Ménard, Joël, Watson, Catherine, Rigel, Dean, Jeng, Arco Y., Liang, Guiqing, Rebello, Sam, Zhang, Yiming, Dole, William, Fu, Fumin, Beil, Michael, Liu, Jing, Chen, Wei, Hu, Chii-Whei, Leung-Chu, Jennifer and LaSala, Daniel (2015) Aldosterone synthase inhibition: cardiorenal protection in animal disease models and translation of hormonal effects to human subjects. Journal of Translational Medicine.

A

Altmann, Eva, Grosche, Philipp, Sirockin, Finton, Mac Sweeney, Aengus, Ramage, Paul, Erbel, Paulus, Melkko, Samu, Bernardi, Anna, Hughes, Nicola, Ellis, David and Jarrousse Coscoy, Nadine (2015) Structure-based design and optimization of potent inhibitors of the adenoviral protease. Structure-based design and optimization of potent inhibitors of the adenoviral protease, 25 (3). pp. 438-443. ISSN 0960-894X

Alzahrani, Mohammad M., Makhdom , Asim M., Rauch, Frank, Lauzier, Dominique, Kotsiopriftis, Maria and Hamdy, Reggie C. (2015) Assessment of the Effect of Systemic Delivery of Sclerostin Antibodies on WNT Signaling in Distraction Osteogenesis Using Immunohistochemistry. Journal of orthopaedic research.

Ammann, P, Zacchetti, G, Gasser, Juerg Andreas, Lavet, C and Rizzoli, R (2015) Protein malnutrition attenuates bone anabolic response to PTH in female rats. Endocrinology.

Annan, Kofi, Ekuadzi, Edmund, Asare, Cindy, Sarpong, Kwane, Pistorius, Dominik, Oberer, Lukas, Gyan, Ben A. and Ofori, Michael (2015) Antiplasmodial Constituents from the Stem Bark of Polyalthia longifolia var Pendula. Phytochemistry Letters, 11. pp. 28-31.

April, Myriam, Daniels, Thomas, Forster, Cornelia, Jain, Monish, Kanter, Aaron, Li, Jingzhou, Streeper, Ryan, Wang, Bing, Brewer, Jason, Gilmore, Thomas, Kwak, Youngshin, Serrano-Wu, Michael, Szklennik, Paul, Thompson, James and McQuire , Les (2015) Discovery of diamide compounds as diacylglycerol acyltransferase 1 (DGAT1) inhibitors. Bioorganic and medicinal chemistry letters, 26 (4). pp. 1245-1248. ISSN 0960894X

Arduin, Elodie, Arora, Seguinde, Bamert, Paulo Roky, Kuiper, Torsten, Popp, Simone, Geisse, Sabine, Grau, Roger, Calzascia, Thomas, Zenke, Gerhard and Kovarik, Jiri (2015) Highly reduced binding to high and low affinity mouse Fc gamma receptors by L234A/L235A and N297A Fc mutations engineered into mouse IgG2a. Molecular Immunology, 63 (2). pp. 456-463.

Arias, HR, Feuerbach, Dominik and Ortells, Marcelo (2015) Functional and Structural Interaction of (-)-Lobeline with human α4β2 and α4β4 Nicotinic Acetylcholine Receptor Subtypes. Int. J. Biochem. Cell Bio.

Arias, HR, Targowska-Duda, KM, Feuerbach, Dominik and Jozwiak, K (2015) The antidepressant-like activity of nicotine, but not 3-furan-2-yl-N-p-tolyl-acrylamide, is regulated by the nicotinic receptor β4 subunit. Neuroscience letter.

Arias, Hugo R, Targowska-Duda, Katarzyna M, Feuerbach, Dominik and Jozwiak, Krzysztof (2015) Coronaridine congeners inhibit human α3β4 Nicotinic Acetylcholine Receptors by interacting with luminal and non-luminal sites. Biochemistry.

Arista, Luca, Renier , van der Westhuyzena, Susan, Winks, Colin, Wilson, Grant, Boyle, Richard, Gessner, Candice, Soares de Melo, Dale, Taylor, Carmen, de Kock, Mathew, Njoroge, Christel, Brunschwig, Nina, Lawrence, Frik, Sirgel, Paul, van Helden, Ronnett, Seldon, Atica, Moose, Digby, Warner, Ujjini , Manjunatha, Paul, Smith, Leslie, Street and Kelly, Chibale (2015) Pyrrolo[3,4-c]pyridine-1,3(2H)-diones: A new anti-mycobacterial class that targets mycobacterial energy metabolism. Pyrrolo[3,4-c]pyridine-1,3(2H)-diones: A new anti-mycobacterial class that targets mycobacterial energy metabolism, 58 (23). pp. 9371-9381. ISSN 0022-26231520-4804

Ashok, Y, Nanekar, R and Jaakola, V-P (2015) Defining thermostability of membrane proteins by western blotting. Protein engineering, design & selection : PEDS, 28 (12). pp. 539-542. ISSN 1741-0134

Asmus, Lutz R., Grimshaw, John, Richle, Philipp, Eicher, Barbara, Urech, David M., Gurny, Robert and Moeller, Michael (2015) Injectable Formulations for an Intravitreal Sustained-Release Application of a Novel Single-Chain VEGF Antibody Fragment. European Journal of Pharmaceutics and Biopharmaceutics, 95 (Part B). pp. 250-260. ISSN 0939-6411

