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Number of items: 382.

A

Abdulla, Salim and Sagara, Issaka and Borrmann, Steffen and D'Alessandro, Umberto and González, Raquel and Hamel, Mary and Ogutu, Bernhards and Mårtensson, Andreas and Lyimo, John and Maiga, Hamma and Sasi, Philip and Nahum, Alain and Bassat, Quique and Juma, Elizabeth and Otieno, Lucas and Björkman, Anders and Beck, Hans Peter and Andriano, Kim and Cousin, Marc and Lefevre, Gilbert and Ubben, David and Premji, Zulfikarali (2008) Efficacy and safety of artemether-lumefantrine dispersible tablets compared with crushed commercial tablets in African infants and children with uncomplicated malaria: a randomised, single-blind, multicentre trial. Lancet, 372 (9652). pp. 1819-1827. ISSN 1474-547X

Abramowski, Dorothee and Wiederhold, Karl-Heinz and Furrer, Ulrich and Jaton, Anne-Lise and Neuenschwander, Anton and Runser, Marie-Josephine and Danner, Simone and Reichwald, Julia and Ammaturo, Domenico and Staab, Dieter and Stoeckli, Markus and Rueeger, Heinrich and Neumann, Ulf and Staufenbiel, Matthias (2008) Dynamics of Abeta turnover and deposition in different beta-amyloid precursor protein transgenic mouse models following gamma-secretase inhibition. The Journal of Pharmacology and Experimental Therapeutics, 327 (2). pp. 411-424. ISSN 1521-0103

Abudalu, Mohammed and Tyring, Stephen and Koltun, William and Bodsworth, Neil and Hamed, Kamal (2008) Single-day, patient-initiated famciclovir therapy versus 3-day valacyclovir regimen for recurrent genital herpes: a randomized, double-blind, comparative trial. Clinical Infectious Diseases : an official publication of the Infectious Diseases Society of America, 47 (5). pp. 651-658. ISSN 1537-6591

Almeida, M. Q. and Fragoso, M. C. B. V. and Lotfi, C. F. P. and Santos, M. G. and Nishi, M. Y. and Costa, M. H. S. and Lerario, A. M. and Maciel, C. C. and Mattos, G. E. and Jorge, A. A. L. and Mendonca, B. B. and Latronico, A. C. (2008) Expression of Insulin-Like Growth Factor-II and Its Receptor in Pediatric and Adult Adrenocortical Tumors. Journal of Clinical Endocrinology & Metabolism, 93 (9). pp. 3524-3531. ISSN 0021-972X

Alten, Rieke and Gram, Hermann and Joosten, Leo A and van den Berg, Wim B and Sieper, Joachim and Wassenberg, Siegfrid and Burmester, Gerd and van Riel, Piet and Diaz-Lorente, Maria and Bruin, Gerardus and Woodworth, Thasia G. and Rordorf, Christiane and Batard, Yannick and Wright, Andrew and Jung, Thomas (2008) The human anti-IL-1 beta monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis. Arthritis research & therapy, 10 (3). R67. ISSN 1478-6362

Alten, Rieke and Gram, Hermann and Joosten, Leo and Berg, Wim and Sieper, Joachim and Wassenberg, Siegfrid and Burmester, Gerd and van Riel, Piet and Diaz-Lorente, Maria and Bruin, Gerardus and Woodworth, Thasia G. and Rordorf, Christiane and Batard, Yannick and Wright, Andrew and Jung, Thomas (2008) The human anti-IL-1ß monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis. Arthritis Research & Therapy, 10 (3). R67. ISSN 1478-6354

Alvarez, Carlos (2008) On the origins of arrestin and rhodopsin. BMC Evolutionary Biology, 8 (1). p. 222. ISSN 1471-2148

Andreae, Marc and Steiner, Thomas and Hueber, Matthieu and Schopfer, Ulrich and Smith, Robert and Igo, Debra and Cantrell, Daryl and Hohos, Aaron and Kiwanuka, Andrew (2008) Closing the gap between centralized and decentralized compound management approaches. Combinatorial Chemistry & High Throughput Screening, 11 (10). pp. 825-833. ISSN 1386-2073

Atadja, Peter and Shao, Wenlin and Wang, Y and Growney, Joseph and Feng, Y and Yao, Yao and Wallace, A and Crisanti, C and Fawell, Stephen and Albelda, S (2008) Efficacy of panobinostat (LBH589) in lung cancer: potent anticancer activity in both in vitro and in vivo tumor models. European Journal of Cancer Supplements, 6 (12). pp. 48-49.

Ayalasomayajula, Surya and Tchaloyan, Stephanie and Yeh, Ching-Ming and Bizot, Marie-Noelle and Dieterich, Hans Armin and Howard, Danny and Dole, William (2008) A study of the pharmacokinetic interactions of the direct renin inhibitor aliskiren with allopurinol, celecoxib and cimetidine in healthy subjects. Current Medical Research and Opinion, 24 (3). pp. 717-726. ISSN 1473-4877

Ayalasomayajula, Surya and Yeh, Ching-Ming and Vaidyanathan, Sujata and Flannery, Brian and Dieterich, Hans Armin and Howard, Danny and Bedigian, Martin and Dole, William (2008) Effects of aliskiren, a direct Renin inhibitor, on cardiac repolarization and conduction in healthy subjects. Journal of Clinical Pharmacology, 48 (7). pp. 799-811. ISSN 0091-2700

B

Bagnoli, Fabio and Moschioni, Monica and Donati, Claudio and Dimitrovska, Valentina and Ferlenghi, Ilaria and Facciotti, Claudia and Muzzi, Alessandro and Giusti, Fabiola and Emolo, Carla and Sinisi, Antonella and Hilleringmann, Markus and Pansegrau, Werner and Censini, Stefano and Rappuoli, Rino and Covacci, Antonello and Masignani, Vega and Barocchi, Michele A (2008) A second pilus type in Streptococcus pneumoniae is prevalent in emerging serotypes and mediates adhesion to host cells. Journal of Bacteriology, 190 (15). pp. 5480-5492. ISSN 1098-5530

Bardotti, Angela and Averani, Giovanni and Berti, Francesco and Berti, Stefania and Carinci, Valeria and D'Ascenzi, Sandro and Fabbri, Barbara and Giannini, Sara and Giannozzi, Aldo and Magagnoli, Claudia and Proietti, Daniela and Norelli, Francesco and Rappuoli, Rino and Ricci, Stefano and Costantino, Paolo (2008) Physicochemical characterisation of glycoconjugate vaccines for prevention of meningococcal diseases. Vaccine, 26 (18). pp. 2284-2296. ISSN 0264-410X

Barlaskar, F. M. and Spalding, A. C. and Heaton, J. H. and Kuick, R. and Kim, A. C. and Thomas, D. G. and Giordano, T. J. and Ben-Josef, E. and Hammer, G. D. (2008) Preclinical Targeting of the Type I Insulin-Like Growth Factor Receptor in Adrenocortical Carcinoma. Journal of Clinical Endocrinology & Metabolism, 94 (1). pp. 204-212. ISSN 0021-972X

Bartholomaus, I and Schlager, C and Brinkmann, Volker and Wekerle, H and Flugel, A (2008) Intravital 2-photon imaging of encephalitogenic effector cells during fingolimod (FTY720) treatment of experimental autoimmune encephalomyelitis. Multiple Sclerosis, 14 (No 1 Supplement). S30-S31.

Beaud, Marie-Laure and Schmidlin, Eric and Wannier, Thierry and Freund, Patrick and Bloch, Jocelyne and Mir, Anis and Schwab, Martin E and Rouiller, Eric M (2008) Anti-Nogo-A antibody treatment does not prevent cell body shrinkage in the motor cortex in adult monkeys subjected to unilateral cervical cord lesion. BMC neuroscience, 9 (5). ISSN 1471-2202

Beierle, Elizabeth A and Trujillo, Angelica and Nagaram, Abhilasha and Golubovskaya, Vita M and Cance, William G and Kurenova, Elena V (2008) TAE226 inhibits human neuroblastoma cell survival. Cancer Investigation, 26 (2). pp. 145-151. ISSN 1532-4192

Bell, Leslie and Bickford, Shari and Nguyen, Phong and Wang, Jianling and He, Timothy and Zhang, Bailin and Friche, Yannick and Zimmerlin, Alfred Gilbert and Urban, Laszlo and Bojanic, Dejan (2008) Evaluation of fluorescence- and mass spectrometry-based CYP inhibition assays for use in drug discovery. Journal of Biomolecular Screening : the official journal of the Society for Biomolecular Screening, 13 (5). pp. 343-353. ISSN 1087-0571

Bender, Andreas and Bojanic, Dejan and Davies, John and Crisman, Thomas and Mikhailov, Dmitri and Scheiber, Josef and Jenkins, Jeremy and Deng, Zhan and Hill, William and Popov, Maxim and Jacoby, Edgar and Glick, Meir (2008) Which aspects of HTS are empirically correlated with downstream success? Current Opinion in Drug Discovery & Development, 11 (3). pp. 327-337. ISSN 1367-6733

Berglund, Ken and Schleich, Wolfram and Wang, Hong and Feng, Guoping and Hall, William C and Kuner, Thomas and Augustine, George J (2008) Imaging synaptic inhibition throughout the brain via genetically targeted Clomeleon. Brain Cell Biology, 36 (1-4). pp. 101-118. ISSN 1559-7113

Bergstroem, Mats and Monazzam, Azita and Razifar, Pasha and Ide, Susan and Josephsson, Raymond and Langstrom, Bengt (2008) Modeling spheroid growth, PET tracer uptake, and treatment effects of the Hsp90 inhibitor NVP-AUY922. Journal of Nuclear Medicine: official publication, Society of Nuclear Medicine, 49 (7). pp. 1204-1210. ISSN 0161-5505

Bingel-Erlenmeyer, Rouven and Kohler, Rebecca and Kramer, Guenter and Sandikci, Arzu and Antolic, Snjezana and Maier, Timm and Schaffitzel, Christiane and Wiedmann, Brigitte and Bukau, Bernd and Ban, Nenad (2008) A peptide deformylase-ribosome complex reveals mechanism of nascent chain processing. Nature, 452 (7183). pp. 108-111. ISSN 1476-4687

Bingel-Erlenmeyer, Rouven and Kohler, Rebecca and Kramer, Günter and Sandikci, Arzu and Antolić, Snjezana and Maier, Timm and Schaffitzel, Christiane and Wiedmann, Brigitte and Bukau, Bernd and Ban, Nenad (2008) A peptide deformylase-ribosome complex reveals mechanism of nascent chain processing. Nature, 452 (7183). pp. 108-111. ISSN 1476-4687

Biron, Eric and Chatterjee, Jayanta and Ovadia, Oded and Langenegger, Daniel and Brueggen, Josef and Hoyer, Daniel and Schmid, Herbert and Jelinek, Raz and Gilon, Chaim and Hoffman, Amnon and Kessler, Horst (2008) Improving oral bioavailability of peptides by multiple N-methylation: somatostatin analogues. Angewandte Chemie (International ed. in English), 47 (14). pp. 2595-2599. ISSN 1521-3773

Bissiere, Stephanie and Plachta, Nicolas and Hoyer, Daniel and Mcallister, Kevin and Olpe, Hans-Rudolf and Grace, Anthony and Cryan, John F. (2008) The rostral anterior cingulate cortex modulates the efficiency of amygdala-dependent fear learning. Biological Psychiatry, 63 (9). pp. 821-831. ISSN 1873-2402

Blancafort, Pilar and Tschan, Mario P and Bergquist, Sharon and Guthy, Daniel Alexander and Brachat, Arndt Holger and Sheeter, Dennis A and Torbett, Bruce E and Erdmann, Dirk and Barbas, Carlos F (2008) Modulation of drug resistance by artificial transcription factors. Molecular Cancer Therapeutics, 7 (3). pp. 688-697. ISSN 1535-7163

Blanchard Rohner, Geraldine and Snape, Matthew D and Kelly, Dominic F and John, Tessa and Morant, Anita and Yu, Ly-Mee and Borkowski, Astrid and Ceddia, Francesca and Borrow, Ray and Siegrist, Claire-Anne and Pollard, Andrew J (2008) The magnitude of the antibody and memory B cell responses during priming with a protein-polysaccharide conjugate vaccine in human infants is associated with the persistence of antibody and the intensity of booster response. Journal of Immunology (Baltimore, Md. : 1950), 180 (4). pp. 2165-2173. ISSN 0022-1767

Blanchard Rohner, Geraldine and Snape, Matthew D and Kelly, Dominic F and John, Tessa and Morant, Anita and Yu, Ly-Mee and Borkowski, Astrid and Ceddia, Francesca and Borrow, Ray and Siegrist, Claire-Anne and Pollard, Andrew J (2008) The magnitude of the antibody and memory B cell responses during priming with a protein-polysaccharide conjugate vaccine in human infants is associated with the persistence of antibody and the intensity of booster response. The Journal of immunology : official journal of the American Association of Immunologists, 180 (4). pp. 2165-2173. ISSN 0022-1767

Ble, Francois-Xavier and Cannet, Catherine and Zurbruegg, Stefan and Karmouty Quintana, Harry and Bergmann, Reinhard and Frossard, Nelly and Trifilieff, Alexandre and Beckmann, Nicolau (2008) Allergen-induced lung inflammation in actively sensitized mice assessed with MR imaging. Radiology, 248 (3). pp. 834-843. ISSN 1527-1315

Boath, Alistair and Graf, Christine and Lidome, Emilie and Ullrich, Thomas and Nussbaumer, Peter and Bornancin, Frederic (2008) Regulation and traffic of ceramide 1-phosphate produced by ceramide kinase: comparative analysis to glucosylceramide and sphingomyelin. The Journal of Biological Chemistry, 283 (13). pp. 8517-8526. ISSN 0021-9258

Boath, Alistair and Graf, Christine and Lidome, Emilie and Ullrich, Thomas and Nussbaumer, Peter and Bornancin, Frederic (2008) Regulation and traffic of ceramide 1-phosphate produced by ceramide kinase: comparative analysis to glucosylceramide and sphingomyelin. The Journal of Biological Chemistry, 283 (13). pp. 8517-8526. ISSN 0021-9258

Boehme, J and Suttorp, M and Fischer, R and Bornhaeuser, M and Gasser, Juerg Andreas (2008) Influence of Imatinib on Bone Remodeling in Juvenile Mice. Journal of Bone and Mineral Research, 23. S189.

