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Items where Year is 2009

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Number of items: 279.


Adachi, Y., Li, R., Yamamoto, H., Min, Y., Piao, W., Wang, Y., Imsumran, A., Li, H., Arimura, Y., Lee, C.-T., Imai, K., Carbone, D. P. and Shinomura, Y. (2009) Insulin-like growth factor-I receptor blockade reduces the invasiveness of gastrointestinal cancers via blocking production of matrilysin. Carcinogenesis, 30 (8). pp. 1305-1313. ISSN 0143-3334

Albert, Mareike and Peters, Antoine (2009) Genetic and epigenetic control of early mouse development. Current Opinion in Genetics & Development, 19 (2). pp. 113-121. ISSN 1879-0380

Asparuhova, MB, Gelman, L and Chiquet, M (2009) Role of the actin cytoskeleton in tuning cellular responses to external mechanical stress. Scandinavian Journal of Medicine & Science in Sports. ISSN 1600-0838

Azziz, R, Carmina, E, Dewailly, D, Diamanti-Kandarakis, E, Escobar-Morreale, H F, Futterweit, W, Janssen, O E, Legro, R S, Norman, R J, Taylor, Ann and Witchel, S F (2009) The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report. Fertility and Sterility, 91 (2). pp. 456-488.


Bacher, Markus, Baumann, Karl, Knapp, Hermann, Steck, Andrea and Teibl, Sigrid (2009) Complete assignment of 1H and 13C NMR data of pravastatin derivatives. Magnetic Resonance in Chemistry : MRC, 47 (1). pp. 71-83. ISSN 1097-458X

Banerjee, Abhishek, Meredith, Rhiannon M., Rodriguez-Moreno, Antonio, Mierau, Susanna B., Auberson, Yves and Paulsen, Ole (2009) Double Dissociation of Spike Timing-Dependent Potentiation and Depression by Subunit-Preferring NMDA Receptor Antagonists in Mouse Barrel Cortex. Cerebral Cortex, 19 (12). pp. 2959-2969. ISSN 1047-3211

Baumann, Philipp, Hagemeier, Hilke, Mandl-Weber, Sonja, Franke, Daniel and Schmidmaier, Ralf (2009) Myeloma cell growth inhibition is augmented by synchronous inhibition of the insulin-like growth factor-1 receptor by NVP-AEW541 and inhibition of mammalian target of rapamycin by Rad001. Anti-Cancer Drugs, 20 (4). pp. 259-266. ISSN 0959-4973

Bell, Oliver and Schuebeler, Dirk (2009) Chromatin: sub out the replacement. Current Biology : CB, 19 (14). R545-R547. ISSN 1879-0445

Berrigan, David, Potischman, Nancy, Dodd, Kevin W, Hursting, Stephen D, Lavigne, Jackie, Barrett, James and Ballard-Barbash, Rachel (2009) Race/ethnic variation in serum levels of IGF-I and IGFBP-3 in US adults. Growth Hormone & IGF Research: official journal of the Growth Hormone Research Society and the International IGF Research Society, 19 (2). pp. 146-155. ISSN 1532-2238

Biedermann, Bjoern, Wright, Jane, Senften, Mathias, Kalchhauser, Irene, Sarathy, Gautham, Lee, Min-Ho and Ciosk, Rafal (2009) Translational Repression of Cyclin E Prevents Precocious Mitosis and Embryonic Gene Activation During C. elegans Meiosis. Developmental Cell, 17 (3). pp. 355-364. ISSN 1534-5807

Billich, Andreas, Urtz, Nicole, Reuschel, Roland and Baumruker, Thomas (2009) Sphingosine kinase 1 is essential for proteinase-activated receptor-1 signalling in epithelial and endothelial cells. The International Journal of Biochemistry & Cell Biology, 41 (7). pp. 1547-1555. ISSN 1878-5875

Blake, Katy L, O'Neill, Alex J, Mengin-Lecreulx, Dominique, Henderson, Peter J F, Bostock, Julieanne M, Dunsmore, Colin J, Simmons, Katie J, Fishwick, Colin W G, Leeds, Jennifer A and Chopra, Ian (2009) The nature of Staphylococcus aureus MurA and MurZ and approaches for detection of peptidoglycan biosynthesis inhibitors. Molecular microbiology, 72 (2). pp. 335-343. ISSN 1365-2958

Blevins, Todd, Pontes, Olga, Pikaard, Craig S and Meins, Frederick Jr. (2009) Heterochromatic siRNAs and DDM1 independently silence aberrant 5S rDNA transcripts in Arabidopsis. PloS One, 4 (6). e5932. ISSN 1932-6203

Boldogkoi, Zsolt, Balint, Kamill, Awatramani, Gautam B, Balya, David, Busskamp, Volker, Viney, Tim James, Lagali, Pamela, Duebel, Jens, Pasti, Emese, Tombacz, Dóra, Tóth, Judit S, Takacs, Irma F, Gross Scherf, Brigitte and Roska, Botond (2009) Genetically timed, activity-sensor and rainbow transsynaptic viral tools. Nature Methods, 6 (2). pp. 127-130. ISSN 1548-7105

Bonnet, Nicolas, Standley, Kara N., Bianchi, Estelle N., Stadelmann, Vincent, Foti, Michelangelo, Conway, Simon J, Ferrari, Serge L. and Kneissel, Michaela (2009) The Matricellular Protein Periostin Is Required for Sost Inhibition and the Anabolic Response to Mechanical Loading and Physical Activity. Journal of Biological Chemistry, 284 (51). pp. 35939-35950. ISSN 0021-9258

Boschmann, Michael, Engeli, Stefan, Dobberstein, Kerstin, Budziarek, Petra, Strauss, Anke, Boehnke, Jana, Sweep, Fred C G J, Luft, Friedrich C, He, Yan-Ling, Foley, James and Jordan, Jens (2009) Dipeptidyl-peptidase-IV inhibition augments postprandial lipid mobilization and oxidation in type 2 diabetic patients. Journal of Clinical Endocrinology & Metabolism, 94 (3). pp. 846-852. ISSN 0021-972X

Boucard, Christine, hernowa, aditya and frans, cornelissen (2009) Changes in cortical grey matter density associated with long-standing retinal visual field defects. Brain, 132 (7). pp. 1898-1906. ISSN 0006-8950

Bozulic, Lana and Hemmings, Brian Arthur (2009) PIKKing on PKB: regulation of PKB activity by phosphorylation. Current Opinion in Cell Biology, 21 (2). pp. 256-261. ISSN 1879-0410

Braun, Pascal, Tasan, Murat, Dreze, Matija, Barrios-Rodiles, Miriam, Lemmens, Irma, Yu, Haiyuan, Sahalie, Julie M, Murray, Ryan R, Roncari, Luba, de Smet, Anne-Sophie, Venkatesan, Kavitha, Rual, Jean-François, Vandenhaute, Jean, Cusick, Michael E, Pawson, Tony, Hill, David, Tavernier, Jan, Wrana, Jeffrey L, Roth, Frederick P and Vidal, Marc (2009) An experimentally derived confidence score for binary protein-protein interactions. Nature Methods, 6 (1). pp. 91-97. ISSN 1548-7105

Brellier, F, Tucker, Bob and Chiquet, Ruth (2009) Tenascins and their implications in diseases and tissue mechanics. Scandinavian Journal of Medicine & Science in Sports. ISSN 1600-0838

Breuleux, Madlaina, Klopfenstein, Matthieu, Stephan, Christine, Doughty, Cheryl A, Barys, Louise, Maira, Sauveur-Michel, Kwiatkowski, David and Lane, Heidi (2009) Increased AKT S473 phosphorylation after mTORC1 inhibition is rictor dependent and does not predict tumor cell response to PI3K/mTOR inhibition. Molecular Cancer Therapeutics, 8 (4). pp. 742-753. ISSN 1535-7163

Brigell, Mitchell (2009) The ERG in drug development: translation from animal models to human. Documenta Ophthalmologica. Advances in Ophthalmology, 118 (1). p. 1. ISSN 1573-2622

Bromley, C M, Close, S, Cohen, N, Favis, R, Fijal, B, Gheyas, F, Liu, W, Lopez-Correa, C, Prokop, A, Singer, Jonathan, Snapir, A, Tchelet, A, Wang, D and Goldstaub, D (2009) Designing pharmacogenetic projects in industry: practical design perspectives from the Industry Pharmacogenomics Working Group. Pharmacogenomics Journal, 9 (1). pp. 14-22. ISSN 1473-1150

Buehler, Marc (2009) RNA turnover and chromatin-dependent gene silencing. Chromosoma, 118 (2). pp. 141-151. ISSN 1432-0886

Buehler, Marc and Gasser, Susan (2009) Silent chromatin at the middle and ends: lessons from yeasts. The EMBO Journal, 28 (15). pp. 2149-2161. ISSN 1460-2075

