Items where Year is 2017
A
Abraham, Yann, Gerrits, Bertran, Rebhan, Michael, Ludwig, Marie-Gabrielle and Gubser Keller, Caroline (2017) Exploring Glucocorticoid Receptor Agonists Mechanism of Action Through Mass Cytometry and Radial Visualizations. Cytometry. Part B : clinical cytometry., 92 (1). pp. 42-56. ISSN 1552-4957; 1552-4949
Altmann, Eva, Erbel, Paulus, Renatus, Martin, Schaefer, Michael, Schlierf, Anita, Druet, Adelaide, Kieffer, Laurence, Sorge, Mickael, Pfister, Keith, Hassiepen, Ulrich, Ostermeier, Daniela, Martoglio, Bruno, Jefferson , Anne B. and Ruedisser, Simon (2017) Azaindoles as Zinc-Binding Small-Molecule Inhibitors of the JAMM Protease CSN5. Chimia., 71 (4). p. 241. ISSN 10.2533/chimia2017.241
Altmann, Eva, Schlierf, Anita, Schaefer, Michael, Renatus, Martin, Ruedisser, Simon, Erbel, Paulus, Ostermeier, Daniela, Druet, Adelaide, Kieffer, Laurence, Sorge, Mickael, Hassiepen, Ulrich, Jones, Matthew, Pfister, Keith, Jefferson, Ann, Martoglio, Bruno and Quancard, Jean (2017) Azaindoles as zinc-binding small molecule inhibitors of the JAMM protease CSN5. Angewandte Chemie, 56 (5). pp. 1294-1297. ISSN 1433-7851
Ambrose, Jessi, Mapa, Felipa, Ross, Nathan, Chen, Julie, Ye, Chaoyang and Bilican, Bilada (2017) Automated Scale-up and Maintenance of Stem Cell-Induced Neurons for Long-Term Culture and High-Throughput Screening. SLAS Technology.
Amsler, Philipp, Heudi, Olivier, Lanshoeft, Christian, Bettighofer, Anja, Eisfeld, Jochen, Moenius, Thomas, Probst, Claudia Monika and Etter, Coralie (2017) Production and application of high quality stable isotope labeled monoclonal antibody for mass spectrometry analysis. Journal of labelled compounds and radiopharmaceuticals. ISSN 03624803
Argikar, Upendra, Dumouchel, Jennifer, Dunne, Christine and Andrea, Bushee (2017) Ocular Non-P450 oxidative, hydrolytic and conjugative drug metabolizing enzymes. Drug metabolism reviews. pp. 1-23. ISSN 1097-9883
Argikar, Upendra, Dumouchel, Jennifer, Kramlinger, Valerie, Cirello, Amanda, Gunduz, Mithat, Dunne, Christine and Sohal, Bindi (2017) Do We Need to Study Metabolism and Distribution in the Eye: Why, When, and Are We There Yet? Journal of Pharmaceutical Sciences, 106 (9). pp. 2276-2281. ISSN 15206017
Arias, HR, Jin, Xiaotao, Feuerbach, Dominik and Drenan, RM (2017) Nicotinic acetylcholine receptor selectivity and inhibitory activity on mouse medial habenula by coronaridine congeners. international journal of biochemistry and cell biology, 92. pp. 202-209.
Auberson, Yves (2017) Editorial - In vivo molecular imaging tools facilitates Drug Discovery. Drug Discovery Today: Technologies, 25. pp. 1-2.