Auld, Douglas and Jimenez, Marta (2015) Examining Ligand-based Stabilization of Proteins in Cells with MEK1 Kinase Inhibitors. Assay and Drug Development Technologies, 13 (5). pp. 266-276. ISSN 1540-658X1557-8127

Auld, Douglas, Wassermann, Anne and Camargo, Miguel (2015) Composition and applications of focus libraries to phenotypic assays. Frontiers in Pharmacology, 5. ISSN 1663-9812

Awan, Zuhier, Denis, Maxime, Awan, Amani, Gram, Hermann, Seidah, Nabil and Genest, Jaques (2015) Inhibition of Interleukin-1β by a Monoclonal Antibody Therapy Reduces Vascular Calcification in Ldlr-/- Mice. Angiology.

Ayalasomayajula, Surya, Meyers, Charles, Koo, Phil, Salunke, Atish Azad, Majumdar, Tapan, Rebello, Sam, Sunkara, Gangadhar and Chen, Jin (2015) Assessment of Pharmacokinetic Drug-Drug Interaction between Pradigastat and Acetaminophen in Healthy Subjects. European Jouranl of Clinical Pharmacology.

Ayalasomayajula, Surya, Meyers, Charles, Yu, Jing, Kagan, Mark, Matott, Ralph, Pal, Parasar, Majumdar, Tapan, Crissey, Anne, Rebello, Sam, Sunkara, Gangadhar and Chen, Jin (2015) Evaluation of food effect on the oral bioavailability of pradigastat, a diacylglycerol acyltransferase 1 inhibitor. Biopharmaceutics & Drug Disposition .

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Bagdanoff, Jeffrey, Jain, Rama, Han, Wooseok, Ding, Yu, Poon, Daniel, Lee, Patrick and Lindvall, Mika (2015) Highly ligand efficient tetrahydro-pyrazolopyridines as inhibitors of ERK2 kinase. Bioorganic and Medicinal Chemistry Letters.

Bagdanoff, Jeffrey, Jain, Rama, Han, Wooseok, Zhu, Shejin, Madera, Ann Marie, Lee, Patrick and Poon, Daniel (2015) Tetrahydropyrrolo-diazepenones as inhibitors of ERK2 kinase. Bioorganic and Medicinal Chemistry Letters, 25 (18). pp. 3788-3792. ISSN 14643405

Bagdanoff, Jeffrey, Xu, Yongjin, Dollinger, Gavin and Martin, Eric (2015) Effect of Chirality on Common in Vitro Experiments: An Enantiomeric Pair Analysis. Journal of Medicinal Chemistry, 58 (15). pp. 5781-5788. ISSN 1520-4804

Bagdanoff, Jeffrey, Xu, Yongjin, Martin, Eric and Dollinger, Gavin (2015) The Effect of Chirality on Common In Vitro Experiments: An Enantiomeric Pair Analysis. Jounal of Medicinal Chemistry.

Balakrishnan, Karthikeyan, Upadhaya, Ajeet Rijal, Steinmetz, Julia, Abramowski, Dorothee, Faendrich, Marcus, Kumar, Satish, Yamaguchi, Haruyasu, Walter, Jochen, Staufenbiel, Matthias and Thal, Dietmar R (2015) Impact of amyloid beta aggregate maturation on antibody treatment in APP23 mice. Acta Neuropathol Comm., 3 (1). p. 41.

Bandell, Michael, Cahalan, Stuart, Lukacs, Victor, Ranade, Sanjeev, Chien, Shu and Patapoutian, Ardem (2015) Piezo1 links mechanical forces to red blood cell volume. eLife, 4 (MAY). ISSN 2050-084X

Bandell, Michael, Xu, Jie, Mathur, Jayanti, Huynh, Truc, Matzen, Jason, Lao, Jianmin, Tully, David, Petrassi, Hank, Schumacher, Andrew, montal, Mauricio, syeda, Ruhma, Dubin, Adrienne, Coste, Bertrand and Patapoutian, Ardem (2015) Chemical activation of the mechanotransduction channel Piezo1. eLife, 4 (MAY). ISSN 2050084X

Banigan, James R, Gayen, Anindita, Cho, Min-Kyu and Traaseth, Nathaniel J (2015) A structured loop modulates coupling between the substrate-binding and dimerization domains in the multidrug resistance transporter EmrE. Journal of Biological Chemistry, 290 (2). pp. 805-814. ISSN 0021-92581083-351X

Barsanti, Paul, Aversa, Robert, Jin, Jeff, Pan, Yue, Lu, Yipin, Elling, Robert, Jain, Rama, Knapp, Mark, Lin, Xiaodong, Rudewicz, Patrick, Sim, Janet, Taricani, Lorena, Thomas, George, Xiao, Linda and Yue, Qin (2015) Structure based drug design of novel potent and selective tetrahydropyrazolo[1,5-a]pyrazines as ATR inhibitors. ACS Medicinal Chemistry Letters, 6 (1). pp. 37-41. ISSN 1948-58751948-5875