Bystricky, Kerstin, Van Attikum, Haico, Montiel, Maria-Dolores, Dion, Vincent, Gehlen, Lutz and Gasser, Susan (2009) Regulation of nuclear positioning and dynamics of the silent mating type loci by the yeast Ku70/Ku80 complex. Molecular and Cellular Biology, 29 (3). pp. 835-848. ISSN 1098-5549


Cao, P, Maira, Sauveur-Michel, Garcia-Echeverria, Carlos and Hedley, D W (2009) Activity of a novel, dual PI3-kinase/mTor inhibitor NVP-BEZ235 against primary human pancreatic cancers grown as orthotopic xenografts. British Journal of Cancer, 100 (8). pp. 1267-1276. ISSN 1532-1827

Chatterjee, Saibal and Grosshans, Helge (2009) Active turnover modulates mature microRNA activity in Caenorhabditis elegans. Nature, 461 (7263). pp. 546-549. ISSN 0028-0836

Chedotal, Alain and Rijli, Filippo M (2009) Transcriptional regulation of tangential neuronal migration in the developing forebrain. Current Opinion in Neurobiology. ISSN 1873-6882

Chekulaeva, Marina and Filipowicz, Witold (2009) Mechanisms of miRNA-mediated post-transcriptional regulation in animal cells. Current Opinion in Cell Biology, 21 (3). pp. 452-460. ISSN 0955-0674

Chekulaeva, Marina, Filipowicz, Witold and Parker, Roy (2009) Multiple independent domains of dGW182 function in miRNA-mediated repression in Drosophila. RNA (New York, N.Y.), 15 (5). pp. 794-803. ISSN 1469-9001

Chen, Wei-qiang, Graf, Christine, Zimmel, David, Rovina, Philipp, Krapfenbauer, Kurt, Jaritz, Markus, Parker, Peter, Lubec, Gert and Bornancin, Frederic (2009) Ceramide Kinase Profiling by Mass Spectrometry reveals a Conserved Phosphorylation Pattern downstream of the Catalytic Site. Journal of Proteome Research, 9 (1). pp. 420-429. ISSN 1535-3893

Chene, Patrick, Rudloff, Joëlle, Schoepfer, Joseph, Furet, Pascal, Meier, Peter, Qian, Zhiyan, Schlaeppi, Jean-Marc, Schmitz, Rita and Radimerski, Thomas (2009) Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogue. BMC Chemical Biology, 9. p. 1. ISSN 1472-6769

Cherry, Timothy J, Trimarchi, Jeffrey M, Stadler, Michael B and Cepko, Constance L (2009) Development and diversification of retinal amacrine interneurons at single cell resolution. Proceedings of the National Academy of Sciences of the United States of America, 106 (23). pp. 9495-9500. ISSN 1091-6490

Chiquet, Matthias, Gelman, Laurent, Lutz, Roman and Maier, Silke (2009) From mechanotransduction to extracellular matrix gene expression in fibroblasts. Biochimica et Biophysica Acta, 1793 (5). pp. 911-920. ISSN 0006-3002

Cole, Andrew G, Metzger, Axel, Brescia, Marc-Raleigh, Qin, Lan-Ying, Appell, Kenneth C, Brain, Christopher, Hallett, Allan, Ganju, Pam, Denholm, Alastair, Wareing, James, Ritchie, Tim, Drake, Gillian, Bevan, Stuart, MacGloinn, Aisling, Mcbryde, Andrew, Patel, Viral, Oakley, Paul, Nunez, Ximena, Gstach, Hubert, Schneider, Peter, Baldwin, John J, Dolle, Roland E, McDonald, Edward and Henderson, Ian (2009) Sulfonamido-aryl ethers as bradykinin B1 receptor antagonists. Bioorganic & Medicinal Chemistry Letters, 19 (1). pp. 119-122. ISSN 1464-3405

Collingwood, Steve, Lock, Ruth and Searcey, Mark (2009) Optimising locally delivered drugs. Drug News and Perspectives, 22 (10). pp. 627-634. ISSN 0214-0934

Cotton, Jennifer, Tao, Jianshi and Balibar, Carl (2009) Identification and characterization of the Staphylococcus aureus gene cluster coding for staphyloferrin A. Biochemistry, 48 (5). pp. 1025-1035. ISSN 1520-4995

Cusick, Michael E, Yu, Haiyuan, Smolyar, Alex, Venkatesan, Kavitha, Carvunis, Anne-Ruxandra, Simonis, Nicolas, Rual, Jean-François, Borick, Heather, Braun, Pascal, Dreze, Matija, Vandenhaute, Jean, Galli, Mary, Yazaki, Junshi, Hill, David E, Ecker, Joseph R, Roth, Frederick P and Vidal, Marc (2009) Literature-curated protein interaction datasets. Nature Methods, 6 (1). pp. 39-46. ISSN 1548-7105


Daher, Aicha, Laraki, Ghislaine, Singh, Madhurima, Melendez-Pena, Carlos E, Bannwarth, Sylvie, Peters, Antoine, Meurs, Eliane F, Braun, Robert E, Patel, Rekha C and Gatignol, Anne (2009) TRBP control of PACT-induced phosphorylation of protein kinase R is reversed by stress. Molecular and Cellular Biology, 29 (1). pp. 254-265. ISSN 1098-5549

Damann, N, Owsianik, G, Li, S, Poll, Chris and Nilius, B (2009) The calcium-conducting ion channel transient receptor potential canonical 6 is involved in macrophage inflammatory protein-2-induced migration of mouse neutrophils. Acta physiologica (Oxford, England), 195 (1). pp. 3-11. ISSN 1748-1716

Daujat, Sylvain, Weiss, Thomas, Mohn, Fabio, Lange, Ulrike C, Ziegler-Birling, Celine, Zeissler, Ulrike, Lappe, Michael, Schuebeler, Dirk, Torres-Padilla, Maria-Elena and Schneider, Robert (2009) H3K64 trimethylation marks heterochromatin and is dynamically remodeled during developmental reprogramming. Nature Structural & Molecular Biology, 16 (7). pp. 777-781. ISSN 1545-9985

Day, Philip J, Cleasby, Anne, Tickle, Ian J, O'Reilly, Marc, Coyle, Joe E, Holding, Finn P, McMenamin, Rachel L, Yon, Jeff, Chopra, Rajiv, Lengauer, Christoph and Jhoti, Harren (2009) Crystal structure of human CDK4 in complex with a D-type cyclin. Proceedings of the National Academy of Sciences of the United States of America, 106 (11). pp. 4166-4170. ISSN 1091-6490

Degen, M, Goulet, S, Ferralli, Jacqueline, Roth, M, Tamm, M and Chiquet, Ruth (2009) Opposite effect of fluticasone and salmeterol on fibronectin and tenascin-C expression in primary human lung fibroblasts. Clinical and Experimental Allergy : journal of the British Society for Allergy and Clinical Immunology, 39 (5). pp. 688-699. ISSN 1365-2222

Dhaka, Ajay, Uzzell, Valerie, Dubin, Adrienne E, Mathur, Jayanti, Petrus, Matthew, Bandell, Michael and Patapoutian, Ardem (2009) TRPV1 is activated by both acidic and basic pH. The Journal of Neuroscience, 29 (1). pp. 153-158. ISSN 1529-2401

Dharia, Neekesh V, Sidhu, Amar BS, Cassera, María B, Westenberger, Scott J, Bopp, Selina ER, Eastman, Rich T, Plouffe, David, Batalov, Sergei, Park, Daniel J, Volkman, Sarah K, Wirth, Dyann F, Zhou, Yingyao, Fidock, David A and Winzeler, Elizabeth (2009) Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum. Genome Biology, 10 (2). R21-R21. ISSN 1465-6914

Dib, Amel, Glebov, Oleg K, Shou, Yaping, Singer, Robert H and Kuehl, W Michael (2009) A der(8)t(8;11) chromosome in the Karpas-620 myeloma cell line expresses only cyclin D1: yet both cyclin D1 and MYC are repositioned in close proximity to the 3'IGH enhancer. DNA Repair, 8 (3). pp. 330-335. ISSN 1568-7864

Dietemann, Patrick, Higgitt, Catherine, Kalin, Moritz, Edelmann, Michael J, Knochenmuss, Richard and Zenobi, Renato (2009) Aging and yellowing of triterpenoid resin varnishes - Influence of aging conditions and resin composition. Journal of Cultural Heritage, 10 (1). pp. 30-40. ISSN 1296-2074

Dietschy, Tobias, Shevelev, Igor, Pena-Diaz, Javier, Huehn, Daniela, Kuenzle, Sandra, Mak, Raymond, Miah, Mohammad Fahad, Hess, Daniel, Fey, Monika, Hottiger, Michael O, Janscak, Pavel and Stagljar, Igor (2009) p300-mediated acetylation of the Rothmund-Thomson-syndrome gene product RECQL4 regulates its subcellular localization. Journal of Cell Science, 122 (Pt 8). pp. 1258-1267. ISSN 0021-9533

