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Number of items: 408.

Ménard, Joël and Watson, Catherine and Rigel, Dean and Jeng, Arco Y. and Liang, Guiqing and Rebello, Sam and Zhang, Yiming and Dole, William and Fu, Fumin and Beil, Michael and Liu, Jing and Chen, Wei and Hu, Chii-Whei and Leung-Chu, Jennifer and LaSala, Daniel (2015) Aldosterone synthase inhibition: cardiorenal protection in animal disease models and translation of hormonal effects to human subjects. Journal of Translational Medicine.

A

Altmann, Eva and Grosche, Philipp and Sirockin, Finton and Mac Sweeney, Aengus and Ramage, Paul and Erbel, Paulus and Melkko, Samu and Bernardi, Anna and Hughes, Nicola and Ellis, David and Jarrousse Coscoy, Nadine (2015) Structure-based design and optimization of potent inhibitors of the adenoviral protease. Structure-based design and optimization of potent inhibitors of the adenoviral protease, 25 (3). pp. 438-443. ISSN 0960-894X

Alzahrani, Mohammad M. and Makhdom , Asim M. and Rauch, Frank and Lauzier, Dominique and Kotsiopriftis, Maria and Hamdy, Reggie C. (2015) Assessment of the Effect of Systemic Delivery of Sclerostin Antibodies on WNT Signaling in Distraction Osteogenesis Using Immunohistochemistry. Journal of orthopaedic research.

Ammann, P and Zacchetti, G and Gasser, Juerg Andreas and Lavet, C and Rizzoli, R (2015) Protein malnutrition attenuates bone anabolic response to PTH in female rats. Endocrinology.

Annan, Kofi and Ekuadzi, Edmund and Asare, Cindy and Sarpong, Kwane and Pistorius, Dominik and Oberer, Lukas and Gyan, Ben A. and Ofori, Michael (2015) Antiplasmodial Constituents from the Stem Bark of Polyalthia longifolia var Pendula. Phytochemistry Letters, 11. pp. 28-31.

April, Myriam and Daniels, Thomas and Forster, Cornelia and Jain, Monish and Kanter, Aaron and Li, Jingzhou and Streeper, Ryan and Wang, Bing and Brewer, Jason and Gilmore, Thomas and Kwak, Youngshin and Serrano-Wu, Michael and Szklennik, Paul and Thompson, James and McQuire , Les (2015) Discovery of diamide compounds as diacylglycerol acyltransferase 1 (DGAT1) inhibitors. Bioorganic and medicinal chemistry letters, 26 (4). pp. 1245-1248. ISSN 0960894X

Arduin, Elodie and Arora, Seguinde and Bamert, Paulo Roky and Kuiper, Torsten and Popp, Simone and Geisse, Sabine and Grau, Roger and Calzascia, Thomas and Zenke, Gerhard and Kovarik, Jiri (2015) Highly reduced binding to high and low affinity mouse Fc gamma receptors by L234A/L235A and N297A Fc mutations engineered into mouse IgG2a. Molecular Immunology, 63 (2). pp. 456-463.

Arias, HR and Feuerbach, Dominik and Ortells, Marcelo (2015) Functional and Structural Interaction of (-)-Lobeline with human α4β2 and α4β4 Nicotinic Acetylcholine Receptor Subtypes. Int. J. Biochem. Cell Bio.

Arias, HR and Targowska-Duda, KM and Feuerbach, Dominik and Jozwiak, K (2015) The antidepressant-like activity of nicotine, but not 3-furan-2-yl-N-p-tolyl-acrylamide, is regulated by the nicotinic receptor β4 subunit. Neuroscience letter.

Arias, Hugo R and Targowska-Duda, Katarzyna M and Feuerbach, Dominik and Jozwiak, Krzysztof (2015) Coronaridine congeners inhibit human α3β4 Nicotinic Acetylcholine Receptors by interacting with luminal and non-luminal sites. Biochemistry.

Arista, Luca and Renier , van der Westhuyzena and Susan, Winks and Colin, Wilson and Grant, Boyle and Richard, Gessner and Candice, Soares de Melo and Dale, Taylor and Carmen, de Kock and Mathew, Njoroge and Christel, Brunschwig and Nina, Lawrence and Frik, Sirgel and Paul, van Helden and Ronnett, Seldon and Atica, Moose and Digby, Warner and Ujjini , Manjunatha and Paul, Smith and Leslie, Street and Kelly, Chibale (2015) Pyrrolo[3,4-c]pyridine-1,3(2H)-diones: A new anti-mycobacterial class that targets mycobacterial energy metabolism. Pyrrolo[3,4-c]pyridine-1,3(2H)-diones: A new anti-mycobacterial class that targets mycobacterial energy metabolism, 58 (23). pp. 9371-9381. ISSN 0022-26231520-4804

Ashok, Y and Nanekar, R and Jaakola, V-P (2015) Defining thermostability of membrane proteins by western blotting. Protein engineering, design & selection : PEDS, 28 (12). pp. 539-542. ISSN 1741-0134

Asmus, Lutz R. and Grimshaw, John and Richle, Philipp and Eicher, Barbara and Urech, David M. and Gurny, Robert and Moeller, Michael (2015) Injectable Formulations for an Intravitreal Sustained-Release Application of a Novel Single-Chain VEGF Antibody Fragment. European Journal of Pharmaceutics and Biopharmaceutics, 95 (Part B). pp. 250-260. ISSN 0939-6411

Auld, Douglas and Jimenez, Marta (2015) Examining Ligand-based Stabilization of Proteins in Cells with MEK1 Kinase Inhibitors. Assay and Drug Development Technologies, 13 (5). pp. 266-276. ISSN 1540-658X1557-8127

Auld, Douglas and Wassermann, Anne and Camargo, Miguel (2015) Composition and applications of focus libraries to phenotypic assays. Frontiers in Pharmacology, 5. ISSN 1663-9812

Awan, Zuhier and Denis, Maxime and Awan, Amani and Gram, Hermann and Seidah, Nabil and Genest, Jaques (2015) Inhibition of Interleukin-1β by a Monoclonal Antibody Therapy Reduces Vascular Calcification in Ldlr-/- Mice. Angiology.

Ayalasomayajula, Surya and Meyers, Charles and Koo, Phil and Salunke, Atish Azad and Majumdar, Tapan and Rebello, Sam and Sunkara, Gangadhar and Chen, Jin (2015) Assessment of Pharmacokinetic Drug-Drug Interaction between Pradigastat and Acetaminophen in Healthy Subjects. European Jouranl of Clinical Pharmacology.

Ayalasomayajula, Surya and Meyers, Charles and Yu, Jing and Kagan, Mark and Matott, Ralph and Pal, Parasar and Majumdar, Tapan and Crissey, Anne and Rebello, Sam and Sunkara, Gangadhar and Chen, Jin (2015) Evaluation of food effect on the oral bioavailability of pradigastat, a diacylglycerol acyltransferase 1 inhibitor. Biopharmaceutics & Drug Disposition .

B

Bagdanoff, Jeffrey and Jain, Rama and Han, Wooseok and Ding, Yu and Poon, Daniel and Lee, Patrick and Lindvall, Mika (2015) Highly ligand efficient tetrahydro-pyrazolopyridines as inhibitors of ERK2 kinase. Bioorganic and Medicinal Chemistry Letters.

