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Number of items: 233.

A

Accart Gris, Nathalie and Genoud, Christel (2019) Un premier pas vers l’étude du collagène du cartilage articulaire en microscopie électronique. Revue Française d'Histotechnologie, 31 (1). pp. 85-92. ISSN 0997-6434

Adams, Christopher and Stacy, Rebecca and Rangaswamy, Nalini and Bigelow, Chad and Grosskreutz, Cyndy and Prasanna, Ganesh (2019) Glaucoma - Next Generation Therapeutics: Impossible to Possible. Pharmaceutical Research, 36 (2). ISSN 1573904X

Aeffner, Famke and Zarella, Mark and Buchbinder, Nathan and Bui, Marilyn and Goodman, Matthew and Hartman, Douglas and Lujan, Giovanni and Molani, Mariam and Parwani, Anil and Tunstall, kate and Turner, Oliver and Vemuri, Venkata and Yuil-Valdes, Ana and Bowman, Douglas (2019) Introduction to Digital Image Analysis in Whole-Slide Imaging: A White Paper from the Digital Pathology Association. Journal of Pathology Informatics, 10 (9). pp. 1-17.

Aeschlimann, Samuel and Graf, Christian and Mayilo, Dmytro and Munschy, Helene and Urda, Lorena and Kappes, Nora and Simonis, Marieke and Splinter, Erik and van Min, Max and Laux, Holger (2019) Shortened abstract for Enhanced CHO clone screening using Next-Generation Sequencing and Targeted Locus Amplification publication. Enhanced CHO clone screening: Applying Targeted Locus Amplification and Next-Generation Sequencing technologies during cell line development.

Aguilar-de-Leyva, Ángela and Campiñez, Maria Dolores and Jost, Flavia and Gavira, Miguel and Caraballo, Isidoro (2019) Study of the critical points in combined matrix tablets containing both inert and swelling excipients. Journal of Drug Delivery Science and Technology, 52. pp. 885-894. ISSN 17732247

Aho, Erin R and Wang, Jing and Gogliotti, Rocco D and Howard, Gregory C and Phan, Jason and Acharya, Pankaj and Macdonald, Jonathan D and Cheng, Ken and Lorey, Shelly L and Lu, Bin and Wenzel, Sabine and Foshage, Audra M and Alvarado, Joseph and Wang, Feng and Shaw, J Grace and Zhao, Bin and Weissmiller, April M and Thomas, Lance R and Vakoc, Christopher R and Hall, Matthew D and Hiebert, Scott W and Liu, Qi and Stauffer, Shaun R and Fesik, Stephen W and Tansey, William P (2019) Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity. Cell reports, 26 (11). 2916-2928.e13. ISSN 2211-1247

Alexander, Schuhmacher and Oliver, Gassmann and Michael, Kuss and Hinder, Markus (2019) The Art of Virtualizing Pharma R&D. Drug Discovery Today. pp. 1-2. ISSN 18785832

Altshuler, Bob (2019) Research summary for postdoc program mentor profile. NIBR Postdoc Program.

Ando, Yuichi and Iwasa, Satoru and Takahashi, Shunji and Saka, Hideo and KAKIZUME, TOMOYUKI and NATSUME, KAZUTO and NOUMI, NAOKO and Quadt, Cornelia and Yamada, Yasuhide (2019) Phase I study of alpelisib (BYL719), an α-specific PI3K inhibitor, in Japanese patients with advanced solid tumors. Cancer Science. ISSN 13497006

Arias, HR and Jin, X-T and Peng, C and Feuerbach, Dominik and Ortells, MO and Elgoyhen, AB and Drenan, RM (2019) Selectivity of (±)-citalopram at nicotinic acetylcholine receptors and different inhibitory mechanisms between habenular α3β4* and α9α10 subtypes. Neurochemistry international.

Arias, Hugo R and Ortells, Marcelo O and Feuerbach, Dominik and Burgos, Viviana and Paz, Cristian (2019) Alkaloids purified from the Aristotelia chilensis tree inhibit the human α3β4 nicotinic acetylcholine receptor with higher potency compared to human α4β2 and α7 subtypes. Journal of natural products.

