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Items where Year is 2022

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Number of items: 314.

A

Abdallah, Nasri (2022) People of TM: Video of Nasri Abdallah. YouTube.

Adachi, Yuichiro, Fu, Fumin, Pietropaolo, Michael, Pandit, Shilpa, Li, Weiyan, Murakami, Yutaka, Grewal, Pam, Lussier, Jen, Deyneko, Galina, Turner, Gordon, Shetty, Suraj, Tarnavski, Oleg, Liu, Jing, Cui, Lei, Taggart, Andrew, Waters, Gerry and Coughlin, Shaun (2022) Lack of authentic atrial fibrillation in commonly used murine atrial fibrillation models. PloS one, 17 (1). e0256512. ISSN 1932-6203

Ahire, Deepak, Patel, Mitesh, Deshmukh, Sujal and Prasad, Bhagwat (2022) Quantification of accurate compositions and total abundance of homologous proteins in human tissues using conserved-plus-surrogate peptide (CPSP) approach: Application in the quantification of UDP glucuronosyltransferases. Drug metabolism and disposition. ISSN 1521-009X

Ahmed Madny, Muzaffaruddin, Deshpande, Pandurang, Tumuluri, Sri Venkata, Borde, Parag Prakash and Sangana, Ramachandra (2022) Utilization of in silico tools to investigate the in vivo performance of vildagliptin modified release (MR) 100 mg tablets in healthy subjects using physiologically based biopharmaceutics modeling (PBBM) and evaluate an approach to establish clinically relevant dissolution specifications. AAPS PharmSciTech, 23 (108). pp. 1-17. ISSN 1530-9932

Allmendinger, Thomas, Furet, Pascal, Denay, Regis, Kotoni, Dorina, Bixel, Dominique and Anokwah, Daniel K. (2022) 9-epi-Artemisinin - How a single stereo center affects chemical reactivity and activity. Helvetica Chimica Acta. ISSN 0018-019X1522-2675

Argikar, Upendra, Bednarczyk, Dallas, Cho, Young, Dore, Michael, Jenn, Dumouchel, Ho, Samuel, Hoegenauer, Klemens, Kawanami, Toshio, Mathieu, Simon, Erik, Meredith, Moebitz, Henrik, Stephen, Murphy, Parthasarathy, Van, Pissot Soldermann, Carole, Santos, Jobette, Serena, Silver, Skolnik, Suzanne, Stojanovic, Aleksandar, Chen, Zhuoliang and Blatter, Markus (2022) Paradoxical Increase of Permeability and Lipophilicity with the Increasing Topological Polar Surface Area within a Series of PRMT5 Inhibitors. Journal of medicinal chemistry. ISSN 1520-4804

Auberson, Yves, Lièvre, Akane, Desrayaud, Sandrine and Briard, Emmanuelle (2022) A practical approach to the optimization of positron emission tomography imaging agents for the central nervous system. Journal of labelled compounds & radiopharmaceuticals, 65 (13). pp. 343-350. ISSN 1099-1344

Axelsson, Gisli Thor, Gudmundsson, Gunnar, Aspelund, Thor, Putman, Rachel, Gudmundsson, Elias F, Hatabu, Hiroto, Gudmundsdottir, Valborg, Gudjonsson, Alexander, Launer, Lenore J, Jennings, Lori, Hunninghake, Gary M, Emilsson, Valur and Gudnason, Vilmundur (2022) The Proteomic Profile of Interstitial Lung Abnormalities. American journal of respiratory and critical care medicine. ISSN 1535-4970

B

Badaoui, Magd , Buigues, Pedro J., Berta, Dénes , Mandana, Gaurav M., Kato, Mitsunori, Dickson, Callum, Hornak, Viktor, Molteni, Carla , Parsons, Simon D. and Rosta, Edina (2022) Combined Free-Energy Calculation and Machine Learning Methods for Understanding Ligand Unbinding Kinetics. Journal of chemical theory and computation. ISSN 1549-9626

Badee, Justine Marine (2022) Current Practices, Gap Analysis and Proposed Roadmaps for PBPK Modeling of Cytochrome P450 Induction: An Industry Perspective. CPT: pharmacometrics & systems pharmacology..

Barabas, Amanda J, Darbyshire, Amanda K, Schlegel, Sylvia L and Gaskill, Brianna N (2022) Evaluation of Ambient Sound, Vibration, and Light in Rodent Housing Rooms. Journal of the American Association for Laboratory Animal Science. ISSN 1559-6109

Barabas, Amanda J, Darbyshire, Amanda K, Schlegel, Sylvia L and Gaskill, Brianna N (2022) Evaluation of Ambient Sound, Vibration, and Light in Rodent Housing Rooms. Journal of the American Association for Laboratory Animal Science, 61 (6). pp. 660-671. ISSN 1559-6109

Barabas, Amanda J., Aryal, Uma K. and Gaskill, Brianna N. (2022) Protein profiles from used nesting material, saliva, and urine correspond with social behavior in group housed male mice, Mus musculus. Journal of Proteomics, 266. p. 104685. ISSN 18743919

Barabas, Amanda J., Robbins, Lindsey A. and Gaskill, Brianna N. (2022) Home cage measures of Alzheimer's disease in the rTg4510 mouse model. Genes, Brain and Behavior, 21 (2). ISSN 1601-1848

Barbosa, Ines, Gopalakrishnan, Rajaraman, Mercan, Samuele, Mourikis, Thanos, Martin, Typhaine, Wengert, Simon, Sheng, Caibin, Ji, Fei, Lopes, Rui, Knehr, Judith, Altorfer, Marc, Lindeman, Alicia, Russ, Carsten, Naumann, Ulrike, Golji, Javad, Sprouffske, Kathleen, Barys, Louise, Schmelzle, Tobias and Galli, Giorgio (2022) Large-scale functional epigenomic screens reveal cancer lineage-specific regulation of YAP responsive elements. Nature Communications.

Bassand, C, Benabed, L, Charlon, S, Verin, J, Freitag, J, Siepmann, F, Soulestin, J and Siepmann, J (2022) 3D printed PLGA implants: APF DDM vs. FDM. Journal of controlled release : official journal of the Controlled Release Society. ISSN 1873-4995

Bassand, C., Benabed, L., Freitag, J., Verin, J., Siepmann, F. and Siepmann, J. (2022) How bulk fluid renewal can affect in vitro drug release from PLGA implants: Importance of the experimental set-up. International Journal of Pharmaceutics: X, 4. pp. 50-60. ISSN 25901567

Bassand, C., Benabed, L., Verin, J., Danede, F., Lefol, L.A., Willart, J.F., Siepmann, F. and Siepmann, J. (2022) Hot melt extruded PLGA implants loaded with ibuprofen: How heat exposure alters the physical drug state. Journal of drug delivery science and technology., 73. ISSN 17732247

Bassand, C., Freitag, J., Benabed, L., Verin, J., Siepmann, F. and Siepmann, J. (2022) PLGA implants for controlled drug release: Impact of the diameter. European Journal of Pharmaceutics and Biopharmaceutics, 177. pp. 50-60. ISSN 09396411

Bassand, Celine, Villois, Alessia, Gianola, Lucas, Laue, Grit, Ramazani, Farshad, Riebesehl, Bernd, Sanchez-Felix, Manuel, Ullrich, Thomas, Sedo, Kurt and Duvnjak Romic, Marieta (2022) Smart design of patient centric long-acting products: from preclinical to marketed pipeline trends and opportunities. Expert opinion on drug delivery. ISSN 1744-7593

Bassand, Celine, Verin, Jeremy, Lamatsch, Martin, Siepmann, Florence and Siepmann, Juergen (2022) How agarose gels surrounding PLGA implants limit swelling and slow down drug release. Journal of controlled release : official journal of the Controlled Release Society, 343. pp. 255-266. ISSN 1873-4995

Beauvois, Hugo (2022) Intership report Hugo Beauvois. Thesis submitted at school (Lycée Lavoisier MULHOUSE).

Bechtold-Peters, Karoline, Gervais, Annick, Dirksen, Eef, Lennart, Andrew, Yi, Linda, Burkitt, Will, Cao, Li, D'Alessio, Valerio, Greven, Simone, Lössner, Christopher, Niu, Ben, O'Riordan, Tomas, Reusch, Dietmar, Shearer, Justin, Spencer, David and Xu, Wei (2022) Use of Multi Attribute Method by mass spectrometry as a QC release and stability tool for biopharmaceuticals – Regulatory Considerations. published on EFPIA homepage (see https://www.efpia.eu/publications/), N/A (N/A). N/A. ISSN N/A

Bechtold-Peters, Karoline, Wuchner, Klaus, Yi, Linda, Chery, Cyrille, Junge, Friederike, Crotts, George, Rinaldi, Gianluca, Starkey, Jason, Shumann, Melissa, Leiss, Michael, Jahn, Michael, Garidel, Patrick, De Ruiter, Rien, Richer, Sarah, Cao, Shawn, Peuker, Sebastian, Huille, Sylvain, Wang, Tingting and Le Brun, Virginie (2022) Industry Perspective on the Use and Characterization of Polysorbates for Biopharmaceutical Products Part 2: Survey Report on Control Strategy Preparing for the Future. Journal of pharmaceutical sciences, 111 (11). pp. 2955-2967. ISSN 1520-6017

Bechtold-Peters, Karoline (2022) Industry Perspective on the use and Characterization of Polysorbates for Biopharmaceutical Products Part 1: Survey Report on Current State and Common Practices for Handling and Control of Polysorbates. Journal of pharmaceutical sciences, 111 (5). pp. 1280-1291. ISSN 00223549

Bechtold-Peters, Karoline, Paboojian, Stephen and Weikart, Christopher (2022) Improved Drug Stability Stored in Lubricant-Free Hybrid Syringes. American pharmaceutical review, 25 (4 (May). ISSN 10998012

Beckers, Maximilian, Fechner, Nikolas and Stiefl, Nikolaus (2022) 25 Years of Small-Molecule Optimization at Novartis: A Retrospective Analysis of Chemical Series Evolution. Journal of chemical information and modeling, 62 (23). pp. 6002-6021. ISSN 1549-960X

Beckers, Maximilian, Fechner, Nikolas and Stiefl, Nikolaus (2022) Cover art to "25 years of small molecule optimization at Novartis: A retrospective analysis of chemical series evolution". Journal of chemical information and modeling, 62 (23). pp. 5849-6286.

Beckmann, Nicolau (2022) Editorial for "Impact of Dynamic Contrast Enhanced and Diffusion-Weighted MR Imaging on Detection of Early Local Recurrence of Soft Tissue Sarcoma”. Journal of magnetic resonance imaging, 57 (2). pp. 631-632. ISSN doi: 10.1002/jmri.28295

Beckmann, Nicolau (2022) Editorial for "Evaluation of Dynamic Contrast-Enhanced MRI Measures of Lung Congestion and Endothelial Permeability in Heart Failure: A Prospective Method Validation Study”. Journal of Magnetic Resonance Imaging. ISSN 1053-18071522-2586

Benito-Villalvilla, Cristina, de la Rocha-Munoz, Andres, Lopez-Abente, Jacobo, Eggel, Alexander, Bottoli, Ivan, Severin, Thomas, Woisetschlaeger, Maximilian and Palomares, Oscar (2022) Ligelizumab impairs IgE-binding to plasmacytoid dendritic cells more potently than omalizumab and restores IFN-α production and FOXP3+ Treg generation. Allergy. ISSN 1398-9995

Berghausen, Joerg, Petersson, Carl, Zhou, Xin, Cebrian, Brian, Davies, Michael, DeMent, Kevin, Eddershaw, Peter, Emami Riedmaier, Arian, Leblanc, Alix, Manveski, Nenad, Marathe, Punit, Mavroudis, Panteleimon, McDougall, Robin, Parrott, Neil, Reichel, Andreas, Rotter, Charles, Tess, David, Volak, Laurie, Xiao, Guangqing, Yang, Zhen and Baker, James (2022) Current approaches for predicting human PK for small molecule development candidates: Findings from the IQ Human PK Prediction Working Group Survey. The AAPS journal.

Betschart, Claudia, Faller, Michael, Zink, Florence, Hemmig, Rene, Blank, Jutta, Vangrevelinghe, Eric, Bourrel, Marjorie, Glatthar, Ralf, Behnke, Dirk, Barker, Kerstin, Heizmann, Andreas, Angst, Daniela, Nimsgern, Pierre, Jacquier, Sebastien, Junt, Tobias, Collignon Zipfel, Geraldine, Ruzzante, Giulia, Loetscher, Pius, Limonta, Sarah, Hawtin, Stuart, Andre, Cedric Bernard, Boulay, Thomas, Feifel, Roland and Knoepfel, Thomas (2022) Structure-based optimization of a fragment like TLR8 binding screening hit to an in vivo efficacious TLR7/8 antagonist. ACS Medicinal Chemistry Letters. ISSN 1948-58751948-5875

Bluemel, Oliver, Friess, Wolfgang, Rodrigues, Miguel, Geraldes, Vitor, Pavlišič, Andraž, Likozar, Blaž and Bechtold-Peters, Karoline (2022) Computational fluid dynamic simulations of temperature, cryoconcentration, and stress time during large-scale freezing and thawing of monoclonal antibody solutions. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 177. pp. 107-112. ISSN 1873-3441

Bluemel, Oliver, Bechtold-Peters, Karoline, Anuschek, Moritz, Buecheler, Jakob, Hoelzl, Georg and Friess, Wolfgang (2022) The effect of mAb and excipient cryoconcentration on long-term frozen storage stability - Part 1: Higher molecular weight species and subvisible particle formation. International journal of pharmaceutics: X, 4. p. 100108. ISSN 2590-1567

Bluemel, Oliver, Buecheler, Jakob, Hauptmann, Astrid, Hoelzl, Georg, Bechtold-Peters, Karoline and Friess, Wolfgang (2022) The effect of mAb and excipient cryoconcentration on long-term frozen storage stability - part 2: Aggregate formation and oxidation. International journal of pharmaceutics: X, 4. p. 100109. ISSN 2590-1567

Bluemel, Oliver, Friess, Wolfgang, Rodrigues, Miguel, Geraldes, Vitor, Bechtold-Peters, Karoline, Buecheler, Jakob, Hauptmann, Astrid and Hoelzl, Georg (2022) Evaluation of Two Novel Scale-Down Devices for Testing Monoclonal Antibody Aggregation During Large-Scale Freezing. Journal of pharmaceutical sciences. ISSN 1520-6017

Blume, T, Filser, SS, Sgobo, C, Peters, F, Neumann, Ulf, Shimshek, Derya, Saito, T, Saido, T, Brendel, M and Herms, J (2022) β‐secretase inhibition prevents structural spine plasticity deficits in App NL-G-F mice. Frontiers in aging neuroscience., 14. ISSN 1663-4365

Boesch, Julian, Pierrel, Eliane, Lambert, Christian, Doelemeyer, Arno, Kreider, Julie, Accart Gris, Nathalie and Summermatter, Serge (2022) Chemokine-like receptor 1 plays a critical role in modulating the regenerative and contractile properties of muscle tissue. Frontiers in physiology, 13. p. 1044488. ISSN 1664-042X

Bolon, Brad, Francke, Sabine, Caverly Rae, Jessica M., Polack, Evelyne, Regan, Karen S., McInnes, Elizabeth F., Romeike, Annette, Young, Jamie K., Colman, Karyn, Keane, Kevin, Perry, Rick, Jensen, Karl, Nakano-Ito, Kyoko and Galbreath, Elizabeth J. (2022) Scientific and Regulatory Policy Committee Best Practices: Recommended ("Best") Practices for Informed (Non-blinded) Versus Masked (Blinded) Microscopic Evaluation in Animal Toxicity Studies. Toxicologic pathology, 50 (8). pp. 930-941. ISSN 1533-1601

Bondeson, Daniel, Tothova, Zuzana, Golub, Todd, Sellers, William and Ianari, Alessandra (2022) Systematic profiling of conditional degron tag technologies for target validation studies. Nature communications, 13 (1). p. 5495. ISSN 2041-1723

Bonhoeffer, Bastian, Kordikowski, Andreas, John, Edgar and Juhnke, Michael (2022) Numerical modelling of the dissolution of drug nanocrystals and its application to industrial product development. ADMET and DMPK. ISSN 1848-7718

Borsari, Chiara, Matagne, Brieuc, Goncharenko, Kristina, Moreira, Rui and Auberson, Yves (2022) The Facets of Diversity: The EFMC Perspective. ChemMedChem. e202200245. ISSN 1860-7187

Boulton, Craig (2022) People of TM: Video of Craig Boulton. LinkedIn & Youtube.