Bowen, David G and Shoukry, Naglaa H and Grakoui, Arash and Fuller, Michael J and Cawthon, Andrew G and Dong, Christine and Hasselschwert, Dana L and Brasky, Kathleen M and Freeman, Gordon J and Seth, Nilufer P and Wucherpfennig, Kai W and Houghton, Mortimer and Walker, Christopher M (2008) Variable patterns of programmed death-1 expression on fully functional memory T cells after spontaneous resolution of hepatitis C virus infection. Journal of virology, 82 (10). pp. 5109-5114. ISSN 1098-5514

Breitling, Rainer and Li, Yang and Tesson, Bruno M and Fu, Jingyuan and Wu, Chunlei and Wiltshire, Tim and Gerrits, Alice and Bystrykh, Leonid V and de Haan, Gerald and Su, Andrew and Jansen, Ritsert C (2008) Genetical genomics: spotlight on QTL hotspots. PLoS Genetics, 4 (10). e1000232. ISSN 1553-7404

Broeker, Michael and Kollaritsch, Herwig (2008) After a tick bite in a tick-borne encephalitis virus endemic area: current positions about post-exposure treatment. Vaccine, 26 (7). pp. 863-868. ISSN 0264-410X

Broeker, Michael and Kollaritsch, Herwig (2008) After a tick bite in a tick-borne encephalitis virus endemic area: current positions about post-exposure treatment. Vaccine, 26 (7). pp. 863-868. ISSN 0264-410X

Brouwers, J E M and Lambers, F M and Gasser, Juerg Andreas and van Rietbergen, B and Huiskes, R (2008) Bone degeneration and recovery after early and late bisphosphonate treatment of ovariectomized wistar rats assessed by in vivo micro-computed tomography. Calcified Tissue International, 82 (3). pp. 202-211. ISSN 0171-967X

Brouwers, J E M and Lambers, F M and Gasser, Juerg Andreas and van Rietbergen, B and Huiskes, R (2008) Bone degeneration and recovery after early and late bisphosphonate treatment of ovariectomized wistar rats assessed by in vivo micro-computed tomography. Calcified tissue international, 82 (3). pp. 202-211. ISSN 0171-967X

Bruin, Gerardus and Faller, Thomas and Wiegand, Hansjoerg and Schweitzer, Alain and Nick, Hanspeter and Schneider, Josef and Boernsen, K. Olaf and Waldmeier, Felix (2008) Pharmacokinetics, distribution, metabolism, and excretion of deferasirox and its iron complex in rats. Drug metabolism and disposition: the biological fate of chemicals, 36 (12). pp. 2523-2538. ISSN 1521-009X

Bruin, Gerardus and Faller, Thomas and Wiegand, Hansjoerg and Schweitzer, Alain and Nick, Hanspeter and Schneider, Josef and Boernsen, K. Olaf and Waldmeier, Felix (2008) Pharmacokinetics, distribution, metabolism, and excretion of deferasirox and its iron complex in rats. Drug metabolism and disposition: the biological fate of chemicals, 36 (12). pp. 2523-2538. ISSN 1521-009X

Bruin, Gerardus and Faller, Thomas and Wiegand, Hansjoerg and Schweitzer, Alain and Nick, Hanspeter and Schneider, Josef and Boernsen, K. Olaf and Waldmeier, Felix (2008) Pharmacokinetics, Distribution, Metabolism, and Excretion of Deferasirox and its Iron Complex in Rats. Drug Metabolism and Disposition, 36 (12). pp. 2523-2538. ISSN 1521-009X

Buechau, Amanda S and Schauber, Jürgen and Hultsch, Thomas and Stuetz, Anton and Gallo, Richard L (2008) Pimecrolimus enhances TLR2/6-induced expression of antimicrobial peptides in keratinocytes. The Journal of Investigative Dermatology, 128 (11). pp. 2646-2654. ISSN 1523-1747

C

CHANKVETADZE, Bezhan and Francotte, Eric (2008) Preface: Enantioseparations - Dedicated to Wolfgang Lindner. Journal of Chromatography B, 875 (1). p. 1. ISSN 15700232

Calvo, Jennifer and Daniels, Thomas and Wang, Xiaomei and Paul, Angelika and Lin, Jiandie and Spiegelman, Bruce M and Stevenson, Susan and Rangwala, Shamina (2008) Muscle-specific expression of PPARgamma coactivator-1alpha improves exercise performance and increases peak oxygen uptake. Journal of Applied Physiology (Bethesda, Md. : 1985), 104 (5). pp. 1304-1312. ISSN 8750-7587

Campa, Cristiana and Baiutti, Edi and Flamigni, Anna (2008) Capillary electrophoresis of sugar acids. Methods in Molecular Biology (Clifton, N.J.), 384. pp. 307-355. ISSN 1064-3745

Cao, Weihuan and Song, Ho-Juhn and Gangi, Tina and Kelkar, Anju and Antani, Isha and Garza, Dan and Konsolaki, Mary (2008) Identification of novel genes that modify phenotypes induced by Alzheimer's beta-amyloid overexpression in Drosophila. Genetics, 178 (3). pp. 1457-1471. ISSN 0016-6731

Caputo, Antonella and Brocca-Cofano, Egidio and Castaldello, Arianna and Voltan, Rebecca and Gavioli, Riccardo and Srivastava, Indresh K and Barnett, Susan W and Cafaro, Aurelio and Ensoli, Barbara (2008) Characterization of immune responses elicited in mice by intranasal co-immunization with HIV-1 Tat, gp140 DeltaV2Env and/or SIV Gag proteins and the nontoxicogenic heat-labile Escherichia coli enterotoxin. Vaccine, 26 (9). pp. 1214-1227. ISSN 0264-410X

Caputo, Antonella and Brocca-Cofano, Egidio and Castaldello, Arianna and Voltan, Rebecca and Gavioli, Riccardo and Srivastava, Indresh K and Barnett, Susan W and Cafaro, Aurelio and Ensoli, Barbara (2008) Characterization of immune responses elicited in mice by intranasal co-immunization with HIV-1 Tat, gp140 DeltaV2Env and/or SIV Gag proteins and the nontoxicogenic heat-labile Escherichia coli enterotoxin. Vaccine, 26 (9). pp. 1214-1227. ISSN 0264-410X

Caputo, Antonella and Brocca-Cofano, Egidio and Castaldello, Arianna and Voltan, Rebecca and Gavioli, Riccardo and Srivastava, Indresh K and Barnett, Susan W and Cafaro, Aurelio and Ensoli, Barbara (2008) Characterization of immune responses elicited in mice by intranasal co-immunization with HIV-1 Tat, gp140 DeltaV2Env and/or SIV Gag proteins and the nontoxicogenic heat-labile Escherichia coli enterotoxin. Vaccine, 26 (9). pp. 1214-1227. ISSN 0264-410X

Chen, Jian and Shi, Xiaoying and Padmanabhan, Ranjani and Wang, Qiong and Wu, Zhidan and Stevenson, Susan and Hild, Marc and Garza, Dan and Li, Hao (2008) Identification of novel modulators of mitochondrial function by a genome-wide RNAi screen in Drosophila melanogaster. Genome Research, 18 (1). pp. 123-136. ISSN 1088-9051

Chen, Yuefeng and Wei, Tao and Yan, Lei and Lawrence, Frank and Qian, Hui-Rong and Burkholder, Timothy P and Starling, James J and Yingling, Jonathan M and Shou, Jianyong (2008) Developing and applying a gene functional association network for anti-angiogenic kinase inhibitor activity assessment in an angiogenesis co-culture model. BMC Genomics, 9. p. 264. ISSN 1471-2164

Chene, Patrick (2008) Challenges in design of biochemical assays for the identification of small molecules to target multiple conformations of protein kinases. Drug Discovery Today, 13 (11-12). pp. 522-529. ISSN 1359-6446

Chene, Patrick (2008) Challenges in design of biochemical assays for the identification of small molecules to target multiple conformations of protein kinases. Drug Discovery Today, 13 (11-12). pp. 522-529. ISSN 1359-6446

Chene, Patrick (2008) PcrA/UvrD/Rep DNA helicases in bacterial genomes. Biochemical Systematics and Ecology, 36 (2). pp. 101-109. ISSN 0305-1978

Chesko, James and Kazzaz, Jina and Ugozzoli, Mildred and Singh, Manmohan and O'Hagan, Derek T and Madden, Claire and Perkins, Mark and Patel, Nikin (2008) Characterization of antigens adsorbed to anionic PLG microparticles by XPS and TOF-SIMS. Journal of Pharmaceutical Sciences, 97 (4). pp. 1443-1453. ISSN 0022-3549

Chiba, Hatsune and Hirasawa, Ryutaro and Kaneda, Masahiro and Amakawa, Yuko and Li, En and Sado, Takashi and Sasaki, Hiroyuki (2008) De novo DNA methylation independent establishment of maternal imprint on X chromosome in mouse oocytes. Genesis (New York, N.Y. : 2000), 46 (12). pp. 768-774. ISSN 1526-968X

Chung, Yuen-Li and Troy, Helen and Kristeleit, Rebecca and Aherne, Wynne and Jackson, L Elizabeth and Atadja, Peter and Griffiths, John R and Judson, Ian R and Workman, Paul and Leach, Martin O and Beloueche-Babari, Mounia (2008) Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of a novel histone deacetylase inhibitor, LAQ824, in human colon carcinoma cells and xenografts. Neoplasia (New York, N.Y.), 10 (4). pp. 303-313. ISSN 1476-5586

Coers, Jörn and Bernstein-Hanley, Isaac and Grotsky, David and Parvanova, Iana and Howard, Jonathan C and Taylor, Gregory A and Dietrich, William and Starnbach, Michael N (2008) Chlamydia muridarum evades growth restriction by the IFN-gamma-inducible host resistance factor Irgb10. Journal of Immunology (Baltimore, Md. : 1950), 180 (9). pp. 6237-6245. ISSN 0022-1767

Cooper, P J and Ayre, Gareth and Martin, Carmen and Rizzo, J A and Ponte, E V and Cruz, A A (2008) Geohelminth infections: a review of the role of IgE and assessment of potential risks of anti-IgE treatment. Allergy, 63 (4). pp. 409-417. ISSN 1398-9995

Cooper, P J and Ayre, Gareth and Martin, Carmen and Rizzo, J A and Ponte, E V and Cruz, A A (2008) Geohelminth infections: a review of the role of IgE and assessment of potential risks of anti-IgE treatment. Allergy, 63 (4). pp. 409-417. ISSN 1398-9995

Coote, Kevin and Atherton, Hazel and Young, Alice and Sugar, Rosemary and Burrows, Rachel and Smith, Nicola and Schlaeppi, Jean-Marc and Groot-Kormelink, Paul and Gosling, Martin and Danahay, Henry (2008) The guinea-pig tracheal potential difference as an in vivo model for the study of epithelial sodium channel function in the airways. British Journal of Pharmacology, 155 (7). pp. 1025-1033. ISSN 1476-5381

Crisman, Thomas and Bender, Andreas and Milik, Mariusz and Jenkins, Jeremy and Scheiber, Josef and Sukuru, Sai Chetan and Fejzo, Jasna and Hommel, Ulrich and Davies, John and Glick, Meir (2008) "Virtual fragment linking": an approach to identify potent binders from low affinity fragment hits. Journal of Medicinal Chemistry, 51 (8). pp. 2481-2491. ISSN 0022-2623

Crooks, Emma T and Jiang, Pengfei and Franti, Michael and Wong, Sharon and Zwick, Michael B and Hoxie, James A and Robinson, James E and Moore, Penny L and Binley, James M (2008) Relationship of HIV-1 and SIV envelope glycoprotein trimer occupation and neutralization. Virology, 377 (2). pp. 364-378. ISSN 0042-6822

Cross, N C P and Daley, G Q and Green, A R and Hughes, T P and Jamieson, C and Manley, Paul W. and Mughal, T and Perrotti, D and Radich, J and Skoda, R and Soverini, S and Vainchenker, W and Verstovsek, S and Villeval, J-L and Goldman, J M (2008) BCR-ABL1-positive CML and BCR-ABL1-negative chronic myeloproliferative disorders: some common and contrasting features. Leukemia : Official Journal of the Leukemia Society of America, Leukemia Research Fund, U.K, 22 (11). pp. 1975-1989. ISSN 1476-5551

Croyle, Michelle and Akeno, Nagako and Knauf, Jeffrey A and Fabbro, Doriano and Chen, Xu and Baumgartner, Jacqueline E and Lane, Heidi and Fagin, James A (2008) RET/PTC-induced cell growth is mediated in part by epidermal growth factor receptor (EGFR) activation: evidence for molecular and functional interactions between RET and EGFR. Cancer Research, 68 (11). pp. 4183-4191. ISSN 1538-7445

