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Items where Year is 2022

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Number of items: 132.

Adachi, Yuichiro, Fu, Fumin, Pietropaolo, Michael, Pandit, Shilpa, Li, Weiyan, Murakami, Yutaka, Grewal, Pam, Lussier, Jen, Deyneko, Galina, Turner, Gordon, Shetty, Suraj, Tarnavski, Oleg, Liu, Jing, Cui, Lei, Taggart, Andrew, Waters, Gerry and Coughlin, Shaun (2022) Lack of authentic atrial fibrillation in commonly used murine atrial fibrillation models. PloS one, 17 (1). e0256512. ISSN 1932-6203

Ahmed Madny, Muzaffaruddin, Deshpande, Pandurang, Tumuluri, Sri Venkata, Borde, Parag Prakash and Sangana, Ramachandra (2022) Utilization of in silico tools to investigate the in vivo performance of vildagliptin modified release (MR) 100 mg tablets in healthy subjects using physiologically based biopharmaceutics modeling (PBBM) and evaluate an approach to establish clinically relevant dissolution specifications. AAPS PharmSciTech, 23 (108). pp. 1-17. ISSN 1530-9932

Allmendinger, Thomas, Furet, Pascal, Denay, Regis, Kotoni, Dorina, Bixel, Dominique and Anokwah, Daniel K. (2022) 9-epi-Artemisinin - How a single stereo center affects chemical reactivity and activity. Helvetica Chimica Acta. ISSN 0018-019X1522-2675

Axelsson, Gisli Thor, Gudmundsson, Gunnar, Aspelund, Thor, Putman, Rachel, Gudmundsson, Elias F, Hatabu, Hiroto, Gudmundsdottir, Valborg, Gudjonsson, Alexander, Launer, Lenore J, Jennings, Lori, Hunninghake, Gary M, Emilsson, Valur and Gudnason, Vilmundur (2022) The Proteomic Profile of Interstitial Lung Abnormalities. American journal of respiratory and critical care medicine. ISSN 1535-4970

Badaoui, Magd , Buigues, Pedro J., Berta, Dénes , Mandana, Gaurav M., Kato, Mitsunori, Dickson, Callum, Hornak, Viktor, Molteni, Carla , Parsons, Simon D. and Rosta, Edina (2022) Combined Free-Energy Calculation and Machine Learning Methods for Understanding Ligand Unbinding Kinetics. Journal of chemical theory and computation. ISSN 1549-9626

Badee, Justine Marine (2022) Current Practices, Gap Analysis and Proposed Roadmaps for PBPK Modeling of Cytochrome P450 Induction: An Industry Perspective. CPT: pharmacometrics & systems pharmacology..

Barabas, Amanda J., Aryal, Uma K. and Gaskill, Brianna N. (2022) Protein profiles from used nesting material, saliva, and urine correspond with social behavior in group housed male mice, Mus musculus. Journal of Proteomics, 266. p. 104685. ISSN 18743919

Barabas, Amanda J., Robbins, Lindsey A. and Gaskill, Brianna N. (2022) Home cage measures of Alzheimer's disease in the rTg4510 mouse model. Genes, Brain and Behavior, 21 (2). ISSN 1601-1848

Bassand, Celine, Verin, Jeremy, Lamatsch, Martin, Siepmann, Florence and Siepmann, Juergen (2022) How agarose gels surrounding PLGA implants limit swelling and slow down drug release. Journal of controlled release : official journal of the Controlled Release Society, 343. pp. 255-266. ISSN 1873-4995

Bechtold-Peters, Karoline (2022) Industry Perspective on the use and Characterization of Polysorbates for Biopharmaceutical Products Part 1: Survey Report on Current State and Common Practices for Handling and Control of Polysorbates. Journal of pharmaceutical sciences, 111 (5). pp. 1280-1291. ISSN 00223549

Bechtold-Peters, Karoline, Paboojian, Stephen and Weikart, Christopher (2022) Improved Drug Stability Stored in Lubricant-Free Hybrid Syringes. American pharmaceutical review, 25 (4 (May). ISSN 10998012

Beckmann, Nicolau (2022) Editorial for "Evaluation of Dynamic Contrast-Enhanced MRI Measures of Lung Congestion and Endothelial Permeability in Heart Failure: A Prospective Method Validation Study”. Journal of Magnetic Resonance Imaging. ISSN 1053-18071522-2586

Berghausen, Joerg, Petersson, Carl, Zhou, Xin, Cebrian, Brian, Davies, Michael, DeMent, Kevin, Eddershaw, Peter, Emami Riedmaier, Arian, Leblanc, Alix, Manveski, Nenad, Marathe, Punit, Mavroudis, Panteleimon, McDougall, Robin, Parrott, Neil, Reichel, Andreas, Rotter, Charles, Tess, David, Volak, Laurie, Xiao, Guangqing, Yang, Zhen and Baker, James (2022) Current approaches for predicting human PK for small molecule development candidates: Findings from the IQ Human PK Prediction Working Group Survey. The AAPS journal.

Betschart, Claudia, Faller, Michael, Zink, Florence, Hemmig, Rene, Blank, Jutta, Vangrevelinghe, Eric, Bourrel, Marjorie, Glatthar, Ralf, Behnke, Dirk, Barker, Kerstin, Heizmann, Andreas, Angst, Daniela, Nimsgern, Pierre, Jacquier, Sebastien, Junt, Tobias, Collignon Zipfel, Geraldine, Ruzzante, Giulia, Loetscher, Pius, Limonta, Sarah, Hawtin, Stuart, Andre, Cedric Bernard, Boulay, Thomas, Feifel, Roland and Knoepfel, Thomas (2022) Structure-based optimization of a fragment like TLR8 binding screening hit to an in vivo efficacious TLR7/8 antagonist. ACS Medicinal Chemistry Letters. ISSN 1948-58751948-5875

Bluemel, Oliver, Bechtold-Peters, Karoline, Anuschek, Moritz, Buecheler, Jakob, Hoelzl, Georg and Friess, Wolfgang (2022) The effect of mAb and excipient cryoconcentration on long-term frozen storage stability - Part 1: Higher molecular weight species and subvisible particle formation. International journal of pharmaceutics: X, 4. p. 100108. ISSN 2590-1567

Bluemel, Oliver, Buecheler, Jakob, Hauptmann, Astrid, Hoelzl, Georg, Bechtold-Peters, Karoline and Friess, Wolfgang (2022) The effect of mAb and excipient cryoconcentration on long-term frozen storage stability - part 2: Aggregate formation and oxidation. International journal of pharmaceutics: X, 4. p. 100109. ISSN 2590-1567

Bluemel, Oliver, Friess, Wolfgang, Rodrigues, Miguel, Geraldes, Vitor, Bechtold-Peters, Karoline, Buecheler, Jakob, Hauptmann, Astrid and Hoelzl, Georg (2022) Evaluation of Two Novel Scale-Down Devices for Testing Monoclonal Antibody Aggregation During Large-Scale Freezing. Journal of pharmaceutical sciences. ISSN 1520-6017

Blume, T, Filser, SS, Sgobo, C, Peters, F, Neumann, Ulf, Shimshek, Derya, Saito, T, Saido, T, Brendel, M and Herms, J (2022) β‐secretase inhibition prevents structural spine plasticity deficits in App NL-G-F mice. Frontiers in aging neuroscience., 14. ISSN 1663-4365

Boulton, Craig (2022) People of TM: Video of Craig Boulton. LinkedIn & Youtube.

