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Population pharmacokinetics and optimal design of paediatric studies for famciclovir.

Ogungbenro, Kayode and Matthews, Ivan and Looby, Michael and Kaiser, Guenther and Graham, Gordon and Aarons, Leon (2009) Population pharmacokinetics and optimal design of paediatric studies for famciclovir. British Journal of Clinical Pharmacology, 68 (4). pp. 546-560. ISSN 1365-2125

Abstract

To develop a population pharmacokinetic model for penciclovir (famciclovir is a prodrug of penciclovir) in adults and children and suggest an appropriate dose for children. Furthermore, to develop a limited sampling design based on sampling windows for three different paediatric age groups (1-2, 2-5 and 5-12 years) using an adequate number of subjects for future pharmacokinetic studies.

Item Type: Article
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Date Deposited: 22 Jan 2011 00:45
Last Modified: 01 Feb 2013 00:47
URI: https://oak.novartis.com/id/eprint/4280

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