Bagdanoff, Jeffrey and Jain, Rama and Han, Wooseok and Zhu, Shejin and Madera, Ann Marie and Lee, Patrick and Poon, Daniel (2015) Tetrahydropyrrolo-diazepenones as inhibitors of ERK2 kinase. Bioorganic and Medicinal Chemistry Letters, 25 (18). pp. 3788-3792. ISSN 14643405

Bagdanoff, Jeffrey and Xu, Yongjin and Dollinger, Gavin and Martin, Eric (2015) Effect of Chirality on Common in Vitro Experiments: An Enantiomeric Pair Analysis. Journal of Medicinal Chemistry, 58 (15). pp. 5781-5788. ISSN 1520-4804

Bagdanoff, Jeffrey and Xu, Yongjin and Martin, Eric and Dollinger, Gavin (2015) The Effect of Chirality on Common In Vitro Experiments: An Enantiomeric Pair Analysis. Jounal of Medicinal Chemistry.

Balakrishnan, Karthikeyan and Upadhaya, Ajeet Rijal and Steinmetz, Julia and Abramowski, Dorothee and Faendrich, Marcus and Kumar, Satish and Yamaguchi, Haruyasu and Walter, Jochen and Staufenbiel, Matthias and Thal, Dietmar R (2015) Impact of amyloid beta aggregate maturation on antibody treatment in APP23 mice. Acta Neuropathol Comm., 3 (1). p. 41.

Bandell, Michael and Cahalan, Stuart and Lukacs, Victor and Ranade, Sanjeev and Chien, Shu and Patapoutian, Ardem (2015) Piezo1 links mechanical forces to red blood cell volume. eLife, 4 (MAY). ISSN 2050-084X

Bandell, Michael and Xu, Jie and Mathur, Jayanti and Huynh, Truc and Matzen, Jason and Lao, Jianmin and Tully, David and Petrassi, Hank and Schumacher, Andrew and montal, Mauricio and syeda, Ruhma and Dubin, Adrienne and Coste, Bertrand and Patapoutian, Ardem (2015) Chemical activation of the mechanotransduction channel Piezo1. eLife, 4 (MAY). ISSN 2050084X

Banigan, James R and Gayen, Anindita and Cho, Min-Kyu and Traaseth, Nathaniel J (2015) A structured loop modulates coupling between the substrate-binding and dimerization domains in the multidrug resistance transporter EmrE. Journal of Biological Chemistry, 290 (2). pp. 805-814. ISSN 0021-92581083-351X

Barsanti, Paul and Aversa, Robert and Jin, Jeff and Pan, Yue and Lu, Yipin and Elling, Robert and Jain, Rama and Knapp, Mark and Lin, Xiaodong and Rudewicz, Patrick and Sim, Janet and Taricani, Lorena and Thomas, George and Xiao, Linda and Yue, Qin (2015) Structure based drug design of novel potent and selective tetrahydropyrazolo[1,5-a]pyrazines as ATR inhibitors. ACS Medicinal Chemistry Letters, 6 (1). pp. 37-41. ISSN 1948-58751948-5875

Barsanti, Paul A. and Pan, Yue and Lu, Yipin and Jain, Rama and Cox, Matthew and Aversa, Robert and Dillon, Michael and Elling, Robert and Hu, Cheng and Jin, Jeff and Knapp, Mark and Lan, Jiong and Ramurthy, Savithri and Rudewicz, Patrick and Setti, Lina and Subramanian, Sharadha and Mathus, Michelle and Taricani, Lorena and Thomas, George and Xiao, Linda and Yue, Qin (2015) Structure-based Drug Design of Novel, Potent and Selective Azabenzimidazoles (ABI) as ATR Inhibitors. ACS Medicinal Chemistry Letters, 6 (1). pp. 42-46. ISSN 1948-58751948-5875

Bednarczyk, Dallas and Boiselle, Carri (2015) Transport of coproporphyrins I and III by organic anion transporting polypeptides (OATP) 1B1 and 1B3. Xenobiotica, 46 (5). pp. 457-466. ISSN 1366-5928

Behnke, Dirk and Cotesta, Simona and Hintermann, Samuel and Fendt, Markus and Gee, Christine and Jacobson, Laura and Laue, Grit and Meyer, Arndt and Wagner, Beatrix and Badiger, Sangamesh and Chaudhari, Vinod and Chebrolu, Murali and Pandit, Chetan and Hoyer, Daniel and Betschart, Claudia (2015) Discovery of 1H-pyrazolo[3,4-b]pyridines as potent dual orexin receptor antagonists (DORAs). Bioorganic and Medicinal Chemistry Letters, 25 (23). pp. 5555-5560. ISSN 0960-894X

Benjamin, Amanda and Gallacher, David J and Gintant, Gary and Greiter-Wilke, Andrea and Guillon, Jean-Michel and Kasia, Cheiko and Leishman, Derek and Levesque, Paul and Louttit, James and Prelle, Katja and Ratcliffe, Sian and Sannajust, Frederick and Ledieu, David and Vargas, Hugo and Valentin, Jean-Pierre (2015) Renal studies in safety pharmacology and toxicology: A survey conducted in the top 15 pharmaceutical companies. Journal of Pharmacological and Toxicological Methods.

Bhansali, Suraj and Mullane, Kathleen and Ting, Lillian and Leeds, Jennifer and Dabovic, Kristina and Praestgaard, Jens and Pertel, Peter (2015) Pharmacokinetics of LFF571 and vancomycin in patients with moderate Clostridium difficile infections. Antimicrobial Agents and Chemotherapy, 59 (3). pp. 1441-1445. ISSN 1098-6596

Bhattacharjee, Maumita and Coburn, Jeannine and Centola, Matteo and Murab, Sumit and Barbero, Andrea and Kaplan, David L. and Martin, Ivan and Ghosh, Sourabh (2015) Tissue engineering strategies to study cartilage development, degeneration and regeneration. Advanced Drug Delivery Reviews, 84. pp. 107-122. ISSN 0169409X

Biswal, Shibadas and Polus, Florine and Pal, Parasar and Veldandi, Uday Kiran and Legangneux, Eric (2015) Pharmacokinetic and pharmacodynamic interaction of siponimod (BAF312) and propranolol in healthy subjects. International Journal of Clinical Pharmacology and Therapeutics, 53 (10). pp. 855-865. ISSN 0946-1965

Biswal, Shibadas and Polus, Florine and Pal, Parasar and Veldandi, Uday Kiran and Legangneux, Eric (2015) Pharmacokinetic and pharmacodynamic interaction of siponimod (BAF312) and propranolol in healthy subjects. International Journal of Clinical Pharmacology and Therapeutics, 53 (10). pp. 855-865. ISSN 0946-1965

Bizet, Albane and Becker-Heck, Anita and Ryan, Rebecca and Weber, Kristina and Filhol, Emilie and Krug, Pauline and Halbritter, Jan and Linghu, Bolan and Oakeley, Edward James and Bole-Feysot, Christine and Nitschke, Patrick and Serluca-Aegerter, Fabrizio and Schmidt, Swetlana and Lasbennes-Eckerlen, Marie-Christine and Damask, Amy and Yang, Fan and Bouwmeester, Antonius and Valette, Huguette and Pinson, Lucile and Cassuto, Elisabeth and Dubot, Philippe and Soliman, Neveen and Sahel, Jose and Salomon, Remi and Antignac, Corinne and Gubler, Marie-Claire and Chibout, Salah-Dine and Szustakowski, Joseph and Hildebrandt, Friedhelm and Lorentzen, Esben and Sailer, Andreas and Benmerah, Alexandre and Saint-Mezard, Pierre and Saunier, Sophie (2015) Mutations in TRAF3IP1/IFT54 reveal a new role for IFT proteins in microtubule stabilization. Nat Comm. pp. 1-14. ISSN 2041-1723 (Electronic); 2041-1723 (Linking)

Blakeley, Daniel and Sykes, David and Aston, Philip and Charlton, Steven (2015) Simulating the influence of plasma protein on measured receptor affinity in biochemical assays reveals the utility of Schild analysis for estimating compound affinity for plasma proteins. British Journal of Pharmacology, 172 (21). pp. 5037-5049. ISSN 1476-5381

Blanz, Joachim and Delemonte, Thierry and Pearson, David and Luneau, Alexandre and Ritzau, Michael and Gertsch, Werner and Ramstein, Philippe and Dayer, Jerome and Desrayaud, Sandrine and Braun, Elisabeth and Aichholz, Reiner (2015) Micropreparative isolation and NMR structure elucidation of metabolites of a drug candidate from rat bile and urine. Journal of Chromatography B: Biomedical Sciences and Applications, 989. pp. 1-10.

