang, Lei, Hong, Li, En, Chen, Taiping and Blaustein, Cecile (2008) A methyl-CpG-binding protein 2-enhanced green fluorescent protein reporter mouse model provides a new tool for studying the neuronal basis of Rett syndrome. Neuroreport, 19 (4). pp. 393-398. ISSN 0959-4965

Schmid, Ralf S, Tsujimoto, Naomi, Qu, Qiang, Lei, Hong, Li, En, Chen, Taiping and Blaustein, Cecile (2008) A methyl-CpG-binding protein 2-enhanced green fluorescent protein reporter mouse model provides a new tool for studying the neuronal basis of Rett syndrome. Neuroreport, 19 (4). pp. 393-398. ISSN 0959-4965

Schrenk-Siemens, Katrin, Perez-Alcala, Siro, Richter, Jens, Lacroix, Emmanuel, Rahuel, Joseph, Korte, Martin, Müller, Ulrike, Barde, Yves-Alain and Bibel, Miriam (2008) Embryonic stem cell-derived neurons as a cellular system to study gene function: lack of amyloid precursor proteins APP and APLP2 leads to defective synaptic transmission. Stem Cells (Dayton, Ohio), 26 (8). pp. 2153-2163. ISSN 1549-4918

Schubart, Anna, Seabrook, Tim, Rausch, Martin and Mir, Anis Khusro (2008) Oral fingolimod (FTY720) suppresses established EAE and allows remyelination. Journal of Neuroimmunology, 203 (2). p. 248. ISSN 0165-5728

Scuto, Anna, Kirschbaum, Mark, Kowolik, Claudia, Kretzner, Leo, Juhasz, Agnes, Atadja, Paul, Pullarkat, Vinod, Bhatia, Ravi, Forman, Stephen, Yen, Yun and Jove, Richard (2008) The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph- acute lymphoblastic leukemia cells. Blood, 111 (10). pp. 5093-5100. ISSN 1528-0020

Sechaud, R, Robeva, A, Belleli, R and Balez, S (2008) Absence of an effect of a single-dose deferasirox on the steady-state pharmacokinetics of digoxin. International journal of clinical pharmacology and therapeutics, 46 (10). pp. 519-526. ISSN 0946-1965

Sechaud, Romain, Robeva, Anna, Belleli, Rossella and Balez, Sebastien (2008) Absence of an effect of a single-dose deferasirox on the steady-state pharmacokinetics of digoxin. International journal of clinical pharmacology and therapeutics, 46 (10). pp. 519-526. ISSN 0946-1965

Sechaud, Romain, Robeva, Anna, Belleli, Rossella and Balez, Sebastien (2008) Absolute oral bioavailability and disposition of deferasirox in healthy human subjects. Journal of clinical pharmacology, 48 (8). pp. 919-925. ISSN 0091-2700

Senechal, Yann, Kelly, Peter and Dev, Kumlesh K. (2008) Amyloid precursor protein knockout mice show age-dependent deficits in passive avoidance learning. Behavioural Brain Research, 186 (1). pp. 126-132. ISSN 0166-4328

Senechal, Yann, Prut, Laetitia, Kelly, Peter, Staufenbiel, Matthias, Natt, Francois, Hoyer, Daniel, Wiessner, Christoph and Dev, Kumlesh K. (2008) Increased exploratory activity of APP23 mice in a novel environment is reversed by siRNA. Brain Research, 1243. pp. 124-133. ISSN 1872-6240

Serluca-Aegerter, Fabrizio (2008) Development of the proepicardial organ in the zebrafish. Developmental Biology, 315 (1). pp. 18-27. ISSN 1095-564X

Serra, Alessandro, Nuti, Sandra, Tavarini, Simona, Sammicheli, Chiara, Rosa, Domenico, Saletti, Giulietta, Soldaini, Elisabetta, Abrignani, Sergio and Wack, Andreas (2008) Coligation of the hepatitis C virus receptor CD81 with CD28 primes naive T lymphocytes to acquire type 2 effector function. Journal of Immunology (Baltimore, Md. : 1950), 181 (1). pp. 174-185. ISSN 0022-1767

Serra, Violeta, Markman, Ben, Scaltriti, Maurizio, Eichhorn, Pieter J A, Valero, Vanesa, Guzman, Marta, Botero, Maria Luisa, Llonch, Elisabeth, Atzori, Francesco, Di Cosimo, Serena, Maira, Michel, Garcia-Echeverria, Carlos, Parra, Josep Lluis, Arribas, Joaquin and Baselga, José (2008) NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations. Cancer Research, 68 (19). pp. 8022-8030. ISSN 1538-7445

