Items where Year is 2004
A
Altmann, Eva, Jacob, Sandra and Missbach, Martin (2004) Novel purine nitrile derived inhibitors of the cysteine protease cathepsin K. Journal of Medicinal Chemistry, 47 (24). pp. 5833-5836. ISSN 0022-2623
Altmann, Karl-Heinz, Floersheimer, Andreas, O'Reilly, Terence and Wartmann, Markus (2004) 4. The natural products epothilones A and B as lead structures for anticancer drug discovery: chemistry, biology, and SAR studies. Progress in Medicinal Chemistry, 42. pp. 171-205. ISSN 0079-6468
Atadja, Peter, Gao, Lin, Kwon, Paul, Trogani, Nancy, Walker, Heather, Hsu, Meier, Yeleswarapu, N., Chandramouli, Nagarajan, Perez, Lawrence, Versace, Richard, Wu, Arthur, Sambucetti, Lidia, Lassota, Piotr, Cohen, Dalia, Bair, Kenneth, Wood, Alexander and Remiszewski, Stacy (2004) Selective growth inhibition of tumor cells by a novel histone deacetylase inhibitor, NVP-LAQ824. Cancer Research, 64 (2). pp. 689-695. ISSN 0008-5472
Atadja, Peter, Hsu, Meier, Kwon, Paul, Trogani, Nancy, Bhalla, Kapil and Remiszewski, Stacy (2004) Molecular and cellular basis for the anti-proliferative effects of the HDAC inhibitor LAQ824. Novartis Foundation Symposium, 259. 249-266; discussion 266-268; 285-288. ISSN 1528-2511
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Bakhtiar, Ray, Ramos, Luis and Tse, Francis (2004) Toxicokinetic assessment of methylphenidate (Ritalin) in a 13-week oral toxicity study in dogs. Biomedical Chromatography, 18 (1). pp. 45-50. ISSN 0269-3879
Bakhtiar, Ray and Tse, Francis (2004) Toxicokinetic assessment of methylphenidate (Ritalin) enantiomers in pregnant rats and rabbits. Biomedical chromatography : BMC, 18 (5). pp. 275-281. ISSN 0269-3879
Bandell, Michael, Story, Gina, Hwang, Sun Wook, Viswanath, Veena, Eid, Samer, Petrus, Matthew, Earley, Taryn and Patapoutian, Ardem (2004) Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin. Neuron, 41 (6). pp. 849-857. ISSN 0896-6273
Barrera, Leah, Benner, Chris, Tao, Yong-Chuan, Winzeler, Elizabeth and Zhou, Yingyao (2004) Leveraging two-way probe-level block design for identifying differential gene expression with high-density oligonucleotide arrays. BMC Bioinformatics, 5 (1). p. 42. ISSN 1471-2105
Beckmann, Nicolau, Cannet, Catherine, Zurbruegg, Stefan, Rudin, Markus and Tigani, Bruno (2004) Proton MRI of lung parenchyma reflects allergen-induced airway remodeling and endotoxin-aroused hyporesponsiveness: a step toward ventilation studies in spontaneously breathing rats. Magnetic Resonance in Medicine: official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine, 52 (2). pp. 258-268. ISSN 0740-3194
Beckmann, Nicolau, Laurent, Didier, Tigani, Bruno, Panizzutti, Rogerio and Rudin, Markus (2004) Magnetic resonance imaging in drug discovery: lessons from disease areas. Drug Discovery today, 9 (1). pp. 35-42. ISSN 1359-6446
Bernhard, Michel, Takeda, Kenneth, Keller, Caroline, Haslebacher, Mirko, Lambrou, George N. and Trendelenburg, Anne-Ulrike (2004) 3H-Noradrenaline release from mouse iris-ciliary body: role of presynaptic muscarinic heteroreceptors. Naunyn-Schmiedeberg's Archives of Pharmacology, 370 (4). pp. 305-313. ISSN 0028-1298
Billich, Andreas, Bilban, Melitta, Meisner, Nicole-Claudia, Nussbaumer, Peter, Neubauer, Andreas, Jager, Stefan and Auer, Manfred (2004) Confocal fluorescence detection expanded to UV excitation: the first continuous fluorimetric assay of human steroid sulfatase in nanoliter volume. Assay and Drug Development Technologies, 2 (1). pp. 21-30. ISSN 1540-658X
