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Number of items: 319.


Acharya, Nandini and Sabatos-Peyton, Catherine and Anderson, Ana (2020) Tim-3 finds its place in the cancer immunotherapy landscape. Journal for ImmunoTherapy of Cancer, 8 (1). ISSN 20511426

Adler, Rick and Clark, Elizabeth and Cline, Mark and Connor, Michael and Crabbs, Torrie and Fossey, Stacey and Malarkey, David and Tornquiest, Susan and Vernau, William (2020) Mission Accomplished: The ACVP/STP Coalition for Veterinary Pathology Fellows Completes Its Objectives, but Its Legacy and Spirit Live On. Toxicologic pathology. pp. 1-7.

Akinjiyan, Favour and Fazal, Aleem and Hild, Marc and Beckwith, Rohan and Paulk, Josh and Carbonneau, Seth (2020) A novel luminescence-based high-throughput approach for cellular resolution of protein ubiquitination using tandem ubiquitin binding entities (TUBEs). SLAS DISCOVERY: Advancing the Science of Drug Discovery, 25 (4). pp. 350-360. ISSN 2472-55522472-5560

Algarín, Esperanza and Díaz-Tejedor, Andrea and Mogollón, Pedro and Hernández-García, Susana and Corchete, Luis A and San-Segundo, Laura and Martín-Sánchez, Montserrat and González-Méndez, Lorena and Schoumacher, Marie and Banquet, Sébastien and Kraus-Berthier, Laurence and Kloos, Ioana and Halilovic, Ensar and Maacke, Heiko and Gutiérrez, Norma C and Mateos, María-Victoria and Paíno, Teresa and Garayoa, Mercedes and Ocio, Enrique M (2020) PRECLINICAL EVALUATION OF THE SIMULTANEOUS INHIBITION OF MCL-1 AND BCL-2 WITH THE COMBINATION OF S63845 AND VENETOCLAX IN MULTIPLE MYELOMA. Haematologica : the hematology journal, 105. ISSN 1592-8721

Alper, Phillip and Deane, Jonathan and Betschart, Claudia and Buffet, David and Collignon Zipfel, Geraldine and Gordon, William and Hampton, Janice and Hawtin, Stuart and Ibanez, Maureen and Jiang, Tao and Junt, Tobias and Knoepfel, Thomas and Liu, Bo and Maginnis, Jillian and Mckeever, Una and Michellys, Pierre and Mutnick, Daniel and Nayak, Bishnu and Niwa, Satoru and Richmond, Wendy and Rush, James and Syka, Peter and Zhang, Yi and Zhu, Xuefeng (2020) Discovery of potent, orally bioavailable in vivo efficacious antagonists of the TLR7/8 pathway. Bioorganic and Medicinal Chemistry Letters, 30 (17). p. 127366. ISSN 14643405

Ambrozic, Rok and Arzensek, Dejan and Podgornik, Ales (2020) Designing scalable ultrafiltration/diafiltration process of monoclonal antibodies via mathematical modeling by coupling mass balances and Poisson–Boltzmann equation. Biotechnology and Bioengineering. ISSN 0006-35921097-0290

Angst, Daniela and Gessier, Francois and Janser, Philipp and Pulz, Robert and Vulpetti, Anna and Waelchli, Rudolf and Beerli, Christian and Littlewood-Evans, Amanda and Dawson King, Janet and Nuesslein-Hildesheim, Barbara and Wieczorek, Grazyna and Gutmann, Sascha and Scheufler, Clemens and Hinniger, Alexandra and Zimmerlin, Alfred Gilbert and Funhoff, Enrico and Cenni, Bruno (2020) Discovery of LOU064 (Remibrutinib), a Potent and Highly Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase. Journal of Medicinal Chemistry. ISSN 0022-26231520-4804

Arat, Seda and Ietswaart, Robert and Chen, Amanda and Farahmand, Saman and Kim, Bunjum and Armstrong, Duncan and Urban, Laszlo and DuMouchel, William and Jeffrey, Sutherland and Fekete, Alexander (2020) Machine learning guided association of adverse drug reactions with in vitro target-based pharmacology. EBioMedicine., 57. pp. 1028-1037. ISSN eBioMedicine

Arbues, Ainhoa and Brees, Dominique and Chibout, Salah-Dine and Fox, Todd and Kammueller, Michael and Portevin , Damien (2020) TNF-α antagonists differentially induce TGF-β1-dependent resuscitation of dormant-like Mycobacterium tuberculosis. PLoS pathogens, 16 (2). e1008312. ISSN 1553-7374

Arbues, Ainhoa and Kammueller, Michael and Portevin, Damien (2020) Generating three-dimensional human granulomas in vitro to study Mycobacterium tuberculosis-host interaction. BIO-PROTOCOL, 10 (22). ISSN 2331-8325

Arora, Rishi and Liew, Chong Wai and Soh, Tingjin Sherryl and Otoo, Dorcas and Seh, Cheah Chen and Yue, Qing and Nilar, Shahul Hameed and Wang, Gang and Yokokawa, Fumiaki and Noble, Christian Guy and Chen, Yen-Liang and Shi, Pei-Yong and Lescar, Julien and Smith, Thomas and Benson, Timothy and Lim, Siew Pheng (2020) Two RNA tunnel inhibitors bind in highly conserved sites in Dengue virus NS5 polymerase: structural and functional studies. Journal of virology.

Auberson, Yves (2020) EFMC, medicinal chemistry and chemical biology in Europe. ChemMedChem : chemistry enabling drug discovery, 15.

Auld, Douglas (2020) Microplate Selection and Recommended Practices in High-throughput Screening and Quantitative Biology. Jun 2020.

Auld, Douglas and Busby, Scott and Smith, Thomas and Renaud, Nicole and Carbonneau, Seth and Numao, Shin and Concannon, John and Dumelin, Christoph (2020) Advancements in assay technologies and strategies to enable drug discovery. ACS Chemical Biology. ISSN 1554-89291554-8937

Auld, Douglas and Casalena, Dominick and Wright, Kirk (2020) Multimodal small-molecule screening for human prion protein binders. Journal of Biological Chemistry, 295 (39). ISSN 0021-92581083-351X

Auld, Douglas and Jenkins, Jeremy and Concannon, John (2020) Cell size homeostasis is maintained by a circuitry involving a CDK4-determined target size that programs the cell size-dependent activation of p38. bioRxiv.