Bowman, Christopher, Barrow, Paul, Erkman, Linda and Muller, Mireille (2022) Science-based approach to harmonize contraception recommendations in clinical trials and pharmaceutical labels. Clinical pharmacology and therapeutics. ISSN 1532-6535

Bray, Mark, Durand, Eric, de Weck, Antoine, Fang, Jian, Gabriel, Daniela, Janssens, Rens, Moutsatsos, Ioannis, Spiegel, Stephan and Zhang, Xian (2022) High-content cellular screen image analysis benchmark study. bioRxiv.

Bruin, Gerardus and Walles, Markus (2022) Absorption, Distribution, Metabolism, and Excretion (ADME) of Therapeutic Proteins: A White Paper on Current Industry Practices and Future Perspectives. Drug metabolism and disposition. ISSN doi: 10.1124/dmd.121.000461

Bunc, Marko, Boncina, Matjaz, Graf, Christian, Hadži , San and Lah, Jurij (2022) Aggregation Time Machine: A Platform for the Prediction and Optimization of Long-Term Antibody Stability Using Short-Term Kinetic Analysis. Journal of Medicinal Chemistry, 65 (3). pp. 2623-2632. ISSN 0022-26231520-4804

Böttinger, Katharina, Paul, Katrin, Esser-Skala, Wolfgang, Segl, Marius, Herwig, Christoph and Huber, Christian (2022) At-line quantitative profiling of monoclonal antibody products during bioprocessing using HPLC-MS. Analytica chimica acta, 1207. p. 339813. ISSN 1873-4324

Casado-García, Ana, Isidro-Hernández, Marta , Oak, Ninad, Mayado, Andrea , Mann-Ran, Christine, Raboso-Gallego, Javier , Alemán-Artega, Silvia , Buhles, Alexandra, Sterker, Dario, Blanco, Oscar, Orfao, Alberto, Alonso-López, Diego, De Las Rivas, Javier, Riesco, Susana, Prieto-Matos, Pablo, Criado, Francisco Javier García, Cenador, María Begoña García, Radimerski, Thomas, Ramírez-Orellana, Manuel, Cobaleda, César, Yang, Jun J, Vicente-Dueñas, Carolina, Weiss, Andreas, Nichols, Kim E and Sánchez-García, Isidro (2022) Transient JAK/STAT pathway inhibition prevents natural occurring B-ALL development in genetically predisposed Pax5+/- mice. Cancer research, Epub a (canres). ISSN 1538-7445; 0008-5472

Charmont, Stephane, Sangana, Ramachandra and Valentin, Marie-Anne (2022) Development, validation and application of a liquid chromatography-tandem mass spectrometry method for the activity and inhibition of DPP-4. Bioanalysis, 14 (6). pp. 369-378. ISSN 1757-6199

Chen, Jin, Gu, Jessie, Shah, Bharti, Stringer, Rowan, Reis da Silva Torrao, Leonel, Hackling, Melissa, Nidamarthy, Prasanna, Prince, William and Woessner, Ralph (2022) Pharmacokinetics of Tropifexor, a Potent Farnesoid X Receptor Agonist, in Participants With Varying Degrees of Hepatic Impairment. Journal of clinical pharmacology, 62 (4). pp. 520-531. ISSN 1552-4604

Clark, Kirk, Kulathila, Raviraj, Wright, Kirk, Isome, Yuko, Sage, David, Yang, Yi and Christodoulou, Constantina (2022) Crystal structure of 2-PG bound to BPGM. RCSB Protein Data Bank.

Davis, Haley J., Barabas, Amanda J. and Gaskill, Brianna N. (2022) Titrating the preferences of altered lighting against temperature in female CD-1 laboratory mice, Mus musculus. Applied Animal Behaviour Science, 246. p. 105541. ISSN 01681591

Davis, John, Kulmatycki, Ken, Humphries, Sara C, Iqbal, Sajida, Kamel, Amin, Lao, Yanbin, Liu, Xiumin, Rogers , John, Snoeys, Jan, Weng, Yan, Vigil, Adam, Wiethoft, Christopher M and Wittwer, Matthias B (2022) Considerations and recommendations for assessment of plasma protein binding and drug-drug interactions for siRNA therapeutics. Nucleic acids research, 50 (11). pp. 6020-6037.

Dawson King, Janet, Accart Gris, Nathalie, Obrecht, Michael, Lambert, Christian, Flueckiger, Manuela, Kreider, Julie, Hatakeyama, Shinji, Richards, Peter and Beckmann, Nicolau (2022) Degenerative joint disease induced by repeated intra-articular injections of monosodium urate crystals in rats as investigated by translational imaging. Scientific reports, 12 (1). p. 157. ISSN 2045-2322

De Luca, Valeria (2022) Measuring Health-Related Quality of Life With Multimodal Data: Viewpoint. Journal of medical internet research, 24 (5). ISSN 1438-8871

Dhandapani, Rahul, Neri, Marilisa, Bernhard, Mario, Brzak, Irena, Schweizer, Tatjana, Rudin, Stefan, Stefanie, Joller, Berth, Ramon, Kernen, Jasmin, Neuhaus, Anna, Waldt, Annick, Cuttat-Theurillat, Rachel, Naumann, Ulrike, Gubser Keller, Caroline, Roma, Guglielmo, Feuerbach, Dominik, Shimshek, Derya, Ulf, Neumann, Gasparini, Fabrizio and Galimberti, Ivan (2022) Sustained Trem2 stabilization accelerates microglia heterogeneity and Aβ pathology in a mouse model of Alzheimer’s disease. Cell reports, 39 (9). ISSN 2211-1247