Ding, Xavier C and Grosshans, Helge (2009) Repression of C. elegans microRNA targets at the initiation level of translation requires GW182 proteins. The EMBO Journal, 28 (3). pp. 213-222. ISSN 1460-2075

Ding, Xavier C, Weiler, Jan and Grosshans, Helge (2009) Regulating the regulators: mechanisms controlling the maturation of microRNAs. Trends in Biotechnology, 27 (1). pp. 27-36. ISSN 0167-7799

Dion, V and Wilson, JH (2009) Instability and chromatin structure of expanded trinucleotide repeats. Trends in Genetics : TIG. ISSN 0168-9525

Djimdé, Abdoulaye and Lefevre, Gilbert (2009) Understanding the pharmacokinetics of Coartem. Malaria journal, 8 (Suppl.1). S4. ISSN 1475-2875

Doering, Klaus, Meder, Gabriele, Hinnenberger, Manuela, Woelcke, Julian, Mayr, Lorenz and Hassiepen, Ulrich (2009) A fluorescence lifetime-based assay for protease inhibitor profiling on human kallikrein 7. Journal of Biomolecular Screening: the official journal of the Society for Biomolecular Screening, 14 (1). pp. 1-9. ISSN 1087-0571

Doucet, Julie, Canadi, Jasna, Kalis, Christoph, Valentin, Marie-Anne, Marrony, Severine, Deckert-Salva, Fabienne, Legay, Francois and Avrameas, Alexandre (2009) Reduction of matrix interferences by the combination of chaotropic salt and DMSO in a broadly applicable target-based ELISA for pharmacokinetic studies of therapeutic monoclonal antibodies. Journal of Pharmaceutical and Biomedical Analysis, 50 (5). pp. 924-931. ISSN 0731-7085

Dubrovska, Anna, Kim, Sungeun, Salamone, Richard, Walker, John, Maira, Sauveur-Michel, Garcia-Echeverria, Carlos, Schultz, Peter and Reddy, Venkateshwar (2009) The role of PTEN/Akt/PI3K signaling in the maintenance and viability of prostate cancer stem-like cell populations. Proceedings of the National Academy of Sciences of the United States of America, 106 (1). pp. 268-273. ISSN 1091-6490


Ehrlich, I and Luethi, Andreas (2009) New aids for learning and memory (Book Review). Nature Neuroscience, 12 (1). p. 3. ISSN 1097-6256

Ehrlich, Ingrid, Humeau, Yann, Grenier, François, Ciocchi, Stephane, Herry, Cyril and Luethi, Andreas (2009) Amygdala inhibitory circuits and the control of fear memory. Neuron, 62 (6). pp. 757-771. ISSN 1097-4199

Emmenbacher, M, Ronneberger, O, Ponti, Aaron, Schwarb, P, Griffa, A, Filippi, A, Nitschke, R, Driever, W and Burkhardt, H (2009) XuvTools: free, fast and reliable stitching of large 3D datasets. Journal of Microscopy, 233 (1). pp. 42-60. ISSN 0022-2720

Engels, Ingo, Daguia, Catherine, Huynh, Truc, Urbina, Hugo, Buddenkotte, Joerg, Schumacher, Andrew, Caldwell, Jeremy and Brinker, Achim (2009) A time-resolved fluorescence resonance energy transfer-based assay for DEN1 peptidase activity. Analytical Biochemistry, 390 (1). pp. 85-87. ISSN 1096-0309

Enz, Albert, Feuerbach, Dominik, Frederiksen, Mathias, Gentsch, Conrad, Hurth, Konstanze, Müller, Werner, Nozulak, Joachim and Roy, Bernard Lucien (2009) Gamma-lactams--a novel scaffold for highly potent and selective alpha 7 nicotinic acetylcholine receptor agonists. Bioorganic & Medicinal Chemistry Letters, 19 (5). pp. 1287-1291. ISSN 1464-3405

Ertl, Peter and Schuffenhauer, Ansgar (2009) Estimation of synthetic accessibility score of drug-like molecules based on molecular complexity and fragment contributions. Journal of Cheminformatics, 1 (1). p. 8. ISSN 17582946

Eshuis, S A, Jager, P L, Maguire, Paul, Jonkman, S, Dierckx, R A and Leenders, K L (2009) Direct comparison of FP-CIT SPECT and F-DOPA PET in patients with Parkinson's disease and healthy controls. European Journal of Nuclear Medicine and Molecular Imaging, 36 (3). pp. 454-462. ISSN 1619-7089

Ezan, Eric and Bitsch, Francis (2009) Critical comparison of mass spectrometry and immunoassays for the bioanalysis of therapeutic antibodies. BioAnalysis, 1 (8). pp. 1375-1388. ISSN 1757-6180


Fabian, Marc R, Mathonnet, Géraldine, Sundermeier, Thomas, Mathys, Hansruedi, Zipprich, Jakob T, Svitkin, Yuri V, Rivas, Fabiola, Jinek, Martin, Wohlschlegel, James, Doudna, Jennifer A, Chen, Chyi-Ying A, Shyu, Ann-Bin, Yates, John R, Hannon, Gregory J, Filipowicz, Witold, Duchaine, Thomas F and Sonenberg, Nahum (2009) Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-Dependent Deadenylation. Molecular Cell, 35 (6). pp. 868-880. ISSN 1097-2765

Favory, Jean-Jacques, Stec, Agnieszka, Gruber, Henriette, Rizzini, Luca, Oravecz, Attila, Funk, Markus, Albert, Andreas, Cloix, Catherine, Jenkins, Gareth I, Oakeley, Edward James, Seidlitz, Harald K, Nagy, Ferenc and Ulm, Roman (2009) Interaction of COP1 and UVR8 regulates UV-B-induced photomorphogenesis and stress acclimation in Arabidopsis. The EMBO Journal, 28 (5). pp. 591-601. ISSN 1460-2075

Fayard, Berengere, Bianchi, Fabrizio, Dey, Julien, Moreno, Eliza, Dyaffer, Sabrina, Hynes, Nancy and Monard, Denis (2009) The serine protease inhibitor protease nexin-1 controls mammary cancer metastasis through LRP-1-mediated MMP-9 expression. Cancer Research, 69 (14). pp. 5690-5698. ISSN 1538-7445

Fendt, Markus, Buerki, Hugo, Imobersteg, Stefan, Lingenhoehl, Kurt, Mcallister, Kevin, Orain, David, Uzunov, Doncho and Chaperon, Frederique (2009) Fear-reducing effects of intra-amygdala neuropeptide Y infusion in animal models of conditioned fear: an NPY Y1 receptor independent effect. Psychopharmacology, 206 (2). pp. 291-301. ISSN 0033-3158

Fendt, Markus, Buerki, Hugo, Imobersteg, Stefan, Van Der Putten, P. Herman, Mcallister, Kevin, Leslie, Julian, Shaw, David and Hölscher, Christian (2009) The effect of mGlu(8) deficiency in animal models of psychiatric diseases. Genes, Brain, and Behavior, 9 (1). pp. 33-44. ISSN 1601-1848

Fourcaudot, Elodie, Gambino, Frederic, Casassus, Guillaume, Poulain, Bernard, Humeau, Yann and Luethi, Andreas (2009) L-type voltage-dependent Ca(2+) channels mediate expression of presynaptic LTP in amygdala. Nature Neuroscience. ISSN 1546-1726

Francotte, Eric (2009) Enantioselective Chromatography: From its Emergence to its Successful Implementation in the Pharmaceutical Environment. Chimia, 63 (12). pp. 867-871. ISSN 0009-4293

Frank, C Andrew, Pielage, Jan and Davis, Graeme W (2009) A presynaptic homeostatic signaling system composed of the Eph receptor, ephexin, Cdc42, and CaV2.1 calcium channels. Neuron, 61 (4). pp. 556-569. ISSN 1097-4199

Freeman, Mark, Hardaker, Liz and Battram, Cliff (2009) Models of COPD induced by tobacco smoke. Animals in scientific procedures home office website.