Ayalasomayajula, Surya, Pan , Wei , Han , Yi , Yang, Fan, Langenickel, Thomas Heiko, Pal, Parasar, Yao Zong , Yuan and Sunkara, Gangadhar (2017) Assessment of Drug–Drug Interaction Potential Between Atorvastatin and LCZ696, A Novel Angiotensin Receptor Neprilysin Inhibitor, in Healthy Chinese Male Subjects. European Journal of Drug Metabolism and Pharmacokinetics, 42 (2). pp. 309-318. ISSN 21070180
B
Badal Tejedor, Maria, Nordgren, Niklas, Rutland, Mark, Schuleit, Michael, Millqvist-Fureby, Anna, Alderborn, Goran and Pazesh, Samaneh (2017) Determination of Interfacial Amorphicity in Functional Powders. Langmuir the ACS journal of surfaces and colloids., 33 (33). pp. 920-926. ISSN 1520-5827; 0743-7463
Badal Tejedor, Maria, Nordgren, Niklas, Schuleit, Michael, Millqvist-Fureby, Anna and Rutland, Mark (2017) AFM colloidal probe measurements implicate capillary condensation in punch-particle surface interactions during tableting. Langmuir the ACS journal of surfaces and colloids., 33. pp. 13180-13188. ISSN 1520-5827; 0743-7463
Baenziger, Markus, Durantie, Estelle and Mathes, Christian (2017) Development of an Industrial Process Based on the Groebke– Blackburn–Bienaymé Multicomponent Reaction: Efficient Preparation of 3-Aminoimidazo[1,2-a]pyrazines. Synthesis.
Baguia, Hajar (2017) Fluoride-free Hiyama cross-coupling in presence of surfactants and water. Report to be submitted to Université Libre de Bruxelles.
Beckmann, Nicolau (2017) Editorial: In vivo imaging in pharmacological research. Frontiers in Pharmacology, 7 (JAN). pp. 7-511. ISSN 16639812
Bernabei, Roberto, Mariotti, Luca, Brodes, Philippe and Roubenoff, Ronenn (2017) The “Sarcopenia and Physical fRailty IN older people: multi-componenT Treatment strategies” (SPRINTT) project: advancing the care of physically frail and sarcopenic older people. Aging Clinical and Experimental Research, 29 (1). ISSN 17208319
Bialucha, Carl, Collins, Scott, Li, Xiao, Saxena, Parmita, Zhang, Xiamei, Duerr, Clemens, Shim, Yeonju, Mosher, Rebecca, Ostrom, Lance, Hu, Tiancen, Bilic, Sanela, Liric Rajlic, Ivana, Capka, Vladimir, Sharp, Fiona, Antonakos, Brandon, Wagner, Joel, Elliott, Ginell, Veloso, Artur, Piel, Jessica, Xu, Jian, Flaherty, Meghan, Mansfield, Keith, London, Anne, Kurz, Markus, Nguyen, Duc, Meyer, Matthew, Faris, Jason, Janatpour, Mary, Chan, Vivien, Yoder, Nicholas, Catcott, Kelly, McShea, Molly, Sun, Xiuxia, Gao, Hui, Williams, Juliet, Hofmann, Francesco, Engelman, Jeffrey, Ettenberg, Seth, Sellers, William and Lees, Emma (2017) Discovery and optimization of HKT288, a cadherin-6-targeting ADC for the treatment of ovarian and renal cancers. Cancer Discovery, 7 (9). pp. 1030-1045. ISSN 21598290
Bizec, Jean-Claude, Glogovac, Milica, Gromek, Kamila, Prause, Maarten, Winkler, Gian Christian, Milton, Mark, Newton, Ronald and Lovsin Barle, Ester (2017) Determination of Permitted Daily Exposure for Topical Ocular Drugs. Determination of Permitted Daily Exposure for Topical Ocular Drugs (00). pp. 1-9. ISSN 1083-7450
Blanz, Joachim, Dayer, Jerome, Delemonte, Thierry, Gertsch, Werner, Ramstein, Philippe, Williams, Gareth, Aichholz, Reiner, Trunzer, Markus and Pearson, David (2017) Evaluation of relative MS response factors of drug metabolites for semi-quantitative assessment of chemical liabilities in drug discovery. Journal of Mass Spectrometry, 52 (4). pp. 210-217. ISSN 1096-9888
Blasko, Andrei, Rao, Raj, Kuehl, Philip J. , Holmes, Thomas D. , Reed, Matthew D., Xu, Fadi and Zhuang, Jianguo (2017) A Physicochemical Assessment of Acid-induced Post-inhalation Cough in Guinea Pigs Animal Model. American Journal of Advanced Drug Delivery, 5 (4). pp. 131-138. ISSN ISSN 2321-547X
Blasko, Andrei, Tam, Yat Kong and Haidar Ahmad, Imad A. (2017) Cleaning verification dilemma of manufacturing equipment: Can the analytical method validation fail due to the cleanliness of the stainless steel surfaces? Atlas of Science, Octobe.