Cunningham, Matthew and Thomas, Hilary and Christopher, Marks and Margaret, Green and Zhen, Fan and Helmout, Modjtahedi (2008) Co-targeting the EGFR and IGF-IR with anti-EGFR monoclonal antibody ICR62 and the IGF-IR tyrosine kinase inhibitor NVP-AEW541 in colorectal cancer cells. International Journal of Oncology, 33 (5). pp. 1107-1113. ISSN 1019-6439

D

D'Eon, Tara and Pierce, Kerry and Roix, Jeffrey and Tyler, Andrew and Chen, Hong and Teixeira, Sandra (2008) The role of adipocyte insulin resistance in the pathogenesis of obesity-related elevations in endocannabinoids. Diabetes, 57 (5). pp. 1262-1268. ISSN 1939-327X

De Bruyne, Elke and Bos, Tomas Jan and Asosingh, Kewal and Vande Broek, Isabelle and Menu, Eline and Van Valckenborgh, Els and Atadja, Peter and Coiteux, Valérie and Leleu, Xavier and Thielemans, Kris and Van Camp, Ben and Vanderkerken, Karin and Van Riet, Ivan (2008) Epigenetic silencing of the tetraspanin CD9 during disease progression in multiple myeloma cells and correlation with survival. Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 14 (10). pp. 2918-2926. ISSN 1078-0432

Del Vecchio, Mariangela and Balducci, Enrico (2008) Mono ADP-ribosylation inhibitors prevent inflammatory cytokine release in alveolar epithelial cells. Molecular and Cellular Biochemistry, 310 (1-2). pp. 77-83. ISSN 0300-8177

Del Vecchio, Mariangela and Balducci, Enrico (2008) Mono ADP-ribosylation inhibitors prevent inflammatory cytokine release in alveolar epithelial cells. Molecular and Cellular Biochemistry, 310 (1-2). pp. 77-83. ISSN 0300-8177

Demuth, Andreas and Aharonowitz, Yair and Bachmann, Till T and Blum-Oehler, Gabriele and Buchrieser, Carmen and Covacci, Antonello and Dobrindt, Ulrich and Emody, Levente and van der Ende, Arie and Ewbank, Jonathan and Fernandez, Luis Angel and Frosch, Matthias and Garcia-Del Portillo, Francisco and Gilmore, Michael S and Glaser, Philippe and Goebel, Werner and Hasnain, Seyed E and Heesemann, Juergen and Islam, Khalid and Korhonen, Timo and Maiden, Martin and Meyer, Thomas F and Montecucco, Cesare and Oswald, Eric and Parkhill, Julian and Pucciarelli, M Graciela and Ron, Eliora and Svanborg, Catharina and Uhlin, Bernt Eric and Wai, Sun Nyunt and Wehland, Juergen and Hacker, Joerg (2008) Pathogenomics: an updated European Research Agenda. Infection, Genetics and Evolution : Journal of Molecular Epidemiology and evolutionary genetics in infectious diseases, 8 (3). pp. 386-393. ISSN 1567-1348

Dodeller, Francis and Gottar-Guillier, Marie and Huesken, Dieter and Iourgenko, Vadim and Cenni, Bruno (2008) The lysosomal transmembrane protein 9B regulates the activity of inflammatory signaling pathways. The Journal of Biological Chemistry, 283 (31). pp. 21487-21494. ISSN 0021-9258

Ducray, Pierre and Gauvry, Noelle and Pautrat, Francois and Goebel, Thomas and Fruechtel, Joerg and Desaules, Yves and Schorderet Weber, Sandra and Bouvier, Jacques and Wagner, Beatrix and Froelich, Olivier and Kaminsky, Ronald (2008) Discovery of amino-acetonitrile derivatives, a new class of synthetic anthelmintic compounds. Bioorganic & Medicinal Chemistry Letters, 18 (9). pp. 2935-2938. ISSN 1464-3405

Dultz, Elisa and Hildenbeutel, Markus and Martoglio, Bruno and Hochman, Jacob and Dobberstein, Bernhard and Kapp, Katja (2008) The signal peptide of the mouse mammary tumor virus Rem protein is released from the endoplasmic reticulum membrane and accumulates in nucleoli. The Journal of Biological Chemistry, 283 (15). pp. 9966-9976. ISSN 0021-9258

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Dutt, Amit and Salvesen, Helga B and Chen, Tzu-Hsiu and Ramos, Alex H and Onofrio, Robert C and Hatton, Charlie and Nicoletti, Richard and Winckler, Wendy and Grewal, Rupinder and Hanna, Megan and Wyhs, Nicolas and Ziaugra, Liuda and Richter, Daniel J and Trovik, Jone and Engelsen, Ingeborg B and Stefansson, Ingunn M and Fennell, Tim and Cibulskis, Kristian and Zody, Michael C and Akslen, Lars A and Gabriel, Stacey and Wong, Kwok-Kin and Sellers, William and Meyerson, Matthew and Greulich, Heidi (2008) Drug-sensitive FGFR2 mutations in endometrial carcinoma. Proceedings of the National Academy of Sciences of the United States of America, 105 (25). pp. 8713-8717. ISSN 1091-6490

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Elis, Winfried and Triantafellow, Ellen and Wolters, Natalie M and Sian, Katie R and Caponigro, Giordano and Borawski, Jason and Gaither, Larry and Murphy, Leo and Finan, Peter and Mackeigan, Jeff (2008) Down-regulation of class II phosphoinositide 3-kinase alpha expression below a critical threshold induces apoptotic cell death. Molecular Cancer Research : MCR, 6 (4). pp. 614-623. ISSN 1541-7786

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Galanello, Renzo and Piga, Antonio and Cappellini, Maria Domenica and Forni, Monique and Zappu, Antonella and Origa, Raffaella and Dutreix, Catherine and Belleli, Rossella and Ford, John Malcolm and Riviere, Gilles-Jacques and Balez, Sebastien and Alberti, Daniele Maria and Sechaud, Romain (2008) Effect of food, type of food, and time of food intake on deferasirox bioavailability: recommendations for an optimal deferasirox administration regimen. Journal of clinical pharmacology, 48 (4). pp. 428-435. ISSN 0091-2700

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Gengenbacher, Martin and Xu, Ting and Niyomrattanakit, Pornwaratt and Spraggon, Glen and Dick, Thomas (2008) Biochemical and structural characterization of the putative dihydropteroate synthase ortholog Rv1207 of Mycobacterium tuberculosis. FEMS Microbiology Letters, 287 (1). pp. 128-135. ISSN 0378-1097

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Giannoni, Francesca and Shea, Ashley and Inglis, Chandra and Lee, Lian Ni and Sarawar, Sally R (2008) CD40 engagement on dendritic cells, but not on B or T cells, is required for long-term control of murine gammaherpesvirus 68. Journal of Virology, 82 (22). pp. 11016-11022. ISSN 1098-5514

Gillet, Ludovic and Namoto, Kenji and Ruchti, Alexandra and Hoving, Sjouke and Boesch, Danielle and Inverardi, Bruno and Mueller, Dieter and Coulot, Michele and Schindler, Patrick and Schweigler, Patrick and Bernardi, Anna and Gil Parrado, Shirley (2008) In-cell selectivity profiling of serine protease inhibitors by activity-based proteomics. Molecular & Cellular Proteomics : MCP, 7 (7). pp. 1241-1253. ISSN 1535-9484

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Gjoni, Tina and Urwyler, Stephan (2008) Receptor activation involving positive allosteric modulation, unlike full agonism, does not result in GABAB receptor desensitization. Neuropharmacology, 55 (8). pp. 1293-1299. ISSN 0028-3908

Glickman, Fraser and Schmid, Andres and Ferrand, Sandrine (2008) Scintillation proximity assays in high-throughput screening. Assay and Drug Development Technologies, 6 (3). pp. 433-455. ISSN 1540-658X

Goddyn, Hannelore and Callaerts-Vegh, Zsuzsanna and Stroobants, Stijn and Dirikx, Trinette and Vansteenwegen, Debora and Hermans, Dirk and Van Der Putten, P. Herman and D'Hooge, Rudi (2008) Deficits in acquisition and extinction of conditioned responses in mGluR7 knockout mice. Neurobiology of Learning and Memory, 90 (1). pp. 103-111. ISSN 1095-9564

Golks, Alexander and Guerini, Danilo (2008) The O-linked N-acetylglucosamine modification in cellular signalling and the immune system. 'Protein modifications: beyond the usual suspects' review series. EMBO Reports, 9 (8). pp. 748-753. ISSN 1469-3178

Golubovskaya, Vita M and Nyberg, Carl and Zheng, Min and Kweh, Frederick and Magis, Andrew and Ostrov, David and Cance, William G (2008) A small molecule inhibitor, 1,2,4,5-benzenetetraamine tetrahydrochloride, targeting the y397 site of focal adhesion kinase decreases tumor growth. Journal of Medicinal Chemistry, 51 (23). pp. 7405-7416. ISSN 1520-4804

Golubovskaya, Vita M and Virnig, Christopher and Cance, William G (2008) TAE226-induced apoptosis in breast cancer cells with overexpressed Src or EGFR. Molecular Carcinogenesis, 47 (3). pp. 222-234. ISSN 1098-2744

Goodship, Allen and Blunn, Gordon W and Green, Jonathan and Coathup, Melanie J (2008) Prevention of strain-related osteopenia in aseptic loosening of hip prostheses using perioperative bisphosphonate. Journal of Orthopaedic Research : official publication of the Orthopaedic Research Society, 26 (5). pp. 693-703. ISSN 1554-527X

Gopalsamy, Ariamala and Shi, Mengxiao and Golas, Jennifer and Vogan, Erik and Jacob, Jaison and Johnson, Mark and Lee, Frederick and Nilakantan, Ramaswamy and Petersen, Roseann and Svenson, Kristin and Chopra, Rajiv and Tam, May S and Wen, Yingxia and Ellingboe, John and Arndt, Kim and Boschelli, Frank (2008) Discovery of benzisoxazoles as potent inhibitors of chaperone heat shock protein 90. Journal of Medicinal Chemistry, 51 (3). pp. 373-375. ISSN 0022-2623

Gopalsamy, Ariamala and Shi, Mengxiao and Golas, Jennifer and Vogan, Erik and Jacob, Jaison and Johnson, Mark and Lee, Frederick and Nilakantan, Ramaswamy and Petersen, Roseann and Svenson, Kristin and Chopra, Rajiv and Tam, May S and Wen, Yingxia and Ellingboe, John and Arndt, Kim and Boschelli, Frank (2008) Discovery of benzisoxazoles as potent inhibitors of chaperone heat shock protein 90. Journal of Medicinal Chemistry, 51 (3). pp. 373-375. ISSN 0022-2623

Graf, Christine and Niwa, Satoru and Mueller, Matthias and Kinzel, Bernd and Bornancin, Frederic (2008) Wild-type levels of ceramide and ceramide-1-phosphate in the retina of ceramide kinase-like-deficient mice. Biochemical and Biophysical Research Communications, 373 (1). pp. 159-163. ISSN 1090-2104

Graf, Christine and Niwa, Satoru and Mueller, Matthias and Kinzel, Bernd and Bornancin, Frederic (2008) Wild-type levels of ceramide and ceramide-1-phosphate in the retina of ceramide kinase-like-deficient mice. Biochemical and Biophysical Research Communications, 373 (1). pp. 159-163. ISSN 1090-2104

Graf, Christine and Zemann, Barbara and Rovina, Philipp and Urtz, Nicole and Schanzer, Andrea and Reuschel, Roland and Mechtcheriakova, Diana and Müller, Matthias and Fischer, Evelin and Reichel, Claudia and Huber, Susanna and Dawson, Janet and Meingassner, Josef and Billich, Andreas and Niwa, Satoru and Badegruber, Rudolf and Van Veldhoven, Paul P and Kinzel, Bernd and Baumruker, Thomas and Bornancin, Frederic (2008) Neutropenia with impaired immune response to Streptococcus pneumoniae in ceramide kinase-deficient mice. Journal of Immunology, 180 (5). pp. 3457-3466. ISSN 0022-1767

Grandl, Joerg and Hu, Hongzhen and Bandell, Michael and Bursulaya, Badry and Schmidt, Manuela and Petrus, Matthew and Patapoutian, Ardem (2008) Pore region of TRPV3 ion channel is specifically required for heat activation. Nature Neuroscience, 11 (9). pp. 1007-1013. ISSN 1546-1726

Grange, Wilfried and Duckely, Myriam and Husale, Sudhir and Jacob, Susan and Engel, Andreas and Hegner, Martin (2008) VirE2: a unique ssDNA-compacting molecular machine. PLoS Biology, 6 (2). e44. ISSN 1545-7885

Grohmann, Rainer and Schindler, Thomas Frederik (2008) Toward robust QSPR models: Synergistic utilization of robust regression and variable elimination. Journal of Computational Chemistry, 29 (6). pp. 847-860. ISSN 1096-987X

Grosshans, Bianka and Novick, Peter (2008) Identification and verification of Sro7p as an effector of the Sec4p Rab GTPase. Methods in Enzymology, 438. pp. 95-108. ISSN 0076-6879

Gryllos, Ioannis and Grifantini, Renata and Colaprico, Annalisa and Cary, Max E and Hakansson, Anders and Carey, David W and Suarez-Chavez, Maria and Kalish, Leslie A and Mitchell, Paul D and White, Gary L and Wessels, Michael R (2008) PerR confers phagocytic killing resistance and allows pharyngeal colonization by group A Streptococcus. PLoS pathogens, 4 (9). e1000145. ISSN 1553-7374

Gschwind, Hans-Peter and Waldmeier, Felix and Zollinger, Markus and Schweitzer, Alain and Grassberger, Maximilian (2008) Pimecrolimus: skin disposition after topical administration in minipigs in vivo and in human skin in vitro. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 33 (1). pp. 9-19. ISSN 0928-0987