Billich, Andreas, Meingassner, Josef, Nussbaumer, Peter, Desrayaud, Sandrine, Lam, Charles, Winiski, Anthony and Schreiner, Erwin (2004) 6-[2-(adamantylidene)-hydroxybenzoxazole]-O-sulfamate, a steroid sulfatase inhibitor for the treatment of androgen- and estrogen-dependent diseases. The Journal of Steroid Biochemistry and Molecular Biology, 92 (1-2). pp. 29-37. ISSN 0960-0760
Bittinger, Mark, McWhinnie, Elizabeth, Meltzer, Jodi, Iourgenko, Vadim, Latario, Brian, Liu, Xiulin, Chen, Chein Hwa, Song, Chuanzheng, Garza, Dan and Labow, Mark (2004) Activation of cAMP response element-mediated gene expression by regulated nuclear transport of TORC proteins. Current Biology : CB, 14 (23). pp. 2156-2161. ISSN 0960-9822
Brill, Laurence, Salomon, Arthur, Ficarro, Scott, Mukherji, Mridul, Stettler-Gill, Michelle and Peters, Eric (2004) Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry. Analytical Chemistry, 76 (10). pp. 2763-2772. ISSN 0003-2700
Brinkmann, Volker (2004) FTY720: mechanism of action and potential benefit in organ transplantation. Yonsei Medical Journal, 45 (6). pp. 991-997. ISSN 0513-5796
Brinkmann, Volker, Cyster, Jason G and Hla, Timothy (2004) FTY720: sphingosine 1-phosphate receptor-1 in the control of lymphocyte egress and endothelial barrier function. American Journal of Transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 4 (7). pp. 1019-1025. ISSN 1600-6135
Burkhart, Christoph, Heusser, Christoph, Morris, Randall, Raulf, Friedrich, Weckbecker, Gisbert, Weitz Schmidt, Gabriele and Welzenbach, Karl (2004) Pharmacodynamics in the development of new immunosuppressive drugs. Therapeutic Drug Monitoring, 26 (6). pp. 588-592. ISSN 0163-4356
Butler, Jeannene, Lana, Diana, Round, Oliver and La Montagne, Kenneth (2004) Functional characterization of sphingosine 1-phosphate receptor agonist in human endothelial cells. Prostaglandins & other Lipid Mediators, 73 (1-2). pp. 29-45. ISSN 1098-8823
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Carre, Adeline, Graf, Christine, Stora, Samantha, Mechtcheriakova, Diana, Csonga, Robert, Urtz, Nicole, Billich, Andreas, Baumruker, Thomas and Bornancin, Frederic (2004) Ceramide kinase targeting and activity determined by its N-terminal pleckstrin homology domain. Biochemical and Biophysical Research Communications, 324 (4). pp. 1215-1219. ISSN 0006-291X
Chao, Sheng Hao, Harada, Josephine, Hyndman, Francie, Gao, Xiaoqi, Nelson, Christian, Chanda, Sumit and Caldwell, Jeremy (2004) PDX1, a cellular homeoprotein, binds to and regulates the activity of human cytomegalovirus immediate early promoter. The Journal of Biological Chemistry, 279 (16). pp. 16111-16120. ISSN 0021-9258
Cryan, John F., Kelly, Peter, Chaperon, Frederique, Gentsch, Conrad, Mombereau, Cedric, Lingenhoehl, Kurt, Froestl, Wolfgang, Bettler, Bernhard, Kaupmann, Klemens and Spooren, Will P J M (2004) Behavioral characterization of the novel GABAB receptor-positive modulator GS39783 (N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): anxiolytic-like activity without side effects associated with baclofen or benzodiazepines. The Journal of Pharmacology and Experimental therapeutics, 310 (3). pp. 952-963. ISSN 0022-3565
Cryan, John F. and Mombereau, Cedric (2004) In search of a depressed mouse: utility of models for studying depression-related behavior in genetically modified mice. Molecular Psychiatry, 9 (4). pp. 326-357. ISSN 1359-4184