Baenziger, Markus and Langlois, Audrey and Gschwend, Bjoern and Wickendick, Regina and Baierl, Marcel and Kovacic, Nikola and Haller, Michael and Schuerch, Friedrich and Shen, Xiaodong and Fu, Peng and Lianhe , Coauthor and Eswaran, Sumesh and Devanathan, Krishnaswamy (2020) Synthesis Development of the selective estrogen receptor degrader (SERD) LSZ102. Organic Process Research & Development, 24 (8). pp. 1405-1419. ISSN 1083-61601520-586X

Balakrishnan, Anand and Hekmat-Nejad, Mohammad and Price, Edmund and Cantwell, John and Wartchow, Charles and Shaul, Jacob and Luu, Catherine and Spraggon, Glen and DiDonato, Michael and Vo, Michael (2020) Biochemical characterization of respiratory syncytial virus RNA dependent RNA polymerase complex. ACS infectious diseases, 6 (10). pp. 2800-2811. ISSN 2373-8227

Ballerini, Andrea and Chua, Corrine and Rhudy, Jessica and Susnjar, Antonia and Trani, Nicola and Jain, Priya and Laue, Grit and Lubicka, Danuta and Shirazi-Fard, Yasaman and Ferrari, Mauro and Stodieck, Louis and Cadena, Samuel and Grattoni, Alessandro (2020) Muscle Atrophy: Counteracting Muscle Atrophy on Earth and in Space via Nanofluidics Delivery of Formoterol. Advanced Therapeutics, 3 (7). ISSN 23663987

Baran, Szczepan and Das Gupta, Ayan and Mathur, Ashwini and Rowlands, David and Walker, Dana and Lim, Maria and Schaevitz, Laura and Shanmukhappa, Kumar (2020) Continuous, Automated Breathing Rate and Body Motion Monitoring of Rats With Paraquat-Induced Progressive Lung Injury. Frontiers in Physiology, 11. ISSN 1664042X

Barkley, Deborah and Hatsis, Panagiotis and Glick, Jim and Li, Wenkui and Flarakos, Jimmy (2020) Dixon's Q-test and Student's t-test to assess analog internal standard response in nonregulated LC-MS/MS bioanalysis. Bioanalysis, 12 (21). pp. 1535-1543. ISSN 17576199

Bačnik, Katarina and Kutnjak, Denis and Jerič Kokelj, Barbara and Tuta, Nika and Lončar, Tan and Vogelsang, Matjaz and Ravnikar, Maja (2020) Metagenomic characterization of parental and production CHO cell lines for detection of adventitious viruses. Biologicals. ISSN 10958320

Beckmann, Nicolau (2020) Editorial for “Echo Time-Dependence of Observed Lung T1 in Patients With Cystic Fibrosis and Correlation With Clinical Metrics”. Journal of Magnetic Resonance Imaging, 52 (6). pp. 1655-1656. ISSN 15222586

Beckmann, Nicolau (2020) Editorial on “Validation of Automated Perfusion-Weighted Phase-Resolved Functional Lung (PREFUL)-MRI in Patients With Pulmonary Diseases”. Journal of magnetic resonance imaging, 52 (1). pp. 115-116.

Beckmann, Nicolau (2020) Non-Invasive Preclinical Lung Imaging: A Pharmaceutical Perspective. Bruker White Paper.

Bednarczyk, Dallas and Sanghvi, Menaka (2020) Organic anion transporting polypeptide 2B1 (OATP2B1), an expanded substrate profile, does it align with OATP2B1's hypothesized function? Xenobiotica.

Bergboer, Judith GM and Kelder, Martijn JE and van Min, Max and Tuta, Nika and Crček, Mitja and Vogelsang, Matjaz (2020) Targeted Locus Amplification and NGS combined with qPCR-based breakpoint analysis for the assurance of monoclonality in recombinant cell lines. as white paper on Cergentis webpage.

Bhatt, Shruti and Pioso, Marissa and Olesinski, Elyse and Yilma, Binyam and Leutz, Buon and Adamia, Sophia and Zhu, Holly and Yanan, Kuang and Mogili, Abhishek and Ryan, Jeremy and Wang, Youzhen and Morris, Erick and Halilovic, Ensar and Paweletz, Cloud P. and Weinstock, David M. and Garcia, Jacqueline S. and Letai, Anthony (2020) Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia. Cancer Cell, 38 (6). 872-890.e6. ISSN 18783686

Blanco, Maria-Jesus (2020) New Chemical Modalities and Strategic Thinking in Early Drug Discovery. ACS medicinal chemistry letters, 11 (3). pp. 228-231. ISSN 1948-5875

Blank, Jutta and Hintermann, Samuel and Schneider, Nadine and Schuffenhauer, Ansgar and Shultz, Michael (2020) Outline for a Perspective Article on Novartis’ approach to compound screening for hit and lead finding and the design of compounds sets for diversity driven screening. Journal of medicinal chemistry for publisher only.

Blümel, Oliver and Buecheler, Jakob and Rodrigues, Miguel and Garaldes, Vitor and Hoelzl, Georg and Bechtold-Peters, Karoline and Friess, Wolfgang (2020) Cryoconcentration and 3D Temperature Profiles during Freezing of mAb Solutions in Large-Scale PET Bottles and a Novel Scale-Down Device. Pharmaceutical Research, Formul. ISSN 0724-8741

Bogdanffy, Matthew S and Lesniak, Jacob and Mangipudy, Raja and Stanley, Ann Marie and Colman, Karyn and Blanset, Diann (2020) Tg.rasH2 mouse model for Assessing Carcinogenic Potential of Pharmaceuticals: Industry Survey and Recommendations. International Journal of Toxicology. ISSN 1091-58181092-874X

Bogdanffy, Matthew S and Lesniak, Jacob and Mangipudy, Raja and Stanley, Ann Marie and Colman, Karyn and Blanset, Diann and Sistare, Frank D and Garcia-Tapia, David and Monticello, Thomas (2020) Tg.rasH2 Mouse Model for Assessing Carcinogenic Potential of Pharmaceuticals: Industry Survey of Current Practices. International journal of toxicology. ISSN 1092874X

Boike, Lydia and Cioffi, Alexander and Majewski, Felix C. and Co, Jennifer and Henning, Nathaniel J. and Jones, Michael and Liu, Gang and McKenna, Jeffrey and Tallarico, John and Schirle, Markus and Nomura, Daniel K. (2020) Discovery of a Covalent Ligand Targeting an Intrinsically Disordered Cysteine Within MYC. Cell chemical biology. ISSN 2451-9448

Bolon, Brad and Caverly Rae, Jessica and Colman, Karyn and Francke, Sabine and Jensen, Karl and Keane, Kevin and McInnes, Elizabeth F. and Nakano-Ito, Kyoko and Perry, Rick and Polack, Evelyne and Reagan, Karen S. and Romeike, Annette and Young, Jamie K. and Galbreath, Elizabeth (2020) Toxicologic Pathology Forum Opinion Piece: Current Use of Non-blinded vs. Blinded Histopathologic Evaluation in Animal Toxicity Studies. Experimental and Toxicologic Pathology. ISSN 0192-62331533-1601

Bova, Kaitlin (2020) Mitigating Medication Errors in Clinical Research. Clinical Trial Supply Handbook - Summer Edition .

Braun, Marie-Gabrielle and Díaz-Rodríguez , Alba and Louis, Diorazio and Kenneth, Fraunhoffer and John, Hayler and Matthew, Hickey and Jonathan , Latham and Lovelle, Lucie and Mark, McLaws and Andrew, Parsons and Paul, Richardson and Alan, Steven and Jack, Terrett and Timothy, White and Jingjun, Yin (2020) Green Chemistry Articles of Interest to the Pharmaceutical Industry. Organic Process Research & Development. ISSN 1083-61601520-586X

Brovč, Ema Valentina and Mravljak, Janez and Pajk, Stane and Sink, Roman (2020) Degradation of polysorbates 20 and 80 catalysed by histidine chloride buffer. European journal of pharmaceutics and biopharmaceutics, 154. pp. 236-245. ISSN 09396411

Brovč, Ema Valentina and Mravljak, Janez and Pajk, Stane and Sink, Roman (2020) Rational design to biologics development: The polysorbates point of view. International Journal of Pharmaceutics, 581. ISSN 18733476

Bruin, Gerardus and Hockey, Hans-Ulrich and Patekar, Manmath and Charef, Pascal and Woessner, Ralph and Boutouyrie-Dumont, Bruno and Fu, Rong and Philip, La Stella and Bardur, Sigurgeirsson (2020) Comparison of pharmacokinetics, safety and tolerability of secukinumab administered subcutaneously using different 2 mL delivery systems in healthy volunteers and in psoriasis patients. British journal of clinical pharmacology. pp. 1-14.