Guenova, Emmanuella and Volz, Thomas and Sauer, Karin and Kaesler, Susanne and Müller, Martin R and Wölbing, Florian and Chen, KoMing and Schwaerzler, Christoph and Brossart, Peter and Röcken, Martin and Biedermann, Tilo (2008) IL-4-mediated fine tuning of IL-12p70 production by human DC. European Journal of Immunology, 38 (11). pp. 3138-3149. ISSN 0014-2980

Gulati, Pawan and Gaspers, Lawrence D and Dann, Stephen G and Joaquin, Manel and Nobukuni, Takahiro and Natt, Francois and Kozma, Sara C and Thomas, Andrew P and Thomas, George (2008) Amino acids activate mTOR complex 1 via Ca2+/CaM signaling to hVps34. Cell Metabolism, 7 (5). pp. 456-465. ISSN 1932-7420

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Hagman, Charlotte and Ricke, Darrell and Ewert, Stefan and Bek, Stephan and Falchetto, Rocco Angelo and Bitsch, Francis (2008) Absolute quantification of monoclonal antibodies in biofluids by liquid chromatography-tandem mass spectrometry. Analytical Chemistry, 80 (4). pp. 1290-1296. ISSN 0003-2700

Hagman, Charlotte and Ricke, Darrell and Ewert, Stefan and Bek, Stephan and Falchetto, Rocco Angelo and Bitsch, Francis (2008) Absolute quantification of monoclonal antibodies in biofluids by liquid chromatography-tandem mass spectrometry. Analytical Chemistry, 80 (4). pp. 1290-1296. ISSN 0003-2700

Halin, Cornelia and Fahrngruber, Hermann and Meingassner, Josef and Bold, Guido and Littlewood-Evans, Amanda and Stuetz, Anton and Detmar, Michael (2008) Inhibition of chronic and acute skin inflammation by treatment with a vascular endothelial growth factor receptor tyrosine kinase inhibitor. The American Journal of Pathology, 173 (1). pp. 265-277. ISSN 1525-2191

Hannon, Jason and Hoyer, Daniel (2008) Molecular biology of 5-HT receptors. Behavioural Brain Research, 195 (1). pp. 198-213. ISSN 1872-7549

Harris, Helen J and Farquhar, Michelle J and Mee, Christopher J and Davis, Christopher and Reynolds, Gary M and Jennings, Adam and Hu, Ke and Yuan, Fei and Deng, HongKui and Hubscher, Stefan G and Han, Jang H and Balfe, Peter and McKeating, Jane A (2008) CD81 and claudin 1 coreceptor association: role in hepatitis C virus entry. Journal of Virology, 82 (10). pp. 5007-5020. ISSN 1098-5514

He, Yan-Ling and Flannery, Brian and Campestrini, Joelle and Leon Reyes, Selene and Zinny, Miguel A and Ligueros-Saylan, Monica and Jarugula, Venkateswar (2008) Effect of food on the pharmacokinetics of a vildagliptin/metformin (50/1000 mg) fixed-dose combination tablet in healthy volunteers. Current Medical Research and Opinion, 24 (6). pp. 1703-1709. ISSN 1473-4877

He, Yan-Ling and Ligueros-Saylan, Monica and Sunkara, Gangadhar and Sabo, Ronald and Zhao, Charlie and Wang, Yibin and Campestrini, Joelle and Pommier, Francoise and Dole, Kiran and Marion, Alan and Dole, William and Howard, Danny (2008) Vildagliptin, a novel dipeptidyl peptidase IV inhibitor, has no pharmacokinetic interactions with the antihypertensive agents amlodipine, valsartan, and ramipril in healthy subjects. Journal of Clinical Pharmacology, 48 (1). pp. 85-95. ISSN 0091-2700

Heikenwalder, Mathias and Prinz, Marco and Zeller, Nicolas and Lang, Karl S and Junt, Tobias and Rossi, Simona and Tumanov, Alexei and Schmidt, Hauke and Priller, Josef and Flatz, Lukas and Rülicke, Thomas and Macpherson, Andrew J and Holländer, Georg A and Nedospasov, Sergei A and Aguzzi, Adriano (2008) Overexpression of lymphotoxin in T cells induces fulminant thymic involution. The American Journal of Pathology, 172 (6). pp. 1555-1570. ISSN 1525-2191

Hertig, Alexandre and Lefevre, Guillaume and Toumi, Karine and Rondeau, Eric and Capeau, Jacqueline and Uzan, Serge and Berkane, Nadia (2008) Soluble endoglin levels during normotensive and hypertensive pregnancies. European journal of obstetrics, gynecology, and reproductive biology, 140 (1). pp. 138-140. ISSN 0301-2115

Hiestand, Peter and Rausch, Martin and Meier, Daniela and Foster, Carolyn-Ann (2008) Ascomycete derivative to MS therapeutic: S1P receptor modulator FTY720. Progress in Drug Research. Fortschritte der Arzneimittelforschung. Progrès des recherches pharmaceutiques, 66. pp. 361-381. ISSN 0071-786X

Hilleringmann, Markus and Giusti, Fabiola and Baudner, Barbara and Masignani, Vega and Covacci, Antonello and Rappuoli, Rino and Barocchi, Michèle A and Ferlenghi, Ilaria (2008) Pneumococcal pili are composed of protofilaments exposing adhesive clusters of Rrg A. PLoS Pathogens, 4 (3). e1000026. ISSN 1553-7374

Hintersteiner, Martin and Auer, Manfred (2008) Single-bead, single-molecule, single-cell fluorescence: technologies for drug screening and target validation. Annals of the New York Academy of Sciences, 1130. pp. 1-11. ISSN 0077-8923

Hirasawa, Ryutaro and Chiba, Hatsune and Kaneda, Masahiro and Tajima, Shoji and Li, En and Jaenisch, Rudolf and Sasaki, Hiroyuki (2008) Maternal and zygotic Dnmt1 are necessary and sufficient for the maintenance of DNA methylation imprints during preimplantation development. Genes & Development, 22 (12). pp. 1607-1616. ISSN 0890-9369

Hoegenauer, Klemens and Billich, Andreas and Pally, Charles and Streiff, Markus and Wagner, Beatrix and Welzenbach, Karl and Nussbaumer, Peter (2008) Phosphorylation by sphingosine kinase 2 is essential for in vivo potency of FTY720 analogues. ChemMedChem, 3 (7). pp. 1027-1029. ISSN 1860-7187

Hogan, Christopher and Simons, Sarah and Zhang, Haiyan and Burdick, Debra (2008) Living with Irresolute Cell Lines in an Automated World. Journal of the Association for Laboratory Automation, 13. pp. 159-167. ISSN 1540-2452

Holden, Neil and Squires, Paul E and Kaur, Manminder and Bland, Rosemary and Jones, Carol and Newton, Robert (2008) Phorbol ester-stimulated NF-kappaB-dependent transcription: roles for isoforms of novel protein kinase C. Cellular Signalling, 20 (7). pp. 1338-1348. ISSN 0898-6568

Holmes, Joseph and Martin, Daniel and Ramsay, C and Ypma, E and Oster, P (2008) Combined administration of serogroup B meningococcal vaccine and conjugated serogroup C meningococcal vaccine is safe and immunogenic in college students. Epidemiology and Infection, 136 (6). pp. 790-799. ISSN 0950-2688

Huang, Bing S and White, Roselyn A and Ahmad, Monir and Jeng, Arco and Leenen, Frans H H (2008) Central infusion of aldosterone synthase inhibitor prevents sympathetic hyperactivity and hypertension by central Na+ in Wistar rats. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology, 295 (1). R166-R172. ISSN 0363-6119

Huang, Bing S and White, Roselyn A and Ahmad, Monir and Jeng, Arco and Leenen, Frans H H (2008) Central infusion of aldosterone synthase inhibitor prevents sympathetic hyperactivity and hypertension by central Na+ in Wistar rats. American Journal of Physiology. Regulatory, integrative and comparative physiology, 295 (1). R166-R172. ISSN 0363-6119

Huss, Jon and Orozco, Camilo and Goodale, James and Wu, Chunlei and Batalov, Sergei and Vickers, Tim and Valafar, Faramarz and Su, Andrew (2008) A gene wiki for community annotation of gene function. PLoS Biology, 6 (7). e175. ISSN 1545-7885

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Irie, Osamu and Ehara, Takeru and Iwasaki, Atsuko and Yokokawa, Fumiaki and Sakaki, Junichi and Hirao, Hajime and Kanazawa, Takanori and Teno, Naoki and Horiuchi, Miyuki and Umemura, Ichiro and Gunji, Hiroki and Masuya, Keiichi and Hitomi, Yuko and Iwasaki, Genji and Nonomura, Kazuhiko and Tanabe, Keiko and Fukaya, Hiroaki and Kosaka, Takatoshi and Snell, Chris and Hallett, Allan (2008) Discovery of selective and nonpeptidic cathepsin S inhibitors. Bioorganic & Medicinal Chemistry Letters, 18 (14). pp. 3959-3962. ISSN 1464-3405

Issa, Razao and Sorrentino, Rosalinda and Sukkar, Maria B and Sriskandan, Shiranee and Chung, Kian Fan and Mitchell, Jane A (2008) Differential regulation of CCL-11/eotaxin-1 and CXCL-8/IL-8 by gram-positive and gram-negative bacteria in human airway smooth muscle cells. Respiratory Research, 9. p. 30. ISSN 1465-993X

Iwata, Nobuhisa and Tsubuki, Satoshi and Higuchi, Makoto and Staufenbiel, Matthias and Saido, Takaomi C (2008) Pathological significance of AbN3pyroglutamate accumulation in Alzheimer’s disease. Neuroscience Research, 61 (Supplement 1). S122. ISSN 0921-8696

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Jensen, Michael Rugaard and Ide, Susan and Brueggen, Josef and Schoepfer, Joseph and Motwani, Monica and Wang, X and Radimerski, Thomas and Quadt, Cornelia and Garcia-Echeverria, Carlos and Chene, Patrick (2008) Pharmakokinetic/phamacodynamic relationship in human xenograft models and PBMC’s treated with the Hsp90 inhibitor NVP-AUY922. European Journal of Cancer Supplements, 6 (12). p. 50. ISSN 1359-6349

Jensen, Michael and Schoepfer, Joseph and Radimerski, Thomas and Massey, Andrew and Guy, Chantale and Brueggen, Josef and Quadt, Cornelia and Buckler, Alan and Cozens, Robert and Drysdale, Martin and Garcia-Echeverria, Carlos and Chène, Patrick (2008) NVP-AUY922: a small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models. Breast Cancer Research, 10 (2). R33. ISSN 1465-5411

Jensen, Michael Rugaard and Schoepfer, Joseph and Radimerski, Thomas and Massey, Andrew and Guy, Chantale and Brueggen, Josef and Quadt, Cornelia and Buckler, Alan and Cozens, Robert and Drysdale, Martin J and Garcia-Echeverria, Carlos and Chene, Patrick (2008) NVP-AUY922: a small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models. Breast Cancer Research : BCR, 10 (2). R33. ISSN 1465-542X

Ji, Bin and Maeda, Jun and Sawada, Makoto and Ono, Maiko and Okauchi, Takashi and Inaji, Motoki and Zhang, Ming-Rong and Suzuki, Kazutoshi and Ando, Kiyoshi and Staufenbiel, Matthias and Trojanowski, John Q and Lee, Virginia M Y and Higuchi, Makoto and Suhara, Tetsuya (2008) Imaging of peripheral benzodiazepine receptor expression as biomarkers of detrimental versus beneficial glial responses in mouse models of Alzheimer's and other CNS pathologies. The Journal of Neuroscience: the official journal of the Society for Neuroscience, 28 (47). pp. 12255-12267. ISSN 1529-2401

Johansson, Gunnar and Mahller, Yonatan Y and Collins, Margaret H and Kim, Mi-Ok and Nobukuni, Takahiro and Perentesis, John and Cripe, Timothy P and Lane, Heidi and Kozma, Sara C and Thomas, George and Ratner, Nancy (2008) Effective in vivo targeting of the mammalian target of rapamycin pathway in malignant peripheral nerve sheath tumors. Molecular Cancer Therapeutics, 7 (5). pp. 1237-1245. ISSN 1535-7163

Jones, Brendan and Su, Hui and Bhat, Audesh and Lei, Hong and Bajko, Jeffrey and Hevi, Sarah and Baltus, Gretchen and Kadam, Shilpa and Zhai, Huili and Valdez, Reginald and Gonzalo, Susana and Zhang, Yi and Li, En and Chen, Taiping (2008) The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure. PLoS Genetics, 4 (9). e1000190. ISSN 1553-7404

Juckem, Laura K and Boehme, Karl W and Feire, Adam and Compton, Teresa (2008) Differential initiation of innate immune responses induced by human cytomegalovirus entry into fibroblast cells. Journal of Immunology (Baltimore, Md. : 1950), 180 (7). pp. 4965-4977. ISSN 0022-1767

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Karmouty Quintana, Harry and Ble, Francois-Xavier and Cannet, Catherine and Zurbruegg, Stefan and Fozard, John R. and Page, Christopher and Beckmann, Nicolau (2008) In vivo pharmacological evaluation of compound 48/80-induced airways oedema by MRI. British Journal of Pharmacology, 154 (5). pp. 1063-1072. ISSN 0007-1188

