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Article

Accart Gris, Nathalie and Genoud, Christel (2019) Un premier pas vers l’étude du collagène du cartilage articulaire en microscopie électronique. Revue Française d'Histotechnologie, 31 (1). pp. 85-92. ISSN 0997-6434

Adams, Christopher, Stacy, Rebecca, Rangaswamy, Nalini, Bigelow, Chad, Grosskreutz, Cyndy and Prasanna, Ganesh (2019) Glaucoma - Next Generation Therapeutics: Impossible to Possible. Pharmaceutical Research, 36 (2). ISSN 1573904X

Aeffner, Famke, Zarella, Mark, Buchbinder, Nathan, Bui, Marilyn, Goodman, Matthew, Hartman, Douglas, Lujan, Giovanni, Molani, Mariam, Parwani, Anil, Tunstall, kate, Turner, Oliver, Vemuri, Venkata, Yuil-Valdes, Ana and Bowman, Douglas (2019) Introduction to Digital Image Analysis in Whole-Slide Imaging: A White Paper from the Digital Pathology Association. Journal of Pathology Informatics, 10 (9). pp. 1-17.

Aeschlimann, Samuel, Graf, Christian, Mayilo, Dmytro, Munschy, Helene, Urda, Lorena, Kappes, Nora, Simonis, Marieke, Splinter, Erik, van Min, Max and Laux, Holger (2019) Shortened abstract for Enhanced CHO clone screening using Next-Generation Sequencing and Targeted Locus Amplification publication. Enhanced CHO clone screening: Applying Targeted Locus Amplification and Next-Generation Sequencing technologies during cell line development.

Aguilar-de-Leyva, Ángela, Campiñez, Maria Dolores, Jost, Flavia, Gavira, Miguel and Caraballo, Isidoro (2019) Study of the critical points in combined matrix tablets containing both inert and swelling excipients. Journal of Drug Delivery Science and Technology, 52. pp. 885-894. ISSN 17732247

Aho, Erin R, Wang, Jing, Gogliotti, Rocco D, Howard, Gregory C, Phan, Jason, Acharya, Pankaj, Macdonald, Jonathan D, Cheng, Ken, Lorey, Shelly L, Lu, Bin, Wenzel, Sabine, Foshage, Audra M, Alvarado, Joseph, Wang, Feng, Shaw, J Grace, Zhao, Bin, Weissmiller, April M, Thomas, Lance R, Vakoc, Christopher R, Hall, Matthew D, Hiebert, Scott W, Liu, Qi, Stauffer, Shaun R, Fesik, Stephen W and Tansey, William P (2019) Displacement of WDR5 from Chromatin by a WIN Site Inhibitor with Picomolar Affinity. Cell reports, 26 (11). 2916-2928.e13. ISSN 2211-1247

Albiol, Laia, Büttner, Alexander, Pflanz, David, Mikolajewicz , Nicholas, Birkhold, Annette I., Kramer, Ina, Kneissel, Michaela, Duda, Georg, Checa, Sara and Willie, Bettina M. (2019) Effects of Long-Term Sclerostin Deficiency on Trabecular Bone Mass and Adaption to Limb Loading Differ in Male and Female Mice. Calcified tissue international.

Alexander, Schuhmacher, Oliver, Gassmann, Michael, Kuss and Hinder, Markus (2019) The Art of Virtualizing Pharma R&D. Drug Discovery Today. pp. 1-2. ISSN 18785832

Altshuler, Bob (2019) Research summary for postdoc program mentor profile. NIBR Postdoc Program.

Ando, Yuichi, Iwasa, Satoru, Takahashi, Shunji, Saka, Hideo, KAKIZUME, TOMOYUKI, NATSUME, KAZUTO, NOUMI, NAOKO, Quadt, Cornelia and Yamada, Yasuhide (2019) Phase I study of alpelisib (BYL719), an α-specific PI3K inhibitor, in Japanese patients with advanced solid tumors. Cancer Science. ISSN 13497006

Arias, HR, Jin, X-T, Peng, C, Feuerbach, Dominik, Ortells, MO, Elgoyhen, AB and Drenan, RM (2019) Selectivity of (±)-citalopram at nicotinic acetylcholine receptors and different inhibitory mechanisms between habenular α3β4* and α9α10 subtypes. Neurochemistry international.

Arias, Hugo R, Ortells, Marcelo O, Feuerbach, Dominik, Burgos, Viviana and Paz, Cristian (2019) Alkaloids purified from the Aristotelia chilensis tree inhibit the human α3β4 nicotinic acetylcholine receptor with higher potency compared to human α4β2 and α7 subtypes. Journal of natural products.