Bucher, Christoph and Linden, Anthony and Heimgartner, Heinz (2020) Synthesis and Solid State Conformation of Tetrapeptide Amides Containing two Aib and two (Me)Phe Residues – Use of Enantiomerically Pure 2-Benzyl-2-methyl-2H-azirin-3-amines as (Me)Phe-Synthons. Chemistry & Biodiversity. ISSN 1612-18721612-1880


Cabanski, Maciej and Teri, Oldaker and Jennifer , Stewart and Nithianandan, Selliah and Steve, Eck and Cherie, Green and Virginia, Litwin and Vitaliti Garami, Alessandra (2020) Flow cytometric method transfer: Recommendations for best practice. Cytometry Part B: Clinical Cytometry, 100 (1). pp. 52-62. ISSN 1552-49491552-4957

Cadena, Samuel (2020) Contrasting atrophy in space and on Earth. Genes in Space: Research Brief.

Caduff, Nicole and McHugh, Donal and Murer, Anita and Rämer, Patrick and Raykova, Ana and Landtwing, Vanessa and Rieble, Lisa and Keller, Christian and Prummer, Michael and Hoffmann, Laurent and Lam, Janice and Chiang, Alan and Raulf, Friedrich and Azzi, Tarik and Berger, Christoph and Rubic-Schneider, Tina and Traggiai, Elisabetta and Lünemann, Jan and Kammueller, Michael and Münz, Christian (2020) Immunosuppressive FK506 treatment leads to more frequent EBV-associated lymphoproliferative disease in humanized mice. PLoS pathogens, 16 (4). pp. 1-25. ISSN 15537374

Cain, Meredith and Vemula, Janardhana Rao and Zollinger, Markus and Umehara, Ken-Ichi and Elbast, Walid and Erpenbeck, Veit (2020) A study of the effect of cyclosporine on fevipiprant pharmacokinetics and its absolute bioavailability using an intravenous microdose approach. Drug Metabolism and Disposition, 48 (10). pp. 917-924. ISSN 1521009X

Camilleri, Michael and Linker Nord, Sara and Burton, Duane and Oduyebo, Ibironke and Zhang, Yiming and Chen, Jin and Im, Koeun and Bhad, Prafulla and Badman, Michael and Sanders, David and Walters, Julian (2020) A Randomized Controlled Trial of a Farnesoid X Receptor Agonist, Tropifexor, in Patients with Primary Bile Acid Diarrhea. Alimentary pharmacology & therapeutics, 52 (5). pp. 808-820. ISSN 02692813

Canham, Steve and Jenkins, Jeremy and Auld, Douglas (2020) Systematic Chemogenetic Library Assembly. BioRxiv.

Capaldi, Daniel and Akhtar, Nadim and Atherton, Tom and Benstead, David and Charaf, Ayman and De Vijlder, Thomas and Heatherington, Carl and Hoernschemeyer, Joerg and Jiang, Hong and Rieder, Ulrike and Ring, Francis and Peter, Robert and Stolee, Jessica and Wechselberger, Rainer (2020) Strategies for Identity Testing of Therapeutic Oligonucleotide Drug Substances and Drug Products. Nucleic Acid Therapeutics (00). ISSN 2159-33372159-3345

Capdevila, Jaume and Wirth, Lori J and Ernst, Thomas and Ponce Aix, Santiago and Lin, Chia-Chi and Ramlau, Rodryg and Butler, Marcus O and Delord, Jean-Pierre and Fuhrer, Dagmar and Hutter-Kronke, Marie-Luise and Forde, Patrick M and Wrona, Anna and Santoro, Armando and Sadow, Peter M and Szpakowski, Sebastian and Wu, Hongqian and Bostel, Geraldine and Faris, Jason and Cameron, Scott and Varga, Andreea and Taylor, Matthew and Arkoski, Peter (2020) PD-1 Blockade in Anaplastic Thyroid Carcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. pp. 1-9. ISSN 15277755

Carballido, Jose and Regairaz Kalenga Kapiamba, Camille and Rauld, Celine and Raad, Layla and Picard, Damien and Kammueller, Michael (2020) The emerging jamboree of transformative therapies for autoimmune diseases. Frontiers in Immunology.

Carey, Kimberly and Paulus, Geraldine and Wang, Lingfei and Balce, Dale and Bergman, Phil and Ferder, Ianina and Kong, Lingjia and Renaud, Nicole and Singh, Shantanu and Karhohs, Kyle and Carpenter, Anne and Kost-Alimova, Maria and Nyfeler, Beat and Lassen, Kara and Virgin, Herbert and Xavier, Ramnik (2020) TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41. Cell Reports, 33 (6). ISSN 22111247

Chacón Simon, Selena and Wang, Feng and Thomas, Lance R and Phan, Jason and Zhao, Bin and Olejniczak, Edward T and Macdonald, Jonathan D and Shaw, J Grace and Schlund, Caden and Payne, William and Creighton, Joy and Stauffer, Shaun R and Waterson, Alex G and Tansey, William P and Fesik, Stephen W (2020) Discovery of WD Repeat-Containing Protein 5 (WDR5)-MYC Inhibitors Using Fragment-Based Methods and Structure-Based Design. Journal of medicinal chemistry, 63 (8). pp. 4315-4333. ISSN 1520-4804

Chawla, Shikha and Berkelar, Majoska and Dasen, Boris and Halleux, Christine and Kramer, Ina and Guth-Gundel, Sabine and Ghosh, Sourab and Martin, Ivan and Barbero, Andrea and Occhetta, Paola (2020) Blockage of bone morphogenetic protein signalling counteracts hypertrophy in a human osteoarthritic micro-cartilage model. Journal of cell science, 133 (23). ISSN 14779137

Chen, Gregory and Grauzinyte, Migle and van der Vaart, Aad and Boll, Bjoern (2020) Applying Pattern Recognition as a Robust Approach for Silicone Oil Droplet Identification in Flow-Microscopy Images of Protein Formulations. Journal of pharmaceutical sciences. ISSN 00223549

Chen, Hui and Sun, Shuhao and Liu, Yahu and Liao, Xuebin (2020) Nickel-Catalyzed Cyanation of Aryl Halides and Hydrocyanation of Alkynes via C-CN Bond Cleavage and Cyano Transfer. ACS Catalysis, 10. pp. 1397-1405. ISSN 2155-54352155-5435