Barsanti, Paul A., Pan, Yue, Lu, Yipin, Jain, Rama, Cox, Matthew, Aversa, Robert, Dillon, Michael, Elling, Robert, Hu, Cheng, Jin, Jeff, Knapp, Mark, Lan, Jiong, Ramurthy, Savithri, Rudewicz, Patrick, Setti, Lina, Subramanian, Sharadha, Mathus, Michelle, Taricani, Lorena, Thomas, George, Xiao, Linda and Yue, Qin (2015) Structure-based Drug Design of Novel, Potent and Selective Azabenzimidazoles (ABI) as ATR Inhibitors. ACS Medicinal Chemistry Letters, 6 (1). pp. 42-46. ISSN 1948-58751948-5875

Bednarczyk, Dallas and Boiselle, Carri (2015) Transport of coproporphyrins I and III by organic anion transporting polypeptides (OATP) 1B1 and 1B3. Xenobiotica, 46 (5). pp. 457-466. ISSN 1366-5928

Behnke, Dirk, Cotesta, Simona, Hintermann, Samuel, Fendt, Markus, Gee, Christine, Jacobson, Laura, Laue, Grit, Meyer, Arndt, Wagner, Beatrix, Badiger, Sangamesh, Chaudhari, Vinod, Chebrolu, Murali, Pandit, Chetan, Hoyer, Daniel and Betschart, Claudia (2015) Discovery of 1H-pyrazolo[3,4-b]pyridines as potent dual orexin receptor antagonists (DORAs). Bioorganic and Medicinal Chemistry Letters, 25 (23). pp. 5555-5560. ISSN 0960-894X

Benjamin, Amanda, Gallacher, David J, Gintant, Gary, Greiter-Wilke, Andrea, Guillon, Jean-Michel, Kasia, Cheiko, Leishman, Derek, Levesque, Paul, Louttit, James, Prelle, Katja, Ratcliffe, Sian, Sannajust, Frederick, Ledieu, David, Vargas, Hugo and Valentin, Jean-Pierre (2015) Renal studies in safety pharmacology and toxicology: A survey conducted in the top 15 pharmaceutical companies. Journal of Pharmacological and Toxicological Methods.

Bhansali, Suraj, Mullane, Kathleen, Ting, Lillian, Leeds, Jennifer, Dabovic, Kristina, Praestgaard, Jens and Pertel, Peter (2015) Pharmacokinetics of LFF571 and vancomycin in patients with moderate Clostridium difficile infections. Antimicrobial Agents and Chemotherapy, 59 (3). pp. 1441-1445. ISSN 1098-6596

Bhattacharjee, Maumita , Coburn, Jeannine , Centola, Matteo, Murab, Sumit , Barbero, Andrea , Kaplan, David L., Martin, Ivan and Ghosh, Sourabh (2015) Tissue engineering strategies to study cartilage development, degeneration and regeneration. Advanced Drug Delivery Reviews, 84. pp. 107-122. ISSN 0169409X

Biswal, Shibadas, Polus, Florine, Pal, Parasar, Veldandi, Uday Kiran and Legangneux, Eric (2015) Pharmacokinetic and pharmacodynamic interaction of siponimod (BAF312) and propranolol in healthy subjects. International Journal of Clinical Pharmacology and Therapeutics, 53 (10). pp. 855-865. ISSN 0946-1965

Biswal, Shibadas, Polus, Florine, Pal, Parasar, Veldandi, Uday Kiran and Legangneux, Eric (2015) Pharmacokinetic and pharmacodynamic interaction of siponimod (BAF312) and propranolol in healthy subjects. International Journal of Clinical Pharmacology and Therapeutics, 53 (10). pp. 855-865. ISSN 0946-1965

Bizet, Albane, Becker-Heck, Anita, Ryan, Rebecca, Weber, Kristina, Filhol, Emilie, Krug, Pauline, Halbritter, Jan, Linghu, Bolan, Oakeley, Edward James, Bole-Feysot, Christine, Nitschke, Patrick, Serluca-Aegerter, Fabrizio, Schmidt, Swetlana, Lasbennes-Eckerlen, Marie-Christine, Damask, Amy, Yang, Fan, Bouwmeester, Antonius, Valette, Huguette, Pinson, Lucile, Cassuto, Elisabeth, Dubot, Philippe, Soliman, Neveen, Sahel, Jose, Salomon, Remi, Antignac, Corinne, Gubler, Marie-Claire, Chibout, Salah-Dine, Szustakowski, Joseph, Hildebrandt, Friedhelm, Lorentzen, Esben, Sailer, Andreas, Benmerah, Alexandre, Saint-Mezard, Pierre and Saunier, Sophie (2015) Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization. Nat Comm. pp. 1-14. ISSN 2041-1723 (Electronic); 2041-1723 (Linking)

Blakeley, Daniel, Sykes, David, Aston, Philip and Charlton, Steven (2015) Simulating the influence of plasma protein on measured receptor affinity in biochemical assays reveals the utility of Schild analysis for estimating compound affinity for plasma proteins. British Journal of Pharmacology, 172 (21). pp. 5037-5049. ISSN 1476-5381

Blanz, Joachim, Delemonte, Thierry, Pearson, David, Luneau, Alexandre, Ritzau, Michael, Gertsch, Werner, Ramstein, Philippe, Dayer, Jerome, Desrayaud, Sandrine, Braun, Elisabeth and Aichholz, Reiner (2015) Micropreparative isolation and NMR structure elucidation of metabolites of a drug candidate from rat bile and urine. Journal of Chromatography B: Biomedical Sciences and Applications, 989. pp. 1-10.