Friedel, Anna M, Pike, Brietta L and Gasser, Susan (2009) ATR/Mec1: coordinating fork stability and repair. Current Opinion in Cell Biology, 21 (2). pp. 237-244. ISSN 1879-0410

Fumagalli, Stefano, Di Cara, Alessandro, Neb-Gulati, Arti, Natt, Francois, Schwemberger, Sandy, Hall, Jonathan, Babcock, George F, Bernardi, Rosa, Pandolfi, Pier Paolo and Thomas, George (2009) Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction. Nature Cell Biology, 11 (4). pp. 501-508. ISSN 1476-4679

Fumagalli, Stefano, Di Cara, Alessandro, Neb-Gulati, Arti, Natt, Francois, Schwemberger, Sandy, Hall, Jonathan, Babcock, George F, Bernardi, Rosa, Pandolfi, Pier Paolo and Thomas, George (2009) Absence of nucleolar disruption after impairment of 40S ribosome biogenesis reveals an rpL11-translation-dependent mechanism of p53 induction. Nature Cell Biology, 11 (4). pp. 501-508. ISSN 1476-4679


Gaidatzis, D, Jacobeit, K, Oakeley, Edward James and Stadler, MB (2009) Overestimation of alternative splicing caused by variable probe characteristics in exon arrays. Nucleic Acids Research. ISSN 1362-4962

Garcia-Echeverria, Carlos (2009) Protein and lipid kinase inhibitors as targeted anticancer agents of the Ras/Raf/MEK and PI3K/PKB pathways. Purinergic Signalling, 5 (1). pp. 117-125. ISSN 1573-9538

Gattiker, Alexandre, Hermida, Leandro, Liechti, Robin, Xenarios, Ioannis, Collin, Olivier, Rougemont, Jacques and Primig, Michael (2009) MIMAS 3.0 is a Multiomics Information Management and Annotation System. BMC Bioinformatics, 10. p. 151. ISSN 1471-2105

Geisse, Sabine (2009) Reflections on more than 10 years of TGE approaches. Protein Expression and Purification, 64 (2). pp. 99-107. ISSN 1096-0279

Georgieva, Anna, Evans, Dean Brent, Miller, Joel and Sing, Tobias (2009) Computational inference of gene expression signatures differentiating between breast cancers responsive or resistant to letrozole. Cancer Research, 69 (2 Supplement). p. 212. ISSN 0576-6656

Gogolla, Nadine, Galimberti, Ivan, Deguchi, Yuichi and Caroni, Pico (2009) Wnt signaling mediates experience-related regulation of synapse numbers and mossy fiber connectivities in the adult hippocampus. Neuron, 62 (4). pp. 510-525. ISSN 1097-4199

Gossert, Alvar, Henry, Christelle, Blommers, Marcel J.J., Jahnke, Wolfgang and Fernandez, Cesar (2009) Time efficient detection of protein-ligand interactions with the polarization optimized PO-WaterLOGSY NMR experiment. Journal of Biomolecular NMR, 43 (4). pp. 211-217. ISSN 1573-5001

Graf, Christine, Rovina, Philipp and Bornancin, Frederic (2009) A secondary assay for ceramide kinase inhibitors based on cell growth inhibition by short-chain ceramides. Analytical Biochemistry, 384 (1). pp. 166-169. ISSN 1096-0309

Gresko, Ekaterina, Ritterhoff, S, Sevilla-Perez, J, Roscic, Ana, Froebius, K, Kotevic, I, Vichalkovski, A, Hess, Daniel, Hemmings, Brian Arthur and Schmitz, M L (2009) PML tumor suppressor is regulated by HIPK2-mediated phosphorylation in response to DNA damage. Oncogene, 28 (5). pp. 698-708. ISSN 1476-5594

Groff, Dan, Thielges, Megan C, Cellitti, Susan, Schultz, Peter and Romesberg, Floyd E (2009) Efforts toward the direct experimental characterization of enzyme microenvironments: tyrosine100 in dihydrofolate reductase. Angewandte Chemie (International ed. in English), 48 (19). pp. 3478-3481. ISSN 1521-3773

Gromada, Jesper, Duttaroy, Alokesh and Rorsman, Patrik (2009) The insulin receptor talks to glucagon? Cell Metabolism, 9 (4). pp. 303-305. ISSN 1932-7420

Gruenewald, Jan, Hunt, Grady S, Dong, Liqun, Niessen, Frank, Wen, Ben, Tsao, Meng-Lin, Perera, Roshan, Kang, Mingchao, Laffitte, Bryan, Azarian, Sassan, Ruf, Wolfram, Nasoff, Marc, Lerner, Richard A, Schultz, Peter and Smider, Vaughn V (2009) Mechanistic studies of the immunochemical termination of self-tolerance with unnatural amino acids. Proceedings of the National Academy of Sciences of the United States of America, 106 (11). pp. 4337-4342. ISSN 1091-6490

Grzmil, Michal and Hemmings, Brian Arthur (2009) Deregulated signalling networks in human brain tumours. Biochimica et Biophysica Acta: Proteins & Proteomics, 1804 (3). pp. 476-483. ISSN 1570-9639

Gunduz, Mithat, Argikar, Upendra, Baeschlin, Daniel, Ferreira, Suzie, Hosagrahara, Vinayak and Harriman, Shawn (2009) Identification of a novel N-carbamoyl glucuronide: In vitro, In vivo and mechanistic studies. Drug Metabolism and Disposition, 38 (3). pp. 361-367. ISSN 0090-9556

Gut, Heinz, Dominici, Paola, Pilati, Stefania, Astegno, Alessandra, Petoukhov, Maxim V, Svergun, Dmitri I, Gruetter, Markus and Capitani, Guido (2009) A Common Structural Basis for pH- and Calmodulin-mediated Regulation in Plant Glutamate Decarboxylase. Journal of Molecular Biology. ISSN 1089-8638


Haacke, Annette, Fendrich, Gabriele, Ramage, Paul and Geiser, Martin (2009) Chaperone over-expression in Escherichia coli: apparent increased yields of soluble recombinant protein kinases are due mainly to soluble aggregates. Protein Expression and Purification, 64 (2). pp. 185-193. ISSN 1096-0279

Harker, Elizabeth A, Daniels, Douglas, Guarracino, Danielle A and Schepartz, Alanna (2009) Beta-peptides with improved affinity for hDM2 and hDMX. Bioorganic & Medicinal Chemistry, 17 (5). pp. 2038-2046. ISSN 1464-3391

Harten, Sarah K, Shukla, Deepa, Barod, Ravi, Hergovich, Alexander, Balda, Maria S, Matter, Karl, Esteban, Miguel A and Maxwell, Patrick H (2009) Regulation of renal epithelial tight junctions by the von Hippel-Lindau tumor suppressor gene involves occludin and claudin 1 and is independent of E-cadherin. Molecular Biology of the Cell, 20 (3). pp. 1089-1101. ISSN 1939-4586

Haseneder, Rainer, Kratzer, Stephan, Kochs, Eberhard, Höfelmann, Daniela, Auberson, Yves, Eder, Matthias and Rammes, Gerhard (2009) The xenon-mediated antagonism against the NMDA receptor is non-selective for receptors containing either NR2A or NR2B subunits in the mouse amygdala. European Journal of Pharmacology, 619 (1-3). p. 33. ISSN 00142999

Hassiepen, Ulrich, Doering, Klaus and Woelcke, Julian (2009) Fluorescence Lifetime Assays: A Smart Solution for Inhibitor Profiling on Protease Panels. Screening - Trends in Drug Discovery, 10 (4). pp. 11-13. ISSN 1611-6038

Hehlgans, Stephanie, Lange, Inga, Eke, Iris and Cordes, Nils (2009) 3D cell cultures of human head and neck squamous cell carcinoma cells are radiosensitized by the focal adhesion kinase inhibitor TAE226. Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology. ISSN 1879-0887

Heider, Ulrike, Kaiser, Martin, Mieth, Maren, Lamottke, Britta, Rademacher, Jessica, Jakob, Christian, Braendle, Edgar, Stover, David and Sezer, Orhan (2009) Serum concentrations of DKK-1 decrease in patients with multiple myeloma responding to anti-myeloma treatment. European Journal of Haematology, 82 (1). pp. 31-38. ISSN 1600-0609

Hemmings, Brian Arthur, Restuccia, David and Tonks, Nick (2009) Targeting the Kinome II. Current Opinion in Cell Biology, 21 (2). pp. 135-139. ISSN 1879-0410

Hergovich, Alexander and Hemmings, Brian Arthur (2009) Mammalian NDR/LATS protein kinases in hippo tumor suppressor signaling. BioFactors (Oxford, England). ISSN 0951-6433

Hergovich, Alexander, Kohler, Reto, Schmitz, Debora, Vichalkovski, Anton, Cornils, Hauke and Hemmings, Brian Arthur (2009) The MST1 and hMOB1 Tumor Suppressors Control Human Centrosome Duplication by Regulating NDR Kinase Phosphorylation. Current Biology, 19 (20). pp. 1692-1702. ISSN 1879-0445

Holloway, M. Katharine, Hunt, Peter and McGaughey, Georgia B. (2009) Structure and Modeling in the Design of b- and c-Secretase Inhibitors. Drug Development Research, 70 (2). pp. 70-93.