Arista, Luca and Ullrich, Thomas and Riela, Serena and Massaro, Marina and Buscemi, Gabriella and Biddeci, Giuseppa and Cavallaro, Giuseppe and D'Anna, Francesca and Di Blasi, Francesco and Ferrante, Angelo and Lazzara, Giuseppe and Rizzo, Carla and Spinelli, Gaetano (2019) Multifunctional carrier based on halloysite/laponite hybrid hydrogel for kartogenin delivery. ACS Medicinal Chemistry Letters, 2019 (10). pp. 419-424. ISSN 1948-58751948-5875

Arora, Rishi and Nimonkar, Amitabh and Baird, Daniel and Wang, Chunhua and Chiu, Chun-Hao and Horton, Patricia and Hanrahan, Susan and Cubbon, Rose and Weldon, Stephen and Tschantz, Bill and Mueller, Sascha and Brunner, Reto and Lehr, Philipp and Meier, Peter and Ottl, Johannes and Voznesensky, Andrei and Pandey, Pramod and Smith, Thomas and Stojanovic, Aleksandar and Flyer, Alec and Benson, Timothy and Romanowski, Michael and Trauger, John (2019) Structure of lipoprotein lipase in complex with GPIHBP1. Proceedings of the National Academy of Sciences of the United States of America, 116 (21). pp. 10360-10365. ISSN 10916490

Arora, Rishi and Nimonkar, Amitabh V and Baird, Daniel and Wang, Chunhua and Chiu, Chun-Hao and Horton, Patricia A and Hanrahan, Susan and Cubbon, Rose and Weldon, Stephen and Tschantz, William R and Mueller, Sascha and Brunner, Reto and Lehr, Philipp and Meier, Peter and Ottl, Johannes and Voznesensky, Andrei and Pandey, Pramod and Smith, Thomas M and Stojanovic, Aleksandar and Flyer, Alec and Benson, Timothy E and Romanowski, Michael J and Trauger, John W (2019) Structure of lipoprotein lipase in complex with GPIHBP1. Proceedings of the National Academy of Sciences of the United States of America. ISSN 1091-6490

Arora, Rishi and Nimonkar, Amitabh V and Baird, Daniel and Wang, Chunhua and Chiu, Chun-Hao and Horton, Patricia A and Hanrahan, Susan and Cubbon, Rose and Weldon, Stephen and Tschantz, William R and Mueller, Sascha and Brunner, Reto and Lehr, Philipp and Meier, Peter and Ottl, Johannes and Voznesensky, Andrei and Pandey, Pramod and Smith, Thomas M and Stojanovic, Aleksandar and Flyer, Alec and Benson, Timothy E and Romanowski, Michael J and Trauger, John W (2019) Structure of lipoprotein lipase in complex with GPIHBP1. Proceedings of the National Academy of Sciences of the United States of America, 116 (21). pp. 10360-10365. ISSN 1091-6490

Artim, Stephen C and Sheh, Alexander and Burns, Monika A and Fox, James G (2019) Evaluating rectal swab collection method for gut microbiome analysis in the common marmoset (Callithrix jacchus). PloS one, 14 (11). e0224950. ISSN 1932-6203

Auberson, Yves (2019) An Element of Community: EFMC, the European Federation for Medicinal Chemistry. Chimia..

B

Babrak, Lmar M. and Menetski, Joseph and Rebhan, Michael and Nisato, Giovanni and Zinggeler, Marc and Brasier, Noe and Baerenfaller, Katja and Brenzikofer, Thomas and Baltzer, Laurenz and Vogler, Christian and Gschwind, Leo and Schneider, Cornelia and Streiff, Fabian and Groenen, Peter M.A. and Miho, Enkelejda (2019) Traditional and digital biomarkers - two worlds apart? Digital Biomarkers, 3 (2). pp. 92-102. ISSN 2504-110X

Baenziger, Markus and Eswaran, Sumesh and Kanasithan, Gopu and Jiang, Yifan (2019) Selective ortho -Metalation of a Fluoroarene with Knochel-Hauser Base and Reactions with Various Electrophiles. Synthesis (Germany), 51 (7). pp. 1649-1654. ISSN 1437210X

