A

Abraham, Yann, Gerrits, Bertran, Rebhan, Michael, Ludwig, Marie-Gabrielle and Gubser Keller, Caroline (2017) Exploring Glucocorticoid Receptor Agonists Mechanism of Action Through Mass Cytometry and Radial Visualizations. Cytometry. Part B : clinical cytometry., 92 (1). pp. 42-56. ISSN 1552-4957; 1552-4949

Altmann, Eva, Erbel, Paulus, Renatus, Martin, Schaefer, Michael, Schlierf, Anita, Druet, Adelaide, Kieffer, Laurence, Sorge, Mickael, Pfister, Keith, Hassiepen, Ulrich, Ostermeier, Daniela, Martoglio, Bruno, Jefferson , Anne B. and Ruedisser, Simon (2017) Azaindoles as Zinc-Binding Small-Molecule Inhibitors of the JAMM Protease CSN5. Chimia., 71 (4). p. 241. ISSN 10.2533/chimia2017.241

Altmann, Eva, Schlierf, Anita, Schaefer, Michael, Renatus, Martin, Ruedisser, Simon, Erbel, Paulus, Ostermeier, Daniela, Druet, Adelaide, Kieffer, Laurence, Sorge, Mickael, Hassiepen, Ulrich, Jones, Matthew, Pfister, Keith, Jefferson, Ann, Martoglio, Bruno and Quancard, Jean (2017) Azaindoles as zinc-binding small molecule inhibitors of the JAMM protease CSN5. Angewandte Chemie, 56 (5). pp. 1294-1297. ISSN 1433-7851

Ambrose, Jessi, Mapa, Felipa, Ross, Nathan, Chen, Julie, Ye, Chaoyang and Bilican, Bilada (2017) Automated Scale-up and Maintenance of Stem Cell-Induced Neurons for Long-Term Culture and High-Throughput Screening. SLAS Technology.

Amsler, Philipp, Heudi, Olivier, Lanshoeft, Christian, Bettighofer, Anja, Eisfeld, Jochen, Moenius, Thomas, Probst, Claudia Monika and Etter, Coralie (2017) Production and application of high quality stable isotope labeled monoclonal antibody for mass spectrometry analysis. Journal of labelled compounds and radiopharmaceuticals. ISSN 03624803

Argikar, Upendra, Dumouchel, Jennifer, Dunne, Christine and Andrea, Bushee (2017) Ocular Non-P450 oxidative, hydrolytic and conjugative drug metabolizing enzymes. Drug metabolism reviews. pp. 1-23. ISSN 1097-9883

Argikar, Upendra, Dumouchel, Jennifer, Kramlinger, Valerie, Cirello, Amanda, Gunduz, Mithat, Dunne, Christine and Sohal, Bindi (2017) Do We Need to Study Metabolism and Distribution in the Eye: Why, When, and Are We There Yet? Journal of Pharmaceutical Sciences, 106 (9). pp. 2276-2281. ISSN 15206017

Arias, HR, Jin, Xiaotao, Feuerbach, Dominik and Drenan, RM (2017) Nicotinic acetylcholine receptor selectivity and inhibitory activity on mouse medial habenula by coronaridine congeners. international journal of biochemistry and cell biology, 92. pp. 202-209.

Auberson, Yves (2017) Editorial - In vivo molecular imaging tools facilitates Drug Discovery. Drug Discovery Today: Technologies, 25. pp. 1-2.

Ayalasomayajula, Surya, Pan , Wei , Han , Yi , Yang, Fan, Langenickel, Thomas Heiko, Pal, Parasar, Yao Zong , Yuan and Sunkara, Gangadhar (2017) Assessment of Drug–Drug Interaction Potential Between Atorvastatin and LCZ696, A Novel Angiotensin Receptor Neprilysin Inhibitor, in Healthy Chinese Male Subjects. European Journal of Drug Metabolism and Pharmacokinetics, 42 (2). pp. 309-318. ISSN 21070180

B

Badal Tejedor, Maria, Nordgren, Niklas, Rutland, Mark, Schuleit, Michael, Millqvist-Fureby, Anna, Alderborn, Goran and Pazesh, Samaneh (2017) Determination of Interfacial Amorphicity in Functional Powders. Langmuir the ACS journal of surfaces and colloids., 33 (33). pp. 920-926. ISSN 1520-5827; 0743-7463

Badal Tejedor, Maria, Nordgren, Niklas, Schuleit, Michael, Millqvist-Fureby, Anna and Rutland, Mark (2017) AFM colloidal probe measurements implicate capillary condensation in punch-particle surface interactions during tableting. Langmuir the ACS journal of surfaces and colloids., 33. pp. 13180-13188. ISSN 1520-5827; 0743-7463

Baenziger, Markus, Durantie, Estelle and Mathes, Christian (2017) Development of an Industrial Process Based on the Groebke– Blackburn–Bienaymé Multicomponent Reaction: Efficient Preparation of 3-Aminoimidazo[1,2-a]pyrazines. Synthesis.

Baguia, Hajar (2017) Fluoride-free Hiyama cross-coupling in presence of surfactants and water. Report to be submitted to Université Libre de Bruxelles.

Beckmann, Nicolau (2017) Editorial: In vivo imaging in pharmacological research. Frontiers in Pharmacology, 7 (JAN). pp. 7-511. ISSN 16639812

Bernabei, Roberto, Mariotti, Luca, Brodes, Philippe and Roubenoff, Ronenn (2017) The “Sarcopenia and Physical fRailty IN older people: multi-componenT Treatment strategies” (SPRINTT) project: advancing the care of physically frail and sarcopenic older people. Aging Clinical and Experimental Research, 29 (1). ISSN 17208319

Bialucha, Carl, Collins, Scott, Li, Xiao, Saxena, Parmita, Zhang, Xiamei, Duerr, Clemens, Shim, Yeonju, Mosher, Rebecca, Ostrom, Lance, Hu, Tiancen, Bilic, Sanela, Liric Rajlic, Ivana, Capka, Vladimir, Sharp, Fiona, Antonakos, Brandon, Wagner, Joel, Elliott, Ginell, Veloso, Artur, Piel, Jessica, Xu, Jian, Flaherty, Meghan, Mansfield, Keith, London, Anne, Kurz, Markus, Nguyen, Duc, Meyer, Matthew, Faris, Jason, Janatpour, Mary, Chan, Vivien, Yoder, Nicholas, Catcott, Kelly, McShea, Molly, Sun, Xiuxia, Gao, Hui, Williams, Juliet, Hofmann, Francesco, Engelman, Jeffrey, Ettenberg, Seth, Sellers, William and Lees, Emma (2017) Discovery and optimization of HKT288, a cadherin-6-targeting ADC for the treatment of ovarian and renal cancers. Cancer Discovery, 7 (9). pp. 1030-1045. ISSN 21598290

Bizec, Jean-Claude, Glogovac, Milica, Gromek, Kamila, Prause, Maarten, Winkler, Gian Christian, Milton, Mark, Newton, Ronald and Lovsin Barle, Ester (2017) Determination of Permitted Daily Exposure for Topical Ocular Drugs. Determination of Permitted Daily Exposure for Topical Ocular Drugs (00). pp. 1-9. ISSN 1083-7450