Hong, Lin, Quinn, Christopher and Jia, Yong (2009) Evaluating the utility of the HTRF Transcreener ADP assay technology: a comparison with the standard HTRF assay technology. Analytical Biochemistry, 391 (1). pp. 31-38. ISSN 1096-0309

Horstmann, S, Koziol, J A, Martinez-Torres, F, Nagel, S, Gardner, Humphrey and Wagner, S (2009) Sonographic monitoring of mass effect in stroke patients treated with hypothermia. Correlation with intracranial pressure and matrix metalloproteinase 2 and 9 expression. Journal of the Neurological Sciences, 276 (1-2). pp. 75-78. ISSN 0022-510X

Hotz, Hans-Rudolf and Peters, Antoine (2009) Protein demethylation required for DNA methylation. Nature Genetics, 41 (1). pp. 10-11. ISSN 1546-1718

Hu, Hongzhen, Bandell, Michael, Petrus, Matthew, Zhu, Michael X and Patapoutian, Ardem (2009) Zinc activates damage-sensing TRPA1 ion channels. Nature Chemical Biology, 5 (3). pp. 183-190. ISSN 1552-4469

Hu, Pei, Yin, Qi, Deckert-Salva, Fabienne, Jiang, Ji, Liu, Dongyang, Kjems, Lise, Dole, William and He, Yan-Ling (2009) Pharmacokinetics and pharmacodynamics of vildagliptin in healthy Chinese volunteers. Journal of Clinical Pharmacology, 49 (1). pp. 39-49. ISSN 0091-2700

Hu, Hongzhen, Grandl, Joerg, Bandell, Michael, Petrus, Matthew and Patapoutian, Ardem (2009) Two amino acid residues determine 2-APB sensitivity of the ion channels TRPV3 and TRPV4. Proceedings of the National Academy of Sciences of the United States of America, 106 (5). pp. 1626-1631. ISSN 1091-6490

Hu, Mei, Sun, Yong-Jun, Zhou, Qi-Gang, Auberson, Yves, Chen, Ling, Hu, Yao, Luo, Chun-Xia, Wu, Jia-Yi, Zhu, Dong-Ya and Li, Li-Xin (2009) Reduced spatial learning in mice treated with NVP-AAM077 through down-regulating neurogenesis. European Journal of Pharmacology, 622 (1-3). pp. 37-44. ISSN 00142999

Huang, Bing S, White, Roselyn A, Ahmad, Monir, Tan, Junhui, Jeng, Arco and Leenen, Frans H H (2009) Central infusion of aldosterone synthase inhibitor attenuates left ventricular dysfunction and remodelling in rats after myocardial infarction. Cardiovascular Research, 81 (3). pp. 574-581. ISSN 1755-3245

Huang, Shih-Min, Mishina, Yuji, Liu, Shanming, Cheung, Atwood, Stegmeier, Frank, Michaud, Gregory, Charlat, Olga, Wiellette, Elizabeth, Zhang, Yue, Wiessner, Stephanie, Hild, Marc, Shi, Xiaoying, Wilson, Christopher, Mickanin, Craig, Myer, Vic, Fazal, Aleem, Tomlinson, Ronald, Serluca, Fabrizio, Shao, Wenlin, Cheng, Hong, Shultz, Michael, Rau, Christina, Schirle, Markus, Schlegl, Judith, Ghidelli, Sonja, Fawell, Stephen, Lu, Chris, Curtis, Daniel, Kirschner, Marc W., Lengauer, Christoph, Finan, Peter, Tallarico, John, Bouwmeester, Antonius, Porter, Jeffrey, Bauer, Andreas and Cong, Feng (2009) Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling. Nature, 461 (7264). pp. 614-620. ISSN 0028-0836

Hublitz, Philip, Albert, Mareike and Peters, Antoine (2009) Mechanisms of transcriptional repression by histone lysine methylation. The International Journal of Developmental Biology, 53 (2-3). pp. 335-354. ISSN 1696-3547

Hugel, Sylvain, Abegg, Mathias, de Paola, Vincenzo, Caroni, Pico, Gaehwiler, Beat H and McKinney, R Anne (2009) Dendritic spine morphology determines membrane-associated protein exchange between dendritic shafts and spine heads. Cerebral Cortex, 19 (3). pp. 697-702. ISSN 1460-2199

Hyde, Damon, de Kleine, Ruben, Maclaurin, Sarah, Miller, Eric, Brooks, Dana H, Krucker, Thomas and Ntziachristos, Vasilis (2009) Hybrid FMT-CT imaging of amyloid-beta plaques in a murine Alzheimer's disease model. NeuroImage, 44 (4). pp. 1304-1311. ISSN 1095-9572

Hynes, Nancy and Dey, Julien H (2009) PI3K inhibition overcomes trastuzumab resistance: blockade of ErbB2/ErbB3 is not always enough. Cancer Cell, 15 (5). pp. 353-355. ISSN 1878-3686

Hynes, Nancy and Mac Donald, Gwen (2009) ErbB receptors and signaling pathways in cancer. Current Opinion in Cell Biology, 21 (2). pp. 177-184. ISSN 1879-0410

Hynes, Nancy E. and Stoelzle, Tina (2009) Key signalling nodes in mammary gland development and cancer: Myc. Breast Cancer Research, 11 (5). p. 210. ISSN 1465-5411


Irelan, Jeffrey, Gutierrez, Ana, Gutierrez, Able, Peters, Gordon, Quon, Kim, Miraglia, Loren and Chanda, Sumit (2009) A functional screen for regulators of CKDN2A reveals MEOX2 as a transcriptional activator of INK4a. Plos One, 4 (4). e5067-e5067. ISSN 1932-6203


Jacob, Sandra, Moebitz, Henrik and Fabbro, Doriano (2009) Structural biology contributions to tyrosine kinase drug discovery. Current Opinion in Cell Biology, 21 (2). pp. 280-287. ISSN 1879-0410

Jecklin, Matthias Conradin, Touboul, David, Jain, Rishi, Toole, Estee, Tallarico, John, Drueckes, Peter, Ramage, Paul and Zenobi, Renato (2009) Affinity classification of kinase inhibitors by mass spectrometric methods and validation using standard IC(50) measurements. Analytical Chemistry, 81 (1). pp. 408-419. ISSN 1520-6882

Jiang, Zhengjin, Reilly, John, Everatt, Brian and Smith, Norman W (2009) Novel zwitterionic polyphosphorylcholine monolithic column for hydrophilic interaction chromatography. Journal of Chromatography. A, 1216 (12). pp. 2439-2448. ISSN 1873-3778

Jones, Andy, Lister, Allyson L, Hermida, Leandro, Wilkinson, Peter, Eisenacher, Martin, Belhajjame, Khalid, Gibson, Frank, Lord, Phil, Pocock, Matthew, Rosenfelder, Heiko, Santoyo-Lopez, Javier, Wipat, Anil and Paton, Norman W (2009) Modeling and Managing Experimental Data Using FuGE. Omics : a Journal of Integrative Biology, 13 (3). pp. 239-251. ISSN 1557-8100


Kaiser, M, Lamottke, B, Mieth, M, Jensen, Michael Rugaard, Quadt, Cornelia, Garcia-Echeverria, Carlos, Atadja, Peter, Heider, U, von Metzler, I, Turkmen, S and Sezer, O (2009) Synergistic action of the novel HSP90 inhibitor NVP-AUY922 with histone deacetylase inhibitors, melphalan, or doxorubicin in multiple myeloma. European Journal of Haematology, 84 (4). pp. 337-344. ISSN 0902-4441

Kalb, Wolfgang L, Stassen, Arno F, Batlogg, Bertram, Berens, Ulrich, Schmidhalter, Beat, Bienewald, Frank, Hafner, Andreas and Wagner, Beatrix (2009) Quinoid heteropentacenes as promising organic semiconductors for field-effect transistor applications. Journal of Applied Physics, 105 (4). p. 43705. ISSN 0021-8979

Kallen, Joerg, Goepfert, Arnaud, Blechschmidt, Anke, Izaac, Aude, Geiser, Martin, Tavares, Gisele, Ramage, Paul, Furet, Pascal, Masuya, Keiichi and Lisztwan, Joanna (2009) Crystal Structures of Human MdmX (HdmX) in Complex with p53 Peptide Analogues Reveal Surprising Conformational Changes. The Journal of Biological Chemistry, 284 (13). pp. 8812-8821. ISSN 0021-9258

Kedrin, Dmitriy, Wyckoff, Jeffrey, Boimel, Pamela J, Coniglio, Salvatore J, Hynes, Nancy, Arteaga, Carlos L and Segall, Jeffrey E (2009) ERBB1 and ERBB2 have distinct functions in tumor cell invasion and intravasation. Clinical Cancer Research : an official journal of the American Association for Cancer Research, 15 (11). pp. 3733-3739. ISSN 1078-0432

Kilford, Peter, Stringer, Rowan, Sohal, Bindi, Houston, J Brian and Galetin, Aleksandra (2009) Prediction of drug clearance by glucuronidation from in vitro data: use of combined cytochrome P450 and UDP-glucuronosyltransferase cofactors in alamethicin-activated human liver microsomes. Drug Metabolism and Disposition: the Biological Fate of Chemicals, 37 (1). pp. 82-89. ISSN 1521-009X

King, J N, Dawson, J, Esser, Ronald, Fujimoto, Roger, Kimble, E F, Maniara, Wieslawa, Marshall, Paul, O'Byrne, L, Quadros, Elizabeth, Toutain, P L and Lees, P (2009) Preclinical pharmacology of robenacoxib: a novel selective inhibitor of cyclooxygenase-2. Journal of Veterinary Pharmacology and Therapeutics, 32 (1). pp. 1-17. ISSN 1365-2885