Baenziger, Markus and Pachinger, Werner and Stauffer, Frederic and Zaugg, Werner (2019) Development of the synthesis of BEZ235 on ton scale. Organic Process Research & Development, 23 (9). pp. 1908-1917. ISSN 1083-61601520-586X

Bagdanoff, Jeffrey and Acker, Michael and Chan, Ho Man and Dore, Michael and Firestone, Brant and Fodor, Michelle and Garcia Fortanet, Jorge and Hentemann, Martin and Kato, Mitsunori and Koenig, Robert and La Bonte, Laura and Liu, Shumei and Chen, Zhuoliang and Chen, Ying-Nan and Mohseni, Mori and Ntaganda, Rukundo and Sarver, Patrick and Smith, Troy and Sendzik, Martin and Stams, Travis and Spence, Stan and Towler, Christopher and Wang, Hongyun and Wang, Ping and Williams, Sarah (2019) Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors. Journal of Medicinal Chemistry, 62 (4). pp. 1781-1792. ISSN 15204804

Bassilana, Frederic and Nash, Mark and Ludwig, Marie-Gabrielle (2019) Adhesion G protein-coupled receptors: opportunities for drug discovery. Nature reviews drug discovery.

Beck, Katharina R. and Kanagaratnam, Sharavan and Kratschmar, Denise V. and Birk, Julia and Yamaguchi, Hideaki and Sailer, Andreas and Seuwen, Klaus and Odermatt, Alex (2019) Enzymatic interconversion of the oxysterols 7β,25-dihydroxycholesterol and 7-keto,25-hydroxycholesterol by 11β-hydroxysteroid dehydrogenase type 1 and 2. Journal of steroid biochemistry and molecular biology, 190. pp. 19-28. ISSN 1879-1220

Bednarczyk, Dallas and Sanghvi, Menaka (2019) The impact of assay recovery on the apparent permeability, a function of lysosomal trapping. Xenobiotica; the fate of foreign compounds in biological systems. pp. 1-22. ISSN 13665928

Bernink, Jochem H and Ohne, Yoichiro and Teunissen, Marcel BM and wang, Jingya and wu, Jincheng and krabbendam, lisette and Guntermann, Christine and volckmann, richard and koster, jan and van Tol, sophie and ramirez, ivan and shrestha, yashaswi and de rie, menno a and spits, hergen and ros, xavier romero and humbles, alison a (2019) c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies. Nature immunology. ISSN 1529-2916

Berrien-Elliott, Melissa M. and Sun, Yaping and Neal, Carly and Ireland, Aaron and Trissal, Maria C. and Sullivan, Ryan and Wagner, Julia A. and Leong, Jeffrey W. and Wong, Pamela and Mah-Som, Annelise Y. and Wong, Terrence N. and Schappe, Timothy and Keppel, Catherine R. and Cortez, Victor S. and Stamatiades, Efstathios G. and Li, Ming O. and Colonna, Marco and Link, Daniel C. and French, Anthony R. and Cooper, Megan A. and Wang, Wei-Le and Boldin, Mark P. and Reddy, Pavan and Fehniger, Todd A. (2019) MicroRNA-142 Is Critical for the Homeostasis and Function of Type 1 Innate Lymphoid Cells. Immunity. ISSN 10747613

Bhhatarai, Barun and Walters, Patrick and Hop, Cornelis and Lanza, Guido and Ekins, Sean (2019) Opportunities and Challenges Using Artificial Intelligence (AI) in ADME/Tox. Nature materials., 18. pp. 418-422. ISSN 1476-1122

Bill, Anke and Yeboah, Fred and Kim, Tae-Eu and Dettmer, Ulf (2019) Dynamic behaviors of α-synuclein and tau in the cellular context: New mechanistic insights and therapeutic opportunities in neurodegeneration. Neurobiology of Disease, 132. ISSN 1095953X

Borsari, Chiara and Rageot, Denise and Dall’Asen, Alix and Bohnacker, Thomas and Melone, Anna and Sele, Alexander M. and Jackson, Eileen and Langlois, Jean-Baptiste and Beaufils, Florent and Hebeisen, Paul and Fabbro, Doriano and Hillmann, Petra and Wymann, Matthias P. (2019) A Conformational Restriction Strategy for the Identification of a Highly Selective Pyrimido-pyrrolo-oxazine mTOR Inhibitor. Journal of Medicinal Chemistry, 62 (18). pp. 8609-8630. ISSN 0022-2623

Briard, Emmanuelle and joshi, Aniket and Shanmukhappa, Shiva and Ilovich, Olav and Auberson, Yves (2019) [18F]PRIMATX, a New Positron Emission Tomography Tracer for Imaging of Autotaxin in Lung Tissue and Tumor‐Bearing Mice. ChemMedChem.

