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Items where Year is 2022

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Number of items: 309.

Abdallah, Nasri (2022) People of TM: Video of Nasri Abdallah. YouTube.

Adachi, Yuichiro, Fu, Fumin, Pietropaolo, Michael, Pandit, Shilpa, Li, Weiyan, Murakami, Yutaka, Grewal, Pam, Lussier, Jen, Deyneko, Galina, Turner, Gordon, Shetty, Suraj, Tarnavski, Oleg, Liu, Jing, Cui, Lei, Taggart, Andrew, Waters, Gerry and Coughlin, Shaun (2022) Lack of authentic atrial fibrillation in commonly used murine atrial fibrillation models. PloS one, 17 (1). e0256512. ISSN 1932-6203

Ahire, Deepak, Patel, Mitesh, Deshmukh, Sujal and Prasad, Bhagwat (2022) Quantification of accurate compositions and total abundance of homologous proteins in human tissues using conserved-plus-surrogate peptide (CPSP) approach: Application in the quantification of UDP glucuronosyltransferases. Drug metabolism and disposition. ISSN 1521-009X

Ahmed Madny, Muzaffaruddin, Deshpande, Pandurang, Tumuluri, Sri Venkata, Borde, Parag Prakash and Sangana, Ramachandra (2022) Utilization of in silico tools to investigate the in vivo performance of vildagliptin modified release (MR) 100 mg tablets in healthy subjects using physiologically based biopharmaceutics modeling (PBBM) and evaluate an approach to establish clinically relevant dissolution specifications. AAPS PharmSciTech, 23 (108). pp. 1-17. ISSN 1530-9932

Allmendinger, Thomas, Furet, Pascal, Denay, Regis, Kotoni, Dorina, Bixel, Dominique and Anokwah, Daniel K. (2022) 9-epi-Artemisinin - How a single stereo center affects chemical reactivity and activity. Helvetica Chimica Acta. ISSN 0018-019X1522-2675

Argikar, Upendra, Bednarczyk, Dallas, Cho, Young, Dore, Michael, Jenn, Dumouchel, Ho, Samuel, Hoegenauer, Klemens, Kawanami, Toshio, Mathieu, Simon, Erik, Meredith, Moebitz, Henrik, Stephen, Murphy, Parthasarathy, Van, Pissot Soldermann, Carole, Santos, Jobette, Serena, Silver, Skolnik, Suzanne, Stojanovic, Aleksandar, Chen, Zhuoliang and Blatter, Markus (2022) Paradoxical Increase of Permeability and Lipophilicity with the Increasing Topological Polar Surface Area within a Series of PRMT5 Inhibitors. Journal of medicinal chemistry. ISSN 1520-4804

Auberson, Yves, Lièvre, Akane, Desrayaud, Sandrine and Briard, Emmanuelle (2022) A practical approach to the optimization of positron emission tomography imaging agents for the central nervous system. Journal of labelled compounds & radiopharmaceuticals, 65 (13). pp. 343-350. ISSN 1099-1344

Axelsson, Gisli Thor, Gudmundsson, Gunnar, Aspelund, Thor, Putman, Rachel, Gudmundsson, Elias F, Hatabu, Hiroto, Gudmundsdottir, Valborg, Gudjonsson, Alexander, Launer, Lenore J, Jennings, Lori, Hunninghake, Gary M, Emilsson, Valur and Gudnason, Vilmundur (2022) The Proteomic Profile of Interstitial Lung Abnormalities. American journal of respiratory and critical care medicine. ISSN 1535-4970

Badaoui, Magd , Buigues, Pedro J., Berta, Dénes , Mandana, Gaurav M., Kato, Mitsunori, Dickson, Callum, Hornak, Viktor, Molteni, Carla , Parsons, Simon D. and Rosta, Edina (2022) Combined Free-Energy Calculation and Machine Learning Methods for Understanding Ligand Unbinding Kinetics. Journal of chemical theory and computation. ISSN 1549-9626

Badee, Justine Marine (2022) Current Practices, Gap Analysis and Proposed Roadmaps for PBPK Modeling of Cytochrome P450 Induction: An Industry Perspective. CPT: pharmacometrics & systems pharmacology..

Barabas, Amanda J, Darbyshire, Amanda K, Schlegel, Sylvia L and Gaskill, Brianna N (2022) Evaluation of Ambient Sound, Vibration, and Light in Rodent Housing Rooms. Journal of the American Association for Laboratory Animal Science. ISSN 1559-6109

Barabas, Amanda J, Darbyshire, Amanda K, Schlegel, Sylvia L and Gaskill, Brianna N (2022) Evaluation of Ambient Sound, Vibration, and Light in Rodent Housing Rooms. Journal of the American Association for Laboratory Animal Science, 61 (6). pp. 660-671. ISSN 1559-6109

Barabas, Amanda J., Aryal, Uma K. and Gaskill, Brianna N. (2022) Protein profiles from used nesting material, saliva, and urine correspond with social behavior in group housed male mice, Mus musculus. Journal of Proteomics, 266. p. 104685. ISSN 18743919

Barabas, Amanda J., Robbins, Lindsey A. and Gaskill, Brianna N. (2022) Home cage measures of Alzheimer's disease in the rTg4510 mouse model. Genes, Brain and Behavior, 21 (2). ISSN 1601-1848

Barbosa, Ines, Gopalakrishnan, Rajaraman, Mercan, Samuele, Mourikis, Thanos, Martin, Typhaine, Wengert, Simon, Sheng, Caibin, Ji, Fei, Lopes, Rui, Knehr, Judith, Altorfer, Marc, Lindeman, Alicia, Russ, Carsten, Naumann, Ulrike, Golji, Javad, Sprouffske, Kathleen, Barys, Louise, Schmelzle, Tobias and Galli, Giorgio (2022) Large-scale functional epigenomic screens reveal cancer lineage-specific regulation of YAP responsive elements. Nature Communications.

Bassand, C, Benabed, L, Charlon, S, Verin, J, Freitag, J, Siepmann, F, Soulestin, J and Siepmann, J (2022) 3D printed PLGA implants: APF DDM vs. FDM. Journal of controlled release : official journal of the Controlled Release Society. ISSN 1873-4995

Bassand, C., Benabed, L., Freitag, J., Verin, J., Siepmann, F. and Siepmann, J. (2022) How bulk fluid renewal can affect in vitro drug release from PLGA implants: Importance of the experimental set-up. International Journal of Pharmaceutics: X, 4. pp. 50-60. ISSN 25901567

Bassand, C., Benabed, L., Verin, J., Danede, F., Lefol, L.A., Willart, J.F., Siepmann, F. and Siepmann, J. (2022) Hot melt extruded PLGA implants loaded with ibuprofen: How heat exposure alters the physical drug state. Journal of drug delivery science and technology., 73. ISSN 17732247

Bassand, C., Freitag, J., Benabed, L., Verin, J., Siepmann, F. and Siepmann, J. (2022) PLGA implants for controlled drug release: Impact of the diameter. European Journal of Pharmaceutics and Biopharmaceutics, 177. pp. 50-60. ISSN 09396411

Bassand, Celine, Villois, Alessia, Gianola, Lucas, Laue, Grit, Ramazani, Farshad, Riebesehl, Bernd, Sanchez-Felix, Manuel, Ullrich, Thomas, Sedo, Kurt and Duvnjak Romic, Marieta (2022) Smart design of patient centric long-acting products: from preclinical to marketed pipeline trends and opportunities. Expert opinion on drug delivery. ISSN 1744-7593

Bassand, Celine, Verin, Jeremy, Lamatsch, Martin, Siepmann, Florence and Siepmann, Juergen (2022) How agarose gels surrounding PLGA implants limit swelling and slow down drug release. Journal of controlled release : official journal of the Controlled Release Society, 343. pp. 255-266. ISSN 1873-4995

Beauvois, Hugo (2022) Intership report Hugo Beauvois. Thesis submitted at school (Lycée Lavoisier MULHOUSE).