Blatter, Markus, Krepl, Miroslav , Cléry, Antoine , Allain, Frédéric H.T. and Sponer, Jiri (2017) Structural study of the Fox-1 RRM protein hydration reveal a role for key water molecules in RRM-RNA recognition. Nucleic Acids Research. ISSN 0305-10481362-4962
Brecht, Karin, Riebel, Virginie, Couttet, Philippe, Paech, Franziska, Wolf, Armin, Chibout, Salah-Dine, Pognan, Francois, Krähenbühl, Stephan and Uteng, Marianne (2017) Mechanistic insights into selective killing of OXPHOS-dependent pancreatic cancer cells by arctigenin. Toxicology in vitro, 40. pp. 55-65. ISSN 08872333
Brocklehurst, Cara, Koch, Guido, Makarov, Ilya S., Karaghiosoff, Konstantin L. and Knochel, Paul (2017) Synthesis of Bicyclo[1.1.1]pentane Bioisosteres of Internal Alkynes and para-Disubstituted Benzenes from [1.1.1]Propellane. Angewandte Chemie International Edition.
Brocklehurst, Cara, Rothe-Poellet, Stephanie, Koch, Guido and La Vecchia, Luigi (2017) In Situ Preparation and Consumption of O-Mesitylsulfonylhydroxylamine (MSH) in Continuous Flow for the Amination of Pyridines. Synlett. ISSN 14372096
Brown, Alan, Saravanan, Chandrassegar, Devine, Pj, Magnifico, Maria, Gao, Jiaping, Beaulieu, Valerie, Ma, Margaret, Yasoshima, Kayo, Barnes, David and Yamada, Ken (2017) Characterization of intra-articular dose administration in the stifle joint of rabbits for toxicity testing. International Journal of Toxicology, 36 (4). pp. 303-313. ISSN 1092874X
Bruin, Gerardus, Loesche, Christian, Nyirady, Judit and Sander, Oliver (2017) Population Pharmacokinetic Modeling of Secukinumab in Patients With Moderate to Severe Psoriasis. Journal of Clinical Pharmacology, 57 (7). pp. 876-885. ISSN 1552-4604
Burkhart, Christoph, Kucher, Klaus, Sloth, Birgitte and Huber, Roland (2017) 1st Newsletter for ESID level 3 project in APDS. 1st Newsletter for ESID level 3 project in APDS.
Burks, Heather, Abrams, Tinya, Baird, Jason, Fekete, Alexander, Hamann, Lawrence, Kim, Sunkyu, Kirby, Christina, Lambardo, Franco, Loo, Alice, Lubicka, Danuta, Macchi, Kaitlin, McDonnell, Donald P. , Mishina, Yuji, Norris, John, Nunez, Jill, Saran, Chitra, Sun, Yingchuan, Thomsen, Noel, Wang, Chunrong, Peukert, Stefan and Wang, Jianling (2017) Discovery of an acrylic acid Based Tetrahydroisoquinoline as an Orally Bioavailable Selective Estrogen Receptor Degrader for ERa+ Breast Cancer. Journal of Medicinal Chemistry.