Blanz, Joachim, Dayer, Jerome, Delemonte, Thierry, Gertsch, Werner, Ramstein, Philippe, Williams, Gareth, Aichholz, Reiner, Trunzer, Markus and Pearson, David (2017) Evaluation of relative MS response factors of drug metabolites for semi-quantitative assessment of chemical liabilities in drug discovery. Journal of Mass Spectrometry, 52 (4). pp. 210-217. ISSN 1096-9888

Blasko, Andrei, Rao, Raj, Kuehl, Philip J. , Holmes, Thomas D. , Reed, Matthew D., Xu, Fadi and Zhuang, Jianguo (2017) A Physicochemical Assessment of Acid-induced Post-inhalation Cough in Guinea Pigs Animal Model. American Journal of Advanced Drug Delivery, 5 (4). pp. 131-138. ISSN ISSN 2321-547X

Blasko, Andrei, Tam, Yat Kong and Haidar Ahmad, Imad A. (2017) Cleaning verification dilemma of manufacturing equipment: Can the analytical method validation fail due to the cleanliness of the stainless steel surfaces? Atlas of Science, Octobe.

Blatter, Markus, Krepl, Miroslav , Cléry, Antoine , Allain, Frédéric H.T. and Sponer, Jiri (2017) Structural study of the Fox-1 RRM protein hydration reveal a role for key water molecules in RRM-RNA recognition. Nucleic Acids Research. ISSN 0305-10481362-4962

Brecht, Karin, Riebel, Virginie, Couttet, Philippe, Paech, Franziska, Wolf, Armin, Chibout, Salah-Dine, Pognan, Francois, Krähenbühl, Stephan and Uteng, Marianne (2017) Mechanistic insights into selective killing of OXPHOS-dependent pancreatic cancer cells by arctigenin. Toxicology in vitro, 40. pp. 55-65. ISSN 08872333

Brocklehurst, Cara, Koch, Guido, Makarov, Ilya S., Karaghiosoff, Konstantin L. and Knochel, Paul (2017) Synthesis of Bicyclo[1.1.1]pentane Bioisosteres of Internal Alkynes and para-Disubstituted Benzenes from [1.1.1]Propellane. Angewandte Chemie International Edition.

Brocklehurst, Cara, Rothe-Poellet, Stephanie, Koch, Guido and La Vecchia, Luigi (2017) In Situ Preparation and Consumption of O-Mesitylsulfonylhydroxylamine (MSH) in Continuous Flow for the Amination of Pyridines. Synlett. ISSN 14372096

Brown, Alan, Saravanan, Chandrassegar, Devine, Pj, Magnifico, Maria, Gao, Jiaping, Beaulieu, Valerie, Ma, Margaret, Yasoshima, Kayo, Barnes, David and Yamada, Ken (2017) Characterization of intra-articular dose administration in the stifle joint of rabbits for toxicity testing. International Journal of Toxicology, 36 (4). pp. 303-313. ISSN 1092874X

Bruin, Gerardus, Loesche, Christian, Nyirady, Judit and Sander, Oliver (2017) Population Pharmacokinetic Modeling of Secukinumab in Patients With Moderate to Severe Psoriasis. Journal of Clinical Pharmacology, 57 (7). pp. 876-885. ISSN 1552-4604

Burkhart, Christoph, Kucher, Klaus, Sloth, Birgitte and Huber, Roland (2017) 1st Newsletter for ESID level 3 project in APDS. 1st Newsletter for ESID level 3 project in APDS.

Burks, Heather, Abrams, Tinya, Baird, Jason, Fekete, Alexander, Hamann, Lawrence, Kim, Sunkyu, Kirby, Christina, Lambardo, Franco, Loo, Alice, Lubicka, Danuta, Macchi, Kaitlin, McDonnell, Donald P. , Mishina, Yuji, Norris, John, Nunez, Jill, Saran, Chitra, Sun, Yingchuan, Thomsen, Noel, Wang, Chunrong, Peukert, Stefan and Wang, Jianling (2017) Discovery of an acrylic acid Based Tetrahydroisoquinoline as an Orally Bioavailable Selective Estrogen Receptor Degrader for ERa+ Breast Cancer. Journal of Medicinal Chemistry.

C

Cahill, Katherine , Katz, Howard , Cui, Jing , Lai, Juying , Kazani, Shamsah, Crosby-Thompson, Allison , Garofalo, Denise , Castro, Mario, Jarjour, Nizar , DiMango, Emily , Erzurum, Serpil , Trevor, Jennifer, Shenoy, Kartik , Chinchilli, Vernon, Wechsler, Michael, Laidlaw, Tanya, Boyce, Joshua and Israel, Elliot (2017) KIT inhibition by imatinib in patients with severe refractory asthma. New England Journal of Medicine, 376 (20). pp. 1911-1920. ISSN 15334406

Caicedo, Juan, Cooper, Sam, Heigwer, Florian, Warchal, Scott, Qiu, Peng, Molnar, Csaba, Vasilevich, Aliaksei, Barry, Joseph, Singh, Harmanjit, Kraus, Oren, Wawer, Mathias, Paavolainen, Lassi, Herrmann, Markus, Rohban, Mohammad, Hung, Jane, Hennig, Holger, Concannon, John, Smith, Ian, Singh, Shantanu, Rees, Paul, Horvath, Peter, Linington, Roger and Carpenter, Anne (2017) Data-analysis strategies for image-based cell profiling. Nature Methods, 14 (9). pp. 849-863. ISSN 15487105

Chandra, Abhishek , Qin , Ling, Kneissel, Michaela, Kramer, Ina, Liu, Sherry, Young, Tiffany and Ma, Xiaoyuan (2017) Suppression of Sclerostin Alleviates Radiation-Induced Bone Loss by Protecting Bone-Forming Cells and Their Progenitors Through Distinct Mechanisms. Journal of Bone and Mineral Research, 32 (2). pp. 360-372. ISSN 1523-4681

Chen, Chih-wei, Beyer, Christian, Liu, Jun, Maier, Christiane, Li, Chun, Trinh-Minh, Thuong, Xu, Xiaohan, Cole, Stuart, Hsieh, Mindy Hsieh, Ng, Nicholas, Althage, Alana, Meeusen, Shelly, Pan, Shifeng, Svensson, Eric, Seidel, Martin, Schett, Georg, Gergely, Peter, Harris, Jennifer and Distler , Jorg (2017) Pharmacological inhibition of porcupine induces regression of experimental skin fibrosis by targeting Wnt Signaling. Annals of the Rheumatic Diseases (1-6). pp. 1-6.