Blatter, Markus and Dunin-Horkawicz, Stanislaw and Grishina, Inna and Maris, Christophe and Thore, Stephane and Maier, Timm and Bindereif, Albrecht and Allain, Frédéric H.-T. (2015) The Signature of the Five-Stranded vRRM Fold Defined by Functional, Structural and Computational Analysis of the hnRNP L Protein. Journal of Molecular Biology.

Bojkovic, Jade and Richie, Daryl and Six, David and Rath, Christopher and Sawyer, William and Dean, Charles (2015) Characterization of an Acinetobacter baumannii lptD Deletion Strain; Permeability Defects and Response to Inhibition of Lipopolysaccharide and Fatty Acid Biosynthesis. Journal of Bacteriology, 198 (4). pp. 731-741. ISSN 1098-5530

Bojkovic, Jade and Richie, Daryl and Six, David and Rath, Christopher and Sawyer, William and Hu, Daniel and Dean, Charles (2015) Characterization of an A. baumannii lptD Deletion Strain; Permeability Defects and Response to Inhibition of Lipopolysaccharide and Fatty Acid Biosynthesis. Journal of Bacteriology, 198 (4). pp. 731-741.

Bold, Guido and Schnell, Christian and Mcsheehy, Paul M.J. and Brueggen, Josef and Mestan, Juergen and Manley, Paul W. and Drueckes, Peter and Burglin, Marion and Duerler, Ursula and Loretan, Jacqueline and Reuter, Robert and Wartmann, Markus and Theuer, Andreas and Bauer-Probst, Beatrice and Martiny-Baron, Georg and Allegrini, Peter Roland and Furet, Pascal and Wood, Jeanette and Littlewood-Evans, Amanda and Goepfert, Arnaud (2015) A novel potent oral series of VEGFR2 inhibitors abrogate tumor growth by inhibiting angiogenesis. Journal of medicinal chemistry, 59 (1). pp. 132-146. ISSN 0022-26231520-4804

Boone, Jonathan and Cooper, Sara and Johnston, Bobby and Arend, Rebecca and Gilchrest, Austin and Oelschlager, Denise and Grizzle, William and McGwin, Gerald and Gangrade, Abhishek and Straughn, J. Michael and Buchsbaum, Donald (2015) Targeting the Wnt/β-catenin pathway in primary ovarian cancer with the porcupine inhibitor WNT974. Laboratory Investigation.

Bornancin, Frederic and Renner, Florian and Touil, Ratiba and Kolb, Yeter and Touil, Ismahane and Rush, James and Smith, Paul and Bigaud, Marc and Zamurovic Ribrioux, Natasa and Junker Walker, Ursula and Burkhart, Christoph and Dawson King, Janet and Regnier, Catherine and Niwa, Satoru and Katopodis, Andreas and Nuesslein-Hildesheim, Barbara and Weckbecker, Gisbert and Zenke, Gerhard and Kinzel, Bernd and Traggiai, Elisabetta and Brenner, Dirk and Brüstle, Anne and St Paul, Michael and McCoy, Kathy D. and Rolink, Antonius and Mak, Tak W and Ohashi, Pamela S and Patel, Dhavalkumar and Calzascia, Thomas (2015) Deficiency in MALT1 paracaspase activity promotes multi-organ inflammation. Journal of Immunology, 194 (8). pp. 3723-3734. ISSN 1550-6606

Bouslimani, Amina and Porto, Carla and Rath, Christopher and Wang, Mingxun and Yurong , Guo and Gonzalez, Antonio and Berg-Lyon, Donna and Ackermann, Gail and Christensen , Gitte Julie Moeller and Teruaki , Nakatsuji and Zhang , Lingjuan and Borkowski , Andrew and Meehan , Michael and Dorrestein , Kathleen and Gallo , Richard and Bandeira, Nuno and Knight , Rob and Alexandrov , Theodore and Dorrestein , Pieter (2015) 3D molecular cartography of the human skin surface. PNAS.

Bradley, Michelle and Brown, Zarin and Charlton, Steven and Cromie, Karen and Dombrecht, Bruno and De Taeye, Severine and Van den Heede, Kim and Van Heeke, Gino and Kent, Toby and Laeremans, Toon and Manini, Jodie and Roobrouck, Annelies and Steffensen, Soren and Vlerick, David and Willis, Jennifer (2015) Potent and efficacious inhibition of CXCR2 signaling by biparatopic nanobodies combining two distinct modes of action. Molecular Pharmacology, 87 (2). pp. 251-262. ISSN 1521-0111

Briard, Emmanuelle and Rudolph, Bettina and Desrayaud, Sandrine and Krauser, Joel and Auberson, Yves (2015) MS565, a SPECT tracer for evaluating the brain penetration of BAF312 (siponimod). ChemMedChem, 10 (6). pp. 1008-1018. ISSN 18607179

Bringer, Pauline and Jensen, Michael Rugaard and Gembarska, Agnieszka (2015) Identification of piggyBac transposon insertions in malignant tumors. Master degree Bio-engineering applied to health, University of Toulouse III.

Brogdon, Jennifer and Loew, Andreas and Thekkat, Pramod and Idamakanti, Neeraja and Engels, Boris and Singh, Reshma and Ezell, Tucker and Zhou, Li and Ramones, Melissa and Li, Na and Maus, Marcela and Johnson, Laura and Scholler, John and June, Carl and Okada, Hideho and Plesa, Gabriela and Patel, Prachi and McGettigan, Shannon and Nace, Arben and Ohkuri, Takayuki and Kosaka, Akemi and Chen, Taylor and Fraietta, Joseph and Kloss, Christopher and Boesteanu, Alina and Cogdill, Alexandria and Seykora, John (2015) Validation of a humanized anti-EGFR variant III chimeric antigen receptor for a Phase I trial of CART-EGFRvIII in glioblastoma. Science Translational Medicine.

Burger, Matthew and Nishiguchi, Gisele and Han, Wooseok and Lan, Jiong and Simmons, Bob and Atallah, Gordana and Ding, Yu and Tamez Jr., Victoriano and zhang, yanchen and mathur, michelle and muller, kristine and Bellamacina, Cornelia and Lindvall, Mika and Zang, Richard and Huh, Kay and Feucht, Paul and Zavorotinskaya, Tatiana and Dai, Yumin and Basham, Steve and Chan, Julie and Ginn, Elaine and Aycinena, Alex and Holash, Jocelyn and Castillo, Joseph and Langowski, John and Wang, Yingyun and Chen, Min and Lambert, Amy and Fritsch, Christine and Kauffmann, Audrey and Pfister-Wagner, Estelle and Vanasse, K. Gary and Garcia, Pablo (2015) Identification of N-(4-((1R,3S,5S)-3-amino-5-methylcyclohexyl)pyridin-3-yl)-6-(2,6-difluorophenyl)-5-fluoropicolinamide (PIM447), a Potent and Selective Proviral Insertion Site of Moloney Murine Leukemia (PIM) 1,2 and 3 Kinase Inhibitor in Clinical Trials for Hematological Malignancies. Journal of Medicinal Chemistry.