DiDominick, Sarah, Abozeid, Ahmed M, Chen, Xueying, Stammberger, Uz, Santoro, Armando, Su, Wu-Chou, Navarro, Alejandro, Simonelli, Matteo, Yang, James CH, Ardizzoni, Andrea, Barlesi, Fabrice, Kang, Jin Hyoung and Felip, Enriqueta (2022) Phase Ib/II study of ceritinib in combination with ribociclib in patients with ALK-rearranged non-small cell lung cancer. Lung cancer (Amsterdam, Netherlands), 166. pp. 170-177. ISSN 1872-8332

Dickson, Callum, Walker, Ross and Gould, Ian (2022) Lipid21: Complex Lipid Membrane Simulations with AMBER. Journal of chemical theory and computation. ISSN 1549-9626

Duca, Matteo, Lim, Darren Wan-Teck , Subbiah, Vivek, Takahashi, Shunji, Sarantopoulos, John, Varga, Andrea, D'Alessio, Tony, Abrams, Tinya, Sheng, Qing, Tan, Eugene, Cintrao Dos Santos Rosa, Maria, Gonzalez Maffe, Juan, Sand Dejmek, Janna, Fabre, Claire and Martin, Miguel (2022) A First-in-Human, Phase 1, Multicenter, Open-label, Dose-Escalation Study of PCA062, an Antibody-Drug Conjugate Targeting P-Cadherin, in Adult Patients with Solid Tumors. Molecular cancer therapeutics, 21 (4). pp. 625-634. ISSN 1535-7163

Ebersbach, Hilmar, Jascur, Julia, Keshvari, Sahar, Genz, Berit, Teakle, Ngari, Caruso, Melanie, Cestari, Michele F, Patkar, Omkar L, Tse, Brian WC, Sokolowski, Kamil A, MacDonald, Kelly P.A., Miller, Gregory, Ramm, Grant A, Pettit, Allison R, Clouston, Andrew D, Powell, Elizabeth E, Hume, David A and Irvine, Katharine M (2022) Therapeutic potential of macrophage colony-stimulating factor (CSF1) in chronic liver disease. Disease models & mechanisms. ISSN 1754-8411

Eichler, Gabriel, Imbert, Georges, Branson, Janice, Balibey, Rene, Laramie, Jason, Hersch, Greg, Askin, Scott, Kauffmann, Audrey, Speyer, Peter, Cochrane, Andrew, Mannan, Haripriya, Rudolph, Amy, Asakiewicz, Christopher, McGovern, Patricia, Ramanathan, Krishnan and Ballard, Mary (2022) Democratizing data at Novartis through clinical trial data access. Drug discovery today. ISSN 1878-5832

Ertl, Peter (2022) Substituents of life: The most common substituent patterns present in natural products. Bioorganic & medicinal chemistry, 54. p. 116562. ISSN 1464-3391

Ertl, Peter, Altmann, Eva, Racine, Sophie and Lewis, Richard (2022) Ring replacement recommender: Ring modifications for improving biological activity. European journal of medicinal chemistry, 238. p. 114483. ISSN 1768-3254

Fichter, Marie, Richter, Gesa, Bepperling, Alexander and Wassmann, Paul (2022) Pre-clinical in-vitro studies on parameters governing immune complex formation. Pharmaceutics.

Flandre, Thierry, Mansfield, Keith, Espie, Pascal, Rubic-Schneider, Tina and Ulrich, Peter (2022) Immunosuppression Profile of CFZ533 (Iscalimab), a Non-Depleting Anti-CD40 Antibody, and the Presence of Opportunistic Infections in a Rhesus Monkey Toxicology Study. Toxicologic pathology. pp. 1-13.

Forest, Thomas, Aeffner, Famke, Bangari, Dinesh, Bawa, Bhupinder, Carter, Jonathan, Fikes, James, High, Wanda, Hayashi, Shim-mo, Jacobsen, Matthew, McKinney, LuAnn, Rudmann, Daniel, Steinbach, Thomas, Schumacher, Vanessa, Turner, Oliver, Ward, Jerrold and Willson, Cynthia (2022) Scientific and Regulatory Policy Committee Points to Consider*: Primary Digital Histopathology Evaluation and Peer Review for Good Laboratory Practice (GLP) Nonclinical Toxicology Studies. Toxicologic pathology.

Francotte, Eric and Huynh, Dan (2022) Immobilization of 3,5-Dimethylphenyl Carbamate of Cellulose and Amylose on Silica by Photochemical and Thermal Radical Processes. Immobilization of 3,5-dimethylphenyl carbamate of cellulose and amylose on silica by photochemical and thermal radical processes, 2022. pp. 1-21. ISSN 1520-636X

Freedman, Benjamin R, Kuttler, Andreas, Beckmann, Nicolau, Nam, Sungmin, Kent, Daniel, Farshad, Ramazani, Schuleit, Michael, Accart Gris, Nathalie, Rock, Anna, Li, Jianyu, Kurz, Markus, Fisch, Andreas, Ullrich, Thomas, Hast, Michael W, Tinguely, Yann , Weber, Eckhard and Mooney, David J (2022) Enhanced tendon healing by a tough hydrogel with an adhesive side and high drug-loading capacity. Nature Biomedical Engineering.

Gallou, Fabrice (2022) Allylations of Aryl/Heteroaryl Ketones: Neat, Clean, and Green. Applications to Targets in the Pharma- and Nutraceutical Industries. Green chemistry, 24. pp. 4909-4914.

Gallou, Fabrice (2022) The Catalytic Formation of Atropisomers and New Stereocenters via Asymmetric Suzuki-Miyaura Couplings. ACS catalysis, 12 (9). pp. 4918-4937.

Gallou, Fabrice (2022) Phosphine Ligand-Free Bimetallic Ni(0)Pd(0) Nanoparticles as a Catalyst for Facile, General, Sustainable, and Highly Selective 1,4-Reductions in Aqueous Micelles. ACS Appl. Mater. Interfaces, 14 (5). pp. 6754-6761.

Gallou, Fabrice (2022) Selectivity Arising from Synergy Between Two Metals and Aqueous Micelle: Nickel-Palladium Bimetallic Nanoparticles for Facile and Highly Selective 1,4-Reduction of Chalcones. ACS Appl. Mater. Interfaces, 14 (5). pp. 6754-6761.

Gallou, Fabrice (2022) Sustainable and Bench-Stable Photoactive Aqueous Nanoaggregates of Cu(II) for ppm Cu(I) Catalysis in Water. Advanced materials.

Gallou, Fabrice (2022) Water: An Underestimated Solvent for Amide Bond-Forming Reactions. ACS Sustainable Chemistry & Engineering, 10 (16). pp. 5299-5306.