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Klionsky, Daniel J and Abeliovich, Hagai and Agostinis, Patrizia and Agrawal, Devendra K and Aliev, Gjumrakch and Askew, David S and Baba, Misuzu and Baehrecke, Eric H and Bahr, Ben A and Ballabio, Andrea and Bamber, Bruce A and Bassham, Diane C and Bergamini, Ettore and Bi, Xiaoning and Biard-Piechaczyk, Martine and Blum, Janice S and Bredesen, Dale E and Brodsky, Jeffrey L and Brumell, John H and Brunk, Ulf T and Bursch, Wilfried and Camougrand, Nadine and Cebollero, Eduardo and Cecconi, Francesco and Chen, Yingyu and Chin, Lih-Shen and Choi, Augustine and Chu, Charleen T and Chung, Jongkyeong and Clarke, Peter G H and Clark, Robert S B and Clarke, Steven G and Clavé, Corinne and Cleveland, John L and Codogno, Patrice and Colombo, María I and Coto-Montes, Ana and Cregg, James M and Cuervo, Ana Maria and Debnath, Jayanta and Demarchi, Francesca and Dennis, Patrick B and Dennis, Phillip A and Deretic, Vojo and Devenish, Rodney J and Di Sano, Federica and Dice, J Fred and Difiglia, Marian and Dinesh-Kumar, Savithramma and Distelhorst, Clark W and Djavaheri-Mergny, Mojgan and Dorsey, Frank C and Dröge, Wulf and Dron, Michel and Dunn, William A and Duszenko, Michael and Eissa, N Tony and Elazar, Zvulun and Esclatine, Audrey and Eskelinen, Eeva-Liisa and Fésüs, László and Finley, Kim D and Fuentes, José M and Fueyo, Juan and Fujisaki, Kozo and Galliot, Brigitte and Gao, Fen-Biao and Gewirtz, David A and Gibson, Spencer B and Gohla, Antje and Goldberg, Alfred L and Gonzalez, Ramon and González-Estévez, Cristina and Gorski, Sharon and Gottlieb, Roberta A and Häussinger, Dieter and He, You-Wen and Heidenreich, Kim and Hill, Joseph A and Høyer-Hansen, Maria and Hu, Xun and Huang, Wei-Pang and Iwasaki, Akiko and Jäättelä, Marja and Jackson, William T and Jiang, Xuejun and Jin, Shengkan and Johansen, Terje and Jung, Jae U and Kadowaki, Motoni and Kang, Chanhee and Kelekar, Ameeta and Kessel, David H and Kiel, Jan A K W and Kim, Hong Pyo and Kimchi, Adi and Kinsella, Timothy J and Kiselyov, Kirill and Kitamoto, Katsuhiko and Knecht, Erwin and Komatsu, Masaaki and Kominami, Eiki and Kondo, Seiji and Kovács, Attila L and Kroemer, Guido and Kuan, Chia-Yi and Kumar, Rakesh and Kundu, Mondira and Landry, Jacques and Laporte, Marianne and Le, Weidong and Lei, Huan-Yao and Lenardo, Michael J and Levine, Beth and Lieberman, Andrew and Lim, Kah-Leong and Lin, Fu-Cheng and Liou, Willisa and Liu, Leroy F and Lopez-Berestein, Gabriel and López-Otín, Carlos and Lu, Bo and Macleod, Kay F and Malorni, Walter and Martinet, Wim and Matsuoka, Ken and Mautner, Josef and Meijer, Alfred J and Meléndez, Alicia and Michels, Paul and Miotto, Giovanni and Mistiaen, Wilhelm P and Mizushima, Noboru and Mograbi, Baharia and Monastyrska, Iryna and Moore, Michael N and Moreira, Paula I and Moriyasu, Yuji and Motyl, Tomasz and Münz, Christian and Murphy, Leon and Naqvi, Naweed I and Neufeld, Thomas P and Nishino, Ichizo and Nixon, Ralph A and Noda, Takeshi and Nürnberg, Bernd and Ogawa, Michinaga and Oleinick, Nancy L and Olsen, Laura J and Ozpolat, Bulent and Paglin, Shoshana and Palmer, Glen E and Papassideri, Issidora and Parkes, Miles and Perlmutter, David H and Perry, George and Piacentini, Mauro and Pinkas-Kramarski, Ronit and Prescott, Mark and Proikas-Cezanne, Tassula and Raben, Nina and Rami, Abdelhaq and Reggiori, Fulvio and Rohrer, Bärbel and Rubinsztein, David C and Ryan, Kevin M and Sadoshima, Junichi and Sakagami, Hiroshi and Sakai, Yasuyoshi and Sandri, Marco and Sasakawa, Chihiro and Sass, Miklós and Schneider, Claudio and Seglen, Per O and Seleverstov, Oleksandr and Settleman, Jeffrey and Shacka, John J and Shapiro, Irving M and Sibirny, Andrei and Silva-Zacarin, Elaine C M and Simon, Hans-Uwe and Simone, Cristiano and Simonsen, Anne and Smith, Mark A and Spanel-Borowski, Katharina and Srinivas, Vickram and Steeves, Meredith and Stenmark, Harald and Stromhaug, Per E and Subauste, Carlos S and Sugimoto, Seiichiro and Sulzer, David and Suzuki, Toshihiko and Swanson, Michele S and Tabas, Ira and Takeshita, Fumihiko and Talbot, Nicholas J and Tallóczy, Zsolt and Tanaka, Keiji and Tanaka, Kozo and Tanida, Isei and Taylor, Graham S and Taylor, J Paul and Terman, Alexei and Tettamanti, Gianluca and Thompson, Craig B and Thumm, Michael and Tolkovsky, Aviva M and Tooze, Sharon A and Truant, Ray and Tumanovska, Lesya V and Uchiyama, Yasuo and Ueno, Takashi and Uzcátegui, Néstor L and van der Klei, Ida and Vaquero, Eva C and Vellai, Tibor and Vogel, Michael W and Wang, Hong-Gang and Webster, Paul and Wiley, John W and Xi, Zhijun and Xiao, Gutian and Yahalom, Joachim and Yang, Jin-Ming and Yap, George and Yin, Xiao-Ming and Yoshimori, Tamotsu and Yu, Li and Yue, Zhenyu and Yuzaki, Michisuke and Zabirnyk, Olga and Zheng, Xiaoxiang and Zhu, Xiongwei and Deter, Russell L (2008) Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes. Autophagy, 4 (2). pp. 151-175. ISSN 1554-8635

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Kurash, Yuliya and Lei, Hong and Shen, Qiong and Marston, Wendy and Granda, Brian and Fan, Hong and Wall, Daniel and Li, En and Gaudet, Francois (2008) Methylation of p53 by Set7/9 mediates p53 acetylation and activity in vivo. Molecular Cell, 29 (3). pp. 392-400. ISSN 1097-2765

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Mac Sweeney, Aengus and Gil Parrado, Shirley and Vinzenz, Daniela and Bernardi, Anna and Hein, Andreas and Bodendorf, Ursula and Erbel, Paulus and Logel, Claude and Gerhartz, Bernd (2008) Structural basis for the substrate specificity of bone morphogenetic protein 1/tolloid-like metalloproteases. Journal of Molecular Biology, 384 (1). pp. 228-239. ISSN 1089-8638

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Maiso, Patricia and Ocio, Enrique M and Garayoa, Mercedes and Montero, Juan C and Hofmann, Francesco and Garcia-Echeverria, Carlos and Zimmermann, Johann and Pandiella, Atanasio and San Miguel, Jesus F (2008) The insulin-like growth factor-I receptor inhibitor NVP-AEW541 provokes cell cycle arrest and apoptosis in multiple myeloma cells. British Journal of Haematology, 141 (4). pp. 470-482. ISSN 1365-2141

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Nussbaumer, Peter and Hornillos Gomez-Recuero, Valentin and Ghobrial, Michael and Ullrich, Thomas (2008) An efficient, one-pot synthesis of various ceramide 1-phosphates from sphingosine 1-phosphate. Chemistry and Physics of Lipids, 151 (2). pp. 125-128. ISSN 0009-3084

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Puschendorf, Mareike and Terranova, Remi and Boutsma, Erwin and Mao, Xiaohong and Isono, Kyo-ichi and Brykczynska, Urszula and Kolb, Carolin and Otte, Arie P and Koseki, Haruhiko and Orkin, Stuart H and van Lohuizen, Maarten and Peters, Antoine (2008) PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos. Nature Genetics, 40 (4). pp. 411-420. ISSN 1546-1718

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Rao, Srinivasa and Camacho, Luis and Tan, Bee Huat and Boon, Calvin and Russel, David G and Dick, Thomas and Pethe, Kevin (2008) Recombinase-based reporter system and antisense technology to study gene expression and essentiality in hypoxic nonreplicating mycobacteria. FEMS Microbiology Letters, 284 (1). pp. 68-75. ISSN 0378-1097

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Rines, Daniel and Gomez-Ferreira, Maria Ana and Zhou, Yingyao and De Jesus, Paul and Grob, Seanna and Batalov, Sergei and Labow, Mark and Huesken, Dieter and Mickanin, Craig and Hall, Jonathan and Reinhardt, Mischa and Natt, Francois and Lange, Joerg and Sharp, David J and Chanda, Sumit and Caldwell, Jeremy (2008) Whole genome functional analysis identifies novel components required for mitotic spindle integrity in human cells. Genome Biology, 9 (2). R44. ISSN 1465-6914

Rines, Daniel R and Gomez-Ferreria, Maria Ana and Zhou, Yingyao and DeJesus, Paul and Grob, Seanna and Batalov, Serge and Labow, Mark and Huesken, Dieter and Mickanin, Craig and Hall, Jonathan and Reinhardt, Mischa and Natt, Francois and Lange, Joerg and Sharp, David J and Chanda, Sumit K and Caldwell, Jeremy S (2008) Whole genome functional analysis identifies novel components required for mitotic spindle integrity in human cells. Genome biology, 9 (2). R44. ISSN 1465-6914

Ritter, Veronique O. and Thuering, Barbara and Saint-Mezard, Pierre and Luong-Nguyen, Ngoc-Hong and Seltenmeyer, Yves and Junker, Uwe and Fournier, Brigitte and Susa Spring, Mira and Morvan, Frederic (2008) Follicle-stimulating hormone does not impact male bone mass in vivo or human male osteoclasts in vitro. Calcified Tissue International, 82 (5). pp. 383-391. ISSN 0171-967X

Rockx, Barry and Corti, Davide and Donaldson, Eric and Sheahan, Timothy and Stadler, Konrad and Lanzavecchia, Antonio and Baric, Ralph (2008) Structural basis for potent cross-neutralizing human monoclonal antibody protection against lethal human and zoonotic severe acute respiratory syndrome coronavirus challenge. Journal of Virology, 82 (7). pp. 3220-3235. ISSN 1098-5514

Rooks, Daniel (2008) Talking to patients with fibromyalgia about physical activity and exercise. Current Opinion in Rheumatology, 20 (2). pp. 208-212. ISSN 1040-8711

Rooks, Daniel (2008) Talking to patients with fibromyalgia about physical activity and exercise. Current Opinion in Rheumatology, 20 (2). pp. 208-212. ISSN 1040-8711

Rucci, Nadia and Susa, Maria and Teti, Anna (2008) Inhibition of protein kinase c-Src as a therapeutic approach for cancer and bone metastases. Anti-cancer Agents in Medicinal Chemistry, 8 (3). pp. 342-349. ISSN 1871-5206

Russell, Colin A and Jones, Terri and Barr, Ian G and Cox, Nancy J and Garten, Rebecca J and Gregory, Vicky and Gust, Ian D and Hampson, Alan W and Hay, Alan J and Hurt, Aeron C and de Jong, Jan C and Kelso, Anne and Klimov, Alexander I and Kageyama, Tsutomu and Komadina, Naomi and Lapedes, Alan S and Lin, Yi P and Mosterin, Ana and Obuchi, Masatsugu and Odagiri, Takato and Osterhaus, Albert D M E and Rimmelzwaan, Guus F and Shaw, Michael W and Skepner, Eugene and Stohr, Klaus and Tashiro, Masato and Fouchier, Ron A M and Smith, Derek J (2008) The global circulation of seasonal influenza A (H3N2) viruses. Science (New York, N.Y.), 320 (5874). pp. 340-346. ISSN 1095-9203

Rutjens, Erik and Vermeulen, Joost and Verstrepen, Babs and Hofman, Sam and Prins, Jan M and Srivastava, Indresh and Heeney, Jonathan L and Koopman, Gerrit (2008) Chimpanzee CD4+ T cells are relatively insensitive to HIV-1 envelope-mediated inhibition of CD154 up-regulation. European Journal of Immunology, 38 (4). pp. 1164-1172. ISSN 0014-2980

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Salie, Rishard and Li, Haitao and Jiang, Xi and Rowe, David W and Kalajzic, Ivo and Susa Spring, Mira (2008) A rapid, nonradioactive in situ hybridization technique for use on cryosectioned adult mouse bone. Calcified Tissue International, 83 (3). pp. 212-221. ISSN 0171-967X

Sari-Sarraf, Farid and Pomposiello, Silvia and Laurent, Didier (2008) Acute impairment of rat renal function by L -NAME as measured using dynamic MRI. Magnetic Resonance Materials in Physics, Biology and Medicine, 21 (4). pp. 291-297. ISSN 0968-5243

Sato, Hiroyasu and Kato, Rina and Isogai, Yuki and Saka, Go-ichi and Ohtsuki, Mitsuhiro and Taketomi, Yoshitaka and Yamamoto, Kei and Tsutsumi, Kae and Yamada, Joe and Masuda, Seiko and Ishikawa, Yukio and Ishii, Toshiharu and Kobayashi, Tetsuyuki and Ikeda, Kazutaka and Taguchi, Ryo and Hatakeyama, Shinji and Hara, Shuntaro and Kudo, Ichiro and Itabe, Hiroyuki and Murakami, Makoto (2008) Analyses of group III secreted phospholipase A2 transgenic mice reveal potential participation of this enzyme in plasma lipoprotein modification, macrophage foam cell formation, and atherosclerosis. The Journal of Biological Chemistry, 283 (48). pp. 33483-33497. ISSN 0021-9258

