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Amygdala inhibitory circuits and the control of fear memory.

Ehrlich, Ingrid, Humeau, Yann, Grenier, François, Ciocchi, Stephane, Herry, Cyril and Luethi, Andreas (2009) Amygdala inhibitory circuits and the control of fear memory. Neuron, 62 (6). pp. 757-771. ISSN 1097-4199


Classical fear conditioning is a powerful behavioral paradigm that is widely used to study the neuronal substrates of learning and memory. Previous studies have clearly identified the amygdala as a key brain structure for acquisition and storage of fear memory traces. Whereas the majority of this work has focused on principal cells and glutamatergic transmission and its plasticity, recent studies have started to shed light on the intricate roles of local inhibitory circuits. Here, we review current understanding and emerging concepts of how local inhibitory circuits in the amygdala control the acquisition, expression, and extinction of conditioned fear at different levels.

Item Type: Article
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Additional Information: author can archive post-print (ie final draft post-refereeing); Publisher's version/PDF cannot be used
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Date Deposited: 14 Dec 2009 13:49
Last Modified: 31 Jan 2013 01:00


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