Chianelli, Donatella and Rucker, Paul and Tully, David and Nelson, John and Liu, Xiaodong and Bursulaya, Badry and Hernandez, Eloy and Chu, Alan and Schmeits, James and Hill, Robert and Bao, Dingjiu and Zoll, Jocelyn and Kim, Young and Groessl, Todd and McNamara, Peter and Richmond, Wendy and Sancho Martinez, Ignacio and Badman, Michael and Molteni, Valentina and Jason, Roland and Jane, Wu and David, Huang and Bo, Liu and Andrew, Phimister and Martin, Seidel and Sean, Joseph and Bryan, Laffitte (2020) Nidufexor (LMB763), a Novel FXR Modulator for the Treatment of Nonalcoholic Steatohepatitis (NASH). Journal of medicinal chemistry, 63 (8). pp. 3868-3880. ISSN 9b01621

Chianelli, Donatella and Rucker, Paul and Tully, David and Nelson, John and Liu, Xiaodong and Bursulaya, Badry and Hernandez, Eloy and Chu, Alan and Schmeits, James and Hill, Robert and Bao, Dingjiu and Zoll, Jocelyn and Kim, Young and Groessl, Todd and McNamara, Peter and Richmond, Wendy and Sancho Martinez, Ignacio and Badman, Michael and Molteni, Valentina and Jason, Roland and Jane, Wu and David, Huang and Bo, Liu and Andrew, Phimister and Martin, Seidel and Sean, Joseph and Bryan, Laffitte and Prashad, Mahavir and Schlama, Thierry and Liu, Yugang (2020) Nidufexor (LMB763), a Novel FXR Modulator for the Treatment of Nonalcoholic Steatohepatitis. Journal of medicinal chemistry, 63 (8). pp. 3868-3880. ISSN 9b01621

Clarke, Adrian and ehkirch, anthony (2020) The Current Status and Future of Two- and Multidimensional Liquid Chromatography in Pharmaceutical R&D and QC. LC-GC Europe : Solutions for Separation Scientists., 33 (3). pp. 136-150. ISSN 1471-6571

Cowan, Cameron and Renner, Magdalena and De Gennaro, Martina and Gross-Scherf, Brigitte and Goldblum, David and Hou, Yanyan and Munz, Martin and Rodrigues, Tiago M. and Krol, Jacek and Szikra, Tamas and Cuttat-Theurillat, Rachel and Waldt, Annick and Papasaikas, Panagiotis and Diggelmann, Roland and Patino-Alvarez, Claudia P. and Galliker, Patricia and Spirig, Stefan and Pavlinic, Dinko and Gerber-Hollbach, Nadine and Schuierer, Sven and Srdanovic, Aldin and Balogh, Marton and Panero, Riccardo and Kusnyerik, Akos and Szabo, Arnold and Stadler, Michael and Orgül, Selim and Picelli, Simone and Hasler, Pascal W. and Hierlemann, Andreas and Scholl, Hendrik P. N. and Roma, Guglielmo and Nigsch, Florian and Roska, Botond (2020) Cell types of the human retina and its organoids at single-cell resolution: developmental convergence, transcriptomic identity, and disease map. Cell, 182 (6). p. 1623. ISSN 00928674

Czyz, Stefan and Wewers, Martin and Finke, Jan and Kwade, Arno and Van Eerdenbrugh, Bernard and Juhnke, Michael and Bunjes, Heike (2020) Spray 1 drying of API nanosuspensions: Importance of particle size, matrix former content and drying temperature for successful formulation and process development. European journal of pharmaceutics and biopharmaceutics, 152 (July). pp. 63-71. ISSN 1873-3441; 0939-6411

chaudhury, anwesha and Zhu, Xu and Chu, Lulu and Goliaei, Ardeshir and Kearns, Jeff and Stein, Andrew (2020) Chimeric Antigen Receptor T Cell Therapies: A Review of Cellular Kinetic-Pharmacodynamic Modeling Approaches. Journal of Clinical Pharmacology, 60 (S1). S147-S159. ISSN 15524604


DaSilva, Jamie K. and Breidenbach, Laura and Deats, Tracy and Li, Dingzhou and Treinen, Kimberly and Dinklo, Theo and Kervyn, Sophie and Teuns, Greet and Traebert, Martin and Hempel, Katja (2020) Nonclinical species sensitivity to convulsions: An IQ DruSafe consortium working group initiative. Journal of Pharmacological and Toxicological Methods, 103. ISSN 1873488X

Dalvit, Claudio and Veronesi, Marina and Vulpetti, Anna (2020) Fluorine NMR functional screening: from purified enzymes to human intact living cells. Journal of Biomolecular NMR. ISSN 15735001

Delord, Jean-Pierre and Argilés, Guillem and Fayette, Jerôme and Wirth, Lori and Kasper, Stefan and Siena, Salvatore and Mesia, Ricard and Berardi, Rossana and Cervantes, Andrés and Dekervel, Jeroen and Zhao, Sylvia and Sun, Yongjian and Hao, Lu and Tiedt, Ralph and Vicente Gabarda, Sergio and Myers, Andrea and Siu, Lillian L (2020) A phase 1b study of the MET inhibitor capmatinib combined with cetuximab in patients with MET-positive colorectal cancer who had progressed following anti-EGFR monoclonal antibody treatment. Investigational New Drugs. ISSN 15730646

Di Marco, Giulia and Vallese, Francesca and Jourde, Benjamin and Bergsdorf, Christian and Sturlese, Mattia and De Mario , Agnese and Techer-Etienne, Valerie and Haasen, Dorothea and Oberhauser, Berndt and Schleeger, Simone and Minetti, Giulia and Moro, Stefano and Rizzuto, Rosario and De Stefani, Diego and Fornaro, Mara and Mammucari, Cristina (2020) A high throughput screening identifies MICU1 targeting compounds. Cell Reports, 30. pp. 1-11.

Diagana, Thierry and Gupta, Devendra and Voorberg-van der Wel, Annemarie and Zeeman, Anne-Marie and Nieuwenhuis, Ivonne G and van der Werff, Nicole M. and Klooster, Els J and Klop, Onny and Vermaat, Lars C and Kocken, Clemens and Dembele, Laurent (2020) A dual fluorescent Plasmodium cynomolgi reporter line reveals in vitro malaria hypnozoite reactivation. Communications biology, 3 (1). ISSN 23993642

Diekhoff, Torsten and Fischer, Thomas and Schefer, Quirino and Dörner, Thomas and Posch, Maximilian Georg and Laurent, Didier and Li, Yue and Wagner, Frank and Oliver, Stephen (2020) Ianalumab (VAY736) in primary Sjögren’s syndrome: assessing disease activity using multi-modal ultrasound. Clinical and Experimental Rheumatology.

Dittrich, Birger and Chan, Stephen and Wiggin, Seth and Stevens, Joanna S. and Pidcock, Elna (2020) Fast energy minimization of the CCDC drug subset structures by molecule-in-cluster computations allows independent structure validation and model completion. CrystEngComm. ISSN 1466-8033

Dittrich, Birger and Sever, Christoph A. and Luebben, Jens (2020) Disappearing disorder. CrystEngComm. ISSN 1466-8033

Do Valle Duraes, Fernanda and Lafont, Armelle and Darribat, Katy and Cuttat-Theurillat, Rachel and Waldt, Annick and Naumann, Ulrike and Wieczorek, Grazyna and Gaulis, Swann and Pfister, Sabina and Beibel, Martin and Li, Jianping and Roma, Guglielmo and Warncke, Max (2020) Immune cell landscaping reveals a protective role for Tregs during kidney injury and fibrosis. "Immune cell landscaping reveals a protective role for regulatory T cells during kidney injury and fibrosis, 5 (3).