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Dev, Kumlesh K. (2004) Making protein interactions druggable: targeting PDZ domains. Nature Reviews Drug Discovery, 3 (12). pp. 1047-1056. ISSN 1474-1776
Dorn, Gabriele, Patel, Sadhana, Wotherspoon, Glen, Hemmings-Mieszczak, Maja, Barclay, Jane, Natt, Francois, Martin, Pierre, Bevan, Stuart, Fox, Alyson, Ganju, Pam, Wishart, William L. and Hall, Jonathan (2004) siRNA relieves chronic neuropathic pain. Nucleic Acids Research, 32 (5). e49. ISSN 1362-4962
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Ellis, Karen Margaret, Cannet, Catherine, Mazzoni, Lazzaro and Fozard, John R. (2004) Airway hyperresponsiveness to bradykinin induced by allergen challenge in actively sensitised Brown Norway rats. Naunyn-Schmiedeberg's Archives of Pharmacology, 369 (2). pp. 166-178. ISSN 0028-1298
End, Nicole, Furet, Pascal, Vancampenhout, Nathalie, Wartmann, Markus and Altmann, Karl-Heinz (2004) Total synthesis and biological evaluation of a C(10)/C(12)-phenylene-bridged analog of epothilone D. Chemistry & Biodiversity, 1 (11). pp. 1771-1784. ISSN 1612-1880
Enz, Albert, Chappuis, Alain and Dattler, Andre (2004) A simple, rapid and sensitive method for simultaneous determination of rivastigmine and its major metabolite NAP 226-90 in rat brain and plasma by reversed-phase liquid chromatography coupled to electrospray ionization mass spectrometry. Biomedical Chromatography, 18 (3). pp. 160-166. ISSN 0269-3879
Enz, Albert and Gentsch, Conrad (2004) Co-administration of memantine has no effect on the in vitro or ex vivo determined acetylcholinesterase inhibition of rivastigmine in the rat brain. Neuropharmacology, 47 (3). pp. 408-413. ISSN 0028-3908
Ettmayer, Peter, Amidon, Gordon, Clement, Bernd and Testa, Bernard (2004) Lessons learned from marketed and investigational prodrugs. Journal of Medicinal Chemistry, 47 (10). pp. 2393-2404. ISSN 0022-2623
Ettmayer, Peter, Billich, Andreas, Baumruker, Thomas, Mechtcheriakova, Diana, Schmid, Heide and Nussbaumer, Peter (2004) Fluorescence-labeled sphingosines as substrates of sphingosine kinases 1 and 2. Bioorganic & Medicinal Chemistry Letters, 14 (6). pp. 1555-1558. ISSN 0960-894X
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Finelli, Alyce, Kelkar, Anju, Song, Ho-Juhn, Yang, Haidi and Konsolaki, Mary (2004) A model for studying Alzheimer's Abeta42-induced toxicity in Drosophila melanogaster. Molecular and Cellular Neurosciences, 26 (3). pp. 365-375. ISSN 1044-7431
Fozard, John R., Buescher, Heinz, Farr, David Colin and Mazzoni, Lazzaro (2004) Suppression of histamine-induced tachypnoea in the rhesus monkey by sibenadet: no role for dopamine D2 receptors. Autonomic & Autacoid Pharmacology, 24 (1). pp. 9-16. ISSN 1474-8665
Furet, Pascal, Imbach, Patricia, Noorani, Maria, Koeppler, Juergen, Laumen, Kurt, Lang, Marc, Guagnano, Vito, Fuerst, Peter, Roesel, Johannes, Zimmermann, Johann and Garcia-Echeverria, Carlos (2004) Entry into a new class of potent proteasome inhibitors having high antiproliferative activity by structure-based design. Journal of Medicinal Chemistry, 47 (20). pp. 4810-4813. ISSN 0022-2623
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Ganju, Pam and Hall, Jonathan (2004) Potential applications of siRNA for pain therapy. Expert Opinion on Biological Therapy, 4 (4). pp. 531-542. ISSN 1471-2598
