Efficacy and safety of artemether-lumefantrine dispersible tablets compared with crushed commercial tablets in African infants and children with uncomplicated malaria: a randomised, single-blind, multicentre trial.
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Abdulla, Salim, Sagara, Issaka, Borrmann, Steffen, D'Alessandro, Umberto, González, Raquel, Hamel, Mary, Ogutu, Bernhards, Mårtensson, Andreas, Lyimo, John, Maiga, Hamma, Sasi, Philip, Nahum, Alain, Bassat, Quique, Juma, Elizabeth, Otieno, Lucas, Björkman, Anders, Beck, Hans Peter, Andriano, Kim, Cousin, Marc, Lefevre, Gilbert, Ubben, David and Premji, Zulfikarali (2008) Efficacy and safety of artemether-lumefantrine dispersible tablets compared with crushed commercial tablets in African infants and children with uncomplicated malaria: a randomised, single-blind, multicentre trial. Lancet, 372 (9652). pp. 1819-1827. ISSN 1474-547X
Abstract
Combination treatments, preferably containing an artemisinin derivative, are recommended to improve efficacy and prevent Plasmodium falciparum drug resistance. Our aim was to show non-inferiority of a new dispersible formulation of artemether-lumefantrine to the conventional crushed tablet in the treatment of young children with uncomplicated malaria.
| Item Type: | Article |
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| Date Deposited: | 28 Jan 2012 00:45 |
| Last Modified: | 01 Feb 2013 00:47 |
| URI: | https://oak.novartis.com/id/eprint/5095 |