Arista, Luca, Ullrich, Thomas, Riela, Serena, Massaro, Marina, Buscemi, Gabriella, Biddeci, Giuseppa, Cavallaro, Giuseppe, D'Anna, Francesca, Di Blasi, Francesco, Ferrante, Angelo, Lazzara, Giuseppe, Rizzo, Carla and Spinelli, Gaetano (2019) Multifunctional carrier based on halloysite/laponite hybrid hydrogel for kartogenin delivery. ACS Medicinal Chemistry Letters, 2019 (10). pp. 419-424. ISSN 1948-58751948-5875

Arora, Rishi, Nimonkar, Amitabh, Baird, Daniel, Wang, Chunhua, Chiu, Chun-Hao, Horton, Patricia, Hanrahan, Susan, Cubbon, Rose, Weldon, Stephen, Tschantz, Bill, Mueller, Sascha, Brunner, Reto, Lehr, Philipp, Meier, Peter, Ottl, Johannes, Voznesensky, Andrei, Pandey, Pramod, Smith, Thomas, Stojanovic, Aleksandar, Flyer, Alec, Benson, Timothy, Romanowski, Michael and Trauger, John (2019) Structure of lipoprotein lipase in complex with GPIHBP1. Proceedings of the National Academy of Sciences of the United States of America, 116 (21). pp. 10360-10365. ISSN 10916490

Arora, Rishi, Nimonkar, Amitabh V, Baird, Daniel, Wang, Chunhua, Chiu, Chun-Hao, Horton, Patricia A, Hanrahan, Susan, Cubbon, Rose, Weldon, Stephen, Tschantz, William R, Mueller, Sascha, Brunner, Reto, Lehr, Philipp, Meier, Peter, Ottl, Johannes, Voznesensky, Andrei, Pandey, Pramod, Smith, Thomas M, Stojanovic, Aleksandar, Flyer, Alec, Benson, Timothy E, Romanowski, Michael J and Trauger, John W (2019) Structure of lipoprotein lipase in complex with GPIHBP1. Proceedings of the National Academy of Sciences of the United States of America. ISSN 1091-6490

Arora, Rishi, Nimonkar, Amitabh V, Baird, Daniel, Wang, Chunhua, Chiu, Chun-Hao, Horton, Patricia A, Hanrahan, Susan, Cubbon, Rose, Weldon, Stephen, Tschantz, William R, Mueller, Sascha, Brunner, Reto, Lehr, Philipp, Meier, Peter, Ottl, Johannes, Voznesensky, Andrei, Pandey, Pramod, Smith, Thomas M, Stojanovic, Aleksandar, Flyer, Alec, Benson, Timothy E, Romanowski, Michael J and Trauger, John W (2019) Structure of lipoprotein lipase in complex with GPIHBP1. Proceedings of the National Academy of Sciences of the United States of America, 116 (21). pp. 10360-10365. ISSN 1091-6490

Artim, Stephen C, Sheh, Alexander, Burns, Monika A and Fox, James G (2019) Evaluating rectal swab collection method for gut microbiome analysis in the common marmoset (Callithrix jacchus). PloS one, 14 (11). e0224950. ISSN 1932-6203

Auberson, Yves (2019) An Element of Community: EFMC, the European Federation for Medicinal Chemistry. Chimia..

Babrak, Lmar M., Menetski, Joseph, Rebhan, Michael, Nisato, Giovanni, Zinggeler, Marc, Brasier, Noe, Baerenfaller, Katja, Brenzikofer, Thomas, Baltzer, Laurenz, Vogler, Christian, Gschwind, Leo, Schneider, Cornelia, Streiff, Fabian, Groenen, Peter M.A. and Miho, Enkelejda (2019) Traditional and digital biomarkers - two worlds apart? Digital Biomarkers, 3 (2). pp. 92-102. ISSN 2504-110X

Baenziger, Markus, Eswaran, Sumesh, Kanasithan, Gopu and Jiang, Yifan (2019) Selective ortho -Metalation of a Fluoroarene with Knochel-Hauser Base and Reactions with Various Electrophiles. Synthesis (Germany), 51 (7). pp. 1649-1654. ISSN 1437210X

Baenziger, Markus, Pachinger, Werner, Stauffer, Frederic and Zaugg, Werner (2019) Development of the synthesis of BEZ235 on ton scale. Organic Process Research & Development, 23 (9). pp. 1908-1917. ISSN 1083-61601520-586X