Garcia-Echeverria, Carlos, Pearson, Mark Andrew, Marti, Andreas, Meyer, Thomas, Mestan, Juergen, Zimmermann, Johann, Gao, Jiaping, Brueggen, Josef, Capraro, Hans-Georg, Cozens, Robert, Evans, Dean Brent, Fabbro, Doriano, Furet, Pascal, Porta, Diana Graus, Liebetanz, Janis, Martiny-Baron, Georg, Ruetz, Stephan and Hofmann, Francesco (2004) In vivo antitumor activity of NVP-AEW541-A novel, potent, and selective inhibitor of the IGF-IR kinase. Cancer Cell, 5 (3). pp. 231-239. ISSN 1535-6108
Glick, Meir, Klon, Anthony, Acklin, Pierre and Davies, John (2004) Enrichment of extremely noisy high-throughput screening data using a naïve Bayes classifier. Journal of Biomolecular Screening : the official journal of the Society for Biomolecular Screening, 9 (1). pp. 32-36. ISSN 1087-0571
Grassberger, Maximilian, Steinhoff, M, Schneider, Dirk and Luger, T A (2004) Pimecrolimus -- an anti-inflammatory drug targeting the skin. Experimental Dermatology, 13 (12). pp. 721-730. ISSN 0906-6705
Gremlich, Hans-Ulrich, Martinez, Vicente, Kneuer, Rainer, Kinzy, Willy, Weber, Eckhard, Pfannkuche, Hans-Juergen and Rudin, Markus (2004) Noninvasive assessment of gastric emptying by near-infrared fluorescence reflectance imaging in mice: pharmacological validation with tegaserod, cisapride, and clonidine. Molecular Imaging : official journal of the Society for Molecular Imaging, 3 (4). pp. 303-311. ISSN 1535-3508
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Harant, Hanna and Lindley, Ivan-J.D. (2004) Negative cross-talk between the human orphan nuclear receptor Nur77/NAK-1/TR3 and nuclear factor-kappaB. Nucleic Acids Research, 32 (17). pp. 5280-5290. ISSN 1362-4962
Hersperger, Rene, Buchheit, Karl-Heinz, Cammisuli, Salvatore, Enz, Albert, Lohse, Olivier, Ponelle, Monique, Schuler, Walter, Schweitzer, Alain, Walker, Christoph, Zehender, Hartmut, Zenke, Gerhard, Zimmerlin, Alfred Gilbert, Zollinger, Markus, Mazzoni, Lazzaro and Fozard, John R. (2004) A locally active antiinflammatory macrolide (MLD987) for inhalation therapy of asthma. Journal of Medicinal Chemistry, 47 (20). pp. 4950-4957. ISSN 0022-2623
Hofbauer, Christian, Lohninger, Hans and Aszodi, Andras (2004) SURFCOMP: a novel graph-based approach to molecular surface comparison. Journal of Chemical Information and Computer Sciences, 44 (3). pp. 837-847. ISSN 0095-2338
Horvath, Amarylla, Nussbaumer, Peter, Wolkin, Barbara and Billich, Andreas (2004) 2-(1-adamantyl)-4-(thio)chromenone-6-carboxylic acids: potent reversible inhibitors of human steroid sulfatase. Journal of Medicinal Chemistry, 47 (17). pp. 4268-4276. ISSN 0022-2623
Hoyer, Daniel, Nunn, Caroline, Hannon, Jason, Schoeffter, Philippe, Feuerbach, Dominik, Schuepbach, Edi, Langenegger, Daniel, Bouhelal, Rochdi, Hurth, Konstanze, Neumann, Peter, Troxler, Thomas J. and Pfaeffli, Paul (2004) SRA880, in vitro characterization of the first non-peptide somatostatin sst(1) receptor antagonist. Neuroscience Letters, 361 (1-3). pp. 132-135. ISSN 0304-3940
Hu, Chii-Whei, Webb, Randy and Jeng, Arco (2004) Synergistic stimulation of aldosterone production in human adrenocortical carcinoma NCI-H295R cells by endothelin-1 and angiotensin II. Journal of Cardiovascular Pharmacology, 44 Suppl 1. S289-S292. ISSN 1533-4023