Bechtold-Peters, Karoline, Gervais, Annick, Dirksen, Eef, Lennart, Andrew, Yi, Linda, Burkitt, Will, Cao, Li, D'Alessio, Valerio, Greven, Simone, Lössner, Christopher, Niu, Ben, O'Riordan, Tomas, Reusch, Dietmar, Shearer, Justin, Spencer, David and Xu, Wei (2022) Use of Multi Attribute Method by mass spectrometry as a QC release and stability tool for biopharmaceuticals – Regulatory Considerations. published on EFPIA homepage (see, N/A (N/A). N/A. ISSN N/A

Bechtold-Peters, Karoline, Wuchner, Klaus, Yi, Linda, Chery, Cyrille, Junge, Friederike, Crotts, George, Rinaldi, Gianluca, Starkey, Jason, Shumann, Melissa, Leiss, Michael, Jahn, Michael, Garidel, Patrick, De Ruiter, Rien, Richer, Sarah, Cao, Shawn, Peuker, Sebastian, Huille, Sylvain, Wang, Tingting and Le Brun, Virginie (2022) Industry Perspective on the Use and Characterization of Polysorbates for Biopharmaceutical Products Part 2: Survey Report on Control Strategy Preparing for the Future. Journal of pharmaceutical sciences, 111 (11). pp. 2955-2967. ISSN 1520-6017

Bechtold-Peters, Karoline (2022) Industry Perspective on the use and Characterization of Polysorbates for Biopharmaceutical Products Part 1: Survey Report on Current State and Common Practices for Handling and Control of Polysorbates. Journal of pharmaceutical sciences, 111 (5). pp. 1280-1291. ISSN 00223549

Bechtold-Peters, Karoline, Paboojian, Stephen and Weikart, Christopher (2022) Improved Drug Stability Stored in Lubricant-Free Hybrid Syringes. American pharmaceutical review, 25 (4 (May). ISSN 10998012

Beckers, Maximilian, Fechner, Nikolas and Stiefl, Nikolaus (2022) 25 Years of Small-Molecule Optimization at Novartis: A Retrospective Analysis of Chemical Series Evolution. Journal of chemical information and modeling, 62 (23). pp. 6002-6021. ISSN 1549-960X

Beckers, Maximilian, Fechner, Nikolas and Stiefl, Nikolaus (2022) Cover art to "25 years of small molecule optimization at Novartis: A retrospective analysis of chemical series evolution". Journal of chemical information and modeling, 62 (23). pp. 5849-6286.

Beckmann, Nicolau (2022) Editorial for "Impact of Dynamic Contrast Enhanced and Diffusion-Weighted MR Imaging on Detection of Early Local Recurrence of Soft Tissue Sarcoma”. Journal of magnetic resonance imaging, 57 (2). pp. 631-632. ISSN doi: 10.1002/jmri.28295

Beckmann, Nicolau (2022) Editorial for "Evaluation of Dynamic Contrast-Enhanced MRI Measures of Lung Congestion and Endothelial Permeability in Heart Failure: A Prospective Method Validation Study”. Journal of Magnetic Resonance Imaging. ISSN 1053-18071522-2586

Benito-Villalvilla, Cristina, de la Rocha-Munoz, Andres, Lopez-Abente, Jacobo, Eggel, Alexander, Bottoli, Ivan, Severin, Thomas, Woisetschlaeger, Maximilian and Palomares, Oscar (2022) Ligelizumab impairs IgE-binding to plasmacytoid dendritic cells more potently than omalizumab and restores IFN-α production and FOXP3+ Treg generation. Allergy. ISSN 1398-9995

Berghausen, Joerg, Petersson, Carl, Zhou, Xin, Cebrian, Brian, Davies, Michael, DeMent, Kevin, Eddershaw, Peter, Emami Riedmaier, Arian, Leblanc, Alix, Manveski, Nenad, Marathe, Punit, Mavroudis, Panteleimon, McDougall, Robin, Parrott, Neil, Reichel, Andreas, Rotter, Charles, Tess, David, Volak, Laurie, Xiao, Guangqing, Yang, Zhen and Baker, James (2022) Current approaches for predicting human PK for small molecule development candidates: Findings from the IQ Human PK Prediction Working Group Survey. The AAPS journal.

Betschart, Claudia, Faller, Michael, Zink, Florence, Hemmig, Rene, Blank, Jutta, Vangrevelinghe, Eric, Bourrel, Marjorie, Glatthar, Ralf, Behnke, Dirk, Barker, Kerstin, Heizmann, Andreas, Angst, Daniela, Nimsgern, Pierre, Jacquier, Sebastien, Junt, Tobias, Collignon Zipfel, Geraldine, Ruzzante, Giulia, Loetscher, Pius, Limonta, Sarah, Hawtin, Stuart, Andre, Cedric Bernard, Boulay, Thomas, Feifel, Roland and Knoepfel, Thomas (2022) Structure-based optimization of a fragment like TLR8 binding screening hit to an in vivo efficacious TLR7/8 antagonist. ACS Medicinal Chemistry Letters. ISSN 1948-58751948-5875

Bluemel, Oliver, Friess, Wolfgang, Rodrigues, Miguel, Geraldes, Vitor, Pavlišič, Andraž, Likozar, Blaž and Bechtold-Peters, Karoline (2022) Computational fluid dynamic simulations of temperature, cryoconcentration, and stress time during large-scale freezing and thawing of monoclonal antibody solutions. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 177. pp. 107-112. ISSN 1873-3441

Bluemel, Oliver, Bechtold-Peters, Karoline, Anuschek, Moritz, Buecheler, Jakob, Hoelzl, Georg and Friess, Wolfgang (2022) The effect of mAb and excipient cryoconcentration on long-term frozen storage stability - Part 1: Higher molecular weight species and subvisible particle formation. International journal of pharmaceutics: X, 4. p. 100108. ISSN 2590-1567

Bluemel, Oliver, Buecheler, Jakob, Hauptmann, Astrid, Hoelzl, Georg, Bechtold-Peters, Karoline and Friess, Wolfgang (2022) The effect of mAb and excipient cryoconcentration on long-term frozen storage stability - part 2: Aggregate formation and oxidation. International journal of pharmaceutics: X, 4. p. 100109. ISSN 2590-1567

Bluemel, Oliver, Friess, Wolfgang, Rodrigues, Miguel, Geraldes, Vitor, Bechtold-Peters, Karoline, Buecheler, Jakob, Hauptmann, Astrid and Hoelzl, Georg (2022) Evaluation of Two Novel Scale-Down Devices for Testing Monoclonal Antibody Aggregation During Large-Scale Freezing. Journal of pharmaceutical sciences. ISSN 1520-6017

Blume, T, Filser, SS, Sgobo, C, Peters, F, Neumann, Ulf, Shimshek, Derya, Saito, T, Saido, T, Brendel, M and Herms, J (2022) β‐secretase inhibition prevents structural spine plasticity deficits in App NL-G-F mice. Frontiers in aging neuroscience., 14. ISSN 1663-4365

Boesch, Julian, Pierrel, Eliane, Lambert, Christian, Doelemeyer, Arno, Kreider, Julie, Accart Gris, Nathalie and Summermatter, Serge (2022) Chemokine-like receptor 1 plays a critical role in modulating the regenerative and contractile properties of muscle tissue. Frontiers in physiology, 13. p. 1044488. ISSN 1664-042X

