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Efficient and convenient preparation of 3-aryl-2,2-dimethylpropanoates via Negishi coupling

Kwak, Young-Shin and Kanter, Aaron and Wang, Bing and Liu, Yugang (2009) Efficient and convenient preparation of 3-aryl-2,2-dimethylpropanoates via Negishi coupling. Chemical Communications (Cambridge, England) (16). pp. 2145-2147. ISSN 1359-7345

Abstract

An efficient and convenient Negishi coupling protocol was developed for the preparation of 3-aryl-2,2-dimethylpropanoates providing easy access to key pharmaceutical intermediates that often require multi-step synthesis using conventional enolate chemistry.

Item Type: Article
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Additional Information: Author can archive post-print (ie final draft post-refereeing); Author's version in web repository after 12 months or immediately with fee
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Date Deposited: 22 Feb 2010 11:49
Last Modified: 22 Feb 2010 11:49
URI: https://oak.novartis.com/id/eprint/1851

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