Bower, Nancy, Achanzar, William E., Boulifard, Virginie, Brink, Peter R., Kittel, Birgit and Vahle, John L. (2022) The Dog as a Second Species for Toxicology Testing Provides Value to Drug Development. International journal of toxicology. p. 10915818221125670. ISSN 1092-874X

Bowman, Christopher, Barrow, Paul, Erkman, Linda and Muller, Mireille (2022) Science-based approach to harmonize contraception recommendations in clinical trials and pharmaceutical labels. Clinical pharmacology and therapeutics. ISSN 1532-6535

Bray, Mark, Durand, Eric, de Weck, Antoine, Fang, Jian, Gabriel, Daniela, Janssens, Rens, Moutsatsos, Ioannis, Spiegel, Stephan and Zhang, Xian (2022) High-content cellular screen image analysis benchmark study. bioRxiv.

Bray, Mark, Durand, Eric, de Weck, Antoine, Fang, Jian, Gabriel, Daniela, Janssens, Rens, Moutsatsos, Ioannis, Spiegel, Stephan and Zhang, Xian (2022) High-content cellular screen image analysis benchmark study. bioRxiv.

Breustedt, Daniel (2022) Interpharma-Interview on surplus animals in transgenics breeding. Interpharma 3R report, n.a. (n.a.). n.a.-n.a.. ISSN n.a.

Brosig, Sebastian, Buecheler, Jakob, Chou, Danny, Christian, Twinkle, Das, Tapan, De Jong, Isabella, Fast, Jonas, Jagannathan, Bharat, Medina, Annette, Moussa, Ehab, Prajapati, Indira, Radwick, Allison and Singh, Shubhadra (2022) End-to-End Approach to Surfactant Selection, Risk Mitigation, and Control Strategies for Protein-Based Therapeutics. The AAPS journal, 25 (1). p. 6. ISSN 1550-7416

Bruin, Gerardus and Walles, Markus (2022) Absorption, Distribution, Metabolism, and Excretion (ADME) of Therapeutic Proteins: A White Paper on Current Industry Practices and Future Perspectives. Drug metabolism and disposition. ISSN doi: 10.1124/dmd.121.000461

Buller, Rebecca, Snajdrova, Radka and Moore, Charles (2022) Bioinformatic Toolbox for the Development of novel CH-Activation Biocatalysts (CH-Pred). Innosuisse Grant Submission.

Bunc, Marko, Boncina, Matjaz, Graf, Christian, Hadži , San and Lah, Jurij (2022) Aggregation Time Machine: A Platform for the Prediction and Optimization of Long-Term Antibody Stability Using Short-Term Kinetic Analysis. Journal of Medicinal Chemistry, 65 (3). pp. 2623-2632. ISSN 0022-26231520-4804

Byrd, Christopher J, McConn, Betty R, Gaskill, Brianna N, Schinckel, Allan P, Green-Miller, Angela R, Lay, Donald C and Johnson, Jay S (2022) Characterizing the effect of incrementally increasing dry bulb temperature on linear and nonlinear measures of heart rate variability in nonpregnant, mid-gestation, and late-gestation sows. Journal of Animal Science, 100 (1). ISSN 0021-8812

Böttinger, Katharina, Paul, Katrin, Esser-Skala, Wolfgang, Segl, Marius, Herwig, Christoph and Huber, Christian (2022) At-line quantitative profiling of monoclonal antibody products during bioprocessing using HPLC-MS. Analytica chimica acta, 1207. p. 339813. ISSN 1873-4324

C

Calonder, Claudio, Lotz, Gregor, Benstein, Karin, Bloem, Karien, Buddinger, Harm, Elm, Stefanie, Fernandez, Elena, Gorovits, Boris, Grudzinska-Goebel, Joanna, Janssen, Melody, Jawa, Vibha, Luo, LinLin, Malisauskas, Mantas, Michaut, Lydia, Schäfer, Martin, Spindeldreher, Sebastian, Ullmann, Martin, Weldingh, Karin Nana, Kromminga, Arno, Snoeck, Veerle, Kramer, Daniel and Joanne, Goodman (2022) When to Extend Monitoring of Anti-drug Antibodies for High-risk Biotherapeutics in Clinical Trials: an Opinion from the European Immunogenicity Platform. The AAPS journal, 24 (3). p. 68. ISSN 1550-7416

Casado-García, Ana, Isidro-Hernández, Marta , Oak, Ninad, Mayado, Andrea , Mann-Ran, Christine, Raboso-Gallego, Javier , Alemán-Artega, Silvia , Buhles, Alexandra, Sterker, Dario, Blanco, Oscar, Orfao, Alberto, Alonso-López, Diego, De Las Rivas, Javier, Riesco, Susana, Prieto-Matos, Pablo, Criado, Francisco Javier García, Cenador, María Begoña García, Radimerski, Thomas, Ramírez-Orellana, Manuel, Cobaleda, César, Yang, Jun J, Vicente-Dueñas, Carolina, Weiss, Andreas, Nichols, Kim E and Sánchez-García, Isidro (2022) Transient JAK/STAT pathway inhibition prevents natural occurring B-ALL development in genetically predisposed Pax5+/- mice. Cancer research, Epub a (canres). ISSN 1538-7445; 0008-5472

Chan, Jason, Allen, Richard, Boras, Britton, Cabal, Antonio, Damian, Valeriu, Gibbons, Francis, Gulati, Abhishek, Hosseini, Iraj, Kearns, Jeff, Ryuuta, Saitou, Cucurull-Sanchez, Lourdes, Selimkhanov, Jangir, Stein, Andrew, Umehara, Kenichi, Wang, Guanyu, Wang, Weirong and Neves-Zaph, Susana (2022) Current practices for QSP model assessment: an IQ consortium survey. Journal of pharmacokinetics and pharmacodynamics. ISSN 1573-8744

Charmont, Stephane, Sangana, Ramachandra and Valentin, Marie-Anne (2022) Development, validation and application of a liquid chromatography-tandem mass spectrometry method for the activity and inhibition of DPP-4. Bioanalysis, 14 (6). pp. 369-378. ISSN 1757-6199

Chen, Jin, Gu, Jessie, Shah, Bharti, Stringer, Rowan, Reis da Silva Torrao, Leonel, Hackling, Melissa, Nidamarthy, Prasanna, Prince, William and Woessner, Ralph (2022) Pharmacokinetics of Tropifexor, a Potent Farnesoid X Receptor Agonist, in Participants With Varying Degrees of Hepatic Impairment. Journal of clinical pharmacology, 62 (4). pp. 520-531. ISSN 1552-4604

Clark, Kirk, Kulathila, Raviraj, Wright, Kirk, Isome, Yuko, Sage, David, Yang, Yi and Christodoulou, Constantina (2022) Crystal structure of 2-PG bound to BPGM. RCSB Protein Data Bank.

Clarke, Adrian and Stoll, Dwight (2022) Analytically-speaking-podcast podcast "sometimes negative results turn out to be the most interesting ones": Adrian Clarke interviewed by Dwight Stoll. LC-GC europe : Solutions for Separation Scientists..

Combes, Francois Pierre, Li, Ying fei, Hoch, Matthias, Lorenzo, Sebastien, Ho, Yu-Yun and Sy, Sherwin (2022) Exposure-Efficacy Analysis of Asciminib in Philadelphia Chromosome-Positive Chronic Myeloid Leukemia in Chronic Phase. Clinical pharmacology and therapeutics, 112 (5). pp. 1040-1050. ISSN 1532-6535

Connelly, Kim A, Wu, Ellen, Visram, Aylin, Friedberg, Mark K, Batchu, Sri Nagarjun, Yerra, Veera Ganesh, Thai, Kerri, Nghiem, Linda, Zhang, Yanling, Kabir, Golam, Desjardins, J F, Advani, Andrew and Gilbert, Richard E (2022) The SGLT2i dapagliflozin reduces RV mass independent of changes in RV pressure induced by pulmonary artery banding. Cardiovascular drugs and therapy. ISSN 1573-7241

Cortopassi, Wilian A., Gunderson, Emma, Annunciato, Yasmin, Silva, Antony.E.S., dos Santos Ferreira, Amália, Garcia Teles, Carolina Bioni, Pimentel, Andre S., Ramamoorthi, Roopa, Gazarini, Marcos, Meneghetti, Mario R., Guido, Rafael.V.C., Pereira, Dhelio B., Jacobson, Matthew P., Krettli, Antoniana U. and Caroline C Aguiar, Anna (2022) Fighting Plasmodium chloroquine resistance with acetylenic chloroquine analogues. International Journal for Parasitology: Drugs and Drug Resistance. ISSN 22113207

Crowley, Maura, Garland, Donita, Sellner, Holger, Banks, Angela, Rejtar, Tomas, Buchanan, Natasha, Delgado, Omar, Xu, YongYao, Adams, Christopher, Mogi, Muneto, Bigelow, Chad, Poor, Stephen, Anderson, Karen, Jaffee, Bruce, Prasanna, Ganesh, Grosskreutz, Cyndy, Feenandez-Godino, Rosario, Pierce, Eric, Dryja, Thaddeus and Liao, Sha-Mei (2022) Complement factor B is critical for sub-RPE deposit formation in a model of DHRD/ML with features of age-related macular degeneration. Human molecular genetics.

Cvetkoska, Aleksandra, Dermol-Cerne, Janja, Miklavčič, Damijan, Kranjc Brezar, Simona, Markelc, Boštjan, Serša, Gregor and Reberšek, Matej (2022) Design, Development, and Testing of a Device for Gene Electrotransfer to Skin Cells In Vivo. Pharmaceutics, 14 (9). p. 1826. ISSN 1999-4923

D

Dalvit, Claudio, Veronesi, Marina and Vulpetti, Anna (2022) 1H and 19F NMR chemical shifts for hydrogen bond strength determination: Correlations between experimental and computed values. Journal of Magnetic Resonance Open, 12-13. ISSN 26664410

Dartee, Wim and Hernandez Penna, Sabina (2022) ON THE USE OF WEARABLE SENSORS AS MOBILITY BIOMARKERS IN THE MARKETING AUTHORISATION OF NEW DRUGS: A REGULATORY PERSPECTIVE. Frontiers in Medicine.

Davis, Haley J., Barabas, Amanda J. and Gaskill, Brianna N. (2022) Titrating the preferences of altered lighting against temperature in female CD-1 laboratory mice, Mus musculus. Applied Animal Behaviour Science, 246. p. 105541. ISSN 01681591

Davis, John, Kulmatycki, Ken, Humphries, Sara C, Iqbal, Sajida, Kamel, Amin, Lao, Yanbin, Liu, Xiumin, Rogers , John, Snoeys, Jan, Weng, Yan, Vigil, Adam, Wiethoft, Christopher M and Wittwer, Matthias B (2022) Considerations and recommendations for assessment of plasma protein binding and drug-drug interactions for siRNA therapeutics. Nucleic acids research, 50 (11). pp. 6020-6037.

Dawson King, Janet, Accart Gris, Nathalie, Obrecht, Michael, Lambert, Christian, Flueckiger, Manuela, Kreider, Julie, Hatakeyama, Shinji, Richards, Peter and Beckmann, Nicolau (2022) Degenerative joint disease induced by repeated intra-articular injections of monosodium urate crystals in rats as investigated by translational imaging. Scientific reports, 12 (1). p. 157. ISSN 2045-2322

De Luca, Valeria (2022) People of TM: Video of Valeria de Luca. LinkedIn & YouTube.

De Luca, Valeria (2022) Measuring Health-Related Quality of Life With Multimodal Data: Viewpoint. Journal of medical internet research, 24 (5). ISSN 1438-8871

Demanse, David, Saxer, Franziska, Lustenberger, Patrick, Tanko, Laszlo, Nikolaus, Philipp, Rasin, Ilja, Brennan, Damian, Roubenoff, Ronenn, Premji, Sumehra, Conaghan, Philip and Schieker, Matthias (2022) Unsupervised machine-learning algorithms for the identification of clinical phenotypes in the osteoarthritis initiative database. Seminars in arthritis and rheumatism, 58. p. 152140. ISSN 1532-866X

Devaraj, Sankarganesh, Barabas, Amanda J., Soini, Helena A., Novotny, Milos V., Lucas, Jeffrey R., Erasmus, Marisa A., Cheng, Heng-Wei, Palme, Rupert and Gaskill, Brianna N. (2022) Assessing the effect of compounds from plantar foot sweat, nesting material, and urine on social behavior in male mice, Mus musculus. PLOS ONE, 17 (11). e0276844. ISSN 1932-6203

Dhandapani, Rahul, Neri, Marilisa, Bernhard, Mario, Brzak, Irena, Schweizer, Tatjana, Rudin, Stefan, Stefanie, Joller, Berth, Ramon, Kernen, Jasmin, Neuhaus, Anna, Waldt, Annick, Cuttat-Theurillat, Rachel, Naumann, Ulrike, Gubser Keller, Caroline, Roma, Guglielmo, Feuerbach, Dominik, Shimshek, Derya, Ulf, Neumann, Gasparini, Fabrizio and Galimberti, Ivan (2022) Sustained Trem2 stabilization accelerates microglia heterogeneity and Aβ pathology in a mouse model of Alzheimer’s disease. Cell reports, 39 (9). ISSN 2211-1247

DiDominick, Sarah, Abozeid, Ahmed M, Chen, Xueying, Stammberger, Uz, Santoro, Armando, Su, Wu-Chou, Navarro, Alejandro, Simonelli, Matteo, Yang, James CH, Ardizzoni, Andrea, Barlesi, Fabrice, Kang, Jin Hyoung and Felip, Enriqueta (2022) Phase Ib/II study of ceritinib in combination with ribociclib in patients with ALK-rearranged non-small cell lung cancer. Lung cancer (Amsterdam, Netherlands), 166. pp. 170-177. ISSN 1872-8332

Dickson, Callum, Walker, Ross and Gould, Ian (2022) Lipid21: Complex Lipid Membrane Simulations with AMBER. Journal of chemical theory and computation. ISSN 1549-9626

Dillon, Noah, Cocanougher, Ben, Sood, Chhavi, Yuan, Xin, Kohn, Andrea B, Moroz, Leonid L, Siegrist, Sarah E, Zlatic, Marta and Doe, Chris Q. (2022) Single cell RNA-seq analysis reveals temporally-regulated and quiescence-regulated gene expression in Drosophila larval neuroblasts. Neural Development, 17 (1). ISSN 1749-8104

Dimitrieva Janeva, Slavica, Janssens, Rens, Li, Gang, Szalata, Artur, Gopal, Raja, Parmar, Chintan, Kauffmann, Audrey and Durand, Eric (2022) Biologically relevant integration of transcriptomics profiles from cancer cell lines, patient derived xenografts and patient tumors using deep neural networks. bioRxiv.

