Browse views: by Year, by Function, by GLF, by Subfunction, by Conference, by Journal

Items where Year is 2021

Up a level
Export as [feed] RSS
Group by: Creators | Item Type | No Grouping
Jump to: A | B | C | D | E | F | G | H | I | J | K | L | M | N | P | R | S | T | U | V | W | Z
Number of items: 112.

A

Aeffner, Famke and Turner, Oliver and Sing, Tobias (2021) Special Issue on Digital Pathology, Tissue Image Analysis, Artificial Intelligence, and Machine Learning: Approximation of the Effect of Novel Technologies on Toxicologic Pathology. Toxicologic Pathology, Volume (4). pp. 705-708. ISSN 15331601

Auberson, Yves (2021) Reflections on 2018-2020. EFMC Yearbook, 2021. pp. 3-4.

Axford, Jake and Briner, Karin and Cheung, Atwood and Dales, Natalie and Hurley, Timothy and Jain, Monish and Sung, Moo and Manchester, John and Hamann, Lawrence and Chin, Donovan and Shin, Youngah and Sivasankaran, Rajeev (2021) Use of Intramolecular 1,5-sulfur-oxygen and 1,5-sulfur-halogen interactions in the design of N-methyl-5-aryl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine SMN2 splicing modulators. Journal of Medicinal Chemistry. ISSN 0022-26231520-4804

B

Baczyk, Paulina and Wyss, Brigitte and Widmer, Jasmin and Hartmann, Steffen and Wassmann, Paul and Lobo, Susana and Jesus, Lídia and Gomes, Joana and Batista, Ana (2021) Stability liabilities of biotherapeutic proteins: early assessment as mitigation strategy. Journal of pharmaceutical and biomedical analysis, 192. pp. 1-15. ISSN 1873-264X; 0731-7085

Barabas, Amanda J and Soini, Helena A and Novotny, Milos V and Williams, David R and Desmond, Jacob A and Lucas, Jeffrey R and Erasmus, Marisa A and Cheng, Heng-Wei and Gaskill, Brianna N (2021) Compounds from plantar foot sweat, nesting material, and urine show strain patterns associated with agonistic and affiliative behaviors in group housed male mice, Mus musculus. PloS one, 16 (5). e0251416. ISSN 1932-6203

Baran, Szczepan and Lim, Maria A. and Do, Johnny P. and Stolyar, Polina and Rabe, Mark D. and Schaevitz, Laura R. and Cadena, Samuel (2021) Digital biomarkers enable automated, longitudinal monitoring in a mouse model of aging. The journals of gerontology. Series A, Biological sciences and medical sciences. ISSN 1758535X

Boyle, Molly and Bennet, Bindu and Houle, Christopher D. and Sura, Radhakrishna and Colman, Karyn and Romeike, Annette and Frisk, Anna-Lena and Garcia, Begonya and Elmore, Susan A. (2021) Publication Categories in Toxicologic Pathology. Toxicologic Pathology. ISSN 15331601

C

Canham, Steve and Jenkins, Jeremy and Forrester, William and Hild, Marc and Ambrose, Jessi and Sigoillot, Frederic and Gleim, Scott and Cobos-Correa, Amanda and Wang, Ying and Eggimann, Fabian and Moore, Charles and Mapa, Felipa and Burks, Heather and Roma, Guglielmo and Krastel, Philipp and Tallarico, John and Nomura, Daniel and Fisher, David and Zhang, Lydia and Cho, Hyelim and Shen, Qiong and Okumura, Mikiko and Kawakami, Akinori and Miller, Howard and Dix, Ina and Ross, Nathan (2021) CYP27A1 dependent anti-melanoma activity of limonoid natural products targets mitochondrial metabolism. Cell chemical biology. ISSN 24519456

Carballido, Jose and Spits, Hergen (2021) Legends of allergy and immunology: Jan E. de Vries. Allergy. ISSN 13989995

Carbonneau, Seth and Sharma, Sujata and Peng, Liaomin and Rajan, Vaisakh and Hainzl, Dominik and Henault, Martin and Yang, Chian and Hale, Jacob and Shulok, Janine and Tallarico, John and Porter, Jeffrey and Brogdon, Jennifer and Dranoff, Glenn and Bradner, Jay and Hild, Marc and Guimaraes, Carla (2021) An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity. Cell Chemical Biology. ISSN 24519448

Cassaro, A and Grillo, G and Esposito, I and Reda, G and Cairoli, R and Beghini, A and Notaro, M and Gliozzo, J and Trojani, A and Valentini, G and Di Camillo, B (2021) FZD6 triggers Wnt–signalling driven by WNT10BIVS1 expression and highlights new targets in T cell acute lymphoblastic leukemia. Hematological oncology. ISSN 1099-1069

Christophe, Pellefigues and Karmella, Naidoo and Palak, Mehta and Alfonso , Schmidt and Ferdinand, Jagot and Roussel, Elsa and Cait, Alissa and Bibek, Yumnam and Sally, Chappell and Meijlink, Kimberly and Mali, Chamberis and Jean, Jiang and Gavin, Painter and Filbey, Kara and Uluckan, Ozge and Olivier, Gasser and Graham, LeGros (2021) Basophils promote barrier dysfunction and resolution in the atopic skin. Journal of Allergy and Clinical Immunology. ISSN 10976825

D

Dawson King, Janet and Vogelsanger, Melanie (2021) Cantharidin-induced skin blister as an in vivo model of inflammation. Current Protocols in Pharmacology , 1 (e49). pp. 1-14.