C
Cahill, Katherine , Katz, Howard , Cui, Jing , Lai, Juying , Kazani, Shamsah, Crosby-Thompson, Allison , Garofalo, Denise , Castro, Mario, Jarjour, Nizar , DiMango, Emily , Erzurum, Serpil , Trevor, Jennifer, Shenoy, Kartik , Chinchilli, Vernon, Wechsler, Michael, Laidlaw, Tanya, Boyce, Joshua and Israel, Elliot (2017) KIT inhibition by imatinib in patients with severe refractory asthma. New England Journal of Medicine, 376 (20). pp. 1911-1920. ISSN 15334406
Caicedo, Juan, Cooper, Sam, Heigwer, Florian, Warchal, Scott, Qiu, Peng, Molnar, Csaba, Vasilevich, Aliaksei, Barry, Joseph, Singh, Harmanjit, Kraus, Oren, Wawer, Mathias, Paavolainen, Lassi, Herrmann, Markus, Rohban, Mohammad, Hung, Jane, Hennig, Holger, Concannon, John, Smith, Ian, Singh, Shantanu, Rees, Paul, Horvath, Peter, Linington, Roger and Carpenter, Anne (2017) Data-analysis strategies for image-based cell profiling. Nature Methods, 14 (9). pp. 849-863. ISSN 15487105
Chandra, Abhishek , Qin , Ling, Kneissel, Michaela, Kramer, Ina, Liu, Sherry, Young, Tiffany and Ma, Xiaoyuan (2017) Suppression of Sclerostin Alleviates Radiation-Induced Bone Loss by Protecting Bone-Forming Cells and Their Progenitors Through Distinct Mechanisms. Journal of Bone and Mineral Research, 32 (2). pp. 360-372. ISSN 1523-4681
Chen, Chih-wei, Beyer, Christian, Liu, Jun, Maier, Christiane, Li, Chun, Trinh-Minh, Thuong, Xu, Xiaohan, Cole, Stuart, Hsieh, Mindy Hsieh, Ng, Nicholas, Althage, Alana, Meeusen, Shelly, Pan, Shifeng, Svensson, Eric, Seidel, Martin, Schett, Georg, Gergely, Peter, Harris, Jennifer and Distler , Jorg (2017) Pharmacological inhibition of porcupine induces regression of experimental skin fibrosis by targeting Wnt Signaling. Annals of the Rheumatic Diseases (1-6). pp. 1-6.
Chen, Chih-wei, Beyer, Christian, Liu, Jun, Maier, Christiane, Li, Chun, Trinh-Minh, Thuong, Xu, Xiaohan, Cole, Stuart, Hsieh, Mindy Hsieh, Ng, Nicholas, Althage, Alana, Meeusen, Shelly, Pan, Shifeng, Svensson, Eric, Seidel, Martin, Schett, Georg, Gergely, Peter, Harris, Jennifer and Distler , Jorg (2017) Pharmacological inhibition of porcupine induces regression of experimental skin fibrosis by targeting Wnt signalling. Annals of the Rheumatic Diseases, 76 (4). pp. 773-778. ISSN 1468-2060
Chen, Huaibin, Marsiglia, William M, Cho, Min-Kyu, Huang, Zhifeng, Deng, Jingjing, Blais, Steven P, Gai, Weiming, Bhattacharya, Shibani, Neubert, Thomas A, Traaseth, Nathaniel J and Mohammadi, Moosa (2017) Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases. eLife, 6. ISSN 2050-084X
Chen, Huaibin, Marsiglia, William M, Cho, Min-Kyu, Huang, Zhifeng, Deng, Jingjing, Blais, Steven P, Gai, Weiming, Bhattacharya, Shibani, Neubert, Thomas A, Traaseth, Nathaniel J and Mohammadi, Moosa (2017) Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases. eLife, 6. ISSN 2050-084X
Chen, Jin, Meyers, Charles, Keefe, Debbi, Yu, Jing and Sunkara, Gangadhar (2017) Clinical Pharmacokinetics of Pradigastat, a Novel Diacylglycerol Acyltransferase 1 Inhibitor. Journal of Drug Design and Research.
Chen, Xin, Giraldes, John, Sprague, Elizabeth, Shakya, Subarna, Chen, Zhuoliang, Wang, Kate, Joud-Caldwell, Carol, Mathieu, Simon, Chen, Christine, Straub, Christopher, Duca, Jose, Hurov, Kristen, Yuan, Yanqiu, Shao, Wenlin and Toure, Bakary-Barry (2017) “Addition” and “Subtraction”: Selectivity Design for Type-II Maternal Embryonic Leucine Zipper Kinase Inhibitors. Journal of Medicinal Chemistry, 60. pp. 2155-2161.