Bolon, Brad, Francke, Sabine, Caverly Rae, Jessica M., Polack, Evelyne, Regan, Karen S., McInnes, Elizabeth F., Romeike, Annette, Young, Jamie K., Colman, Karyn, Keane, Kevin, Perry, Rick, Jensen, Karl, Nakano-Ito, Kyoko and Galbreath, Elizabeth J. (2022) Scientific and Regulatory Policy Committee Best Practices: Recommended ("Best") Practices for Informed (Non-blinded) Versus Masked (Blinded) Microscopic Evaluation in Animal Toxicity Studies. Toxicologic pathology, 50 (8). pp. 930-941. ISSN 1533-1601

Bondeson, Daniel, Tothova, Zuzana, Golub, Todd, Sellers, William and Ianari, Alessandra (2022) Systematic profiling of conditional degron tag technologies for target validation studies. Nature communications, 13 (1). p. 5495. ISSN 2041-1723

Bonhoeffer, Bastian, Kordikowski, Andreas, John, Edgar and Juhnke, Michael (2022) Numerical modelling of the dissolution of drug nanocrystals and its application to industrial product development. ADMET and DMPK. ISSN 1848-7718

Borsari, Chiara, Matagne, Brieuc, Goncharenko, Kristina, Moreira, Rui and Auberson, Yves (2022) The Facets of Diversity: The EFMC Perspective. ChemMedChem. e202200245. ISSN 1860-7187

Boulton, Craig (2022) People of TM: Video of Craig Boulton. LinkedIn & Youtube.

Bower, Nancy, Achanzar, William E., Boulifard, Virginie, Brink, Peter R., Kittel, Birgit and Vahle, John L. (2022) The Dog as a Second Species for Toxicology Testing Provides Value to Drug Development. International journal of toxicology. p. 10915818221125670. ISSN 1092-874X

Bowman, Christopher, Barrow, Paul, Erkman, Linda and Muller, Mireille (2022) Science-based approach to harmonize contraception recommendations in clinical trials and pharmaceutical labels. Clinical pharmacology and therapeutics. ISSN 1532-6535

Bray, Mark, Durand, Eric, de Weck, Antoine, Fang, Jian, Gabriel, Daniela, Janssens, Rens, Moutsatsos, Ioannis, Spiegel, Stephan and Zhang, Xian (2022) High-content cellular screen image analysis benchmark study. bioRxiv.

Bray, Mark, Durand, Eric, de Weck, Antoine, Fang, Jian, Gabriel, Daniela, Janssens, Rens, Moutsatsos, Ioannis, Spiegel, Stephan and Zhang, Xian (2022) High-content cellular screen image analysis benchmark study. bioRxiv.

Breustedt, Daniel (2022) Interpharma-Interview on surplus animals in transgenics breeding. Interpharma 3R report, n.a. (n.a.). n.a.-n.a.. ISSN n.a.

Brosig, Sebastian, Buecheler, Jakob, Chou, Danny, Christian, Twinkle, Das, Tapan, De Jong, Isabella, Fast, Jonas, Jagannathan, Bharat, Medina, Annette, Moussa, Ehab, Prajapati, Indira, Radwick, Allison and Singh, Shubhadra (2022) End-to-End Approach to Surfactant Selection, Risk Mitigation, and Control Strategies for Protein-Based Therapeutics. The AAPS journal, 25 (1). p. 6. ISSN 1550-7416

Bruin, Gerardus and Walles, Markus (2022) Absorption, Distribution, Metabolism, and Excretion (ADME) of Therapeutic Proteins: A White Paper on Current Industry Practices and Future Perspectives. Drug metabolism and disposition. ISSN doi: 10.1124/dmd.121.000461

Buller, Rebecca, Snajdrova, Radka and Moore, Charles (2022) Bioinformatic Toolbox for the Development of novel CH-Activation Biocatalysts (CH-Pred). Innosuisse Grant Submission.

Bunc, Marko, Boncina, Matjaz, Graf, Christian, Hadži , San and Lah, Jurij (2022) Aggregation Time Machine: A Platform for the Prediction and Optimization of Long-Term Antibody Stability Using Short-Term Kinetic Analysis. Journal of Medicinal Chemistry, 65 (3). pp. 2623-2632. ISSN 0022-26231520-4804

Byrd, Christopher J, McConn, Betty R, Gaskill, Brianna N, Schinckel, Allan P, Green-Miller, Angela R, Lay, Donald C and Johnson, Jay S (2022) Characterizing the effect of incrementally increasing dry bulb temperature on linear and nonlinear measures of heart rate variability in nonpregnant, mid-gestation, and late-gestation sows. Journal of Animal Science, 100 (1). ISSN 0021-8812

Böttinger, Katharina, Paul, Katrin, Esser-Skala, Wolfgang, Segl, Marius, Herwig, Christoph and Huber, Christian (2022) At-line quantitative profiling of monoclonal antibody products during bioprocessing using HPLC-MS. Analytica chimica acta, 1207. p. 339813. ISSN 1873-4324

Calonder, Claudio, Lotz, Gregor, Benstein, Karin, Bloem, Karien, Buddinger, Harm, Elm, Stefanie, Fernandez, Elena, Gorovits, Boris, Grudzinska-Goebel, Joanna, Janssen, Melody, Jawa, Vibha, Luo, LinLin, Malisauskas, Mantas, Michaut, Lydia, Schäfer, Martin, Spindeldreher, Sebastian, Ullmann, Martin, Weldingh, Karin Nana, Kromminga, Arno, Snoeck, Veerle, Kramer, Daniel and Joanne, Goodman (2022) When to Extend Monitoring of Anti-drug Antibodies for High-risk Biotherapeutics in Clinical Trials: an Opinion from the European Immunogenicity Platform. The AAPS journal, 24 (3). p. 68. ISSN 1550-7416

Casado-García, Ana, Isidro-Hernández, Marta , Oak, Ninad, Mayado, Andrea , Mann-Ran, Christine, Raboso-Gallego, Javier , Alemán-Artega, Silvia , Buhles, Alexandra, Sterker, Dario, Blanco, Oscar, Orfao, Alberto, Alonso-López, Diego, De Las Rivas, Javier, Riesco, Susana, Prieto-Matos, Pablo, Criado, Francisco Javier García, Cenador, María Begoña García, Radimerski, Thomas, Ramírez-Orellana, Manuel, Cobaleda, César, Yang, Jun J, Vicente-Dueñas, Carolina, Weiss, Andreas, Nichols, Kim E and Sánchez-García, Isidro (2022) Transient JAK/STAT pathway inhibition prevents natural occurring B-ALL development in genetically predisposed Pax5+/- mice. Cancer research, Epub a (canres). ISSN 1538-7445; 0008-5472

Chan, Jason, Allen, Richard, Boras, Britton, Cabal, Antonio, Damian, Valeriu, Gibbons, Francis, Gulati, Abhishek, Hosseini, Iraj, Kearns, Jeff, Ryuuta, Saitou, Cucurull-Sanchez, Lourdes, Selimkhanov, Jangir, Stein, Andrew, Umehara, Kenichi, Wang, Guanyu, Wang, Weirong and Neves-Zaph, Susana (2022) Current practices for QSP model assessment: an IQ consortium survey. Journal of pharmacokinetics and pharmacodynamics. ISSN 1573-8744

Charmont, Stephane, Sangana, Ramachandra and Valentin, Marie-Anne (2022) Development, validation and application of a liquid chromatography-tandem mass spectrometry method for the activity and inhibition of DPP-4. Bioanalysis, 14 (6). pp. 369-378. ISSN 1757-6199

Chen, Jin, Gu, Jessie, Shah, Bharti, Stringer, Rowan, Reis da Silva Torrao, Leonel, Hackling, Melissa, Nidamarthy, Prasanna, Prince, William and Woessner, Ralph (2022) Pharmacokinetics of Tropifexor, a Potent Farnesoid X Receptor Agonist, in Participants With Varying Degrees of Hepatic Impairment. Journal of clinical pharmacology, 62 (4). pp. 520-531. ISSN 1552-4604

Clark, Kirk, Kulathila, Raviraj, Wright, Kirk, Isome, Yuko, Sage, David, Yang, Yi and Christodoulou, Constantina (2022) Crystal structure of 2-PG bound to BPGM. RCSB Protein Data Bank.