Brock, Ansgar and Venable, John and Steckler, Caitlin and Park, In Hee (2019) Interlaboratory Comparison of Hydrogen-Deuterium Exchange Mass Spectrometry Measurements of the Fab fragment of NISTmAb. Analytical chemistry. ISSN 0003-2700

Bruch, Richard and Baaske, Julia and Chatelle, Claire and Meirich, Mailin and Madlener, Sibylle and Weber, Wilfried and Dincer, Can and Urban, Gerald Anton (2019) CRISPR/Cas13a‐powered electrochemical microfluidic biosensor for nucleic acid amplification‐free miRNA diagnostics. Advanced Materials. p. 1905311. ISSN 0935-9648

Bruin, Gerardus and Hasselberg, Anke and Korolova, Irena and Milojevic, Julie and Calonder, Claudio and Soon, Rachel and Woessner, Ralph and Pariser, David and Boutouyrie-Dumont, Bruno (2019) Secukinumab treatment does not alter the pharmacokinetics of the CYP3A4 substrate midazolam in patients with moderate to severe psoriasis – results from an open label disease-drug-drug interaction study. Clinical pharmacology and therapeutics, Early (Early ).

Burns, Michael and Ott, Martin and Teasdale, Andrew and Stalford, Susanne and Antonucci, Vincent and Baumann, Jens-Christoph and Brown, Roland and Covey-Crump, Elisabeth and Elder, David and Elliott, Eric and Fennell, Jarred and Gallou, Fabrice and Ide, Nathan and Itoh, Tetsuji and Jordine, Guido and Kallemeyn, Jeffrey and Lauwers, Dick and Looker, Adam and Lovelle, Lucie and Molzahn, Robert and Schills, Didier and Schulte Oestrich, Rolf and Sluggett, Gregory and Stevenson, Neil and Talavera, Pere and Urquhart, Michael and Varie, David and Welch, Dennie (2019) A New Semi-Automated Computer-Based System for Assessing the Purge of Mutagenic Impurities. Organic process research & development.

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Cadena, Samuel and Choi, Sungshin and Saravia-Butler, Amanda and Shirazi-Fard, Yasaman and Leveson-Gower, Dennis and Stodieck, Louis and Beegle, Janet and Solis, Stephanie and Ronca, April and Globus, Ruth (2019) Behavior of mice aboard the International Space Station. Scientific reports, 9 (1). ISSN 20452322

Cadena, Samuel and Zhang, Yunyu and Lemire, Sophie and Kuss, Pia and Giorgetti, Elisa and Kneissel, Michaela and Glass, David and Stodieck, Louis (2019) Skeletal muscle in MuRF1 null mice is not spared in low-gravity conditions, indicating atrophy proceeds by unique mechanisms in space. Skeletal muscle in MuRF1 null mice is not spared in low-gravity conditions, indicating atrophy proceeds by unique mechanisms in space , 9 (1). p. 9397. ISSN 2045-2322

Camenisch, Gian P. (2019) DRUG-INDUCED LIVER INJURY PREDICTIONS: EXTENDED CLEARANCE MODEL AND ITS USE FOR PROPSPECTIVE TRANSPORTER- AND ENZYME-BASED HEPATIC CELL STRESS GRADING. International Journal of Pharmacy and Chemistry, 5 (2). pp. 15-19. ISSN 2575-5730

Carballido, Jose and Santamaria, Pere (2019) Taming autoimmunity: Translating antigen-specific approaches to induce immune tolerance. The Journal of Experimental Medicine. ISSN 0022-10071540-9538

