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Coolade. A Low-Foaming Surfactant for Organic Synthesis in Water

Gallou, Fabrice (2019) Coolade. A Low-Foaming Surfactant for Organic Synthesis in Water. ChemSusChem.


Several types of reduction reactions in organic synthesis run under aqueous micellar catalysis conditions (i.e., in water at ambient temperatures) produce significant volumes of foam due to the combination of the surfactant being used in the presence of gas evolution. The newly engineered surfactant “Coolade” minimizes this important technical issue due to its low-foaming properties. Coolade is the latest in a series of designer surfactants specifically tailored to enable organic synthesis in water. We herein report the synthesis of this new surfactant along with its applications to gas-involving reactions.

Item Type: Article
Date Deposited: 02 Jul 2019 00:45
Last Modified: 02 Jul 2019 00:45


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