Chen, Chih-wei, Beyer, Christian, Liu, Jun, Maier, Christiane, Li, Chun, Trinh-Minh, Thuong, Xu, Xiaohan, Cole, Stuart, Hsieh, Mindy Hsieh, Ng, Nicholas, Althage, Alana, Meeusen, Shelly, Pan, Shifeng, Svensson, Eric, Seidel, Martin, Schett, Georg, Gergely, Peter, Harris, Jennifer and Distler , Jorg (2017) Pharmacological inhibition of porcupine induces regression of experimental skin fibrosis by targeting Wnt signalling. Annals of the Rheumatic Diseases, 76 (4). pp. 773-778. ISSN 1468-2060

Chen, Huaibin, Marsiglia, William M, Cho, Min-Kyu, Huang, Zhifeng, Deng, Jingjing, Blais, Steven P, Gai, Weiming, Bhattacharya, Shibani, Neubert, Thomas A, Traaseth, Nathaniel J and Mohammadi, Moosa (2017) Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases. eLife, 6. ISSN 2050-084X

Chen, Huaibin, Marsiglia, William M, Cho, Min-Kyu, Huang, Zhifeng, Deng, Jingjing, Blais, Steven P, Gai, Weiming, Bhattacharya, Shibani, Neubert, Thomas A, Traaseth, Nathaniel J and Mohammadi, Moosa (2017) Elucidation of a four-site allosteric network in fibroblast growth factor receptor tyrosine kinases. eLife, 6. ISSN 2050-084X

Chen, Jin, Meyers, Charles, Keefe, Debbi, Yu, Jing and Sunkara, Gangadhar (2017) Clinical Pharmacokinetics of Pradigastat, a Novel Diacylglycerol Acyltransferase 1 Inhibitor. Journal of Drug Design and Research.

Chen, Xin, Giraldes, John, Sprague, Elizabeth, Shakya, Subarna, Chen, Zhuoliang, Wang, Kate, Joud-Caldwell, Carol, Mathieu, Simon, Chen, Christine, Straub, Christopher, Duca, Jose, Hurov, Kristen, Yuan, Yanqiu, Shao, Wenlin and Toure, Bakary-Barry (2017) “Addition” and “Subtraction”: Selectivity Design for Type-II Maternal Embryonic Leucine Zipper Kinase Inhibitors. Journal of Medicinal Chemistry, 60. pp. 2155-2161.

Chen, Zhao (2017) Co-clinical quantitative tumor volume imaging in ALK-rearranged NSCLC treated with crizotinib. European Journal of Radiology, 88. pp. 15-20. ISSN 18727727

Cheung, Sheldon T., Miller, Michelle S., Pacoma, Reynand, Roland, Jason, Schumacher, Andrew, Liu, Jian and Hsieh-Wilson, Linda C. (2017) Discovery of a Small-Molecule Modulator of Glycosaminoglycan Sulfation. ACS Chemical Biology, 12 (12). pp. 3126-3133. ISSN 15548937

Chiang, Derek and Villanueva, Augusto (2017) Progress towards molecular patient stratification of hepatocellular carcinoma: Lost in translation? Journal of Hepatology, 67 (5). pp. 893-895. ISSN 16000641

Cho, Young, Liu, Gang, Caferro, Thomas, Shafer, Cynthia, Manning, James, Sendzik, Martin, Shultz, Michael, Chenail, Gregg, Dooley, Julie, Farsidjani, Alireza, Chen, Jinyun, Kulathila, Raviraj, Xie, Xiaoling, Dodd, Stephanie, Gould, Ty, Liang, Guiqing, Heimbach, Tycho, Slocum, Kelly, Pu, Minying, Pagliarini, Raymond and Growney, Joseph (2017) Discovery and Evaluation of Clinical Candidate IDH305, a Brain Penetrant Mutant IDH1 Inhibitor. ACS Medicinal Chemistry Letters, 8 (10). pp. 1116-1121. ISSN 19485875

Clarke, Adrian, Kotoni, Dorina, Dispas, Amandine, Guillarme, Davy, Hubert, Philippe, Desfontaine, Vincent and Lebrun, Pierre (2017) Quantitative determination of salbutamol sulfate impurities using achiral supercritical fluid chromatography. Journal of Pharmaceutical and Biomedical Analysis, 134. pp. 170-180.

Clottu, A, Mathias, A, Sailer, Andreas, Schluep, M, Seebach, J, Du Pasquier, R and Pot, Caroline (2017) EBI2 expression and function: robust in memory lymphocytes and increased by natalizumab in multiple sclerosis. Cell Reports, 18 (1). pp. 213-224.

Cowell, Annie, LaMonte, Greeg, Abraham, Matthew, Flannery, Erika, William, Roy, Sasaki, Erica, Corey, Victoria, Lukens, Amanda, Istvan, Eva, Lee, Marcus, Franco, Virginia, Reimer, Christin, Magistrado, Pamela, Coburn-Flynn, Olivia, Sakata-Kato, Tomoyo, Bopp, Selina, Gupta, Purva, Fuchs, Olivia, Kim, Sang, Teng, Christine, Gnadig, Nina, Vanaerschot, Manu, Murithi, James, Linares, Maria, Cozar, Cristina, Gomez-Lorenzo, Maria, Prats, Sara, Arriaga, Ignacio, Wang, Lawrence, Ottilie, Sabine, Siegel, Dionicio, Tanaseichuk, Olga, Zhong, Yang, Zhou, Yingyao, Willis, Paul, Gamo, Francisco-Javier, Goldberg, Daniel, Fidock, David, Wirth, Dyann and Winzeler, Elizabeth (2017) Mapping the malaria parasite drug-able genome using in vitro evolution and chemogenomics. Science.

Cox, Georgina, Sieron, Arthur, King, Andrew , De Pascale, Gianfranco, Pawlowski, Andrew, Koteva, Kalinka and Wright, Gerard (2017) A Common Platform for Antibiotic Dereplication and Adjuvant Discovery. Cell chemical biology, 24. pp. 98-109. ISSN 2451-9456

Cramer, Christopher J, Johnson, Joshua and Kamel, Amin (2017) Prediction of Mass Spectral Response Factors from Predicted Chemometric Data for Druglike Molecules. Journal of the American Society for Mass Spectrometry, 28 (2). pp. 278-285. ISSN 1879-1123

Cruz, Leilani, Heidt, Analeah and Rowell, Emily (2017) Postdoc fellowship application for the Damon Runyon Cancer Research Fellowship entitled "Identifying novel pathways responsible for epigenetic modifications in aged regulatory T cells in the tumor microenvironment". Damon Runyon Cancer Research Fellowship.

Cruz, Leilani, Rowell, Emily and Heidt, Analeah (2017) Identification and targeting of novel pathways modifying the epigenome of aged regulatory T cells in the tumor microenvironment. Damon Runyon Cancer Research Fellowship.