Chapeau, Emilie and Mandon, Emeline and Romanet, Vincent and Ebel, Nicolas and Gill , Jason and Powajbo, Violetta and Andraos-Rey, Rita and Qian, Zhiyan and Kininis, Miltiadis and Zumstein-Mecker, Sabine and Ito, Moriko and Hynes, Nancy and Hofmann, Francesco and Tiedt, Ralph and Eshkind, Leonid and Bockamp, Ernesto and Kinzel, Bernd and Mueller, Matthias and Murakami, Masato and Baffert, Fabienne and Radimerski, Thomas (2019) A conditional inducible JAK2V617F transgenic mouse model reveals myeloproliferative disease that is reversible upon switching off transgene expression. PLoS ONE, 14 (10). ISSN 1932-6203

Chen, Kaiwen and Demarco, Benjamin and Shkarina, Kateryna and Boettcher, Andreas and Farady, Christopher and Heilig, Rosalie and Broz, Petr and Pelzcar, P (2019) Extrinsic and intrinsic apoptosis activate pannexin-1 to drive NLRP3 inflammasome assembly. EMBO Journal. ISSN 14602075

Chen, Lieyang and Cruz, Anthony and Ramsey, Steven and Dickson, Callum and Duca, Jose and Hornak, Viktor and Koes, David and Kurtzman, Tom (2019) Hidden bias in the DUD-E dataset leads to misleading performance of deep learning in structure-based virtual screening. PLoS ONE, 14 (8). ISSN 19326203

Christian, Alec H and Jia, Shang and Zhang, Patricia and Tena Meza, Arismel and Sigman, Matthew S and Chang, Christopher J and Toste, F Dean (2019) A Physical Organic Approach to Tuning Reagents for Selective and Stable Methionine Bioconjugation. Journal of the American Chemical Society JACS., 141 (32). pp. 12657-12662. ISSN 0002-78631520-5126

Clavaud, Matthieu and Lema-Martinez, Carmen and Roggo, Yves and Bigalke, Michael and Guillemain, Aurélie and Hubert, Philippe and Ziemons, Eric and Allmendinger, Andrea (2019) Near-infrared spectroscopy to determine residual moisture in freeze-dried products: model generation by statistical design of experiments. Journal of Pharmaceutical Sciences. ISSN 00223549

Cooner, Freda and Gamalo-Siebers, Margaret and Xia, Amy and Aijun, Gao and Ruan, Shiling and Tony, Jiang and Laura, Thompson (2019) Use of Alternative Designs and Data Sources for Pediatric Trials. Statistics in Biopharmaceutical Research. ISSN 19466315

Costa, Carlotta and Ly, Amy and Walmsley, Charlotte S. and Huynh, Tiffany and Healy, Christopher and Peterson, Rachel and Jakubik, Charles T. and Henderson, Laura E. and Ho, Jeffrey and Timotina, Daria and Sanidas, Ioannis and Veloso, Artur and Mino-Kenudson, Mari and Stone, James R. and Dyson, Nick and Benes, Cyril H. and Engelman, Jeffrey and Dejan, Juric (2019) PTEN loss mediates clinical cross-resistance to CDK4/6 and PI3Kα inhibitors in breast cancer. Cancer discovery. ISSN 21598290

Cryer, Alexander M and Chan, Cheuk and Eftychidou, Anastasia and Maksoudian, Christy and Mahesh, Mohan and Tetley, Teresa D and Spivey, Alan C and Thorley, Andrew J (2019) Tyrosine Kinase Inhibitor Gold Nanoconjugates for the Treatment of Non-Small Cell Lung Cancer. ACS applied materials & interfaces, 11 (18). pp. 16336-16346. ISSN 1944-8252

Cryer, Alexander M and Thorley, Andrew J (2019) Nanotechnology in the diagnosis and treatment of lung cancer. Pharmacology & therapeutics, 198. pp. 189-205. ISSN 1879-016X

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D'Alessandro, Pier Luca and Hollingworth, Greg and Vorherr, Thomas (2019) Real-Time Imaging and Quantification of Peptide Uptake in Vitro and in Vivo. ACS Chemical Biology, 14 (10). pp. 2197-2205. ISSN 15548937