Duca, Matteo, Lim, Darren Wan-Teck , Subbiah, Vivek, Takahashi, Shunji, Sarantopoulos, John, Varga, Andrea, D'Alessio, Tony, Abrams, Tinya, Sheng, Qing, Tan, Eugene, Cintrao Dos Santos Rosa, Maria, Gonzalez Maffe, Juan, Sand Dejmek, Janna, Fabre, Claire and Martin, Miguel (2022) A First-in-Human, Phase 1, Multicenter, Open-label, Dose-Escalation Study of PCA062, an Antibody-Drug Conjugate Targeting P-Cadherin, in Adult Patients with Solid Tumors. Molecular cancer therapeutics, 21 (4). pp. 625-634. ISSN 1535-7163

Dunn, Allison, Jung, Dawoon, Bollinger, Lisa, Krams, Michael, Smith, Brian and Gobburu, Jogarao (2022) Accelerating Availability of Medicines to Pediatrics via Extrapolation of Efficacy from Adults. Therapeutic Innovation & Regulatory Science, 56 (6). pp. 873-882. ISSN 2168-4790

de Esch, Iwan J P, Erlanson, Daniel A, Jahnke, Wolfgang, Johnson, Christopher N and Walsh, Louise (2022) Fragment-to-Lead Medicinal Chemistry Publications in 2020. Journal of medicinal chemistry, 65 (1). pp. 84-99. ISSN 1520-4804

E

Ebersbach, Hilmar, Jascur, Julia, Keshvari, Sahar, Genz, Berit, Teakle, Ngari, Caruso, Melanie, Cestari, Michele F, Patkar, Omkar L, Tse, Brian WC, Sokolowski, Kamil A, MacDonald, Kelly P.A., Miller, Gregory, Ramm, Grant A, Pettit, Allison R, Clouston, Andrew D, Powell, Elizabeth E, Hume, David A and Irvine, Katharine M (2022) Therapeutic potential of macrophage colony-stimulating factor (CSF1) in chronic liver disease. Disease models & mechanisms. ISSN 1754-8411

Eichler, Gabriel, Imbert, Georges, Branson, Janice, Balibey, Rene, Laramie, Jason, Hersch, Greg, Askin, Scott, Kauffmann, Audrey, Speyer, Peter, Cochrane, Andrew, Mannan, Haripriya, Rudolph, Amy, Asakiewicz, Christopher, McGovern, Patricia, Ramanathan, Krishnan and Ballard, Mary (2022) Democratizing data at Novartis through clinical trial data access. Drug discovery today. ISSN 1878-5832

Elez, Elena, Ros, Javi, Fernandez, Jose, Villacampa, Guillermo, Kodack, David, Moreno, Ana Belen, Arenillas, Carlota, Li, Shanshan, Dienstmann, Rodrigo, Bernatowicz, Kinga, Fasani, Roberta, Comas, Raquel, Garcia, Ariadna, Gonzalez-Ruiz, Javi, Piris-Gimenez, Alejandro, Nuciforo, Paolo, Perez-Lopez, Raquel, Vivancos, Ana, Smits, Ron, Randon, Giovanni, Graus-Porta, Diana, Cremolini, Chiara, Lonardi, Sara, Pietrantonio, Filippo, Tabernero, Josep, Toledo, Rodrigo, Kerr, Grainne, Montagna, Aldo, Germani, Marco Maria and Intini, Rossana (2022) RNF43 mutations predict response to anti-BRAF/EGFR combinatory therapies in BRAFV600E metastatic colorectal cancer. Nature medicine, 28 (10). pp. 2162-2170. ISSN 1546-170X; 1078-8956

Emilsson, Valur, Gudmundsson, Elias, Jonmundsson, Thorarinn, Twarog, Michael, Gudmundsdottir, Valborg, Finkel, Nancy, Poor, Stephen, Liu, Xin, Esterberg, Robert, Zhang, Yiyun, Grosskreutz, Cyndy, Nguyen, Andrew, Huang, Qian, Leehy, Barrett, Pitts, Rebecca, Jonsson, Brynjolfur, Aspelund, Thor, Lamb, John, Jonasson, Fridbert, Launer, Lenore, Frances Cotch, Mary, Jennings, Lori, Gudnason, Vilmundur and Walshe, Tony (2022) A proteogenomic signature of age-related macular degeneration in blood. Nature communications, 13 (1). p. 3401. ISSN 2041-1723

Ertl, Peter (2022) Magic Rings: Navigation in the Ring Chemical Space Guided by the Bioactive Rings. Journal of chemical information and modeling, 62 (9). pp. 2164-2170. ISSN 1549-960X

Ertl, Peter (2022) Substituents of life: The most common substituent patterns present in natural products. Bioorganic & medicinal chemistry, 54. p. 116562. ISSN 1464-3391

Ertl, Peter (2022) A Web Tool for Calculating Substituent Descriptors Compatible with Hammett Sigma Constants. Chemistry–Methods (e20220). pp. 1-6. ISSN 2628-97252628-9725

Ertl, Peter, Altmann, Eva, Racine, Sophie and Lewis, Richard (2022) Ring replacement recommender: Ring modifications for improving biological activity. European journal of medicinal chemistry, 238. p. 114483. ISSN 1768-3254

Ertl, Peter, Altmann, Eva, Racine, Sophie and Lewis, Richard (2022) Ring replacement recommender: Ring modifications that lead consistently to improved biological activity. European Journal of medicinal chemistry, 238 (114483).

F

Fairhurst, Robin, Caravatti, Giorgio, Furet, Pascal, Imbach-Weese, Patricia, Stauffer, Frederic, Rueeger, Heinrich, Mccarthy, Clive, Ripoche, Sebastien, Oswald, Susanne, Arnaud, Bertrand, Jary, Aline, Maira, Michel, Schnell, Christian, Guthy, Daniel Alexander, Wartmann, Markus, Kiffe, Michael, Desrayaud, Sandrine, Blasco, Francesca, Widmer, Toni, Seiler, Frank Hans, Gutmann, Sascha and Knapp, Mark (2022) Identification of NVP-CLR457 as an Orally Bioavailable Non-CNS-Penetrant pan-Class IA Phosphoinositol-3-Kinase Inhibitor. Journal of medicinal chemistry, 65 (12). pp. 8345-8379. ISSN 1520-4804

Fichter, Marie, Richter, Gesa, Bepperling, Alexander and Wassmann, Paul (2022) Pre-clinical in-vitro studies on parameters governing immune complex formation. Pharmaceutics.

Figuccia, Aude, Borths, Christopher, Burr, Tracey, Ford, J Gair, Guan, Bing, Jones, Michael, Klingeleers, Didier, Lochner, Susanne, Rodriguez, Andrew and Wetter, Christian (2022) Nitrosamine Risk Assessments in Oligonucleotides. Organic Process Research & Development. ISSN 1083-61601520-586X

Flandre, Thierry, Mansfield, Keith, Espie, Pascal, Rubic-Schneider, Tina and Ulrich, Peter (2022) Immunosuppression Profile of CFZ533 (Iscalimab), a Non-Depleting Anti-CD40 Antibody, and the Presence of Opportunistic Infections in a Rhesus Monkey Toxicology Study. Toxicologic pathology. pp. 1-13.

Flynn, Julia, Samant, Neha, Schneider-Nachum, Gily, Barkan, Dave, Moquin, Stephanie, Dovala, Dustin, Schiffer, Celia and Bolon, Daniel (2022) Comprehensive fitness landscape of SARS-CoV-2 Mpro reveals insights into viral resistance mechanisms. eLife, 11. ISSN 2050-084X

Forest, Thomas, Aeffner, Famke, Bangari, Dinesh, Bawa, Bhupinder, Carter, Jonathan, Fikes, James, HIgh, Wanda, Hayashi, Shim-mo, Jacobsen, Matthew, McKinney, LuAnn, Rudmann, Daniel, Steinbach, Thomas, Vanessa, Schumacher, Turner, Oliver, Ward, Jerrold and Willson, Cynthia (2022) Scientific and Regulatory Policy Committee (SRPC): 2019 Survey on Use of Digital Histopathology Systems in Nonclinical Toxicology Studies. Toxicologic pathology, 50 (3).

Forest, Thomas, Aeffner, Famke, Bangari, Dinesh, Bawa, Bhupinder, Carter, Jonathan, Fikes, James, High, Wanda, Hayashi, Shim-mo, Jacobsen, Matthew, McKinney, LuAnn, Rudmann, Daniel, Steinbach, Thomas, Schumacher, Vanessa, Turner, Oliver, Ward, Jerrold and Willson, Cynthia (2022) Scientific and Regulatory Policy Committee Points to Consider*: Primary Digital Histopathology Evaluation and Peer Review for Good Laboratory Practice (GLP) Nonclinical Toxicology Studies. Toxicologic pathology.

Francotte, Eric and Huynh, Dan (2022) Immobilization of 3,5-Dimethylphenyl Carbamate of Cellulose and Amylose on Silica by Photochemical and Thermal Radical Processes. Immobilization of 3,5-dimethylphenyl carbamate of cellulose and amylose on silica by photochemical and thermal radical processes, 2022. pp. 1-21. ISSN 1520-636X

Freedman, Benjamin R, Mooney, David J and Weber, Eckhard (2022) Advances toward transformative therapies for tendon diseases. Science translational medicine, 14 (661). eabl8814. ISSN 1946-6242

Freedman, Benjamin R, Kuttler, Andreas, Beckmann, Nicolau, Nam, Sungmin, Kent, Daniel, Farshad, Ramazani, Schuleit, Michael, Accart Gris, Nathalie, Rock, Anna, Li, Jianyu, Kurz, Markus, Fisch, Andreas, Ullrich, Thomas, Hast, Michael W, Tinguely, Yann , Weber, Eckhard and Mooney, David J (2022) Enhanced tendon healing by a tough hydrogel with an adhesive side and high drug-loading capacity. Nature Biomedical Engineering.

G

Gallou, Fabrice (2022) Allylations of Aryl/Heteroaryl Ketones: Neat, Clean, and Green. Applications to Targets in the Pharma- and Nutraceutical Industries. Green chemistry, 24. pp. 4909-4914.

Gallou, Fabrice (2022) Aqueous Micelle-Driven Spontaneously Formed Ligand-Free Pal-ladium(0) Nanoparticles are Efficient Catalyst for Cross-Couplings Enabling Biaryl Ketones. ACS Appl. Mater. Interfaces, 14. p. 50947.

Gallou, Fabrice (2022) Impact of Aqueous Micellar Media on Biocatalytic Transformations Involving Transaminase (ATA); Applications to Chemoenzymatic Catalysis. Green chemistry, 24. pp. 6172-6178. ISSN 1463-9270; 1463-9262

Gallou, Fabrice (2022) Passivation Effect of Micelles on [Ni-Co] Bimetallic Nanosheets for (Z)-Selective Semihydrogenation of Alkynes Using Water as the Hydrogen Source. ACS Appl. Mater. Interfaces, 14 (5). pp. 6754-6761.

Gallou, Fabrice and Wu, Bin (2022) Nanoparticules and their impact in the chemistry of interface-rich aqueous systems. current opinion in green and sustainable chemistry, 38. p. 100691.

Gallou, Fabrice (2022) The Catalytic Formation of Atropisomers and New Stereocenters via Asymmetric Suzuki-Miyaura Couplings. ACS catalysis, 12 (9). pp. 4918-4937.

Gallou, Fabrice (2022) Phosphine Ligand-Free Bimetallic Ni(0)Pd(0) Nanoparticles as a Catalyst for Facile, General, Sustainable, and Highly Selective 1,4-Reductions in Aqueous Micelles. ACS Appl. Mater. Interfaces, 14 (5). pp. 6754-6761.

Gallou, Fabrice (2022) Selectivity Arising from Synergy Between Two Metals and Aqueous Micelle: Nickel-Palladium Bimetallic Nanoparticles for Facile and Highly Selective 1,4-Reduction of Chalcones. ACS Appl. Mater. Interfaces, 14 (5). pp. 6754-6761.

Gallou, Fabrice (2022) Sustainable and Bench-Stable Photoactive Aqueous Nanoaggregates of Cu(II) for ppm Cu(I) Catalysis in Water. Advanced materials.

Gallou, Fabrice (2022) Water: An Underestimated Solvent for Amide Bond-Forming Reactions. ACS Sustainable Chemistry & Engineering, 10 (16). pp. 5299-5306.

Gallou, Fabrice, Grandeury, Arnaud and Jones, Graham (2022) Cultural Diversity Drives Innovation: Does Institutional Residence Time Impact Behaviors? Journal of Innovation Management, 9 (9). pp. 1-9. ISSN 2183-0606

Garcia, Francisco, Hoopes, Caleb, Sarkar, Akash, Kuehl, Nicholas, Barkan, Dave, Collins, Nicole, Bramhall, Taylor, Meister, Glenna, Hsu, Chien-Hsiang, Jones, Michael, Schirle, Markus and Taylor, Michael (2022) Donor-Acceptor Pyridinium Salts for Photo-Induced Electron-Transfer-Driven Modification of Tryptophan in Peptides, Proteins, and Proteomes Using Visible Light. Journal of the American Chemical Society. ISSN 1520-5126

Garcia, Francisco, Hoopes, Caleb, Sarkar, Akash, Kuehl, Nicholas, Barkan, Dave, Collins, Nicole, Meister, Glenna, Bramhall, Taylor, Hsu, Chien-Hsiang, Jones, Michael, Schirle, Markus and Taylor, Michael (2022) Donor-Acceptor Pyridinium Salts for Photo-Induced Electron-Transfer-Driven Modification of Tryptophan in Peptides, Proteins, and Proteomes Using Visible Light. Journal of the American Chemical Society, 144 (14). pp. 6227-6236. ISSN 1520-5126

Garfall, Alfred, Cohen, Adam, Susanibar-Adaniya, Sandra, Vogl, Dan, Waxman, Adam, Lacey, Simon, Vanessa, Gonzalez, Gupta, Minnal, Kulikovskaya, Irina, Tian, Lifeng, Chen, Fang, Koterba, Natalka, Bartoszek, Chelsie, Plesa, Gabriela, Siegel, Donald, Brennan, Andrea, Nelson, Anne Marie, Ferthio, Regina, Cosey, Angela, Shea, Kim-Marie, Leskowitz, Rachel, Four, Megan, Wilson, Wesley, Miao, Fei, Eric, Lancaster, Carreno, Beatriz, Linette, Gerald, Hexner, Elizabeth, Young, Regina, Bu, Dexiu, Mansfield, Keith, Brogdon, Jennifer, June, Carl, Huang, Wei-Ting, Milone, Michael and Edward, Stadtmauer (2022) CAR T cells targeting BCMA and CD19 for newly diagnosed and relapsed multiple myeloma patients responding to current therapy. Blood Cancer Discovery.

Gerebtzoff, Gregori (2022) People of TM: Video Gregori Gerebtzoff. YouTube.

Glinsek, Katja, Kramer, Lovro, Krajnc, Aleksander, Kranjc, Eva, Pirher, Nina, Marusic, Jaka, Hellmann, Leon, Podobnik, Barbara, Strukelj, Borut, Auslaender, David Sebastian and Gaber, Rok (2022) Coupling CRISPR interference with FACS enrichment: New approach in glycoengineering of CHO cell lines for therapeutic glycoprotein production. Biotechnology journal. e2100499. ISSN 1860-7314

Glowienke, Susanne (2022) Principles and Procedures for Assessment of Acute Toxicity Incorporating In Silico Methods. Computational Toxicology.

Glowienke, Susanne (2022) Use of the bacterial reverse mutation assay to predict carcinogenicity of N-nitrosamines. Regulatory toxicology and pharmacology : RTP, 135. p. 105247. ISSN 1096-0295

Glowienke, Susanne, Onken, Ulrich, Muthusamy, sasikumar, Elhajouji, Azeddine, Sangana, Ramachandra, Martus, Hans-Joerg, Bedman, Timothy and Hartmann, Andreas (2022) Genotoxicity evaluation of a valsartan-related complex N-nitroso-impurity. Regulatory toxicology and pharmacology.