Saul, Allan and Rappuoli, Rino (2008) The Novartis Vaccines Institute for Global Health: a new initiative for developing vaccines for neglected diseases in developing countries. Journal of Infection in Developing Countries, 2 (2). pp. 154-155. ISSN 1972-2680

Savage, Ronald E and Tyler, Andrew and Miao, Xiu-Sheng and Chan, Thomas C K (2008) Identification of a novel glucosylsulfate conjugate as a metabolite of 3,4-dihydro-2,2-dimethyl-2H-naphtho[1,2-b]pyran-5,6-dione (ARQ 501, beta-lapachone) in mammals. Drug Metabolism and Disposition: the biological fate of chemicals, 36 (4). pp. 753-758. ISSN 1521-009X

Schedlbauer, Andreas and Auer, Renate and Ledolter, Karin and Tollinger, Martin and Kloiber, Karin and Lichtenecker, Roman and Ruedisser, Simon and Hommel, Ulrich and Schmid, Walther and Konrat, Robert and Kontaxis, Georg (2008) Direct methods and residue type specific isotope labeling in NMR structure determination and model-driven sequential assignment. Journal of Biomolecular NMR, 42 (2). pp. 111-127. ISSN 0925-2738

Scheiber, Josef and Jenkins, Jeremy and Bender, Andreas and Whitebread, Steven and Hamon, Jacques and Urban, Laszlo and Azzaoui, Kamal and Glick, Meir and Davies, John (2008) Side effect profile prediction - early addressing of big pharma's worst nightmare. Chemistry Central Journal, 2 (Suppl ). S4. ISSN 1752-153X

Schindeler, Aaron and Morse, Alyson and Harry, Lorraine and Godfrey, Craig and Mikulec, Kathy and McDonald, Michelle and Gasser, Juerg Andreas and Little, David G (2008) Models of tibial fracture healing in normal and Nf1-deficient mice. Journal of Orthopaedic Research : official publication of the Orthopaedic Research Society, 26 (8). pp. 1053-1060. ISSN 1554-527X

Schlapbach, Achim and Feifel, Roland and Hawtin, Stuart and Heng, Richard and Koch, Guido and Moebitz, Henrik and Revesz, Laszlo and Scheufler, Clemens and Velcicky, Juraj and Waelchli, Rudolf and Huppertz, Christine (2008) Pyrrolo-pyrimidones: a novel class of MK2 inhibitors with potent cellular activity. Bioorganic & Medicinal Chemistry Letters, 18 (23). pp. 6142-6146. ISSN 1464-3405

Schmid, Herbert (2008) Pasireotide (SOM230): Development, mechanism of action and potential applications. Molecular and Cellular Endocrinology, 286 (1-2). pp. 69-74. ISSN 0303-7207

Schmid, Herbert (2008) Pasireotide (SOM230): Development, mechanism of action and potential applications. Molecular and Cellular Endocrinology, 286 (1-2). pp. 69-74. ISSN 0303-7207

Schmid, Ralf and Tsujimoto, Naomi and Qu, Qiang and Lei, Hong and Li, En and Chen, Taiping and Blaustein, Cecile (2008) A methyl-CpG-binding protein 2-enhanced green fluorescent protein reporter mouse model provides a new tool for studying the neuronal basis of Rett syndrome. Neuroreport, 19 (4). pp. 393-398. ISSN 0959-4965

Schmid, Ralf S and Tsujimoto, Naomi and Qu, Qiang and Lei, Hong and Li, En and Chen, Taiping and Blaustein, Cecile (2008) A methyl-CpG-binding protein 2-enhanced green fluorescent protein reporter mouse model provides a new tool for studying the neuronal basis of Rett syndrome. Neuroreport, 19 (4). pp. 393-398. ISSN 0959-4965

Schrenk-Siemens, Katrin and Perez-Alcala, Siro and Richter, Jens and Lacroix, Emmanuel and Rahuel, Joseph and Korte, Martin and Müller, Ulrike and Barde, Yves-Alain and Bibel, Miriam (2008) Embryonic stem cell-derived neurons as a cellular system to study gene function: lack of amyloid precursor proteins APP and APLP2 leads to defective synaptic transmission. Stem Cells (Dayton, Ohio), 26 (8). pp. 2153-2163. ISSN 1549-4918

Schubart, Anna and Seabrook, Tim and Rausch, Martin and Mir, Anis Khusro (2008) Oral fingolimod (FTY720) suppresses established EAE and allows remyelination. Journal of Neuroimmunology, 203 (2). p. 248. ISSN 0165-5728

Scuto, Anna and Kirschbaum, Mark and Kowolik, Claudia and Kretzner, Leo and Juhasz, Agnes and Atadja, Paul and Pullarkat, Vinod and Bhatia, Ravi and Forman, Stephen and Yen, Yun and Jove, Richard (2008) The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph- acute lymphoblastic leukemia cells. Blood, 111 (10). pp. 5093-5100. ISSN 1528-0020

Sechaud, R and Robeva, A and Belleli, R and Balez, S (2008) Absence of an effect of a single-dose deferasirox on the steady-state pharmacokinetics of digoxin. International journal of clinical pharmacology and therapeutics, 46 (10). pp. 519-526. ISSN 0946-1965

Sechaud, Romain and Robeva, Anna and Belleli, Rossella and Balez, Sebastien (2008) Absence of an effect of a single-dose deferasirox on the steady-state pharmacokinetics of digoxin. International journal of clinical pharmacology and therapeutics, 46 (10). pp. 519-526. ISSN 0946-1965

Sechaud, Romain and Robeva, Anna and Belleli, Rossella and Balez, Sebastien (2008) Absolute oral bioavailability and disposition of deferasirox in healthy human subjects. Journal of clinical pharmacology, 48 (8). pp. 919-925. ISSN 0091-2700

Senechal, Yann and Kelly, Peter and Dev, Kumlesh K. (2008) Amyloid precursor protein knockout mice show age-dependent deficits in passive avoidance learning. Behavioural Brain Research, 186 (1). pp. 126-132. ISSN 0166-4328

Senechal, Yann and Prut, Laetitia and Kelly, Peter and Staufenbiel, Matthias and Natt, Francois and Hoyer, Daniel and Wiessner, Christoph and Dev, Kumlesh K. (2008) Increased exploratory activity of APP23 mice in a novel environment is reversed by siRNA. Brain Research, 1243. pp. 124-133. ISSN 1872-6240

Serluca-Aegerter, Fabrizio (2008) Development of the proepicardial organ in the zebrafish. Developmental Biology, 315 (1). pp. 18-27. ISSN 1095-564X

Serluca-Aegerter, Fabrizio (2008) Development of the proepicardial organ in the zebrafish. Developmental Biology, 315 (1). pp. 18-27. ISSN 1095-564X

Serra, Alessandro and Nuti, Sandra and Tavarini, Simona and Sammicheli, Chiara and Rosa, Domenico and Saletti, Giulietta and Soldaini, Elisabetta and Abrignani, Sergio and Wack, Andreas (2008) Coligation of the hepatitis C virus receptor CD81 with CD28 primes naive T lymphocytes to acquire type 2 effector function. Journal of Immunology (Baltimore, Md. : 1950), 181 (1). pp. 174-185. ISSN 0022-1767

Serra, Violeta and Markman, Ben and Scaltriti, Maurizio and Eichhorn, Pieter J A and Valero, Vanesa and Guzman, Marta and Botero, Maria Luisa and Llonch, Elisabeth and Atzori, Francesco and Di Cosimo, Serena and Maira, Michel and Garcia-Echeverria, Carlos and Parra, Josep Lluis and Arribas, Joaquin and Baselga, José (2008) NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations. Cancer Research, 68 (19). pp. 8022-8030. ISSN 1538-7445

Seubert, Anja and Monaci, Elisabetta and Pizza, Mariagrazia and O'Hagan, Derek T and Wack, Andreas (2008) The adjuvants aluminum hydroxide and MF59 induce monocyte and granulocyte chemoattractants and enhance monocyte differentiation toward dendritic cells. Journal of Immunology (Baltimore, Md. : 1950), 180 (8). pp. 5402-5412. ISSN 0022-1767

Shah, J Jina and Maloney, Susan A and Liu, Yecai and Flagg, Elaine W and Johnston, Stephanie P and Young, Suzanna A and Weston, Robert and Merritt, Samuel and Wilkins, Patricia P and Keane, Vincent and Calderon, Jaime and Sharp, Donald J and Causer, Louise and Maguire, James H and Cetron, Martin S (2008) Evaluation of the impact of overseas pre-departure treatment for infection with intestinal parasites among Montagnard refugees migrating from Cambodia to North Carolina. The American Journal of Tropical Medicine and Hygiene, 78 (5). pp. 754-759. ISSN 1476-1645

Shao, Wenlin and Growney, Joseph and O'Connor, Gregory and Feng, Yun and Scher, H and Yao, Yao and Fawell, Stephen and Atadja, Peter (2008) Potent anticancer activity of panobinostat (LBH589) in models of hormone-refractory prostate cancer (HRPC): targeting the androgen receptor. European Journal of Cancer Supplements, 6 (12). p. 52. ISSN 1359-6349

Shen, Xiaohua and Liu, Yingchun and Hsu, Yu-Jung and Fujiwara, Yuko and Kim, Jonghwan and Mao, Xiaohong and Yuan, Guo-Cheng and Orkin, Stuart H (2008) EZH1 mediates methylation on histone H3 lysine 27 and complements EZH2 in maintaining stem cell identity and executing pluripotency. Molecular cell, 32 (4). pp. 491-502. ISSN 1097-4164

Shi, Leming and Jones, Wendell and Jensen, Roderick and Harris, Stephen and Perkins, Roger and Goodsaid, Federico and Guo, Lei and Croner, Lisa and Boysen, Cecilie and Fang, Hong and Qian, Feng and Amur, Shashi and Bao, Wenjun and Barbacioru, Catalin and Bertholet, Vincent and Cao, Xiaoxi and Chu, Tzu-Ming and Collins, Patrick and Fan, Xiao-hui and Frueh, Felix and Fuscoe, James and Han, jing and Guo, Xu and Herman, Damir and Hong, Huixiao and Kawasaki, Ernest and Li, Quan-Zhen and Luo, Yuling and Ma, Yunqing and Mei, Nan and Peterson, Ron and Puri, Raj (2008) The balance of reproducibility, sensitivity, and specificity of lists of differentially expressed genes in microarray studies. BMC Bioinformatics, 9 (Suppl ). S10. ISSN 1471-2105

Shibui, Takeo and Higo, Yukari and Tsutsui, Takeo W and Uchida, Minoru and Oshimura, Mitsuo and Barrett, James and Tsutsui, Takeki (2008) Changes in expression of imprinted genes following treatment of human cancer cell lines with non-mutagenic or mutagenic carcinogens. International Journal of Oncology, 33 (2). pp. 351-360. ISSN 1019-6439

Shua-Haim, Joshua and Smith, Juanita and Picard, Franck and Sedek, Greg and Athalye, Sandeep and Pommier, Françoise and Lefevre, Gilbert (2008) Steady-state pharmacokinetics of rivastigmine in patients with mild to moderate Alzheimer's disease not affected by co-administration of memantine: an open-label, crossover, single-centre study. Clinical drug investigation, 28 (6). pp. 361-374. ISSN 1173-2563

Siegl, Stephanie and Flor, Peter Josef and Fendt, Markus (2008) Amygdaloid metabotropic glutamate receptor subtype 7 is involved in the acquisition of conditioned fear. Neuroreport, 19 (11). pp. 1147-1150. ISSN 0959-4965

Siegl, Stephanie and Flor, Peter Josef and Fendt, Markus (2008) Amygdaloid metabotropic glutamate receptor subtype 7 is involved in the acquisition of conditioned fear. Neuroreport, 19 (11). pp. 1147-1150. ISSN 0959-4965

Siehler Wagner, Sandra (2008) Cell-based assays in GPCR drug discovery. Biotechnology Journal, 3 (4). pp. 471-483. ISSN 1860-7314

Siehler Wagner, Sandra and Nunn, Caroline and Hannon, Jason and Feuerbach, Dominik and Hoyer, Daniel (2008) Pharmacological profile of somatostatin and cortistatin receptors. Molecular and Cellular Endocrinology, 286 (1-2). pp. 26-34. ISSN 0303-7207

Siehler Wagner, Sandra and Nunn, Caroline and Hannon, Jason and Feuerbach, Dominik and Hoyer, Daniel (2008) Pharmacological profile of somatostatin and cortistatin receptors. Molecular and Cellular Endocrinology, 286 (1-2). pp. 26-34. ISSN 0303-7207

Simonen, Marjo and Ibig-Rehm, Yvonne and Hofmann, Gabriele and Zimmermann, Johann and Albrecht, Genevieve and Magnier, Maxime and Heidinger-Millot, Valerie and Gabriel, Daniela (2008) High-content assay to study protein prenylation. Journal of Biomolecular Screening : the official journal of the Society for Biomolecular Screening, 13 (6). pp. 456-467. ISSN 1087-0571

Skaanderup, Philip and Jensen, Thomas (2008) Synthesis of the macrocyclic core of (-)-pladienolide B. Organic Letters, 10 (13). pp. 2821-2824. ISSN 1523-7060

Skaanderup, Philip and Jensen, Thomas (2008) Synthesis of the macrocyclic core of (-)-pladienolide B. Organic Letters, 10 (13). pp. 2821-2824. ISSN 1523-7060

