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Internship Report for Summer-Pranav Sahasrabudhe

Sahasrabudhe, Pranav and Banks, Angela and Rice, Dennis (2020) Internship Report for Summer-Pranav Sahasrabudhe. Internship Report for Summer-Pranav Sahasrabudhe .

Abstract

In the last report we touched upon the basics of Single-Cell technology, its working and methods
used to analyze the data. It was mentioned in the future development section that the focus
would be to evaluate R packages in order to provide additional utilities and biological insights
compared to the standard Seurat [1] workflow for other major steps of single-cell RNA-seq
analysis, including clustering, cell type annotation and additional downstream analysis beyond
differential expression (i.e. Pseudotime analysis, enrichment analysis, receptor-ligand
enrichment, etc.) In the present report, we focus on utilities provided through packages like SC3
[2], scPred [3] for clustering and annotations respectively.

Item Type: Article
Date Deposited: 28 Nov 2020 00:45
Last Modified: 28 Nov 2020 00:45
URI: https://oak.novartis.com/id/eprint/43433

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