Busby, Scott (2015) MALDI High-Throughput Screening beyond 100,000 Samples per Day in Drug Discovery. Bruker Poster Note PN-05.

Busche, Marc Aurel and Adelsberger, Helmuth and Kekus, Maja and Förstl, Hans and Nelken, Israel and Konnerth, Arthur (2015) Breakdown of slow-wave oscilliations in mouse modles of Alzheimer's disease. Nature Neuroscience.

Busche, Marc Aurel and Grienberger, Christine and Keskin, Aylin Derya and Song, Beomjong and Neumann, Ulf and Staufenbiel, Matthias and Förstl, Hans and Konnerth, Arthur (2015) Decreased amyloid-β but increased neuronal hyperactivity by immunotherapy in Alzheimer´s models. Nature Neuroscience.

Bushee, Jennifer and Dunne, Christine and Argikar, Upendra (2015) An in vitro approach to investigate ocular metabolism: Part II - Betaxolol. Xenobiotica.

Butler, Rebecca and Smith, Nichola and Hunt, Thomas (2015) ENaC Inhibitors for the Treatment of Cystic Fibrosis. Pharmaceutical Patent Analysis.

C

Camargo, Miguel and Zhang, X D and Loerch, Patrick and Caceres, RM and Marine, SD and UVa, P and Ferrer, M and Majercak, J and Ray, WJ and Yi-An, C and Shearman, MS and Mizuguchi, Kenji (2015) PATHWAY-BASED ANALYSIS OF GENOME-WIDE SIRNA SCREENS REVEALS THE REGULATORY LANDSCAPE OF APP PROCESSING. PLOS ONE, 10 (2). ISSN 1932-6203

Camenisch, Gian P. and Poller, Birk and Kunze, Annett and Huwyler, Jörg (2015) Application of the extended clearance concept classification system (ECCCS) to predict the victim drug-drug interaction potential of statins. Drug Metabolism and Personalized Therapy, 30 (3). pp. 175-188. ISSN 23638915

Camenisch, Gian P. and Riede, Julia and Kunze, Annett and Huwyler, Jörg and Poller, Birk and Umehara, Ken-Ichi (2015) The extended clearance model and its use for the interpretation of hepatobiliary elimination data. ADMET&DMPK.

Canapari, CA and Barrowman, N and Hoey, L and Walker, SW and Townsend, E and Tseng, BS and Katz, SL (2015) Truncal Fat Distribution Correlates With Decreased Vital Capacity in Duchenne Muscular Dystrophy. Pediatric Pulmonology. pp. 63-70.

Carballido, Jose and Regairaz Kalenga Kapiamba, Camille and Raad, Layla and Rauld, Celine (2015) IL17A/CCR6 expression in human T cells. Lab meeting at D-BSSE, Basel.

Carson, Cheryl and Raman, Pichai and Tullai, Jennifer and Xu, Lei and Henault, Martin and Thomas, Emily and Yeola, Sarita and Lao, Jianmin and McPate, Mark and Verkuyl, J Martin and Marsh, George and Sarber, Jason and Amaral, Adam and Bailey, Scott and Lubicka, Danuta and Pham, Helen and Miranda, Nicolette and Ding, Jian and Tang, Hai-Ming and Ju, Haisong and Tranter, Pamela and Ji, Nan and Krastel, Philipp and Jain, Rishi K and Schumacher, Andrew M and Loureiro, Joseph J and George, Elizabeth and Berellini, Giuliano and Ross, Nathan T and Bushell, Simon M and Erdemli, Gül and Solomon, Jonathan M (2015) Englerin A Agonizes the TRPC4/C5 Cation Channels to Inhibit Tumor Cell Line Proliferation. PloS one, 10 (6). e0127498. ISSN 1932-6203

Castanotto, Daniela and Lin, Min and Kowolik, Claudia and Wang, LiAnn and Ren, Xiao-Qin and Soifer, Harris and Koch, Troels and Hansen, Bo Rode and Armstrong, Brian and Wang, Zhigang and Bauer, Paul and Rossi, John and Stein, CA (2015) A cytoplasmic pathway for gapmer antisense oligonucleotide-mediated gene silencing in mammalian cells. Science Advances, 43 (19). pp. 9350-9361. ISSN 1362-4962

Chalmin, Fanny and Rochemont, Viviane and Lippens, Carla and Clottu, A and Sailer, Andreas and Merkler, Doron and Hugues, Stephanie and Pot, Caroline (2015) Oxysterols regulate CD4+ T cell trafficking during experimental autoimmune encephalomyelitis. Journal of Autoimmunity, 56. pp. 45-55.

Chandramouli, Sumana and Ciferri, Claudio and Gerrein, Rachel and Nikitin, Pavel and Calo', Stefano and Balabanis, Kara and Settembre, Ethan and Monroe, James and Hebner, Christy and Carfi, Andrea (2015) Structure of HCMV glycoprotein B in the postfusion conformation bound to a neutralizing human antibody. Nature Communications, 6. ISSN 2041-1723

Chappuis, Quentin and Bornet, Aurelien and Milani, Jonas and Vichoud, Basile and Gossert, Alvar and Bodenhausen, Geoffrey and Jannin, Sami (2015) The Preparation of Hyperpolarized Water and its Use to Enhance "waterLOGSY" Drug Screening. J Phys Chem Lett, 6 (9). pp. 1674-1678. ISSN 1948-7185

Chatterji, Udayan and Garcia-Rivera, Jose A. and Baugh, James and Gawlik, Katarzyna and Wong, Kelly and Zhong, Weidong and Brass, Cliff and Naoumov, Nikolai and Gallay, Philippe A. (2015) The combination of alisporivir plus an NS5A inhibitor provides additive to synergistic anti-hepatitis C virus activity without detectable cross-resistance,. Antimicrobial Agents and Chemotherapy.

Chen, Jin and Bhansali, Suraj and Neelakantham, Srikanth Raju and Trusley, Craig and Majumdar, Tapan and Rebello, Sam and Sunkara, Gangadhar and Meyers, Charles (2015) Effect of Pradigastat, a Diacylglycerol Acyltransferase 1 Inhibitor, on the Pharmacokinetics of a Combination Oral Contraceptive in Healthy Female Subjects. International journal of clinical pharmacology and therapeutics, 53 (4). pp. 317-324. ISSN 0946-1965

Chen, Jin and Bhansali, Suraj and Neelakantham, Srikanth Raju and Trusley, Craig and Majumdar, Tapan and Rebello, Sam and Sunkara, Gangadhar and Meyers, Charles (2015) Effect of pradigastat, a diacylglycerol acyltransferase 1 inhibitor, on the pharmacokinetics of a combination oral contraceptive in healthy female subjects. International Journal of Clinical Pharmacology and Therapeutics, 53 (4). pp. 317-324. ISSN 0946-1965

Chen, Qiuyan and Vishnivetskiy, Sergey A. and Zhuang, Tiandi and Cho, Min-Kyu and Thaker, Tarjani M. and Sanders, Charles R. and Gurevich, Vsevolod V. and Iverson, T. M. (2015) The Rhodopsin-Arrestin-1 Interaction in Bicelles. Methods in molecular biology, 1271. pp. 77-95. ISSN 1940-6029; 1064-3745

Chen, Yen Liang and Shi, Pei-Yong and Yokokawa, Fumiaki (2015) Nucleoside inhibitors of dengue virus. Antiviral Research, 122. pp. 12-19. ISSN 01663542

Chitnis, Shripad and Kulmatycki, Kenneth and Han, Yi and Sunkara, Gangadhar and Yamaguchi, Masayuki and Nozaki, Sachiko and Zhao, Rong (2015) Population pharmacokinetic modeling and noncompartmental analysis demonstrated bioequivalence between metformin component of metformin/vildagliptin fixed-dose combination products and metformin immediate-release tablet sourced from various countries. Clinical Pharmacology in Drug Developement, 5 (1). pp. 40-51.