Diener, John and Mowbray, Sarah and Huang, WaanJeng and Yowe, David and Xu, Jian and Caplan, Shari and Misra, Abhay and Kapur, Ankur and Shapiro, Jeffrey and Ke, Xiaoling and Wu, Xiaoping and Bose, Avirup and Panza, Darrell and Chen, Min and Beaulieu, Valerie and Gao, Jiaping (2021) FGF21 Normalizes Plasma Glucose in Mouse Models of Type 1 Diabetes and Insulin Receptor Dysfunction. bioRxiv. pp. 1-19. ISSN https://doi.org/10.1101/2021.01.04.425295

Dittrich, Birger (2021) On modelling disordered crystal structures through restraints from molecule-in-cluster computations,and distinguishing static and dynamic disorder. IUCrJ, International Union of Crystallography Journal , 8. pp. 305-318. ISSN 2052-2525

Dodd, Stephanie (2021) Use of PBPK Modeling for Predicting Drug-Food Interactions: Successful prediction using a middle-out approach. AAPS PharmSci, 23 (12). ISSN 1550-7416/21/0000-0001/0

E

Elo, Petri and Li, Xiang-Guo and Liljenbäck, Heidi and Gardberg, Maria and Moisio, Olli and Miner, Maxwell and Virta, Jenni and Saraste, Antti and Srinivasarao, Madduri and Pugh, Michael and Low, Philip and Knuuti, Juhani and Jalkanen, Sirpa and Airas, Laura and Lu, June and Roivainen, Anne (2021) Efficacy and tolerability of a folic acid derivative of aminopterin in a rat focal model of multiple sclerosis. J Neuroinflammation, 18 (30).

F

Fanale, Salvatore and Emmons, Kayla and Gunderson, Andrew (2021) WDII Unpacking and Startup Video. N/A, n/a (n/a). n/a-n/a. ISSN n/a

Fanous, Marina and Bitar, Malak and Gold, Sarah and Sobczuk, Adam and Hirsch, Stefan and Ogorka, Joerg and Imanidis, Georgios (2021) Immediate Release 3D-Printed Dosage Forms for Poorly Soluble Drugs: Development and Exploration of Morphology-Dissolution Relationship. International journal of pharmaceutics, 26. p. 120417. ISSN DOI: 10.1016/j.ijpharm.2021.120417

Filipponi, Paolo and Martin, Benjamin and Knochel, Paul and Heinz, Benjamin and Djukanovic, Dimitrije (2021) Regioselective Difunctionalization of Pyridines via 3,4-Pyridynes. Chemical Science, 12. pp. 6143-6147. ISSN https://doi.org/10.1039/D1SC01208H

Frederiksen, Mathias (2021) The kinase chemogenomic set (KCGS): An open science resource for kinase vulnerability identification. International Journal of Molecular Sciences, 22 (2). pp. 1-18. ISSN 14220067

Freund, Ernst and Meyer, Daniel and Schneider, Nadine and Lozac'h, Marie-Anne and Schroeder, Harald and Cynar, Cagatay and Schlotterbeck, Goetz and Wagner, Beatrix (2021) Automated chiral method screening – Evaluation of generated chromatographic data sets to further optimize screening efficiency. Journal of Chromatography A, 1644. ISSN 0021-9673

G

Gallou, Fabrice (2021) Late-stage cyanation of aryl/heteroaryl halides using ppm levels of a bidentate phosphine-derived palladacycle in water. ChemCatChem., 13 (1). pp. 212-216. ISSN 1867-3899; 1867-3880

Gallou, Fabrice (2021) Mild and robust Stille reactions in water using ppm levels of a new triphenylphosphine-based palladacycle. Angewandte Chemie. International edition, 60 (9). pp. 4158-4163.

Gallou, Fabrice (2021) Nanochannels in Photoactive Cu(I) Polymer for Selective Oxidations in Aqueous Micelles. ACS Sustainable Chem. Eng, 9 (7). pp. 2854-2860.

Gallou, Fabrice (2021) Safe, Scalable, Inexpensive, and Mild Nickel-Catalyzed Migita-like C–S Cross-Couplings in Recyclable Water. Angewandte Chemie. International edition, 60 (7). pp. 3708-3713.

Gallou, Fabrice (2021) “TPG-lite”: A new, simplified “designer” surfactant for general use in synthesis under micellar catalysis conditions in recyclable water. Tetrahedron.

Gallou, Fabrice (2021) Water in organic chemistry:from our worst enemy to our best friend. Chemical science, 12. pp. 4237-4266.

Gallou, Fabrice (2021) Water-Sculpting of a Heterogeneous Nanoparticle Pre-catalyst for Mizoroki-Heck Couplings Under Micellar Catalysis Conditions. Journal of the American Chemical Society JACS., 143 (9). pp. 3373-3382.

Gallou, Fabrice and Plummer, Scott (2021) Nanochannels in Photoactive Polymeric Cu(I) Compatible for Efficient Micellar Catalysis: Sustainable Aerobic Oxidations of Alcohols in Water. ACS Sustainable Chem. Eng., 9 (7). pp. 2854-2860.