Bagdanoff, Jeffrey, Acker, Michael, Chan, Ho Man, Dore, Michael, Firestone, Brant, Fodor, Michelle, Garcia Fortanet, Jorge, Hentemann, Martin, Kato, Mitsunori, Koenig, Robert, La Bonte, Laura, Liu, Shumei, Chen, Zhuoliang, Chen, Ying-Nan, Mohseni, Mori, Ntaganda, Rukundo, Sarver, Patrick, Smith, Troy, Sendzik, Martin, Stams, Travis, Spence, Stan, Towler, Christopher, Wang, Hongyun, Wang, Ping and Williams, Sarah (2019) Optimization of Fused Bicyclic Allosteric SHP2 Inhibitors. Journal of Medicinal Chemistry, 62 (4). pp. 1781-1792. ISSN 15204804

Baltschukat, Sabrina, Schacher Engstler, Barbara, Huang, Alan, Hao, Huaixiang, Tam, Angela, Wang, Hui-Qin, Liang, Jinsheng, Dimare, Matt, Bhang, Hyo-Eun, Wang, Youzhen, Furet, Pascal, Sellers, William, Hofmann, Francesco, Schoepfer, Joseph and Tiedt, Ralph (2019) Capmatinib (INC280) is active against models of non–small cell lung cancer and other cancer types with defined mechanisms of MET activation. Clinical Cancer Research, 25 (10). pp. 3164-3175. ISSN 15573265

Bassilana, Frederic, Nash, Mark and Ludwig, Marie-Gabrielle (2019) Adhesion G protein-coupled receptors: opportunities for drug discovery. Nature reviews drug discovery.

Beck, Katharina R., Kanagaratnam, Sharavan, Kratschmar, Denise V., Birk, Julia, Yamaguchi, Hideaki, Sailer, Andreas, Seuwen, Klaus and Odermatt, Alex (2019) Enzymatic interconversion of the oxysterols 7β,25-dihydroxycholesterol and 7-keto,25-hydroxycholesterol by 11β-hydroxysteroid dehydrogenase type 1 and 2. Journal of steroid biochemistry and molecular biology, 190. pp. 19-28. ISSN 1879-1220

Bednarczyk, Dallas and Sanghvi, Menaka (2019) The impact of assay recovery on the apparent permeability, a function of lysosomal trapping. Xenobiotica; the fate of foreign compounds in biological systems. pp. 1-22. ISSN 13665928

Bernink, Jochem H, Ohne, Yoichiro, Teunissen, Marcel BM, wang, Jingya, wu, Jincheng, krabbendam, lisette, Guntermann, Christine, volckmann, richard, koster, jan, van Tol, sophie, ramirez, ivan, shrestha, yashaswi, de rie, menno a, spits, hergen, ros, xavier romero and humbles, alison a (2019) c-Kit-positive ILC2s exhibit an ILC3-like signature that may contribute to IL-17-mediated pathologies. Nature immunology. ISSN 1529-2916

Berrien-Elliott, Melissa M., Sun, Yaping, Neal, Carly, Ireland, Aaron, Trissal, Maria C., Sullivan, Ryan, Wagner, Julia A., Leong, Jeffrey W., Wong, Pamela, Mah-Som, Annelise Y., Wong, Terrence N., Schappe, Timothy, Keppel, Catherine R., Cortez, Victor S., Stamatiades, Efstathios G., Li, Ming O., Colonna, Marco, Link, Daniel C., French, Anthony R., Cooper, Megan A., Wang, Wei-Le, Boldin, Mark P., Reddy, Pavan and Fehniger, Todd A. (2019) MicroRNA-142 Is Critical for the Homeostasis and Function of Type 1 Innate Lymphoid Cells. Immunity. ISSN 10747613

Bhhatarai, Barun, Walters, Patrick, Hop, Cornelis, Lanza, Guido and Ekins, Sean (2019) Opportunities and Challenges Using Artificial Intelligence (AI) in ADME/Tox. Nature materials., 18. pp. 418-422. ISSN 1476-1122

Bill, Anke, Yeboah, Fred, Kim, Tae-Eu and Dettmer, Ulf (2019) Dynamic behaviors of α-synuclein and tau in the cellular context: New mechanistic insights and therapeutic opportunities in neurodegeneration. Neurobiology of Disease, 132. ISSN 1095953X

Borsari, Chiara, Rageot, Denise, Dall’Asen, Alix, Bohnacker, Thomas, Melone, Anna, Sele, Alexander M., Jackson, Eileen, Langlois, Jean-Baptiste, Beaufils, Florent, Hebeisen, Paul, Fabbro, Doriano, Hillmann, Petra and Wymann, Matthias P. (2019) A Conformational Restriction Strategy for the Identification of a Highly Selective Pyrimido-pyrrolo-oxazine mTOR Inhibitor. Journal of Medicinal Chemistry, 62 (18). pp. 8609-8630. ISSN 0022-2623

Bova, Kaitlin (2019) USP 800: Protecting Site Staff from Hazardous Drugs. Clinical Trial Supply Handbook .