Blatter, Markus, Dunin-Horkawicz, Stanislaw, Grishina, Inna , Maris, Christophe , Thore, Stephane , Maier, Timm , Bindereif, Albrecht and Allain, Frédéric H.-T. (2015) The Signature of the Five-Stranded vRRM Fold Defined by Functional, Structural and Computational Analysis of the hnRNP L Protein. Journal of Molecular Biology.

Bojkovic, Jade, Richie, Daryl, Six, David, Rath, Christopher, Sawyer, William and Dean, Charles (2015) Characterization of an Acinetobacter baumannii lptD Deletion Strain; Permeability Defects and Response to Inhibition of Lipopolysaccharide and Fatty Acid Biosynthesis. Journal of Bacteriology, 198 (4). pp. 731-741. ISSN 1098-5530

Bojkovic, Jade, Richie, Daryl, Six, David, Rath, Christopher, Sawyer, William, Hu, Daniel and Dean, Charles (2015) Characterization of an A. baumannii lptD Deletion Strain; Permeability Defects and Response to Inhibition of Lipopolysaccharide and Fatty Acid Biosynthesis. Journal of Bacteriology, 198 (4). pp. 731-741.

Bold, Guido, Schnell, Christian, Mcsheehy, Paul M.J., Brueggen, Josef, Mestan, Juergen, Manley, Paul W., Drueckes, Peter, Burglin, Marion, Duerler, Ursula, Loretan, Jacqueline, Reuter, Robert, Wartmann, Markus, Theuer, Andreas, Bauer-Probst, Beatrice, Martiny-Baron, Georg, Allegrini, Peter Roland, Furet, Pascal, Wood, Jeanette, Littlewood-Evans, Amanda and Goepfert, Arnaud (2015) A novel potent oral series of VEGFR2 inhibitors abrogate tumor growth by inhibiting angiogenesis. Journal of medicinal chemistry, 59 (1). pp. 132-146. ISSN 0022-26231520-4804

Boone, Jonathan, Cooper, Sara, Johnston, Bobby, Arend, Rebecca, Gilchrest, Austin, Oelschlager, Denise, Grizzle, William, McGwin, Gerald, Gangrade, Abhishek, Straughn, J. Michael and Buchsbaum, Donald (2015) Targeting the Wnt/β-catenin pathway in primary ovarian cancer with the porcupine inhibitor WNT974. Laboratory Investigation.

Bornancin, Frederic, Renner, Florian, Touil, Ratiba, Kolb, Yeter, Touil, Ismahane, Rush, James, Smith, Paul, Bigaud, Marc, Zamurovic Ribrioux, Natasa, Junker Walker, Ursula, Burkhart, Christoph, Dawson King, Janet, Regnier, Catherine, Niwa, Satoru, Katopodis, Andreas, Nuesslein-Hildesheim, Barbara, Weckbecker, Gisbert, Zenke, Gerhard, Kinzel, Bernd, Traggiai, Elisabetta, Brenner, Dirk, Brüstle, Anne, St Paul, Michael, McCoy, Kathy D., Rolink, Antonius, Mak, Tak W, Ohashi, Pamela S, Patel, Dhavalkumar and Calzascia, Thomas (2015) Deficiency in MALT1 paracaspase activity promotes multi-organ inflammation. Journal of Immunology, 194 (8). pp. 3723-3734. ISSN 1550-6606

Bouslimani, Amina , Porto, Carla , Rath, Christopher, Wang, Mingxun , Yurong , Guo , Gonzalez, Antonio , Berg-Lyon, Donna , Ackermann, Gail , Christensen , Gitte Julie Moeller , Teruaki , Nakatsuji , Zhang , Lingjuan , Borkowski , Andrew , Meehan , Michael , Dorrestein , Kathleen , Gallo , Richard , Bandeira, Nuno , Knight , Rob , Alexandrov , Theodore and Dorrestein , Pieter (2015) 3D molecular cartography of the human skin surface. PNAS.

Bradley, Michelle, Brown, Zarin, Charlton, Steven, Cromie, Karen, Dombrecht, Bruno, De Taeye, Severine, Van den Heede, Kim, Van Heeke, Gino, Kent, Toby, Laeremans, Toon, Manini, Jodie, Roobrouck, Annelies, Steffensen, Soren, Vlerick, David and Willis, Jennifer (2015) Potent and efficacious inhibition of CXCR2 signaling by biparatopic nanobodies combining two distinct modes of action. Molecular Pharmacology, 87 (2). pp. 251-262. ISSN 1521-0111

Briard, Emmanuelle, Rudolph, Bettina, Desrayaud, Sandrine, Krauser, Joel and Auberson, Yves (2015) MS565, a SPECT tracer for evaluating the brain penetration of BAF312 (siponimod). ChemMedChem, 10 (6). pp. 1008-1018. ISSN 18607179

Bringer, Pauline, Jensen, Michael Rugaard and Gembarska, Agnieszka (2015) Identification of piggyBac transposon insertions in malignant tumors. Master degree Bio-engineering applied to health, University of Toulouse III.