Do Valle Duraes, Fernanda and Lafont, Armelle and Darribat, Katy and Martin, Kea and Cuttat-Theurillat, Rachel and Waldt, Annick and Naumann, Ulrike and Wieczorek, Grazyna and Gaulis, Swann and Pfister, Sabina and Beibel, Martin and Li, Jianping and Roma, Guglielmo and Warncke, Max and Mertz, Kirsten (2020) Immune cell landscaping reveals a protective role for regulatory T cells during kidney injury and fibrosis. JCI insight, 5 (3). ISSN 23793708

Dolman, Andrew and Yu, Helen and Gusev, Arkady (2020) Data driven CRO benchmarking for biomarker analysis. Bioanalysis, 12 (16). pp. 1117-1127. ISSN 1757-6180

Doo, David W and Meza-Perez, Selene and Londoño, Angelina I and Goldsberry, Whitney N and Katre, Ashwini A. and Boone, Jonathan D and Moore, Dylana J. and Hudson, Cindy T and Betella, Ilaria and McCaw, Tyler R and Gangrade, Abhishek and Bao, Riyue and Luke, Jason J and Yang, Eddy S and Birrer, Michael J. and Starenki, Dmytro and Cooper, Sara J and Buchsbaum, Donald J and Norian, Lyse A and Randall, Troy D and Arend, Rebecca C (2020) Inhibition of the Wnt/β-catenin pathway enhances anti-tumor immunity in ovarian cancer. Therapeutic Advances in Medical Oncology, 12. pp. 1-16. ISSN 1758-835920913798

Dummer, Reinhard and Brase, Jan Christoph and Garrett, James and Campbell, Katie and Gasal, Eduard and Squires, Matthew and Gusenleitner, Daniel and Santinami, Mario and Atkinson, Victoria and Mandala, Mario and Chiarion-Sileni, Vanna and Flaherty, Keith and Larkin, James and Robert, Caroline and Kefford, Richard and Kirkwood, John and Hauschild, Axel and Schadendorf, Dirk and Long, Georgina (2020) Adjuvant dabrafenib plus trametinib versus placebo in patients with resected, BRAFV600-mutant, stage III melanoma (COMBI-AD): exploratory biomarker analyses from a randomised, phase 3 trial. The Lancet Oncology, 21 (3). pp. 358-372.

Dummer, Reinhard and Lebbé, Celeste and Atkinson, Victoria and Mandalà, Mario and Nathan, Paul and Arance, Ana and Richtig, Erika and Yamazaki, Naoya and Robert, Caroline and Schadendorf, Dirk and Tawbi, Hussein A. and Ascierto, Paolo A. and Ribas, Antoni and Flaherty, Keith and Pakhle, Neha and Campbell, Katie and Gusenleitner, Daniel and Masood, Aisha and Brase, Jan Christoph and Gasal, Eduard and Long, Georgina V. (2020) Spartalizumab in Combination With Dabrafenib And Trametinib in Advanced BRAF V600–Mutant Melanoma: Efficacy, Safety, and Biomarker Findings in Parts 1 and 2 of COMBI-i. Nature medicine, 26 (9).

Dumouchel, Jennifer and Argikar, Upendra and Adams, Christopher and Prasanna, Ganesh and Ehara, Takeru and Kim, Sunkyu and Breen, Chris and Mogi, Muneto (2020) Understanding metabolism related differences in ocular efficacy of MGV354. Xenobiotica. pp. 1-10. ISSN 13665928


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Gallou, Fabrice (2020) N2Phos. An easily made, highly effective ligand designed for ppm level Pd-catalyzed Suzuki-Miyaura cross couplings in water. Chemical science, 11. pp. 5205-5212.

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Grande, Enrique and Giovannini, Monica and Marriere, Eddie and Pultar, Philippe and Quinlan, Michelle and Chen, Heller and Curigliano, Giuseppe and Cui, Xiaoming (2020) Effect of capmatinib on the pharmacokinetics of digoxin and rosuvastatin administered as a two-drug cocktail in patients with MET-dysregulated advanced solid tumors: A phase I, multicenter, open-label, single-sequence drug-drug interaction study. British Journal of Clinical Pharmacology.

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Kawanami, Toshio and La Bonte, Laura and Amin, Jakal and Thibodeaux, Stefan and Lee, Cameron and Argintaru, Andreea and Adams, Christopher (2020) A novel diclofenac-hydrogel conjugate system for intraarticular sustained release: Development of 2-pyridylamino-substituted 1-phenylethanol (PAPE) and its derivatives as tunable traceless linkers. International journal of pharmaceutics, 585. p. 119519. ISSN 03785173

Kennedy, Ryan and Yung, Christina and Luzzi Castro, Nazarena (2020) How design systems help teams build faster and create better experiences for users. PISTOIA Alliance Blog.

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Knoepfel, Thomas and Nimsgern, Pierre and Jacquier, Sebastien and Bourrel, Marjorie and Vangrevelinghe, Eric and Glatthar, Ralf and Behnke, Dirk and Alper, Phillip and Michellys, Pierre and Deane, Jonathan and Junt, Tobias and Collignon Zipfel, Geraldine and Limonta, Sarah and Hawtin, Stuart and Andre, Cedric Bernard and Boulay, Thomas and Loetscher, Pius and Faller, Michael and Blank, Jutta and Feifel, Roland and Betschart, Claudia (2020) Target-Based Identification and Optimization of 5-Indazol-5-yl Pyridones as Toll-like Receptor 7 and 8 Antagonists using a Biochemical TLR8 Antagonist Competition Assay. Journal of Medicinal Chemistry. ISSN 0022-26231520-4804

Kohlberger, Michael and Wildner, Sabrina and Regl, Christof and Huber, Christian G. and Gadermaier, Gabriele (2020) Rituximab-specific DNA aptamers are able to selectively recognize heat-treated antibodies. PLoS ONE, 15 (11 Nov). ISSN 19326203

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Kramlinger, Valerie and Argikar, Upendra and Khojasteh, Cyrus and Driscoll, James and Heck, Carley and Llyod, King and Jackson, Klarissa and Jian, Wenying and Kalgutkar, Amit and Miller, Grover and Rietjens, Ivonne and Teitelbaum, Aaron and Wang, Kai and Wei, Cong (2020) Novel advances in biotransformation and bioactivation research—2019 year in review*. Drug Metabolism Reviews. pp. 1-33. ISSN 10979883

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Krewson, Elizabeth A. and Sanderlin, Edward J. and Marie, Mona and Velcicky, Juraj and Loetscher, Pius and Yang, Li V. (2020) The proton-sensing GPR4 receptor regulates paracellular gap formation and permeability of vascular endothelial cells. iScience, 23 (2). ISSN 25890042

Kublin, James G. and Murphy, Sean C. and Maenza, Janine and Seilie, Annette M. and Jain, Jay Prakash and Goswami, Budhaditya and Berger, David and Spera, Danielle and Stein, Daniel S. and Zhao, Rong and Pertel, Peter and Prince, William (2020) Causal prophylactic efficacy of ganaplacide (KAF156) in a controlled human malaria infection model. Clinical Infectious Diseases, Clin I. ISSN 1058-48381537-6591