Seubert, Anja, Monaci, Elisabetta, Pizza, Mariagrazia, O'Hagan, Derek T and Wack, Andreas (2008) The adjuvants aluminum hydroxide and MF59 induce monocyte and granulocyte chemoattractants and enhance monocyte differentiation toward dendritic cells. Journal of Immunology (Baltimore, Md. : 1950), 180 (8). pp. 5402-5412. ISSN 0022-1767

Shah, J Jina, Maloney, Susan A, Liu, Yecai, Flagg, Elaine W, Johnston, Stephanie P, Young, Suzanna A, Weston, Robert, Merritt, Samuel, Wilkins, Patricia P, Keane, Vincent, Calderon, Jaime, Sharp, Donald J, Causer, Louise, Maguire, James H and Cetron, Martin S (2008) Evaluation of the impact of overseas pre-departure treatment for infection with intestinal parasites among Montagnard refugees migrating from Cambodia to North Carolina. The American Journal of Tropical Medicine and Hygiene, 78 (5). pp. 754-759. ISSN 1476-1645

Shao, Wenlin, Growney, Joseph, O'Connor, Gregory, Feng, Yun, Scher, H, Yao, Yao, Fawell, Stephen and Atadja, Peter (2008) Potent anticancer activity of panobinostat (LBH589) in models of hormone-refractory prostate cancer (HRPC): targeting the androgen receptor. European Journal of Cancer Supplements, 6 (12). p. 52. ISSN 1359-6349

Shen, Xiaohua, Liu, Yingchun, Hsu, Yu-Jung, Fujiwara, Yuko, Kim, Jonghwan, Mao, Xiaohong, Yuan, Guo-Cheng and Orkin, Stuart H (2008) EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency. Molecular cell, 32 (4). pp. 491-502. ISSN 1097-4164

Shi, Leming, Jones, Wendell, Jensen, Roderick, Harris, Stephen, Perkins, Roger, Goodsaid, Federico, Guo, Lei, Croner, Lisa, Boysen, Cecilie, Fang, Hong, Qian, Feng, Amur, Shashi, Bao, Wenjun, Barbacioru, Catalin, Bertholet, Vincent, Cao, Xiaoxi, Chu, Tzu-Ming, Collins, Patrick, Fan, Xiao-hui, Frueh, Felix, Fuscoe, James, Han, jing, Guo, Xu, Herman, Damir, Hong, Huixiao, Kawasaki, Ernest, Li, Quan-Zhen, Luo, Yuling, Ma, Yunqing, Mei, Nan, Peterson, Ron and Puri, Raj (2008) The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies. BMC Bioinformatics, 9 (Suppl ). S10. ISSN 1471-2105

Shibui, Takeo, Higo, Yukari, Tsutsui, Takeo W, Uchida, Minoru, Oshimura, Mitsuo, Barrett, James and Tsutsui, Takeki (2008) Changes in expression of imprinted genes following treatment of human cancer cell lines with non-mutagenic or mutagenic carcinogens. International Journal of Oncology, 33 (2). pp. 351-360. ISSN 1019-6439

Shua-Haim, Joshua, Smith, Juanita, Picard, Franck, Sedek, Greg, Athalye, Sandeep, Pommier, Françoise and Lefevre, Gilbert (2008) Steady-state pharmacokinetics of rivastigmine in patients with mild to moderate Alzheimer's disease not affected by co-administration of memantine: an open-label, crossover, single-centre study. Clinical drug investigation, 28 (6). pp. 361-374. ISSN 1173-2563

Siegl, Stephanie, Flor, Peter Josef and Fendt, Markus (2008) Amygdaloid metabotropic glutamate receptor subtype 7 is involved in the acquisition of conditioned fear. Neuroreport, 19 (11). pp. 1147-1150. ISSN 0959-4965

Siehler Wagner, Sandra (2008) Cell-based assays in GPCR drug discovery. Biotechnology Journal, 3 (4). pp. 471-483. ISSN 1860-7314

Siehler Wagner, Sandra, Nunn, Caroline, Hannon, Jason, Feuerbach, Dominik and Hoyer, Daniel (2008) Pharmacological profile of somatostatin and cortistatin receptors. Molecular and Cellular Endocrinology, 286 (1-2). pp. 26-34. ISSN 0303-7207