Glowienke, Susanne (2021) Use of less-than-lifetime (LTL) durational limits for nitrosamines: Case study of N-Nitrosodiethylamine (NDEA). Regulatory Toxicology and Pharmacology, 123. ISSN 10960295

Goebel, Mathias and Dos Reis Rodrigues, Rui Claudio and Pampel, Lars and Rapp, Johanna and Shultz, Joseph and Cui, Huanchun (2021) Flow management strategies for a connected purification process. Biotechnology and bioengineering. ISSN 10970290

Golosov, Andrei and Flyer, Alec and Amin, Jakal and Babu, Charles and Gampe, Christian and Li, Jingzhou and Liu, Eugene and Nakajima, Katsumasa and Nettleton, David and Patel, Tej and Reid, Patrick and Yang, Lihua and Monovich, Lauren (2021) Design of thioether cyclic peptide scaffolds with passive permeability and oral exposure. Journal of medicinal chemistry, 64 (5). pp. 2622-2633.

Grass, Verena and Begue, Damien and Cordo, Valentina and Holzer, Laura and Martinuzzi-Duboc, Laetitia and Buhles, Alexandra and Kerr, Grainne and Barbosa, Ines and Naumann, Ulrike and Piquet, Michelle and Ruddy, David and Tordella, Luca and Weiss, Andreas and Ferretti, Stephane Raymond and Almeida, Reinaldo and Bonenfant, Debora and Galli, Giorgio (2021) Therapeutic Assessment of Targeting ASNS Combined with l-Asparaginase Treatment in Solid Tumors and Investigation of Resistance Mechanisms. ACS Pharmacology and Translational Sciences.

Guerreiro, Nelson and Jullion, Astrid and Ferretti, Stephane Raymond and Fabre, Claire and Meille, Christophe (2021) Translational Modeling of Anticancer Efficacy to Predict Clinical Outcomes in a First-in-Human Phase 1 Study of MDM2 Inhibitor HDM201. AAPS Journal, 23 (2). ISSN 15507416

Gurinovich, Anastasia and Song, Zeyuan and Zhang, William and Federico, Anthony and Monti, Stefano and Anderson, Stacy L and Jennings, Lori and Barzilai, Nir and Millman, Sofiya and Perls, Thomas T and Sebastian, Paola (2021) Effect of longevity genetic variants on the molecular aging rate. GeroScience. ISSN 25092723

H

Hadjikyriacou, Andrea and Concannon, John and Sigoillot, Frederic and Antczak, Christophe and Jenkins, Jeremy and Nyfeler, Beat and Jain, Rishi and Tallarico, John and Canham, Steve (2021) Multi-Species Phenotypic Screening across Disease Models of Mucolipidosis Type IV. BioRxiv.

Hall, Peter and Flandre, Thierry and Piaia, Alessandro and Colman, Karyn and Tarnow, Inge and Price, Mark and Haworth, Richard and Vahle, John and Cary, Maurice and Jones, David and Cauvin, Annick (2021) BSTP Review of 12 Case Studies Discussing the Challenges, Pathology, Immunogenicity, and Mechanisms of Inhaled Biologics. Experimental and Toxicologic Pathology. ISSN 0192-62331533-1601

Hall, Peter and Vahle, John and Colman, Karyn (2021) Inspiration and Exasperation: The Challenges of Inhaled Biologics. Toxicologic Pathology. ISSN 15331601

Harlacher, Cornelius and Galli, Bruno and Meinel, Lorenz and Schlauersbach, Jonas and Hanio, Simon and Lenz, Bettina and Vemulapalli, Sahithya and Griesinger, Christian and Pöppler, Ann-Christin (2021) Leveraging bile solubilization of poorly water-soluble drugs by rational polymer selection. Journal of Controlled Release, 330. pp. 36-48. ISSN 18734995

Hauptmann, Astrid and Hoelzl, Georg and Loerting, Thomas (2021) Optical cryomicroscopy and differential scanning calorimetry of buffer solutions containing cryoprotectants. European Journal of Pharmaceutics and Biopharmaceutics, Volume. pp. 127-140. ISSN 09396411

Heusser, Carolyn and Garad, Sudhakar and Sanchez-Felix, Manuel and Ganish, Ahil (2021) Patient-centric design for systemic peptide delivery: Trends in routes of administration and advancement in drug delivery technologies. Medicine in Drug Discovery.

Heymsfield, Steven and Coleman, Laura and Miller, Ram and Rooks, Daniel and Laurent, Didier and Petricoul, Olivier and Praestgaard, Jens and Swan, Therese and Wade, Thomas and Perry, Robert and Goodpaster, Bret and Roubenoff, Ronenn (2021) Bimagrumab, an Activin Type II Receptor Antagonist, for the Treatment of Obesity and Type 2 Diabetes: A Randomized ClinicalTrial. Journal of the American Medical Association.