Choi, Vivian and Bigelow, Chad and Mcgee, Terri and Gujar, Akshata and Li, Hui and Hanks, Shawn and Vrouvlianis, Joanna and Maker, Michael and Leehy, Barrett and Zhang, Yiqin and Aranda, Jorge and Bounoutas, George and Demirs, John and Yang, Junzheng and Richard, Ornberg and Wang, Yu and Martin, Wendy and Stout, Kelly and Argentieri, Gregory and Grosenstein, Paul and Diaz, Danielle and Turner, Oliver and Jaffee, Bruce and Police, Seshidhar and Dryja, Ted (2015) AAV-mediated RLBP1 gene therapy improves the rate of dark adaption in Rlbp1 knockout mice. AAV-mediated RLBP1 gene therapy improves the rate of dark adaption in Rlbp1 knockout mice.

Christ, Andreas Dominik and Soldermann, Nicolas (2015) An open-label, non-randomized, within-patient dose-finding study followed by a randomized, double-blind placebo controlled study with extension to assess the safety and efficacy of CDZ173 in patients with APDS/PASLI (Activated phosphoinositide 3-kinase delta syndrome/ p110δ-activating mutation causing senescent T cells, lymphadenopathy and immunodeficiency). Part of a CRADA with NIH, thus NIH will be allowed to make the abstract publicly available.

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Evans, Chris and Arnold, Mark and Bryan, Peter and Duggan4, Jeffrey and James5, Chris and Li, Wenkui and Lowes, Steve and Matassa, Luca and Olah, Timothy and Timmerman, Philip and Wang, Xiaomin and Wickremsinhe, Enaksha and Williams, John and Woolf, Eric and Zane, Patricia (2015) Implementing Dried Blood Spot Sampling for Clinical Pharmacokinetic Determinations; Considerations from the IQ Consortium Microsampling Working Group. AAPS Journal.

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Francotte, Eric and DESFONTAINE, Vincent and GUILLARME, Davy and Novakova, Lucie (2015) Supercritical fluid chromatography in pharmaceutical analysis. Journal of Pharmaceutical and Biomedical Analysis, 113. pp. 56-71. ISSN 07317085

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Gabrielsson, Johan and Hjorth, Stephan and Vogg, Barbara and Harlfinger, Stephanie and Gutierrez, Pablo and Peletier, Lambertus and Pehrson, Rikard and Davidsson, Pia (2015) Modeling and Design of Challenge Tests: Inflammatory and Metabolic Biomarkers. Modeling and Design of Challenge Tests: Inflammatory and Metabolic Biomarkers .

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Gaul, Christoph and Radimerski, Thomas and Vangrevelinghe, Eric and Baffert, Fabienne and Hofmann, Francesco and Murakami, Masato and Sterker, Dario and Doelemeyer, Arno and Romanet, Vincent and Andraos-Rey, Rita and Ebel, Nicolas and Mandon, Emeline and Zender, Michael and Weinstock, David M. and Letai, Anthony and Sallan, Stephen E. and Silverman, Lewis and Eck, Michael J. and Rodig, Scott J. and Wu, Shuo-Chieh and Li, Loretta S. and Kopp, Nadja and Montero, Joan and Chapuy, Bjoern and Christie, Amanda L. and Liu, Huiyun and Christodoulou, Alexandra and van Bodegom, Diederik and Tivey, Trevor and Lane, Andrew A. and Ryan, Jeremy A. and Yoda, Akinori and DeAngelo, Daniel and Stone, Richard M. and Steensma, David and Wadleigh, Martha and Harris, Marian (2015) Type II JAK2 inhibition in B-cell acute lymphoblastic leukemia. Cancer Cell, 28 (1). pp. 29-41.

Geier, Martina and Bachler, Thorsten and Hanlon, Steven P. and Eggimann, Fabian and Kittelmann, Matthias and Weber, Hansjörg and Luetz, Stephan and Wirz, Beat and Winkler, Margit (2015) Human FMO2-based microbial whole-cell catalysts for drug metabolite synthesis. Journal Microbial Cell Factories, 14 (82).

Gerspacher, Marc and Fairhurst, Robin and Mah, Robert and Roehn-Carnemolla, Esther and Furet, Pascal and Fritsch, Christine and Guthy, Daniel Alexander (2015) Discovery of a Novel Tricyclic 4H-Thiazolo[5',4':4,5]pyrano[2,3-c]pyridine-2-amino Scaffold and its Application in a PI3K Inhibitor with High PI3K Isoform Selectivity and Potent Cellular Activity. Bioorg. Med. Chem. Letters, 25 (17). pp. 3582-3584. ISSN 0960-894X

Gerspacher, Marc and Imbach-Weese, Patricia and Mah, Robert and Caravatti, Giorgio and Furet, Pascal and Fritsch, Christine and Schnell, Christian and Blanz, Joachim and Blasco, Francesca and Desrayaud, Sandrine and Guthy, Daniel Alexander and Knapp, Mark and Arz, Dorothee and Wirth, Jasmin and Roehn-Carnemolla, Esther and Luu, Van Huy (2015) Identification and optimisation of 4,5-dihydrobenzo[1,2-d:3,4-d]bisthiazole and 4,5-dihydrothiazolo[4,5-h]quinazoline series of selective phosphatidylinositol-3 kinase alpha inhibitors. Bioorganic and Medicinal Chemistry Letters, 25. pp. 3575-3581. ISSN 0960-894X

Gessier, Francois and Kallen, Joerg and Jacoby, Edgar and Chene, Patrick and Valat, Therese-Marie and Ruetz, Stephan and Jeay, Sebastien and Holzer, Philipp and Masuya, Keiichi and Furet, Pascal (2015) Discovery of dihydroisoquinolinone derivatives as novel inhibitors of the p53-MDM2 interaction with a distinct binding mode. Bioorganic & Medicinal Chemistry Letters, 25 (17). pp. 3621-3625. ISSN 0960894X

Ghode, Pramila Baban and Sivaraman , Jayaraman and Chacko , Jobichen and Bifani, Juan Pablo (2015) Crystallization of uracil phosphoribosyltransferase (MtUPRT) from Mycobacterium tuberculosis. Biochemical and biophysical research communications : BBRC, 467 (3). pp. 577-582. ISSN 0006291X

Glowienke, Susanne (2015) Establishing best practise in the application of expert review of mutagenicity under ICH M7. Regulatory Toxicology and Pharmacology.

Goldberg, Hilary and Harari, Sergio and Cottin, Vincent and Rosas, Ivan and Peters, Elizabeth and Biswal, Shibadas and Cheng, Yi and Khindri, Sanjeev and Kovarik, John M. and Ma, Shenglin and McCormack, Francis and Henske, Elizabeth (2015) Everolimus for the treatment of lymphangioleiomyomatosis: A phase II study. European Respiratory Journal, 46 (3). pp. 783-794. ISSN 1399-3003

Gonzalez-Sandoval, Adriana and D. Towbin, Benjamin and Gaidatzis, Dimos and Geng, Liqing and Wang, Li and Yang, Teddy and Zhao, Kehao and Gasser, Susan (2015) Perinuclear Anchoring of H3K9-Methylated Chromatin Stabilizes Induced Cell Fate in C. elegans Embryos. Cell.