Brogdon, Jennifer, Loew, Andreas, Thekkat, Pramod, Idamakanti, Neeraja, Engels, Boris, Singh, Reshma, Ezell, Tucker, Zhou, Li, Ramones, Melissa, Li, Na, Maus, Marcela, Johnson, Laura, Scholler, John, June, Carl, Okada, Hideho, Plesa, Gabriela, Patel, Prachi, McGettigan, Shannon, Nace, Arben, Ohkuri, Takayuki, Kosaka, Akemi, Chen, Taylor, Fraietta, Joseph, Kloss, Christopher, Boesteanu, Alina, Cogdill, Alexandria and Seykora, John (2015) Validation of a humanized anti-EGFR variant III chimeric antigen receptor for a Phase I trial of CART-EGFRvIII in glioblastoma. Science Translational Medicine.

Burger, Matthew, Nishiguchi, Gisele, Han, Wooseok, Lan, Jiong, Simmons, Bob, Atallah, Gordana, Ding, Yu, Tamez Jr., Victoriano, zhang, yanchen, mathur, michelle, muller, kristine, Bellamacina, Cornelia, Lindvall, Mika, Zang, Richard, Huh, Kay, Feucht, Paul, Zavorotinskaya, Tatiana, Dai, Yumin, Basham, Steve, Chan, Julie, Ginn, Elaine, Aycinena, Alex, Holash, Jocelyn, Castillo, Joseph, Langowski, John, Wang, Yingyun, Chen, Min, Lambert, Amy, Fritsch, Christine, Kauffmann, Audrey, Pfister-Wagner, Estelle, Vanasse, K. Gary and Garcia, Pablo (2015) Identification of N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (PIM447), a Potent and Selective Proviral Insertion Site of Moloney Murine Leukemia (PIM) 1,2 and 3 Kinase Inhibitor in Clinical Trials for Hematological Malignancies. Journal of Medicinal Chemistry.

Busby, Scott (2015) MALDI High-Throughput Screening beyond 100,000 Samples per Day in Drug Discovery. Bruker Poster Note PN-05.

Busche, Marc Aurel, Adelsberger, Helmuth, Kekus, Maja, Förstl, Hans, Nelken, Israel and Konnerth, Arthur (2015) Breakdown of slow-wave oscilliations in mouse modles of Alzheimer's disease. Nature Neuroscience.

Busche, Marc Aurel, Grienberger, Christine, Keskin, Aylin Derya, Song, Beomjong, Neumann, Ulf, Staufenbiel, Matthias, Förstl, Hans and Konnerth, Arthur (2015) Decreased amyloid-β but increased neuronal hyperactivity by immunotherapy in Alzheimer´s models. Nature Neuroscience.

Bushee, Jennifer, Dunne, Christine and Argikar, Upendra (2015) An in vitro approach to investigate ocular metabolism: Part II - Betaxolol. Xenobiotica.

Butler, Rebecca, Smith, Nichola and Hunt, Thomas (2015) ENaC Inhibitors for the Treatment of Cystic Fibrosis. Pharmaceutical Patent Analysis.

C

Camargo, Miguel, Zhang, X D, Loerch, Patrick, Caceres, RM, Marine, SD, UVa, P, Ferrer, M, Majercak, J, Ray, WJ, Yi-An, C, Shearman, MS and Mizuguchi, Kenji (2015) PATHWAY-BASED ANALYSIS OF GENOME-WIDE SIRNA SCREENS REVEALS THE REGULATORY LANDSCAPE OF APP PROCESSING. PLOS ONE, 10 (2). ISSN 1932-6203

Camenisch, Gian P., Poller, Birk, Kunze, Annett and Huwyler, Jörg (2015) Application of the extended clearance concept classification system (ECCCS) to predict the victim drug-drug interaction potential of statins. Drug Metabolism and Personalized Therapy, 30 (3). pp. 175-188. ISSN 23638915

Camenisch, Gian P., Riede, Julia, Kunze, Annett, Huwyler, Jörg, Poller, Birk and Umehara, Ken-Ichi (2015) The extended clearance model and its use for the interpretation of hepatobiliary elimination data. ADMET&DMPK.

Canapari, CA, Barrowman, N, Hoey, L, Walker, SW, Townsend, E, Tseng, BS and Katz, SL (2015) Truncal Fat Distribution Correlates With Decreased Vital Capacity in Duchenne Muscular Dystrophy. Pediatric Pulmonology. pp. 63-70.

Carballido, Jose, Regairaz Kalenga Kapiamba, Camille, Raad, Layla and Rauld, Celine (2015) IL17A/CCR6 expression in human T cells. Lab meeting at D-BSSE, Basel.