Gallou, Fabrice, Grandeury, Arnaud and Jones, Graham (2022) Cultural Diversity Drives Innovation: Does Institutional Residence Time Impact Behaviors? Journal of Innovation Management, 9 (9). pp. 1-9. ISSN 2183-0606

Garcia, Francisco, Hoopes, Caleb, Sarkar, Akash, Kuehl, Nicholas, Barkan, Dave, Collins, Nicole, Bramhall, Taylor, Meister, Glenna, Hsu, Chien-Hsiang, Jones, Michael, Schirle, Markus and Taylor, Michael (2022) Donor-Acceptor Pyridinium Salts for Photo-Induced Electron-Transfer-Driven Modification of Tryptophan in Peptides, Proteins, and Proteomes Using Visible Light. Journal of the American Chemical Society. ISSN 1520-5126

Garcia, Francisco, Hoopes, Caleb, Sarkar, Akash, Kuehl, Nicholas, Barkan, Dave, Collins, Nicole, Meister, Glenna, Bramhall, Taylor, Hsu, Chien-Hsiang, Jones, Michael, Schirle, Markus and Taylor, Michael (2022) Donor-Acceptor Pyridinium Salts for Photo-Induced Electron-Transfer-Driven Modification of Tryptophan in Peptides, Proteins, and Proteomes Using Visible Light. Journal of the American Chemical Society, 144 (14). pp. 6227-6236. ISSN 1520-5126

Glinsek, Katja, Kramer, Lovro, Krajnc, Aleksander, Kranjc, Eva, Pirher, Nina, Marusic, Jaka, Hellmann, Leon, Podobnik, Barbara, Strukelj, Borut, Auslaender, David Sebastian and Gaber, Rok (2022) Coupling CRISPR interference with FACS enrichment: New approach in glycoengineering of CHO cell lines for therapeutic glycoprotein production. Biotechnology journal. e2100499. ISSN 1860-7314

Godinez Navarro, William, Ma, Eric, Chao, Alexander, Pei, Amy, Skewes-Cox, Peter, Canham, Steve, Jenkins, Jeremy, Young, Joe, Martin, Eric and Guiguemde, Armand (2022) Design of potent antimalarials with generative chemistry. Nature Machine Intelligence, 4. pp. 180-186. ISSN 2522-5839

Gudjonsson, Alexander, Gudmundsdottir, Valborg, Gudmundsson, Elias F, Jonsson, Brynjolfur G, Launer, Lenore J, Lamb, John R, Jennings, Lori, Aspelund, Thor, Emilsson, Valur and Gudnason, Vilmundur (2022) A genome-wide association study of serum proteins reveals shared loci with common diseases. Nature communications.

Guerini, Danilo (2022) STING agonists/antagonists: their potential as therapeutics and future developments. Cells., 11. p. 1159.

Guillon, Antoine, Diakite, Deborah, Cezard, Adeline, Baranek, Thomas, Bourgeais, Jérôme, Picou, Frédéric, Hervé, Virginie, Carballido, Jose, Desbarats, Lydie Nadal, Auvet, Adrien, Dingli, Florent, Turtoi, Andrei, Le Gouellec, Audrey, Fauvelle, Florence, Crépin, Thibaut, Hiemstra, Pieter S, Paget, Christophe, Loew, Damarys, Herault, Olivier, Naffakh, Nadia, Le Goffic, Ronan and Si-Tahar, Mustapha (2022) Host succinate inhibits influenza virus infection through succinylation and nuclear retention of the viral nucleoprotein. The EMBO journal, 41 (12). e108306. ISSN 1460-2075

Gurtan, Allan, Dominy, John, Khalid, Shareef, Vong, Linh, Caplan, Shari, Currie, Treeve, Richards, Sean, Lamarche, Lindsey, Denning, Daniel, Rasheed, Asif, Hameed, Shahid, ul-Asar, Zameer, Saleem, Imran, Jalal, Anjun, Abbas, Shahid, Rasheed, Syed, Memon, Fazal-ur-Rehman, Ishaq, Mohammad, Frossard, Philippe and Saleheen, Danish (2022) Analyzing human knockouts to validate GPR151 as a therapeutic target for reduction of body mass index. PLoS genetics, 18 (4). e1010093. ISSN 1553-7404

Hahaut, Vincent, Pavlinic, Dinko, Cowan, Cameron, Schuierer, Sven, Carbone, Walter, Roma, Guglielmo and Picelli, Simone (2022) Lightning Fast and Highly Sensitive Full-Length Single-cell sequencing using FLASH-Seq. Nature biotechnology, 40. ISSN 1087-0156

Hamzic, Seid, Lewis, Richard, Desrayaud, Sandrine, Soylu, Cihan, Fortunato, Mike, Gerebtzoff, Gregori and Rodriguez Perez, Raquel (2022) Predicting in vivo brain penetration using multitask graph neural networks. Journal of chemical information and modeling.

Hamzic, Seid, Lewis, Richard, Desrayaud, Sandrine, Soylu, Cihan, Fortunato, Mike, Gerebtzoff, Gregori and Rodriguez Perez, Raquel (2022) Predicting in vivo brain penetration using multitask graph neural networks. Journal of Chemical Information and Modeling. ISSN 1549-95961549-960X

Hamzic, Seid, Lewis, Richard, Desrayaud, Sandrine, Soylu, Cihan, Fortunato, Mike, Gerebtzoff, Gregori and Rodriguez Perez, Raquel (2022) Predicting in vivo brain penetration using multitask graph neural networks. Journal of Chemical Information and Modeling. ISSN 1549-95961549-960X

Henning, Nathaniel, Boike, Lydia, Spradlin, Jessica, Ward, Carl, Zhang, Erika, Belcher, Bridget, Brittain, Scott, Hesse, Matthew, Dovala, Dustin, McGregor, Lynn, Valdez Misiolek, Rachel, Wingert Plasschaert, Lindsey, Rowlands, David, Wang, Feng, fuller, daniel, Estes, Abigail, Frank, Andreas, Randal, Katelyn, Panidapu, Anoohya, McKenna, Jeffrey, Tallarico, John, Schirle, Markus, Nomura, Daniel and Liu, Gang (2022) Deubiquitinase-targeting chimeras for targeted protein stabilization. Nature chemical biology. ISSN 1552-4469

Hoch, Matthias, Huth, Felix, SATO, MASAHIKO, Sengupta, Tirtha, Quinlan, Michelle, Dodd, Stephanie, Kapoor, Shruti and Hourcade-Potelleret, Florence (2022) Pharmacokinetics of asciminib in the presence of CYP3A or P-gp inhibitors, CYP3A inducers, and acid-reducing agents. Clinical and Translational Science. ISSN 1752-80541752-8062

Hoch, Matthias, Sengupta, Tirtha and Hourcade-Potelleret, Florence (2022) Pharmacokinetic Drug Interactions of Asciminib With the Sensitive Cytochrome P450 Probe Substrates Midazolam, Warfarin and Repaglinide in Healthy Volunteers. Clinical and translational science. ISSN 1752-8062; 1752-8054

Horvath, Courtney (2022) People of TM: Video of Courtney Horvath. LinkedIn.