Klock, Heath and Lesley, Scott (2009) The Polymerase Incomplete Primer Extension (PIPE) method applied to high-throughput cloning and site-directed mutagenesis. Methods in Molecular Biology, 498. pp. 91-103. ISSN 1064-3745

Koda, Aya, Wakida, Naoki, Toriyama, Kazuhiro, Yamamoto, Kazutoshi, Iijima, Hiromi, Tomita, Kimio and Kitamura, Kenichiro (2009) Urinary prostasin in humans: relationships among prostasin, aldosterone and epithelial sodium channel activity. Hypertension Research : official journal of the Japanese Society of Hypertension, 32 (4). pp. 276-281. ISSN 1348-4214

Koehn, James and Hunt, Ian (2009) High-Throughput Protein Production (HTPP): a review of enabling technologies to expedite protein production. Methods in Molecular Biology (Clifton, N.J.), 498. pp. 1-18. ISSN 1064-3745

Korur, Serdar, Huber, Roland M, Sivasankaran, Balasubramanian, Petrich, Michael, Morin, Pier, Hemmings, Brian Arthur, Merlo, Adrian and Lino, Maria Maddalena (2009) GSK3beta Regulates Differentiation and Growth Arrest in Glioblastoma. PloS One, 4 (10). e7443. ISSN 1932-6203

Kudo, Nobuaki R, Anger, Martin, Peters, Antoine, Stemmann, Olaf, Theussl, Hans-Christian, Helmhart, Wolfgang, Kudo, Hiromi, Heyting, Christa and Nasmyth, Kim (2009) Role of cleavage by separase of the Rec8 kleisin subunit of cohesin during mammalian meiosis I. Journal of Cell Science, 122 (Pt 15). pp. 2686-9268. ISSN 0021-9533

Kuemmel, Anne, Gabriel, Daniela, Parker, Christian and Bender, Andreas (2009) Computational methods to support high-content screening: from compound selection and data analysis to postulating target hypotheses. Expert Opinion on Drug Discovery, 4 (1). pp. 5-13. ISSN 17460441

Kulathila, Raviraj, Vash, Brian, Sage, David, Cornell-Kennon, Susan, Wright, Kirk, Koehn, James, Stams, Travis, Clark, Kirk and Price, Allen (2009) The structure of the BIR3 domain of cIAP1 in complex with the N-terminal peptides of SMAC and caspase-9. Acta Crystallographica. Section D, Biological crystallography, 65 (Pt 1). pp. 58-66. ISSN 1399-0047

Kurz, Annemarie, Farlow, M and Lefevre, Gilbert (2009) Pharmacokinetics of a novel transdermal rivastigmine patch for the treatment of Alzheimer's disease: a review. International journal of clinical practice, 63 (5). pp. 799-805. ISSN 1742-1241

Kwak, Young-Shin, Kanter, Aaron, Wang, Bing and Liu, Yugang (2009) Efficient and convenient preparation of 3-aryl-2,2-dimethylpropanoates via Negishi coupling. Chemical Communications (Cambridge, England) (16). pp. 2145-2147. ISSN 1359-7345


Lane, Heidi, Wood, Jeanette, Mcsheehy, Paul M.J., Allegrini, Peter Roland, Boulay, Anne, Brueggen, Josef, Littlewood-Evans, Amanda, Maira, Sauveur-Michel, Martiny-Baron, Georg, Schnell, Christian, Sini, Patrizia and O'Reilly, Terence (2009) mTOR inhibitor RAD001 (everolimus) has antiangiogenic/vascular properties distinct from a VEGFR tyrosine kinase inhibitor. Clinical Cancer Research: an official journal of the American Association for Cancer Research, 15 (5). pp. 1612-1622. ISSN 1078-0432

Laurent, Didier, Gounarides, John, Gao, Jiaping and Boettcher, Brian (2009) Effects of cevoglitazar, a dual PPARalpha/gamma agonist, on ectopic fat deposition in fatty Zucker rats. Diabetes, Obesity & Metabolism, 11 (6). pp. 632-636. ISSN 1463-1326

Lee, Hyun Soo, Spraggon, Glen, Schultz, Peter and Wang, Feng (2009) Genetic Incorporation of a Metal-Ion Chelating Amino Acid into Proteins as a Biophysical Probe. Journal of the American Chemical Society, 131 (7). pp. 2481-2483. ISSN 1520-5126

Lee, Y P, Fleming, A J, Koerner, Ch and Meins, Frederick Jr. (2009) Differential expression of the CBF pathway and cell cycle-related genes in Arabidopsis accessions in response to chronic low-temperature exposure. Plant Biology (Stuttgart, Germany), 11 (3). pp. 273-283. ISSN 1435-8603

Lefeber, Dirk J, Schönberger, Johannes, Morava, Eva, Guillard, Mailys, Huyben, Karin M, Verrijp, Kiek, Grafakou, Olga, Evangeliou, Athanasios, Preijers, Frank W, Manta, Panagiota, Yildiz, Jef, Gruenewald, Stephanie, Spilioti, Martha, van den Elzen, Christa, Klein, Dominique, Hess, Daniel, Ashida, Hisashi, Hofsteenge, Jan, Maeda, Yusuke, van den Heuvel, Lambert, Lammens, Martin, Lehle, Ludwig and Wevers, Ron A (2009) Deficiency of Dol-P-Man synthase subunit DPM3 bridges the congenital disorders of glycosylation with the dystroglycanopathies. American Journal of Human Genetics, 85 (1). pp. 76-86. ISSN 1537-6605

Lefevre, Gilbert, Bueche, Monika, Sedek, Greg, Maton, Steve, Enz, Albert, Lorch, Ulrike, Sagan, Cyriaque and Appel Dingemanse, Silke (2009) Similar rivastigmine pharmacokinetics and pharmacodynamics in Japanese and white healthy participants following the application of novel rivastigmine patch. Journal of clinical pharmacology, 49 (4). pp. 430-443. ISSN 0091-2700

Lerchner, Andreas, Machauer, Rainer, Betschart, Claudia, Veenstra, Siem, Rueeger, Heinrich, Mccarthy, Clive, Tintelnot-Blomley, Marina, Jaton, Anne-Lise, Rabe, Sabine, Desrayaud, Sandrine, Enz, Albert, Staufenbiel, Matthias, Paganetti, Paolo, Rondeau, Jean-Michel and Neumann, Ulf (2009) Macrocyclic BACE-1 Inhibitors Acutely Reduce Abeta in Brain after po Application. Bioorganic and Medicinal Chemistry Letters, 20 (2). pp. 603-607. ISSN 0960-894X

Lewis, Zachary A, Honda, Shinji, Khlafallah, Tamir K, Jeffress, Jennifer K, Freitag, Michael, Mohn, Fabio, Schuebeler, Dirk and Selker, Eric U (2009) Relics of repeat-induced point mutation direct heterochromatin formation in Neurospora crassa. Genome Research, 19 (3). pp. 427-437. ISSN 1088-9051

Li, Wenkui and Tse, Francis (2009) Dried blood spot sampling in combination with LC-MS/MS for quantitative analysis of small molecules. Biomedical Chromatography, 24 (1). pp. 49-65. ISSN 0269-3879

Ling, Daijun, Song, Ho-Juhn, Garza, Dan, Neufeld, Thomas P and Salvaterra, Paul M (2009) Abeta42-induced neurodegeneration via an age-dependent autophagic-lysosomal injury in Drosophila. PloS ONE, 4 (1). e4201. ISSN 1932-6203

Loedige, Inga and Filipowicz, Witold (2009) TRIM-NHL proteins take on miRNA regulation. Cell, 136 (5). pp. 818-820. ISSN 1097-4172

Lombardi, Dario, Cuenoud, Bernard, Wunderli-Allenspach, Heidi and Krämer, Stefanie D (2009) Interaction kinetics of salmeterol with egg phosphatidylcholine liposomes by surface plasmon resonance. Analytical Biochemistry, 385 (2). pp. 215-223. ISSN 1096-0309

Lombardi, Dario, Cuenoud, Bernard, Kramer, Stephanie D and Trifilieff, Alexandre (2009) Lipid membrane interactions of indacaterol and salmeterol: do they influence their pharmacological properties? European Journal of Pharmaceutical Sciences, 38 (5). pp. 533-547. ISSN 0928-0987

Lyssiotis, Costas A, Foreman, Ruth K, Staerk, Judith, Garcia, Michael, Mathur, Divya, Markoulaki, Styliani, Hanna, Jacob, Lairson, Luke L, Charette, Bradley D, Bouchez, Laure C, Bollong, Michael, Kunick, Conrad, Brinker, Achim, Cho, Charles, Schultz, Peter and Jaenisch, Rudolf (2009) Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4. Proceedings of the National Academy of Sciences of the United States of America, 106 (22). pp. 8912-8917. ISSN 1091-6490