Clarke, Adrian and Stoll, Dwight (2022) Analytically-speaking-podcast podcast "sometimes negative results turn out to be the most interesting ones": Adrian Clarke interviewed by Dwight Stoll. LC-GC europe : Solutions for Separation Scientists..

Combes, Francois Pierre, Li, Ying fei, Hoch, Matthias, Lorenzo, Sebastien, Ho, Yu-Yun and Sy, Sherwin (2022) Exposure-Efficacy Analysis of Asciminib in Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase. Clinical pharmacology and therapeutics, 112 (5). pp. 1040-1050. ISSN 1532-6535

Connelly, Kim A, Wu, Ellen, Visram, Aylin, Friedberg, Mark K, Batchu, Sri Nagarjun, Yerra, Veera Ganesh, Thai, Kerri, Nghiem, Linda, Zhang, Yanling, Kabir, Golam, Desjardins, J F, Advani, Andrew and Gilbert, Richard E (2022) The SGLT2i dapagliflozin reduces RV mass independent of changes in RV pressure induced by pulmonary artery banding. Cardiovascular drugs and therapy. ISSN 1573-7241

Cortopassi, Wilian A., Gunderson, Emma, Annunciato, Yasmin, Silva, Antony.E.S., dos Santos Ferreira, Amália, Garcia Teles, Carolina Bioni, Pimentel, Andre S., Ramamoorthi, Roopa, Gazarini, Marcos, Meneghetti, Mario R., Guido, Rafael.V.C., Pereira, Dhelio B., Jacobson, Matthew P., Krettli, Antoniana U. and Caroline C Aguiar, Anna (2022) Fighting Plasmodium chloroquine resistance with acetylenic chloroquine analogues. International Journal for Parasitology: Drugs and Drug Resistance. ISSN 22113207

Crowley, Maura, Garland, Donita, Sellner, Holger, Banks, Angela, Rejtar, Tomas, Buchanan, Natasha, Delgado, Omar, Xu, YongYao, Adams, Christopher, Mogi, Muneto, Bigelow, Chad, Poor, Stephen, Anderson, Karen, Jaffee, Bruce, Prasanna, Ganesh, Grosskreutz, Cyndy, Feenandez-Godino, Rosario, Pierce, Eric, Dryja, Thaddeus and Liao, Sha-Mei (2022) Complement factor B is critical for sub-RPE deposit formation in a model of DHRD/ML with features of age-related macular degeneration. Human molecular genetics.

Cvetkoska, Aleksandra, Dermol-Cerne, Janja, Miklavčič, Damijan, Kranjc Brezar, Simona, Markelc, Boštjan, Serša, Gregor and Reberšek, Matej (2022) Design, Development, and Testing of a Device for Gene Electrotransfer to Skin Cells In Vivo. Pharmaceutics, 14 (9). p. 1826. ISSN 1999-4923

Dalvit, Claudio, Veronesi, Marina and Vulpetti, Anna (2022) 1H and 19F NMR chemical shifts for hydrogen bond strength determination: Correlations between experimental and computed values. Journal of Magnetic Resonance Open, 12-13. ISSN 26664410


Davis, Haley J., Barabas, Amanda J. and Gaskill, Brianna N. (2022) Titrating the preferences of altered lighting against temperature in female CD-1 laboratory mice, Mus musculus. Applied Animal Behaviour Science, 246. p. 105541. ISSN 01681591

Davis, John, Kulmatycki, Ken, Humphries, Sara C, Iqbal, Sajida, Kamel, Amin, Lao, Yanbin, Liu, Xiumin, Rogers , John, Snoeys, Jan, Weng, Yan, Vigil, Adam, Wiethoft, Christopher M and Wittwer, Matthias B (2022) Considerations and recommendations for assessment of plasma protein binding and drug-drug interactions for siRNA therapeutics. Nucleic acids research, 50 (11). pp. 6020-6037.

Dawson King, Janet, Accart Gris, Nathalie, Obrecht, Michael, Lambert, Christian, Flueckiger, Manuela, Kreider, Julie, Hatakeyama, Shinji, Richards, Peter and Beckmann, Nicolau (2022) Degenerative joint disease induced by repeated intra-articular injections of monosodium urate crystals in rats as investigated by translational imaging. Scientific reports, 12 (1). p. 157. ISSN 2045-2322

De Luca, Valeria (2022) People of TM: Video of Valeria de Luca. LinkedIn & YouTube.

De Luca, Valeria (2022) Measuring Health-Related Quality of Life With Multimodal Data: Viewpoint. Journal of medical internet research, 24 (5). ISSN 1438-8871

Demanse, David, Saxer, Franziska, Lustenberger, Patrick, Tanko, Laszlo, Nikolaus, Philipp, Rasin, Ilja, Brennan, Damian, Roubenoff, Ronenn, Premji, Sumehra, Conaghan, Philip and Schieker, Matthias (2022) Unsupervised machine-learning algorithms for the identification of clinical phenotypes in the osteoarthritis initiative database. Seminars in arthritis and rheumatism, 58. p. 152140. ISSN 1532-866X

Devaraj, Sankarganesh, Barabas, Amanda J., Soini, Helena A., Novotny, Milos V., Lucas, Jeffrey R., Erasmus, Marisa A., Cheng, Heng-Wei, Palme, Rupert and Gaskill, Brianna N. (2022) Assessing the effect of compounds from plantar foot sweat, nesting material, and urine on social behavior in male mice, Mus musculus. PLOS ONE, 17 (11). e0276844. ISSN 1932-6203

Dhandapani, Rahul, Neri, Marilisa, Bernhard, Mario, Brzak, Irena, Schweizer, Tatjana, Rudin, Stefan, Stefanie, Joller, Berth, Ramon, Kernen, Jasmin, Neuhaus, Anna, Waldt, Annick, Cuttat-Theurillat, Rachel, Naumann, Ulrike, Gubser Keller, Caroline, Roma, Guglielmo, Feuerbach, Dominik, Shimshek, Derya, Ulf, Neumann, Gasparini, Fabrizio and Galimberti, Ivan (2022) Sustained Trem2 stabilization accelerates microglia heterogeneity and Aβ pathology in a mouse model of Alzheimer’s disease. Cell reports, 39 (9). ISSN 2211-1247

DiDominick, Sarah, Abozeid, Ahmed M, Chen, Xueying, Stammberger, Uz, Santoro, Armando, Su, Wu-Chou, Navarro, Alejandro, Simonelli, Matteo, Yang, James CH, Ardizzoni, Andrea, Barlesi, Fabrice, Kang, Jin Hyoung and Felip, Enriqueta (2022) Phase Ib/II study of ceritinib in combination with ribociclib in patients with ALK-rearranged non-small cell lung cancer. Lung cancer (Amsterdam, Netherlands), 166. pp. 170-177. ISSN 1872-8332

Dickson, Callum, Walker, Ross and Gould, Ian (2022) Lipid21: Complex Lipid Membrane Simulations with AMBER. Journal of chemical theory and computation. ISSN 1549-9626

Dillon, Noah, Cocanougher, Ben, Sood, Chhavi, Yuan, Xin, Kohn, Andrea B, Moroz, Leonid L, Siegrist, Sarah E, Zlatic, Marta and Doe, Chris Q. (2022) Single cell RNA-seq analysis reveals temporally-regulated and quiescence-regulated gene expression in Drosophila larval neuroblasts. Neural Development, 17 (1). ISSN 1749-8104

Dimitrieva Janeva, Slavica, Janssens, Rens, Li, Gang, Szalata, Artur, Gopal, Raja, Parmar, Chintan, Kauffmann, Audrey and Durand, Eric (2022) Biologically relevant integration of transcriptomics profiles from cancer cell lines, patient derived xenografts and patient tumors using deep neural networks. bioRxiv.

