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Nucleoside inhibitors of dengue virus

Chen, Yen Liang and Shi, Pei-Yong and Yokokawa, Fumiaki (2015) Nucleoside inhibitors of dengue virus. Antiviral Research, 122. pp. 12-19. ISSN 01663542

Abstract

Nucleoside analogs represent the largest class of antiviral agent and have been actively pursued for potential dengue virus (DENV) therapy. Here we review (i) the nucleoside analogs with known anti-DENV activities; (ii) challenges of the nucleoside antiviral approach for DENV; and (iii) potential strategies to overcome these challenges. This article forms part of a symposium on flavivirus drug discovery in Antiviral Research.

Item Type: Article
Keywords: Nucleoside inhibitor Dengue Prodrug
Date Deposited: 29 Apr 2016 23:45
Last Modified: 29 Apr 2016 23:45
URI: https://oak.novartis.com/id/eprint/25493

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