Godinez Navarro, William, Ma, Eric, Chao, Alexander, Pei, Amy, Skewes-Cox, Peter, Canham, Steve, Jenkins, Jeremy, Young, Joe, Martin, Eric and Guiguemde, Armand (2022) Design of potent antimalarials with generative chemistry. Nature Machine Intelligence, 4. pp. 180-186. ISSN 2522-5839

Goepfert, Arnaud, Barske, Carmen, Lehmann, Sylvie, Wirth, Emmanuelle, Willemsen, Joschka, Gudjonsson, Johann, Ward, Nicole, Sarkar, Mrinal, Hemmig, Rene, Kolbinger, Frank and Rondeau, Jean-Michel (2022) IL-17-induced dimerization of IL-17RA drives the formation of the IL-17 signalosome to potentiate signaling. Cell reports, 41 (3). p. 111489. ISSN 2211-1247

Gudjonsson, Alexander, Gudmundsdottir, Valborg, Gudmundsson, Elias F, Jonsson, Brynjolfur G, Launer, Lenore J, Lamb, John R, Jennings, Lori, Aspelund, Thor, Emilsson, Valur and Gudnason, Vilmundur (2022) A genome-wide association study of serum proteins reveals shared loci with common diseases. Nature communications.

Guerini, Danilo (2022) STING agonists/antagonists: their potential as therapeutics and future developments. Cells., 11. p. 1159.

Guillon, Antoine, Diakite, Deborah, Cezard, Adeline, Baranek, Thomas, Bourgeais, Jérôme, Picou, Frédéric, Hervé, Virginie, Carballido, Jose, Desbarats, Lydie Nadal, Auvet, Adrien, Dingli, Florent, Turtoi, Andrei, Le Gouellec, Audrey, Fauvelle, Florence, Crépin, Thibaut, Hiemstra, Pieter S, Paget, Christophe, Loew, Damarys, Herault, Olivier, Naffakh, Nadia, Le Goffic, Ronan and Si-Tahar, Mustapha (2022) Host succinate inhibits influenza virus infection through succinylation and nuclear retention of the viral nucleoprotein. The EMBO journal, 41 (12). e108306. ISSN 1460-2075

Gurtan, Allan, Dominy, John, Khalid, Shareef, Vong, Linh, Caplan, Shari, Currie, Treeve, Richards, Sean, Lamarche, Lindsey, Denning, Daniel, Rasheed, Asif, Hameed, Shahid, ul-Asar, Zameer, Saleem, Imran, Jalal, Anjun, Abbas, Shahid, Rasheed, Syed, Memon, Fazal-ur-Rehman, Ishaq, Mohammad, Frossard, Philippe and Saleheen, Danish (2022) Analyzing human knockouts to validate GPR151 as a therapeutic target for reduction of body mass index. PLoS genetics, 18 (4). e1010093. ISSN 1553-7404

H

Haber, Julien, Ausserwöger, Hannes, Lehmann, Claudio, Pillet, Lauriane, Schenkel, Berthold and Guelat, Bertrand (2022) Minimizing Material Consumption in Flow Process Research and Development: A Novel Approach Toward Robust and Controlled Mixing of Reactants. Organic Process Research & Development. ISSN 1083-61601520-586X

Haefliger, Simon, Hench, Juergen, O'Rourke, Colm J, Meyer-Schaller, Nathalie, Uzun, Sarp, Saldarriaga, Joan, Weber, Achim, Mazzucchelli, Luca, Jermann, Philip, Frank, Stephan, Andersen, Jesper B, Terracciano, Luigi, Sempoux, Christine and Matter, Matthias S (2022) Genetic and epigenetic analysis of hepatocellular adenomas with atypical morphological features. Histopathology. ISSN 1365-2559

Hahaut, Vincent, Pavlinic, Dinko, Cowan, Cameron, Schuierer, Sven, Carbone, Walter, Roma, Guglielmo and Picelli, Simone (2022) Lightning Fast and Highly Sensitive Full-Length Single-cell sequencing using FLASH-Seq. Nature biotechnology, 40. ISSN 1087-0156

Hailin, Chen, Tengteng, Yu, Liang, Lin, Lijie, Xing, Shih-Feng, Cho, Kenneth, Wen, Aardalen, Kimberly, Ok, Adwait, Lam, Joni, Daley, Michael, Lu, Haihui, Nikhil, Munshi, Kenneth, Anderson and Yu-Tzu, Tai (2022) γ-secretase inhibitors augment efficacy of BCMA-targeting bispecific antibodies against multiple myeloma cells without impairing T-cell activation and differentiation. Blood cancer journal, 12 (8). p. 118. ISSN 2044-5385

Hamzic, Seid, Lewis, Richard, Desrayaud, Sandrine, Soylu, Cihan, Fortunato, Mike, Gerebtzoff, Gregori and Rodriguez Perez, Raquel (2022) Predicting in vivo brain penetration using multitask graph neural networks. Journal of chemical information and modeling.

Hamzic, Seid, Lewis, Richard, Desrayaud, Sandrine, Soylu, Cihan, Fortunato, Mike, Gerebtzoff, Gregori and Rodriguez Perez, Raquel (2022) Predicting in vivo brain penetration using multitask graph neural networks. Journal of Chemical Information and Modeling. ISSN 1549-95961549-960X

Hamzic, Seid, Lewis, Richard, Desrayaud, Sandrine, Soylu, Cihan, Fortunato, Mike, Gerebtzoff, Gregori and Rodriguez Perez, Raquel (2022) Predicting in vivo brain penetration using multitask graph neural networks. Journal of Chemical Information and Modeling. ISSN 1549-95961549-960X

Hanna, Imad (2022) Clinical Relevance of Hepatic and Renal P-gp/BCRP Inhibition of Drugs: An International Transporter Consortium Perspective. Clinical pharmacology and therapeutics, 112 (3). pp. 573-592. ISSN 1532-6535

Harlacher, Cornelius, Galli, Bruno, Schlauersbach, Jonas, Kehrein, Josef, Hanio, Simon, Heidenreich, Christopher, Lenz, Bettina, Sotriffer, Christoph and Meinel, Lorenz (2022) Predicting Bile and Lipid Interaction for Drug Substances. Molecular pharmaceutics, 19 (8). pp. 2868-2876. ISSN 1543-8392; 1543-8384

Hauptmann, Astrid, Hoelzl, Georg, Mueller, Martin, Bechtold-Peters, Karoline and Loerting, Thomas (2022) Raman marker bands for secondary structure changes of frozen therapeutic monoclonal antibody formulations during thawing. Journal of Pharmaceutical Science, special issue: https://urldefense.com/v3/__https://www.jpharmsci.org/article/S0022-3549(21)00696-1/fulltext__;!!N3hqHg43uw!rGutqxS5yRl_1ftPgG5k7nEB9C2w8AFCJFgp9N1lA9ICdv58OfjHZsQt0AQh2HZbLsq1oyUsOFBHCbBQFO9bBUWa0-8J7EtaC.

Hauseman, Zack, Fodor, Michelle, Viscomi, Jessica, Bleu, Melusine, Galli, Giorgio, Tordella, Luca, Thoma, Claudio and King, Daniel (2022) Cooperative assembly and structure of the RAS-SHOC2-PP1c holophosphatase provides mechanistic insights into disease-relevant mutations. Nature, 609. pp. 416-423. ISSN 1476-4687

Hemsley, Sarah (2022) People of TM: Video of Sarah Hemsley. YouTube.

Henning, Nathaniel, Boike, Lydia, Spradlin, Jessica, Ward, Carl, Zhang, Erika, Belcher, Bridget, Brittain, Scott, Hesse, Matthew, Dovala, Dustin, McGregor, Lynn, Valdez Misiolek, Rachel, Wingert Plasschaert, Lindsey, Rowlands, David, Wang, Feng, fuller, daniel, Estes, Abigail, Frank, Andreas, Randal, Katelyn, Panidapu, Anoohya, McKenna, Jeffrey, Tallarico, John, Schirle, Markus, Nomura, Daniel and Liu, Gang (2022) Deubiquitinase-targeting chimeras for targeted protein stabilization. Nature chemical biology. ISSN 1552-4469

Hernandez Rodriguez, Tanja Nadine, Sekulic, Anton, Lange-Hegermann, Markus and Frahm, Björn (2022) Designing robust biotechnological processes regarding variabilities using multi-objective optimization applied to a biopharmaceutical seed train design. MDPI Processes, 10 (5). p. 883.

Hinterholzer, Arthur, Moises, Jennifer, Regl, Christof, Schwap, Sebastian, Huber, Christian G. and Schubert, Mario (2022) Unambiguous identification of α-Gal epitopes in intact monoclonal antibodies by NMR spectroscopy. mAbs, 14 (1). p. 2132977. ISSN 1942-0870

Hoch, Matthias, Huth, Felix, SATO, MASAHIKO, Sengupta, Tirtha, Quinlan, Michelle, Dodd, Stephanie, Kapoor, Shruti and Hourcade-Potelleret, Florence (2022) Pharmacokinetics of asciminib in the presence of CYP3A or P-gp inhibitors, CYP3A inducers, and acid-reducing agents. Clinical and Translational Science. ISSN 1752-80541752-8062

Hoch, Matthias, Sengupta, Tirtha and Hourcade-Potelleret, Florence (2022) Pharmacokinetic Drug Interactions of Asciminib With the Sensitive Cytochrome P450 Probe Substrates Midazolam, Warfarin and Repaglinide in Healthy Volunteers. Clinical and translational science. ISSN 1752-8062; 1752-8054

Hoppe, Isabel J., Promegger, Bernhard, Uhl, Andreas, Lohrig, Urs, Huber, Christian G. and Brandstetter, Hans (2022) The Fluorescent Enzyme Cascade Detects Low Abundance Protein Modifications Suitable for the Assembly of Functionally Annotated Modificatome Databases. Chembiochem : a European journal of chemical biology, 23 (19). e202200399. ISSN 1439-7633

Horvath, Courtney (2022) People of TM: Video of Courtney Horvath. LinkedIn.

Hoyler, Thomas, Bannert, Bettina, Beck, Damian, Boulay, Thomas, Buffet, David, Caesar, Nadja, Calzascia, Thomas, Dawson King, Janet, Kyburz, Diego, Hennze, Robert, Huppertz, Christine, Littlewood-Evans, Amanda, Loetscher, Pius, Mertz, Kirsten D., Niwa, Satoru, Robert, Gautier, Rush, James, Sarret, Sophie, Stein, Thomas, Touil, Ismahane, Wieczorek, Grazyna, Collignon Zipfel, Geraldine, Hawtin, Stuart and Junt, Tobias (2022) Nonhematopoietic IRAK1 drives arthritis via neutrophil chemoattractants. JCI insight, 7 (13). ISSN 2379-3708

Huang, Ying, Zhang, Jeff, Sendzik, Martin, Gao, Zhenting, Sun, Yongfeng, Wang, Long, Zhang, Lijun, Blanz, Joachim, Dubost, Valerie, Chen, Zijun, Fang, Douglas, Gu, Justin, Kiffe, Michael, Li, Ling, Luo, Fangjun, Luo, Xiao, Mistry, Prakash, Pearson, David, Piaia, Alessandro, Qi, Wei, Scheufler, Clemens, Terranova, Remi, Weiss, Andreas, Yu, Zhengtian, Zeng, Jue, Zhang, Hailong, Zhang, Jiangwei, Zhang, Qiong, Zhao, Kehao, Zhao, Mengxi, Atadja, Peter, Dillon, Michael, Jeay, Sebastien Jeay, Li, En, Moggs, Jonathan, Pissot Soldermann, Carole, Oyang, Counde and Lingel, Andreas (2022) Discovery of the Clinical Candidate MAK683: An EED-Directed, Allosteric, and Selective PRC2 Inhibitor for the Treatment of Advanced Malignancies. Journal of Medicinal Chemistry, 65 (7). pp. 5317-5333. ISSN 0022-26231520-4804

J

Jacob, Sandra, Teng, Mingxing, Luskin, Marlise, Ding, Qiang, Fabbro, Doriano and Gray, Nathanael (2022) The Dawn of Allosteric BCR-ABL1 Drugs: From a Phenotypic Screening Hit to an Approved Drug. Journal of medicinal chemistry, 65 (11). pp. 7581-7594. ISSN 1520-4804

James, Alexander David, Young, Graeme C, Spracklin, Douglas K, Hvenegaard, Mette G, Scarfe, Graeme, Wagner, David S, Georgi, Katrin, Schieferstein, Hanno, Bjornsdottir, Inga, van Groen, Bianca, Cassidy, Kenneth C, Da-violante, Georges, Bister, Bojan, Blech, Stefan, lyer, Ramaswamy, Schulz, Simone, Cuyckens, Filip and Moliner, Patricia (2022) Considerations for Human ADME Strategy and Design Paradigm Shift(s) - An Industry White Paper. Clinical pharmacology and therapeutics. ISSN 1532-6535

Janardhan, Kyathanahalli, Sura, Radhakrishna, Salian-Mehta, Smita, Flandre, Thierry, Palazzi, Xavier, Singh, Bhanu, Hukkanen, Renee Rosemary, Muthafar, Al-Haddawi, Bennet, Bindu, Laast, Victoria, Lee, Donna, Peterson II, Richard, Romeike, Annette, Schorsch, Frédéric and Guffroy, Magali (2022) Opinion on Not Terminating Control Animals in the Recovery Phase of Non-rodent Toxicology Studies. Toxicologic pathology.

Jang, Jun Ho, Wong, Lily, Ko, Bor-Sheng, Yoon, Sung-Soo, Li, Katie, Baltcheva, Irina, Nidamarthy, Prasanna, Chawla, Raghav, Junge, Guido and Yap, Eng Soo (2022) Iptacopan monotherapy in patients with paroxysmal nocturnal hemoglobinuria: a 2-cohort open-label proof-of-concept study. Blood advances. ISSN 2473-9537

Janku, Filip, Han, Sae-Won, Doi, Toshihiko, Amatu, Alessio, Ajani, Jaffer, Kuboki, Yasutoshi, Cortez, Alex, Cellitti, Susan, Chen, Ping, Subramanian, Kulandayan, Schoenfeld, Heidi, Choi, Sarah, Iaconis, Lori, Lee, Lang Ho, Pelletier, Marc, Dranoff, Glenn, Askoxylakis, Vasileios and Siena, Salvatore (2022) Preclinical Characterization and Phase 1 Study of the Anti-HER2-TLR7 Immune Stimulator Antibody Conjugate NJH395 in Patients with HER2-positive Malignancies. Cancer immunology research.

Jansen, Hanneke, Ackloo, Suzanne, Amaro, Rommie, Arrowsmith, Cheryl, Azevedo, Hatylas, Batey, Rob, Bengio, Yoshua, Betz, Ulrich, Bologa, Cristian, Chodera, John, Cornell, Wendy, Dunham, Ian, Ecker, Gerhard, Edfeldt, Kristina, Edwards, Aled, Gilson, Michael, Gordijo, Claudia, Hessler, Gerhard, Hillisch, Alexander, Hogner, Anders, Irwin, John, Kuhn, Daniel, Leach, Andrew, Lee, Alpha, Lessel, Uta, Moult, John, Mugge, Ingo, Oprea, Tudor, Perry, Benjamin, Riley, Patrick, Saikatendu, Kumar, Santhakumar, Vijayaratnam, Schapira, Matthieu, Scholten, Cora, Sharma, Sujata, Todd, Matthew, Vedadi, Masoud and Wilson, Tim (2022) CACHE (Critical Assessment of Computational Hit-finding Experiments): A public-private partnership benchmarking initiative to enable the development of computational methods for hit-finding. Nature reviews. Chemistry, 6 (4). pp. 287-295. ISSN 2397-3358

Jansen, Hanneke, Smith, Thomas, Woods, Angela, Parker, David, Glick, Meir, Peng, Y, Lenoir, Francois, Mulligan, Evan, Yu, Vincent, Rakiec, C, Piizzi, Grazia, Lister, Troy, Ryder, Neil and Dean, Charles (2022) High-Throughput Screen for Inhibitors of Klebsiella pneumoniae Virulence Using a Tetrahymena pyriformis Co-Culture Surrogate Host Model. ACS omega, 7 (6). pp. 5401-5414. ISSN 2470-1343

Jelsch, Morgane, Roggo, Yves, mohamad, ahmad, Kleinebudde, Peter and Krumme, Markus (2022) Automatic system dynamics characterization of a pharmaceutical continuous production line. Journal of Pharmaceutical and Biomedical Analysis.