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Quackenbush, Doug, Chu, Tiffany, Lo, Frederick, Sutherland, Jeffrey, Kuzu, Guray, Roberts, Chris, Luna, Fabio, Barnes, Whitney, Walker, John and Kuss, Pia (2022) "3D, human renal proximal tubule (RPTEC-TERT1) organoids 'tubuloids' for translatable evaluation of nephrotoxins in high-throughput". PloS one, 17 (11). e0277937. ISSN 1932-6203

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Rawat, Manoj, Natasha , Manners, Vishnu, Priya , Abhishesh Kumar , Mehata and Madaswamy S, Muthu (2022) Theranostic Nanomedicines for the Treatment of Cardiovascular and Related Diseases: Current Strategies and Future Perspectives. Pharmaceuticals, 15 (4). p. 441. ISSN 1424-8247

Reddy, K. Raja , Totrov, Maxim , Lomovskaya, Olga, Griffith, David C. , Tarazi, Ziad , Clifton, Matt and Hecker, Scott J. (2022) Broad-spectrum cyclic boronate β-lactamase inhibitors featuring an intramolecular prodrug for oral bioavailability. Bioorganic & medicinal chemistry, 62. p. 116722. ISSN 1464-3391

Rees, David C, Kilinc, Yurdanur, Unal , Selma, Dampier, Carlton, Pace, Betty S, Kaya, Banu, Trompeter, Sara, Odame , Isaac, Mahlangu, Johnny, Unal, Sule, Brent, Julie, Grosse, Regine, Fuh, Beng R, Inusa, Baba PD, Koren, Ariel, Levin, Carina, McNamara, Elizabeth, Meiser, Karin, Hom, Douglas and Oliver, Stephen (2022) Inhibiting IL-1beta-mediated inflammation in pediatric and young adult patients with sickle cell anemia: a randomized, placebo-controlled, double-blind trial with canakinumab (ACZ885). Blood.

Reeves, Audrey, Christian, Alec, McKenna, Jeffrey, Lewis, Richard, Fang, Eric, Dovala, Dustin, McGregor, Lynn, Schirle, Markus, Tallarico, John, Nomura, Daniel, Toste, Dean and Chang, Christopher (2022) An Activity-Based Oxaziridine Platform for Developing Covalent Ligands Against Functional Allosteric Methionine Sites: Redox-Dependent Inhibition of Cyclin-Dependent Kinase 4. JACS.

Reilly, Dorothy, Alharbi, Ebtisam, Gadiya, Yojana , Henderson, David, Zaliani, Andrea , Delfin-Rossaro, Alejandra , Cambon-Thomsen, Anne , Witt, Gesa , Welter, Danielle , Juty, Nick, Jay, Caroline, Goble, Carol, Satagopam, Venkata , Ioannidis, Vassilios , Gu, Wei and Gribbon, Phil (2022) Selection of datasets for FAIRification in Drug Discovery and Development: Which, Why, and How? Drug discovery today. ISSN 1878-5832

Rodriguez Perez, Raquel, Trunzer, Markus, Schneider, Nadine, Faller, Bernard and Gerebtzoff, Gregori (2022) Multi-species machine learning predictions of in vitro intrinsic clearance with uncertainty quantification analyses. Molecular Pharmaceutics. ISSN 1543-83841543-8392

Rodriguez Perez, Raquel, Miljkovic, Filip and Bajorath, Jürgen (2022) Machine Learning in Chemoinformatics and Medicinal Chemistry. Annual review of biomedical data science. ISSN 2574-3414

Roediger, Ben and Schlapbach, Christoph (2022) T cells in the skin: lymphoma and inflammatory skin disease. The journal of allergy and clinical immunology, 149. pp. 1172-1184. ISSN 1097-6825

Roggo, Yves, Martinez Heredia, Lizbeth, Peinado Amores, Antonio and Matero, Sanni (2022) Near infrared spectroscopy for blend uniformity monitoring: an innovative qualitative application based on the coefficient of determination. Journal of near infrared spectroscopy, 30 (6). pp. 322-336. ISSN 1364-6575; 0967-0335

Ruddy, David, Cremasco, Viviana, Chang, Jonathan, Piquet, Michelle and Ittershagen, Stacie (2022) Harnessing Drivers of Pancreatic Cancer Plasticity for Therapeutic Intent. Figures to be submitted as part of a P01 grant.

Salazar, Mario G, Cervera, Iris P, French, Karen, Garcia-Martin, Ruben, Bluher, Matthias, Schofield, Chris, Chavakis, Trian, Gudmundsson, Elias F, Radcliffe, Peter, Jennings, Lori, Gudnason, Vilmundur, Morton, Nicholas M, Emilsson, Valur and Machailidou, Zoi (2022) Adipocyte-specific deletion of the oxygen-sensor PHD2 sustains elevated energy expenditure at thermoneutrality.

Saldivia Concepcion, Manuel Alejandro (2022) CLK1/CLK2-driven signalling at the Leishmania kinetochore is captured by spatially referenced proximity phosphoproteomics. Communications biology, 5 (1). p. 1305. ISSN 2399-3642

Salian-Mehta, Smita, Poling, Jerry, Birkebak, Joanne, Rensing, Susanne, Carosino, Chris, Santos, Rosemary, West, Wanda, Adams, Khary, Orsted, Kathy, Fillman-Holliday, Denise and Burns, Monika (2022) Non-Human (NHP) husbandry and impact on NHP health: outcomes from a DruSafe/3Rs industrial benchmark survey. International Journal of Toxicology. ISSN 1091-58181092-874X

Salvi, Amrita, Young, Alexandria N., Huntsman, Andrew C., Pergrande, Melissa, Korkmaz, Melissa A., Mize, Brittney K., Zhang, Xiaoli, Ratia, Kiira, Shelton IV, Claude, Brittain, Scott, Schirle, Markus, Thomas, Jason, Aldritch, Leslie N., Cologna, Stephanie M., Fuchs, James R. and Burdette, Joanna E. (2022) PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancer. Cell death & disease, 13 (1). p. 45. ISSN 2041-4889

Saxer, Franziska (2022) People of TM: Video of Franziska Saxer. YouTube.

Schiller, Hilmar, Huth, Felix, Schuhler, Carole, Drollmann, Anton Franz, Kaul, Martin, Woessner, Ralph, Shah, Bharti, Weis, Wendy and End, Peter (2022) Novel Bruton’s tyrosine kinase inhibitor remibrutinib: Assessment of drug-drug interaction potential as a perpetrator of cytochrome P450 enzymes and drug transporters and the impact of covalent binding on possible drug interactions. European journal of pharmaceutical sciences, 172. ISSN 09280987

Schmelzer, Bernhard and Sutter, Marc (2022) Tolerance Interval Approach for the Determination of Overfill of Liquid Parenteral Drug Products. PDA journal of pharmaceutical science and technology, 77 (3). pp. 181-196. ISSN 1948-2124

Schoeberl, Birgit and Kearns, Jeff (2022) Navigating Between Right, Wrong, and Relevant: The Use of Mathematical Modeling in Preclinical Decision Making. Frontiers in pharmacology, 13. p. 860881. ISSN 1663-9812

Schuetz, Stefan, Bergsdorf, Christian, Goretzki, Benedikt, Lingel, Andreas, Renatus, Martin, Gossert, Alvar and Jahnke, Wolfgang (2022) The Disordered MAX N-terminus Modulates DNA Binding of the Transcription Factor MYC:MAX. Journal of molecular biology, 434 (22). p. 167833. ISSN 1089-8638

Schwab, Nathalie, Nienhold, Ronny, Henkel, Maurice, Baschong, Albert, Graber, Anne, Frank, Angela, Mensah, Nadine, Koike, Jacqueline, Hernach, Claudia, Sachs, Melanie, Willi, Niels, Zsikla, Veronika, Junt, Tobias and Mertz, Kirsten (2022) COVID-19 Autopsies Reveal Underreporting of SARS-CoV-2 Infection and Scarcity of Co-infections. Frontiers in medicine, 9. p. 868954. ISSN 2296-858X

Scorrano, Fabrizio (2022) A New Feeder Device to Provide Cleaner and Accessible Diet Gel to Laboratory Mice. Laboratory Animal Science Professional. pp. 50-52.