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Leemans Martin, Laura and Peschke, Theo and Venturoni, Francesco and Mostarda, Serena (2020) Pharmaceutical industry perspectives on flow chemocatalysis and biocatalysis. Current Opinion in Green and Sustainable Chemistry, 25. ISSN 24522236

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Li, Lujin and Ding, Junjie (2020) General considerations of model-based meta-analysis. Chinese Journal of Clinical Pharmacology and Therapeutics, 25 (11). pp. 1250-1267. ISSN 10092501

Lim, Yun-Sung and You, Byung Hoon and Kim, Hee-Bok and Lim, So Hyun and Song, Jae Geun and Bae, Min Goo and Han, Hyo-Kyung and Choi, Young Hee and Choi, Han Seok (2020) A New Therapeutic Approach Using a Calcilytic (AXT914) for Postsurgical Hypoparathyroidism in Female Rats. Endocrinology, 161. ISSN 1945-7170

Lima, Fabio and Andre, Jerome and Marziale, Alexander and Greb, Andreas and Glowienke, Susanne and Meisenbach, Mark and Schenkel, Berthold and Martin, Benjamin and Sedelmeier, Joerg Mathias (2020) Continuous Flow as Enabling Technology: Synthesis of Heteroaromatic Sulfinates as Bench Stable Cross-Coupling Partners. Organic Letters. ISSN 1523-70601523-7052

Lin, Fallon and Stockwell, Brent and deCarvalho, Ana and Ye, Ling and Yang, Guizhi and Pagliarini, Raymond and Malesky, Kimberly and Gao, Hui and Korn, Joshua (2020) Patient-derived glioblastoma cultures as a tool for small-molecule drug discovery. Oncotarget, 11 (4). pp. 443-451. ISSN 1949-2553

Lingel, Andreas and Vulpetti, Anna and Reinsperger, Tony and Proudfoot, Andrew and Denay, Regis and Frommlet, Alexandra and Gossert, Alvar and Henry, Christelle and Hommel, Ulrich and Luy, Burkhard and Frank, Andreas (2020) Comprehensive and High-Throughput Exploration of Chemical Space Using Broadband 19F NMR Based Screening. Angewandte Chemie International Edition. ISSN 1433-78511521-3773

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Liu, MM and Fields, FO and Prescott, JS and Bello, A and Bower, N and Hartke, J and Kadambi, V and Lapadula, Daniel and Stoch, A and Derzi, M (2020) Evaluation of Therapeutics for Severely Debilitating or Life-Threatening Diseases or Conditions: Defining Scope to Enable Global Guidance Development. Clinical Pharmacology and Therapeutics, 107 (3). pp. 514-520. ISSN 15326535

Liu, Yahu and Chen, Hui and Liao, Xuebin (2020) Recent Progress in Radical Decarboxylative Functionalizations Enabled by Transition-Metal (Ni, Cu, Fe, Co or Cr) Catalysis. Synthesis (Germany), 53 (1). pp. 1-29. ISSN 1437210X

Liu, Yahu and Jin, Qihui and Ding, Qiang and Hao, Xueshi and Mo, Tingting and Yan, Shanshan and Zou, Yefen and Huang, Zhihong and Zhang, Xiaoyue and Gao, Wenqi and Wu, Tom Y.-H. and Li, Chun and Bursulaya, Badry and DiDonato, Michael and Zhang, You-Qing and Deaton, Lisa and Shen, Weijun and Taylor, Brandon and Kamireddy, Anwesh and Harb, George and Li, Jing and Jia, Yong and Schumacher, Andrew and Laffitte, Bryan and Glynne, Richard and Pan, Shifeng and McNamara, Peter and Molteni, Valentina and Loren, Jon (2020) A Dual Inhibitor of DYRK1A and GSK3β for β-Cell Proliferation: Aminopyrazine Derivative GNF4877. ChemMedChem, 15. ISSN 18607187

Liu, Yahu and Zou, Yefen and Yan, Shanshan and Wang, Zhicheng and Hao, Xueshi and Nguyen, Bao and Zhang, Xiaoyue and Bursulaya, Badry and DiDonato, Michael and Gordon, William and Baaten, Janine and Hill, Robert and Qiu, Minhua and Zhang, You-Qing and Espinola, Sheryll and Deaton, Lisa and Ha, Sukwon and Jia, Yong and Schumacher, Andrew and Colman, Karyn and Pan, Shifeng and McNamara, Peter and Meeusen, Shelly and Molteni, Valentina and Loren, Jon and Jin, Qihui and Ding, Qiang and Pan, Jianfeng and Mo, Tingting and Jacobsen, Kate and Lam, Thanh and Wu, Tom Y.-H. and Petrassi, Hank Michael and Liu, Bo and Nguyen-Tran, Vân and Kamireddy, Anwesh and Harb, George and Li, Jing and Shen, Weijun and Glynne, Richard and Laffitte, Bryan (2020) Selective DYRK1A inhibitor for the treatment of Type 1 Diabetes: Discovery of 6-azaindole derivative GNF2133. Journal of Medicinal Chemistry, 63 (6). pp. 2958-2973. ISSN 0022-26231520-4804

Liu, Zichuan and Tardat, Mathieu and Gill, Mark E and Royo, Helene and Thierry, Raphael and Ozonov, Evgeniy A and Peters, Antoine HFM (2020) SUMO ylated PRC 1 controls histone H3.3 deposition and genome integrity of embryonic heterochromatin. The EMBO Journal. pp. 1-24. ISSN 0261-4189

Lopez, John and Kumar, Ashish and Mahama , Alhassan and Fernando , Albericio and Beatriz , G. de la Torre (2020) N-Butylpyrrolidinone for Solid-Phase Peptide Synthesis is Environmentally Friendlier and Synthetically Better than DMF. ChemSusChem, 13 (19). pp. 5288-5294. ISSN 1864564X

Lopez, John and Bucher, Christoph and Albericio, Fernando and Garcia de la Torre, Beatriz and Kumar, Ashish and Alhassan, Mahama (2020) Successful Development of a Method for the Incorporation of Fmoc-Arg(Pbf)-OH in Solid-Phase Peptide Synthesis using N Butylpyrrolidinone (NBP) as a Green Solvent. Current Green Chemistry, 22 (10). pp. 3162-3169. ISSN 1463-92621463-9270

Lopez, John and Mahama , Alhassan and Kumar, Ashish and Albericio, Fernando and G. de la Torre, Beatriz (2020) Revisiting NO2 as Protecting group of Arginine in Solid-Phase Peptide Synthesis. International journal of molecular sciences, 21 (12). pp. 1-12. ISSN 1422-0067

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Lu, Haihui and Molony, Ryan and Chen, Dongshu and Jang, Sunyoung and Wolf, Babette and Ewert, Stefan and Meghan , Flaherty and Xu, Fangmin and Isim, Sinan and Shim, Yeonju and Dornelas, Christina and Balke, Nicole and Leber, Xavier Charles and Scharenberg, Meike and Koelln, Johanna and Choi, Eugene and Ward, Rebecca and Johnson, Jennifer and Calzascia, Thomas and Isnardi, Isabelle and Williams, Juliet and Van de Donk, Niels and Mutis, Tuna and Huet, Heather and Lees, Emma and Meyer, Matthew (2020) Development of anti-CD32b antibodies with enhanced Fc function for the treatment of B and plasma cell malignancies. Molecular cancer therapeutics, 19 (10). pp. 2089-2104. ISSN 1538-8514