Braun , Marie-Gabrielle , Díaz-Rodríguez, Alba , Diorazio, Louis , Fraunhoffer, Kenneth , Hayler, John , Hickey, Matthew , Lovelle, Lucie, McLaws, Mark , Parsons, Andrew , Richardson, Paul , Roiban, Doru , Steven, Alan , Terrett, Jack , White , Timothy and Yin, Jingjun (2019) Green Chemistry Articles of Interest to the Pharmaceutical Industry. Organic Process Research & Development, 23 (11). pp. 2287-2301. ISSN 1083-61601520-586X

Briard, Emmanuelle, joshi, Aniket, Shanmukhappa, Shiva, Ilovich, Olav and Auberson, Yves (2019) [18F]PRIMATX, a New Positron Emission Tomography Tracer for Imaging of Autotaxin in Lung Tissue and Tumor‐Bearing Mice. ChemMedChem.

Brock, Ansgar, Venable, John, Steckler, Caitlin and Park, In Hee (2019) Interlaboratory Comparison of Hydrogen-Deuterium Exchange Mass Spectrometry Measurements of the Fab fragment of NISTmAb. Analytical chemistry. ISSN 0003-2700

Bruch, Richard, Baaske, Julia, Chatelle, Claire, Meirich, Mailin, Madlener, Sibylle, Weber, Wilfried, Dincer, Can and Urban, Gerald Anton (2019) CRISPR/Cas13a‐powered electrochemical microfluidic biosensor for nucleic acid amplification‐free miRNA diagnostics. Advanced Materials. p. 1905311. ISSN 0935-9648

Bruin, Gerardus, Hasselberg, Anke, Korolova, Irena, Milojevic, Julie, Calonder, Claudio, Soon, Rachel, Woessner, Ralph, Pariser, David and Boutouyrie-Dumont, Bruno (2019) Secukinumab treatment does not alter the pharmacokinetics of the CYP3A4 substrate midazolam in patients with moderate to severe psoriasis – results from an open label disease-drug-drug interaction study. Clinical pharmacology and therapeutics, Early (Early ).

Burger, Matthew, Aversa, Robert, Taft, Benjamin, La Bonte, Laura, Cooke, Vesselina, Polyakov, Valery, Mishina, Yuji, Haling, Jake, Tellew, John, Iyer, Raman, Tian, Hung, Mathews Griner, Lesley, Mamo, Mulugeta, Huang, Shenlin, Gampa, Kalyani and Feng, Fei (2019) Design and Discovery of N-(3-(2-(2-hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide (LXH254), A selective, efficacious, well-tolerated RAF inhibitor targeting RAS mutant cancers: The path to the clinic. Journal of medicinal chemistry, 63 (5). pp. 2013-2027.

Burns, Michael, Ott, Martin, Teasdale, Andrew, Stalford, Susanne, Antonucci, Vincent, Baumann, Jens-Christoph, Brown, Roland, Covey-Crump, Elisabeth, Elder, David, Elliott, Eric, Fennell, Jarred, Gallou, Fabrice, Ide, Nathan, Itoh, Tetsuji, Jordine, Guido, Kallemeyn, Jeffrey, Lauwers, Dick, Looker, Adam, Lovelle, Lucie, Molzahn, Robert, Schills, Didier, Schulte Oestrich, Rolf, Sluggett, Gregory, Stevenson, Neil, Talavera, Pere, Urquhart, Michael, Varie, David and Welch, Dennie (2019) A New Semi-Automated Computer-Based System for Assessing the Purge of Mutagenic Impurities. Organic process research & development.

Bussiere, Dirksen, Beckwith, Rohan, Be, Celine, Burke, Ashley, Carte, Nathalie, Cobb, Jennifer, Fazal, Aleem, Frank, Andreas, Frommlet, Alexandra, Godbole, Adarsh, Graff, Patrick, Hornak, Viktor, King, Daniel, Knapp, Mark, Paulk, Josh, Shu, Wei, Solomon, Jonathan, Srinivas, Honnappa, Voshol, Johannes, Wiesmann, Christian, Xie, Lili, Xu, Fangmin, Zhao, Junping, Okram, Barun, Jiang, Songchun, Michellys, Pierre and Karki, Rajeshri (2019) Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex. Nature chemical biology. ISSN 1552-4469; 1552-4450

Cadena, Cristhian, Ahmad, Sadeem, Xavier, Audrey, Willemsen, Joschka, Park, Sehoon, Park, Ji Woo, Oh, Seong-Wook, Fujita, Takashi, Hou, Fajian, Binder, Marco and Hur, Sun (2019) Ubiquitin-Dependent and -Independent Roles of E3 Ligase RIPLET in Innate Immunity. Cell, 177 (5). 1187-1200.e16. ISSN 1097-4172