Scuderi, Maria, Dermol-Cerne, Janja, Amaral da Silva, Clarissa, Muralidharan, Aswin, Boukany, Pouyan E. and Rems, Lea (2022) Models of electroporation and the associated transmembrane molecular transport should be revisited. Bioelectrochemistry, 147. p. 108216. ISSN 15675394

Sechaud, Romain, Sinclair, Karen, Grosch, Kai and Pathak, Dhrubajyoti (2022) Evaluation of drug-drug interactions between midostaurin and strong CYP3A4 inhibitors in patients with FLT-3-mutated acute myeloid leukemia (AML). Cancer chemotherapy and pharmacology, 90 (1). pp. 19-27. ISSN 1432-0843

Seelinger, Felix, Wittkopp, Felix, von Hirschheydt, Thomas and Frech, Christian (2022) Anti-Langmuir elution behavior of a bispecific monoclonal antibody in cation exchange chromatography: Mechanistic modeling using a pH-dependent Self-Association Steric Mass Action isotherm. Journal of chromatography A, 1689 (1689). unknown-unknown. ISSN 1873-3778; 0021-9673

Segal, Florencia (2022) People of TM: Video of Florencia Segal. LinkedIn.

Seror, Raphaele, Baron, Gabriel, Camus, Marine, Cornec, Divi, Perrodeau, Elodie, Bowman, Simon, Bombardieri, Michele, Bootsma, Hendrika, Gottenberg, Jaccques-Eric, Fisher, Benjamin, Hueber, Wolfgang, van Roon, Joel, Devauchelle-Pensec, Valerie, Gergely, Peter, Mariette, Xavier and Porcher, Raphael (2022) Development and preliminary validation of the Sjögren’s Tool for Assessing Response (STAR): a consensual composite score for assessing treatment effect in primary Sjögren’s syndrome. Annals of the rheumatic diseases : ARD, Online (Online). Online-Online. ISSN Online ahead of print

Shabani, Shaban, Bourke, Alan, Muaremi, Amir, O'Keeffe, Kate, Argent, Rob, Caulfield, Brian, Praestgaard, Jens, Scotti, Celeste and Walsh, Lorcan (2022) An Automatic Foot and Shank IMU Synchronization Algorithm: Proof-of-concept. IEEE Engineering in Medicine and Biology Society (EMBC) 2022 Conference.

Shaqra, Ala, Zvornicanin, Sarah, Qiu, Huang, Lockbaum, Gordon, Knapp, Mark, Tandeske, Laura, Barkan, Dave, Flynn, Julia, Bolon, Daniel, Moquin, Stephanie, Dovala, Dustin, Yilmaz, Nese and Schiffer, Celia (2022) Defining the substrate envelope of SARS-CoV-2 main protease to predict and avoid drug resistance. Nature communications, 13 (1). p. 3556. ISSN 2041-1723

Skolnik, Suzanne, Barrett, Jaclyn, Yang, Wenzhan, Belliveau, Lisa and Patros, Kellyn (2022) Discovery solubility measurement and assessment with drug development in mind. Drug discovery today. ISSN 13596446

Slieker, Rocerick C, Donnelly, Louise A, Jennings, Lori, Hart, Leen M, Pearson, Ewan R and Rutter, Guy A (2022) Novel biomarkers for glycaemic deterioration in type 2 diabetes: an IMI RHAPSODY study.

Snyder, Jennifer (2022) We Support each other to Develop and Grow at Novartis. Biopharma Asia / also published in Biopharma Careers .

Spencer, Sarah, Chung, Jessie R., Belongia, Edward A., Sundaram, Maria, Meece, Jennifer, Coleman, Laura A., Zimmerman, Richard K., Nowalk, Mary Patricia, Moehling Geffel, Krissy, Ross, Ted, Carter, Chalise E., Shay, David, Levine, Min, Liepkalns, Justine, Kim, Jin Hyang, Sambhara, Suryaprakash, Thompson, Mark G. and Flannery, Brendan (2022) Impact of diabetes status on immunogenicity of trivalent inactivated influenza vaccine in older adults. Influenza and Other Respiratory Viruses, 16 (3). pp. 562-567. ISSN 1750-2640

Stange, Carolin, Sánchez-Reyes, Gabriela, Graalfs, Heiner and Frech, Christian (2022) Influence of ligand density variations on the two peak elution behavior of a monoclonal antibody in cation exchange chromatography. Journal of Chromatography A, 1680. ISSN 00219673

Statelova, Marina, Vertzoni, Maria and Kourentas, Alexandros (2022) Simulation of intraluminal performance of lipophilic weak bases in fasted healthy adults using the DDDPlusTM Artificial Stomach Duodenum model. The AAPS journal, 24 (5).

Stocker, Stephan, Rogue, Vincent, Steib-Lauer, Caroline, Haecker, Hans-Georg, Spickermann, Dirk, Hirsch, Stefan, Dhareshwar, Sundeep, Claudia, Vicente Martin and Manel, Bautista (2022) Twin-screw melt granulation based high drug load tablet formulation. An industrial perspective on process transfer to a commercial manufacturing site. Drug development and industrial pharmacy, https:. pp. 1-15. ISSN 1520-5762; 0363-9045

Sun, Sophie, Sechidis, Kostas, Chen, Yao, Lu, Jiarui, Ma, Chong, Mirshani, Ardalan, Ohlssen, David, Vandemeulebroecke, Marc and Bornkamp, Bjoern (2022) Comparing algorithms for characterizing treatment effect heterogeneity in randomized trials. Biometrical journal. Biometrische Zeitschrift. ISSN 1521-4036

Sy, Sherwin, Tanaka, Chiaki and Grosch, Kai (2022) Population Pharmacokinetics and Pharmacodynamics of Crizanlizumab in Healthy Subjects and Patients with Sickle Cell Disease. Clinical pharmacokinetics. ISSN 1179-1926

Sykes, David A, Jimenez-Roses, Mireia, Reilly, John, Fairhurst, Robin, Charlton, Steven J and Veprintsev, Dmitry (2022) Exploring the kinetic selectivity of drugs targeting the beta1-adrenoceptor. Molecular pharmacology, 10 (4). pp. 1-14. ISSN 2052-1707

Taskar, Kunal, Yang, Xinning, Neuhoff, Sibylle, Patel, Mitesh, Yoshida, Kenta, Paine, Mary, Brouwer, Kim, Chu, Xiaoyan, Sugiyama, Yuichi, Cook, Jack, Polli, Joseph, Hanna, Imad, Lai, Yurong and Zamek-Gliszczynski, Maciej (2022) Clinical relevance of hepatic and renal P-gp/BCRP inhibition of drugs: An International Transporter Consortium perspective. Clinical pharmacology and therapeutics. ISSN 1532-6535

Tassano, Erika, Moore, Charles, Dussauge, Solene, Vargas, Alexandra and Snajdrova, Radka (2022) Discovery of novel Fe(II)/α-ketoglutarate-dependent dioxygenases for oxidation of L-proline. Organic Process Research & Development. ISSN 1083-61601520-586X

Taubenschmid-Stowers, Jasmin, Krauditsch, Christian, Studer, Christian, Lämmerer, Anna, Lötsch, Daniela, Gojo, Johannes, Widhalm, Georg, Peyrl, Andreas, Spiegl-Kreinecker, Sabine, Berger, Walter, Hoepfner, Dominic, Bian, Shan, Knoblich, Juergen, Elling, Ulrich and Penninger, Josef M. (2022) A whole genome scan for Artemisinin cytotoxicity reveals a novel therapy for human brain cancer. EMBO molecular medicine, e16959 (e16959). pp. 1-20. ISSN 1757-4684; 1757-4676

Tia , Byer and Richter, Susanne (2022) Future Directions for Accelerated Upstream Bioprocessing. Cell Content hub:, n.a. (n.a.). n.a.-n.a.. ISSN n.a.