Carson, Cheryl, Raman, Pichai, Tullai, Jennifer, Xu, Lei, Henault, Martin, Thomas, Emily, Yeola, Sarita, Lao, Jianmin, McPate, Mark, Verkuyl, J Martin, Marsh, George, Sarber, Jason, Amaral, Adam, Bailey, Scott, Lubicka, Danuta, Pham, Helen, Miranda, Nicolette, Ding, Jian, Tang, Hai-Ming, Ju, Haisong, Tranter, Pamela, Ji, Nan, Krastel, Philipp, Jain, Rishi K, Schumacher, Andrew M, Loureiro, Joseph J, George, Elizabeth, Berellini, Giuliano, Ross, Nathan T, Bushell, Simon M, Erdemli, Gül and Solomon, Jonathan M (2015) Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation. PloS one, 10 (6). e0127498. ISSN 1932-6203

Castanotto, Daniela, Lin, Min, Kowolik, Claudia, Wang, LiAnn, Ren, Xiao-Qin, Soifer, Harris, Koch, Troels, Hansen, Bo Rode, Armstrong, Brian, Wang, Zhigang, Bauer, Paul, Rossi, John and Stein, CA (2015) A cytoplasmic pathway for gapmer antisense oligonucleotide-mediated gene silencing in mammalian cells. Science Advances, 43 (19). pp. 9350-9361. ISSN 1362-4962

Chalmin, Fanny, Rochemont, Viviane, Lippens, Carla, Clottu, A, Sailer, Andreas, Merkler, Doron, Hugues, Stephanie and Pot, Caroline (2015) Oxysterols regulate CD4+ T cell trafficking during experimental autoimmune encephalomyelitis. Journal of Autoimmunity, 56. pp. 45-55.

Chandramouli, Sumana, Ciferri, Claudio, Gerrein, Rachel, Nikitin, Pavel, Calo', Stefano, Balabanis, Kara, Settembre, Ethan, Monroe, James, Hebner, Christy and Carfi, Andrea (2015) Structure of HCMV glycoprotein B in the postfusion conformation bound to a neutralizing human antibody. Nature Communications, 6. ISSN 2041-1723

Chappuis, Quentin, Bornet, Aurelien, Milani, Jonas, Vichoud, Basile, Gossert, Alvar, Bodenhausen, Geoffrey and Jannin, Sami (2015) The Preparation of Hyperpolarized Water and its Use to Enhance "waterLOGSY" Drug Screening. J Phys Chem Lett, 6 (9). pp. 1674-1678. ISSN 1948-7185

Chatterji, Udayan, Garcia-Rivera, Jose A., Baugh, James, Gawlik, Katarzyna, Wong, Kelly, Zhong, Weidong, Brass, Cliff, Naoumov, Nikolai and Gallay, Philippe A. (2015) The combination of alisporivir plus an NS5A inhibitor provides additive to synergistic anti-hepatitis C virus activity without detectable cross-resistance,. Antimicrobial Agents and Chemotherapy.

Chen, Jin, Bhansali, Suraj, Neelakantham, Srikanth Raju, Trusley, Craig, Majumdar, Tapan, Rebello, Sam, Sunkara, Gangadhar and Meyers, Charles (2015) Effect of Pradigastat, a Diacylglycerol Acyltransferase 1 Inhibitor, on the Pharmacokinetics of a Combination Oral Contraceptive in Healthy Female Subjects. International journal of clinical pharmacology and therapeutics, 53 (4). pp. 317-324. ISSN 0946-1965

Chen, Jin, Bhansali, Suraj, Neelakantham, Srikanth Raju, Trusley, Craig, Majumdar, Tapan, Rebello, Sam, Sunkara, Gangadhar and Meyers, Charles (2015) Effect of pradigastat, a diacylglycerol acyltransferase 1 inhibitor, on the pharmacokinetics of a combination oral contraceptive in healthy female subjects. International Journal of Clinical Pharmacology and Therapeutics, 53 (4). pp. 317-324. ISSN 0946-1965

Chen, Qiuyan, Vishnivetskiy, Sergey A., Zhuang, Tiandi, Cho, Min-Kyu, Thaker, Tarjani M., Sanders, Charles R., Gurevich, Vsevolod V. and Iverson, T. M. (2015) The Rhodopsin-Arrestin-1 Interaction in Bicelles. Methods in molecular biology, 1271. pp. 77-95. ISSN 1940-6029; 1064-3745

Chen, Yen Liang, Shi, Pei-Yong and Yokokawa, Fumiaki (2015) Nucleoside inhibitors of dengue virus. Antiviral Research, 122. pp. 12-19. ISSN 01663542

Chitnis, Shripad, Kulmatycki, Kenneth, Han, Yi, Sunkara, Gangadhar, Yamaguchi, Masayuki, Nozaki, Sachiko and Zhao, Rong (2015) Population pharmacokinetic modeling and noncompartmental analysis demonstrated bioequivalence between metformin component of metformin/vildagliptin fixed-dose combination products and metformin immediate-release tablet sourced from various countries. Clinical Pharmacology in Drug Developement, 5 (1). pp. 40-51.

Choi, Vivian, Bigelow, Chad, Mcgee, Terri, Gujar, Akshata, Li, Hui, Hanks, Shawn, Vrouvlianis, Joanna, Maker, Michael, Leehy, Barrett, Zhang, Yiqin, Aranda, Jorge, Bounoutas, George, Demirs, John, Yang, Junzheng, Richard, Ornberg, Wang, Yu, Martin, Wendy, Stout, Kelly, Argentieri, Gregory, Grosenstein, Paul, Diaz, Danielle, Turner, Oliver, Jaffee, Bruce, Police, Seshidhar and Dryja, Ted (2015) AAV-mediated RLBP1 gene therapy improves the rate of dark adaption in Rlbp1 knockout mice. AAV-mediated RLBP1 gene therapy improves the rate of dark adaption in Rlbp1 knockout mice.