Cadena, Samuel, Choi, Sungshin, Saravia-Butler, Amanda, Shirazi-Fard, Yasaman, Leveson-Gower, Dennis, Stodieck, Louis, Beegle, Janet, Solis, Stephanie, Ronca, April and Globus, Ruth (2019) Behavior of mice aboard the International Space Station. Scientific reports, 9 (1). ISSN 20452322

Cadena, Samuel, Zhang, Yunyu, Lemire, Sophie, Kuss, Pia, Giorgetti, Elisa, Kneissel, Michaela, Glass, David and Stodieck, Louis (2019) Skeletal muscle in MuRF1 null mice is not spared in low-gravity conditions, indicating atrophy proceeds by unique mechanisms in space. Skeletal muscle in MuRF1 null mice is not spared in low-gravity conditions, indicating atrophy proceeds by unique mechanisms in space , 9 (1). p. 9397. ISSN 2045-2322

Camenisch, Gian P. (2019) DRUG-INDUCED LIVER INJURY PREDICTIONS: EXTENDED CLEARANCE MODEL AND ITS USE FOR PROPSPECTIVE TRANSPORTER- AND ENZYME-BASED HEPATIC CELL STRESS GRADING. International Journal of Pharmacy and Chemistry, 5 (2). pp. 15-19. ISSN 2575-5730

Canham, Steve, Russ, Carsten, Reece-Hoyes, John and Sigoillot, Frederic (2019) Bile acid analogues are activators of pyrin inflammasome. Journal of Biological Chemistry, 294 (10). pp. 3359-3366. ISSN 0021-92581083-351X

Carballido, Jose and Santamaria, Pere (2019) Taming autoimmunity: Translating antigen-specific approaches to induce immune tolerance. The Journal of Experimental Medicine. ISSN 0022-10071540-9538

Chapeau, Emilie, Mandon, Emeline, Romanet, Vincent, Ebel, Nicolas, Gill , Jason, Powajbo, Violetta, Andraos-Rey, Rita, Qian, Zhiyan, Kininis, Miltiadis, Zumstein-Mecker, Sabine, Ito, Moriko, Hynes, Nancy, Hofmann, Francesco, Tiedt, Ralph, Eshkind, Leonid , Bockamp, Ernesto , Kinzel, Bernd, Mueller, Matthias, Murakami, Masato, Baffert, Fabienne and Radimerski, Thomas (2019) A conditional inducible JAK2V617F transgenic mouse model reveals myeloproliferative disease that is reversible upon switching off transgene expression. PLoS ONE, 14 (10). ISSN 1932-6203

Chen, Kaiwen, Demarco, Benjamin, Shkarina, Kateryna, Boettcher, Andreas, Farady, Christopher, Heilig, Rosalie, Broz, Petr and Pelzcar, P (2019) Extrinsic and intrinsic apoptosis activate pannexin-1 to drive NLRP3 inflammasome assembly. EMBO Journal. ISSN 14602075

Chen, Lieyang, Cruz, Anthony, Ramsey, Steven, Dickson, Callum, Duca, Jose, Hornak, Viktor, Koes, David and Kurtzman, Tom (2019) Hidden bias in the DUD-E dataset leads to misleading performance of deep learning in structure-based virtual screening. PLoS ONE, 14 (8). ISSN 19326203

Chen1, Lisa S., Keating, Michael J., Wierda, William G. and Gandhi, Varsha V. (2019) Induction of apoptosis by MCL-1 inhibitors in chronic lymphocytic leukemia cells. Leukemia & lymphoma, 60. pp. 3063-3066. ISSN 1029-2403

Chiang, Derek, Leary, Rebecca, Wong, Connie, Singh, Angad and Charette, LaSalette (2019) A community-based lung cancer rapid tissue donation protocol provides high-quality drug-resistant specimens for proteogenomic analyses. Cancer Medicine. ISSN 20457634

Christian, Alec H, Jia, Shang, Zhang, Patricia, Tena Meza, Arismel, Sigman, Matthew S, Chang, Christopher J and Toste, F Dean (2019) A Physical Organic Approach to Tuning Reagents for Selective and Stable Methionine Bioconjugation. Journal of the American Chemical Society JACS., 141 (32). pp. 12657-12662. ISSN 0002-78631520-5126