Green, Alexa/S and Maciel, Thiago/T and Hospital, Marie-Anne and Yin, Chae and Townsend, Elizabeth/C and Pilorge, Sylvain and Jacquel, Arnaud and Lambert, Mireille and Paubelle, Etienne and Zylbersztejn, Florence and Decroocq, Justine and Kosmider, Olivier and Auberger, Patrick and Hermine, Olivier and Weinstock, David/M and Lacombe, Catherine and Mayeux , P and Vanasse, K. Gary and Leung, Anscar Y and Moura, IC and Bouscary, Didier and Tamburini, Jerome (2015) Pim kinases modulate resistance to tyrosine kinase inhibitors in FLT3-ITD acute myeloid leukemia. Science Advances, 1 (8). e1500221. ISSN 2375-2548

Grosskreutz, Cynthia and Brigell, Mitchell and Letko, Eric and Yeh, Stephen and Foster, C. Stephen and Pleyer, Uwe (2015) Efficacy and Safety of Intravenous Secukinumab in Noninfectious Uveitis Requiring Steroid-Sparing Immunosuppressive Therapy. Ophthalmology, 122 (5). pp. 939-948. ISSN 1549-4713

Grosskreutz, Cynthia and Hockey, Hans-Ulrich and Serra, Denise and Dryja, Ted (2015) Dry eye signs and symptoms persist during systemic neutralization of IL-1β by canakinumab or IL-17A by secukinumab. Cornea, 34 (12). pp. 1551-1556.

Grunewald, Jan and Klock, Heath and Cellitti, Susan and Bursulaya, Badry and Mcmullan, Daniel and Jones, David and Chiu, Hsien-Po and Patterson, Paula and Zhou, Huanfang and Vance, Julie and Nigoghossian, Edward and Tong, Hung and Daniel, Dylan and Mallet, William and Ou, Weijia and Uno, Tetsuo and Brock, Ansgar and Lesley, Scott and Geierstanger, Bernhard (2015) Efficient preparation of site-specific antibody-drug conjugates using phosphopantetheinyl transferases. Bioconjugate Chemistry, 26 (12). pp. 2554-2562. ISSN 1520-4812

Gueret, Stephanie and Wagner, Beatrix (2015) A Cyclic Carbo-Isosteric Penta-Depsipeptide: cyclo(Phe1–D-Ala2–Gly3–Phe4–APO5). Acta Crystallographica Section E, E71. pp. 113-116.

Guthertz, Nicolas and Klopp, Julia and Winterhalter, Aurelie and Fernandez, Cesar and Gossert, Alvar (2015) Auto-inducing media for uniform isotope labeling of proteins with 15N, 13C and 2H. Journal of Biomolecular NMR, 62 (2). pp. 169-177.

Guthy, Daniel Alexander and Voshol, Johannes (2015) Antibody-based arrays in disease proteomics. Antibody Technology Journal.

Gutmann, Sascha and Hinniger, Alexandra and Fendrich, Gabriele and Drueckes, Peter and Antz, Sylvie and Mattes, Henri and Moebitz, Henrik and Ofner, Silvio and Schmiedeberg, Niko and Stojanovic, Aleksandar and Rieffel, Sebastien and Strauss, Andre and Troxler, Thomas J. and Sparrer, Helmut and Glatthar, Ralf (2015) The Crystal structure of the cancer osaka thyroid kinase reveals an unexpected kinase domain fold. The Journal of Biological Chemistry, 290 (24). ISSN 0021-92581083-351X

Göke, Friederike and Franzen, Alina and Hinz, Trista and Yoon, Petros and Marek4, Lindsay and Sharma, Rakesh and Bode, Maike and Maessenhausen, Anne and Lankat-Buttgereit, Brigitte and Göke, Antonia and Golletz, Carsten and Kirsten, Robert and Boehm, Diana and Vogel, Wenzel and Kleczko, Emily and Eagles-Soukup, Justin and Hirsch, Fred and Bremen, Tobias and Bootz, Friedrich and Schroeck, Andreas and Tan, Aik-Choon and Jimeno, Antonio and Heasley, Lynn and Perner, Sven (2015) FGFR1 expression levels predict BGJ398 Sensitivity of FGFR1-dependent head and neck Squamous cell cancers. Clinical Cancer Research, 21 (19). pp. 4356-4364. ISSN 15573265

Göke, Friederike and Franzen, Alina and Sharma, Rakesh and Bode, Maike and von Maessenhausen, Anne and Heasley, Lynn E and Perner, Sven (2015) FGFR1 expression, not gene amplification, predicts FGFR inhibitor sensitivity in head and neck squamous cell cancer cells. Clinical cancer research, 21 (19). pp. 4356-4364. ISSN 26015511

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Harwood, Iain and Rooney, Lisa (2015) Towards Novel 1,2,4,5-Tetrazine Mediated Peptide Macrocyclisations. PhD Thesis to be submitted to University of Edinburgh.

Haver, Hana and Chua, Adeline and Ghode, Pramila Baban and Lakshminarayana, Suresh Bangalore and Singhal, Amit and Mathema, Barun and Wintjens, Rene and Bifani, Juan Pablo (2015) Mutations in the F420 biosynthetic pathway and a nitroreductase enzyme are the primary resistance determinants in PA-824 spontaneous mutants in Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy, 59 (9). pp. 5316-5323. ISSN 0000-0000

Haynes, Katelin R. and Thomas, Gethin P. and Brown, Matthew A. and Kneissel, Michaela and Glant, Tibor T. (2015) Treatment of a mouse model of ankylosing spondylitis with exogenous sclerostin has no effect on disease progression. BMC Musculoskeletal Disorders, 16 (1). ISSN 1471-2474

He, Jing and Hamann, Lawrence and Davies, Huw and Beckwith, Rohan (2015) Late-stage C-H functionalization of complex alkaloids & drug molecules via intermolecular rhodium-carbenoid insertion. Nature Communications.

Hechinger, Anne-Kathrin and Smith, Benjamin and Flynn, Ryan and Hanke, Kathrin and McDonald-Hyman, Cameron and Taylor, Patricia A and Pfeifer, Dietmar and Hackanson, Björn and Leonhardt, Franziska and Prinz, Gabriele and Dierbach, Heide and Schmmitt-Gräff, Annette and Kovarik, Jiri and Blazar, Bruce and Zeiser, Robert (2015) Therapeutic activity of multiple common g-chain cytokine inhibition in acute and chronic GVHD. Blood, 125 (3). pp. 570-580.

Heining, Peter and Ruysschaert, Tristan (2015) THE USE OF MINIPIG IN DRUG DISCOVERY AND DEVELOPMENT; Pros and cons of minipig selection and strategies to use as a preferred non-rodent species. Journal of Toxicologic Pathology, 44 (3). pp. 467-473. ISSN 0192-62331533-1601

Helliwell, Stephen and Abraham, Yann and Movva, Rao and Filipuzzi, Ireos and Stahl, Michael and Rispal, Delphine and Eltschinger, Vaga and Bodenmiller, Bernd and Aebersold, Ruedi and Loewith, Robbie and Vaga, Stefania (2015) Sphingolipids mediate the signals for all the essential functions of Target Of Rapamycin Complex 2. Journal of Biological Chemistry, tba (o.