Simonen, Marjo, Ibig-Rehm, Yvonne, Hofmann, Gabriele, Zimmermann, Johann, Albrecht, Genevieve, Magnier, Maxime, Heidinger-Millot, Valerie and Gabriel, Daniela (2008) High-content assay to study protein prenylation. Journal of Biomolecular Screening : the official journal of the Society for Biomolecular Screening, 13 (6). pp. 456-467. ISSN 1087-0571

Skaanderup, Philip and Jensen, Thomas (2008) Synthesis of the macrocyclic core of (-)-pladienolide B. Organic Letters, 10 (13). pp. 2821-2824. ISSN 1523-7060

Song, Pingfang, Sekhon, Harmanjatinder S, Fu, Xiao Wen, Maier, Michelle, Jia, Yibing, Duan, Jie, Proskosil, Becky J, Gravett, Courtney, Lindstrom, Jon, Mark, Gregory P, Saha, Saurabh and Spindel, Eliot R (2008) Activated cholinergic signaling provides a target in squamous cell lung carcinoma. Cancer Research, 68 (12). pp. 4693-4700. ISSN 1538-7445

Soon, E, Holmes, Alan, Toshner, M, Treacy, C, Suntharalingam, J, Sheares, K, Budd, David, Pepke-Zaba, J and Morrell, N W (2008) Circulating Cytoking Profiles in Patients with Chronic Thromboembolic Pulmonary Hypertension and Response to Pulmonary Endarterectomy. Thorax, 63 (Supplement 7). A43. ISSN 0040-6376

Srivastava, Indresh K, Kan, Elaine, Sun, Yide, Sharma, Victoria A, Cisto, Jimna, Burke, Brian, Lian, Ying, Hilt, Susan, Biron, Zohar, Hartog, Karin, Stamatatos, Leonidas, Diaz-Avalos, Ruben, Cheng, R Holland, Ulmer, Jeffrey and Barnett, Susan W (2008) Comparative evaluation of trimeric envelope glycoproteins derived from subtype C and B HIV-1 R5 isolates. Virology, 372 (2). pp. 273-290. ISSN 0042-6822

Stansfeld, Phillip J, Grottesi, Alessandro, Sands, Zara A, Sansom, Mark S P, Gedeck, Peter, Gosling, Martin, Cox, Brian, Stanfield, Peter R, Mitcheson, John S and Sutcliffe, Michael J (2008) Insight into the mechanism of inactivation and pH sensitivity in potassium channels from molecular dynamics simulations. Biochemistry, 47 (28). pp. 7414-7422. ISSN 1520-4995

Stauffer, Frederic, Maira, Sauveur-Michel, Furet, Pascal and Garcia-Echeverria, Carlos (2008) Imidazo[4,5-c]quinolines as inhibitors of the PI3K/PKB-pathway. Bioorganic & Medicinal Chemistry Letters, 18 (3). pp. 1027-1030. ISSN 1464-3405

Stauffer, Frederic, Maira, Sauveur-Michel, Furet, Pascal and García-Echeverría, Carlos (2008) Imidazo[4,5-c]quinolines as inhibitors of the PI3K/PKB-pathway. Bioorganic & Medicinal Chemistry Letters, 18 (3). pp. 1027-3100. ISSN 1464-3405

Stickings, Paul, Peyre, Marisa, Coombes, Laura, Muller, Sylviane, Rappuoli, Rino, Del Giudice, Giuseppe, Partidos, Charalambos D and Sesardic, Dorothea (2008) Transcutaneous immunization with cross-reacting material CRM(197) of diphtheria toxin boosts functional antibody levels in mice primed parenterally with adsorbed diphtheria toxoid vaccine. Infection and Immunity, 76 (4). pp. 1766-1773. ISSN 1098-5522

Stringer, Rowan, Nicklin, Paul and Houston, J B (2008) Reliability of human cryopreserved hepatocytes and liver microsomes as in vitro systems to predict metabolic clearance. Xenobiotica, 38 (10). pp. 1313-1329. ISSN 1366-5928

Sullivan, David and Martin, Eric (2008) Exploiting structure-activity relationships in docking. Journal of Chemical Information and Modeling, 48 (4). pp. 817-830. ISSN 1549-9596