Clavaud, Matthieu, Lema-Martinez, Carmen, Roggo, Yves, Bigalke, Michael, Guillemain, Aurélie, Hubert, Philippe, Ziemons, Eric and Allmendinger, Andrea (2019) Near-infrared spectroscopy to determine residual moisture in freeze-dried products: model generation by statistical design of experiments. Journal of Pharmaceutical Sciences. ISSN 00223549

Cooner, Freda, Gamalo-Siebers, Margaret, Xia, Amy, Aijun, Gao, Ruan, Shiling, Tony, Jiang and Laura, Thompson (2019) Use of Alternative Designs and Data Sources for Pediatric Trials. Statistics in Biopharmaceutical Research. ISSN 19466315

Costa, Carlotta, Ly, Amy, Walmsley, Charlotte S., Huynh, Tiffany, Healy, Christopher, Peterson, Rachel, Jakubik, Charles T., Henderson, Laura E., Ho, Jeffrey, Timotina, Daria, Sanidas, Ioannis, Veloso, Artur, Mino-Kenudson, Mari, Stone, James R., Dyson, Nick, Benes, Cyril H., Engelman, Jeffrey and Dejan, Juric (2019) PTEN loss mediates clinical cross-resistance to CDK4/6 and PI3Kα inhibitors in breast cancer. Cancer discovery. ISSN 21598290

Cryer, Alexander M, Chan, Cheuk, Eftychidou, Anastasia, Maksoudian, Christy, Mahesh, Mohan, Tetley, Teresa D, Spivey, Alan C and Thorley, Andrew J (2019) Tyrosine Kinase Inhibitor Gold Nanoconjugates for the Treatment of Non-Small Cell Lung Cancer. ACS applied materials & interfaces, 11 (18). pp. 16336-16346. ISSN 1944-8252

Cryer, Alexander M and Thorley, Andrew J (2019) Nanotechnology in the diagnosis and treatment of lung cancer. Pharmacology & therapeutics, 198. pp. 189-205. ISSN 1879-016X

D'Alessandro, Pier Luca, Hollingworth, Greg and Vorherr, Thomas (2019) Real-Time Imaging and Quantification of Peptide Uptake in Vitro and in Vivo. ACS Chemical Biology, 14 (10). pp. 2197-2205. ISSN 15548937

D'Alessandro, Pier Luca, Hollingworth, Greg and Vorherr, Thomas (2019) Real-time imaging and quantification of peptide uptake in vitro and in vivo. ACS Chemical Biology. ISSN 1554-89291554-8937

Dalvit, Claudio and Vulpetti, Anna (2019) Ligand-Based Fluorine NMR Screening: Principles and Applications in Drug Discovery Projects. Journal of Medicinal Chemistry, 62. pp. 2218-2244. ISSN 15204804

Daniela, Mercatelli, Bolognesi, Paolo, Frassineti, Martina, Clarissa, Pisanò, Francesco, Longo, Shimshek, Derya and Michele, Morari (2019) Leucine-rich repeat kinase 2 (LRRK2) inhibitors differentially modulate glutamate release and Serine935 LRRK2 phosphorylation in striatal and cerebrocortical synaptosomes. Pharmacology Research & Perspectives, 7 (3). ISSN 2052-17072052-1707

Darpo, B, Benson, C, Dota, C and Jarugula, Venkateswar (2019) Evaluation of the Effect of 5 QT-Positive Drugs on the JTpeak Interval — An Analysis of ECGs From the IQ-CSRC Study. Journal of Clinical Pharmacology. ISSN 15524604

Deodato, Giacomo, Ball, Christopher and Zhang, Xian (2019) Bayesian Neural Networks for Cellular Image Classification and Uncertainty Analysis. www.biorxiv.org.

Desjardins, Pascale, Couture, Camille, Germain, Lucie and Guérin, Sylvain (2019) Contribution of the WNK1 kinase to corneal wound healing using the tissue-engineered human cornea as an in vitro model. Biomaterials.

Diaz Verdugo, Carmen, Sun, Gerald, Fawcett, Caroline, Zhu, Peixin and Fishman, Mark (2019) Mating suppresses alarm response in zebrafish. Current biology. ISSN 1879-0445

Diaz Verdugo, Carmen, Sun, Gerald, Fawcett, Caroline, Zhu, Peixin and Fishman, Mark (2019) Mating suppresses alarm response in zebrafish. Current biology, 29. p. 2541. ISSN 1879-0445

Dickson, Callum, Velez-Vega, Camilo and Duca, Jose (2019) Revealing molecular determinants of hERG blocker and activator binding. Journal of chemical information and modeling. ISSN 1549960X