Song, Pingfang and Sekhon, Harmanjatinder S and Fu, Xiao Wen and Maier, Michelle and Jia, Yibing and Duan, Jie and Proskosil, Becky J and Gravett, Courtney and Lindstrom, Jon and Mark, Gregory P and Saha, Saurabh and Spindel, Eliot R (2008) Activated cholinergic signaling provides a target in squamous cell lung carcinoma. Cancer Research, 68 (12). pp. 4693-4700. ISSN 1538-7445

Soon, E and Holmes, Alan and Toshner, M and Treacy, C and Suntharalingam, J and Sheares, K and Budd, David and Pepke-Zaba, J and Morrell, N W (2008) Circulating Cytoking Profiles in Patients with Chronic Thromboembolic Pulmonary Hypertension and Response to Pulmonary Endarterectomy. Thorax, 63 (Supplement 7). A43. ISSN 0040-6376

Srivastava, Indresh K and Kan, Elaine and Sun, Yide and Sharma, Victoria A and Cisto, Jimna and Burke, Brian and Lian, Ying and Hilt, Susan and Biron, Zohar and Hartog, Karin and Stamatatos, Leonidas and Diaz-Avalos, Ruben and Cheng, R Holland and Ulmer, Jeffrey and Barnett, Susan W (2008) Comparative evaluation of trimeric envelope glycoproteins derived from subtype C and B HIV-1 R5 isolates. Virology, 372 (2). pp. 273-290. ISSN 0042-6822

Srivastava, Indresh K and Kan, Elaine and Sun, Yide and Sharma, Victoria A and Cisto, Jimna and Burke, Brian and Lian, Ying and Hilt, Susan and Biron, Zohar and Hartog, Karin and Stamatatos, Leonidas and Diaz-Avalos, Ruben and Cheng, R Holland and Ulmer, Jeffrey and Barnett, Susan W (2008) Comparative evaluation of trimeric envelope glycoproteins derived from subtype C and B HIV-1 R5 isolates. Virology, 372 (2). pp. 273-290. ISSN 0042-6822

Stansfeld, Phillip J and Grottesi, Alessandro and Sands, Zara A and Sansom, Mark S P and Gedeck, Peter and Gosling, Martin and Cox, Brian and Stanfield, Peter R and Mitcheson, John S and Sutcliffe, Michael J (2008) Insight into the mechanism of inactivation and pH sensitivity in potassium channels from molecular dynamics simulations. Biochemistry, 47 (28). pp. 7414-7422. ISSN 1520-4995

Stauffer, Frederic and Maira, Sauveur-Michel and Furet, Pascal and Garcia-Echeverria, Carlos (2008) Imidazo[4,5-c]quinolines as inhibitors of the PI3K/PKB-pathway. Bioorganic & Medicinal Chemistry Letters, 18 (3). pp. 1027-1030. ISSN 1464-3405

Stauffer, Frederic and Maira, Sauveur-Michel and Furet, Pascal and Garcia-Echeverria, Carlos (2008) Imidazo[4,5-c]quinolines as inhibitors of the PI3K/PKB-pathway. Bioorganic & Medicinal Chemistry Letters, 18 (3). pp. 1027-1030. ISSN 0960-894X

Stauffer, Frederic and Maira, Sauveur-Michel and Furet, Pascal and García-Echeverría, Carlos (2008) Imidazo[4,5-c]quinolines as inhibitors of the PI3K/PKB-pathway. Bioorganic & Medicinal Chemistry Letters, 18 (3). pp. 1027-3100. ISSN 1464-3405

Stickings, Paul and Peyre, Marisa and Coombes, Laura and Muller, Sylviane and Rappuoli, Rino and Del Giudice, Giuseppe and Partidos, Charalambos D and Sesardic, Dorothea (2008) Transcutaneous immunization with cross-reacting material CRM(197) of diphtheria toxin boosts functional antibody levels in mice primed parenterally with adsorbed diphtheria toxoid vaccine. Infection and Immunity, 76 (4). pp. 1766-1773. ISSN 1098-5522

Stickings, Paul and Peyre, Marisa and Coombes, Laura and Muller, Sylviane and Rappuoli, Rino and Del Giudice, Giuseppe and Partidos, Charalambos D and Sesardic, Dorothea (2008) Transcutaneous immunization with cross-reacting material CRM(197) of diphtheria toxin boosts functional antibody levels in mice primed parenterally with adsorbed diphtheria toxoid vaccine. Infection and immunity, 76 (4). pp. 1766-1773. ISSN 1098-5522

Stringer, Rowan and Nicklin, Paul and Houston, J B (2008) Reliability of human cryopreserved hepatocytes and liver microsomes as in vitro systems to predict metabolic clearance. Xenobiotica, 38 (10). pp. 1313-1329. ISSN 1366-5928

Sullivan, David and Martin, Eric (2008) Exploiting structure-activity relationships in docking. Journal of Chemical Information and Modeling, 48 (4). pp. 817-830. ISSN 1549-9596

Sullivan-Brown, Jessica and Schottenfeld, Jodi and Okabe, Noriko and Hostetter, Christine L and Serluca-Aegerter, Fabrizio and Thiberge, Stephan Y and Burdine, Rebecca D (2008) Zebrafish mutations affecting cilia motility share similar cystic phenotypes and suggest a mechanism of cyst formation that differs from pkd2 morphants. Developmental Biology, 314 (2). pp. 261-275. ISSN 1095-564X

Sullivan-Brown, Jessica and Schottenfeld, Jodi and Okabe, Noriko and Hostetter, Christine L and Serluca-Aegerter, Fabrizio and Thiberge, Stephan Y and Burdine, Rebecca D (2008) Zebrafish mutations affecting cilia motility share similar cystic phenotypes and suggest a mechanism of cyst formation that differs from pkd2 morphants. Developmental Biology, 314 (2). pp. 261-275. ISSN 1095-564X

Sumby, Paul and Zhang, Shizhen and Whitney, Adeline R and Falugi, Fabiana and Grandi, Guido and Graviss, Edward A and Deleo, Frank R and Musser, James M (2008) A chemokine-degrading extracellular protease made by group A Streptococcus alters pathogenesis by enhancing evasion of the innate immune response. Infection and immunity, 76 (3). pp. 978-985. ISSN 1098-5522

Séchaud, R and Dutreix, C and Balez, S and Pommier, F and Dumortier, T and Morisson, S and Brun, E (2008) Relative bioavailability of deferasirox tablets administered without dispersion and dispersed in various drinks. International journal of clinical pharmacology and therapeutics, 46 (2). pp. 102-108. ISSN 0946-1965

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Takahashi, Nozomi and de Jager, Victor C L and Glueck, Anton and Letzkus, Martin and Hartmann, Nicole and Staedtler, Frank and Ribeiro-Dias, Fatima and Heuvelmans-Jacobs, Marleen and van den Berg, Wim B and Joosten, Leo A B (2008) The molecular signature of oxidative metabolism and the mode of macrophage activation determine the shift from acute to chronic disease in experimental arthritis: critical role of interleukin-12p40. Arthritis and Rheumatism, 58 (11). pp. 3471-3484. ISSN 0004-3591

Tanner, Lukas and Schreiber, Mark and Low, Jenny and Ong, Adrian and Tolfvenstam, Thomas and Lai, Yee Ling and Ng, Lee Ching and Leo, Yee Sin and Thi Puong, Le and Vasudevan, Subhash and Simmons, Cameron P and Hibberd, Martin L and Ooi, Eng Eong (2008) Decision tree algorithms predict the diagnosis and outcome of dengue Fever in the early phase of illness. PLoS Neglected Tropical Diseases, 2 (3). e196. ISSN 1935-2735

Telford, John L (2008) Bacterial genome variability and its impact on vaccine design. Cell host & Microbe, 3 (6). pp. 408-416. ISSN 1934-6069

Tengvall, Sara and O'Hagan, Derek and Harandi, Ali M (2008) Rectal immunization generates protective immunity in the female genital tract against herpes simplex virus type 2 infection: relative importance of myeloid differentiation factor 88. Antiviral Research, 78 (3). pp. 202-214. ISSN 0166-3542

Teno, Naoki and Irie, Osamu and Miyake, Takahiro and Gohda, Keigo and Horiuchi, Miyuki and Tada, Sachiyo and Nonomura, Kazuhiko and Kometani, Motohiko and Iwasaki, Genji and Betschart, Claudia (2008) New chemotypes for cathepsin K inhibitors. Bioorganic & Medicinal Chemistry Letters, 18 (8). pp. 2599-2603. ISSN 1464-3405

Thoma, Gebhard and Beerli, Christian and Bigaud, Marc and Bruns, Christian and Cooke, Nigel Graham and Streiff, Markus and Zerwes, Hans-Guenter (2008) Reduced cardiac side-effect potential by introduction of polar groups: discovery of NIBR-1282, an orally bioavailable CCR5 antagonist which is active in vivo. Bioorganic & Medicinal Chemistry letters, 18 (6). pp. 2000-2005. ISSN 1464-3405

Thoma, Gebhard and Streiff, Markus and Kovarik, Jiri and Glickman, Fraser and Wagner, Beatrix and Beerli, Christian and Zerwes, Hans-Guenter (2008) Orally bioavailable isothioureas block function of the chemokine receptor CXCR4 in vitro and in vivo. Journal of Medicinal Chemistry, 51 (24). pp. 7915-7920. ISSN 1520-4804

Thomas, Matthew and Owen, Charles (2008) Inhibition of PI-3 kinase for treating respiratory disease: good idea or bad idea? Current Opinion in Pharmacology, 8 (3). pp. 267-274. ISSN 1471-4892

Tiao, Jim Yu-Hsiang and Bradaia, Amyaouch and Biermann, Barbara and Kaupmann, Klemens and Metz, Michaela and Haller, Corinne and Rolink, Antonius G and Pless, Elin and Barlow, Paul N and Gassmann, Martin and Bettler, Bernhard (2008) The sushi domains of secreted GABA(B1) isoforms selectively impair GABA(B) heteroreceptor function. The Journal of Biological Chemistry, 283 (45). pp. 31005-31011. ISSN 0021-9258

Titz, Alexander and Patton, John and Alker, Andre M and Porro, Michele and Schwardt, Oliver Roland and Hennig, Michael and Francotte, Eric and Magnani, John L. and Ernst, Beat (2008) Is adamantane a suitable substituent to pre-organize the acid orientation in E-selectin antagonists? Bioorganic & Medicinal Chemistry, 16 (2). pp. 1046-1056. ISSN 1464-3391

Titz, Alexander and Patton, John and Alker, André M and Porro, Michele and Schwardt, Oliver and Hennig, Michael and Francotte, Eric and Magnani, John and Ernst, Beat (2008) Is adamantane a suitable substituent to pre-organize the acid orientation in E-selectin antagonists? Bioorganic & Medicinal Chemistry, 16 (2). pp. 1046-1056. ISSN 1464-3391

Troxler, Thomas J. and Enz, Albert and Hoyer, Daniel and Langenegger, Daniel and Neumann, Peter and Pfaeffli, Paul and Schoeffter, Philippe and Hurth, Konstanze (2008) Ergoline derivatives as highly potent and selective antagonists at the somatostatin sst 1 receptor. Bioorganic & Medicinal Chemistry Letters, 18 (3). pp. 979-982. ISSN 1464-3405

Troxler, Thomas J. and Enz, Albert and Hoyer, Daniel and Langenegger, Daniel and Neumann, Peter and Pfaeffli, Paul and Schoeffter, Philippe and Hurth, Konstanze (2008) Ergoline derivatives as highly potent and selective antagonists at the somatostatin sst 1 receptor. Bioorganic & Medicinal Chemistry Letters, 18 (3). pp. 979-982. ISSN 1464-3405

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Umareddy, Indira and Tang, Kin Fai and Vasudevan, Subhash and Devi, Shamala and Hibberd, Martin L and Gu, Feng (2008) Dengue virus regulates type I interferon signalling in a strain-dependent manner in human cell lines. The Journal of General Virology, 89 (Pt 12). pp. 3052-3062. ISSN 0022-1317

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Vajpai, Navratna and Strauss, Andre and Fendrich, Gabriele and Jacob, Sandra and Manley, Paul W. and Grzesiek, Stephan and Jahnke, Wolfgang (2008) Solution conformations and dynamics of ABL kinase-inhibitor complexes determined by NMR substantiate the different binding modes of imatinib/nilotinib and dasatinib. The Journal of biological chemistry, 283 (26). pp. 18292-18302. ISSN 0021-9258

Van Dijck, Annemie and Vloeberghs, Ellen and Van Dam, Debby and Staufenbiel, Matthias and De Deyn, Peter Paul (2008) Evaluation of the APP23-model for Alzheimer's disease in the odour paired-associate test for hippocampus-dependent memory. Behavioural Brain Research, 190 (1). pp. 147-151. ISSN 0166-4328

Van Dijck, Annemie and Vloeberghs, Ellen and Van Dam, Debby and Staufenbiel, Matthias and De Deyn, Peter Paul (2008) Evaluation of the APP23-model for Alzheimer's disease in the odour paired-associate test for hippocampus-dependent memory. Behavioural Brain Research, 190 (1). pp. 147-151. ISSN 0166-4328

Van Eis, Maurice and BICKELHAUPT, M and VANLOON, S and LUTZ, M and SPEK, A and DEWOLF, W and VAN ZEIST, W and BICKELHAUPT, F (2008) Tricarbonylchromium complexes of [5]- and [6]metacyclophane: an experimental and theoretical study. Tetrahedron, 64 (51). pp. 11641-11646. ISSN 0040-4020

Vanoni, Omar and Paganetti, Paolo and Molinari, Maurizio (2008) Consequences of individual N-glycan deletions and of proteasomal inhibition on secretion of active BACE. Molecular Biology of the Cell, 19 (10). pp. 4086-4098. ISSN 1939-4586