Jennings, Lori (2022) SomaScan Proteomics Profiling - An Overview for (potential) External Collaborators. general distribution.

Ji, Yan, Chen, Heller, Knee, Deborah, Dang, Anhthu, Mataraza, Jennifer, Wolf, Babette and Sy, Sherwin (2022) Model-informed drug development for immuno-oncology agonistic anti-GITR antibody GWN323: MABEL-based dose selection, translational and clinical PK/PD modeling. Clinical and translational science.

Ji, Yan, Knee, Deborah, Chen, Heller, Dang, Anhthu, Mataraza, Jennifer, Wolf, Babette and Sy, Sherwin (2022) Model-informed drug development for immuno-oncology agonistic anti-GITR antibody GWN323: Dose selection based on MABEL and biologically active dose. Clinical and translational science, 15 (9). pp. 2218-2229. ISSN 1752-8062

Ji, Yan, Huang, Pai-Hsi, Woolfenden, Stephen and Myers, Andrea (2022) Model-based dose selection to inform translational clinical oncology development of WNT974, a first-in-class Porcupine inhibitor. Clinical and translational science. ISSN 1752-8062

Ji, Yan, Huang, Pai-Hsi, Woolfenden, Stephen and Myers, Andrea (2022) Model-based dose selection to inform translational clinical oncology development of WNT974, a first-in-class Porcupine inhibitor. Clinical and translational science. pp. 1-10. ISSN 1752-8062

Jones, Graham, Freeman, Jason, Mann, Allison and Khanna, Amit (2022) Physician Centricity in the Deployment of Digital Solutions for Neurological Conditions. DIGITAL HEALTH, 8 (1-2). pp. 1-2. ISSN 2055-20762055-2076

Junge, Guido, Mehes, Beata, Meiser, Karin, Gatlik, Ewa, Sommer, Ulrike, Madurka, Ildiko, Rezende, Ederlon, Vishnevsky, Alexander, Soriano, Joan B, Gans, Stephanus J., Salazar Ore, Danilo Joel, Rendon, Adrian, Suppli Ulrik, Charlotte, Bhatnagar, Sushma, Krishnamurthy, Srikanth, Mc Harry, Kirsten, Welte, Tobias and Fernandez, Alberto Alfredo (2022) Publication of results from DFV890D12201 study: DFV890, a new oral NLRP3 inhibitor, tested for the treatment of SARS-CoV-2 infected patients with COVID-19 pneumonia and impaired respiratory function: Results from a randomised Phase 2 trial. DFV890, a new oral NLRP3 inhibitor, tested for the treatment of SARS-CoV-2 infected patients with COVID-19 pneumonia and impaired respiratory function: Results from a randomised Phase 2 trial. ISSN 1439-0973 (electronic), 0300-8126 (print)

K

Kapun, Aleks, Hrovat, Grega, Gradišek, Jure, Hriberšek, Matjaž, Ravnik, Jure, Bombek, Gorazd, Hribernik, Aleš, Gomboc, Timi and Zadravec, Matej (2022) Energy Intake Models for Intermittent Operation of Dead-End Microfiltration Filling Line. Energies, 15 (23). ISSN 1996-1073

Kapur, Karen, Freidank, Moritz and Rebhan, Michael (2022) Understanding the chronic kidney disease landscape using patient representation learning from electronic health records. medRxiv.

Kastrinou Lampou, Vlasia, Poller, Birk, Huth, Felix, Schadt, Heiko, Fischer, Audrey, Kullak-Ublick, Gerd-Achim, Camenisch, Gian P. and Michael, Arand (2022) Novel insights into bile acid detoxification via CYP, UGT and SULT enzymes. Toxicology in vitro.

Khan, Munzareen, Hartmann, Anna H, O'Donnell, Michael P, Piccione, Madeline, Pandey, Anjali, Chao, Pin-Hao, Dwyer, Noelle D, Bargmann, Cornelia I and Sengupta, Piali (2022) Context-dependent reversal of odorant preference is driven by inversion of the response in a single sensory neuron type. PLoS biology, 20 (6). e3001677. ISSN 1545-7885

Kimball, Alexa B, Loesche, Christian, Prens, Errol P, Bechara, Falk G, Weisman, Jamie, Rozenberg, Izabela, Jarvis, Philip, Peters, Thomas, Roth, Lukas, Wieczorek, Grazyna, Kolbinger, Frank and Jemec, Gregor BE (2022) IL-17A is a pertinent therapeutic target for moderate-to-severe hidradenitis suppurativa: Combined results from a pre-clinical and phase II proof-of-concept study. Experimental dermatology, 31 (10). pp. 1522-1532. ISSN 1600-0625

Koh, Esther, Freedman, Benjamin R, Ramazani, Farshad, Gross, Johannes, Graham, Adam, Kuttler, Andreas, Weber, Eckhard and Mooney, David J (2022) Controlled Delivery of Corticosteroids Using Tunable Tough Adhesives. Advanced healthcare materials. e2201000. ISSN 2192-2659

Kotla, Niranjan, Pandey, Abhijeet, Yadaki, Vijaya Kumar, Langlois, Jean-Baptiste, Fisch, Andreas and Ramazani, Farshad (2022) Polyester-based long acting injectables: Advancements in molecular dynamics simulation and technological insights. Drug discovery today. p. 103463. ISSN 1878-5832

Kranjc, Matej, Dermol-Cerne, Janja, Potočnik, Tjaša, Novickij, Vitalij and Miklavčič, Damijan (2022) High-Intensity Pulsed Electromagnetic Field-Mediated Gene Electrotransfection In Vitro. International Journal of Molecular Sciences, 23 (17). p. 9543. ISSN 1422-0067

Kroemer, Markus and Ostermeier, Daniela (2022) Tackling Challenging Targets with High-Throughput Biophysical Screening at Novartis. Scaling Up Surface Plasmon Resonance-Based Screens to Increase Novel Hit Finding.

L

Lanshoeft, Christian, Lozac'h, Frederic and Higton, David (2022) Use of predicted versus measured CCS values from different instrument platforms, and isomer separation on the SELECT SERIES Cyclic IMS. Waters Application Note.

Lara, Zentsche, Jessica, Yazarians, Suman, Chakrabarty, Meagan, Hinze, April, Lukowski, Leo, Joyce and Alison, Narayan (2022) Biaryl bond formation through biocatalytic oxidative cross-coupling reactions. Nature, 603. pp. 79-85. ISSN https://doi.org/10.1038/s41586-021-04365-7

Lee, Judy (2022) Formulated oligonucleotide APIs: Regulatory aspects. Therapeutic innovation & regulatory science, 2022 (56). pp. 386-393. ISSN 2168-4790; 2168-4804

Lehermayr, Christian, Podobnik, Barbara and Graf, Christian (2022) Open channel for external industry technology providers to centrally upload technology offers to a Novartis web portal. https://digitalbrain.novartis.com/, n.a. (n.a.). n.a.-n.a.. ISSN n.a.

Lehmann, Hansjoerg, Knoepfel, Thomas and Ruppen, Thomas (2022) Scale-up of Diazonium Salts and Azides in a Three-step Continuous Flow Sequence. Organic Process Research & Development.

Lemmens, Myriam, Zogg, Michael, Potgeter, Leon, Perner, Juliane, Thiruchelvam, Sineha, Mueller, Matthias, Werner, Annick, Doll, Thierry, Gilbart, Yoann, Couttet, Philippe and Libertini, Silvana (2022) Identification and validation of marker genes for the detection of residual iPSCs in iPSC-derived Cardiomyocytes. Cytotherapy : official journal of the International Society for Hematotherapy and Graft Engineering..

Lenz, Jan, Fuest, Frederik, Finek, Jan Hendrik, Bunjes, Heike, Kwade, Arno and Juhnke, Michael (2022) Tablet disintegration and dispersion under in vivo-like hydrodynamic conditions. Pharmaceutics, 14 (n.a.). pp. 1-25. ISSN 1999-4923

Li, Wenkui and Picard, Franck (2022) Toxicokinetics in preclinical drug development of small-molecule new chemical entities. Biomedical Chromatography. n/a-n/a. ISSN 0269-3879

Li, Ying Fei, Combes, Francois Pierre, Hoch, Matthias, Lorenzo, Sebastien, Sy, Sherwin and Ho, Yu-Yun (2022) Population pharmacokinetics of asciminib in tyrosine kinase inhibitor-treated patients with Philadelphia chromosome-positive chronic myeloid leukemia in chronic and acute phases. Clinical Pharmacokinetics, 61 (5). ISSN 0312-5963

Libertini, Silvana (2022) People of TM: Video of Slivana Libertini. YouTube.

Linker, Stephanie, Schellhaas, Christian , Ries, Benjamin , Roth, Hans-Joerg, Fouche, Marianne, Rodde, Stephane and Riniker, Sereina (2022) Polar/Apolar Interfaces Modulate the Conformational Behavior of Cyclic Peptides with Impact on Their Passive Membrane Permeability. RSC advances, 12 (10). pp. 5782-5796.

Lopez, John, Ackermann, Damian and Heilmann, Tobias (2022) Refractive Index to Monitor Solid-Phase Oligonucleotide Synthesis. Organic Process Research & Development. ISSN 1083-61601520-586X

Lopez, John, Bucher, Christoph, Beck, Janina, Berthelmann, Arne, Spyridon, Markos and Eisser, Stefan (2022) THE MISSING LINK: ENABLING LOADING OF 2-CHLOROTRITYL CHLORIDE RESIN IN N-BUTYLPYRROLIDINONE AS A GREEN SOLVENT. Organic Process Research & Development, 26 (5). pp. 1450-1457. ISSN 1083-61601520-586X

Lorthiois, Edwige, Gerspacher, Marc, Beyer, Kim, Vaupel, Andrea, Leblanc, Catherine, Stringer, Rowan, Weiss, Andreas, Wilcken, Rainer, Guthy, Daniel Alexander, Lingel, Andreas, Bomio-Confaglia, Claudio, Machauer, Rainer, Rigollier, Pascal, Ottl, Johannes, Arz, Dorothee, Bernet, Pascal, Desjonqueres, Gaelle, Dussauge, Solene, Kazic-Legueux, Malika, Lozac'h, Marie-Anne, Mura, Christophe, Sorge, Mickael, Todorov, Milen, Warin, Nicolas, Zink, Florence, Voshol, Johannes, Zecri, Frederic, Sedrani, Richard, Ostermann, Nils and Brachmann, Saskia (2022) JDQ443, a Structurally Novel, Pyrazole-Based, Covalent Inhibitor of KRASG12C for the Treatment of Solid Tumors. Journal of medicinal chemistry, 65 (24). pp. 16173-16203. ISSN 1520-4804

Loryan, Irena, Reichel, Andreas, Feng, Bo, Bundgaard, Christopher, Shaffer, Christopher, Kalvass, Cory, Bednarczyk, Dallas, Morrison, Denise, Lesuisse, Dominique, Hopper, Edmund, Terstappen, Georg, Fischer, Holger, Di, Li, Colclough, Nicola, Summerfield, Scott, Buckley, Stephen, Maurer, Tristan and Friden, Markus (2022) Unbound Brain-to-Plasma Partition Coefficient, Kp,uu,brain-a Game Changing Parameter for CNS Drug Discovery and Development. Pharmaceutical research. ISSN 1573-904X

Lüönd, Fabiana, Pirkl, Martin, Hisano, Mizue, Prestigiacomo, Vincenzo, Kalathur, Ravi Kr, Beerenwinkel, Niko and Christofori, Gerhard (2022) Hierarchy of TGFβ/SMAD, Hippo/YAP/TAZ, and Wnt/β-catenin signaling in melanoma phenotype switching. Life science alliance, 5 (2). ISSN 2575-1077

M

Madl, Amy, Liu, Chunzi, Cirera-Salinas, Daniel, Myung, David and Fuller, Gerald (2022) A Mucin-Deficient Ocular Surface Mimetic Platform for Interrogating Drug Effects on Biolubrication, Anti-Adhesion Properties, and Barrier Functionality. ACS Applied Materials & Interfaces, 14 (16). pp. 18016-18030. ISSN 1944-82441944-8252

Madren, Seth, McElroy, Will, Schultz-Kuszak, Kristin, Boumajny, Boris, Shu, Yao, Sautter, Sabine, Zhao, Helen C, Schadock-Hewitt, Abby, Chumsae, Chris, Ball, Nancy, Xiaoying, Zhang, Rish, Kimberly , Shukui, Zhang , Wurm, Christine , Cai, Sumin , Bauer, Scott P , Stella, Cinzia , Zheng, Laura, Roper, Brian , Michels, David A , Wu, Gang , Kocjan, Bostjan, Birk, Matej, Erdmann, Simon Erik, He, Xiaoping, Whittaker, Brad, Song, Yvonne, Barrett, Hannah, Strozyk, Kevin, Jing, Ye, Huang, Long, Mhatre, Vishal, McLean, Paul, Yu, Tiantian, Yang, Huijuan and Mattila, Minna (2022) Global intercompany assessment of ICIEF platform comparability for the characterization of therapeutic proteins. Electrophoresis.

Manjunatha, Ujjini, Lakshminarayana, Suresh, Jumani, Rajiv Satish, Chao, Alexander, Young, Joe, Gable, Jonathan, Knapp, Mark, Hanna, Imad, Galarneau, Jean-Rene, Cantwell, John, Kulkarni, Upendra, Turner, Michael, Chan, Katherine, Patra, Debjani, Mamo, Mulugeta, Luu, Catherine, Xiao, Linda, Chen, Ying-Bo, Shannon, Carney, Lakshman, Jay, Osborne, Colin, Zaror, Isabel, Jennifer, Zambriski, Gu, Feng, Sarko, Christopher and Diagana, Thierry (2022) Cryptosporidium PI(4)K inhibitor EDI048 is a gut-restricted parasiticidal agent to treat paediatric enteric cryptosporidiosis. Nature microbiology.. ISSN 2058-5276

Mann, Greg, Stanger, Frederic, Peschke, Theo, Schroer, Kirsten, Nguyen Trung, Nhat Quang, Burrer, Nathalie, Grassinger, Franziska, Piccioni, Lorenzo, Erdogan, Oemer, Heimburger, Jeremy, Koehl, Herve, Ertle, Heike, Denay, Regis, Dreier, Philippe and Schlama, Thierry (2022) Biocatalytic assembly of chemically modified oligonucleotides. Tetrahedron letters. ISSN 00404039

Martin, Eric, Born, Jannis, Shoshan, Yoel, Huynh, Tien, Cornell, Wendy D. and Manica, Matteo (2022) On the Choice of Active Site Sequences for Kinase-Ligand Affinity Prediction. Journal of chemical information and modeling, 62 (18). pp. 4295-4299. ISSN 1549-960X

Mastropietro, Andrea, Pasculli, Giuseppe, Feldmann, Christian, Rodriguez Perez, Raquel and Bajorath, Juergen (2022) EdgeSHAPer: Bond-Centric Shapley Value-Based Explanation Method for Graph Neural Networks. iScience. ISSN 25890042

McCauley, Katie, Kukreja, Kalki, Jaffe, Aron and Klein, Allon (2022) A map of signaling responses in the human airway epithelium. bioRxiv : the preprint server for biology.