Sullivan-Brown, Jessica, Schottenfeld, Jodi, Okabe, Noriko, Hostetter, Christine L, Serluca-Aegerter, Fabrizio, Thiberge, Stephan Y and Burdine, Rebecca D (2008) Zebrafish mutations affecting cilia motility share similar cystic phenotypes and suggest a mechanism of cyst formation that differs from pkd2 morphants. Developmental Biology, 314 (2). pp. 261-275. ISSN 1095-564X

Sumby, Paul, Zhang, Shizhen, Whitney, Adeline R, Falugi, Fabiana, Grandi, Guido, Graviss, Edward A, Deleo, Frank R and Musser, James M (2008) A chemokine-degrading extracellular protease made by group A Streptococcus alters pathogenesis by enhancing evasion of the innate immune response. Infection and immunity, 76 (3). pp. 978-985. ISSN 1098-5522

Séchaud, R, Dutreix, C, Balez, S, Pommier, F, Dumortier, T, Morisson, S and Brun, E (2008) Relative bioavailability of deferasirox tablets administered without dispersion and dispersed in various drinks. International journal of clinical pharmacology and therapeutics, 46 (2). pp. 102-108. ISSN 0946-1965

Takahashi, Nozomi, de Jager, Victor C L, Glueck, Anton, Letzkus, Martin, Hartmann, Nicole, Staedtler, Frank, Ribeiro-Dias, Fatima, Heuvelmans-Jacobs, Marleen, van den Berg, Wim B and Joosten, Leo A B (2008) The molecular signature of oxidative metabolism and the mode of macrophage activation determine the shift from acute to chronic disease in experimental arthritis: critical role of interleukin-12p40. Arthritis and Rheumatism, 58 (11). pp. 3471-3484. ISSN 0004-3591

Tanner, Lukas, Schreiber, Mark, Low, Jenny, Ong, Adrian, Tolfvenstam, Thomas, Lai, Yee Ling, Ng, Lee Ching, Leo, Yee Sin, Thi Puong, Le, Vasudevan, Subhash, Simmons, Cameron P, Hibberd, Martin L and Ooi, Eng Eong (2008) Decision tree algorithms predict the diagnosis and outcome of dengue Fever in the early phase of illness. PLoS Neglected Tropical Diseases, 2 (3). e196. ISSN 1935-2735

Telford, John L (2008) Bacterial genome variability and its impact on vaccine design. Cell host & Microbe, 3 (6). pp. 408-416. ISSN 1934-6069

Tengvall, Sara, O'Hagan, Derek and Harandi, Ali M (2008) Rectal immunization generates protective immunity in the female genital tract against herpes simplex virus type 2 infection: relative importance of myeloid differentiation factor 88. Antiviral Research, 78 (3). pp. 202-214. ISSN 0166-3542

Teno, Naoki, Irie, Osamu, Miyake, Takahiro, Gohda, Keigo, Horiuchi, Miyuki, Tada, Sachiyo, Nonomura, Kazuhiko, Kometani, Motohiko, Iwasaki, Genji and Betschart, Claudia (2008) New chemotypes for cathepsin K inhibitors. Bioorganic & Medicinal Chemistry Letters, 18 (8). pp. 2599-2603. ISSN 1464-3405

Thoma, Gebhard, Beerli, Christian, Bigaud, Marc, Bruns, Christian, Cooke, Nigel Graham, Streiff, Markus and Zerwes, Hans-Guenter (2008) Reduced cardiac side-effect potential by introduction of polar groups: discovery of NIBR-1282, an orally bioavailable CCR5 antagonist which is active in vivo. Bioorganic & Medicinal Chemistry letters, 18 (6). pp. 2000-2005. ISSN 1464-3405

Thoma, Gebhard, Streiff, Markus, Kovarik, Jiri, Glickman, Fraser, Wagner, Beatrix, Beerli, Christian and Zerwes, Hans-Guenter (2008) Orally bioavailable isothioureas block function of the chemokine receptor CXCR4 in vitro and in vivo. Journal of Medicinal Chemistry, 51 (24). pp. 7915-7920. ISSN 1520-4804

Thomas, Matthew and Owen, Charles (2008) Inhibition of PI-3 kinase for treating respiratory disease: good idea or bad idea? Current Opinion in Pharmacology, 8 (3). pp. 267-274. ISSN 1471-4892

Tiao, Jim Yu-Hsiang, Bradaia, Amyaouch, Biermann, Barbara, Kaupmann, Klemens, Metz, Michaela, Haller, Corinne, Rolink, Antonius G, Pless, Elin, Barlow, Paul N, Gassmann, Martin and Bettler, Bernhard (2008) The sushi domains of secreted GABA(B1) isoforms selectively impair GABA(B) heteroreceptor function. The Journal of Biological Chemistry, 283 (45). pp. 31005-31011. ISSN 0021-9258