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Jenkins, Jeremy, Glick, Meir and Davies, John (2004) A 3D similarity method for scaffold hopping from known drugs or natural ligands to new chemotypes. Journal of Medicinal Chemistry, 47 (25). pp. 6144-6159. ISSN 0022-2623
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Kallen, Joerg, Schlaeppi, Jean-Marc, Bitsch, Francis, Filipuzzi, Ireos, Schilb, Alain, Riou, Virginie, Graham, Alexander, Strauss, Andre, Geiser, Martin and Fournier, Brigitte (2004) Evidence for ligand-independent transcriptional activation of the human estrogen-related receptor alpha (ERRalpha): crystal structure of ERRalpha ligand binding domain in complex with peroxisome proliferator-activated receptor coactivator-1alpha. The Journal of Biological Chemistry, 279 (47). pp. 49330-49337. ISSN 0021-9258
Kirkham, Paul, Spooner, Gillian, Rahman, Irfan and Rossi, Adriano (2004) Macrophage phagocytosis of apoptotic neutrophils is compromised by matrix proteins modified by cigarette smoke and lipid peroxidation products. Biochemical and Biophysical Research Communications, 318 (1). pp. 32-37. ISSN 0006-291X
Klon, Anthony, Glick, Meir and Davies, John (2004) Application of machine learning to improve the results of high-throughput docking against the HIV-1 protease. Journal of Chemical Information and Computer Sciences, 44 (6). pp. 2216-2224. ISSN 0095-2338
Klon, Anthony, Glick, Meir and Davies, John (2004) Combination of a naive Bayes classifier with consensus scoring improves enrichment of high-throughput docking results. Journal of Medicinal Chemistry, 47 (18). pp. 4356-4359. ISSN 0022-2623
Klon, Anthony, Glick, Meir, Thoma, Mathis, Acklin, Pierre and Davies, John (2004) Finding more needles in the haystack: A simple and efficient method for improving high-throughput docking results. Journal of Medicinal Chemistry, 47 (11). pp. 2743-2749. ISSN 0022-2623
Kneissel, Michaela, Luong-Nguyen, Ngoc-Hong, Baptist, Myma, Cortesi, Reto, Zumstein-Mecker, Sabine, Kossida, Sophia, O'Reilly, Terry, Lane, Heidi and Susa Spring, Mira (2004) Everolimus suppresses cancellous bone loss, bone resorption, and cathepsin K expression by osteoclasts. Bone, 35 (5). pp. 1144-1156. ISSN 8756-3282
Knochenmuss, Richard (2004) Photoionization pathways and free electrons in UV-MALDI. Analytical Chemistry, 76 (11). pp. 3179-3184. ISSN 0003-2700
Kramer, Richard and Cohen, Dalia (2004) Functional genomics to new drug targets. Nature Reviews Drug Discovery, 3 (11). pp. 965-972. ISSN 1474-1776
Kretz, Olivier, Weiss, Markus, Schumacher, Martin and Gross, Gerhard (2004) In vitro blood distribution and plasma protein binding of the tyrosine kinase inhibitor imatinib and its active metabolite, CGP74588, in rat, mouse, dog, monkey, healthy humans and patients with acute lymphatic leukaemia. British journal of clinical pharmacology, 58 (2). pp. 212-216. ISSN 0306-5251
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Lake, Philip, De Leo, Jeffrey, Cerasoli, Frank, Logdberg, Lennart, Weetall, Marla and Handley, Dean (2004) Pharmacodynamic evaluation of the neutralization of endotoxin by PMX622 in mice. Antimicrobial Agents and Chemotherapy, 48 (8). pp. 2987-2992. ISSN 0066-4804
Lametschwandtner, Guenther, Biedermann, Tilo, Schwaerzler, Christoph, Gunther, Claudia, kund, julia, Fassl, Sandra, Hinteregger, Sonja, Carballido-Perrig, Nicole, Szabo, Susanne, Glimcher, Laurie and Carballido, Jose (2004) Sustained T-bet expression confers polarized human TH2 cells with TH1-like cytokine production and migratory capacities. The Journal of Allergy and Clinical Immunology, 113 (5). pp. 987-994. ISSN 0091-6749