Tin, Adrienne, Jennings, Lori, Gudnason, Vilmundur and Mosley, Thomas H (2022) Proteomic analysis identifies circulating proteins associated with plasma amyloid βeta and incident dementia. Biological Psychiatry Global Open Science. ISSN 26671743

Tjaden, Amelie, Chaikuad, Apirat, Kowarz, Eric, Marschalek, Rolf, Knapp, Stefan, Schröder, Martin and Müller, Susanne (2022) Image-Based Annotation of Chemogenomic Libraries for Phenotypic Screening. Molecules (Basel, Switzerland), 27 (4). ISSN 1420-3049

Torres, Julia Baguña, Roodselaar, Jay, Sealey, Megan, ziehn, marina, Bigaud, Marc, Kneuer, Rainer, Leppert, David, Weckbecker, Gisbert, Cornelissen, Bart and Anthony, Anthony (2022) Distribution and Efficacy of Ofatumumab and Ocrelizumab in Humanized CD20 Mice Following Subcutaneous or Intravenous Administration. Frontiers in Immunology: Multiple Sclerosis and Neuroimmunology’..

Tsai, Kaitlyn, Stojković, Vanja, Lee, D John, Young, Iris D, Szal, Teresa, Klepacki, Dorota, Vázquez-Laslop, Nora, Mankin, Alexander S, Fraser, James S and Fujimori, Danica Galonić (2022) Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nature structural & molecular biology, 29 (2). pp. 162-171. ISSN 1545-9985

Tsai, Kaitlyn, Stojković, Vanja, Noda-Garcia, Lianet, Young, Iris D, Myasnikov, Alexander G, Kleinman, Jordan, Palla, Ali, Floor, Stephen N, Frost, Adam, Fraser, James S, Tawfik, Dan S and Fujimori, Danica Galonić (2022) Directed evolution of the rRNA methylating enzyme Cfr reveals molecular basis of antibiotic resistance. eLife, 11. ISSN 2050-084X

Tuckwell, Danny (2022) People of TM: Video of Danny Tuckwell. YouTube.

Tukov, Francis, Mansfield, Keith, Milton, Mark, Meseck, Emily, Penraat, Kelley, Hartmann, Andreas and Chand, Deepa (2022) Single-Dose Intrathecal Dorsal Root Ganglia Toxicity of Onasemnogene Abeparvovec in Cynomolgus Monkeys. Human gene therapy. ISSN 1557-7422

Uddin, Erfan Muhammad, Eisenmann, Eric D, Huang, Kevin M, Garrison, Dominique A, Talebi, Zahra, Gibson, Alice A, Jin, Yan, Nepal, Mahesh, Bonilla, Ingrid M, Fu, Qiang, Millar, Alec, Tarasov, Mikhail, Jay, Christopher E, Cui, Xiaoming, Einolf, Heidi, Pelis, Ryan, Smith, Sakima A, Radwanski, Przemyslaw, Sweet, Douglas H, Konig, Jorg, Fromm, Martin F, Carnes, Cynthia A, Hu, Shuiying and Sparreboom, Alex (2022) Contribution of MATE1 to Dofetilide-Induced Proarrhythmia. International journal of molecular sciences, 23. ISSN 1422-0067

Ullrich, Thomas, Teixeira-Fouchard, Sylvie, Broennimann, Valerie, Stiefl, Nikolaus, Head, Victoria, Kramer, Ina, Guth-Gundel, Sabine, Arista, Luca and Weiler, Sven (2022) Discovery of a novel 2-aminopyrazine-3-carboxamide as a potent and selective inhibitor of Activin Receptor-Like Kinase-2 (ALK2) for the treatment of fibrodysplasia ossificans progressiva. Bioorganic & medicinal chemistry letters. ISSN 1464-3405

Ungricht, Rosemarie, Guibbal, Laure, Lasbennes-Eckerlen, Marie-Christine, Orsini, Vanessa, Beibel, Martin, Waldt, Annick, Cuttat-Theurillat, Rachel, Carbone, Walter, Basler, Anne, Roma, Guglielmo, Nigsch, Florian, Tchorz, Jan, Hoepfner, Dominic and Hoppe, Philipp (2022) Genome-wide screening in human kidney organoids identifies novel aspects of nephrogenesis. Cell stem cell, 29 (1). p. 160. ISSN 19345909

Vicart, Axel (2022) People of TM: Video of Axel Vicart. YouTube.

Villois, Alessia, Capasso Palmiero, Umberto, Mathur, Prerit, Perone, Gaia, Schneider, Timo, Li, Lunna, Salvalaglio, Matteo, deMello, Andrew, Stavrakis, Stavros and Arosio, Paolo (2022) Droplet Microfluidics for the Label-Free Extraction of Complete Phase Diagrams and Kinetics of Liquid-Liquid Phase Separation in Finite Volumes. Small (Weinheim an der Bergstrasse, Germany), 18 (46). e2202606. ISSN 1613-6829

Voss, Moritz, Hüppi, Sean, Schaub, Daniela, Hayashi, Takahiro, Ligibel, Mathieu, Sager, Emine, Schroer, Kirsten, Snajdrova, Radka and Buller, Rebecca (2022) Enzyme engineering enables inversion of substrate stereopreference of the halogenase WelO5*. ChemCatChem.. ISSN 1867-3899

Vulin, Milica, Sethi, Atul, Jehanno, Charlie, Obradovic, Milan, Correia, Ana, Pinto Do Couto E Silva, Joana, Auf der Maur, Priska, Schmidt, Alexander, Coissieux, Marie-May, Munst, Simone, Preca, Tiberius, Diepenbruck, Maren, Volkmann, Katrin, Sauteur, Loic, Britschgi, Adrian, Unterreiner, Vincent, Galuba, Olaf, Claerr, Isabelle, Lopez Romero, Sandra, Galli, Giorgio, Baeschlin, Daniel, Okamoto, Ryoko, Soysal, Savas, Mechera, Robert, Weber, Walter, Radimerski, Thomas and Bentires-Alj, Mohamed (2022) A high-throughput drug screen reveals means to differentiate triple-negative breast cancer. Oncogene. ISSN 1476-5594

Vulpetti, Anna, Lingel, Andreas, Dalvit, Claudio, Schiering, Nikolaus, Oberer, Lukas, Henry, Christelle and Lu, Yipin (2022) Efficient Screening of Target-Specific Selected Compounds in Mixtures by 19F NMR Binding Assay with Predicted 19F NMR Chemical Shifts. ChemMedChem : chemistry enabling drug discovery. ISSN 1860-7187; 1860-7179

Walles, Markus (2022) Meeting report of the second European Biotransformation Workshop. Xenobiotica, 52 (4). pp. 426-431.

Walles, Markus (2022) A Cross Company Perspective on the Assessment of Therapeutic Protein Biotransformation. Drug metabolism and disposition, June.

Wargenau, Manfred, Reidemeister, Sibylle, Klingmann, Ingrid and Klingmann , Viviane (2022) A composite endpoint for acceptability evaluation of oral drug formulations in the pediatric population. Therapeutic Innovation & Regulatory Science (TIRS) , 2022.

