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Targeting protein kinases in cancer therapy: a success?

Pearson, Mark Andrew and Fabbro, Doriano (2004) Targeting protein kinases in cancer therapy: a success? Expert Review of Anticancer Therapy, 4 (6). pp. 1113-1124. ISSN 1744-8328


The fundamental role of kinases in cancer progression has promoted the development of a plethora of therapeutic inhibitors. Despite the promise of effective treatment with little associated toxicity, the clinical experience with these agents has been mixed. This review will summarize recent advances made in the development of kinase inhibitors to highlight emerging issues and the strategies by which they being addressed.

Item Type: Article
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Additional Information: author can archive post-print (ie final draft post-refereeing); 12 months for institutional or subject based servers
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Date Deposited: 14 Dec 2009 13:55
Last Modified: 31 Jan 2013 01:09


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