Lecourtier, Lucas, Neijt, Hans Ch. and Kelly, Peter (2004) Habenula lesions cause impaired cognitive performance in rats: implications for schizophrenia. The European Journal of Neuroscience, 19 (9). pp. 2551-2560. ISSN 0953-816X
Lee, Christian, Wood, Michelle, Ng, Kenneth, Andersen, Carsten, Liu, Yi, Luginbuhl, Peter, Spraggon, Glen and Katagiri, Fumiaki (2004) Crystal structure of the type III effector AvrB from Pseudomonas syringae. Structure (London, England : 1993), 12 (3). pp. 487-494. ISSN 0969-2126
Li, Bing, Liu, Y, Uno, Tetsuo and Gray, Nathanael (2004) Creating chemical diversity to target protein kinases. Combinatorial Chemistry & High Throughput Screening, 7 (5). pp. 453-472. ISSN 1386-2073
Linton, Steven D, Aja, Teresa, Allegrini, Peter Roland, Deckwerth, Thomas L, Diaz, Jose-Luis, Hengerer, Bastian, Herrmann, Julia, Jahangiri, Kathy G, Kallen, Joerg, Karanewsky, Donald S, Meduna, Steven P, Nalley, Kip, Robinson, Edward D, Roggo, Silvio, Rovelli, Giorgio, Sauter, Andre, Sayers, Robert O, Schmitz, Albert, Smidt, Robert, Ternansky, Robert J, Tomaselli, Kevin J, Ullman, Brett R, Wiessner, Christoph and Wu, Joe C (2004) Oxamyl dipeptide caspase inhibitors developed for the treatment of stroke. Bioorganic & Medicinal Chemistry Letters, 14 (10). pp. 2685-2691. ISSN 0960-894X
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Mahe, Cecile, Bernhard, Michel, Bobirnac, Ionel, Keser, Corinna, Loetscher, Erika, Feuerbach, Dominik, Dev, Kumlesh K. and Schoeffter, Philippe (2004) Functional expression of the serotonin 5-HT7 receptor in human glioblastoma cell lines. British Journal of Pharmacology, 143 (3). pp. 404-410. ISSN 0007-1188
Mahe, Cecile, Loetscher, Erika, Feuerbach, Dominik, Mueller, Werner, Seiler, Max Peter and Schoeffter, Philippe (2004) Differential inverse agonist efficacies of SB-258719, SB-258741 and SB-269970 at human recombinant serotonin 5-HT7 receptors. European Journal of Pharmacology, 495 (2-3). pp. 97-102. ISSN 0014-2999
Majumdar, Tapan, Vedananda, Sunanda and Tse, Francis (2004) Rapid analysis of MMI270B, an inhibitor of matrix metalloproteases in human plasma by liquid chromatography-tandem mass spectrometry: matrix interference in patient samples. Biomedical Chromatography, 18 (2). pp. 77-85. ISSN 0269-3879
Majumdar, Tapan, Wu, Shari, Vedananda, Sunanda and Tse, Francis (2004) Determination of LAG078, a lipid-lowering compound, in dog plasma using liquid chromatography-tandem mass spectrometry: application in a toxicokinetic study. Journal of Pharmaceutical and Biomedical Analysis, 35 (4). pp. 853-866. ISSN 0731-7085
Manley, Paul W., Breitenstein, Werner, Brueggen, Josef, Cowan-Jacob, Sandra W, Furet, Pascal, Mestan, Juergen and Meyer, Thomas (2004) Urea derivatives of STI571 as inhibitors of Bcr-Abl and PDGFR kinases. Bioorganic & Medicinal Chemistry Letters, 14 (23). pp. 5793-5797. ISSN 0960-894X
Mason, Daniel, Ek, Jared, Peters, Eric and Harris, Jennifer (2004) Substrate profiling of deubiquitin hydrolases with a positional scanning library and mass spectrometry. Biochemistry, 43 (21). pp. 6535-6544. ISSN 0006-2960
Mastyugin, Vladimir, McWhinnie, Elizabeth, Labow, Mark and Buxton, Francis (2004) A quantitative high-throughput endothelial cell migration assay. Journal of Biomolecular Screening : the official journal of the Society for Biomolecular Screening, 9 (8). pp. 712-718. ISSN 1087-0571