Cunha, Andre, Zhang, Qin, Prentiss, Melissa, Wu, Xiaoqiu, Kainz, Vanessa, Xu, Yongyao, Vrouvlianis, Joanna, Li, Hui, Rangaswamy, Nalini, Leehy, Barrett, Mcgee, Terri, Bell, Christie, Bigelow, Chad, Kansara, Viralbhai, Huang, Qian and Wu, Henry (2017) The hierarchy of pro-inflammatory cytokines in ocular inflammation. Current eye research. pp. 1-13. ISSN 1460-2202

D

Dafflon, Caroline, Craig, Vanessa, Mereau, Helene, Gräsel, Julius, Schacher Engstler, Barbara, Hoffman, Gregory, Nigsch, Florian, Gaulis, Swann, Barys, Louise, Ito, Moriko, Aguadé Gorgorio, Julia, Bornhauser, Beat, Bourquin, Jean-Pierre, Proske, Amelie, Stork-Fux, Caroline, Murakami, Masato, Sellers, William, Hofmann, Francesco, Schwaller, Jürg and Tiedt, Ralph (2017) Complementary activities of DOT1L and Menin inhibitors in MLL-rearranged leukemia. Leukemia. ISSN 14765551

Dafflon, Caroline, Tiedt, Ralph and Schwaller, Jürg (2017) Targeting multiple nodes of MLL complexes to improve leukemia therapy. Oncotarget, 8 (53). pp. 90614-90615. ISSN 19492553

Dai, Chenkai, Lehar, Mohamed, Sun, Daniel, Swarthout, Lani, Carey, John, Maclachlan, Timothy, Brough, Doug, Staecker, Hinrich, Della Santina, Alexandra, Hullar, Timothy and Della Santina, Charles (2017) Rhesus Cochlear and Vestibular Functions Are Preserved After Inner Ear Injection of Saline Volume Sufficient for Gene Therapy Delivery. JARO - Journal of the Association for Research in Otolaryngology, 18 (4). pp. 601-617. ISSN 1438-7573

Dalvit, Claudio, Piotto, Martial and Vulpetti, Anna (2017) Fluorine NMR spectroscopy and computational calculations for assessing intramolecular hydrogen bond involving fluorine and for characterizing the dynamic of a fluorinated molecule. Journal of fluorine chemistry, 202. pp. 34-40. ISSN 00221139

Das, Suman, Morvan, Frederic, Jourde, Benjamin, Minetti, Giulia, Brebbia, Pascale, Toussaint, Gauthier, Glass, David and Fornaro, Mara (2017) ATP Citrate Lyase regulates myofiber differentiation by altering histone acetylation. Cell reports, 21 (11). pp. 3003-3011. ISSN 22111247

Das, Suman, Morvan, Frederic, Morozzi, Giulio, Jourde, Benjamin, Minetti, Giulia, Kahle, Peter, Rivet, Helene, Brebbia, Pascale, Toussaint, Gauthier, Glass, David and Fornaro, Mara (2017) ATP Citrate Lyase Regulates Myofiber Differentiation and Increases Regeneration by Altering Histone Acetylation. Cell reports, 21 (11). pp. 3003-3011. ISSN 2211-1247

Daugvilaite, Viktorija, Madsen, Christian Medom, Lückmann, Michael, Echeverria, Clara Castello, Sailer, Andreas, Frimurer, Thomas Michael, Rosenkilde, Mette Marie and Benned-Jensen, Tau (2017) Biased signaling and allosteric modulation of G protein-coupled receptor 183 - a 7TM receptor also known as Epstein-Barr virus -induced gene 2. British journal of pharmacology. ISSN 1476-5381; 0007-1188

Davis, John, Kagan, Mark, Read, Jessica, Walles, Markus and Hatsis, Panagiotis (2017) Immunoprecipitation LC-MS Middle-up Approach for In Vivo Drug-To-Antibody Ratio Determination for Antibody Drug Conjugates. Bioanalysis.

Decker, Rebekah (2017) Articular cartilage and joint development from embryogenesis to adulthood. Seminars in cell & developmental biology, 62. pp. 50-56. ISSN 1096-3634

Decker, Rebekah, Um, Hyo-Bin, Dyment, Nathaniel A., Cottingham, Naiga, Usami, Yu, Enomoto-Iwamoto, Motomi, Kronenberg, Mark S., Maye, Peter, Rowe, David W., Koyama, Eiki and Pacifici, Maurizio (2017) Cell origin, volume and arrangement are drivers of articular cartilage formation, morphogenesis and response to injury in mouse limbs. Developmental biology, 426 (1). pp. 56-68. ISSN 00121606

Defontis, Myriam, Cote, Serge and Ledieu, David (2017) A combined approach to early detect in vitro drug-induced hemostatic changes in preclinical safety. Experimental and Toxicologic Pathology. ISSN 1618-1433

Del Signore, Susanna and Roubenoff, Ronenn (2017) Physical frailty and sarcopenia (PF&S): a point of view from the industry. Aging Clinical and Experimental Research, Epub a. pp. 1-6. ISSN 17208319

Dex, Sarah, Alberton, Paolo, Willkomm, Lena, Soellradl, Thomas, Bago, Sandra, Milz, Stefan, Shakibaei, Mehdi, Ignatius, Anita, Bloch, Wilhelm, Clausen-Schaumann, Hauke, Shukunami, China, Schieker, Matthias and Docheva, Denitsa (2017) Tenomodulin is Required for Tendon Endurance Running and Collagen I Fibril Adaptation to Mechanical Load. EBioMedicine, 20. pp. 240-254. ISSN 2352-3964

Dickson, Callum, Hornak, Viktor, Pearlstein, Robert and Duca, Jose (2017) Structure-kinetic relationships of passive membrane permeation from multiscale modeling. Journal of the American Chemical Society JACS., 139 (1). pp. 442-452.

Dickson, Callum, Pearlstein, Robert and Hornak, Viktor (2017) Contributions of the membrane dipole potential to the function of voltage-gated cation channels and modulation by small molecule potentiators. Biochimica et biophysica acta (BBA) - Biomembranes, 1859 (2). pp. 177-194. ISSN 00052736

Dumouchel, Jennifer, Argikar, Upendra, Spear, Jaimie, Brown, Ann, Dunne, Christine, Kramlinger, Valerie, Cirello, Amanda and Gunduz, Mithat (2017) An in vitro Investigation of Ocular Bioactivation Potential and the Role of CytochromeP450 2D Enzymes in Rat. Drug metabolism letters.. ISSN 1874-0758

Dégardin, Klara, Desponds, Anne and Roggo, Yves (2017) Protein-based medicines analysis by Raman spectroscopy for the detection of counterfeits. Forensic Science International, 278. pp. 313-325. ISSN 03790738

Dégardin, Klara and Roggo, Yves (2017) Innovative Strategy for Counterfeit Analysis. Medicine Access @ Point of Care, 1 (1). maapoc.0000013. ISSN 2399-2026

de Moura França, Leandro , Amigo, José Manuel , Cairós, Carlos , Bautista Mercader, Manuel and Fernanda Pimentel, Maria (2017) Evaluation and assessment of homogeneity in images. Part 1: Unique homogeneity percentage for binary images. Chemometrics and Intelligent Laboratory Systems, 171. pp. 26-39. ISSN 0169-7439

E

Ebata, Kevin T., Mesh, Kathryn, Liu, Shichong, Bilenky, Misha, Fekete, Alexander, Acker, Michael, Hirst, Martin, Garcia, Benjamin A and Ramalho-Santos, Miguel (2017) Vitamin C Induces Specific Demethylation of H3K9me2 in Mouse Embryonic Stem Cells via Kdm3a/b. Epigenetics & chromatin, 10. p. 36. ISSN 1756-8935

Ebhardt, H. Alexander, Degen, Simone, Tadini, Valentina, Schilb, Alain, Greig, Carolyn A., Fearon, Kenneth CH, Aebersold, Ruedi and Jacobi, Carsten (2017) Comprehensive proteome analysis of muscle composition and development in seniors. EMBO Molecular Medicine.