D'Alessandro, Pier Luca and Hollingworth, Greg and Vorherr, Thomas (2019) Real-time imaging and quantification of peptide uptake in vitro and in vivo. ACS Chemical Biology. ISSN 1554-89291554-8937

Dalvit, Claudio and Vulpetti, Anna (2019) Ligand-Based Fluorine NMR Screening: Principles and Applications in Drug Discovery Projects. Journal of Medicinal Chemistry, 62. pp. 2218-2244. ISSN 15204804

Daniela, Mercatelli and Bolognesi, Paolo and Frassineti, Martina and Clarissa, Pisanò and Francesco, Longo and Shimshek, Derya and Michele, Morari (2019) Leucine-rich repeat kinase 2 (LRRK2) inhibitors differentially modulate glutamate release and Serine935 LRRK2 phosphorylation in striatal and cerebrocortical synaptosomes. Pharmacology Research & Perspectives, 7 (3). ISSN 2052-17072052-1707

Darpo, B and Benson, C and Dota, C and Jarugula, Venkateswar (2019) Evaluation of the Effect of 5 QT-Positive Drugs on the JTpeak Interval — An Analysis of ECGs From the IQ-CSRC Study. Journal of Clinical Pharmacology. ISSN 15524604

Diaz Verdugo, Carmen and Sun, Gerald and Fawcett, Caroline and Zhu, Peixin and Fishman, Mark (2019) Mating suppresses alarm response in zebrafish. Current biology. ISSN 1879-0445

Diaz Verdugo, Carmen and Sun, Gerald and Fawcett, Caroline and Zhu, Peixin and Fishman, Mark (2019) Mating suppresses alarm response in zebrafish. Current biology, 29. p. 2541. ISSN 1879-0445

Dierich, Marlen and Hartmann, Stephanie and Dietrich, Nadine and Moeser, Philip and Tziridis, Konstantin and Schilling, Achim and Krauss , Patrick and Brede, Franziska and Hessler, Sabine and Karch, Sandra and Oliver, Dominik and Moser, Tobias and Schultze, Holger and Alzheimer, Christian and Leitner, Michael and Huth, Tobias (2019) β-secretase BACE1 is required for normal cochlear function. The journal of neuroscience. ISSN 1529-2401

Dodd, Stephanie and Kollipara, Sivacharan and Heimbach, Tycho and Beato, Stefania and Sanchez-Felix, Manuel and Meng, Qingshuo (2019) Prediction of ARA/PPI Drug-Drug Interactions at the Drug Discovery and Development Interface. Journal of Pharmaceutical Sciences, 108 (1). pp. 87-101. ISSN 15206017

Dodge, Robert (2019) Gene Therapy: Bioanalytical Support and Strategies. AAPS Training webinar, NA (NA). NA-NA. ISSN NA

Doerning, Carolyn M and Thurston, Sarah E and Villano, Jason S and Kaska, Carian L and Vozheiko, Tracy D and Soleimanpour, Scott A and Lofgren, Jennifer L (2019) Assessment of Mouse Handling Techniques During Cage Changing. Journal of the American Association for Laboratory Animal Science : JAALAS. ISSN 1559-6109

Dranoff, Glenn and Dougan, Michael and Dougan, Stephanie (2019) GM-CSF, IL-3, and IL-5 Family of Cytokines: Regulators of Inflammation. Immunity, 50 (4). pp. 796-811. ISSN 10974180

Dörner, Thomas and Posch, Maximilian and Li, Yue and Petricoul, Olivier and Cabanski, Maciej and Valentin, Marie-Anne and Simonett, Claudia and Mooney, Louise and Gram, Hermann and Wagner, Frank and Oliver, Stephen (2019) Treatment of primary Sjögren’s syndrome with ianalumab (VAY736) Targeting B cells by BAFF receptor-blockade coupled with enhanced, antibody-dependent cellular cytotoxicity. Annals of the rheumatic diseases., 78 (5). pp. 641-647.