Chen, Zhao (2017) Co-clinical quantitative tumor volume imaging in ALK-rearranged NSCLC treated with crizotinib. European Journal of Radiology, 88. pp. 15-20. ISSN 18727727
Cheung, Sheldon T., Miller, Michelle S., Pacoma, Reynand, Roland, Jason, Schumacher, Andrew, Liu, Jian and Hsieh-Wilson, Linda C. (2017) Discovery of a Small-Molecule Modulator of Glycosaminoglycan Sulfation. ACS Chemical Biology, 12 (12). pp. 3126-3133. ISSN 15548937
Chiang, Derek and Villanueva, Augusto (2017) Progress towards molecular patient stratification of hepatocellular carcinoma: Lost in translation? Journal of Hepatology, 67 (5). pp. 893-895. ISSN 16000641
Cho, Young, Liu, Gang, Caferro, Thomas, Shafer, Cynthia, Manning, James, Sendzik, Martin, Shultz, Michael, Chenail, Gregg, Dooley, Julie, Farsidjani, Alireza, Chen, Jinyun, Kulathila, Raviraj, Xie, Xiaoling, Dodd, Stephanie, Gould, Ty, Liang, Guiqing, Heimbach, Tycho, Slocum, Kelly, Pu, Minying, Pagliarini, Raymond and Growney, Joseph (2017) Discovery and Evaluation of Clinical Candidate IDH305, a Brain Penetrant Mutant IDH1 Inhibitor. ACS Medicinal Chemistry Letters, 8 (10). pp. 1116-1121. ISSN 19485875
Clarke, Adrian, Kotoni, Dorina, Dispas, Amandine, Guillarme, Davy, Hubert, Philippe, Desfontaine, Vincent and Lebrun, Pierre (2017) Quantitative determination of salbutamol sulfate impurities using achiral supercritical fluid chromatography. Journal of Pharmaceutical and Biomedical Analysis, 134. pp. 170-180.
Clottu, A, Mathias, A, Sailer, Andreas, Schluep, M, Seebach, J, Du Pasquier, R and Pot, Caroline (2017) EBI2 expression and function: robust in memory lymphocytes and increased by natalizumab in multiple sclerosis. Cell Reports, 18 (1). pp. 213-224.
Cowell, Annie, LaMonte, Greeg, Abraham, Matthew, Flannery, Erika, William, Roy, Sasaki, Erica, Corey, Victoria, Lukens, Amanda, Istvan, Eva, Lee, Marcus, Franco, Virginia, Reimer, Christin, Magistrado, Pamela, Coburn-Flynn, Olivia, Sakata-Kato, Tomoyo, Bopp, Selina, Gupta, Purva, Fuchs, Olivia, Kim, Sang, Teng, Christine, Gnadig, Nina, Vanaerschot, Manu, Murithi, James, Linares, Maria, Cozar, Cristina, Gomez-Lorenzo, Maria, Prats, Sara, Arriaga, Ignacio, Wang, Lawrence, Ottilie, Sabine, Siegel, Dionicio, Tanaseichuk, Olga, Zhong, Yang, Zhou, Yingyao, Willis, Paul, Gamo, Francisco-Javier, Goldberg, Daniel, Fidock, David, Wirth, Dyann and Winzeler, Elizabeth (2017) Mapping the malaria parasite drug-able genome using in vitro evolution and chemogenomics. Science.
Cox, Georgina, Sieron, Arthur, King, Andrew , De Pascale, Gianfranco, Pawlowski, Andrew, Koteva, Kalinka and Wright, Gerard (2017) A Common Platform for Antibiotic Dereplication and Adjuvant Discovery. Cell chemical biology, 24. pp. 98-109. ISSN 2451-9456
Cramer, Christopher J, Johnson, Joshua and Kamel, Amin (2017) Prediction of Mass Spectral Response Factors from Predicted Chemometric Data for Druglike Molecules. Journal of the American Society for Mass Spectrometry, 28 (2). pp. 278-285. ISSN 1879-1123
Cruz, Leilani, Heidt, Analeah and Rowell, Emily (2017) Postdoc fellowship application for the Damon Runyon Cancer Research Fellowship entitled "Identifying novel pathways responsible for epigenetic modifications in aged regulatory T cells in the tumor microenvironment". Damon Runyon Cancer Research Fellowship.
Cruz, Leilani, Rowell, Emily and Heidt, Analeah (2017) Identification and targeting of novel pathways modifying the epigenome of aged regulatory T cells in the tumor microenvironment. Damon Runyon Cancer Research Fellowship.