McConn, Betty R., Schinckel, Allan P., Robbins, Lindsey, Gaskill, Brianna N., Green-Miller, Angela R., Lay, Donald C. and Johnson, Jay S. (2022) A behavior and physiology-based decision support tool to predict thermal comfort and stress in non-pregnant, mid-gestation, and late-gestation sows. Journal of Animal Science and Biotechnology, 13 (1). ISSN 2049-1891

McKenna, Jeffrey, Saini, Vaneet, Chaudhary, Nishita, Singh, Kamal Nain and Singh, Harjinder (2022) Transition-Metal Free Allylic Fluorination of Acyclic Olefins. Synthesis. ISSN 1437-210X; 0039-7881

McKenna, Jeffrey, Schirle, Markus, Tallarico, John, Brittain, Scott, Scholz, Spencer, Near, Katherine, Page, Annika, Spradlin, Jessica, Nomura, Daniel and Toste, F Dean (2022) Photo-Brook rearrangement of acyl silanes as a new tool for photoaffinity probes design. Chem Sci.

Medina-Franco, Jose Luis, Gasteiger, Johann, Bajorath, Juergen, Mendez Lucio, Oscar and Rodriguez Perez, Raquel (2022) Chemoinformatics and Artificial Intelligence Colloquium: Progress and Challenges to Develop Bioactive Compounds. Journal of cheminformatics.

Menichelli, Elena, Lam, Bianca J., Wang, Yu, Wang, Vivian S., Shaffer, Jennifer, Tjhung, Katrina F., Bursulaya, Badry, Nguyen, Truc, Vo, Michael, Alper, Phillip, McAllister, Christopher, Jones, David, Spraggon, Glen, Michellys, Pierre-Yves, Joslin, John, Joyce, Gerald F. and Rogers, Jeff (2022) Discovery of Small Molecules that Target a Tertiary-Structured RNA. Proceedings of the National Academy of Sciences of the United States of America PNAS., 119 (48). ISSN 0027-8424

Menichelli, Elena, Lam, Bianca J., Wang, Yu, Wang, Vivian S., Shaffer, Jennifer, Tjhung, Katrina F., Bursulaya, Badry, Vo, Michael, Alper, Phillip, McAllister, Christopher, Jones, David, Spraggon, Glen, Michellys, Pierre-Yves, Joslin, John, Joyce, Gerald F. and Rogers, Jeff (2022) Discovery of small molecules that target a tertiary-structured RNA. Proceedings of the National Academy of Sciences of the United States of America, 119 (48). e2213117119. ISSN 1091-6490

Meseck, Emily, Mansfield, Keith, Hudry, Eloise, McElroy, Cameron and Guibinga, Ghiabe (2022) Intrathecal sc-AAV9-CB-GFP: Systemic Distribution Predominates Following Single-Dose Administration in Cynomolgus Macaques. Toxicologic pathology.

Meyer, Robina Mareike, Aleshkevich, Sofya, Berger, Lukas, Nerkamp, Joerg, Scheler, Stefan and Friess, Wolfgang (2022) Characterization of the aggregation propensity of charge variants of recombinant human growth hormone. International journal of pharmaceutics, 621. p. 121760. ISSN 1873-3476

Michel, Erich, Cucuzza, Stefano, Mittl, Peer R E, Zerbe, Oliver and Plückthun, Andreas (2022) Improved Repeat Protein Stability by Combined Consensus and Computational Protein Design. Biochemistry. ISSN 1520-4995

Mikhailov, Dmitri, Li, Wenkui and Leuthold, Luc Alexis (2022) Leveraging patient-centric sampling for clinical drug development and decentralized clinical trials: promise to reality. Clinical Translational Sciences.

Milton, Mark, Dodge, Robert and Potthoff, Bernd (2022) 2021 White Paper on Recent Issues in Bioanalysis: TAb/NAb, Viral Vector CDx, Shedding Assays; CRISPR/Cas9 & CAR-T Immunogenicity; PCR & Vaccine Assay Performance; ADA Assay Comparability & Cut Point Appropriateness. Bioanalysis.

Mitchell, Gabriel, Roma, Guglielmo, Voorberg-van der Wel, Annemarie, Beibel, Martin, Zeeman, Anne-Marie, Schuierer, Sven, Torres, Laura, Flannery, Erika, Kocken, Clemens, Mikolajczak, Sebastian and Diagana, Thierry (2022) Transcriptional profiling of hepatocytes infected with the replicative form of the malaria parasite Plasmodium cynomolgi. Malaria journal, 21 (1). p. 393. ISSN 1475-2875

Moebitz, Henrik, Gruenenfelder, Bjoern, Kiffe, Michael, Ramos, Rita, Ramulu, Poddutoori, Kiran, Aithal, Mark, Bock, Sanjeev, BS, Shekar, Chelur, T S, Devaraja, Sreevalsam, Gopinath, Andrea, Gerken, Charamanna , KB, Maithreyi, Krishnaswami, John, Langowski, Sudarshan, Madapa, Kishore, Narayanan, Ravi Kumar , P, Chetan, Pandit, Sunil Kumar, Panigrahi, Mark, Perrone, Murali, Ramachandra, Anuradha, Ramanathan, Susanta, Samajdar, Hosahalli, Subramanya and Eleni, Venetsanakos (2022) Discovery of MAP855, an efficacious and selective MEK1/2 inhibitor with ATP-competitive mode of action. Journal of Medicinal Chemistry.

Moises, Jennifer E, Regl, Christof, Hinterholzer, Arthur, Huber, Christian and Schubert, Mario (2022) Unambiguous Identification of Glucose-Induced Glycation in mAbs and other Proteins by NMR Spectroscopy. Pharmaceutical research. ISSN 1573-904X

Molony, Ryan, Funk, Theresa, Trabucco, Gina, Corcoran, Erik, Ruddy, David, Varadarajan, Malini, Elliott, GiNell, Piquet, Michelle, Lam, Joni, Matthew, Meyer, Wang, Hui-Qin, Kurtulus-Aksoylar, Sema and Lu, Haihui (2022) CRISPR screening identifies T cell-intrinsic regulators of CD3-bispecific antibody responses. Frontiers in immunology, 13. p. 909979. ISSN 1664-3224

Moraitis, Alexandra (2022) The function of 14-3-3 protein family and its connection with cancer review. University business..

Mueller-Zsigmondy, Martin, Mann, James, Hermans, Andre, Contrella, Nathan, Nickerson, Beverly, Coutant, Carrie A., Jede, Christian, Kao, Shangming, Kou, Dawen, Scheubel, Emmanuel, Winge, Fredrik, Milsmann, Johanna and Zaborenko, Nikolay (2022) Dissolution Method Troubleshooting: An Industry Perspective. Dissolution technologies, 29 (4). pp. 190-203. ISSN 1521298X

N

Naranjo, Chris, Dalvie, Neil C., Rodriguez-Aponte, Sergio A., Johnston, Ryan S. and Christopher Love, J. (2022) Steric accessibility of the N-terminus improves the titer and quality of recombinant proteins secreted from Komagataella phaffii. Microbial Cell Factories, 21 (1). ISSN 1475-2859

Nichimura, Jun-Ichi, Ando, Kiyoshi, Masuko, Masayoshi, Noji, Hideyoshi, Ito, Yoshikazu, Mayer, Jiri, Griskevicius, Laimonas, Bucher, Christoph, Muellershausen, Florian, Gergely, Peter, Rozenberg, Izabela, Schubart Wellensiek, Anna, Chawla, Raghav, Rondeau, Jean-Michel, Roguska, Michael, Splawski, Igor, Keating, Mark, Johnson, Leslie, Danekula, Rambabu, Bagger, Morten, WATANABE, YOKO, Haraldsson, Boerje and Kanakura, Yuzuru (2022) Tesidolumab (LFG316) for treatment of C5-variant patients with paroxysmal nocturnal hemoglobinuria. Haematologica, 107 (6). pp. 1483-1488.

Nienhold, Ronny, Mensah, Nadine, Frank, Angela, Graber, Anne, Koke, Jacqueline, Scjwab, Nathalie, hernach, Claudia, Zskila, Veronika, Willi, Niels, Cathomas, Gieri, Graf, Susanne, Junt, Tobias and Mertz, Kirsten D. (2022) Unbiased screen for pathogens in human paraffin-embedded tissue samples by whole genome sequencing and metagenomics. Frontiers in cellular and infection microbiology, 12. p. 968135. ISSN 2235-2988

Nilsson, Inga and Six, David A. (2022) Metabolic Incorporation of Azido-Sugars into LPS to Enable Live-Cell Fluorescence Imaging. Lipopolysaccharide Transport, 2548. pp. 267-278. ISSN 1064-3745

O

O'Donnell, Chris and Bradner, Jay (2022) Bridging the Gap to Translating Genomewide Discoveries into Therapies to Prevent and Treat Atherosclerotic Cardiovascular Disease. Circulation, 146 (12). pp. 930-933. ISSN 0009-7322

P

Parmentier, Michael, Hoehn, Pascale, Marti, Roger, Dabros, Michal, Brodard, Pierre, Ferrari, Thomas, Blum, Caitlin and Amini-Rentsch, Lara (2022) Development, Validation, and Application of a Custom-Made Mini-Reaction Calorimeter for Thermal Safety Screening. Organic Process Research & Development. ISSN 1083-61601520-586X

Parmentier, Michael, Li, Wei and Steven, Alan (2022) Green Chemistry Articles of Interest to the Pharmaceutical Industry. Organic Process Research & Development.

Parmentier, Michael, Udvarhelyi, Aniko, Hoehn, Pascale, Amini-Rentsch, Lara, Blum, Caitlin, Ferrari, Thomas, Brodard, Pierre, Dabros, Michal and Marti, Roger (2022) Thermal Safety and Structure-Related Reactivity Investigation of Five-Membered Cyclic Sulfamidates. Organic Process Research & Development. ISSN 1083-61601520-586X

Parmentier, Michael, Li, Wei and Steven, Alan (2022) Green Chemistry Articles of Interest to the Pharmaceutical Industry. Organic Process Research & Development. ISSN 1083-61601520-586X

Pearson, David, Jin, Yi, Romeo, Andrea, Birlinger, Bertrand-Luc, Schiller, Hilmar, Ji, Yan, Gunduz, Mithat, Baldoni, Daniela and Walles, Markus (2022) Species-dependent hepatic and intestinal metabolism of selective oestrogen receptor degrader LSZ102 by sulphation and glucuronidation. Xenobiotica. pp. 1-12. ISSN 0049-82541366-5928

Pearson, David, Jin, Yi, Romeo, Andrea, Birlinger, Bertrand-Luc, Schiller, Hilmar, Ji, Yan, Gunduz, Mithat, Baldoni, Daniela and Walles, Markus (2022) Species-dependent hepatic and intestinal metabolism of selective oestrogen receptor degrader LSZ102 by sulphation and glucuronidation. Xenobiotica; the fate of foreign compounds in biological systems. pp. 1-12. ISSN 1366-5928

Petricoul, Olivier, Nazarian, Arman, Schuehly, Uwe, Schramm-Franz, Ursula, David, Olivier, Laurent, Didier, Praestgaard, Jens, Roubenoff, Ronenn, Papanicolaou, Dimitris and Rooks, Daniel (2022) Pharmacokinetics and Pharmacodynamics of Bimagrumab (BYM338). Clinical pharmacokinetics, 62 (1). pp. 141-155. ISSN 1179-1926

Pivk-Lukancic, Petra, Drčar, Tjaša, Bruccoleri, Robert, Crnugelj, Martin and Mrak, Peter (2022) Teleocidin-producing genotype of Streptomyces clavuligerus ATCC 27064. Applied microbiology and biotechnology. ISSN 1432-0614

Pognan, Francois, Timsit, Yoav, Wolf, Armin, Couttet, Philippe, Buono, Chiara and Galarneau, Jean-Rene (2022) Liver enzyme delayed clearance in rat treated by CSF1 receptor specific antagonist Sotuletinib. Current Research in Toxicology, 3.

Poller, Birk, Wartmann, Markus and Huth, Felix (2022) Time matters – in vitro cellular disposition kinetics help rationalizing cellular potency disconnects. Xenibiotica, 52 (8). pp. 878-889.

Poller, Birk, Werner, Sophie, Domange, Norbert, Bednarczyk, Dallas, Mettler, Lina, Stein, Richard, Loretan, Jacqueline, Wartmann, Markus, Faller, Bernard and Huth, Felix (2022) Time matters – In vitro cellular disposition kinetics help identifying disconnects in cell-based potency assays. Xenobiotica, 52 (8). pp. 878-889. ISSN https://doi.org/10.1080/00498254.2022.2130837

Poor, Stephen, Weissgerber, Georges, Adams, Christopher, Watters, Christie, Ferriere, Michael, Chastain, Jim, Gedif, Kinfemichael, Harit, Bhatt, David , Browning, Thomas, Ciulla, Louis , Glazer, Brian, Joondeph, Veeral , Sheeth and Grosskreutz, Cyndy (2022) A Randomized, Double-Masked, Multicenter Trial of Topical Acrizanib (LHA510), a Tyrosine Kinase VEGF-Receptor Inhibitor, in Treatment-Experienced Subjects With Neovascular Age-Related Macular Degeneration. American journal of ophthalmology, 239. pp. 180-189. ISSN 1879-1891

Prabhath, Anupama , Vernekar , Varadraj N, Esdaille, Caldon J, Eisenberg , Ellen , Lebaschi , Amir, Badon , Mary , Seyedsalehi, Amir, Dzidotor , Godwin , Tang, Xiaoyan , Dyment , Nathaniel , Thomopoulos , Stavros , Kumbar , Sangamesh G, Deymier, Alix, Weber, Eckhard and Laurencin , Cato T (2022) Pegylated insulin-like growth factor-1 biotherapeutic delivery promotes rotator cuff regeneration in a rat model. Journal of biomedical materials research. Part A. ISSN 1552-4965

Pretre, Vincent, Papadopoulos, Dimitrios, Regard, Jean, Pelletier, Marc and Woo, Janghee (2022) Interleukin-1 (IL-1) and the inflammasome in cancer. Cytokine, 153. ISSN 1043-4666

Pritchett, RK, Gaskill, BN, Erasmus, MA, Radcliffe, JS and Lay, DC (2022) Scratch that itch: Farrowing crate scratching enrichment for sows. Animal Welfare, 31 (2). pp. 243-255. ISSN 0962-7286

Q

Quackenbush, Doug, Chu, Tiffany, Lo, Frederick, Sutherland, Jeffrey, Kuzu, Guray, Roberts, Chris, Luna, Fabio, Barnes, Whitney, Walker, John and Kuss, Pia (2022) "3D, human renal proximal tubule (RPTEC-TERT1) organoids 'tubuloids' for translatable evaluation of nephrotoxins in high-throughput". PloS one, 17 (11). e0277937. ISSN 1932-6203

Quintavalle, Cristina, Meyer-Schaller, Nathalie, Roessler, Stephanie, Calabrese, Diego, Marone, Romina, Riedl, Tobias, Picco-Rey, Silvia, Panagiotou, Orestis A, Uzun, Sarp, Piscuoglio, Salvatore, Boldanova, Tuyana, Bian, Chaoran B, Semela, David, Jochum, Wolfram, Cathomas, Gieri, Mertz, Kirsten D, Diebold, Joachim, Mazzucchelli, Luca, Koelzer, Viktor H, Weber, Achim, Decaens, Thomas, Terracciano, Luigi M, Heikenwalder, Mathias, Hoshida, Yujin, Andersen, Jesper B, Thorgeirsson, Snorri S and Matter, Matthias S (2022) miR-579-3p Controls Hepatocellular Carcinoma Formation by Regulating the Phosphoinositide 3-Kinase-Protein Kinase B Pathway in Chronically Inflamed Liver. Hepatology communications. ISSN 2471-254X

R

Rao, V. Koneti, Webster, Sharon, Sediva, Anna, Plebani, Alessandro, Schuetz, Catharina, Shcherbina, Anna, Conlon, Niall, Coulter, Tanya, Dalm, Virgil A., Trizzino, Antonino, Zharankova, Yulia, Kulm, Elaine, Körholz, Julia, Lougaris, Vassilios, Rodina, Yulia, Radford, Kathryn, Bradt, Jason, Kucher, Klaus, Relan, Anurag, Holland, Steven, Lenardo, Michael J. and Uzel, Gulbu (2022) Randomized, Placebo-Controlled, Phase 3 Trial of PI3Kδ Inhibitor Leniolisib for Activated PI3Kδ Syndrome. Blood. ISSN 1528-0020

Rawat, Manoj, Natasha , Manners, Vishnu, Priya , Abhishesh Kumar , Mehata and Madaswamy S, Muthu (2022) Theranostic Nanomedicines for the Treatment of Cardiovascular and Related Diseases: Current Strategies and Future Perspectives. Pharmaceuticals, 15 (4). p. 441. ISSN 1424-8247

Reddy, K. Raja , Totrov, Maxim , Lomovskaya, Olga, Griffith, David C. , Tarazi, Ziad , Clifton, Matt and Hecker, Scott J. (2022) Broad-spectrum cyclic boronate β-lactamase inhibitors featuring an intramolecular prodrug for oral bioavailability. Bioorganic & medicinal chemistry, 62. p. 116722. ISSN 1464-3391

Rees, David C, Kilinc, Yurdanur, Unal , Selma, Dampier, Carlton, Pace, Betty S, Kaya, Banu, Trompeter, Sara, Odame , Isaac, Mahlangu, Johnny, Unal, Sule, Brent, Julie, Grosse, Regine, Fuh, Beng R, Inusa, Baba PD, Koren, Ariel, Levin, Carina, McNamara, Elizabeth, Meiser, Karin, Hom, Douglas and Oliver, Stephen (2022) Inhibiting IL-1beta-mediated inflammation in pediatric and young adult patients with sickle cell anemia: a randomized, placebo-controlled, double-blind trial with canakinumab (ACZ885). Blood.