Titz, Alexander, Patton, John, Alker, Andre M, Porro, Michele, Schwardt, Oliver Roland, Hennig, Michael, Francotte, Eric, Magnani, John L. and Ernst, Beat (2008) Is adamantane a suitable substituent to pre-organize the acid orientation in E-selectin antagonists? Bioorganic & Medicinal Chemistry, 16 (2). pp. 1046-1056. ISSN 1464-3391

Titz, Alexander, Patton, John, Alker, André M, Porro, Michele, Schwardt, Oliver, Hennig, Michael, Francotte, Eric, Magnani, John and Ernst, Beat (2008) Is adamantane a suitable substituent to pre-organize the acid orientation in E-selectin antagonists? Bioorganic & Medicinal Chemistry, 16 (2). pp. 1046-1056. ISSN 1464-3391

Troxler, Thomas J., Enz, Albert, Hoyer, Daniel, Langenegger, Daniel, Neumann, Peter, Pfaeffli, Paul, Schoeffter, Philippe and Hurth, Konstanze (2008) Ergoline derivatives as highly potent and selective antagonists at the somatostatin sst 1 receptor. Bioorganic & Medicinal Chemistry Letters, 18 (3). pp. 979-982. ISSN 1464-3405

Umareddy, Indira, Tang, Kin Fai, Vasudevan, Subhash, Devi, Shamala, Hibberd, Martin L and Gu, Feng (2008) Dengue virus regulates type I interferon signalling in a strain-dependent manner in human cell lines. The Journal of General Virology, 89 (Pt 12). pp. 3052-3062. ISSN 0022-1317

Vajpai, Navratna, Strauss, Andre, Fendrich, Gabriele, Jacob, Sandra, Manley, Paul W., Grzesiek, Stephan and Jahnke, Wolfgang (2008) Solution conformations and dynamics of ABL kinase-inhibitor complexes determined by NMR substantiate the different binding modes of imatinib/nilotinib and dasatinib. The Journal of biological chemistry, 283 (26). pp. 18292-18302. ISSN 0021-9258

Van Dijck, Annemie, Vloeberghs, Ellen, Van Dam, Debby, Staufenbiel, Matthias and De Deyn, Peter Paul (2008) Evaluation of the APP23-model for Alzheimer's disease in the odour paired-associate test for hippocampus-dependent memory. Behavioural Brain Research, 190 (1). pp. 147-151. ISSN 0166-4328

Van Eis, Maurice, BICKELHAUPT, M, VANLOON, S, LUTZ, M, SPEK, A, DEWOLF, W, VAN ZEIST, W and BICKELHAUPT, F (2008) Tricarbonylchromium complexes of [5]- and [6]metacyclophane: an experimental and theoretical study. Tetrahedron, 64 (51). pp. 11641-11646. ISSN 0040-4020

Vanoni, Omar, Paganetti, Paolo and Molinari, Maurizio (2008) Consequences of individual N-glycan deletions and of proteasomal inhibition on secretion of active BACE. Molecular Biology of the Cell, 19 (10). pp. 4086-4098. ISSN 1939-4586

Verheul, Henk M W, Salumbides, Brenda, Van Erp, Karen, Hammers, Hans, Qian, David Z, Sanni, Tolib, Atadja, Peter and Pili, Roberto (2008) Combination strategy targeting the hypoxia inducible factor-1 alpha with mammalian target of rapamycin and histone deacetylase inhibitors. Clinical Cancer Research: an official journal of the American Association for Cancer Research, 14 (11). pp. 3589-3597. ISSN 1078-0432

Vlkolinsky, Roman, Krucker, Thomas, Nelson, Gregory A and Obenaus, Andre (2008) (56)Fe-particle radiation reduces neuronal output and attenuates lipopolysaccharide-induced inhibition of long-term potentiation in the mouse hippocampus. Radiation Research, 169 (5). pp. 523-530. ISSN 0033-7587

Wang, Biao, Goode, Jason, Best, Jennifer, Meltzer, Jodi, Schilman, Pablo E, Chen, Jian, Garza, Dan, Thomas, John B and Montminy, Marc (2008) The insulin-regulated CREB coactivator TORC promotes stress resistance in Drosophila. Cell Metabolism, 7 (5). pp. 434-444. ISSN 1932-7420