Hinterholzer, Arthur and Stanojlovic, Vesna and Huber, Christian and Cabrele, Chiara and Schubert, Mario (2021) Detecting aspartate isomerization and backbone cleavage after aspartate in intact proteins by NMR spectroscopy. Journal of Biomolecular NMR, 75 (1). pp. 71-82. ISSN 15735001

Huth, Felix and Domange, Norbert and Poller, Birk and Vapurcuyan, Natasha and Durrwell, Alexandre and Hanna, Imad and Faller, Bernard (2021) Predicting Oral Absorption for Compounds Outside the Rule of Five Property Space. Journal of pharmaceutical sciences, 110 (6). pp. 2562-2569. ISSN 00223549

I

Israel, Laura and Glueck, Anton and Berger, Marjorie and Coral, Marine and Ceci, Melanie and Unterreiner, Adeline and Rubert, Joelle and Bardet, Maureen and Ginster, Stefanie and Ochsenbein, Alexandra and Martin, Kea and Hoyler, Thomas and Calzascia, Thomas and Wieczorek, Grazyna and Hillenbrand, Rainer and Ferretti, Stephane Raymond and Ferrero, Enrico and Bornancin, Frederic (2021) CARD10 cleavage by MALT1 restricts lung carcinoma growth in vivo. Oncogenesis, 6 (10 (4)). p. 32. ISSN 2157-9024

Iurlaro, Mario and Galli, Giorgio and Jagani, Zainab and Stadler, Michael and Schuebeler, Dirk (2021) Mammalian SWI/SNF continuously restores local accessibility to chromatin. Nature Genetics. ISSN 15461718

Iurlaro, Mario and Stadler, Michael and Galli, Giorgio and Jagani, Zainab and Schuebeler, Dirk (2021) Mammalian SWI/SNF continuously restores local accessibility to chromatin. Nature Genetics. ISSN 15461718

J

Johansson, David and Rauld, Celine and Roux, Julien and Regairaz Kalenga Kapiamba, Camille and Galli, Edoardo and Callegari, Ilaria and Raad, Layla and Waldt, Annick and Cuttat-Theurillat, Rachel and Roma, Guglielmo and Diebold, Martin and Becher, Burkhard and Kuhle, Jens and Derfuss, Tobias and Carballido, Jose and Sanderson, Nicholas (2021) Mass Cytometry of CSF Identifies an MS-Associated B-cell Population. Neurology(R) neuroimmunology & neuroinflammation, 8 (2). ISSN 23327812

Jordaan, Pierre and Abi-Gerges, Najah and Dumotier, Berengere and Ghetti, Andrea and Urban, Laszlo and Miler, Paul (2021) Cardiotoxic Potential of Hydroxychloroquine, Chloroquine and Azithromycin in adult Human Primary Cardiomyocytes. Toxicological Sciences, e-pub (e-pub). pp. 1-13. ISSN 1096-60801096-0929

K

Keller, Steve and Quiroz, Jorge and Christopher, Dave and Wickremsinhe, Enaksha and Geng, Wanping and Hawthorne, Glen and James, Christopher and Katterle, Yvonne and Li, Wenkui and Liu, Guowen and Mayer, Andrew and Paton, Martin and Pav, Joseph and Potter, Julian and Vergis, James and Wang, Jonathan (2021) The effectiveness of quality control samples in pharmaceutical bioanalysis. Bioanalysis, 13 (3). pp. 135-145. ISSN 17576199

Kingsley, Laura and He, Xiaohui and McNeill, Matthew and Nelson, John and Nikulin, Victor and Ma, Zhiwei and Lu, Wenshuo and Zhou, Vicki and Manuia, Mari and Kreusch, Andreas and Gao, Mu-Yun and Witmer, Darbi and Vaillancourt, Mei Ting and Lu, Min and Greenblatt, Sarah and Lee, Christian and Bender, Steven and Spraggon, Glen and Michellys, Pierre and Jia, Yong and Haling, Jake and Lelais, Gerald (2021) Structure-based design of selective LONP1 inhibitors for probing in vitro biology. Journal of Medicinal Chemistry. ISSN 0022-26231520-4804

Kleinbeck-Riniker, Florian and Schlama, Thierry and Ruch, Thomas and Novick, Scott and Dellas, Nikki and Garcia, Ravi and Ching, Charlene and Bautista, Abby and Homan, David and Alvizo, Oscar and Entwistle, David (2021) Engineering an omega-Transaminase for the Efficient Production of a Chiral Sacubitril Precursor. ACS Catalysis, 11. pp. 3762-3770. ISSN 2155-54352155-5435

Kleinbeck-Riniker, Florian and Schlama, Thierry and Ruch, Thomas and Novick, Scott and Dellas, Nikki and Garcia, Ravi and Ching, Charlene and Bautista, Abby and Homan, David and Alvizo, Oscar and Entwistle, David (2021) Engineering an omega-Transaminase for the Efficient Production of a Chiral Sacubitril Precursor. ACS Catalysis, 11. pp. 3762-3770. ISSN 2155-54352155-5435

Krantz, Carsten (2021) Review of the Technical, Toxicological, and PKPD Considerations for Conducting Inhalation Toxicity Studies on Biologic Pharmaceuticals—The Outcome of a Cross-Industry Working Group Survey. Toxicologic Pathology. ISSN 15331601

Krell, Christoph and Gallou, Fabrice (2021) Water waste from surfactant chemistry: risk or opportunity? Organic process research & development, 25.

