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Synthetic Approaches to the New Drugs Approved during 2015

Liu, Kevin, Flick, Andrew C, Ding, Hong X, Leverett, Carolyn A, Kyne, Robert E K, Fink, Sarah J and O'Donnell, Christopher J (2017) Synthetic Approaches to the New Drugs Approved during 2015. Journal of Medicinal Chemistry, 60 (15). pp. 6480-6515. ISSN 1520-4804


New drugs introduced to the market every year represent privileged structures for particular biological targets. These new chemical entities (NCEs) provide insight into molecular recognition while serving as leads for designing future new drugs. This annual review describes the most likely process-scale synthetic approaches to 29 new chemical entities (NCEs) that were approved for the first time in 2015.

Item Type: Article
Date Deposited: 25 Nov 2017 00:45
Last Modified: 25 Jan 2019 00:45


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