Wang, Zhi Gang, Fukazawa, Takuya, Nishikawa, Toshio, Watanabe, Nobuyuki, Sakurama, Kazufumi, Motoki, Takayuki, Takaoka, Munenori, Hatakeyama, Shinji, Omori, Osamu, Ohara, Toshiaki, Tanabe, Shunsuke, Fujiwara, Yasuhiro, Shirakawa, Yasuhiro, Yamatsuji, Tomoki, Tanaka, Noriaki and Naomoto, Yoshio (2008) TAE226, a dual inhibitor for FAK and IGF-IR, has inhibitory effects on mTOR signaling in esophageal cancer cells. Oncology Reports, 20 (6). pp. 1473-1477. ISSN 1021-335X

Wang, Ling, Montano, Monty, Rarick, Matt and Sebastiani, Paola (2008) Conditional clustering of temporal expression profiles. BMC Bioinformatics, 9. p. 147. ISSN 1471-2105

Wannier-Morino, P, Schmidlin, E, Freund, P, Belhaj-Saif, A, Bloch, J, Mir, Anis Khusro, Schwab, M E, Rouiller, E M and Wannier, T (2008) Fate of rubrospinal neurons after unilateral section of the cervical spinal cord in adult macaque monkeys: effects of an antibody treatment neutralizing Nogo-A. Brain Research, 1217. pp. 96-109. ISSN 0006-8993

Watanabe, Nobuyuki, Takaoka, Munenori, Sakurama, Kazufumi, Tomono, Yasuko, Hatakeyama, Shinji, Ohmori, Osamu, Motoki, Takayuki, Shirakawa, Yasuhiro, Yamatsuji, Tomoki, Haisa, Minoru, Matsuoka, Junji, Beer, David G, Nagatsuka, Hitoshi, Tanaka, Noriaki and Naomoto, Yoshio (2008) Dual tyrosine kinase inhibitor for focal adhesion kinase and insulin-like growth factor-I receptor exhibits anticancer effect in esophageal adenocarcinoma in vitro and in vivo. Clinical Cancer Research : an official journal of the American Association for Cancer Research, 14 (14). pp. 4631-4639. ISSN 1078-0432

Wee, Susan, Lengauer, Christoph and Wiederschain, Dmitri (2008) Class IA phosphoinositide 3-kinase isoforms and human tumorigenesis: implications for cancer drug discovery and development. Current Opinion in Oncology, 20 (1). pp. 77-82. ISSN 1040-8746

Wee, Susan, Wiederschain, Dmitri, Maira, Sauveur-Michel, Loo, Alice, Miller, Christine, De Beaumont, Rosalie, Stegmeier, Frank, Yao, Yung-Mae and Lengauer, Christoph (2008) PTEN-deficient cancers depend on PIK3CB. Proceedings of the National Academy of Sciences of the United States of America, 105 (35). pp. 13057-13062. ISSN 0027-8424

Weiss, Andreas, Klein, Corinna, Woodman, Ben, Sathasivam, Kirupa, Bibel, Miriam, Regulier, Etienne, Bates, Gillian and Paganetti, Paolo (2008) Sensitive biochemical aggregate detection reveals aggregation onset before symptom development in cellular and murine models of Huntington's disease. Journal of Neurochemistry, 104 (3). pp. 846-858. ISSN 1471-4159

Weiss, Markus, Fresneau, Marcel, Moenius, Thomas, Stuetz, Anton and Billich, Andreas (2008) Binding of pimecrolimus and tacrolimus to skin and plasma proteins: implications for systemic exposure after topical application. Drug metabolism and disposition: the biological fate of chemicals, 36 (9). pp. 1812-1818. ISSN 1521-009X

Weiss, Markus, Pfaar, Ulrike, Schweitzer, Alain, Wiegand, Hansjörg, Skerjanec, Andrej and Schran, Horst (2008) Biodistribution and plasma protein binding of zoledronic acid. Drug metabolism and disposition: the biological fate of chemicals, 36 (10). pp. 2043-2049. ISSN 1521-009X

Wendorf, Janet, Chesko, James, Kazzaz, Jina, Ugozzoli, Mildred, Vajdy, Michael, O'Hagan, Derek and Singh, Manmohan (2008) A comparison of anionic nanoparticles and microparticles as vaccine delivery systems. Human Vaccines, 4 (1). pp. 44-49. ISSN 1554-8619