Cunha, Andre, Zhang, Qin, Prentiss, Melissa, Wu, Xiaoqiu, Kainz, Vanessa, Xu, Yongyao, Vrouvlianis, Joanna, Li, Hui, Rangaswamy, Nalini, Leehy, Barrett, Mcgee, Terri, Bell, Christie, Bigelow, Chad, Kansara, Viralbhai, Huang, Qian and Wu, Henry (2017) The hierarchy of pro-inflammatory cytokines in ocular inflammation. Current eye research. pp. 1-13. ISSN 1460-2202
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Dafflon, Caroline, Craig, Vanessa, Mereau, Helene, Gräsel, Julius, Schacher Engstler, Barbara, Hoffman, Gregory, Nigsch, Florian, Gaulis, Swann, Barys, Louise, Ito, Moriko, Aguadé Gorgorio, Julia, Bornhauser, Beat, Bourquin, Jean-Pierre, Proske, Amelie, Stork-Fux, Caroline, Murakami, Masato, Sellers, William, Hofmann, Francesco, Schwaller, Jürg and Tiedt, Ralph (2017) Complementary activities of DOT1L and Menin inhibitors in MLL-rearranged leukemia. Leukemia. ISSN 14765551
Dafflon, Caroline, Tiedt, Ralph and Schwaller, Jürg (2017) Targeting multiple nodes of MLL complexes to improve leukemia therapy. Oncotarget, 8 (53). pp. 90614-90615. ISSN 19492553
Dai, Chenkai, Lehar, Mohamed, Sun, Daniel, Swarthout, Lani, Carey, John, Maclachlan, Timothy, Brough, Doug, Staecker, Hinrich, Della Santina, Alexandra, Hullar, Timothy and Della Santina, Charles (2017) Rhesus Cochlear and Vestibular Functions Are Preserved After Inner Ear Injection of Saline Volume Sufficient for Gene Therapy Delivery. JARO - Journal of the Association for Research in Otolaryngology, 18 (4). pp. 601-617. ISSN 1438-7573
Dalvit, Claudio, Piotto, Martial and Vulpetti, Anna (2017) Fluorine NMR spectroscopy and computational calculations for assessing intramolecular hydrogen bond involving fluorine and for characterizing the dynamic of a fluorinated molecule. Journal of fluorine chemistry, 202. pp. 34-40. ISSN 00221139
Das, Suman, Morvan, Frederic, Jourde, Benjamin, Minetti, Giulia, Brebbia, Pascale, Toussaint, Gauthier, Glass, David and Fornaro, Mara (2017) ATP Citrate Lyase regulates myofiber differentiation by altering histone acetylation. Cell reports, 21 (11). pp. 3003-3011. ISSN 22111247
Das, Suman, Morvan, Frederic, Morozzi, Giulio, Jourde, Benjamin, Minetti, Giulia, Kahle, Peter, Rivet, Helene, Brebbia, Pascale, Toussaint, Gauthier, Glass, David and Fornaro, Mara (2017) ATP Citrate Lyase Regulates Myofiber Differentiation and Increases Regeneration by Altering Histone Acetylation. Cell reports, 21 (11). pp. 3003-3011. ISSN 2211-1247
Daugvilaite, Viktorija, Madsen, Christian Medom, Lückmann, Michael, Echeverria, Clara Castello, Sailer, Andreas, Frimurer, Thomas Michael, Rosenkilde, Mette Marie and Benned-Jensen, Tau (2017) Biased signaling and allosteric modulation of G protein-coupled receptor 183 - a 7TM receptor also known as Epstein-Barr virus -induced gene 2. British journal of pharmacology. ISSN 1476-5381; 0007-1188
Davis, John, Kagan, Mark, Read, Jessica, Walles, Markus and Hatsis, Panagiotis (2017) Immunoprecipitation LC-MS Middle-up Approach for In Vivo Drug-To-Antibody Ratio Determination for Antibody Drug Conjugates. Bioanalysis.