Eder, Joerg (2017) Opportunities and challenges in phenotypic drug discovery: An industry perspective. Nature Reviews Drug Discovery, 16 (8). pp. 531-543. ISSN 14741784

Edge, Stephen, Singh, Dilraj, Lewis, David and Rouse, Tim (2017) Defining the “Dose” for Dry Powder Inhalers: The challenge of correlating in-vitro dose delivery results with clinical efficacy. American pharmaceutical review, 20 (3). pp. 54-62.

Egger, Christine, Cannet, Catherine, Gerard Sachot, Christelle, Pierrat, Benoit, Suply, Thomas, Ksiazek, Iwona and Beckmann, Nicolau (2017) Effects of the fibroblast activation protein inhibitor, PT100, in a murine model of pulmonary fibrosis. European Journal of Pharmacology, 809. pp. 64-72. ISSN 18790712

Einolf, Heidi, Lin, Wen, Wang, Lai, Gu, Helen, Chun, Dung Y., Mangold, James B. and He, Handan (2017) Physiologically-based pharmacokinetic model predictions of panobinostat (LBH589) as a victim and perpetrator of drug-drug interactions. Drug Metabolism and Disposition.

Einolf, Heidi, Zhou, Jocelyn, Won, Christina, Wang, Lai and Rebello, Sam (2017) A physiologically-based pharmacokinetic modeling approach to predict drug-drug interactions of sonidegib (LDE225) with perpetrators of CYP3A in cancer patients. Drug metabolism and disposition, 45 (4). pp. 361-374. ISSN 1521-009X

Emery, Caroline, Monaco, Kelli-Ann, Wang, Ping, Balak, Marissa, Freeman, Alyson, Meltzer, Jodi, Delach, Scott, Rakiec, Daniel, Ruddy, David, Korn, Joshua, Haling, Jake, Acker, Michael and Caponigro, Giordano (2017) BRAF-inhibitor associated MEK mutations increase RAF-dependent and -independent enzymatic activity. Molecular Cancer Research, 15 (10). pp. 1431-1444. ISSN 1557-3125

Ertl, Peter (2017) An algorithm to identify functional groups in organic molecules. Journal of cheminformatics, 9 (1). p. 36. ISSN 1758-2946

Ertl, Peter, Lewis, Richard, Martin, Eric and Polyakov, Valery (2017) In silico generation of novel, drug-like chemical matter using the LSTM neural network. arXiv / talk at CCG User Group Meeting.

Estoppey, David, Hewett, Jeffrey, Guy, Chantale, Harrington, Edmund, Thomas, Jason, Schirle, Markus, Cuttat-Theurillat, Rachel, Waldt, Annick, Gerrits, Bertran, Yang, Zinger, Schuierer, Sven, Carbone, Walter, Knehr, Judith, Lindeman, Alicia, Russ, Carsten, Frias, Elizabeth, Hoffman, Gregory, Varadarajan, Malini, Ramadan, Nadire, Reece-Hoyes, John, Wang, Qiong, Chen, Xin, Mcallister, Gregory, Roma, Guglielmo, Bouwmeester, Antonius and Hoepfner, Dominic (2017) Identification of a novel NAMPT inhibitor by CRISPR/Cas9 chemogenomic profiling in mammalian cells. Scientific reports, 7 (42728). pp. 1-6. ISSN 2045-2322

Estoppey, David, Lee, Chia Min, Janoschke, Marco, Mathys, Philippe, Filipuzzi, Ireos, Schuhmann, Tim, Riedl, Ralph, Aust, Thomas, Galuba, Olaf, Mcallister, Gregory, Russ, Carsten, Spiess, Martin, Bouwmeester, Antonius, Bonamy, Ghislain and Hoepfner, Dominic (2017) The Natural Product Cavinafungin Selectively Interferes with Zika and Dengue Virus Replication by Inhibition of the Host Signal Peptidase. Cell Reports, 19 (3). pp. 451-460. ISSN 22111247

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Fairfield, Heather, Falank, Carolyne, Harris, Elizabeth, Demambro, Victoria, McDonald, Michelle, Pettitt, Jessica A., Mohanty, Sindhu T., Croucher, Peter, Kramer, Ina, Kneissel, Michaela, Rosen, Clifford J. and Reagan, Michaela R. (2017) The skeletal cell-derived molecule sclerostin drives bone marrow adipogenesis. Journal of cellular physiology.

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Filipuzzi, Ireos, Thomas, Jason, Pries, Verena, Estoppey, David, Salcius, Michael, Studer, Christian, Schirle, Markus and Hoepfner, Dominic (2017) Direct interaction of Chivosazole F with actin elicits cell responses similar to Latrunculin A but distinct from Chondramide. ACS chemical biology. ISSN 1554-8929

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Furegati, Markus and Nocito, Sandro (2017) Practial isolation of the (1R,2R)-enantiomer from a racemic cis/trans mixture of 2-methylcyclohexyl-1-amine. Organic process research & development.

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Gallou, Fabrice and Fu, Jiping (2017) Development of a Cyclosporin derivative and of its synthesis as cyclophilin inhibitor with excellent anti-HCV potency. Bioorganic and Medecinal Chemistry.

Gallou, Fabrice and Handa, Sachin (2017) Micelle-Enabled Sustainable Heteroleptic Palladium Catalysis for Nitroalkane Arylations in Water Under Mild Conditions. ACS Catalysis.

Gallou, Fabrice and Lipshutz, Bruce (2017) Effects of Co-solvents on Reactions Run Under Micellar Catalysis Conditions. Organic letters, 19. pp. 194-197.

Gallou, Fabrice and Lipshutz, Bruce (2017) Fe/ppm Cu nanoparticles as a recyclable catalyst for click reactions in water at room temperature. Green Chemistry, 19. pp. 2106-2109.

Gallou, Fabrice and Lipshutz, Bruce (2017) From Milligrams to Grams. SNAr Reactions in Aqueous Nanomicelles; No Dipolar Aprotic Solvents Needed. Org. Proc. Res. Dev., 2017 (21). pp. 218-221.

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Gan, Xin, Wang, Haifeng, Yu, Yanyan, Yi, Wei, Zhu, Shanshan, Gu, Baohua, Lu, Chris, Li, En and Liang, Yu (2017) Epigenetically repressing human Cytomegalovirus lytic infection and reactivation from latency in THP-1 model by targeting H3K9 and H3K27 histone demethylases. PLoS ONE, 12 (4). ISSN 1932-6203

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Gembarska, Agnieszka, Durand, Eric, Mandon, Emeline, Estadieu, Claire, Romanet, Vincent, Wiesmann, Marion, Lehar, Joseph, Tiedt, Ralph, De Weck, Antoine, Kauffmann, Audrey, Sutter, Esther, Grevot, Armelle, Moulin, Pierre, Murakami, Masato, Sellers, William, Hofmann, Francesco, Jensen, Michael Rugaard, Chapeau, Emilie and Rad, Roland (2017) Resistance mechanisms to TP53-MDM2 inhibition identified by in vivo piggyBac transposon mutagenesis screen in an Arf-/-mouse model. Proceedings of the National Academy of Sciences of the United States of America, 114 (12). pp. 3151-3156. ISSN 1091-6490

Gergely, Peter (2017) Challenges and opportunities of drug research and development in rare diseases. Journal of international pharmaceutical research.