Wetzel, S, Renner, S, Nören-Müller, A, Schuffenhauer, Ansgar, Ertl, Peter and Waldmann, Herbert (2008) BIOS: Similarity-based design of natural product derived compound collections. Chemistry Central Journal, 2 (Suppl ). P48. ISSN 1752-153X

Wu, Chunlei, Delano, David, Mitro, Nico, Su, Stephen, Janes, Jeff, Mcclurg, Phillip, Batalov, Sergei, Welch, Genevieve, Zhang, Jie, Orth, Anthony, Walker, John, Glynne, Richard, Cooke, Michael, Takahashi, Joseph, Shimomura, Kazuhiro, Kohsaka, Akira, Bass, Joseph, Saez, Enrique, Wiltshire, Timothy and Su, Andrew (2008) Gene set enrichment in eQTL data identifies novel annotations and pathway regulators. PLoS Genetics, 4 (5). e1000070. ISSN 1553-7404

Yang, Lin, Clarke, Michelle J, Carlson, Brett L, Mladek, Ann C, Schroeder, Mark A, Decker, Paul, Wu, Wenting, Kitange, Gaspar J, Grogan, Patrick T, Goble, Jennie M, Uhm, Joon, Galanis, Evanthia, Giannini, Caterina, Lane, Heidi, James, C David and Sarkaria, Jann N (2008) PTEN loss does not predict for response to RAD001 (Everolimus) in a glioblastoma orthotopic xenograft test panel. Clinical Cancer Research: an official journal of the American Association for Cancer Research, 14 (12). pp. 3993-4001. ISSN 1078-0432

Yang, Lin, Clarke, Michelle J, Carlson, Brett L, Mladek, Ann C, Schroeder, Markus, Decker, Paul, Wu, Wenting, Kitange, Gaspar J, Grogan, Patrick T, Goble, Jennie M, Uhm, Joon, Galanis, Evanthia, Giannini, Caterina, Lane, Heidi, James, David and Sarkaria, Jann N (2008) PTEN loss does not predict for response to RAD001 (Everolimus) in a glioblastoma orthotopic xenograft test panel. Clinical Cancer Research : an official journal of the American Association for Cancer Research, 14 (12). pp. 3993-4001. ISSN 1078-0432

Yang, Yonghua, Rao, Rehka, Shen, Jie, Tang, Yun, Fiskus, Warren, Nechtman, John, Atadja, Peter and Bhalla, Kapil (2008) Role of acetylation and extracellular location of heat shock protein 90alpha in tumor cell invasion. Cancer Research, 68 (12). pp. 4833-4842. ISSN 1538-7445

You, Taek, Lee, Mi, Jenkins, Jeremy, Alzate, Oscar and Dean, Donald (2008) Blocking binding of Bacillus thuringiensis Cry1Aa to Bombyx mori cadherin receptor results in only a minor reduction of toxicity. BMC Biochemistry, 9 (1). p. 3. ISSN 1471-2091

Young, Daniel, Bender, Andreas, Hoyt, Jonathan, McWhinnie, Elizabeth, Chirn, Gung-Wei, Tao, Charles, Tallarico, John, Labow, Mark, Jenkins, Jeremy, Mitchison, Timothy and Feng, Yan (2008) Integrating high-content screening and ligand-target prediction to identify mechanism of action. Nature Chemical Biology, 4 (1). pp. 59-68. ISSN 1552-4469

Yu, Chunrong, Friday, Bret B, Yang, Lin, Atadja, Peter, Wigle, Dennis, Sarkaria, Jann and Adjei, Alex A (2008) Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells. Neuro-Oncology, 10 (3). pp. 309-319. ISSN 1522-8517

