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Deferasirox does not induce QT/QTc-prolongation in healthy subjects.

Sechaud, Romain and Dumortier, Thomas and Balez, Sebastien (2009) Deferasirox does not induce QT/QTc-prolongation in healthy subjects. International journal of clinical pharmacology and therapeutics, 47 (5). pp. 321-327. ISSN 0946-1965

Abstract

The International Conference on Harmonization (ICH) E14 guidance recommends that almost all drugs should undergo careful clinical testing in a thorough QT/QTc study. Deferasirox (Exjade, ICL670) is a once-daily oral iron chelator, developed for the treatment of blood transfusion-related iron overload.

Item Type: Article
Date Deposited: 28 Jan 2012 00:45
Last Modified: 01 Feb 2013 00:46
URI: https://oak.novartis.com/id/eprint/5502

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