D’ATRI, Valentina and Pell, Reinhard and Clarke, Adrian and GUILLARME, Davy and FEKETE, Szabolcs (2019) Is hydrophobic interaction chromatography the most suitable technique to characterize site-specific antibody-drug conjugates? Journal of Chromatography A, 1586. pp. 149-153. ISSN 0021-9673

de Oliveira Mann, Carina and Orzalli, Megan and King, David and Kagan, Jonathan and Lee, Amy and Kranzusch, Philip (2019) Modular architecture of the STING C-terminal tail allows interferon and NF-κB signaling adaptation. Cell reports. ISSN 2211-1247

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Ecoeur, Florence and Weiss, Jessica and Kaupmann, Klemens and Hintermann, Samuel and Orain, David and Guntermann, Christine (2019) Antagonizing Retinoic acid-related-orphan receptor gamma Activity Blocks the T Helper 17/Interleukin-17 Pathway Leading to Attenuated Pro-inflammatory Human Keratinocyte and Skin Responses. Frontiers in Immunology, 10 (Front.).

Edge, Stephen and Morrical, Bradley and Singh, Dilraj and Lewis, David and Rouse, Tim and Shur, Jagdeep (2019) Defining the Dosage Strength for Labelling of DPIs: Use, Limitations and Relevance of in-vitro Data. Inhalation Magazine, 13 (Februa). pp. 7-13.

F

Faller, Bernard and Winiwarter, Susanne and Chang, George and Desai, Prashant and Menzel, Carsten and Rieko, Arimoto and Keefer, Christopher and Broccatelli, Fabio (2019) Prediction of fraction unbound in microsomal and hepatocyte incubations – a comparison of methods across industry data sets (by the IQ in silico ADME working group). Molecular pharmaceutics, 16 (9). pp. 4077-4085. ISSN 1543-8392; 1543-8384

Flannery, Erika and Markus, Miles and Vaughan, Ashley (2019) Parasite of the Month: Plasmodium vivax. Trends in Parasitology.

Flannery, Erika and Vaughan, Ashley (2019) Parasite of the Month: Plasmodium vivax. Trends in Parasitology.

Fukami, Shigemi and TOMIOKA, DAISAKU and Murakami, Yutaka and Honda, Toshiyuki and Hatakeyama, Shinji (2019) Pharmacological profiling of a dual FAK/IGF-1R kinase inhibitor TAE226 in cellular and in vivo models. BMC research notes, 12. p. 347. ISSN 1756-0500

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Gallou, Fabrice (2019) Bridging the gap between transition metal and biocatalysis. Nature, 10. p. 2169.

Gallou, Fabrice (2019) Coolade. A Low-Foaming Surfactant for Organic Synthesis in Water. ChemSusChem.

Gallou, Fabrice (2019) Fe-Catalyzed Reductive Couplings of Terminal (Hetero)Aryl Alkenes and Alkyl Halides under Aqueous Micellar Conditions. Journal of the American Chemical Society JACS., 141. pp. 17117-17124. ISSN https://pubs.acs.org/doi/pdf/10.1021/jacs.9b04510

Gallou, Fabrice (2019) Site selective amide reduction of cyclosporine A yields derivatives of an important cyclic peptide. organic letters, 21 (9). pp. 3451-3455.

Gallou, Fabrice (2019) Sustainability challenges in peptide synthesis and purification: from R&D to production. The journal of organic chemistry : JOC, 84 (8). pp. 4615-4628.

Gallou, Fabrice (2019) Sustainable ppm Level Palladium-Catalyzed Aminations Under Mild, Aqueous Nanomicellar Conditions. chemical science, 2019.

Gallou, Fabrice and Onken, Ulrich and Koettgen, Agnieszka and Scheidat, Holger (2019) Environmental metrics to drive a cultural change: our green eco-label. Chimia, 73 (9). pp. 730-736.