Zeggini, Eleftheria, Scott, Laura J, Saxena, Richa, Voight, Benjamin F, Marchini, Jonathan L, Hu, Tianle, de Bakker, Paul I W, Abecasis, Gonçalo R, Almgren, Peter, Andersen, Gitte, Ardlie, Kristin, Boström, Kristina Bengtsson, Bergman, Richard N, Bonnycastle, Lori L, Borch-Johnsen, Knut, Burtt, Noël P, Chen, Hong, Chines, Peter S, Daly, Mark J, Deodhar, Parimal, Ding, Chia-Jen, Doney, Alex S F, Duren, William L, Elliott, Katherine S, Erdos, Michael R, Frayling, Timothy M, Freathy, Rachel M, Gianniny, Lauren, Grallert, Harald, Grarup, Niels, Groves, Christopher J, Guiducci, Candace, Hansen, Torben, Herder, Christian, Hitman, Graham A, Hughes, Thomas, Isomaa, Bo, Jackson, Anne U, Jorgensen, Torben, Kong, Augustine, Kubalanza, Kari, Kuruvilla, Finny G, Kuusisto, Johanna, Langenberg, Claudia, Lango, Hana, Lauritzen, Torsten, Li, Yun, Lindgren, Cecilia M, Lyssenko, Valeriya, Marvelle, Amanda F, Meisinger, Christa, Midthjell, Kristian, Mohlke, Karen L, Morken, Mario A, Morris, Andrew D, Narisu, Narisu, Nilsson, Peter, Owen, Katharine R, Palmer, Colin N A, Payne, Felicity, Perry, John R B, Pettersen, Elin, Platou, Carl, Prokopenko, Inga, Qi, Lu, Qin, Li, Rayner, Nigel W, Rees, Matthew, Roix, Jeffrey, Sandbaek, Anelli, Shields, Beverley, Sjögren, Marketa, Steinthorsdottir, Valgerdur, Stringham, Heather M, Swift, Amy J, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Timpson, Nicholas J, Tuomi, Tiinamaija, Tuomilehto, Jaakko, Walker, Mark, Watanabe, Richard M, Weedon, Michael N, Willer, Cristen J, Illig, Thomas, Hveem, Kristian, Hu, Frank B, Laakso, Markku, Stefansson, Kari, Pedersen, Oluf, Wareham, Nicholas J, Barroso, Inês, Hattersley, Andrew T, Collins, Francis S, Groop, Leif, McCarthy, Mark I, Boehnke, Michael and Altshuler, David (2008) Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nature Genetics, 40 (5). pp. 638-645. ISSN 1546-1718

Zhang, Min, Fu, Wuxia, Prabhu, Sharmila, Moore, James C, Ko, Je, Kim, Jung Woo, Druker, Brian J, Trapp, Valerie, Fruehauf, John, Gram, Hermann, Fan, Hung Y and Ong, S Tiong (2008) Inhibition of polysome assembly enhances imatinib activity against chronic myelogenous leukemia and overcomes imatinib resistance. Molecular and Cellular Biology, 28 (20). pp. 6496-6509. ISSN 1098-5549

Zhou, Liping, Skolnik, Suzanne, Yang, Linhong and Wang, Jianling (2008) Solubility-driven successful drug discovery. Solubility-driven successful drug discovery, Apr/Ma. pp. 20-22.

Zhou, Liping and Wang, Jianling (2008) Physio-chemical Characterization in Drug Discovery. Physio-chemical Characterization in Drug Discovery, 4. pp. 12-18.

Ziermann, Rainer and Sanchez-Guerrero, Sergio Arturo (2008) PROCLEIX West Nile virus assay based on transcription-mediated amplification. Expert Review of Molecular Diagnostics, 8 (3). pp. 239-245. ISSN 1744-8352

le Coutre, Philipp, Ottmann, Oliver G, Giles, Francis, Kim, Dong-Wook, Cortes, Jorge, Gattermann, Norbert, Apperley, Jane F, Larson, Richard A, Abruzzese, Elisabetta, O'Brien, Stephen G, Kuliczkowski, Kazimierz, Hochhaus, Andreas, Mahon, Francois-Xavier, Saglio, Giuseppe, Gobbi, Marco, Kwong, Yok-Lam, Baccarani, Michele, Hughes, Timothy, Martinelli, Giovanni, Radich, Jerald P, Zheng, Ming, Shou, Yaping and Kantarjian, Hagop (2008) Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is active in patients with imatinib-resistant or -intolerant accelerated-phase chronic myelogenous leukemia. Blood, 111 (4). pp. 1834-1839. ISSN 0006-4971

van Meeteren, Laurens A, Brinkmann, Volker, Saulnier-Blache, Jean Sebastien, Lynch, Kevin and Moolenaar, Wouter H (2008) Anticancer activity of FTY720: phosphorylated FTY720 inhibits autotaxin, a metastasis-enhancing and angiogenic lysophospholipase D. Cancer Letters, 266 (2). pp. 203-208. ISSN 0304-3835

Book Section

Evans, Tom (2008) Mucosal Vaccination Against HIV-1. In: Immunity Against Mucosal Pathogens. Springer Netherlands, Netherlands, pp. 483-495. ISBN 9781402084119

This list was generated on Tue Nov 5 04:33:40 2024 UTC.

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