Machauer, Rainer, Laumen, Kurt, Veenstra, Siem, Rondeau, Jean-Michel, Tintelnot-Blomley, Marina, Betschart, Claudia, Jaton, Anne-Lise, Desrayaud, Sandrine, Staufenbiel, Matthias, Rabe, Sabine, Paganetti, Paolo and Neumann, Ulf (2009) Macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors with activity in vivo. Bioorganic & Medicinal Chemistry Letters, 19 (5). pp. 1366-1370. ISSN 1464-3405

Machauer, Rainer, Veenstra, Siem, Rondeau, Jean-Michel, Tintelnot-Blomley, Marina, Betschart, Claudia, Neumann, Ulf and Paganetti, Paolo (2009) Structure-based design and synthesis of macrocyclic peptidomimetic beta-secretase (BACE-1) inhibitors. Bioorganic & Medicinal Chemistry Letters, 19 (5). pp. 1361-1365. ISSN 1464-3405

Madan, Vikas, Madan, Babita, Brykczynska, Urszula, Zilbermann, Frederic, Hogeveen, Kevin, Doehner, Konstanze, Doehner, Hartmut, Weber, Odile, Blum, Carmen, Rodewald, Hans-Reimer, Sassone-Corsi, Paolo, Peters, Antoine and Fehling, Hans Joerg (2009) Impaired function of primitive hematopoietic cells in mice lacking the Mixed-Lineage-Leukemia homolog MLL5. Blood, 113 (7). pp. 1444-1454. ISSN 1528-0020

Maira, Sauveur-Michel, Stauffer, Frederic, Schnell, Christian and Garcia-Echeverria, Carlos (2009) PI3K inhibitors for cancer treatment: where do we stand? Biochemical Society Transactions, 37 (Pt 1). pp. 265-272. ISSN 1470-8752

Malyala, Padma, O'Hagan, Derek T and Singh, Manmohan (2009) Enhancing the therapeutic efficacy of CpG oligonucleotides using biodegradable microparticles. Advanced Drug Delivery Reviews, 61 (3). pp. 218-225. ISSN 1872-8294

Marmor, M F, Fulton, A B, Holder, G E, Miyake, Y, Brigell, Mitchell and Bach, M (2009) ISCEV Standard for full-field clinical electroretinography (2008 update). Documenta Ophthalmologica, 118 (1). pp. 69-77. ISSN 1573-2622

Martin-Subero, Jose I, Kreuz, Markus, Bibikova, Marina, Bentink, Stefan, Ammerpohl, Ole, Wickham-Garcia, Eliza, Rosolowski, Maciej, Richter, Julia, Lopez-Serra, Lidia, Ballestar, Esteban, Berger, Hilmar, Agirre, Xabier, Bernd, Heinz-Wolfram, Calvanese, Vincenzo, Cogliatti, Sergio B, Drexler, Hans G, Fan, Jian-Bing, Fraga, Mario F, Hansmann, Martin L, Hummel, Michael, Klapper, Wolfram, Korn, Bernhard, Kueppers, Ralf, Macleod, Roderick A F, Moeller, Peter, Ott, German, Pott, Christiane, Prosper, Felipe, Rosenwald, Andreas, Schwaenen, Carsten, Schuebeler, Dirk, Seifert, Marc, Stuerzenhofecker, Benjamin, Weber, Michel, Wessendorf, Swen, Loeffler, Markus, Truemper, Lorenz, Stein, Harald, Spang, Rainer, Esteller, Manel, Barker, David, Hasenclever, Dirk and Siebert, Reiner (2009) New insights into the biology and origin of mature aggressive B-cell lymphomas by combined epigenomic, genomic, and transcriptional profiling. Blood, 113 (11). pp. 2488-2497. ISSN 1528-0020

Martino, Fabrizio, Kueng, Stephanie, Robinson, Philip, Tsai-Pflugfelder, Monika, van Leeuwen, Fred, Ziegler, Mathias, Cubizolles, Fabien, Cockell, Moira M, Rhodes, Daniela and Gasser, Susan (2009) Reconstitution of yeast silent chromatin: multiple contact sites and O-AADPR binding load SIR complexes onto nucleosomes in vitro. Molecular Cell, 33 (3). pp. 323-334. ISSN 1097-4164

Marwick, John, Caramori, Gaetano, Stevenson, Christopher, Casolari, Paolo, Jazrawi, Elen, Barnes, Peter J, Ito, Kazuhiro, Adcock, Ian M, Kirkham, Paul and Papi, Alberto (2009) Inhibition of PI3Kdelta restores glucocorticoid function in smoking-induced airway inflammation in mice. American Journal of Respiratory and Critical Care Medicine, 179 (7). pp. 542-548. ISSN 1535-4970

Matsuda, Yutaka, Schlange, Thomas, Oakeley, Edward James, Boulay, Anne and Hynes, Nancy (2009) WNT signaling enhances breast cancer cell motility and blockade of the WNT pathway by sFRP1 suppresses MDA-MB-231 xenograft growth. Breast Cancer Research : BCR, 11 (3). R32. ISSN 1465-542X

Mauss, Alex, Tripodi, Marco, Evers, Jan Felix and Landgraf, Matthias (2009) Midline Signalling Systems Direct the Formation of a Neural Map by Dendritic Targeting in the Drosophila Motor System. PLoS Biology, 7 (9). e1000200. ISSN 1544-9173

Mayr, Lorenz and Bojanic, Dejan (2009) Novel Trends in High-Throughput Screening. Current Opinion in Pharmacology, 9 (5). pp. 580-588. ISSN 1471-4892

McCarthy, Jeanette J, Somji, Aleefia, Weiss, Lauren A, Steffy, Brian, Vega, Raquel, Barrett-Connor, Elizabeth, Talavera, Gregory and Glynne, Richard (2009) Polymorphisms of the Scavenger Receptor Class B Member 1 Are Associated with Insulin Resistance with Evidence of Gene by Sex Interaction. The Journal of Clinical Endocrinology and Metabolism, 94 (5). pp. 1789-1796. ISSN 1945-7197

Meder, Benjamin, Laufer, Christina, Hassel, David, Just, Steffen, Marquart, Sabine, Vogel, Britta, Hess, Alexander, Fishman, Mark, Katus, Hugo A and Rottbauer, Wolfgang (2009) A single serine in the carboxyl terminus of cardiac essential myosin light chain-1 controls cardiomyocyte contractility in vivo. Circulation Research, 104 (5). pp. 650-659. ISSN 1524-4571

Meira, Maria, Masson, Regis, Stagljar, Igor, Lienhard, Susanne, Maurer, Francisca, Boulay, Anne and Hynes, Nancy (2009) Memo is a cofilin-interacting protein that influences PLC{gamma}1 and cofilin activities, and is essential for maintaining directionality during ErbB2-induced tumor-cell migration. Journal of Cell Science, 122 (Pt 6). pp. 787-797. ISSN 0021-9533

Meisner, Nicole-Claudia, Hintersteiner, Martin, Seifert, Jan-Marcus, Bauer, Roman, Benoit, Roger, Widmer, Armin, Schindler, Torsten, Uhl, Volker, Lang, Michaela, Gstach, Hubert and Auer, Manfred (2009) Terminal adenosyl transferase activity of posttranscriptional regulator HuR revealed by confocal on-bead screening. Journal of Molecular Biology, 386 (2). pp. 435-450. ISSN 1089-8638

Miller, Andrew, Beisner, Daniel R, Liu, Daorong and Cooke, Michael (2009) Inositol 1,4,5-trisphosphate 3-kinase B is a negative regulator of BCR signaling that controls B cell selection and tolerance induction. Journal of Immunology, 182 (8). pp. 4696-4704. ISSN 1550-6606

Miller, T. W., Perez-Torres, M., Narasanna, A., Guix, M., Stal, O., Perez-Tenorio, G., Gonzalez-Angulo, A. M., Hennessy, B. T., Mills, G. B., Kennedy, J. P., Lindsley, C. W. and Arteaga, C. L. (2009) Loss of Phosphatase and Tensin Homologue Deleted on Chromosome 10 Engages ErbB3 and Insulin-Like Growth Factor-I Receptor Signaling to Promote Antiestrogen Resistance in Breast Cancer. Cancer Research, 69 (10). pp. 4192-4201. ISSN 0008-5472

Miller-Moslin, Karen, Peukert, Stefan, Mcewan, Michael, Karki, Rajesh, Llamas, Luis, Yusuff, Naeem, Dai, Miao, Perez, Lawrence, Michael, Walter, Sheng, Tao, Williams, Juliet, Dorsch, Marion, Bourret, Aaron, Ramamurthy, Arun, Yuan, Jing, Guo, Ribo, Matsumoto, Melissa, Vattay, Anthony, Maniara, Wieslawa, Amaral, Adam and Kelleher Iii, Joseph (2009) 1-Amino-4-benzylphthalazines as novel, orally bioavailable Smoothened antagonists with anti-tumor activity. Journal of Medicinal Chemistry, 52 (13). pp. 3954-3968.