L

Lapointe, Guillaume and Skepper, Colin and Holder, Lauren and Armstrong, Duncan and Bellamacina, Cornelia and Blais, Johanne and Bussiere, Dirksen and Bian, Jianwei and Cepura, Cody and Chan, Helen and Dean, Charles and De Pascale, Gianfranco and Dhumale , Bhavesh and Fisher, L. Mark and Fulsundar , Mangesh and Kantariya, Bhavin and Kim, Julie and King, Sean and Kossy, Lauren and Kulkarni, Upendra and Lakshman, Jay and Leeds, Jennifer and Ling, Xiaolan and Lvov, Anatoli and Ma, Sylvia and Malekar, Swapnil and Mckenney, David and Mergo, Wosenu and Metzger Iv, Louis and Mhaske, Keshav and Moser, Heinz and Mostafavi, Mina and Namballa, Sunil and Noeske, Jonas and Osborne, Colin and Patel, Ashish and Patel, Darshit and Patel, Tushar and Piechon, Philippe and Polyakov, Valery and Prajapati, Kruna and Prosen, Katie and Reck, Folkert and Richie, Daryl and Sanderson, Mark and Satasia, Shailesh and Savani, Bhautik and Selvarajah, Jogitha and Sethuraman, Vijay and Shu, Wei and Tashiro, Kyuto and Thompson, Katherine and Vaarla, Krishniah and Vala, Lakhan and Veselkov, Dennis and Vo, Jason and Vora, Bhavesh and Wagner, Beatrix and Wedel, Laura and Williams, Sarah and Yendluri, Satya and Yue, Qin and Yifru, Aregahegn and Zhang, Yong and Rivkin, Alexey (2021) Discovery and Optimization of DNA Gyrase and Topoisomerase IV Inhibitors with Potent Activity Against Fluoroquinolone-Resistant Gram-positive Bacteria. Journal of Medicinal Chemistry. ISSN 0022-26231520-4804

Lenz, Jan and Bunjes, Heike and Kwade, Arno and Juhnke, Michael (2021) An Improved Method for the Simultaneous Determination of Water Uptake and Swelling of Tablets. International journal of pharmaceutics, 595 (n/a). p. 120229. ISSN 1873-3476; 0378-5173

Lima, Fabio and Meisenbach, Mark and Schenkel, Berthold and Sedelmeier, Joerg Mathias (2021) Continuous Flow as an Enabling Technology: A Fast and Versatile Entry to Functionalized Glyoxal Derivatives. Organic & Biomolecular Chemistry. ISSN 1477-05201477-0539

Liu, Chen and Lu, Henry and Wang, Hongyun and Loo, Alice and Zhang, Xiamei and Yang, Guizhi and Kowal, Colleen and Delach, Scott and Wang, Ye and Goldoni, Silvia and Hastings, Bill and Wong , Karrie and Gao, Hui and Meyer, Matthew and Moody, Susan and LaMarche, Matthew and Engelman, Jeffrey and Williams, Juliet and Hammerman, Peter and Abrams, Tinya and Mohseni, Morvarid and Caponigro, Giordano and Hao, Huaixiang (2021) Combinations with allosteric SHP2 inhibitor TNO155 to block receptor tyrosine kinase signaling. Clinical Cancer Research, 27 (1). pp. 342-354. ISSN 15573265

Lopez, John and G. de la Torre1, Beatriz and Albericio, Fernando and Ramkisson, Shaveer (2021) Refractive Index: The Ultimate Tool for Real-Time Monitoring of Solid-Phase Peptide Synthesis. Greening the Process. Organic Process Research & Development, 25 (https:). pp. 1047-1053. ISSN 1520-586X.

Luo, Mai and Spradlin, Jessica and Boike, Lydia and Tong, Bingqi and Brittain, Scott and McKenna, Jeffrey and Tallarico, John and Schirle, Markus and Maimone, Thomas and Nomura, Dan (2021) Chemoproteomics-Enabled Ligand Screening Yields Covalent RNF114-Based Degraders that Mimics Natural Product Function. Cell chemical biology. ISSN 24519456

M

Marc, Philippe (2021) Data Science in R&D: it is about culture! Pharma Tech Outlook.

Markert, Christian and Thoma, Gebhard and Srinivas, Honnappa and Bollbuck, Birgit and Lueoend, Rainer Martin and Miltz, Wolfgang and Waelchli, Rudolf and Wolf, Romain and Hinrichs, Juergen and Bergsdorf, Christian and Azzaoui, Kamal and Penno, Carlos and Klein, Kai and Wack, Nathalie and Jaeger, Petra and Hasler, Franziska and Beerli, Christian and Loetscher, Pius and Dawson King, Janet and Wieczorek, Grazyna and Numao, Shin and Littlewood-Evans, Amanda and Roehn, Till (2021) Discovery of LYS006, a Potent and Highly Selective Inhibitor of Leukotriene A4 Hydrolase. Journal of medicinal chemistry.

Martin, Eric and Bosc, Nicolas and Felix, Eloy and Saunders, Martin R. and Green, Darren V. S. and Ochoada, Jason and Shelat, Anang A. and Iyer, Preeti and Engkvist, Ola and Verras, Andreas and Duffy, James and Gardner, J. Mark. F. and Leach, Andrew R. (2021) MAIP: A prediction platform for predicting blood-stage malaria inhibitors. Journal of Cheminformatics , 13 (1). p. 13. ISSN 1758-2946

Martin, Eric and Zhu, Xiangwei (2021) Collaborative Profile-QSAR: A Natural Platform for Building Collaborative Models among Competing Companies. Journal of chemical information and modeling, 61 (4). pp. 1603-1616. ISSN 1549960X

Martus, Hans-Joerg and Erkman, Linda and Maremanda, Nihal and Elhajouji, Azeddine and Hartmann, Andreas (2021) Comprehensive review of genotoxicity data for diclofenac. Mutation research..