Huang, Ying, Zhang, Jeff, Sendzik, Martin, Gao, Zhenting, Sun, Yongfeng, Wang, Long, Zhang, Lijun, Blanz, Joachim, Dubost, Valerie, Chen, Zijun, Fang, Douglas, Gu, Justin, Kiffe, Michael, Li, Ling, Luo, Fangjun, Luo, Xiao, Mistry, Prakash, Pearson, David, Piaia, Alessandro, Qi, Wei, Scheufler, Clemens, Terranova, Remi, Weiss, Andreas, Yu, Zhengtian, Zeng, Jue, Zhang, Hailong, Zhang, Jiangwei, Zhang, Qiong, Zhao, Kehao, Zhao, Mengxi, Atadja, Peter, Dillon, Michael, Jeay, Sebastien Jeay, Li, En, Moggs, Jonathan, Pissot Soldermann, Carole, Oyang, Counde and Lingel, Andreas (2022) Discovery of the Clinical Candidate MAK683: An EED-Directed, Allosteric, and Selective PRC2 Inhibitor for the Treatment of Advanced Malignancies. Journal of Medicinal Chemistry, 65 (7). pp. 5317-5333. ISSN 0022-26231520-4804

Jang, Jun Ho, Wong, Lily, Ko, Bor-Sheng, Yoon, Sung-Soo, Li, Katie, Baltcheva, Irina, Nidamarthy, Prasanna, Chawla, Raghav, Junge, Guido and Yap, Eng Soo (2022) Iptacopan monotherapy in patients with paroxysmal nocturnal hemoglobinuria: a 2-cohort open-label proof-of-concept study. Blood advances. ISSN 2473-9537

Jennings, Lori (2022) SomaScan Proteomics Profiling - An Overview for (potential) External Collaborators. general distribution.

Ji, Yan, Huang, Pai-Hsi, Woolfenden, Stephen and Myers, Andrea (2022) Model-based dose selection to inform translational clinical oncology development of WNT974, a first-in-class Porcupine inhibitor. Clinical and translational science. ISSN 1752-8062

Ji, Yan, Huang, Pai-Hsi, Woolfenden, Stephen and Myers, Andrea (2022) Model-based dose selection to inform translational clinical oncology development of WNT974, a first-in-class Porcupine inhibitor. Clinical and translational science. pp. 1-10. ISSN 1752-8062

Jones, Graham, Freeman, Jason, Mann, Allison and Khanna, Amit (2022) Physician Centricity in the Deployment of Digital Solutions for Neurological Conditions. DIGITAL HEALTH, 8 (1-2). pp. 1-2. ISSN 2055-20762055-2076

Kroemer, Markus and Ostermeier, Daniela (2022) Tackling Challenging Targets with High-Throughput Biophysical Screening at Novartis. Scaling Up Surface Plasmon Resonance-Based Screens to Increase Novel Hit Finding.

Lanshoeft, Christian, Lozac'h, Frederic and Higton, David (2022) Use of predicted versus measured CCS values from different instrument platforms, and isomer separation on the SELECT SERIES Cyclic IMS. Waters Application Note.

Lara, Zentsche, Jessica, Yazarians, Suman, Chakrabarty, Meagan, Hinze, April, Lukowski, Leo, Joyce and Alison, Narayan (2022) Biaryl bond formation through biocatalytic oxidative cross-coupling reactions. Nature, 603. pp. 79-85. ISSN https://doi.org/10.1038/s41586-021-04365-7

Lee, Judy (2022) Formulated oligonucleotide APIs: Regulatory aspects. Therapeutic innovation & regulatory science, 2022 (56). pp. 386-393. ISSN 2168-4790; 2168-4804

Lehermayr, Christian, Podobnik, Barbara and Graf, Christian (2022) Open channel for external industry technology providers to centrally upload technology offers to a Novartis web portal. https://digitalbrain.novartis.com/, n.a. (n.a.). n.a.-n.a.. ISSN n.a.

Lehmann, Hansjoerg, Knoepfel, Thomas and Ruppen, Thomas (2022) Scale-up of Diazonium Salts and Azides in a Three-step Continuous Flow Sequence. Organic Process Research & Development.

Lenz, Jan, Fuest, Frederik, Finek, Jan Hendrik, Bunjes, Heike, Kwade, Arno and Juhnke, Michael (2022) Tablet disintegration and dispersion under in vivo-like hydrodynamic conditions. Pharmaceutics, 14 (n.a.). pp. 1-25. ISSN 1999-4923

Li, Ying Fei, Combes, Francois Pierre, Hoch, Matthias, Lorenzo, Sebastien, Sy, Sherwin and Ho, Yu-Yun (2022) Population pharmacokinetics of asciminib in tyrosine kinase inhibitor-treated patients with Philadelphia chromosome-positive chronic myeloid leukemia in chronic and acute phases. Clinical Pharmacokinetics, 61 (5). ISSN 0312-5963

Linker, Stephanie, Schellhaas, Christian , Ries, Benjamin , Roth, Hans-Joerg, Fouche, Marianne, Rodde, Stephane and Riniker, Sereina (2022) Polar/Apolar Interfaces Modulate the Conformational Behavior of Cyclic Peptides with Impact on Their Passive Membrane Permeability. RSC advances, 12 (10). pp. 5782-5796.