Matsumoto, Yuji, Hof, Akiko, Baumlin, Yves, Mueller, Matthias and Hof, Robert (2004) Differential effects of everolimus and cyclosporine A on intimal alpha-actin-positive cell dynamics of carotid allografts in mice. Transplantation, 78 (3). pp. 345-351. ISSN 0041-1337
Mccombie, Gregor and Knochenmuss, Richard (2004) Small-molecule MALDI using the matrix suppression effect to reduce or eliminate matrix background interferences. Analytical Chemistry, 76 (17). pp. 4990-4997. ISSN 0003-2700
Meisner, Nicole-Claudia, Hackermüller, Jörg, Uhl, Volker, Aszódi, András, Jaritz, Markus and Auer, Manfred (2004) mRNA openers and closers: modulating AU-rich element-controlled mRNA stability by a molecular switch in mRNA secondary structure. ChemBioChem : a European journal of chemical biology, 5 (10). pp. 1432-1447. ISSN 1439-4227
Meisner, Nicole-Claudia, Hintersteiner, Martin, Uhl, Volker, Weidemann, Thomas, Schmied, Mario, Gstach, Hubert and Auer, Manfred (2004) The chemical hunt for the identification of drugable targets. Current Opinion in Chemical Biology, 8 (4). pp. 424-431. ISSN 1367-5931
Metzler, Barbara, Gfeller, Patrick, Bigaud, Marc, Li, Jianping, Wieczorek, Grazyna, Heusser, Christoph, Lake, Philip and Katopodis, Andreas (2004) Combinations of anti-LFA-1, everolimus, anti-CD40 ligand, and allogeneic bone marrow induce central transplantation tolerance through hemopoietic chimerism, including protection from chronic heart allograft rejection. Journal of Immunology (Baltimore, Md. : 1950), 173 (11). pp. 7025-7036. ISSN 0022-1767
Molteni, Valentina, He, Xiaohui, Nabakka, Juliet, Yang, Kunyong, Kreusch, Andreas, Gordon, P., Bursulaya, Badry, Warner, Ian, Shin, Tanya, Biorac, Tanya, Ryder, Neil, Goldberg, Ronald, Doughty, John and He, Yun (2004) Identification of novel potent bicyclic peptide deformylase inhibitors. Bioorganic & Medicinal Chemistry Letters, 14 (6). pp. 1477-1481. ISSN 0960-894X
Mombereau, Cedric, Kaupmann, Klemens, Froestl, Wolfgang, Sansig, Gilles, Van Der Putten, P. Herman and Cryan, John F. (2004) Genetic and pharmacological evidence of a role for GABA(B) receptors in the modulation of anxiety- and antidepressant-like behavior. Neuropsychopharmacology: official publication of the American College of Neuropsychopharmacology, 29 (6). pp. 1050-1062. ISSN 0893-133X
Mombereau, Cedric, Kaupmann, Klemens, Van Der Putten, P. Herman and Cryan, John F. (2004) Altered response to benzodiazepine anxiolytics in mice lacking GABA B(1) receptors. European Journal of Pharmacology, 497 (1). pp. 119-120. ISSN 0014-2999
Muckenschnabel, Ingo, Falchetto, Rocco Angelo, Mayr, Lorenz and Filipuzzi, Ireos (2004) SpeedScreen: label-free liquid chromatography-mass spectrometry-based high-throughput screening for the discovery of orphan protein ligands. Analytical Biochemistry, 324 (2). pp. 241-249. ISSN 0003-2697
Mueggler, Thomas, Meyer-Luehmann, Melanie, Rausch, Martin, Staufenbiel, Matthias, Jucker, Mathias and Rudin, Markus (2004) Restricted diffusion in the brain of transgenic mice with cerebral amyloidosis. The European Journal of Neuroscience, 20 (3). pp. 811-817. ISSN 0953-816X