Christ, Andreas Dominik and Soldermann, Nicolas (2015) An open-label, non-randomized, within-patient dose-finding study followed by a randomized, double-blind placebo controlled study with extension to assess the safety and efficacy of CDZ173 in patients with APDS/PASLI (Activated phosphoinositide 3-kinase delta syndrome/ p110δ-activating mutation causing senescent T cells, lymphadenopathy and immunodeficiency). Part of a CRADA with NIH, thus NIH will be allowed to make the abstract publicly available.

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Jahnke, Wolfgang, Bold, Guido, Marzinzik, Andreas, Ofner, Silvio, Pelle, Xavier, Cotesta, Simona, Bourgier, Emmanuelle, Lehmann, Sylvie, Henry, Christelle, Hemmig, Rene, Green, Jonathan and Rondeau, Jean-Michel (2015) A General Strategy for Targeting Drugs to Bone. Angewandte Chemie Int Edition, 54 (48). pp. 14575-14579. ISSN 14337851

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James, Alexander David, Blumenstein, Lars, Glaenzel, Ulrike, Jin, Yi, Demailly, Arnold, Jakab, Annamaria, Hansen, Regine, Hazell, Katharine Mary, Mehta, Anuradha, Trandafir, Lucia, Coughlin, Christina and Swart, Pieter Jacob (2015) Absorption, distribution, metabolism, and excretion of [14C]BYL719 (alpelisib) in healthy male volunteers. Cancer Chemotherapy and Pharmacology, 76. pp. 751-760.

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Jiang, Xiaomo, Kheifets, Olga, Zamponi, Raffaella, Yang, Yi and Cong, Feng (2015) Dishevelled promotes wnt receptor degradation through recruitment of znrf3/rnf43 e3ubiquitin ligases. Molecular Cell, 58 (3). pp. 522-533. ISSN 1097-4164

Jing, Weiqing, Gershan, Jill A, Weber, James, Tlomak, Dominique, McOlash, Laura, Sabatos-Peyton, Catherine and Johnson, Bryon D (2015) Combined immune checkpoint protein blockade and low dose whole body irradiation as immunotherapy for myeloma. Journal for ImmunoTherapy of Cancer, 3 (1). ISSN 2051-1426

Jones, Christopher (2015) The N-terminal Helical Region of the Hepatitis C Virus p7 Protein is Critical for Infectious Virus Production. PLoS Pathogens, 11 (11). e1005297. ISSN 1553-7374

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Karpov, Alexei and Grotzfeld, Robert (2015) OAK-approved research summary for the postdoc website. OAK-approved research summary for the postdoc website .

Kasteleijn-Nolst Trenité, D, Brandt, C, Mayer, T, Rosenow, F, Schmidt, B, Steinhoff, BJ, Gardin, Anne, Imbert, Georges, Johns, Donald, Sagkriotis, Alexandros and Kucher, Klaus (2015) Dose-dependent suppression of human photoparoxysmal response with the competitive AMPA/kainate receptor antagonist BGG492. Epilepsia, 56 (6). pp. 924-932. ISSN 1528-1167

Kaufmann, Markus, Schuffenhauer, Ansgar, Fruh, Isabelle, Klein, Jessica, Thiemeyer, Anke, Rigo, Pierre, Gomez-Mancilla, Baltazar, Heidinger-Millot, Valerie, Bouwmeester, Antonius, Schopfer, Ulrich, Mueller, Matthias, Fodor, Barna and Cobos-Correa, Amanda (2015) High Throughput Screening using iPSC-derived neuronal progenitors to identify compounds counteracting epigenetic gene silencing in Fragile X Syndrome. Journal of Biomolecular Screening, 20 (9). pp. 1101-1111. ISSN 1087-05711552-454X

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Kelley, Brian, Brown, Scott P, Warren, Gregory L and Muchmore, Steven W (2015) POSIT: Flexible Shape-Guided Docking For Pose Prediction. Journal of Chemical Information and Modeling.

Kim, Munkyung, Piaia, Alessandro, Shenoy, Neeta, Kagan, David, Gapp, Berangere, Kueng, Benjamin, Weber, Delphine, Dietrich, Bill and Ksiazek, Iwona (2015) Progression of Alport Kidney Disease in Col4a3 knock out mice is independent of sex or macrophage depletion by clodronate treatment. PLoS ONE, 10 (11). ISSN 1932-6203

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Kizuka, Yasushiko, Kitazume, Shinobu, Fujinawa, Reiko, Saito, Takashi, Iwata, Nobuhisa, Saido, Takaomi C, Nakano, Miyako, Yamaguchi, Yoshiki, Hashimoto, Yasuhiro, Staufenbiel, Matthias, Hatsuda, Hisoshi, Endo, Tamao and Taniguchi, Naoyuki (2015) Loss of bisected glycan decreases Abeta generation by relocating BACE1 to the lysosomal degradation pathway. Biochemical Journal, 473 (1). pp. 21-30. ISSN 0264-60211470-8728