Reeves, Audrey, Christian, Alec, McKenna, Jeffrey, Lewis, Richard, Fang, Eric, Dovala, Dustin, McGregor, Lynn, Schirle, Markus, Tallarico, John, Nomura, Daniel, Toste, Dean and Chang, Christopher (2022) An Activity-Based Oxaziridine Platform for Developing Covalent Ligands Against Functional Allosteric Methionine Sites: Redox-Dependent Inhibition of Cyclin-Dependent Kinase 4. JACS.

Reilly, Dorothy, Alharbi, Ebtisam, Gadiya, Yojana , Henderson, David, Zaliani, Andrea , Delfin-Rossaro, Alejandra , Cambon-Thomsen, Anne , Witt, Gesa , Welter, Danielle , Juty, Nick, Jay, Caroline, Goble, Carol, Satagopam, Venkata , Ioannidis, Vassilios , Gu, Wei and Gribbon, Phil (2022) Selection of datasets for FAIRification in Drug Discovery and Development: Which, Why, and How? Drug discovery today. ISSN 1878-5832

Rodriguez Perez, Raquel, Trunzer, Markus, Schneider, Nadine, Faller, Bernard and Gerebtzoff, Gregori (2022) Multi-species machine learning predictions of in vitro intrinsic clearance with uncertainty quantification analyses. Molecular Pharmaceutics. ISSN 1543-83841543-8392

Rodriguez Perez, Raquel, Miljkovic, Filip and Bajorath, Jürgen (2022) Machine Learning in Chemoinformatics and Medicinal Chemistry. Annual review of biomedical data science. ISSN 2574-3414

Roediger, Ben and Schlapbach, Christoph (2022) T cells in the skin: lymphoma and inflammatory skin disease. The journal of allergy and clinical immunology, 149. pp. 1172-1184. ISSN 1097-6825

Roggo, Yves, Martinez Heredia, Lizbeth, Peinado Amores, Antonio and Matero, Sanni (2022) Near infrared spectroscopy for blend uniformity monitoring: an innovative qualitative application based on the coefficient of determination. Journal of near infrared spectroscopy, 30 (6). pp. 322-336. ISSN 1364-6575; 0967-0335

Ruddy, David, Cremasco, Viviana, Chang, Jonathan, Piquet, Michelle and Ittershagen, Stacie (2022) Harnessing Drivers of Pancreatic Cancer Plasticity for Therapeutic Intent. Figures to be submitted as part of a P01 grant.

S

Salazar, Mario G, Cervera, Iris P, French, Karen, Garcia-Martin, Ruben, Bluher, Matthias, Schofield, Chris, Chavakis, Trian, Gudmundsson, Elias F, Radcliffe, Peter, Jennings, Lori, Gudnason, Vilmundur, Morton, Nicholas M, Emilsson, Valur and Machailidou, Zoi (2022) Adipocyte-specific deletion of the oxygen-sensor PHD2 sustains elevated energy expenditure at thermoneutrality. https://www.biorxiv.org/content/10.1101/2021.01.05.425401v1.full.

Saldivia Concepcion, Manuel Alejandro (2022) CLK1/CLK2-driven signalling at the Leishmania kinetochore is captured by spatially referenced proximity phosphoproteomics. Communications biology, 5 (1). p. 1305. ISSN 2399-3642

Salian-Mehta, Smita, Poling, Jerry, Birkebak, Joanne, Rensing, Susanne, Carosino, Chris, Santos, Rosemary, West, Wanda, Adams, Khary, Orsted, Kathy, Fillman-Holliday, Denise and Burns, Monika (2022) Non-Human (NHP) husbandry and impact on NHP health: outcomes from a DruSafe/3Rs industrial benchmark survey. International Journal of Toxicology. ISSN 1091-58181092-874X

Salvi, Amrita, Young, Alexandria N., Huntsman, Andrew C., Pergrande, Melissa, Korkmaz, Melissa A., Mize, Brittney K., Zhang, Xiaoli, Ratia, Kiira, Shelton IV, Claude, Brittain, Scott, Schirle, Markus, Thomas, Jason, Aldritch, Leslie N., Cologna, Stephanie M., Fuchs, James R. and Burdette, Joanna E. (2022) PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancer. Cell death & disease, 13 (1). p. 45. ISSN 2041-4889

Sangana, Ramachandra, Mittal, Hemant, Barsainya, Sarita, Hoermann, Aldo, Borde, Parag Prakash, Zhang, Jie, Valentin, Marie-Anne and KALLURI, SAMPATH (2022) A randomized clinical study evaluating the therapeutic equivalence of vildagliptin 100 mg once daily modified release to 50 mg twice daily immediate release formulations. Diabetes & metabolic syndrome clinical research & reviews., 16 (3). ISSN 18714021

Saxer, Franziska (2022) People of TM: Video of Franziska Saxer. YouTube.

Schiller, Hilmar, Huth, Felix, Schuhler, Carole, Drollmann, Anton Franz, Kaul, Martin, Woessner, Ralph, Shah, Bharti, Weis, Wendy and End, Peter (2022) Novel Bruton's tyrosine kinase inhibitor remibrutinib: Assessment of drug-drug interaction potential as a perpetrator of cytochrome P450 enzymes and drug transporters and the impact of covalent binding on possible drug interactions. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 172. p. 106155. ISSN 1879-0720

Schiller, Hilmar, Huth, Felix, Schuhler, Carole, Drollmann, Anton Franz, Kaul, Martin, Woessner, Ralph, Shah, Bharti, Weis, Wendy and End, Peter (2022) Novel Bruton’s tyrosine kinase inhibitor remibrutinib: Assessment of drug-drug interaction potential as a perpetrator of cytochrome P450 enzymes and drug transporters and the impact of covalent binding on possible drug interactions. European journal of pharmaceutical sciences, 172. ISSN 09280987

Schmelzer, Bernhard and Sutter, Marc (2022) Tolerance Interval Approach for the Determination of Overfill of Liquid Parenteral Drug Products. PDA journal of pharmaceutical science and technology, 77 (3). pp. 181-196. ISSN 1948-2124

Schoeberl, Birgit and Kearns, Jeff (2022) Navigating Between Right, Wrong, and Relevant: The Use of Mathematical Modeling in Preclinical Decision Making. Frontiers in pharmacology, 13. p. 860881. ISSN 1663-9812

Schuetz, Stefan, Bergsdorf, Christian, Goretzki, Benedikt, Lingel, Andreas, Renatus, Martin, Gossert, Alvar and Jahnke, Wolfgang (2022) The Disordered MAX N-terminus Modulates DNA Binding of the Transcription Factor MYC:MAX. Journal of molecular biology, 434 (22). p. 167833. ISSN 1089-8638

Schwab, Nathalie, Nienhold, Ronny, Henkel, Maurice, Baschong, Albert, Graber, Anne, Frank, Angela, Mensah, Nadine, Koike, Jacqueline, Hernach, Claudia, Sachs, Melanie, Willi, Niels, Zsikla, Veronika, Junt, Tobias and Mertz, Kirsten (2022) COVID-19 Autopsies Reveal Underreporting of SARS-CoV-2 Infection and Scarcity of Co-infections. Frontiers in medicine, 9. p. 868954. ISSN 2296-858X

Scorrano, Fabrizio (2022) A New Feeder Device to Provide Cleaner and Accessible Diet Gel to Laboratory Mice. Laboratory Animal Science Professional. pp. 50-52.

Scuderi, Maria, Dermol-Cerne, Janja, Amaral da Silva, Clarissa, Muralidharan, Aswin, Boukany, Pouyan E. and Rems, Lea (2022) Models of electroporation and the associated transmembrane molecular transport should be revisited. Bioelectrochemistry, 147. p. 108216. ISSN 15675394

Sechaud, Romain, Sinclair, Karen, Grosch, Kai and Pathak, Dhrubajyoti (2022) Evaluation of drug-drug interactions between midostaurin and strong CYP3A4 inhibitors in patients with FLT-3-mutated acute myeloid leukemia (AML). Cancer chemotherapy and pharmacology, 90 (1). pp. 19-27. ISSN 1432-0843

Seelinger, Felix, Wittkopp, Felix, von Hirschheydt, Thomas and Frech, Christian (2022) Anti-Langmuir elution behavior of a bispecific monoclonal antibody in cation exchange chromatography: Mechanistic modeling using a pH-dependent Self-Association Steric Mass Action isotherm. Journal of chromatography A, 1689 (1689). unknown-unknown. ISSN 1873-3778; 0021-9673

Segal, Florencia (2022) People of TM: Video of Florencia Segal. LinkedIn.

Seror, Raphaele, Baron, Gabriel, Camus, Marine, Cornec, Divi, Perrodeau, Elodie, Bowman, Simon, Bombardieri, Michele, Bootsma, Hendrika, Gottenberg, Jaccques-Eric, Fisher, Benjamin, Hueber, Wolfgang, van Roon, Joel, Devauchelle-Pensec, Valerie, Gergely, Peter, Mariette, Xavier and Porcher, Raphael (2022) Development and preliminary validation of the Sjögren’s Tool for Assessing Response (STAR): a consensual composite score for assessing treatment effect in primary Sjögren’s syndrome. Annals of the rheumatic diseases : ARD, Online (Online). Online-Online. ISSN Online ahead of print

Shabani, Shaban, Bourke, Alan, Muaremi, Amir, O'Keeffe, Kate, Argent, Rob, Caulfield, Brian, Praestgaard, Jens, Scotti, Celeste and Walsh, Lorcan (2022) An Automatic Foot and Shank IMU Synchronization Algorithm: Proof-of-concept. IEEE Engineering in Medicine and Biology Society (EMBC) 2022 Conference.

Shaqra, Ala, Zvornicanin, Sarah, Qiu, Huang, Lockbaum, Gordon, Knapp, Mark, Tandeske, Laura, Barkan, Dave, Flynn, Julia, Bolon, Daniel, Moquin, Stephanie, Dovala, Dustin, Yilmaz, Nese and Schiffer, Celia (2022) Defining the substrate envelope of SARS-CoV-2 main protease to predict and avoid drug resistance. Nature communications, 13 (1). p. 3556. ISSN 2041-1723

Sivasubramanian, Rama, Sunkara, Gangadhar, Karan, Rajesh, Zhou, Wei, Zhang, Yiming and Sangana, Ramachandra (2022) The bioequivalence between pediatric-centric valsartan oral solution and extemporaneous suspension formulations. Clinical Pharmacology in Drug Development, 11 (7). pp. 843-848. ISSN 2160-763X2160-7648

Skolnik, Suzanne, Barrett, Jaclyn, Yang, Wenzhan, Belliveau, Lisa and Patros, Kellyn (2022) Discovery solubility measurement and assessment with drug development in mind. Drug discovery today. ISSN 13596446

Slieker, Rocerick C, Donnelly, Louise A, Jennings, Lori, Hart, Leen M, Pearson, Ewan R and Rutter, Guy A (2022) Novel biomarkers for glycaemic deterioration in type 2 diabetes: an IMI RHAPSODY study. https://www.medrxiv.org/content/10.1101/2021.04.22.21255625v1.

Snyder, Jennifer (2022) We Support each other to Develop and Grow at Novartis. Biopharma Asia https://biopharma-asia.com/featured-careers / also published in Biopharma Careers https://biopharma-careers.com/ .

Spencer, Sarah, Chung, Jessie R., Belongia, Edward A., Sundaram, Maria, Meece, Jennifer, Coleman, Laura A., Zimmerman, Richard K., Nowalk, Mary Patricia, Moehling Geffel, Krissy, Ross, Ted, Carter, Chalise E., Shay, David, Levine, Min, Liepkalns, Justine, Kim, Jin Hyang, Sambhara, Suryaprakash, Thompson, Mark G. and Flannery, Brendan (2022) Impact of diabetes status on immunogenicity of trivalent inactivated influenza vaccine in older adults. Influenza and Other Respiratory Viruses, 16 (3). pp. 562-567. ISSN 1750-2640

Stange, Carolin, Sánchez-Reyes, Gabriela, Graalfs, Heiner and Frech, Christian (2022) Influence of ligand density variations on the two peak elution behavior of a monoclonal antibody in cation exchange chromatography. Journal of Chromatography A, 1680. ISSN 00219673

Statelova, Marina, Vertzoni, Maria and Kourentas, Alexandros (2022) Simulation of intraluminal performance of lipophilic weak bases in fasted healthy adults using the DDDPlusTM Artificial Stomach Duodenum model. The AAPS journal, 24 (5).

Stocker, Stephan, Rogue, Vincent, Steib-Lauer, Caroline, Haecker, Hans-Georg, Spickermann, Dirk, Hirsch, Stefan, Dhareshwar, Sundeep, Claudia, Vicente Martin and Manel, Bautista (2022) Twin-screw melt granulation based high drug load tablet formulation. An industrial perspective on process transfer to a commercial manufacturing site. Drug development and industrial pharmacy, https:. pp. 1-15. ISSN 1520-5762; 0363-9045

Sun, Sophie, Sechidis, Kostas, Chen, Yao, Lu, Jiarui, Ma, Chong, Mirshani, Ardalan, Ohlssen, David, Vandemeulebroecke, Marc and Bornkamp, Bjoern (2022) Comparing algorithms for characterizing treatment effect heterogeneity in randomized trials. Biometrical journal. Biometrische Zeitschrift. ISSN 1521-4036

Sy, Sherwin, Tanaka, Chiaki and Grosch, Kai (2022) Population Pharmacokinetics and Pharmacodynamics of Crizanlizumab in Healthy Subjects and Patients with Sickle Cell Disease. Clinical pharmacokinetics. ISSN 1179-1926

Sykes, David A, Jimenez-Roses, Mireia, Reilly, John, Fairhurst, Robin, Charlton, Steven J and Veprintsev, Dmitry (2022) Exploring the kinetic selectivity of drugs targeting the beta1-adrenoceptor. Molecular pharmacology, 10 (4). pp. 1-14. ISSN 2052-1707

T

Taskar, Kunal, Yang, Xinning, Neuhoff, Sibylle, Patel, Mitesh, Yoshida, Kenta, Paine, Mary, Brouwer, Kim, Chu, Xiaoyan, Sugiyama, Yuichi, Cook, Jack, Polli, Joseph, Hanna, Imad, Lai, Yurong and Zamek-Gliszczynski, Maciej (2022) Clinical relevance of hepatic and renal P-gp/BCRP inhibition of drugs: An International Transporter Consortium perspective. Clinical pharmacology and therapeutics. ISSN 1532-6535

Tassano, Erika, Moore, Charles, Dussauge, Solene, Vargas, Alexandra and Snajdrova, Radka (2022) Discovery of novel Fe(II)/α-ketoglutarate-dependent dioxygenases for oxidation of L-proline. Organic Process Research & Development. ISSN 1083-61601520-586X

Taubenschmid-Stowers, Jasmin, Krauditsch, Christian, Studer, Christian, Lämmerer, Anna, Lötsch, Daniela, Gojo, Johannes, Widhalm, Georg, Peyrl, Andreas, Spiegl-Kreinecker, Sabine, Berger, Walter, Hoepfner, Dominic, Bian, Shan, Knoblich, Juergen, Elling, Ulrich and Penninger, Josef M. (2022) A whole genome scan for Artemisinin cytotoxicity reveals a novel therapy for human brain cancer. EMBO molecular medicine, e16959 (e16959). pp. 1-20. ISSN 1757-4684; 1757-4676

Tia , Byer and Richter, Susanne (2022) Future Directions for Accelerated Upstream Bioprocessing. Cell Content hub: https://www.oxfordglobal.co.uk/cell/, n.a. (n.a.). n.a.-n.a.. ISSN n.a.