Lopez, John, Bucher, Christoph, Beck, Janina, Berthelmann, Arne, Spyridon, Markos and Eisser, Stefan (2022) THE MISSING LINK: ENABLING LOADING OF 2-CHLOROTRITYL CHLORIDE RESIN IN N-BUTYLPYRROLIDINONE AS A GREEN SOLVENT. Organic Process Research & Development, 26 (5). pp. 1450-1457. ISSN 1083-61601520-586X

Loryan, Irena, Reichel, Andreas, Feng, Bo, Bundgaard, Christopher, Shaffer, Christopher, Kalvass, Cory, Bednarczyk, Dallas, Morrison, Denise, Lesuisse, Dominique, Hopper, Edmund, Terstappen, Georg, Fischer, Holger, Di, Li, Colclough, Nicola, Summerfield, Scott, Buckley, Stephen, Maurer, Tristan and Friden, Markus (2022) Unbound Brain-to-Plasma Partition Coefficient, Kp,uu,brain-a Game Changing Parameter for CNS Drug Discovery and Development. Pharmaceutical research. ISSN 1573-904X

Lüönd, Fabiana, Pirkl, Martin, Hisano, Mizue, Prestigiacomo, Vincenzo, Kalathur, Ravi Kr, Beerenwinkel, Niko and Christofori, Gerhard (2022) Hierarchy of TGFβ/SMAD, Hippo/YAP/TAZ, and Wnt/β-catenin signaling in melanoma phenotype switching. Life science alliance, 5 (2). ISSN 2575-1077

Madl, Amy, Liu, Chunzi, Cirera-Salinas, Daniel, Myung, David and Fuller, Gerald (2022) A Mucin-Deficient Ocular Surface Mimetic Platform for Interrogating Drug Effects on Biolubrication, Anti-Adhesion Properties, and Barrier Functionality. ACS Applied Materials & Interfaces, 14 (16). pp. 18016-18030. ISSN 1944-82441944-8252

Madren, Seth, McElroy, Will, Schultz-Kuszak, Kristin, Boumajny, Boris, Shu, Yao, Sautter, Sabine, Zhao, Helen C, Schadock-Hewitt, Abby, Chumsae, Chris, Ball, Nancy, Xiaoying, Zhang, Rish, Kimberly , Shukui, Zhang , Wurm, Christine , Cai, Sumin , Bauer, Scott P , Stella, Cinzia , Zheng, Laura, Roper, Brian , Michels, David A , Wu, Gang , Kocjan, Bostjan, Birk, Matej, Erdmann, Simon Erik, He, Xiaoping, Whittaker, Brad, Song, Yvonne, Barrett, Hannah, Strozyk, Kevin, Jing, Ye, Huang, Long, Mhatre, Vishal, McLean, Paul, Yu, Tiantian, Yang, Huijuan and Mattila, Minna (2022) Global intercompany assessment of ICIEF platform comparability for the characterization of therapeutic proteins. Electrophoresis.

Mann, Greg, Stanger, Frederic, Peschke, Theo, Schroer, Kirsten, Nguyen Trung, Nhat Quang, Burrer, Nathalie, Grassinger, Franziska, Piccioni, Lorenzo, Erdogan, Oemer, Heimburger, Jeremy, Koehl, Herve, Ertle, Heike, Denay, Regis, Dreier, Philippe and Schlama, Thierry (2022) Biocatalytic assembly of chemically modified oligonucleotides. Tetrahedron letters. ISSN 00404039

McKenna, Jeffrey, Schirle, Markus, Tallarico, John, Brittain, Scott, Scholz, Spencer, Near, Katherine, Page, Annika, Spradlin, Jessica, Nomura, Daniel and Toste, F Dean (2022) Photo-Brook rearrangement of acyl silanes as a new tool for photoaffinity probes design. Chem Sci.

Meseck, Emily, Mansfield, Keith, Hudry, Eloise, McElroy, Cameron and Guibinga, Ghiabe (2022) Intrathecal sc-AAV9-CB-GFP: Systemic Distribution Predominates Following Single-Dose Administration in Cynomolgus Macaques. Toxicologic pathology.

Meyer, Robina Mareike, Aleshkevich, Sofya, Berger, Lukas, Nerkamp, Joerg, Scheler, Stefan and Friess, Wolfgang (2022) Characterization of the aggregation propensity of charge variants of recombinant human growth hormone. International journal of pharmaceutics, 621. p. 121760. ISSN 1873-3476

Milton, Mark, Dodge, Robert and Potthoff, Bernd (2022) 2021 White Paper on Recent Issues in Bioanalysis: TAb/NAb, Viral Vector CDx, Shedding Assays; CRISPR/Cas9 & CAR-T Immunogenicity; PCR & Vaccine Assay Performance; ADA Assay Comparability & Cut Point Appropriateness. Bioanalysis.

Moebitz, Henrik, Gruenenfelder, Bjoern, Kiffe, Michael, Ramos, Rita, Ramulu, Poddutoori, Kiran, Aithal, Mark, Bock, Sanjeev, BS, Shekar, Chelur, T S, Devaraja, Sreevalsam, Gopinath, Andrea, Gerken, Charamanna , KB, Maithreyi, Krishnaswami, John, Langowski, Sudarshan, Madapa, Kishore, Narayanan, Ravi Kumar , P, Chetan, Pandit, Sunil Kumar, Panigrahi, Mark, Perrone, Murali, Ramachandra, Anuradha, Ramanathan, Susanta, Samajdar, Hosahalli, Subramanya and Eleni, Venetsanakos (2022) Discovery of MAP855, an efficacious and selective MEK1/2 inhibitor with ATP-competitive mode of action. Journal of Medicinal Chemistry.

Moraitis, Alexandra (2022) The function of 14-3-3 protein family and its connection with cancer review. University business..

Parmentier, Michael, Li, Wei and Steven, Alan (2022) Green Chemistry Articles of Interest to the Pharmaceutical Industry. Organic Process Research & Development. ISSN 1083-61601520-586X

Pearson, David, Jin, Yi, Romeo, Andrea, Birlinger, Bertrand-Luc, Schiller, Hilmar, Ji, Yan, Gunduz, Mithat, Baldoni, Daniela and Walles, Markus (2022) Species-dependent hepatic and intestinal metabolism of selective oestrogen receptor degrader LSZ102 by sulphation and glucuronidation. Xenobiotica. pp. 1-12. ISSN 0049-82541366-5928

Pearson, David, Jin, Yi, Romeo, Andrea, Birlinger, Bertrand-Luc, Schiller, Hilmar, Ji, Yan, Gunduz, Mithat, Baldoni, Daniela and Walles, Markus (2022) Species-dependent hepatic and intestinal metabolism of selective oestrogen receptor degrader LSZ102 by sulphation and glucuronidation. Xenobiotica; the fate of foreign compounds in biological systems. pp. 1-12. ISSN 1366-5928

Pivk-Lukancic, Petra, Drčar, Tjaša, Bruccoleri, Robert, Crnugelj, Martin and Mrak, Peter (2022) Teleocidin-producing genotype of Streptomyces clavuligerus ATCC 27064. Applied microbiology and biotechnology. ISSN 1432-0614

Poor, Stephen, Weissgerber, Georges, Adams, Christopher, Watters, Christie, Ferriere, Michael, Chastain, Jim, Gedif, Kinfemichael, Harit, Bhatt, David , Browning, Thomas, Ciulla, Louis , Glazer, Brian, Joondeph, Veeral , Sheeth and Grosskreutz, Cyndy (2022) A Randomized, Double-Masked, Multicenter Trial of Topical Acrizanib (LHA510), a Tyrosine Kinase VEGF-Receptor Inhibitor, in Treatment-Experienced Subjects With Neovascular Age-Related Macular Degeneration. American journal of ophthalmology, 239. pp. 180-189. ISSN 1879-1891