Klein, Theo, Fung, Shane-Yu, Renner, Florian, Blank, Michael, Dufour, Antoine, Kang , Sohyeong, Bolger-Munro, Madison, Scurll, Joshua, Priatel, John, Schweigler, Patrick, Melkko, Samu, Gold, Michael, Viner, Rosa, Regnier, Catherine, Turvey, Stuart and Overall, Christopher (2015) The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-κB signalling. Nature Communications, 6. p. 8777. ISSN 2041-1723

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Klocks, Cathelijne, Berger, Claudia, Cortez, Pierre, Yann, Dean, Heinrich, Julia, Jensen Bjerring, Lisbeth, Koppenburg, Vera, Kostense, Stefan, Kramer, Daniel, Spindeldreher, Sebastian and Kirby, Hishani (2015) A fit-for-purpose strategy for the risk-based immunogenicity testing of biotherapeutics - a European industry perspective. Journal of Immunological Methods.

Klumpp, Martin (2015) Non-Stoichiometric Inhibition in Integrated Lead Finding – A Literature Review. Expert Opinion on Drug Discovery, 11 (2). pp. 149-162. ISSN 1746-04411746-045X

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Kramer, Christian, Ertl, Peter and Liedl, Klaus R (2015) UNIQUE MACROCYCLES IN THE TAIWAN TCM DATABASE. Planta Medica.

Krumova, Petranka, Reyniers, Lauran, Meyer, Marc, Stauffer, Daniela, Gerrits, Bertran, Hoving, Sjouke, Kaupmann, Klemens, Voshol, Johannes, Fabbrio, Dario, Bauer, Andreas, Rovelli, Giorgio, Taymans, Jean-Marc, Bouwmeester, Antonius and Baekelandt, Veerle (2015) Chemical genetic approach identifies microtubule affinity-regulating kinase 1 as a leucine-rich repeat kinase 2 substrate. FASEB Journal, 29 (7). pp. 2980-2992. ISSN 1530-6860

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Lazic, Stanley (2015) Analytical strategies for the marble burying test: avoiding impossible predictions and invalid p-values. BMC Research Notes.

Lee, Hyunwoo, Haller, Corinne, Doll, Thierry, Fruh, Isabelle, Gubser Keller, Caroline, Richards, Shola, Ibig-Rehm, Yvonne, Patoor, Maude, Goette, Marjo, Bouchez, Laure and Mueller, Matthias (2015) Identification of Small Molecules Which Induce Skeletal Muscle Differentiation in Embryonic Stem Cells via Activation of the Wnt and Inhibition of Smad2/3 and Sonic Hedgehog Pathways. Stem Cells, 34 (2). pp. 299-310. ISSN 10665099

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Li, Li, Vashisht, Kapil, Boisclair, Julie, Li, Wenkui, Lin, Tsu-Han, Schmid, Herbert, Kluwe, William, Schoenfeld, Heidi and Hoffmann, Peter (2015) LCI699, a potent 11β-hydroxylase inhibitor, administered in combination with the multireceptor-targeted somatostatin analog pasireotide: A 13-week study in rats. Toxicology and Applied Pharmacology, 286 (3). pp. 224-233. ISSN 0041008X

Li, Nanxin, Molteni, Valentina, Liu, Bo, Tuntland, Tove, Loren, Jon, Gordon, William, Brodeur, Garrett, Iyer, Radhika and Croucher, Jamie (2015) TrkB inhibition by GNF-4256 slows growth and enhances chemotherapeutic efficacy in neuroblastoma xenografts. Cancer Chemotherapy and Pharmacology, 75 (1). pp. 131-141. ISSN 1432-0843

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Litovchick, Alexander, Dumelin, Christoph, Habeshian, Sevan, Gikunju, Diana, Guié, Marie-Aude, Centrella, Paolo, Zhang, Ying, Sigel, Eric, Cuozzo, John, Keefe, Anthony and Clark, Matthew (2015) Encoded Library Synthesis Using Chemical Ligation and the Discovery of sEH Inhibitors from a 334-Million Member Library. Scientific Reports , 5. ISSN 2045-2322

Liu, L, Tang, M, Walsh, MJ, Brimacombe, KR, Pragani, R, Tanega, C, Rohde, JM, Baker, HL, Fernandez, E, Blackman, B, Bougie, JM, Leister, WH, Auld, DS, Shen, M, Lai, K and Boxer, MB (2015) Structure activity relationships of human galactokinase inhibitors. Bioorganic and Medicinal Chemistry Letters. pp. 721-727.

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London, Anne, Japutra, Chietara, Planck, Kyle, Lihon, Michael and Nguyen, Andrew (2015) A novel method to determine residual detergent in biological samples post endotoxin reduction treatment and evaluation of strategies for subsequent detergent removal. International Immunopharmacology.

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Lukacs, Viktor, Mathur, Jayanti, Bayrak-Toydemir, Pinar, Rong, Mao, Longo, Nicola, Day, Ronald, Procter, Melinda, Cahalan, Stuart, Kim, Helen J, Bandell, Michael, Stevenson, David A, Patapoutian, Ardem and Krock, Bryan L (2015) Impaired PIEZO1 function in patients with a novel autosomal recessive congenital lymphatic dysplasia. Nature communications, 6. p. 8329. ISSN 2041-1723

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