Tin, Adrienne, Jennings, Lori, Gudnason, Vilmundur and Mosley, Thomas H (2022) Proteomic analysis identifies circulating proteins associated with plasma amyloid βeta and incident dementia. Biological Psychiatry Global Open Science. ISSN 26671743

Tjaden, Amelie, Chaikuad, Apirat, Kowarz, Eric, Marschalek, Rolf, Knapp, Stefan, Schröder, Martin and Müller, Susanne (2022) Image-Based Annotation of Chemogenomic Libraries for Phenotypic Screening. Molecules (Basel, Switzerland), 27 (4). ISSN 1420-3049

Torres, Julia Baguña, Roodselaar, Jay, Sealey, Megan, ziehn, marina, Bigaud, Marc, Kneuer, Rainer, Leppert, David, Weckbecker, Gisbert, Cornelissen, Bart and Anthony, Anthony (2022) Distribution and Efficacy of Ofatumumab and Ocrelizumab in Humanized CD20 Mice Following Subcutaneous or Intravenous Administration. Frontiers in Immunology: Multiple Sclerosis and Neuroimmunology’..

Tsai, Kaitlyn, Stojković, Vanja, Lee, D John, Young, Iris D, Szal, Teresa, Klepacki, Dorota, Vázquez-Laslop, Nora, Mankin, Alexander S, Fraser, James S and Fujimori, Danica Galonić (2022) Structural basis for context-specific inhibition of translation by oxazolidinone antibiotics. Nature structural & molecular biology, 29 (2). pp. 162-171. ISSN 1545-9985

Tsai, Kaitlyn, Stojković, Vanja, Noda-Garcia, Lianet, Young, Iris D, Myasnikov, Alexander G, Kleinman, Jordan, Palla, Ali, Floor, Stephen N, Frost, Adam, Fraser, James S, Tawfik, Dan S and Fujimori, Danica Galonić (2022) Directed evolution of the rRNA methylating enzyme Cfr reveals molecular basis of antibiotic resistance. eLife, 11. ISSN 2050-084X

Tuckwell, Danny (2022) People of TM: Video of Danny Tuckwell. YouTube.

Tukov, Francis, Mansfield, Keith, Milton, Mark, Meseck, Emily, Penraat, Kelley, Hartmann, Andreas and Chand, Deepa (2022) Single-Dose Intrathecal Dorsal Root Ganglia Toxicity of Onasemnogene Abeparvovec in Cynomolgus Monkeys. Human gene therapy. ISSN 1557-7422

U

Uddin, Erfan Muhammad, Eisenmann, Eric D, Huang, Kevin M, Garrison, Dominique A, Talebi, Zahra, Gibson, Alice A, Jin, Yan, Nepal, Mahesh, Bonilla, Ingrid M, Fu, Qiang, Millar, Alec, Tarasov, Mikhail, Jay, Christopher E, Cui, Xiaoming, Einolf, Heidi, Pelis, Ryan, Smith, Sakima A, Radwanski, Przemyslaw, Sweet, Douglas H, Konig, Jorg, Fromm, Martin F, Carnes, Cynthia A, Hu, Shuiying and Sparreboom, Alex (2022) Contribution of MATE1 to Dofetilide-Induced Proarrhythmia. International journal of molecular sciences, 23. ISSN 1422-0067

Ullrich, Thomas, Teixeira-Fouchard, Sylvie, Broennimann, Valerie, Stiefl, Nikolaus, Head, Victoria, Kramer, Ina, Guth-Gundel, Sabine, Arista, Luca and Weiler, Sven (2022) Discovery of a novel 2-aminopyrazine-3-carboxamide as a potent and selective inhibitor of Activin Receptor-Like Kinase-2 (ALK2) for the treatment of fibrodysplasia ossificans progressiva. Bioorganic & medicinal chemistry letters. ISSN 1464-3405

Ungricht, Rosemarie, Guibbal, Laure, Lasbennes-Eckerlen, Marie-Christine, Orsini, Vanessa, Beibel, Martin, Waldt, Annick, Cuttat-Theurillat, Rachel, Carbone, Walter, Basler, Anne, Roma, Guglielmo, Nigsch, Florian, Tchorz, Jan, Hoepfner, Dominic and Hoppe, Philipp (2022) Genome-wide screening in human kidney organoids identifies novel aspects of nephrogenesis. Cell stem cell, 29 (1). p. 160. ISSN 19345909

V

Vicart, Axel (2022) People of TM: Video of Axel Vicart. YouTube.

Villois, Alessia, Capasso Palmiero, Umberto, Mathur, Prerit, Perone, Gaia, Schneider, Timo, Li, Lunna, Salvalaglio, Matteo, deMello, Andrew, Stavrakis, Stavros and Arosio, Paolo (2022) Droplet Microfluidics for the Label-Free Extraction of Complete Phase Diagrams and Kinetics of Liquid-Liquid Phase Separation in Finite Volumes. Small (Weinheim an der Bergstrasse, Germany), 18 (46). e2202606. ISSN 1613-6829

Voss, Moritz, Hüppi, Sean, Schaub, Daniela, Hayashi, Takahiro, Ligibel, Mathieu, Sager, Emine, Schroer, Kirsten, Snajdrova, Radka and Buller, Rebecca (2022) Enzyme engineering enables inversion of substrate stereopreference of the halogenase WelO5*. ChemCatChem.. ISSN 1867-3899

Vulin, Milica, Sethi, Atul, Jehanno, Charlie, Obradovic, Milan, Correia, Ana, Pinto Do Couto E Silva, Joana, Auf der Maur, Priska, Schmidt, Alexander, Coissieux, Marie-May, Munst, Simone, Preca, Tiberius, Diepenbruck, Maren, Volkmann, Katrin, Sauteur, Loic, Britschgi, Adrian, Unterreiner, Vincent, Galuba, Olaf, Claerr, Isabelle, Lopez Romero, Sandra, Galli, Giorgio, Baeschlin, Daniel, Okamoto, Ryoko, Soysal, Savas, Mechera, Robert, Weber, Walter, Radimerski, Thomas and Bentires-Alj, Mohamed (2022) A high-throughput drug screen reveals means to differentiate triple-negative breast cancer. Oncogene. ISSN 1476-5594

Vulpetti, Anna, Lingel, Andreas, Dalvit, Claudio, Schiering, Nikolaus, Oberer, Lukas, Henry, Christelle and Lu, Yipin (2022) Efficient Screening of Target-Specific Selected Compounds in Mixtures by 19F NMR Binding Assay with Predicted 19F NMR Chemical Shifts. ChemMedChem : chemistry enabling drug discovery. ISSN 1860-7187; 1860-7179

W

Walles, Markus (2022) Meeting report of the second European Biotransformation Workshop. Xenobiotica, 52 (4). pp. 426-431.

Walles, Markus (2022) A Cross Company Perspective on the Assessment of Therapeutic Protein Biotransformation. Drug metabolism and disposition, June.

Wargenau, Manfred, Reidemeister, Sibylle, Klingmann, Ingrid and Klingmann , Viviane (2022) A composite endpoint for acceptability evaluation of oral drug formulations in the pediatric population. Therapeutic Innovation & Regulatory Science (TIRS) , 2022.

Weeks, Ryan, Zhou, Xin, Yuan, Tina and Zhang, Jin (2022) Fluorescent Biosensor for Measuring Ras Activity in Living Cells. Journal of the American Chemical Society, 144 (38). pp. 17432-17440. ISSN 1520-5126

Weeks, Ryan, Zhou, Xin, Yuan, Tina and Zhang, Jin (2022) A fluorescent biosensor for measuring Ras activity in living cells. Journal of the American Chemical Society JACS.. ISSN 0002-78631520-5126

Weisberg, Ellen, Chowdhury, Basudev, Meng, Chengcheng, Case, Abigail, Ni, Wei, Garg, Swati, Sattler, Martin, Azab, Abdel Kareem, Sun, Jennifer, Muz, Barbara, Sanchez, Dana, Toure, Anthia, Stone, Richard, Galinsky, Ilene, Winer, Eric, Gleim, Scott, Gkountela, Sofia, Kedves, Alexia, Harrington, Edmund, Abrams, Tinya, Zoller, Thomas, Vaupel, Andrea, Manley, Paul, Faller, Michael, Chung, BoYee, Chen, Xin, Busenhart, Philipp, Stephan, Christine, Calkins, Keith, Bonenfant, Debora, Thoma, Claudio, Forrester, William and Griffin, James (2022) BRD9 degraders as chemosensitizers in acute leukemia and multiple myeloma. Blood cancer journal, 12 (7). p. 110. ISSN 2044-5385

Weiss, Andreas, Lorthiois, Edwige, Barys, Louise, Beyer, Kim, Bomio-Confaglia, Claudio, Burks, Heather, Chen, Xueying, Cui, Xiaoming, de Kanter, Ruben, Dharmarajan, Lekshmi, Fedele, Carmine, Gerspacher, Marc, Guthy, Daniel Alexander, Head, Victoria, Jaeger, Ashley, Jimenez Nunez, Eloisa, Kearns, Jeff, Leblanc, Catherine, Maira, Michel, Murphy, Jason, Oakman, Helen, Ostermann, Nils, Ottl, Johannes, Rigollier, Pascal, Roman, Danielle, Schnell, Christian, Sedrani, Richard, Shimizu, Toshio, Stringer, Rowan, Vaupel, Andrea, Voshol, Johannes, Wessels, Peter, Widmer, Toni, Wilcken, Rainer, Xu, Kun, Zecri, Frederic, Farago, Anna, Cotesta, Simona and Brachmann, Saskia (2022) Discovery, preclinical characterization, and early clinical activity of JDQ443, a structurally novel, highly potent, selective covalent oral inhibitor of KRASG12C. Discovery, preclinical characterization, and early clinical activity of JDQ443, a structurally novel, highly potent, selective covalent oral inhibitor of KRASG12C.

Wilbaux, Melanie, Demanse, David, Gu, Gary, Jullion, Astrid, Myers, Andrea, Katsanou, Vasiliki and Meille, Christophe (2022) Contribution of machine learning to tumor growth inhibition modeling for hepatocellular carcinoma patients under Roblitinib (FGF401) drug treatment. CPT: pharmacometrics & systems pharmacology. ISSN 2163-8306

Wolf, Babette, Piksa, Mateusz, Voedisch, Bernd, Patoux, Agnes, Besson, Thierry, Schindler, Patrick, Cordier, Valerie, Perrot, Ludovic, Brees, Dominique and Kammueller, Michael (2022) Therapeutic antibody glycosylation impacts antigen recognition and immunogenicity. Immunology. ISSN 1365-2567

Y

Yang, Tong-yuan, Braun, Manuela, Wibke, Lembke, McBlane, Fraser, Kamerud, John, DeWall, Stephen, Tarcsa, Edit, Fang, Xiaodong, Hofer, Lena, Kavita, Uma, Upreti, Vijay V., Gupta, Swati, Loo, LiNa, Johnson, Alison J., Jawa, Vibha, Chandode, Rakesh Kantilal, Vinzing, Maya and Xia, Cindy Q. (2022) Immunogenicity Assessment of AAV-based Gene Therapies: An IQ Consortium Industry White Paper. Molecular therapy - methods and clinical development, 26. pp. 471-494. ISSN 2329-0501

Z

Zaghlool, Shaza B., Gudmundsdottir, Valborg, Jennings, Lori, Gudnason, Vilmundar and Suhre, Karsten (2022) Metabolic and proteomic signatures of type 2 diabetes subtypes in an Arab population. Nature communications, 13 (1). p. 7121. ISSN 2041-1723

Zevnik, Branko, Jerchow, Boris and Buch, Thorsten (2022) 3R measures in facilities for the production of genetically modified rodents. Lab animal, 51 (6). pp. 162-177. ISSN 1548-4475

Zevnik, Branko, Jerchow, Boris and Buch, Thorsten (2022) 3R Measures in facilities for the production of genetically modified rodents. Lab animal, 51 (6). pp. 162-177. ISSN 1548-4475; 0093-7355

Zhang, Luqing, Cunningham, Jonathan, Claggett, Brian, Jacob, Jaison, Mendelson, Mike, Serrano Fernandez, Pablo, Kaiser, Sergio, Yates, Denise, Healey, Margaret, Chen, Chien-Wei, Turner, Gordon, Patel-Murray, Natasha, Zhao, Faye, Beste, Michael, Laramie, Jason, Abraham, William, Jhund, Pardeep, Kober, Lars, Packer, Milton, Rouleau, Jean, Zile, Michael, Prescott, Margaret, Lefkowitz, Martin, McMurray, John, Solomon, Scott and Chutkow, William (2022) Aptamer Proteomics for Biomarker Discovery in Heart Failure With Reduced Ejection Fraction. Circulation, 146 (18). pp. 1411-1414. ISSN 1524-4539

Zhang, Luqing, Cunningham, Jonathan, Claggett, Brian, Jacob, Jaison, Mendelson, Mike, Serrano Fernandez, Pablo, Kaiser, Sergio, Yates, Denise, Healey, Margaret, Chen, Chien-Wei, Turner, Gordon, Patel-Murray, Natasha, Zhao, Faye, Beste, Michael, Laramie, Jason, Abraham, William, Jhund, Pardeep, Kober, Lars, Packer, Milton, Rouleau, Jean, Zile, Michael, Prescott, Margaret, Lefkowitz, Martin, McMurray, John, Solomon, Scott and Chutkow, William (2022) Aptamer Proteomics for Biomarker Discovery in Heart Failure with Reduced Ejection Fraction. Circulation. ISSN 1524-4539

Zhou, Yu and Wang, Yueju (2022) Sample Preparation Matters for Peptide Mapping to Evaluate Deamidation of Adeno-Associated Virus Capsid Proteins Using Liquid Chromatography–Tandem Mass Spectrometry. Human Gene Therapy, 33 (15 and). pp. 821-828.

Zula, Ales, Zidar, Mitja, Lebar, Blaz, Proj, Matic, Strasek, Nika, Gobec, Stanislav and Milicic, Goran (2022) Discovery of compounds with viscosity-reducing effects on biopharmaceutical formulations with monoclonal antibodies. Computational and structural biotechnology journal, 20. pp. 5420-5429. ISSN 20010370

Ž

Žuntar, Timotej, Ličen, Matjaž, Kuzman, Drago and Osterman, Natan (2022) Real-time imaging of monoclonal antibody film reconstitution after mechanical stress at the air-liquid interface by Brewster angle microscopy. Colloids and surfaces. B, Biointerfaces, 218. p. 112757. ISSN 1873-4367

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