Hirano, Masaru and Meyers, Charles and Golla, Ganga Raju and Pal, Parasar and Pinot, Pascale and Lin, Tsu-Han and Majumdar, Tapan and Rebello, Sam and Sunkara, Gangadhar and Chen, Jin (2015) Effect of Hepatic Impairment on the Pharmacokinetics of Pradigastat, a Diacylglycerol Acyltransferase-1 (DGAT1) Inhibitor. Clinical Pharmacokinetics, 54 (7). pp. 761-770. ISSN 0312-5963

Hoepfner, Dominic and Krastel, Philipp and Schirle, Markus and Schmitt, Esther and Roggo, Silvio (2015) Nannocystin A: an Elongation Factor 1 Inhibitor from Myxobacteria with Differential Anti-Cancer Properties. Angewandte Chemie Int Edition, 54 (35). pp. 10149-10154. ISSN 14337851

Hoffmann, Peter (2015) The Evaluation of Drug-induced Changes in Cardiac Inotropy in Dogs: results from a HESI-sponsored consortium. J Pharmacol Toxicol Methods. 2015 Sep-Oct;75:70-90. doi: 10.1016/j.vascn.2015.02.002. Epub 2015 Apr 3.

Holenstein, Fabian and Christer, Eriksson and Ioanna, Erlandsson and Nils , Norrman and Jill, Simon and Ake , Danielsson and Milicov, Adriana and Schindler, Patrick and Schlaeppi, Jean-Marc (2015) Automated harvesting and 2-step purification of unclarified mammalian cell-culture broths containing antibodies. Journal of Chromatography A, 1418. pp. 103-109. ISSN 18733778

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van Ersel, Janet and Stevens, Claire H and Przybyla, Magdalena and Gladbach, Amadeus and Stefanoska, Kristie and Chan, Chesed and Xin, Kai and Ong, Wei Yi and Hodges, John R and Sutherland, Greg T and Kril, Jilian J and Abramowski, Dorothee and Staufenbiel, Matthias and Halliday, Glenda M and Ittner, Lars M (2015) Early-onset Axonal Pathology in a Novel P301S-Tau Transgenic Mouse Model of Frontotemporal Dementia. Neuropathology Appl Neurobiol..

van der Sar, Sonia A and Zielman, Ronald and Terwindt, Gisela M and van den Maagdenberg, Arn M J M and Deelder, André M and Mayboroda, Oleg A and Meissner, Axel and Ferrari, Michel D (2015) Ethanol contamination of cerebrospinal fluid during standardized sampling and its effect on (1)H-NMR metabolomics. Analytical and bioanalytical chemistry, 407 (16). pp. 4835-4839. ISSN 1618-2650

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Wallace, Owen and Arrowsmith, John and Leach, Andrew and Leeson, Paul and Mandrell, Sam and Owen, Robert and Pairaudeau, Garry and Pennie, William and Pickett, Stephen and Wang, Jibo and Waring, Michael and Weir, Alex (2015) A comprehensive analysis of development attrition in drug candidates from four major pharmaceutical companies. Nature Reviews Drug Discovery.

Wang, Qingyin and Dong, Hongping and Zou, Bin and Karuna, Ratnaningrum and Wan, Kah Fei and Zou, Jing and Susila, Agatha and Yip, Jin Teen and Xu, Haoying and Ding, Mei and Chan, Wai Ling and Gu, Feng and Seah, Peck Gee and Liu, Wei and Lakshminarayana, Suresh Bangalore and Kang , Congbao and Julien, Lescar and Blasco, Francesca and Smith, Paul William and Shi, Pei-Yong (2015) Discovery of dengue virus NS4B inhibitors. Journal of Virology, 89 (16). pp. 8233-8244. ISSN 1098-5514

Warth, Rainer and Salathé, Michelle and Magnin, Annette and Berardi, Simona and Imbert, Georges and Stadelmann, Marie-Monique and Perren, Aurel (2015) Erneuerte Vorlagen für Biobanken-Reglement, Information und Einwilligung: Ausarbeitung von schweizweiten Vorlagen für Biobanken-Reglement, Information und Einwilligung. Schweizerische Ärztezeitung | Bulletin des médecins suisses | Bollettino dei medici svizzeri, 96 (23). pp. 821-823. ISSN 0036-7486

Wassermann, Anne and Lounkine, Eugen and Davies, John and Glick, Meir and Camargo, Miguel (2015) The opportunities of mining historical and collective data in drug discovery. Drug Discovery Today, 20 (4). pp. 422-434. ISSN 13596446

Wassermann, Anne and Lounkine, Eugen and Le Goff, Gaelle and King, Frederick and Hoepfner, Dominic and Peltier, John and Grippo, Melissa and Prindle, Vivian and Tao, Jianshi and Schuffenhauer, Ansgar and Wallace, Iain and Chen, Shanni and Krastel, Philipp and Cobos-Correa, Amanda and Parker, Christian and Davies, John and Glick, Meir (2015) Dark chemical matter – could “inactive” compounds be good starting points for lead discovery? Nature Chemical Biology, 11 (12). pp. 958-966. ISSN 1552-44501552-4469

Weisberg, Ellen and Halilovic, Ensar and Cooke, Vesselina and Nonami, Atsushi and Ren, Tao and Sanda, Takaomi and Simkin, Irene and Yuan, Jing and Antonakos, Brandon and Barys, Louise and Ito, Moriko and Cowens, Kristen and Nelson, Erik and Sattler, Martin and Jeay, Sebastien and Wuerthner, Jens and McDonough, Sean and Wiesmann, Marion and Griffin, James (2015) Inhibition of wild-type p53-expressing AML by novel small molecule HDM2 inhibitor, CGM097. Mol Cancer Ther, 14 (10). pp. 2249-2259. ISSN 1538-8514

Weisberg, Ellen and Halilovic, Ensar and Cooke, Vesselina and Nonami, Atsushi and Ren, Tao and Sanda, Takaomi and Simkin, Irene and Yuan, Jing and Antonakos, Brandon and Barys, Louise and Ito, Moriko and Cowens, Kristen and Nelson, Erik and Sattler, Martin and Jeay, Sebastien and Wuerthner, Jens U. and McDonough, Sean M. and Wiesmann, Marion and Griffin, James D. (2015) Inhibition of wild-type p53-expressing AML by the novel small molecule HDM2 inhibitor CGM097. Molecular Cancer Therapeutics, 14 (10). pp. 2249-2259. ISSN 1538-8514

Welink, Jan and Fluhler, Eric and Hughes, Nicola and Arnold, Mark and Garofolo, Fabio and Booth, Brian and Bustard, Mark and Coppola, Laura and Dhodda, Raj and Evans, Christopher and Gleason, Carol and Haidar, Sam and Hayes, Roger and Heinig, Katja and Katori, Noriko and Le Blaye, Olivier and Li, Wenkui and Liu, Guowen and Santos, Gustavo Mendes Lima and Meng, Min and Nicholson, Bob and Savoie, Natasha and Skelly, Michael and Sojo, Luis and Tampa, Nilufer and van de Merbel, Nico and Verhaeghe, Tom and Vinter, Stephen and Wickremsinhe, Enaksha and Whale, Emma and Wilson, Amanda and Witte, Bärbel and Woolf, Eric (2015) 2015 White Paper on Recent Issues in Bioanalysis: Focus on New Technologies & Biomarkers (Part 1 – Small Molecule by LCMS). Bioanalysis.

Welzenbach, Karl and Mancuso, Riccardo and Krähenbühl, Stephan and Weitz-Schmidt, Gabriele (2015) A novel multi-parameter whole blood assay to dissect the pharmacologic effects of different modes of LFA-1 receptor occupancy. British Journal of Pharmacology.

Wendling, Thierry and Dumitras, Swati and Woessner, Ralph and Pigeolet, Etienne and Ogungbenro, Kayode and Aarons, Leon (2015) Application of a Bayesian population approach to physiological modelling of mavoglurant pharmacokinetics. Journal of Pharmacokinetics and Pharmacodynamics.