Dierich, Marlen, Hartmann, Stephanie, Dietrich, Nadine, Moeser, Philip, Tziridis, Konstantin, Schilling, Achim, Krauss , Patrick, Brede, Franziska, Hessler, Sabine, Karch, Sandra, Oliver, Dominik, Moser, Tobias, Schultze, Holger, Alzheimer, Christian, Leitner, Michael and Huth, Tobias (2019) β-secretase BACE1 is required for normal cochlear function. The journal of neuroscience. ISSN 1529-2401

Dodd, Stephanie, Kollipara, Sivacharan, Heimbach, Tycho, Beato, Stefania, Sanchez-Felix, Manuel and Meng, Qingshuo (2019) Prediction of ARA/PPI Drug-Drug Interactions at the Drug Discovery and Development Interface. Journal of Pharmaceutical Sciences, 108 (1). pp. 87-101. ISSN 15206017

Dodge, Robert (2019) Gene Therapy: Bioanalytical Support and Strategies. AAPS Training webinar, NA (NA). NA-NA. ISSN NA

Doerning, Carolyn M, Thurston, Sarah E, Villano, Jason S, Kaska, Carian L, Vozheiko, Tracy D, Soleimanpour, Scott A and Lofgren, Jennifer L (2019) Assessment of Mouse Handling Techniques During Cage Changing. Journal of the American Association for Laboratory Animal Science : JAALAS. ISSN 1559-6109

Dranoff, Glenn, Dougan, Michael and Dougan, Stephanie (2019) GM-CSF, IL-3, and IL-5 Family of Cytokines: Regulators of Inflammation. Immunity, 50 (4). pp. 796-811. ISSN 10974180

Duca, Jose, Jansen, Hanneke, Schneider, Petra, Walters, W. Patrick, Plowright, Alleyn T., Sieroka, Norman , Fisher, Jasmin , Listgarten, Jennifer , Goodnow, Jr., Robert A. , Rush, Thomas S. , Zentgraf, Matthias , Hill, John Edward , Krutoholow, Elizabeth , Kohler, Matthias , Luebkemann, Chris, Blaney, Jeff , Funatsu, Kimito and Schneider, Gisbert (2019) Rethinking drug design in the artificial intelligence era. Nature Reviews Drug Discovery. ISSN 14741784

Duvadie, Rohit, Robinson, Richard, Altinoglu, Erhan, Jensen, Klavs, Pomberger, Alexander, Mo, Yiming, Nandiwale, Kakasaheb and Schultz, Victor (2019) A Continuous Stirred-Tank Reactor (CSTR) Cascade for Handling Solid-Containing Photochemical Reactions. Organic process research & development, 23 (12). pp. 2699-2706.

Dörner, Thomas, Posch, Maximilian, Li, Yue, Petricoul, Olivier, Cabanski, Maciej, Valentin, Marie-Anne, Simonett, Claudia, Mooney, Louise, Gram, Hermann, Wagner, Frank and Oliver, Stephen (2019) Treatment of primary Sjögren’s syndrome with ianalumab (VAY736) Targeting B cells by BAFF receptor-blockade coupled with enhanced, antibody-dependent cellular cytotoxicity. Annals of the rheumatic diseases., 78 (5). pp. 641-647.

D’ATRI, Valentina , Pell, Reinhard, Clarke, Adrian, GUILLARME, Davy and FEKETE, Szabolcs (2019) Is hydrophobic interaction chromatography the most suitable technique to characterize site-specific antibody-drug conjugates? Journal of Chromatography A, 1586. pp. 149-153. ISSN 0021-9673

Ecoeur, Florence, Weiss, Jessica, Kaupmann, Klemens, Hintermann, Samuel, Orain, David and Guntermann, Christine (2019) Antagonizing Retinoic acid-related-orphan receptor gamma Activity Blocks the T Helper 17/Interleukin-17 Pathway Leading to Attenuated Pro-inflammatory Human Keratinocyte and Skin Responses. Frontiers in Immunology, 10 (Front.).

Edge, Stephen, Morrical, Bradley, Singh, Dilraj, Lewis, David, Rouse, Tim and Shur, Jagdeep (2019) Defining the Dosage Strength for Labelling of DPIs: Use, Limitations and Relevance of in-vitro Data. Inhalation Magazine, 13 (Februa). pp. 7-13.

Emilsson, Valur, Gudnason, Vilmundur and Jennings, Lori (2019) Predicting health and life span with the deep plasma proteome. Nature Medicine, 25 (12). pp. 1815-1816. ISSN 1546170X

Erlanson, Daniel A., Davis, Ben J. and Jahnke, Wolfgang (2019) Fragment-Based Drug Discovery: Advancing Fragments in the Absence of Crystal Structures. Cell Chemical Biology, 26 (1). pp. 9-15. ISSN 24519448

Ertl, Peter and Schuhmann, Tim (2019) A Systematic Cheminformatics Analysis of Functional Groups Occurring in Natural Products. Journal of natural products, 82 (5). pp. 1258-1263. ISSN 1520-6025

Ertl, Peter, van Deursen, Ruud, Tetko, Igor V and Godin, Guillaume (2019) GEN: Highly Efficient SMILES Explorer Using Autodidactic Generative Examination Networks. arXiv.