Prabhath, Anupama , Vernekar , Varadraj N, Esdaille, Caldon J, Eisenberg , Ellen , Lebaschi , Amir, Badon , Mary , Seyedsalehi, Amir, Dzidotor , Godwin , Tang, Xiaoyan , Dyment , Nathaniel , Thomopoulos , Stavros , Kumbar , Sangamesh G, Deymier, Alix, Weber, Eckhard and Laurencin , Cato T (2022) Pegylated insulin-like growth factor-1 biotherapeutic delivery promotes rotator cuff regeneration in a rat model. Journal of biomedical materials research. Part A. ISSN 1552-4965

Pretre, Vincent, Papadopoulos, Dimitrios, Regard, Jean, Pelletier, Marc and Woo, Janghee (2022) Interleukin-1 (IL-1) and the inflammasome in cancer. Cytokine, 153. ISSN 1043-4666

Quintavalle, Cristina, Meyer-Schaller, Nathalie, Roessler, Stephanie, Calabrese, Diego, Marone, Romina, Riedl, Tobias, Picco-Rey, Silvia, Panagiotou, Orestis A, Uzun, Sarp, Piscuoglio, Salvatore, Boldanova, Tuyana, Bian, Chaoran B, Semela, David, Jochum, Wolfram, Cathomas, Gieri, Mertz, Kirsten D, Diebold, Joachim, Mazzucchelli, Luca, Koelzer, Viktor H, Weber, Achim, Decaens, Thomas, Terracciano, Luigi M, Heikenwalder, Mathias, Hoshida, Yujin, Andersen, Jesper B, Thorgeirsson, Snorri S and Matter, Matthias S (2022) miR-579-3p Controls Hepatocellular Carcinoma Formation by Regulating the Phosphoinositide 3-Kinase-Protein Kinase B Pathway in Chronically Inflamed Liver. Hepatology communications. ISSN 2471-254X

Rawat, Manoj, Natasha , Manners, Vishnu, Priya , Abhishesh Kumar , Mehata and Madaswamy S, Muthu (2022) Theranostic Nanomedicines for the Treatment of Cardiovascular and Related Diseases: Current Strategies and Future Perspectives. Pharmaceuticals, 15 (4). p. 441. ISSN 1424-8247

Reddy, K. Raja , Totrov, Maxim , Lomovskaya, Olga, Griffith, David C. , Tarazi, Ziad , Clifton, Matt and Hecker, Scott J. (2022) Broad-spectrum cyclic boronate β-lactamase inhibitors featuring an intramolecular prodrug for oral bioavailability. Bioorganic & medicinal chemistry, 62. p. 116722. ISSN 1464-3391

Rees, David C, Kilinc, Yurdanur, Unal , Selma, Dampier, Carlton, Pace, Betty S, Kaya, Banu, Trompeter, Sara, Odame , Isaac, Mahlangu, Johnny, Unal, Sule, Brent, Julie, Grosse, Regine, Fuh, Beng R, Inusa, Baba PD, Koren, Ariel, Levin, Carina, McNamara, Elizabeth, Meiser, Karin, Hom, Douglas and Oliver, Stephen (2022) Inhibiting IL-1beta-mediated inflammation in pediatric and young adult patients with sickle cell anemia: a randomized, placebo-controlled, double-blind trial with canakinumab (ACZ885). Blood.

Reilly, Dorothy, Alharbi, Ebtisam, Gadiya, Yojana , Henderson, David, Zaliani, Andrea , Delfin-Rossaro, Alejandra , Cambon-Thomsen, Anne , Witt, Gesa , Welter, Danielle , Juty, Nick, Jay, Caroline, Goble, Carol, Satagopam, Venkata , Ioannidis, Vassilios , Gu, Wei and Gribbon, Phil (2022) Selection of datasets for FAIRification in Drug Discovery and Development: Which, Why, and How? Drug discovery today. ISSN 1878-5832

Rodriguez Perez, Raquel, Miljkovic, Filip and Bajorath, Jürgen (2022) Machine Learning in Chemoinformatics and Medicinal Chemistry. Annual review of biomedical data science. ISSN 2574-3414

Salvi, Amrita, Young, Alexandria N., Huntsman, Andrew C., Pergrande, Melissa, Korkmaz, Melissa A., Mize, Brittney K., Zhang, Xiaoli, Ratia, Kiira, Shelton IV, Claude, Brittain, Scott, Schirle, Markus, Thomas, Jason, Aldritch, Leslie N., Cologna, Stephanie M., Fuchs, James R. and Burdette, Joanna E. (2022) PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancer. Cell death & disease, 13 (1). p. 45. ISSN 2041-4889

Schiller, Hilmar, Huth, Felix, Schuhler, Carole, Drollmann, Anton Franz, Kaul, Martin, Woessner, Ralph, Shah, Bharti, Weis, Wendy and End, Peter (2022) Novel Bruton’s tyrosine kinase inhibitor remibrutinib: Assessment of drug-drug interaction potential as a perpetrator of cytochrome P450 enzymes and drug transporters and the impact of covalent binding on possible drug interactions. European journal of pharmaceutical sciences, 172. ISSN 09280987

Schoeberl, Birgit and Kearns, Jeff (2022) Navigating Between Right, Wrong, and Relevant: The Use of Mathematical Modeling in Preclinical Decision Making. Frontiers in pharmacology, 13. p. 860881. ISSN 1663-9812

Schwab, Nathalie, Nienhold, Ronny, Henkel, Maurice, Baschong, Albert, Graber, Anne, Frank, Angela, Mensah, Nadine, Koike, Jacqueline, Hernach, Claudia, Sachs, Melanie, Willi, Niels, Zsikla, Veronika, Junt, Tobias and Mertz, Kirsten (2022) COVID-19 Autopsies Reveal Underreporting of SARS-CoV-2 Infection and Scarcity of Co-infections. Frontiers in medicine, 9. p. 868954. ISSN 2296-858X

Scorrano, Fabrizio (2022) A New Feeder Device to Provide Cleaner and Accessible Diet Gel to Laboratory Mice. Laboratory Animal Science Professional. pp. 50-52.

Segal, Florencia (2022) People of TM: Video of Florencia Segal. LinkedIn.

