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A facile synthesis of C2,N3-disubstituted-4-quinazolone.

Xue, Song, McKenna, Joseph, Shieh, Wen-Chung and Repic, Oljan (2004) A facile synthesis of C2,N3-disubstituted-4-quinazolone. The Journal of Organic Chemistry, 69 (19). pp. 6474-6477. ISSN 0022-3263


A simple and efficient methodology for the synthesis of C(2),N(3)-disubstituted-4 quinazolones from anilines and N-acylanthranilic acids was developed. The new cyclization conditions are much milder than any other reported protocols and resulted in excellent yields (87-98%) without chromatography.

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Date Deposited: 14 Dec 2009 14:07
Last Modified: 14 Dec 2009 14:07


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