Decker, Rebekah (2017) Articular cartilage and joint development from embryogenesis to adulthood. Seminars in cell & developmental biology, 62. pp. 50-56. ISSN 1096-3634
Decker, Rebekah, Um, Hyo-Bin, Dyment, Nathaniel A., Cottingham, Naiga, Usami, Yu, Enomoto-Iwamoto, Motomi, Kronenberg, Mark S., Maye, Peter, Rowe, David W., Koyama, Eiki and Pacifici, Maurizio (2017) Cell origin, volume and arrangement are drivers of articular cartilage formation, morphogenesis and response to injury in mouse limbs. Developmental biology, 426 (1). pp. 56-68. ISSN 00121606
Defontis, Myriam, Cote, Serge and Ledieu, David (2017) A combined approach to early detect in vitro drug-induced hemostatic changes in preclinical safety. Experimental and Toxicologic Pathology. ISSN 1618-1433
Del Signore, Susanna and Roubenoff, Ronenn (2017) Physical frailty and sarcopenia (PF&S): a point of view from the industry. Aging Clinical and Experimental Research, Epub a. pp. 1-6. ISSN 17208319
Dex, Sarah, Alberton, Paolo, Willkomm, Lena, Soellradl, Thomas, Bago, Sandra, Milz, Stefan, Shakibaei, Mehdi, Ignatius, Anita, Bloch, Wilhelm, Clausen-Schaumann, Hauke, Shukunami, China, Schieker, Matthias and Docheva, Denitsa (2017) Tenomodulin is Required for Tendon Endurance Running and Collagen I Fibril Adaptation to Mechanical Load. EBioMedicine, 20. pp. 240-254. ISSN 2352-3964
Dickson, Callum, Hornak, Viktor, Pearlstein, Robert and Duca, Jose (2017) Structure-kinetic relationships of passive membrane permeation from multiscale modeling. Journal of the American Chemical Society JACS., 139 (1). pp. 442-452.
Dickson, Callum, Pearlstein, Robert and Hornak, Viktor (2017) Contributions of the membrane dipole potential to the function of voltage-gated cation channels and modulation by small molecule potentiators. Biochimica et biophysica acta (BBA) - Biomembranes, 1859 (2). pp. 177-194. ISSN 00052736
Dumouchel, Jennifer, Argikar, Upendra, Spear, Jaimie, Brown, Ann, Dunne, Christine, Kramlinger, Valerie, Cirello, Amanda and Gunduz, Mithat (2017) An in vitro Investigation of Ocular Bioactivation Potential and the Role of CytochromeP450 2D Enzymes in Rat. Drug metabolism letters.. ISSN 1874-0758
Dégardin, Klara, Desponds, Anne and Roggo, Yves (2017) Protein-based medicines analysis by Raman spectroscopy for the detection of counterfeits. Forensic Science International, 278. pp. 313-325. ISSN 03790738
Dégardin, Klara and Roggo, Yves (2017) Innovative Strategy for Counterfeit Analysis. Medicine Access @ Point of Care, 1 (1). maapoc.0000013. ISSN 2399-2026
de Moura França, Leandro , Amigo, José Manuel , Cairós, Carlos , Bautista Mercader, Manuel and Fernanda Pimentel, Maria (2017) Evaluation and assessment of homogeneity in images. Part 1: Unique homogeneity percentage for binary images. Chemometrics and Intelligent Laboratory Systems, 171. pp. 26-39. ISSN 0169-7439
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Ebata, Kevin T., Mesh, Kathryn, Liu, Shichong, Bilenky, Misha, Fekete, Alexander, Acker, Michael, Hirst, Martin, Garcia, Benjamin A and Ramalho-Santos, Miguel (2017) Vitamin C Induces Specific Demethylation of H3K9me2 in Mouse Embryonic Stem Cells via Kdm3a/b. Epigenetics & chromatin, 10. p. 36. ISSN 1756-8935
Ebhardt, H. Alexander, Degen, Simone, Tadini, Valentina, Schilb, Alain, Greig, Carolyn A., Fearon, Kenneth CH, Aebersold, Ruedi and Jacobi, Carsten (2017) Comprehensive proteome analysis of muscle composition and development in seniors. EMBO Molecular Medicine.
