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The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report

Azziz, R and Carmina, E and Dewailly, D and Diamanti-Kandarakis, E and Escobar-Morreale, H F and Futterweit, W and Janssen, O E and Legro, R S and Norman, R J and Taylor, Ann and Witchel, S F (2009) The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report. Fertility and Sterility, 91 (2). pp. 456-488.

Abstract

Objective: To review all available data and recommend a definition for polycystic ovary syndrome (PCOS) based
on published peer-reviewed data, whether already in use or not, to guide clinical diagnosis and future research.
Design: Literature review and expert consensus.
Setting: Professional society.
Patients: None.
Intervention(s): None.
Main Outcome Measure(s): A systematic review of the published peer-reviewed medical literature, by querying
MEDLINE databases, to identify studies evaluating the epidemiology or phenotypic aspects of PCOS.
Result(s): The Task Force drafted the initial report, following a consensus process via electronic communication,
which was then reviewed and critiqued by the Androgen Excess and PCOS (AE-PCOS) Society AE-PCOS Board
of Directors. No section was finalized until all members were satisfied with the contents, and minority opinions
noted. Statements were not included that were not supported by peer-reviewed evidence.
Conclusion(s): Based on the available data, it is the view of the AE-PCOS Society Task Force that PCOS should be
defined by the presence of hyperandrogenism (clinical and/or biochemical), ovarian dysfunction (oligo-anovulation
and/or polycystic ovaries), and the exclusion of related disorders. However, a minority considered the possibility
that there may be forms of PCOS without overt evidence of hyperandrogenism, but recognized that more data
are required before validating this supposition. Finally, the Task Force recognized and fully expects that the definition
of this syndrome will evolve over time to incorporate new research findings.

Item Type: Article
Related URLs:
Keywords: Polycystic ovary syndrome; hirsutism; menstrual dysfunction; phenotype; criteria
Related URLs:
Date Deposited: 14 Dec 2009 13:48
Last Modified: 14 Dec 2009 13:48
URI: https://oak.novartis.com/id/eprint/1609

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