Minoux, Maryline, Antonarakis, Gregory S, Kmita, Marie, Duboule, Denis and Rijli, Filippo M (2009) Rostral and caudal pharyngeal arches share a common neural crest ground pattern. Development (Cambridge, England), 136 (4). pp. 637-645. ISSN 0950-1991

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Varela Sanz, Maria Elisa, Shimada, Kenji, Laroche, Thierry, Leroy, Didier and Gasser, Susan (2009) Lte1, Cdc14 and MEN-controlled Cdk inactivation in yeast coordinate rDNA decompaction with late telophase progression. The EMBO Journal, 28 (11). pp. 1562-1575. ISSN 1460-2075

Velcicky, Juraj, Feifel, Roland, Hawtin, Stuart, Heng, Richard, Huppertz, Christine, Koch, Guido, Kroemer, Markus, Moebitz, Henrik, Revesz, Laszlo, Scheufler, Clemens and Schlapbach, Achim (2009) Novel 3-Aminopyrazole Inhibitors of MK-2 Discovered by Scaffold Hopping Strategy. Bioorganic and Medicinal Chemistry Letters, 20 (3). pp. 1293-1297. ISSN 0960-894X

Venkatesan, Kavitha, Rual, Jean-François, Vazquez, Alexei, Stelzl, Ulrich, Lemmens, Irma, Hirozane-Kishikawa, Tomoko, Hao, Tong, Zenkner, Martina, Xin, Xiaofeng, Goh, Kwang-Il, Yildirim, Muhammed A, Simonis, Nicolas, Heinzmann, Kathrin, Gebreab, Fana, Sahalie, Julie M, Cevik, Sebiha, Simon, Christophe, de Smet, Anne-Sophie, Dann, Elizabeth, Smolyar, Alex, Vinayagam, Arunachalam, Yu, Haiyuan, Szeto, David, Borick, Heather, Dricot, Amélie, Klitgord, Niels, Murray, Ryan R, Lin, Chenwei, Lalowski, Maciej, Timm, Jan, Rau, Kirstin, Boone, Charles, Braun, Pascal, Cusick, Michael E, Roth, Frederick P, Hill, David E, Tavernier, Jan, Wanker, Erich E, Barabási, Albert-László and Vidal, Marc (2009) An empirical framework for binary interactome mapping. Nature Methods, 6 (1). pp. 83-90. ISSN 1548-7105

Villagra, Alejandro, Cheng, Fengdong, Wang, Hong-Wei, Suarez, Ildelfonso, Glozak, Michelle, Maurin, Michelle, Nguyen, Danny, Wright, Kenneth L, Atadja, Peter, Bhalla, Kapil, Pinilla-Ibarz, Javier, Seto, Edward and Sotomayor, Eduardo M (2009) The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance. Nature Immunology, 10 (1). pp. 92-100. ISSN 1529-2916

Vulpetti, Anna, Hommel, Ulrich, Landrum, Gregory, Lewis, Richard and Dalvit, Claudio (2009) Design and NMR-Based Screening of LEF, a Library of Chemical Fragments with Different Local Environment of Fluorine. Journal of the American Chemical Society, 131 (36). pp. 12949-12959. ISSN 1520-5126


Wang, Jing, Hevi, Sarah, Kurash, Julia K, Lei, Hong, Gay, Frédérique, Bajko, Jeffrey, Su, Hui, Sun, Weitao, Chang, Hua, Xu, Guoliang, Gaudet, Francois, Li, En and Chen, Taiping (2009) The lysine demethylase LSD1 (KDM1) is required for maintenance of global DNA methylation. Nature Genetics, 41 (1). pp. 125-129. ISSN 1546-1718

Wang, Weidong, Walker, John, Wang, Xia, Tremblay, Matthew, Lee, Jae Wook, Wu, Xu and Schultz, Peter (2009) Identification of small-molecule inducers of pancreatic beta-cell expansion. Proceedings of the National Academy of Sciences of the United States of America, 106 (5). pp. 1427-1432. ISSN 1091-6490

Wang, Jianling and Tilton, Suzanne (2009) Mitigating Permeability and Absorption Risks in Drug Discovery. Expert Opinion on Drug Metabolism & Toxicology, 6 (2). pp. 171-187. ISSN 1742-5255

Weitz Schmidt, Gabriele, Chreng, Stephanie and Riek, Simone (2009) Allosteric LFA-1 inhibitors modulate natural killer cell function. Molecular Pharmacology, 75 (2). pp. 355-362. ISSN 1521-0111

Wiederschain, Dmitri, Wee, Susan, Chen, Lin, Loo, Alice, Yang, Guizhi, Huang, Alan, Chen, Yan, Caponigro, Giordano, Yao, Yung-Mae, Lengauer, Christoph, Sellers, William and Benson, John (2009) Single-vector inducible lentiviral RNAi system for oncology target validation. Cell Cycle, 8 (3). pp. 498-504. ISSN 1538-4101

Wiegert, J Simon, Hofmann, Frank, Bading, Hilmar and Bengtson, C Peter (2009) A transcription-dependent increase in miniature EPSC frequency accompanies late-phase plasticity in cultured hippocampal neurons. BMC neuroscience, 10. p. 124. ISSN 1471-2202

Wikoff, William R, Anfora, Andrew, Liu, Jun, Schultz, Peter, Lesley, Scott, Peters, Eric and Siuzdak, Gary (2009) Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites. Proceedings of the National Academy of Sciences of the United States of America, 106 (10). pp. 3698-3703. ISSN 1091-6490

Wollscheid, Bernd, Bausch-Fluck, Damaris, Henderson, Christine, O'Brien, Robert, Bibel, Miriam, Schiess, Ralph, Aebersold, Ruedi and Watts, Julian D (2009) Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins. Nature Biotechnology, 27 (4). pp. 378-386. ISSN 1546-1696

Wu, Meilin, Hesse, Eric, Morvan, Frederic, Zhang, Jian-Ping, Correa, Diego, Rowe, Glenn C, Kiviranta, Riku, Neff, Lynn, Philbrick, William M, Horne, William C and Baron, Roland (2009) Zfp521 antagonizes Runx2, delays osteoblast differentiation in vitro, and promotes bone formation in vivo. Bone, 44 (4). pp. 528-536. ISSN 1873-2763


Yaksi, Emre, von Saint Paul, Francisca, Niessing, Joern, Bundschuh, Sebastian T and Friedrich, Rainer W (2009) Transformation of odor representations in target areas of the olfactory bulb. Nature Neuroscience, 12 (4). pp. 474-482. ISSN 1546-1726

Yamamoto, Masamichi, Beppu, Hideyuki, Takaoka, Katsuyoshi, Meno, Chikara, Li, En, Miyazono, Kohei and Hamada, Hiroshi (2009) Antagonism between Smad1 and Smad2 signaling determines the site of distal visceral endoderm formation in the mouse embryo. Journal of Cell Biology, 184 (2). pp. 323-334. ISSN 1540-8140

Yen, Chi-Liang Eric, Cheong, Mei-Leng, Grueter, Carrie, Zhou, Ping, Moriwaki, Junya, Wong, Jinny S, Hubbard, Brian, Marmor, Stephen and Farese, Robert V (2009) Deficiency of the intestinal enzyme acyl CoA:monoacylglycerol acyltransferase-2 protects mice from metabolic disorders induced by high-fat feeding. Nature Medicine, 15 (4). pp. 442-446. ISSN 1546-170X

Yokthongwattana, Chotika, Bucher, Etienne, Caikovski, Marian, Vaillant, Isabelle, Nicolet, Joël, Mittelsten Scheid, Ortrun and Paszkowski, Jerzy (2009) MOM1 and Pol-IV/V interactions regulate the intensity and specificity of transcriptional gene silencing. EMBO Journal, 29 (2). pp. 340-351. ISSN 0261-4189


Zecri, Frederic, Albert, Rainer, Landrum, Gregory, Hinterding, Klaus, Cooke, Nigel Graham, Guerini, Danilo, Streiff, Markus, Bruns, Christian and Nuesslein-Hildesheim, Barbara (2009) Pyrazole derived from (+)-3-Carene; a Novel Potent and Selective Scaffold for Sphingosine-1-Phosphate (S1P1) Receptor Agonists. Bioorganic & Medicinal Chemistry Letters, 20 (1). pp. 35-37. ISSN 1464-3405

Zhu, Shoutian, Wurdak, Heiko, Wang, Jian, Lyssiotis, Costas A, Peters, Eric, Cho, Charles, Wu, Xu and Schultz, Peter (2009) A small molecule primes embryonic stem cells for differentiation. Cell Stem Cell, 4 (5). pp. 416-426. ISSN 1875-9777

Zipprich, Jakob T, Bhattacharyya, Sankar, Mathys, Hansruedi and Filipowicz, Witold (2009) Importance of the C-terminal domain of the human GW182 protein TNRC6C for translational repression. RNA (New York, N.Y.), 15 (5). pp. 781-793. ISSN 1469-9001

This list was generated on Wed Apr 17 04:40:28 2024 UTC.


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