Ghosh, Joy, Nguyen, Andrew, Bigelow, Chad, Poor, Stephen, Qiu, Yubin, Rangaswamy, Nalini, Ornberg, Richard, Jackson, Brittany, Mak, Howard, Ezell, Tucker, Ashminova, Vania, De La Cruz, Elisa, Carrion, Ana, Etemad-Gilbertson, Bijan, Garcia Caro, Roxana, Zhu, Kan, George, Vinney, Bai, Jirong, Sharma, Radhika, Shen, Siyuan, Wang, Yiqin, Subramanian, Kulandayan, Fassbender, Elizabeth, Maker, Michael, Hanks, Shawn, Vrouvlianis, Joanna, Leehy, Barrett, Long, Debby, Prentiss, Melissa, Kansara, Viralbhai, Jaffee, Bruce, Dryja, Ted and Roguska, Michael (2017) Long-acting protein drugs for the treatment of ocular diseases. Nature communications, 8. pp. 1-10. ISSN 2041-1723

Giggins, Oonagh, Clay, Ieuan and Walsh, Lorcan (2017) Physical Activity Monitoring in Patients with Neurological Disorders: A Review of the Validity and Reliability of Body Worn Monitors. Digital Biomarkers.

Ginster, Stefanie, Bardet, Maureen, Unterreiner, Adeline, Malinverni, Claire, Renner, Florian, Lam, Stephen, Freuler, Felix, Gerrits, Bertran, Voshol, Johannes, Calzascia, Thomas, Regnier, Catherine, Renatus, Martin, Nikolay, Rainer, Israel, Laura and Bornancin, Frederic (2017) Two antagonistic MALT1 auto-cleavage mechanisms reveal a role for TRAF6 to unleash MALT1 activation. PLoS ONE, 12 (1). e0169026. ISSN 1932-6203

Glorieux, Francis, Devogalaer, Jean-Pierre, Durigova, Michaela, Goemaere, Stefan, Hemsley, Sarah, Junker, Uwe, Ruckle, Jon, Seefried, Lothar and Winkle, Peter (2017) BPS804 Anti-Sclerostin Antibody in Adults With Moderate Osteogenesis Imperfecta: Results of a Randomized Phase 2a Trial. Journal of Bone and Mineral Research, 32 (7). pp. 1496-1504. ISSN 15234681

Glowienke, Susanne (2017) p-Aminophenol monograph. Regul Pharm Tox.

Godinez Navarro, William Jose, Hossain, Imtiaz, Lazic, Stanley, Davies, John and Zhang, Xian (2017) A Multi-scale Convolutional Neural Network for Phenotyping High Content Cellular Images. Bioinformatics. ISSN 1367-4811; 1367-4803

Goepfert, Arnaud, Lehmann, Sylvie, Wirth, Emmanuelle and Rondeau, Jean-Michel (2017) The human IL-17A/F heterodimer: a two-faced cytokine with unique receptor recognition properties. Scientific reports, 7. p. 8906. ISSN 2045-2322

Gotwals, Philip, Cameron, Scott, Cipolletta, Daniela, Cremasco, Viviana, Crystal, Adam, Hewes, Becker, Mueller, Britta, Petruzzelli, Lilli, Quaratino, Sonia, Sabatos-Peyton, Catherine and Dranoff, Glenn (2017) Prospects for combining targeted and conventional cancer therapy with immunotherapy. Nature Reviews Cancer, 17 (5). pp. 286-301. ISSN 1474-1768

Goyal, Lipika, Supriya, Saha K, Liu, Lea Y, Siravegna, Giulia, Leshchiner, Ignaty, Ahronian, Leanne G, Lennerz, Jochen K, Vu, Phuong, Deshpande, Vikram, Kambadakone, Avinash, Mussolin, Benedetta, Reyes, Stephanie, Henderson, Laura , Sun, Jiaoyuan Elisabeth, Van Seventer, Emily E, Gurski, Joseph M Jr, Baltschukat, Sabrina, Schacher Engstler, Barbara, Barys, Louise, Furet, Pascal, Ryan, David P, Stone, James R, Iafrate, John A, Getz, Gad, Graus Porta, Diana, Tiedt, Ralph, Bardelli, Alberto, Juric, Dejan, Corcoran, Ryan B, Bardeesy, Nabeel and Zhu, Andrew X (2017) Polyclonal secondary FGFR2 mutations drive acquired resistance to FGFR inhibition in FGFR2 fusion-positive cholangiocarcinoma patients. Cancer discovery. ISSN 2159-8290; 2159-8274

Groth, K, Berezhanskyy, T, Aneja, MK, Geiger, J, Schweizer, M, Maucksch, L, Pasewald, T, Brill, T, Tigani, Bruno, Weber, Eckhard, Rudolph, C and Hasenpusch, G (2017) Tendon healing induced by chemically modified mRNAs. European cells and materials, 33. pp. 294-307. ISSN 1473-2262

Grove, Kerri, Kansara, Viralbhai, Prentiss, Melissa, Long, Debby, Mogi, Muneto, Kim, Sean and Rudewicz, Patrick (2017) Application of Imaging Mass Spectrometry to Assess Ocular Drug Transit. Journal of biomolecular screening. ISSN 1552-454X; 1087-0571

Grunewald, Jan, Jin, Yunho, Vance, Julie, Read, Jessica, Wang, William, Wan, Yongqin, Zhou, Huanfang, Ou, Weijia, Klock, Heath, Peters, Eric, Uno, Tetsuo, Brock, Ansgar and Geierstanger, Bernhard (2017) Optimization of an Enzymatic Antibody Drug Conjugation Ap-proach based on CoA Analogs. Bioconjugate chemistry. ISSN 1520-4812; 1043-1802

Gu, Helen, Dutreix, Catherine, Rebello, Sam, Ouatas, Taoufik, Wang, Lai, Chun, Dung Yu, Einolf, Heidi and He, Handan (2017) Simultaneous physiologically-based pharmacokinetic (PBPK) modeling of parent and active metabolites to investigate complex CYP3A4 drug-drug interaction potential: a case example of midostaurin. Drug metabolism and disposition.

Gubler, Hanspeter, Clare, Nicholas, Galafassi, Laurent, Girod, Michel, Herr, Guy and Geissler, Uwe (2017) Helios - History and Anatomy of a successful in-House Enterprise High-Throughput Screening and Profiling Data Analysis System. SLAS Discovery, 23 (5). pp. 474-488. ISSN 2472-5552

Guendisch, Ulf, Weiss, Jessica, Ecoeur, Florence, Riker, Julia, Kaupmann, Klemens, Kallen, Joerg, Hintermann, Samuel, Orain, David, Dawson King, Janet, Billich, Andreas and Guntermann, Christine (2017) Pharmacological inhibition of ROR gamma t suppresses the Th17 pathway and alleviates antigen-induced arthritis in-vivo. PLoS ONE, 12 (PLoS O). pp. 1-25. ISSN 1932-6203

Guntermann, Christine, Piaia, Alessandro, Hamel, Marie-Laure, Theil, Diethilde, Rubic-Schneider, Tina, Del Rio Espinola, Alberto, Dong, Linda, Billich, Andreas, Kaupmann, Klemens, Dawson King, Janet, Hoegenauer, Klemens, Orain, David, Hintermann, Samuel, Stringer, Rowan, Patel, Dhavalkumar, Doelemeyer, Arno, Deurinck, Mark and Schuemann, Jens (2017) Retinoic-acid-orphan-receptor C inhibition suppresses Th17 cells and induces thymic aberrations. The Journal of Clinical Investigation Insight (JCI Insight).