Werfel, Thomas and Heratizadeh, Annice and Niebuhr, Margarete and Kapp, Alexander and Karch, Annika and Erpenbeck, Veit and Loesche, Christian and Jung, Thomas and Krug, Norbert and Badorrek, Philipp and Hohlfeld, Jens M (2015) Exacerbation of atopic dermatitis upon grass pollen exposure in an environmental challenge chamber. J Allergy Clin Immunol.

Wilson, Stephen C. and Baryza, Jeremy and Reynolds, Aimee and Bowman, Keith and Keegan, Mark E. and Standley, Stephany and Gardner, Noah and Parmar, Parul and Agir, Vahide and Yadav, Sunita and Zunic, Adnan and Vargeese, Chandra and Lee, Cameron and Rajan, Srinivasan (2015) Real Time Measurement of PEG Shedding from Lipid Nanoparticles in Serum via NMR Spectroscopy. Molecular Pharmaceutics.

Winkler, Gian Christian and Perino, Christopher and Araya, Selene Hilda and Bechter, Rudolf and Kuster, Martin and Lovsin Barle, Ester (2015) Workshop Report Classification of Dermal Sensitizers in Pharmaceutical Manufacturing. Regulatory Toxicology and Pharmacology, 72 (-). pp. 501-505. ISSN 0273-2300

Wlodarska, Marta and Kostic, Aleksandar / D and Xavier, Ramnik / J (2015) An integrative view of microbiome-host interactions in inflammatory bowel diseases. Cell Host and Microbe, 17 (5). pp. 577-591. ISSN 19346069

Wolf, Romain (2015) Extracting Ligands from Receptors by Reversed Targeted Molecular Dynamics. Journal of Chemical Information and Modeling.

wagner, John and brunstein, claudio and Boitano, Anthony and DeFor, Todd and McKenna, David and Sumstad, Darin and Blazar, Bruce and Tolar, Jakub and Le, Chap and Jones, Julie and Cooke, Michael and Bleul, Conrad (2015) Safety and Efficacy of StemRegenin-1 Expanded Umbilical Cord Blood Hematopoietic Cells after Myeloablative Conditioning. Cell Stem Cell.

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Xie, Xuping and Zou, Jing and Dong, Hongping and Shi, Pei-Yong (2015) Determinants of dengue virus NS4A protein oligomerization. Journal of Virology, 89 (12). pp. 6171-6183. ISSN 0022-538X

Xie, Xuping and Zou, Jing and Yuan, Zhiming and Shi, Pei-Yong (2015) Two distinct sets of NS2A molecules are responsible for dengue virus RNA synthesis and virion assembly. Journal of Virology, 89 (2). pp. 1298-1313. ISSN 1098-5514

Xu, Xiang and Choi, Sung Hee and Hu, Tiancen and Aster, Jon and Chopra, Rajiv and Fryer, Christy and Blacklow, Stephen (2015) Insights into autoregulation of Notch 3 from Structural and Functional Studies of its negative Regulatory Region. tbd.

Y

Yan, Jing and Almilaji, Ahmad and Schmid, Evi and Shimshek, Derya and Van Der Putten, P. Herman and Wagner, Carsten and Shumilina, Ekaterina and Lang, Florian (2015) LRRK2 sensitive Na+/Ca2+ exchanger activity in dendritic cells. The Federation of American Societies for Experimental Biology Journal.

Yan, Kelly and Merritt, Hanne and Crawford, Kenneth and Pardee, Gwynn and Cheng, Jan Marie and Widger, Stephania and Hekmat-Nejad, Mohammad and Zaror, Isabel and Sim, Janet (2015) Expression, Purification and Characterization of Inactive and Active Forms of ERK2 from Insect Expression System. Protein Expression and Purification.

Yeo, Kim Long and Chen, Yen Liang and Xu, Haoying and Dong, Hongping and Wang, Qingyin and Yokokawa, Fumiaki and Shi, Pei-Yong (2015) Synergistic suppression of dengue virus replication using a combination of nucleoside analogs and nucleoside synthesis inhibitors. Antimicrobial Agents and Chemotherapy, 59 (4). pp. 2086-2093.

Yu, Hongbin and Balani, Suresh and Chen, Weichao and Cui, Donghui and He, Ling and Humphreys, H. Griffith and Mao, Jialin and Lai, George and Lee, Anthony and Lim, Heng-Keang and MacLauchlin, Christopher and Prakash, Chandra and Surapeneni, Sekhar and Tse, Susanna and Upthagrove, Alana and Walsky, Robert and Wen, Bo and Zheng, Zhaopie (2015) Contribution of Metabolites to P450 Inhibition-Based Drug-Drug Interactions: Scholarship from the IQ DMLG Metabolite Group. Drug Metabolism and Disposition.

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Zaiss, Mario M. and Rapin, Alexis and Lebon, Luc and Dubey, Lalit Kumar and Mosconi, Ilaria and Sarter, Kerstin and Piersigilli, Alessandra and Menin, Laure and Walker, Alan W. and Rougemont, Jacques and Oonagh, Paerewick and Geldhof, Peter and McCoy, Kathleen D. and Macpherson, Andrew and Croese, John and Giacomin, Paul R. and Loukas, Alex and Junt, Tobias and Marsland, Benjamin and Harris, Nicola L. (2015) Intestinal helminths modulate allergic inflammation by altering microbial metabolism. Immunity.

Zhang, M and Eismin, R and Kenttamaa, H and Xiong, H and Wu, Y and Burdette, D and Urbanek, R (2015) Identification of 2-aminothiazolobenzazepine metabolites in human, rat, dog, and monkey microsomes by ion-molecule reactions in linear quadrupole ion trap mass spectrometry. Drug Metabolism and Disposition. pp. 358-366.

Zhang, Tao and Heimbach, Tycho and Zhang, Jin and Lin, Wen and He, Handan (2015) Prospective Predictions of Human Pharmacokinetics for Eighteen Compounds. Journal of Pharmaceutical Sciences, 104 (9). pp. 2795-2806. ISSN 1520-6017

Zhang, Tao and Heimbach, Tycho and Zhang, Jin and Lin, Wen and He, Handan (2015) Prospective Predictions of Human Pharmacokinetics for Eighteen Compounds. Journal of Pharmaceutical Sciences, 104 (9). pp. 2795-2806. ISSN 1520-6017

Zhao, Yuan and Li, Jue and Gu, Hui and Wei, DongQing and Fu, Wei and Yu, Zhengtian (2015) Conformational Preferences of π-π Stacking Between Ligand and Protein, Analysis Derived from Crystal Structure Data Geometric Preference of π-π Interaction. Interdisciplinary sciences, computational life sciences, 7 (3). pp. 211-220. ISSN 1867-1462

Zhao, Yuan and Li, Jue and Gu, Hui and Wei, Dongqing and Xu, Yao-chang and Fu, Wei (2015) Conformational Preferences of π-π stacking between ligand and protein, Analysis derived from Crystal Structure Data. Interdisciplinary Sciences: Computational Life Sciences, 7. pp. 211-220.

Zou, Bin and Seh Yong, Leong and Ding, Mei and Smith, Paul William (2015) A mild and efficient synthesis of spiroquinolinones via an unexpected rearrangement. Tetrahedron Letters, 56 (44). pp. 6016-6018. ISSN 1873-3581

Zou, Jing and Xie, Xuping and Wang, Qingyin and Dong, Hongping and Lee, Michelle Yueqi and Kang, Congbao and Yuan, Zhiming and Shi, Pei-Yong (2015) Characterization of Dengue virus NS4A and NS4B protein interaction. Journal of Virology, 89 (7). pp. 3455-3470. ISSN 1098-5514

This list was generated on Mon Dec 9 05:21:26 2019 UTC.

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