Lu, Henry and Liu, Chen and Huynh, Hung and Le, Thi Bich Uyen and LaMarche, Matthew and Mohseni, Mori and Engelman, Jeffrey and Hammerman, Peter and Caponigro, Giordano and Hao, Huaixiang (2020) Resistance to allosteric SHP2 inhibition in FGFR-driven cancers through rapid feedback activation of FGFR. Oncotarget, 11 (3). pp. 265-281. ISSN 1949-2553

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Mann, Greg and Stanger, Frederic (2020) A Bio-logical Approach to Catalysis in the Pharmaceutical Industry. Chimia, 74 (5). pp. 407-417. ISSN 00094293

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Marie-Gabrielle , Braun and Jonathan, Latham and Louis, Diorazio and Kenneth, Fraunhoffer and John, Hayler and Matthew, Hickey and Lovelle, Lucie and Mark, McLaws and Andrew, Parsons and Paul, Richardson and Doru, Roiban and Philipp, Roosen and Alan, Steven and Jack, Terrett and Timothy, White and Jingjun, Yin (2020) Green Chemistry Articles of Interest to the Pharmaceutical Industry (24). Organic Process Research & Development, 24 (3). pp. 334-346. ISSN 1083-61601520-586X

Martin, Benjamin and Schenkel, Berthold and Ganiek, Maximilian and Djukanovic, Dimitrije and Knochel, Paul and Heinz, Benjamin (2020) Selective Acylation of Aryl- and Heteroarylmagnesium Reagents with Esters in Continuous Flow. Organic Letters, 22 (2). pp. 493-496. ISSN 1523-70601523-7052

Martin, Eric and Jansen, Hanneke (2020) Biased Diversity for Effective Virtual Screening. Journal of Chemical Information and Modeling, 60 (9). pp. 4116-4119. ISSN 1549-95961549-960X

Maser, Tyler and Zagorski, Joseph and Kelly, Shannon and Ostrander, Anna and Goodyke, Austin and Nagulapally, Abhinav and Bond, Jeffrey and Sholler, Giselle Saulnier (2020) The MDM2 inhibitor CGM097 combined with the BET inhibitor OTX015 induces cell death and inhibits tumor growth in models of neuroblastoma. Cancer Medicine. ISSN 2045-76342045-7634

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Middleton, Gary and Yang, Yiqun and Campbell, Katie and Millholland, John and Rangwala, Fatima and Corcoran, Ryan (2020) BRAF-mutant Transcriptional Subtypes Predict Outcome of Combined BRAF, MEK, and EGFR Blockade With Dabrafenib, Trametinib, and Panitumumab in Patients With Colorectal Cancer. Clinical cancer research. ISSN 1078-0432

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Vollmer, Tom and Zhou, Enhua and Rice, Dennis and Prasanna, Ganesh and Chen, Amy and Wilson, Chris (2020) Application of Cell Impedance as a Screening Tool to Discover Modulators of Intraocular Pressure. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 36 (5). pp. 269-281. ISSN 15577732

Vorherr, Thomas and Lewis, Ian and Wille, Roman Mariano and Lochmann, Thomas and Berghausen, Joerg and Huth, Felix and Schroer, Kirsten and Blanz, Joachim and Aichholz, Reiner and Schaefer, Michael (2020) On the importance of metabolic stability to achieve high oral exposures for cyclic peptides. American Journal of Medicinal Chemistry.

Vulic, Katarina and Caralli, Lisa (2020) From Candidate to Clinic: Strategies to Accelerate you Molecule's Development Path. Candidate to Clinic Webinar Executive Summary, n/a (n/a). pp. 1-10. ISSN n/a

van Groen, Bianca D. and Pilla Reddy, Venkatesh and Badee, Justine Marine and Olivares-Morales, Andrés and Johnson, Trevor N. and Nicolaï, Johan and Annaert, Pieter and Smith, Anna and de Wildt, Saskia N. and Knibbe, Catherijne A. J. and de Zwart, Loeckie (2020) Pediatric pharmacokinetics and dose predictions: a report of a satellite meeting to the 10th Juvenile Toxicity Symposium. Clinical and translational science. ISSN 1752-8062


Wagner, Julia A and Wong, Pamela and Schappe, Timothy and Berrien-Elliott, Melissa M and Cubitt, Celia and Jaeger, Natalia and Lee, Madeline and Keppel, Cassie R and Marin, Nancy D and Foltz, Jennifer A and Marsala, Lynne and Neal, Carly C and Sullivan, Ryan and Schneider, Stephanie E and Keppel, Molly P and Saucier, Nermina and Cooper, Megan A and Fehniger, Todd A (2020) Stage-Specific Requirement for Eomes in Mature NK Cell Homeostasis and Cytotoxicity. Cell reports, 31 (9). p. 107720. ISSN 2211-1247

Walles, Markus and End, Peter and Brown, Alan and Zimmerlin, Alfred Gilbert (2020) New Perspectives on Drug-Induced Liver Injury Risk Assessment of Acyl Glucuronides. Chem res tox, 33 (7). pp. 1551-1560. ISSN doi: 10.1021/acs.chemrestox.0c00131.

Wang, Shirley and Kulldorff, Martin and Poor, Stephen and Rice, Dennis and Banks, Angela and Li, Ning and Lii, Joyce and Gagne, Joshua J (2020) Screening medications for association with progression to wet age-related macular degeneration (AMD). Ophthalmology. ISSN 01616420

Wang, Xiaoliang and Perozzo, Remo and Amirshahrokhi, Keyvan and Kuchen, Stefan and Yousefi, Shida and Simon, Hans-Uwe and Loetscher, Pius and Gessier, Francois (2020) RIPK3-MLKL – Mediated neutrophil death requires concurrent activation of fibroblast activation protein alpha (FAP-α). The Journal of Immunology. ISSN 0022-17671550-6606

Wang, Zhong-Yi and Leushkin, Evgeny and Liechti, Angélica and Ovchinnikova, Svetlana and Mößinger, Katharina and Brüning, Thoomke and Rummel, Coralie and Grützner, Frank and Cardoso-Moreira, Margarida and Janich, Peggy and Gatfield, David and Diagouraga, Boubou and de Massy, Bernard and Gill, Mark E and Peters, Antoine H F M and Anders, Simon and Kaessmann, Henrik (2020) Transcriptome and translatome co-evolution in mammals. Nature, 588 (7839). pp. 642-647. ISSN 1476-4687

Ward, Lesley A and Lee, Dennis SW and Sharma, Anshu and Wang, Angela and Naouar, Ikbel and Ma, Xianjie I and Pikor, Natalia and Nuesslein-Hildesheim, Barbara and Ramaglia, Valeria and Gommerman, Jennifer L (2020) A murine model of meningeal inflammation and subpial demyelination identifies an anti-MOG independent mechanism of cortical injury that is inhibited by Siponimod therapy. JCI insight.