Verheul, Henk M W and Salumbides, Brenda and Van Erp, Karen and Hammers, Hans and Qian, David Z and Sanni, Tolib and Atadja, Peter and Pili, Roberto (2008) Combination strategy targeting the hypoxia inducible factor-1 alpha with mammalian target of rapamycin and histone deacetylase inhibitors. Clinical Cancer Research: an official journal of the American Association for Cancer Research, 14 (11). pp. 3589-3597. ISSN 1078-0432

Vlkolinsky, Roman and Krucker, Thomas and Nelson, Gregory A and Obenaus, Andre (2008) (56)Fe-particle radiation reduces neuronal output and attenuates lipopolysaccharide-induced inhibition of long-term potentiation in the mouse hippocampus. Radiation Research, 169 (5). pp. 523-530. ISSN 0033-7587

van Meeteren, Laurens A and Brinkmann, Volker and Saulnier-Blache, Jean Sebastien and Lynch, Kevin and Moolenaar, Wouter H (2008) Anticancer activity of FTY720: phosphorylated FTY720 inhibits autotaxin, a metastasis-enhancing and angiogenic lysophospholipase D. Cancer Letters, 266 (2). pp. 203-208. ISSN 0304-3835

W

Wang, Biao and Goode, Jason and Best, Jennifer and Meltzer, Jodi and Schilman, Pablo E and Chen, Jian and Garza, Dan and Thomas, John B and Montminy, Marc (2008) The insulin-regulated CREB coactivator TORC promotes stress resistance in Drosophila. Cell Metabolism, 7 (5). pp. 434-444. ISSN 1932-7420

Wang, Zhi Gang and Fukazawa, Takuya and Nishikawa, Toshio and Watanabe, Nobuyuki and Sakurama, Kazufumi and Motoki, Takayuki and Takaoka, Munenori and Hatakeyama, Shinji and Omori, Osamu and Ohara, Toshiaki and Tanabe, Shunsuke and Fujiwara, Yasuhiro and Shirakawa, Yasuhiro and Yamatsuji, Tomoki and Tanaka, Noriaki and Naomoto, Yoshio (2008) TAE226, a dual inhibitor for FAK and IGF-IR, has inhibitory effects on mTOR signaling in esophageal cancer cells. Oncology Reports, 20 (6). pp. 1473-1477. ISSN 1021-335X

Wang, Ling and Montano, Monty and Rarick, Matt and Sebastiani, Paola (2008) Conditional clustering of temporal expression profiles. BMC Bioinformatics, 9. p. 147. ISSN 1471-2105

Wannier-Morino, P and Schmidlin, E and Freund, P and Belhaj-Saif, A and Bloch, J and Mir, Anis Khusro and Schwab, M E and Rouiller, E M and Wannier, T (2008) Fate of rubrospinal neurons after unilateral section of the cervical spinal cord in adult macaque monkeys: effects of an antibody treatment neutralizing Nogo-A. Brain Research, 1217. pp. 96-109. ISSN 0006-8993

Watanabe, Nobuyuki and Takaoka, Munenori and Sakurama, Kazufumi and Tomono, Yasuko and Hatakeyama, Shinji and Ohmori, Osamu and Motoki, Takayuki and Shirakawa, Yasuhiro and Yamatsuji, Tomoki and Haisa, Minoru and Matsuoka, Junji and Beer, David G and Nagatsuka, Hitoshi and Tanaka, Noriaki and Naomoto, Yoshio (2008) Dual tyrosine kinase inhibitor for focal adhesion kinase and insulin-like growth factor-I receptor exhibits anticancer effect in esophageal adenocarcinoma in vitro and in vivo. Clinical Cancer Research : an official journal of the American Association for Cancer Research, 14 (14). pp. 4631-4639. ISSN 1078-0432

Wee, Susan and Lengauer, Christoph and Wiederschain, Dmitri (2008) Class IA phosphoinositide 3-kinase isoforms and human tumorigenesis: implications for cancer drug discovery and development. Current Opinion in Oncology, 20 (1). pp. 77-82. ISSN 1040-8746

Wee, Susan and Wiederschain, Dmitri and Maira, Sauveur-Michel and Loo, Alice and Miller, Christine and De Beaumont, Rosalie and Stegmeier, Frank and Yao, Yung-Mae and Lengauer, Christoph (2008) PTEN-deficient cancers depend on PIK3CB. Proceedings of the National Academy of Sciences of the United States of America, 105 (35). pp. 13057-13062. ISSN 0027-8424

Weiss, Andreas and Klein, Corinna and Woodman, Ben and Sathasivam, Kirupa and Bibel, Miriam and Regulier, Etienne and Bates, Gillian and Paganetti, Paolo (2008) Sensitive biochemical aggregate detection reveals aggregation onset before symptom development in cellular and murine models of Huntington's disease. Journal of Neurochemistry, 104 (3). pp. 846-858. ISSN 1471-4159

Weiss, Markus and Fresneau, Marcel and Moenius, Thomas and Stuetz, Anton and Billich, Andreas (2008) Binding of pimecrolimus and tacrolimus to skin and plasma proteins: implications for systemic exposure after topical application. Drug metabolism and disposition: the biological fate of chemicals, 36 (9). pp. 1812-1818. ISSN 1521-009X

Weiss, Markus and Pfaar, Ulrike and Schweitzer, Alain and Wiegand, Hansjörg and Skerjanec, Andrej and Schran, Horst (2008) Biodistribution and plasma protein binding of zoledronic acid. Drug metabolism and disposition: the biological fate of chemicals, 36 (10). pp. 2043-2049. ISSN 1521-009X

Wendorf, Janet and Chesko, James and Kazzaz, Jina and Ugozzoli, Mildred and Vajdy, Michael and O'Hagan, Derek and Singh, Manmohan (2008) A comparison of anionic nanoparticles and microparticles as vaccine delivery systems. Human Vaccines, 4 (1). pp. 44-49. ISSN 1554-8619

Wetzel, S and Renner, S and Nören-Müller, A and Schuffenhauer, Ansgar and Ertl, Peter and Waldmann, Herbert (2008) BIOS: Similarity-based design of natural product derived compound collections. Chemistry Central Journal, 2 (Suppl ). P48. ISSN 1752-153X

Wu, Chunlei and Delano, David and Mitro, Nico and Su, Stephen and Janes, Jeff and Mcclurg, Phillip and Batalov, Sergei and Welch, Genevieve and Zhang, Jie and Orth, Anthony and Walker, John and Glynne, Richard and Cooke, Michael and Takahashi, Joseph and Shimomura, Kazuhiro and Kohsaka, Akira and Bass, Joseph and Saez, Enrique and Wiltshire, Timothy and Su, Andrew (2008) Gene set enrichment in eQTL data identifies novel annotations and pathway regulators. PLoS Genetics, 4 (5). e1000070. ISSN 1553-7404

Y

Yang, Lin and Clarke, Michelle J and Carlson, Brett L and Mladek, Ann C and Schroeder, Mark A and Decker, Paul and Wu, Wenting and Kitange, Gaspar J and Grogan, Patrick T and Goble, Jennie M and Uhm, Joon and Galanis, Evanthia and Giannini, Caterina and Lane, Heidi and James, C David and Sarkaria, Jann N (2008) PTEN loss does not predict for response to RAD001 (Everolimus) in a glioblastoma orthotopic xenograft test panel. Clinical Cancer Research: an official journal of the American Association for Cancer Research, 14 (12). pp. 3993-4001. ISSN 1078-0432

Yang, Lin and Clarke, Michelle J and Carlson, Brett L and Mladek, Ann C and Schroeder, Markus and Decker, Paul and Wu, Wenting and Kitange, Gaspar J and Grogan, Patrick T and Goble, Jennie M and Uhm, Joon and Galanis, Evanthia and Giannini, Caterina and Lane, Heidi and James, David and Sarkaria, Jann N (2008) PTEN loss does not predict for response to RAD001 (Everolimus) in a glioblastoma orthotopic xenograft test panel. Clinical Cancer Research : an official journal of the American Association for Cancer Research, 14 (12). pp. 3993-4001. ISSN 1078-0432

Yang, Yonghua and Rao, Rehka and Shen, Jie and Tang, Yun and Fiskus, Warren and Nechtman, John and Atadja, Peter and Bhalla, Kapil (2008) Role of acetylation and extracellular location of heat shock protein 90alpha in tumor cell invasion. Cancer Research, 68 (12). pp. 4833-4842. ISSN 1538-7445

You, Taek and Lee, Mi and Jenkins, Jeremy and Alzate, Oscar and Dean, Donald (2008) Blocking binding of Bacillus thuringiensis Cry1Aa to Bombyx mori cadherin receptor results in only a minor reduction of toxicity. BMC Biochemistry, 9 (1). p. 3. ISSN 1471-2091

Young, Daniel and Bender, Andreas and Hoyt, Jonathan and McWhinnie, Elizabeth and Chirn, Gung-Wei and Tao, Charles and Tallarico, John and Labow, Mark and Jenkins, Jeremy and Mitchison, Timothy and Feng, Yan (2008) Integrating high-content screening and ligand-target prediction to identify mechanism of action. Nature Chemical Biology, 4 (1). pp. 59-68. ISSN 1552-4469

Yu, Chunrong and Friday, Bret B and Yang, Lin and Atadja, Peter and Wigle, Dennis and Sarkaria, Jann and Adjei, Alex A (2008) Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells. Neuro-Oncology, 10 (3). pp. 309-319. ISSN 1522-8517

Yu, Chunrong and Friday, Bret B and Yang, Lin and Atadja, Peter and Wigle, Dennis and Sarkaria, Jann and Adjei, Alex A (2008) Mitochondrial Bax translocation partially mediates synergistic cytotoxicity between histone deacetylase inhibitors and proteasome inhibitors in glioma cells. Neuro-Oncology, 10 (3). pp. 309-319. ISSN 1522-8517

Z

Zeggini, Eleftheria and Scott, Laura J and Saxena, Richa and Voight, Benjamin F and Marchini, Jonathan L and Hu, Tianle and de Bakker, Paul I W and Abecasis, Gonçalo R and Almgren, Peter and Andersen, Gitte and Ardlie, Kristin and Boström, Kristina Bengtsson and Bergman, Richard N and Bonnycastle, Lori L and Borch-Johnsen, Knut and Burtt, Noël P and Chen, Hong and Chines, Peter S and Daly, Mark J and Deodhar, Parimal and Ding, Chia-Jen and Doney, Alex S F and Duren, William L and Elliott, Katherine S and Erdos, Michael R and Frayling, Timothy M and Freathy, Rachel M and Gianniny, Lauren and Grallert, Harald and Grarup, Niels and Groves, Christopher J and Guiducci, Candace and Hansen, Torben and Herder, Christian and Hitman, Graham A and Hughes, Thomas and Isomaa, Bo and Jackson, Anne U and Jorgensen, Torben and Kong, Augustine and Kubalanza, Kari and Kuruvilla, Finny G and Kuusisto, Johanna and Langenberg, Claudia and Lango, Hana and Lauritzen, Torsten and Li, Yun and Lindgren, Cecilia M and Lyssenko, Valeriya and Marvelle, Amanda F and Meisinger, Christa and Midthjell, Kristian and Mohlke, Karen L and Morken, Mario A and Morris, Andrew D and Narisu, Narisu and Nilsson, Peter and Owen, Katharine R and Palmer, Colin N A and Payne, Felicity and Perry, John R B and Pettersen, Elin and Platou, Carl and Prokopenko, Inga and Qi, Lu and Qin, Li and Rayner, Nigel W and Rees, Matthew and Roix, Jeffrey and Sandbaek, Anelli and Shields, Beverley and Sjögren, Marketa and Steinthorsdottir, Valgerdur and Stringham, Heather M and Swift, Amy J and Thorleifsson, Gudmar and Thorsteinsdottir, Unnur and Timpson, Nicholas J and Tuomi, Tiinamaija and Tuomilehto, Jaakko and Walker, Mark and Watanabe, Richard M and Weedon, Michael N and Willer, Cristen J and Illig, Thomas and Hveem, Kristian and Hu, Frank B and Laakso, Markku and Stefansson, Kari and Pedersen, Oluf and Wareham, Nicholas J and Barroso, Inês and Hattersley, Andrew T and Collins, Francis S and Groop, Leif and McCarthy, Mark I and Boehnke, Michael and Altshuler, David (2008) Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes. Nature Genetics, 40 (5). pp. 638-645. ISSN 1546-1718

Zhang, Min and Fu, Wuxia and Prabhu, Sharmila and Moore, James C and Ko, Je and Kim, Jung Woo and Druker, Brian J and Trapp, Valerie and Fruehauf, John and Gram, Hermann and Fan, Hung Y and Ong, S Tiong (2008) Inhibition of polysome assembly enhances imatinib activity against chronic myelogenous leukemia and overcomes imatinib resistance. Molecular and Cellular Biology, 28 (20). pp. 6496-6509. ISSN 1098-5549

Zhou, Liping and Skolnik, Suzanne and Yang, Linhong and Wang, Jianling (2008) Solubility-driven successful drug discovery. Solubility-driven successful drug discovery, Apr/Ma. pp. 20-22.

Zhou, Liping and Wang, Jianling (2008) Physio-chemical Characterization in Drug Discovery. Physio-chemical Characterization in Drug Discovery, 4. pp. 12-18.

Ziermann, Rainer and Sanchez-Guerrero, Sergio Arturo (2008) PROCLEIX West Nile virus assay based on transcription-mediated amplification. Expert Review of Molecular Diagnostics, 8 (3). pp. 239-245. ISSN 1744-8352

This list was generated on Mon Dec 9 05:21:10 2019 UTC.

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