Gallou, Fabrice and Reilly, John (2019) A micellar-friendly, HandaPhos palladacycle pre-catalyst for ppm level Suzuki-Miyaura cross couplings in water under mild conditions. Chemical science, 10. pp. 8825-8831. ISSN 2041-6539; 2041-6520

Gill, Jonathan and Delezie, Julien and McGuirk, Shawn and Schnyder, Svenia and Gesa, Santos and Frank, Stephan and Rausch, Martin and Handschin, Christoph (2019) PGC-1α regulates mitochondrial-sarcoplasmic reticulum (SR)-mediated calcium exchange, SR stress and cell death to mitigate skeletal muscle aging. Aging cell. ISSN 1474-9726; 1474-9718

Giorgetti, Elisa and Obrecht, Michael and Ronco, Marie and Panesar, Moh and Lambert, Christian and Accart Gris, Nathalie and Doelemeyer, Arno and Nash, Mark and Bidinosti, Michael and Beckmann, Nicolau (2019) Magnetization Transfer Ratio (MTR) as a Non-Invasive Biomarker in Small Rodent Peripheral Nerve Injury Models. Scientific reports, 9 (1). p. 13508. ISSN 2045-2322

Glowienke, Susanne (2019) Genetic toxicology in silico protocol. Regulatory Toxicology and Pharmacology, 107. ISSN 10960295

Glowienke, Susanne and Parenty, Alexis (2019) Principles and procedures for handling out-of-domain and indeterminate results as part of ICH M7 recommended (Q)SAR analyses. Regulatory toxicology and pharmacology.

Glueck, Anton and Hueber, Wolfgang and Schlitt, Thomas and Hasselberg, Anke and Flannery, Brian and Wharton, Keith and Krueger, James and Suarez-Farinas, Mayte (2019) CAIN457A2223 12 week microarray data for upload to dbGaP. Journal of Allergy and Clinical Immunology.

Golding-Ochsenbein, Alexandra and Vidal, Solange and Wilmering Wetter, Barbara and Guibourdenche, Christel and Beerli, Christian and Chang, Lena and Leonhard, Sabine and Holway, Nicholas and Seuwen, Klaus and Jurisic Snijder, Giorgia (2019) S1P-S1PR1 activity controls VEGF-A signaling during lymphatic vessel development. bioRxiv. ISSN 10.1101/845396

Gomes, Luis and Hipp, Silvia and Upadhaya, Ajeet and Balakrishnan, Karthikeyan and Koper, Marta and Reichwald, Julia and Rabe, Sabine and Vandenberghe, Rik and von Arnim, Christine and Tousseyn, Thomas and Staufenbiel, Matthias and Thal, Dietmar Rudolf (2019) Aβ-induced acceleration of Alzheimer-related τ-pathology spreading and its association with prion protein. Acta Neuropathologica. ISSN 14320533

Gram, Hermann (2019) The long and winding road in pharmaceutical development of canakinumab, a human anti-IL-1 antibody. Pharmacological Research.

Greenidge, Paulette and Blommers, Marcel J.J. and Priestle, John Peter and Hunziker, Juerg (2019) How to Computationally Stack the Deck for Hit-to-Lead Generation: In Silico Molecular Interaction Energy Profiling for De Novo siRNA Guide Strand Surrogate Selection. Journal of chemical information and modeling, 59. pp. 1897-1908. ISSN 1549960X

Gudmundsdottir , Valborg and Emilsson, Valur and Aspelund, Thor and Ilkov, Marjan and Gudmundsson, Elias F and Zilhao, Nuno and Lamb, John and Jennings, Lori and Gudnason, Vilmundur (2019) Deep serum proteomics reveals biomarkers for prevalent and incident T2DM. Nature communications.

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Yeyinmen, Karen and Stacey, Mary (2019) Team Coaching at Scale: Creating conditions for the emergence of adaptive leadership cultures. The Practitioner's Handbook of Team Coaching. pp. 405-419. ISSN 978-1-351-13055-4

Z

Zerbi, Valerio and Markicevic, Marija and Gasparini, Fabrizio and Rudin, Markus and Wenderoth, Nicole (2019) Inhibiting mGluR5 activity by AFQ056/Mavoglurant rescues circuit-specific functional connectivity in Fmr1 knockout mice. NeuroImage, 191. pp. 392-402. ISSN 10959572

Zhou, Yingyao and Zhou, Bin and Pache, Lars and Chang, Max and Hadj Khodabakhshi, Alireza and Tanaseichuk, Olga and Benner, Chris and Chanda, Sumit (2019) Metascape provides a biologist-oriented resource for the analysis of systems-level datasets. Nature Communications, 10 (1). p. 1523. ISSN 20411723

This list was generated on Mon Dec 9 05:22:25 2019 UTC.

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