Weeks, Ryan, Zhou, Xin, Yuan, Tina and Zhang, Jin (2022) Fluorescent Biosensor for Measuring Ras Activity in Living Cells. Journal of the American Chemical Society, 144 (38). pp. 17432-17440. ISSN 1520-5126

Weeks, Ryan, Zhou, Xin, Yuan, Tina and Zhang, Jin (2022) A fluorescent biosensor for measuring Ras activity in living cells. Journal of the American Chemical Society JACS.. ISSN 0002-78631520-5126

Weisberg, Ellen, Chowdhury, Basudev, Meng, Chengcheng, Case, Abigail, Ni, Wei, Garg, Swati, Sattler, Martin, Azab, Abdel Kareem, Sun, Jennifer, Muz, Barbara, Sanchez, Dana, Toure, Anthia, Stone, Richard, Galinsky, Ilene, Winer, Eric, Gleim, Scott, Gkountela, Sofia, Kedves, Alexia, Harrington, Edmund, Abrams, Tinya, Zoller, Thomas, Vaupel, Andrea, Manley, Paul, Faller, Michael, Chung, BoYee, Chen, Xin, Busenhart, Philipp, Stephan, Christine, Calkins, Keith, Bonenfant, Debora, Thoma, Claudio, Forrester, William and Griffin, James (2022) BRD9 degraders as chemosensitizers in acute leukemia and multiple myeloma. Blood cancer journal, 12 (7). p. 110. ISSN 2044-5385

Weiss, Andreas, Lorthiois, Edwige, Barys, Louise, Beyer, Kim, Bomio-Confaglia, Claudio, Burks, Heather, Chen, Xueying, Cui, Xiaoming, de Kanter, Ruben, Dharmarajan, Lekshmi, Fedele, Carmine, Gerspacher, Marc, Guthy, Daniel Alexander, Head, Victoria, Jaeger, Ashley, Jimenez Nunez, Eloisa, Kearns, Jeff, Leblanc, Catherine, Maira, Michel, Murphy, Jason, Oakman, Helen, Ostermann, Nils, Ottl, Johannes, Rigollier, Pascal, Roman, Danielle, Schnell, Christian, Sedrani, Richard, Shimizu, Toshio, Stringer, Rowan, Vaupel, Andrea, Voshol, Johannes, Wessels, Peter, Widmer, Toni, Wilcken, Rainer, Xu, Kun, Zecri, Frederic, Farago, Anna, Cotesta, Simona and Brachmann, Saskia (2022) Discovery, preclinical characterization, and early clinical activity of JDQ443, a structurally novel, highly potent, selective covalent oral inhibitor of KRASG12C. Discovery, preclinical characterization, and early clinical activity of JDQ443, a structurally novel, highly potent, selective covalent oral inhibitor of KRASG12C.

Wilbaux, Melanie, Demanse, David, Gu, Gary, Jullion, Astrid, Myers, Andrea, Katsanou, Vasiliki and Meille, Christophe (2022) Contribution of machine learning to tumor growth inhibition modeling for hepatocellular carcinoma patients under Roblitinib (FGF401) drug treatment. CPT: pharmacometrics & systems pharmacology. ISSN 2163-8306

Wolf, Babette, Piksa, Mateusz, Voedisch, Bernd, Patoux, Agnes, Besson, Thierry, Schindler, Patrick, Cordier, Valerie, Perrot, Ludovic, Brees, Dominique and Kammueller, Michael (2022) Therapeutic antibody glycosylation impacts antigen recognition and immunogenicity. Immunology. ISSN 1365-2567

Yang, Tong-yuan, Braun, Manuela, Wibke, Lembke, McBlane, Fraser, Kamerud, John, DeWall, Stephen, Tarcsa, Edit, Fang, Xiaodong, Hofer, Lena, Kavita, Uma, Upreti, Vijay V., Gupta, Swati, Loo, LiNa, Johnson, Alison J., Jawa, Vibha, Chandode, Rakesh Kantilal, Vinzing, Maya and Xia, Cindy Q. (2022) Immunogenicity Assessment of AAV-based Gene Therapies: An IQ Consortium Industry White Paper. Molecular therapy - methods and clinical development, 26. pp. 471-494. ISSN 2329-0501

Zaghlool, Shaza B., Gudmundsdottir, Valborg, Jennings, Lori, Gudnason, Vilmundar and Suhre, Karsten (2022) Metabolic and proteomic signatures of type 2 diabetes subtypes in an Arab population. Nature communications, 13 (1). p. 7121. ISSN 2041-1723

Zevnik, Branko, Jerchow, Boris and Buch, Thorsten (2022) 3R measures in facilities for the production of genetically modified rodents. Lab animal, 51 (6). pp. 162-177. ISSN 1548-4475

Zevnik, Branko, Jerchow, Boris and Buch, Thorsten (2022) 3R Measures in facilities for the production of genetically modified rodents. Lab animal, 51 (6). pp. 162-177. ISSN 1548-4475; 0093-7355

Zhang, Luqing, Cunningham, Jonathan, Claggett, Brian, Jacob, Jaison, Mendelson, Mike, Serrano Fernandez, Pablo, Kaiser, Sergio, Yates, Denise, Healey, Margaret, Chen, Chien-Wei, Turner, Gordon, Patel-Murray, Natasha, Zhao, Faye, Beste, Michael, Laramie, Jason, Abraham, William, Jhund, Pardeep, Kober, Lars, Packer, Milton, Rouleau, Jean, Zile, Michael, Prescott, Margaret, Lefkowitz, Martin, McMurray, John, Solomon, Scott and Chutkow, William (2022) Aptamer Proteomics for Biomarker Discovery in Heart Failure With Reduced Ejection Fraction. Circulation, 146 (18). pp. 1411-1414. ISSN 1524-4539

Zhang, Luqing, Cunningham, Jonathan, Claggett, Brian, Jacob, Jaison, Mendelson, Mike, Serrano Fernandez, Pablo, Kaiser, Sergio, Yates, Denise, Healey, Margaret, Chen, Chien-Wei, Turner, Gordon, Patel-Murray, Natasha, Zhao, Faye, Beste, Michael, Laramie, Jason, Abraham, William, Jhund, Pardeep, Kober, Lars, Packer, Milton, Rouleau, Jean, Zile, Michael, Prescott, Margaret, Lefkowitz, Martin, McMurray, John, Solomon, Scott and Chutkow, William (2022) Aptamer Proteomics for Biomarker Discovery in Heart Failure with Reduced Ejection Fraction. Circulation. ISSN 1524-4539

Zhou, Yu and Wang, Yueju (2022) Sample Preparation Matters for Peptide Mapping to Evaluate Deamidation of Adeno-Associated Virus Capsid Proteins Using Liquid Chromatography–Tandem Mass Spectrometry. Human Gene Therapy, 33 (15 and). pp. 821-828.

Zula, Ales, Zidar, Mitja, Lebar, Blaz, Proj, Matic, Strasek, Nika, Gobec, Stanislav and Milicic, Goran (2022) Discovery of compounds with viscosity-reducing effects on biopharmaceutical formulations with monoclonal antibodies. Computational and structural biotechnology journal, 20. pp. 5420-5429. ISSN 20010370

de Esch, Iwan J P, Erlanson, Daniel A, Jahnke, Wolfgang, Johnson, Christopher N and Walsh, Louise (2022) Fragment-to-Lead Medicinal Chemistry Publications in 2020. Journal of medicinal chemistry, 65 (1). pp. 84-99. ISSN 1520-4804

Žuntar, Timotej, Ličen, Matjaž, Kuzman, Drago and Osterman, Natan (2022) Real-time imaging of monoclonal antibody film reconstitution after mechanical stress at the air-liquid interface by Brewster angle microscopy. Colloids and surfaces. B, Biointerfaces, 218. p. 112757. ISSN 1873-4367

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