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Wu, Paul, Hartman, Taymar, Almond, Louise, Stevens, Jennitte, Thrift, John, Ojha, Juhi, Alves, Christina, Shaw, David, Laird, Mike, Emmins, Robyn, Zhu, Yuan, Liu, Ren, Du, Zhimei, Koehler, Rolf, Jostock, Thomas, Anderson, Karin, Campbell, Chris and Clarke, Howard (2019) Advancing Biologics Development Programs with Legacy Cell Lines: Advantages and Limitations of Genetic Testing for Addressing Clonality Concerns Prior to Availability of Late Stage Process and Product Consistency Data. PDA journal of pharmaceutical science and technology. ISSN 19482124

Wyss, Annika, Rasseli, Tina, Perkins, Nathan, Ruiz, Florian, Schmelczer, Gerard, Klinke, Glynis, Moncsek, Anja, Roth, Rene, Spalinger, Marianne, Hering, Larissa, Atrott, Kirstin, Lang, Silvia, Frey-Wagner, Isabelle, Mertens, Joachim, Scharl, Michael, Sailer, Andreas, Pabst, Oliver, Hersberger, Martin, Pot, Caroline, Rogler, Gerhard and Misselwitz, Benjamin (2019) The EBI2-oxysterol axis promotes the development of intestinal lymphoid structures and colitis. Mucosal immunology. ISSN 1935-3456

Yamaura, Takeshi, Kasaoka, Tatsuhiko, KANEKO, NAOKO, Kimura, Masaaki and Hatakeyama, Shinji (2019) Evaluation of therapeutic effects of FAK inhibition in murine models of atherosclerosis. BMC research notes, 12. p. 200. ISSN 1756-0500

Yeyinmen, Karen and Stacey, Mary (2019) Team Coaching at Scale: Creating conditions for the emergence of adaptive leadership cultures. The Practitioner's Handbook of Team Coaching. pp. 405-419. ISSN 978-1-351-13055-4

Zerbi, Valerio, Markicevic, Marija, Gasparini, Fabrizio, Rudin, Markus and Wenderoth, Nicole (2019) Inhibiting mGluR5 activity by AFQ056/Mavoglurant rescues circuit-specific functional connectivity in Fmr1 knockout mice. NeuroImage, 191. pp. 392-402. ISSN 10959572

Zhou, Yingyao, Zhou, Bin, Pache, Lars, Chang, Max, Hadj Khodabakhshi, Alireza, Tanaseichuk, Olga, Benner, Chris and Chanda, Sumit (2019) Metascape provides a biologist-oriented resource for the analysis of systems-level datasets. Nature Communications, 10 (1). p. 1523. ISSN 20411723

de Oliveira Mann, Carina, Orzalli, Megan, King, David , Kagan, Jonathan, Lee, Amy and Kranzusch, Philip (2019) Modular architecture of the STING C-terminal tail allows interferon and NF-κB signaling adaptation. Cell reports. ISSN 2211-1247

van Keulen, Danielle, Pouwer, Marianne G., Emilsson, Valur, Aldi, Silvia, Perisic Matic, Ljubica, Hedin, Ulf, Gudnason, Vilmundur, Jennings, Lori, Holstrom, Kim, Schnack Nielson, Boye, Pasterkamp, Gerard, Lindeman, Jan H.N., van Gool, Alain J., Sollewijn Gelpke, Maarten D., Princen, Hans M.G. and Tempel, Dennie (2019) Oncostatin M reduces atherosclerosis development in APOE3Leiden.CETP mice and is associated with increased survival probability in humans. PLoS ONE, 14 (8). pp. 1-22. ISSN 19326203

vitobello, Antonio, Perner, Juliane, Beil, Johanna, Zhu, Jiang, Del Rio Espinola, Alberto, Morawiec, Laurent, Westphal, Magdalena, Dubost, Valerie, Altorfer, Marc, Naumann, Ulrike, Mueller, Arne, Kapur, Karen, Borowsky, Mark, Henderson, Colin, Wolf, Roland, Schwarz, Michael, Moggs, Jonathan and Terranova, Remi (2019) Drug-induced chromatin accessibility changes associate with sensitivity to liver tumor promotion. Life Science Alliance.

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This list was generated on Sat Nov 23 01:31:47 2024 UTC.

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