Wartchow, Charles and Kane, Joshua and Shaul, Jacob and Frank, Andreas and Knapp, Mark and Bussiere, Dirksen and Ornelas, Elizabeth and Hyrina, Anastasia (2020) eLive revised manuscript: A POLYOMAVIRUS PEPTIDE BINDS TO THE CAPSID VP1 PORE AND HAS POTENT ANTIVIRAL ACTIVITY AGAINST BK AND JC POLYOMAVIRUSES. ELife., 9. ISSN 2050-084X

Wenzel, Jan and Richter, Marius and Bettoni, Carla and Vogt, Miriam A and Natsagdorj, Rentsenkhand and Huber, Gianna and Brands, Josefine and Assmann, Julian C and Lembrich, Beate and Stölting, Ines and Sedlacik, Jan and Fiehler, Jens and Ludewig, Peter and Wegmann, Michael and MüllerFielitz, Helge and Wlather, Thomas and Schmidt, Kjestine and König, Gabriele M and Kostenis, Evi and Raasch, Walter and deWit, Cor and Gass, Peter and Offermanns, Stefan and Wagner, Carsten A and Schwaninger, Markus (2020) Behavioral, respiratory and metabolic consequences of impaired cerebrovascular reactivity. Proceedings of the National Academy of Sciences of the United States of America PNAS.. ISSN 1091-6490; 0027-8424

Wewers, Martin and Czyz, Stefan and Finke, Jan and John, Edgar and Van Eerdenbrugh, Bernard and Juhnke, Michael and Bunjes, Heike and Kwade, Arno (2020) Influence of Formulation Parameters on Redispersibility of Naproxen Nanoparticles from Granules Produced in a Fluidized Bed Process. Pharmaceutics, 12 (n/a). p. 363. ISSN 1999-4923

Widler, Leo and Amadeu, Nader and Augner, Sven and Janiak, Christoph and Hägele, Gerhard (2020) Symmetric Geminal Bisphosphinic Acids RR´C[P(CH3)(O)OH]2 - NMR and Analytical Studies. Phosphorus, Sulfur, and Silicon and the Related Elements. ISSN 1042-65071563-5325

Wilcken, Rainer and Rodde, Stephane and Udvarhelyi, Aniko (2020) ReSCoSS: A Flexible Quantum Chemistry Workflow Identifying Relevant Solution Conformers of Drug-like Molecules. Journal of computer-aided molecular design.

Wong, Connie and Baum, Jason and Beste, Michael and Bharani Dharan, Bharani and Wang, Amanda and Wang, Xiaoshan and Silvestro, Angela and Prescott, Margaret and Krajkovich, Lynne and Dugan, Margaret and Ridker, Paul and Martin, Ann Marie and Svensson, Eric and Xu, Siyan (2020) Inhibition of IL-1β by canakinumab may be effective against diverse molecular subtypes of lung cancer: An exploratory analysis of the CANTOS trial. Cancer research, 80. pp. 5597-5605. ISSN 1538-7445

Woollam, Grahame and Das, Partha P. and Mugnaioli, Enrico and Andrusenko, Iryna and Galanis, Athanassios S. and Jacco, Van De Streek (ext.) and Nicolopoulos, Stavros and Gemmi, Mauro and Wagner, Beatrix (2020) Structural Analysis of Metastable Pharmaceutical Loratadine Form II, by 3D Electron Diffraction and DFT+D Energy Minimisation. CrystEngComm. ISSN 1466-8033

Wu, Bin and Zhang, Sisi and Hong, Tao and Zhou, Yizong and Wang, Hui and Shi, Min and Yang, Hongwei and Tian, Xiangguang and Guo, Jing and Bian, Jianwei and Roache, James and Delgado, Pete and Mo, Ruowei and Fridrich, Cary and Gao, Feng and Wang, Joseph (2020) Development of a Practical Synthesis of an FXI (Factor XI) Inhibitor. Organic process research & development, 24 (11). pp. 2780-2788.

Wu, Quanbing and Li, Lei and Li, Bin and Chen, Like and Wu, Bin and Wang, Xianwen and Guo, Tina (2020) Process Development for the Synthesis of a -monobactam antibiotic - LYS228. Organic Process Research & Development, 24 (3). pp. 363-370. ISSN 1083-61601520-586X

Wuersch, Kuno and Parrula, Cecilia and Dincer, Zuhal and de Vera Mudry, Maria Cristina and Geoly, Frank and Mysore, Jagannatha (2020) Toxicologic Pathology Forum: Opinion on Obligatory Microscopic Examination of Intermediate-Dose Groups in Toxicity Studies With Biotherapeutics in Cynomolgus Monkeys. Toxicologic Pathology, 48 (8). pp. 939-943. ISSN 15331601


Xing, Jimmy and Loureiro, Joe and Patel, Michael and Mikhailov, Dmitri and Gusev, Arkady (2020) Evaluation of a novel blood microsampling device for clinical trial sample collection and protein biomarker analysis. Bioanalysis, 12. pp. 919-935. ISSN 1757-6199

Xue, J and Domingo-Almenara, X and Fuijas, C and Palermo, A and Rinschen, M and Benton, H P and Isbell, John and Siuzdak, G (2020) Enhanced electrospray in-source fragmentation for higher sensitivity data independent acquisition and autonomous METLIN molecular identification. Analytical Chemistry, 92 (8). pp. 6051-6059. ISSN 0003-27001520-6882


Yang, Haisheng and Büttner, Alexander and Albiol, Laia and Julien, Catherine and Thiele, Tobias and Figge, Christine and Kramer, Ina and Kneissel, Michaela and Duda, Georg N. and Checa, Sara and Willie, Bettina M. (2020) Cortical bone adaptation to a moderate level of mechanical loading in male Sost deficient mice. Scientific reports, 10 (1). pp. 22299-22316.

Yang, J and Balog, B and Deng , K and Hanzlicek, B and Rietsch, A and Kuang, M and Hatakeyama, Shinji and Trifilieff, Estelle and Zhu, H and Damaser, MS (2020) Therapeutic potential of muscle growth promoters in a stress urinary incontinence model. American Journal of Physiology-Renal Physiology, 319 (3). F436-F446. ISSN 1931-857X1522-1466

Yi, John and Russo, Melissa and Raja, Shruti and Massey, Janice and Juel, Vern and Shin, Jay and Hobson-Webb, Lisa and Gable, Karissa and Guptill, Jeffrey (2020) Inhibition of the transcription factor ROR-γ reduces pathogenic Th17 cells in acetylcholine receptor antibody positive myasthenia gravis. Experimental Neurology, 325 (March ). pp. 1-8. ISSN 0014-4886

Yokokawa, Fumiaki (2020) Recent progress on phenotype-based discovery of dengue inhibitors. RSC Medicinal Chemistry.


Zaidman, Nathan A and Tomilin , Viktor and Damarla, Mahendra and Tidmore, Josephine and Capen , Diane and Brown, Dennis and Pochynyuk, Oleh and Pluznick, Jennifer L (2020) Adhesion-GPCR Gpr116 (ADGRF5) is a Regulator of Urine Acidification and Surface Expression of the Vacuolar-type H+-ATPase in Renal α-Intercalated Cells. Proceedings of the National Academy of Sciences of the United States of America PNAS..

Zhu, Liang and Glick, Jim and Flarakos, Jimmy (2020) Bioanalytical Challenges in Support of Complex Modalities of Antibody-Based Therapeutics. AAPS Journal, 22 (6). pp. 130-135. ISSN 15507416

This list was generated on Wed Jun 29 18:46:54 2022 UTC.


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