Maziarz, Krzysztof and Jackson-Flux, Henry and Cameron, Pashmina and Sirockin, Finton and Schneider, Nadine and Stiefl, Nikolaus and Brockschmidt, Marc (2021) Learning to Extend Molecular Scaffolds with Structural Motifs. International Conference on Machine Learning.

McIntosh, Avery and Sverdlov, Alex and Yu, Li and Kaufmann, Petra (2021) Clinical design and analysis strategies for development of cell and gene therapies: quantitative drug development in the age of genetic medicine. Clinical pharmacology and therapeutics. pp. 1-9.

Meyer, Robina M. and Berger, Lukas and Nerkamp, Joerg and Scheler, Stefan and Nehring, Sebastian and Friess, Wolfgang (2021) Identification of Monoclonal Antibody Variants Involved in Aggregate Formation - Part 1: Charge Variants. European journal of pharmaceutics and biopharmaceutics, 158. pp. 123-131. ISSN 1873-3441

Meyer., Robina M. and Berger, Lukas and Nerkamp, Joerg and Scheler, Stefan and Nehring, Sebastian and Friess, Wolfgang (2021) Identification of monoclonal antibody variants involved in aggregate formation – Part 2: Hydrophobicity variants. European Journal of Pharmaceutics and Biopharmaceutics, 160 (March ). pp. 134-142. ISSN 18733441

N

Nauwelaerts, Nina and Deferm, Neel and Smits, Anne and Bernardini, Chiara and Lammens, Bart and Gandia, Peggy and Panchaud, Alice and Nordeng, Hedvig and Bacci, Maria Laura and Forni, Monica and Ventrella, Domenico and Van Calsteren, Kristel and DeLise, Anthony and Huys, Isabelle and Bouisset-Leonard, Michele and Allegaert, Karel and Annaert, Pieter (2021) A comprehensive review on non-clinical methods to study transfer of medication into breast milk – A contribution from the ConcePTION project. Biomedicine and Pharmacotherapy, 136. p. 111038. ISSN 19506007

P

Parmentier, Michael and Li, Wei and Dalton, Charlotte and Diorazio, Louis and Doerfler, Jaika and Engl, Olivier and Han, Zhengxu and Howell, Gareth and Hutchby, Marc and Latham, Jonathan and McLaws, Mark and Munday, Rachel and Navarro, Antonio and Pawlas, Jan and Roiban, Doru and Terrett, Jack and Treitler, Daniel and Zeng, Mingshuo and Steven, Alan (2021) Green Chemistry Articles of Interest to the Pharmaceutical Industry. Organic Process Research & Development. ISSN 1083-61601520-586X

Pikman, Yana and Tasian, Sarah K and Sulis, Maria Luisa and Stevenson, Kristen and Blonquist, Traci M and Apsel Winger, Beth and Cooper, Todd M and Pauly, Melinda and Maloney, Kelly W and Burke, Michael J and Brown, Patrick A and Gossai, Nathan and McNeer, Jennifer L and Shukla, Neerav N and Cole, Peter D and Kahn, Justine M and Chen, Jing and Barth, Matthew J and Magee, Jeffrey A and Gennarini, Lisa and Adhav, Asmani A and Clinton, Catherine M and Ocasio-Martinez, Nicole and Gotti, Giacomo and Li, Yuting and Lin, Shan and Imamovic, Alma and Tognon, Cristina E and Patel, Tasleema and Faust, Haley L and Contreras, Cristina F and Cremer, Anjali and Cortopassi, Wilian A and Garrido Ruiz, Diego and Jacobson, Matthew P and Dharia, Neekesh V and Su, Angela and Robichaud, Amanda L and Saur Conway, Amy and Tarlock, Katherine and Stieglitz, Elliot and Place, Andrew E and Puissant, Alexandre and Hunger, Stephen P and Kim, Annette S and Lindeman, Neal I and Gore, Lia and Janeway, Katherine A and Silverman, Lewis B and Tyner, Jeffrey W and Harris, Marian H and Loh, Mignon L and Stegmaier, Kimberly (2021) Matched Targeted Therapy for Pediatric Patients with Relapsed, Refractory or High-risk Leukemias: A Report from the LEAP Consortium. Cancer discovery. ISSN 2159-8290

Pistorius, Dominik and Buntin, Kathrin and Weber, Eric and Richard, Etienne and Bouquet, Caroline and Wollbrett, Severine (2021) Genetic engineering of Chromobacterium vaccinii DSM 25150 for improved production of FR900359. ChemRxiv (https://chemrxiv.org/).