Eder, Joerg (2017) Opportunities and challenges in phenotypic drug discovery: An industry perspective. Nature Reviews Drug Discovery, 16 (8). pp. 531-543. ISSN 14741784
Edge, Stephen, Singh, Dilraj, Lewis, David and Rouse, Tim (2017) Defining the “Dose” for Dry Powder Inhalers: The challenge of correlating in-vitro dose delivery results with clinical efficacy. American pharmaceutical review, 20 (3). pp. 54-62.
Egger, Christine, Cannet, Catherine, Gerard Sachot, Christelle, Pierrat, Benoit, Suply, Thomas, Ksiazek, Iwona and Beckmann, Nicolau (2017) Effects of the fibroblast activation protein inhibitor, PT100, in a murine model of pulmonary fibrosis. European Journal of Pharmacology, 809. pp. 64-72. ISSN 18790712
Einolf, Heidi, Lin, Wen, Wang, Lai, Gu, Helen, Chun, Dung Y., Mangold, James B. and He, Handan (2017) Physiologically-based pharmacokinetic model predictions of panobinostat (LBH589) as a victim and perpetrator of drug-drug interactions. Drug Metabolism and Disposition.
Einolf, Heidi, Zhou, Jocelyn, Won, Christina, Wang, Lai and Rebello, Sam (2017) A physiologically-based pharmacokinetic modeling approach to predict drug-drug interactions of sonidegib (LDE225) with perpetrators of CYP3A in cancer patients. Drug metabolism and disposition, 45 (4). pp. 361-374. ISSN 1521-009X
Emery, Caroline, Monaco, Kelli-Ann, Wang, Ping, Balak, Marissa, Freeman, Alyson, Meltzer, Jodi, Delach, Scott, Rakiec, Daniel, Ruddy, David, Korn, Joshua, Haling, Jake, Acker, Michael and Caponigro, Giordano (2017) BRAF-inhibitor associated MEK mutations increase RAF-dependent and -independent enzymatic activity. Molecular Cancer Research, 15 (10). pp. 1431-1444. ISSN 1557-3125
Ertl, Peter (2017) An algorithm to identify functional groups in organic molecules. Journal of cheminformatics, 9 (1). p. 36. ISSN 1758-2946
Ertl, Peter, Lewis, Richard, Martin, Eric and Polyakov, Valery (2017) In silico generation of novel, drug-like chemical matter using the LSTM neural network. arXiv / talk at CCG User Group Meeting.
Estoppey, David, Hewett, Jeffrey, Guy, Chantale, Harrington, Edmund, Thomas, Jason, Schirle, Markus, Cuttat-Theurillat, Rachel, Waldt, Annick, Gerrits, Bertran, Yang, Zinger, Schuierer, Sven, Carbone, Walter, Knehr, Judith, Lindeman, Alicia, Russ, Carsten, Frias, Elizabeth, Hoffman, Gregory, Varadarajan, Malini, Ramadan, Nadire, Reece-Hoyes, John, Wang, Qiong, Chen, Xin, Mcallister, Gregory, Roma, Guglielmo, Bouwmeester, Antonius and Hoepfner, Dominic (2017) Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells. Scientific reports, 7 (42728). pp. 1-6. ISSN 2045-2322
Estoppey, David, Lee, Chia Min, Janoschke, Marco, Mathys, Philippe, Filipuzzi, Ireos, Schuhmann, Tim, Riedl, Ralph, Aust, Thomas, Galuba, Olaf, Mcallister, Gregory, Russ, Carsten, Spiess, Martin, Bouwmeester, Antonius, Bonamy, Ghislain and Hoepfner, Dominic (2017) The Natural Product Cavinafungin Selectively Interferes with Zika and Dengue Virus Replication by Inhibition of the Host Signal Peptidase. Cell Reports, 19 (3). pp. 451-460. ISSN 22111247
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Fairfield, Heather, Falank, Carolyne, Harris, Elizabeth, Demambro, Victoria, McDonald, Michelle, Pettitt, Jessica A., Mohanty, Sindhu T., Croucher, Peter, Kramer, Ina, Kneissel, Michaela, Rosen, Clifford J. and Reagan, Michaela R. (2017) The skeletal cell-derived molecule sclerostin drives bone marrow adipogenesis. Journal of cellular physiology.
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