A facile synthesis of C2,N3-disubstituted-4-quinazolone.
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Xue, Song, McKenna, Joseph, Shieh, Wen-Chung and Repic, Oljan (2004) A facile synthesis of C2,N3-disubstituted-4-quinazolone. The Journal of Organic Chemistry, 69 (19). pp. 6474-6477. ISSN 0022-3263
Official URL: http://pubs.acs.org/doi/abs/10.1021/jo049118e
Abstract
A simple and efficient methodology for the synthesis of C(2),N(3)-disubstituted-4 quinazolones from anilines and N-acylanthranilic acids was developed. The new cyclization conditions are much milder than any other reported protocols and resulted in excellent yields (87-98%) without chromatography.
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| Date Deposited: | 14 Dec 2009 14:07 |
| Last Modified: | 14 Dec 2009 14:07 |
| URI: | https://oak.novartis.com/id/eprint/43 |