Prabhath , Anupama and Vernekar , Varadraj N and Vasu , Vignesh and Badon, Mary and Avochinou , Jean-Emmanuel and Asandei , Alexandru D and Kumbar , Sangamesh G and Weber, Eckhard and Laurencin , Cato T (2021) In Vitro Kinetic Degradation and In Vivo Biocompatibility Evaluation of Polycaprolactone-Based Growth Factor Delivery Matrices in the Rotator Cuff. Journal of Biomedical Materials Research Part A. ISSN 1549-32961552-4965

R

Rago, Florencia and Rodrigues, Lindsey and Bonney, Megan and Sprouffske, Kathleen and Kurth, Esther and Elliott, GiNell and Ambrose, Jessi and Aspesi Jr, Peter and Oborski, Justin and Chen, Julie and McDonald III, Earl and Mapa, Felipa and Ruddy, David and Kauffmann, Audrey and Abrams, Tinya and Bhang, Hyo-eun and Jagani, Zainab (2021) Exquisite Sensitivity to Dual BRG1/BRM ATPase Inhibitors Reveals Broad SWI/SNF Dependencies in Acute Myeloid Leukemia. BioRxiv.

Risitano, Antonio and Röth, Alexander and Soret, Juliette and Frieri, Camilla and Sicre de Fontbrune, Flore and Marano, Luana and Alashkar, Ferras and Rozenberg, Izabela and Milojevic, Julie and End, Peter and Nidamarthy, Prasanna and Junge, Guido and Peffault de Latour, Regis (2021) Addition of iptacopan, an oral factor B inhibitor, to eculizumab in patients with paroxysmal nocturnal haemoglobinuria and active haemolysis: an open-label, single-arm, phase 2, proof-of-concept trial. The Lancet. Haematology. ISSN 2352-3026

Robbins, Jeremy M and Peterson, Bennet and Schranner, Daniela and Tahir, Usman A and Keyes, Michelle and Katz, Daniel and Jean Beltran, Pierre M and Barber, Jacob L and Baumgartner, Christian and Carr, Steven A and Ghosh, Sujoy and Jennings, Lori and Shen, Changyu and Sarzynski, Mark A and Bouchard, Claude and Gerszten , Robert E (2021) Human plasma proteomic profiles indicative of cardiorespiratory fitness. Nature Metabolism. ISSN 25225812

Robbins, Lindsey A. and Green-Miller, Angela R. and Johnson, Jay S. and Gaskill, Brianna N. (2021) One Is the Coldest Number: How Group Size and Body Weight Affect Thermal Preference in Weaned Pigs (3 to 15 kg). Animals, 11 (5). p. 1447. ISSN 2076-2615

Rueeger, Heinrich and Lueoend, Rainer Martin and Machauer, Rainer and Veenstra, Siem and Holzer, Philipp and Hurth, Konstanze and Voegtle, Markus and Frederiksen, Mathias and Rondeau, Jean-Michel and Tintelnot-Blomley, Marina and Jacobson, Laura and Staufenbiel, Matthias and Laue, Grit and Neumann, Ulf (2021) Synthesis of the Potent, Selective, and Efficacious β-Secretase (BACE1) Inhibitor NB-360. Journal of Medicinal Chemistry, 64 (8). pp. 4677-4696. ISSN 0022-26231520-4804

S

SEBASTIANI, PAOLA and MONTI, STEFANO and FEDERICO, ANTHONY and Morris, Melody and GURINOVICH, ANASTASIA and TOSHIKO, TANAKA and BHUTKAR, APARNA and ANDERSON, STACY L and FERRUCCI, LUIGI and Glass, David and Jennings, Lori and PERLS, THOMAS T (2021) Protein signatures of centenarians and their offspring suggest centenarians age slower than other humans. Aging Cell. ISSN 14749726

Santandrea, Ernesto and Waldraff, Christine and Gerber, Gilles and Moreau, Mael and Beney, Pascal (2021) Development of the late-phase manufacturing process to ZPL389: control of process impurities by enhanced process knowledge. Organic process research & development.

Schmelzer, Bernhard and Mischo, André and Innerbichler, Franz (2021) Statistically significant versus practically relevant trend in stability data. PDA journal of pharmaceutical science and technology. ISSN 19482124

Schuhmacher, Alexander and Wilisch, Lukas and Kandelbauer, Andreas and Hinder, Markus and Gassmann, Oliver (2021) R&D efficiency of leading pharmaceutical companies - a 20-year analysis. Drug Discovery Today, 2021 M (S1359-). pp. 36-41.

Schuhmacher, Alexander and Wilisch, Lukas and Kandelbauer, Andreas and Hinder, Markus and Gassmann, Oliver (2021) R&D efficiency of leading pharmaceutical companies — a 20-year analysis. Drug discovery today, May 20.