Guo, Hongqiu, Yeboah, Fred, Camargo, L. Miguel, Digan, Mary Ellen, Niu, Honglin, Pan, Yue, Reiling, Stephan, Soler-Llavina, Gil, Wang, Hao-Ran, Shanker, Gopi, Stams, Travis, Bill, Anke and Weihofen, Wilhelm (2017) A NMDA-receptor calcium influx assay sensitive to stimulation by glutamate and glycine/D-serine. Nature methods, 7 (1). p. 11608.

Gusev, Arkady and Wang, Tianke (2017) Ensuring quality and compliance in outsourcing of bioanalysis of clinical biomarkers. Bioanalysis, 9 (7). pp. 501-504. ISSN 1757-6199

Gutierrez, Marcelo, Spector, Jonathan, Felix, Sandra Daniela, Romero, Fernando, Pillai, Goonaseelan, Onyango, Kevin, Owusu-Agyei, Seth, Asante, Kwaku-Poku, Barnes, Karen, Allen, Elizabeth, Sinxadi, Phumla, Abdulla, Salim, Masimirembwa, Collen, Munyoro, Michelle, Yimer, Getnet, Gebre-Mariam, Tsige and Ogutu, Bernhards (2017) *Building capability for clinical pharmacology research in sub-Saharan Africa*. Clinical pharmacology and therapeutics. ISSN 1532-6535; 0009-9236

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Hafner, Andreas, Mancino, Valentina, Meisenbach, Mark, Schenkel, Berthold and Sedelmeier, Joerg Mathias (2017) Dichloromethyl lithium: A valuable reagent in organic synthesis handled in continuous flow mode. Dichloromethyl lithium: A valuable reagent in organic synthesis handled in continuous flow mode.

Hamze, Moustafa, Meunier, Sylvain, Karle, Anette, Gdoura, Abdelaziz, Goudet, Amelie, Szely, Natacha, Pallardy, Marc, Carbonnel, Franck, Spindeldreher, Sebastian, Mariette, Xavier, Miceli-Richard, Corinne and Maillere, Bernard (2017) Characterization of CD4 T cell epitopes of infliximab and rituximab identified from healthy donors. Frontiers in immunology, 8 (MAY). pp. 1-11. ISSN 1664-3224

Han, Yi, Ayalasomayajula, Surya, Yang, Fan, Yuan, Yaozong, Langenickel, Thomas Heiko, Hinder, Markus, Kalluri, Sampath, Pal, Parasar and Sunkara, Gangadhar (2017) Pharmacokinetics, Safety and Tolerability of Sacubitril/Valsartan (LCZ696) After Single-Dose Administration in Healthy Chinese Subjects. European Journal of Drug Metabolism and Pharmacokinetics, 42 (1). pp. 109-116. ISSN 2107-0180

Hart, Lori, Rader, JulieAnn, Raman, Pichai, Batra, Vandana, Tsang, Matthew, Gagliardi, Maria, Martinez, Daniel, Wood, Andrew, Kim, Sunkyu, Parasuraman, Sudha, Delach, Scott, Cole, Kristina, Shiva, Krupa, Caponigro, Giordano, Peters, Malte, Boehm, Markus and Maris, John (2017) Preclinical therapeutic synergy of MEK1/2 and CDK4/6 inhibition in neuroblastoma. Clinical Cancer Research, 23 (7). pp. 1785-1796. ISSN 1557-3265

Hatsis, Panagiotis, Waters, Nigel and Argikar, Upendra (2017) Implications for Metabolite Quantification by Mass Spectrometry in the Absence of Authentic Standards. Drug Metabolism and Disposition.

Hayes, Lilian, M., Press, Neil, Tocher, Derek, A. and Carmalt, Claire, J. (2017) Intermolecular interactions between encapsulated aromatic compounds and the host framework of a Crystalline Sponge. Crystal Growth & Design, 17 (2). pp. 858-863. ISSN 1528-74831528-7505

He, Handan, Tran, Phi, Gu, Helen, Tedesco, Vivienne, Zhang, Jin, Lin, Wen, Gatlik, Ewa, Klein, Kai and Heimbach, Tycho (2017) Midostaurin, a Novel Protein Kinase Inhibitor for the Treatment of Acute Myelogenous Leukemia: Insights from Human Absorption, Metabolism, and Excretion Studies of a BDDCS II Drug. Drug metabolism and disposition: the biological fate of chemicals, 45 (5). pp. 540-555. ISSN 1521-009X

He, Xiaohui, DaRos, Sara, Zhu, Xuefeng, Nelson, John, Michellys, Pierre, Iskandar, Maya, Espinola, Sheryll, Bursulaya, Badry, Gao, Mu-Yun, Kreusch, Andreas, Baaten, Janine, Clemmer, Leah, Meeusen, Shelly, Huang, David, Hill, Robert, Nguyen-Tran, Van, Fathman, John, Liu, Bo, Tuntland, Tove, Ng, Kenneth, Shi, Jian, Bordone, Laura and Liu, Hong (2017) Identification of Potent and Selective RIPK2 Inhibitors for the Treatment of Inflammatory Diseases. ACS Medicinal Chemistry Letters. ISSN 1948-58751948-5875

Helliwell, Stephen, Filipuzzi, Ireos, Steffen, Janos and Koehler, Carla (2017) Stendomycin selectively inhibits TIM23-dependent mitochondrial protein import. Nature Chemical Biology. ISSN 1552-44501552-4469

Hoegenauer, Klemens, Soldermann, Nicolas, Zecri, Frederic, Strang, Ross, Graveleau, Nadege, Wolf, Romain, Cooke, Nigel Graham, Smith, Alexander Baxter, Hollingworth, Greg, Blanz, Joachim, Gutmann, Sascha, Rummel, Gabriele, Littlewood-Evans, Amanda and Burkhart, Christoph (2017) Discovery of CDZ173 (Leniolisib), Representing a Structurally Novel Class of PI3K Delta-Selective Inhibitors. ACS Medicinal Chemistry Letters, 8 (9). pp. 975-980. ISSN 19485875

Hoffmann, Peter (2017) An Evaluation of the Drug-induced Changes in Cardiac Inotropy (LVdP/dt40 and QA Interval) and Lusitropy (LVdP/dtmin and Tau) in Dogs: Results from a HESI-sponsored consortium. An Evaluation of the Drug-induced Changes in Cardiac Inotropy (LVdP/dt40 and QA Interval) and Lusitropy (LVdP/dtmin and Tau) in Dogs: Results from a HESI-sponsored consortium, Journa (85). pp. 1-21.