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Neumann, Ulf, Kubota, Hisashi, Frei, Karl, Ganu, Vishwas and Leppert, David (2004) Characterization of Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2, a fluorogenic substrate with increased specificity constants for collagenases and tumor necrosis factor converting enzyme. Analytical Biochemistry, 328 (2). pp. 166-173. ISSN 0003-2697
Nunn, Caroline, Cervia, Davide, Langenegger, Daniel, Tenaillon, Laurent, Bouhelal, Rochdi and Hoyer, Daniel (2004) Comparison of functional profiles at human recombinant somatostatin sst2 receptor: simultaneous determination of intracellular Ca2+ and luciferase expression in CHO-K1 cells. British Journal of Pharmacology, 142 (1). pp. 150-160. ISSN 0007-1188
Nussbaumer, Peter and Billich, Andreas (2004) Steroid sulfatase inhibitors. Medicinal Research Reviews, 24 (4). pp. 529-576. ISSN 0198-6325
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Orth, Anthony, Batalov, Sergei, Perrone, Mark and Chanda, Sumit (2004) The promise of genomics to identify novel therapeutic targets. Expert Opinion on Therapeutic Targets, 8 (6). pp. 587-596. ISSN 1744-7631
Ostermann, Nils, Gerhartz, Bernd, Worpenberg-Pietruk, Susanne, Trappe, Joerg and Eder, Joerg (2004) Crystal structure of an activation intermediate of cathepsin E. Journal of Molecular Biology, 342 (3). pp. 889-899. ISSN 0022-2836
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Parker, Christian and Schreyer, Suzanne (2004) Application of chemoinformatics to high-throughput screening: practical considerations. Methods in Molecular Biology, 275. pp. 85-110. ISSN 1064-3745
Pearson, Mark Andrew and Fabbro, Doriano (2004) Targeting protein kinases in cancer therapy: a success? Expert Review of Anticancer Therapy, 4 (6). pp. 1113-1124. ISSN 1744-8328
Peters, Eric, Brock, Ansgar and Ficarro, Scott (2004) Exploring the phosphoproteome with mass spectrometry. Mini Reviews in Medicinal Chemistry, 4 (3). pp. 313-324. ISSN 1389-5575
Pletcher, Mathew, Mcclurg, Phillip, Batalov, Sergei, Su, Andrew, Barnes, Whitney, Lagler, Erica, Korstanje, Ron, Wang, Xiaosong, Nusskern, Deborah, Bogue, Molly, Mural, Richard, Paigen, Beverly and Wiltshire, Timothy (2004) Use of a dense single nucleotide polymorphism map for in silico mapping in the mouse. PLoS biology, 2 (12). e393. ISSN 1545-7885
Pletcher, Mathew and Wiltshire, Timothy (2004) Can we find the genes involved in complex traits? Genome Biology, 5 (10). p. 347. ISSN 1465-6914
Prashad, Mahavir, Lu, Yansong and Repic, Oljan (2004) A novel two-carbon homologation with N-vinylacetamides and ethyl vinyl ether as acetaldehyde anion equivalents in the synthesis of 9H-xanthene, 9H-thioxanthene, and 9,10-dihydro-9-acridine carboxaldehydes. The Journal of Organic Chemistry, 69 (2). pp. 584-586. ISSN 0022-3263
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Rausch, Martin, Hiestand, Peter, Foster, Carolyn-Ann, Baumann, Diana, Cannet, Catherine and Rudin, Markus (2004) Predictability of FTY720 efficacy in experimental autoimmune encephalomyelitis by in vivo macrophage tracking: clinical implications for ultrasmall superparamagnetic iron oxide-enhanced magnetic resonance imaging. Journal of Magnetic Resonance Imaging : JMRI, 20 (1). pp. 16-24. ISSN 1053-1807
Ren, Yan-Guo, Wagner, Klaus, Knee, Deborah, Aza-Blanc, Pedro, Nasoff, Marc and Deveraux, Quinn (2004) Differential regulation of the TRAIL death receptors DR4 and DR5 by the signal recognition particle. Molecular Biology of the Cell, 15 (11). pp. 5064-5074. ISSN 1059-1524
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