Seror, Raphaele, Baron, Gabriel, Camus, Marine, Cornec, Divi, Perrodeau, Elodie, Bowman, Simon, Bombardieri, Michele, Bootsma, Hendrika, Gottenberg, Jaccques-Eric, Fisher, Benjamin, Hueber, Wolfgang, van Roon, Joel, Devauchelle-Pensec, Valerie, Gergely, Peter, Mariette, Xavier and Porcher, Raphael (2022) Development and preliminary validation of the Sjögren’s Tool for Assessing Response (STAR): a consensual composite score for assessing treatment effect in primary Sjögren’s syndrome. Annals of the rheumatic diseases : ARD, Online (Online). Online-Online. ISSN Online ahead of print

Skolnik, Suzanne, Barrett, Jaclyn, Yang, Wenzhan, Belliveau, Lisa and Patros, Kellyn (2022) Discovery solubility measurement and assessment with drug development in mind. Drug discovery today. ISSN 13596446

Snyder, Jennifer (2022) We Support each other to Develop and Grow at Novartis. Biopharma Asia https://biopharma-asia.com/featured-careers / also published in Biopharma Careers https://biopharma-careers.com/ .

Spencer, Sarah, Chung, Jessie R., Belongia, Edward A., Sundaram, Maria, Meece, Jennifer, Coleman, Laura A., Zimmerman, Richard K., Nowalk, Mary Patricia, Moehling Geffel, Krissy, Ross, Ted, Carter, Chalise E., Shay, David, Levine, Min, Liepkalns, Justine, Kim, Jin Hyang, Sambhara, Suryaprakash, Thompson, Mark G. and Flannery, Brendan (2022) Impact of diabetes status on immunogenicity of trivalent inactivated influenza vaccine in older adults. Influenza and Other Respiratory Viruses, 16 (3). pp. 562-567. ISSN 1750-2640

Taskar, Kunal, Yang, Xinning, Neuhoff, Sibylle, Patel, Mitesh, Yoshida, Kenta, Paine, Mary, Brouwer, Kim, Chu, Xiaoyan, Sugiyama, Yuichi, Cook, Jack, Polli, Joseph, Hanna, Imad, Lai, Yurong and Zamek-Gliszczynski, Maciej (2022) Clinical relevance of hepatic and renal P-gp/BCRP inhibition of drugs: An International Transporter Consortium perspective. Clinical pharmacology and therapeutics. ISSN 1532-6535

Tassano, Erika, Moore, Charles, Dussauge, Solene, Vargas, Alexandra and Snajdrova, Radka (2022) Discovery of novel Fe(II)/α-ketoglutarate-dependent dioxygenases for oxidation of L-proline. Organic Process Research & Development. ISSN 1083-61601520-586X

Tia , Byer and Richter, Susanne (2022) Future Directions for Accelerated Upstream Bioprocessing. Cell Content hub: https://www.oxfordglobal.co.uk/cell/, n.a. (n.a.). n.a.-n.a.. ISSN n.a.

Tin, Adrienne, Jennings, Lori, Gudnason, Vilmundur and Mosley, Thomas H (2022) Proteomic analysis identifies circulating proteins associated with plasma amyloid βeta and incident dementia. Biological Psychiatry Global Open Science. ISSN 26671743

Tukov, Francis, Mansfield, Keith, Milton, Mark, Meseck, Emily, Penraat, Kelley, Hartmann, Andreas and Chand, Deepa (2022) Single-Dose Intrathecal Dorsal Root Ganglia Toxicity of Onasemnogene Abeparvovec in Cynomolgus Monkeys. Human gene therapy. ISSN 1557-7422

Ullrich, Thomas, Teixeira-Fouchard, Sylvie, Broennimann, Valerie, Stiefl, Nikolaus, Head, Victoria, Kramer, Ina, Guth-Gundel, Sabine, Arista, Luca and Weiler, Sven (2022) Discovery of a novel 2-aminopyrazine-3-carboxamide as a potent and selective inhibitor of Activin Receptor-Like Kinase-2 (ALK2) for the treatment of fibrodysplasia ossificans progressiva. Bioorganic & medicinal chemistry letters. ISSN 1464-3405

Ungricht, Rosemarie, Guibbal, Laure, Lasbennes-Eckerlen, Marie-Christine, Orsini, Vanessa, Beibel, Martin, Waldt, Annick, Cuttat-Theurillat, Rachel, Carbone, Walter, Basler, Anne, Roma, Guglielmo, Nigsch, Florian, Tchorz, Jan, Hoepfner, Dominic and Hoppe, Philipp (2022) Genome-wide screening in human kidney organoids identifies novel aspects of nephrogenesis. Cell stem cell, 29 (1). p. 160. ISSN 19345909

Vulpetti, Anna, Lingel, Andreas, Dalvit, Claudio, Schiering, Nikolaus, Oberer, Lukas, Henry, Christelle and Lu, Yipin (2022) Efficient Screening of Target-Specific Selected Compounds in Mixtures by 19F NMR Binding Assay with Predicted 19F NMR Chemical Shifts. ChemMedChem : chemistry enabling drug discovery. ISSN 1860-7187; 1860-7179

Walles, Markus (2022) A Cross Company Perspective on the Assessment of Therapeutic Protein Biotransformation. Drug metabolism and disposition, June.

Wargenau, Manfred, Reidemeister, Sibylle, Klingmann, Ingrid and Klingmann , Viviane (2022) A composite endpoint for acceptability evaluation of oral drug formulations in the pediatric population. Therapeutic Innovation & Regulatory Science (TIRS) , 2022.

Wilbaux, Melanie, Demanse, David, Gu, Gary, Jullion, Astrid, Myers, Andrea, Katsanou, Vasiliki and Meille, Christophe (2022) Contribution of machine learning to tumor growth inhibition modeling for hepatocellular carcinoma patients under Roblitinib (FGF401) drug treatment. CPT: pharmacometrics & systems pharmacology. ISSN 2163-8306

Wolf, Babette, Piksa, Mateusz, Voedisch, Bernd, Patoux, Agnes, Besson, Thierry, Schindler, Patrick, Cordier, Valerie, Perrot, Ludovic, Brees, Dominique and Kammueller, Michael (2022) Therapeutic antibody glycosylation impacts antigen recognition and immunogenicity. Immunology. ISSN 1365-2567

Zevnik, Branko, Jerchow, Boris and Buch, Thorsten (2022) 3R Measures in facilities for the production of genetically modified rodents. Lab animal, 51 (6). pp. 162-177. ISSN 1548-4475; 0093-7355

de Esch, Iwan J P, Erlanson, Daniel A, Jahnke, Wolfgang, Johnson, Christopher N and Walsh, Louise (2022) Fragment-to-Lead Medicinal Chemistry Publications in 2020. Journal of medicinal chemistry, 65 (1). pp. 84-99. ISSN 1520-4804

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