Holzer, Philipp (2017) Discovery of potent and selective p53-MDM2 protein-protein interaction inhibitors as anticancer drugs. Chimia : international journal for chemistry, 71 (10). pp. 716-721. ISSN 0009-4293

Horman, Shane, To, Jeremy, Lamb, John, Zoll, Jocelyn, Leonetti, Nicole, Tu, Buu, Moran, Rita, Newlin, Robbin, Walker, John and Orth, Anthony (2017) Functional profiling of microtumors to identify cancer associated fibroblast-derived drug targets. Oncotarget, 8 (59). pp. 99913-99930. ISSN 19492553

Hu, Tiancen, Sprague, Elizabeth, Fodor, Michelle, Stams, Travis, Clark, Kirk and Jacob, Sandra (2017) The impact of structural biology in medicine illustrated with four case studies. Journal of Molecular Medicine. pp. 1-11. ISSN 14321440

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Ian, Harrow, Ernesto, Jimenez-Ruiz, Splendiani, Andrea, Martin, Romacker, Peter, Wollard, Scott, Markel, Yasmin, Alam-Faruque, Martin, Koch, James, Malone and Arild, Waaler (2017) Matching Disease and Phenotype Ontologies in the Ontology Alignment Evaluation Initiative. Journal of biomedical semantics, 8 (1). p. 55. ISSN 2041-1480

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Jain, Jay Prakash, Leong, Franz Joel Wen, Chen, Lanna, Kalluri, Sampath, Koradia, Vishal, Stein, Daniel, Wolf, Marie-Christine, Sunkara, Gangadhar and Kota, Jagannath (2017) Bioavailability of lumefantrine is significantly enhanced with a novel formulation approach, an outcome from a randomized, Open-label pharmacokinetic study in healthy volunteers. Antimicrobial Agents and Chemotherapy, 61 (9). ISSN 1098-6596

James, Alexander David, Marvalin, Cyrille, Luneau, Alexandre, Meissner, Axel and Camenisch, Gian P. (2017) Comparison of 19F-NMR and 14C measurements for the assessment of ADME of BYL719 (Alpelisib) in humans. Drug metabolism and disposition, 45. pp. 900-907. ISSN 1521-009X

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Jelsch, Morgane and Grandeury, Arnaud (2017) Crystal Morphology Prediction of active pharmaceutical ingredients. Internship - report for school.

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Ji, Lei, Jiang, Xiaomo, Kheifets, Olga, Chen, Amy, Mickanin, Craig, Bauer, Andreas, Cong, Feng, Jiang, Bo, Xu, wenqing and Yan, Xiaoxue (2017) The SIAH E3 ubiquitin ligases promote Wnt/β-catenin signaling through mediating Wnt-induced Axin degradation. Genes and Development, 31 (9). pp. 904-915. ISSN 1549-5477

Jia, Haoruo, Ma, Xiaoyuan, Tong, Wei, Wei, Yulong , Tower, Robert, Chandra, Abhishek, Wang, Luqiang, Sun, Zeyang, Yang, Zhaochun, Badar, Farid, Zhang, Kairui, Tseng, Wei-ju, Kramer, Ina, Kneissel, Michaela, Xia, Yang, Liu, X. Sherry, Wang, James H-C., Han, Lin, Enomoto-Iwamoto, Motomi and Qin, Ling (2017) Subchondral bone plate sclerosis during late osteoarthritis is caused by loading-induced reduction in Sclerostin. Arthritis and rheumatology.

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Plawinski, Jason, Reinker, Stefan, Kirkpatrick, Nathaniel and Oakeley, Edward James (2017) Summer internship at Novartis. Report to University of Strasbourg, France.

Pognan, Francois and Marc, Philippe (2017) Legacy data sharing to improve drug safety assessment: The eTOX project. Nature Reviews Drug Discovery, 16 (12). pp. 811-812. ISSN 14741784

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Robbins, Ken (2017) Sparse set of AWS tips for an enterprise cloud transformation. Ken Robbins' LinkedIn blog.

Roggo, Yves (2017) Forensic investigation in the pharmaceutical industry: Identification procedure of visible particles in (drug) solutions and different containers by combining vibrational and X-ray spectroscopic techniques. Journal of pharmaceutical and biomedical analysis. ISSN 1873-264X; 0731-7085

Roggo, Yves (2017) Global regression model for moisture content determination using near-infrared spectroscopy. European journal of pharmaceutics and biopharmaceutics. ISSN 1873-3441; 0939-6411

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Schlesinger, Ann and Hunt, Ian (2017) Video of 2016 Novartis Open Framework Symposium. this link was shared with externals but not published.

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Silver-Brown, Serena, Hoffman, Ann, Horvath, Peter, Lovitt, Carrie, Easton, Evan, LaBarbera, Daniel, Mendez, Melissa, Rothernberg, Mark, Seldin, Jan and Fennell, Myles (2017) SBI2 HCS/HCA 3D Imaging: Best Practices and Unmet Needs Colloquium. Assay and drug development technologies, 15 (1). pp. 1-7.

Sivasankaran, Rajeev, Teider, Natalia, Mcnally, Anna, Bradner, Jay and Worringer, Katie (2017) Synthetic Transcription Elongation Factors license transcription across repressive heterochromatin. Science. pp. 1617-1622.

Skilitsi, Anastasia Ioanna, Turko, Timothé, Cianfarani, Damien, Barre, Sophie, Uhring, Wilfried, Hassiepen, Ulrich and Léonard, Jérémie (2017) Towards Sensitive, High-Throughput, Biomolecular Assays Based on Fluorescence Lifetime. Methods and applications in fluorescence /. ISSN 2050-6120

Skolnik, Suzanne, Geraci, Gina and Dodd, Stephanie (2017) AUTOMATED SUPERATURATION STABILITY ASSAY TO DIFFERENTIATE POORLY SOLUBLE COMPOUNDS IN DRUG DISCOVERY. Journal of pharmaceutical sciences. ISSN 1520-6017

Skolnik, Suzanne, Geraci, Gina and Dodd, Stephanie (2017) Automated Supersaturation Stability Assay to Differentiate Poorly Soluble Compounds in Drug Discovery. Journal of Pharmaceutical Sciences. ISSN 1520-6017

Skora, Lukasz and Jahnke, Wolfgang (2017) 19F-NMR-based dual-site reporter assay for the discovery and distinction of catalytic and allosteric kinase inhibitors. ACS medicinal chemistry letters, 8. pp. 632-635.

Skora, Lukasz, Jahnke, Wolfgang, Sijbesma, Eline, Leysen, Seppe, Brunsveld, Luc, Wolf, Alexander, Nussbaumer, Peter and Ottmann, Christian (2017) Identification of Two Secondary Ligand Binding Sites in 14-3-3 Proteins Using Fragment Screening. Biochemistry, 56 (30). pp. 3972-3982. ISSN 15204995

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Sullivan, Ryan (2017) CD56bright NK cells exhibit potent antitumor responses following IL-15 priming. Journal of Clinical Investigation, 127 (11). pp. 4042-4058. ISSN 0021-9738

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Swaller, Tim (2017) GNF recipient of the 2017 IEA Earth Month Award. GNF Website Recent Updates section.

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