Schutten, Melissa and Knoblaugh, Sue and Salas , Elisa and Edmondson, Elijah and Cossic, Brieuc and Everitt, Jeffrey and Saravanan, Chandrassegar and Schmidt, Sarah and Schumacher, Vanessa and Zimmerman, Kurt (2021) Letter to the Editor Regarding “Pathology Informatics Education Committee of the American College of Veterinary Pathologists (ACVP)”. Toxicologic pathology, 49 (4). pp. 709-710. ISSN 1533-1601; 0192-6233

Schutzius, Gabi and Hauer, Christian and Bergling, Sebastian and Tortelli, Federico and Fuchs, Florian and Renner, Steffen and Guagnano, Vito and Cotesta, Simona and Rueeger, Heinrich and Faller, Michael and Bouchez, Laure and Salathe, Adrian and Nigsch, Florian and Richards, Shola and Louis, Malvina Caroline and Gruber, Viktoria and Aebi, Alexandra and Turner, Jonathan and Grandjean, Frederic and Li, Jun and Dimitri, Christopher and Thomas, Jason and Schirle, Markus and Blank, Jutta and Drueckes, Peter and Vaupel, Andrea and Tiedt, Ralph and Manley, Paul and Klopp, Julia and Hemmig, Rene and Zink, Florence and Leroy, Nelly and Carbone, Walter and Roma, Guglielmo and Gubser Keller, Caroline and Dales, Natalie and Beyerbach, Armin and Zimmerlin, Alfred Gilbert and Bonenfant, Debora and Terranova, Remi and Berwick, Amy and Sahambi, Sukhdeep and Reynolds, Aimee and Jennings, Lori and Ruffner, Heinz and Tarsa, Peter and Bouwmeester, Antonius and Driver, Vickie and Frederiksen, Mathias and Lohmann, Felix and Kirkland, Susan (2021) BET bromodomain inhibitors regulate keratinocyte plasticity. Nature Chemical Biology, 17 (3). pp. 280-290. ISSN 15524469

Sedlmayer, Ferdinand and Woischnig, Anne-Kathrin and Unterreiner, Vincent and Fuchs, Florian and Baeschlin, Daniel and Khanna, Nina and Fussenegger, Martin (2021) 5-Fluorouracil blocks quorum-sensing of biofilm-embedded methicillin-resistant Staphylococcus aureus in mice. Nucleic Acids Research. ISSN 0305-10481362-4962

Singh, Ashish Kumar and Schauer, Tamas and Pfaller, Lena and Straub, Tobias and Mueller-Planitz, Felix (2021) The biogenesis and function of nucleosome arrays. bioRxiv.

Stančič, Metka and Cvijic, Tamara and Kuzman, Drago and Mravljak, Rok and Gunčar, Gregor and Podgornik, Aleš (2021) Application of lectin immobilized on polyHIPE monoliths for bioprocess monitoring of Fc-fusion surface glycosylated protein. Journal of chromatography B : biomedical sciences and applications.

Streffer, Johannes and Treyer, Valerie and Buck, Alfred and Ametamey, Simon and Blagoev, Milen and Schmidt, Mark and Gautier, Aurelie and Maguire, Paul and Auberson, Yves and Vranesic, Ivan-Toma and Gomez-Mancilla, Baltazar and Gasparini, Fabrizio (2021) Regional brain mGluR5 receptor occupancy following single oral doses of mavoglurant as measured by [11C]-ABP688 PET imaging in healthy volunteers. NeuroImage, 230. ISSN 10538119

Streubel-Gallasch, L and Giusti, V and Sandre, M and Tessari, I and Plotegher, N and Giusto, E and Masato, A and Iovino, L and Battisti, I and Arrigoni, G and Shimshek, Derya and Greggio, E and Tremblay, ME and Bubacco, L and Erlandsson, A and Civiero, L (2021) Parkinson’s Disease–Associated LRRK2 Interferes with Astrocyte-Mediated Alpha-Synuclein Clearance. Molecular Neurobiology. ISSN 15591182

Sukseree, Supawadee and Bakiri, Latifa and Paloma-Irigoyen, Marta and Uluckan, Ozge and Petzelbauer, Peter and Wagner, Erwin (2021) Sequestosome 1/p62 enhances chronic skin inflammation. The Journal of allergy and clinical immunology. ISSN 10976825

T

To, Jeremy and Quackenbush, Doug and Rowell, Emily and Li, Lilin and Lo, Frederick and Horman, Shane (2021) A biomimetic assay platform for the interrogation of antigen-dependent anti-tumor T-cell function. Communications biology, 4. p. 56. ISSN 2399-3642

Tsai, Wan-Chen and Aleem, Ansari Mukhtar and Whittington, Chris and Cortopassi, Wilian A. and Kalyanaraman, Chakrapani and Baroz, Angel and Iavarone, Anthony T. and Skrzypczak-Jankun, Ewa and Jacobson, Matthew P. and Offenbacher, Adam R. and Holman, Theodore (2021) Mutagenesis, Hydrogen–Deuterium Exchange, and Molecular Docking Investigations Establish the Dimeric Interface of Human Platelet-Type 12-Lipoxygenase. Biochemistry, 60 (10). pp. 802-812. ISSN 0006-2960

Turner, Oliver and Rudmann, Daniel and Knight, Brian and Zuraw, Aleksandra and Litjens, Geert (2021) Mini Review: The Last Mile—Opportunities and Challenges for Machine Learning in Digital Toxicologic Pathology. Toxicologic pathology.

U

Unterreiner, Adeline and Rubert, Joelle and Kauffmann, Muriel and Fruhauf, Alice and Heiser, Diane and Erbel, Paulus and Schlapbach, Achim and Eder, Joerg and Bodendorf, Ursula and Boettcher, Andreas and Farady, Christopher and Bornancin, Frederic (2021) Pharmacological inhibition of IKKβ dampens NLRP3 inflammasome activation after priming in the human myeloid cell line THP-1. Biochemical and biophysical research communications : BBRC, 545. pp. 177-182. ISSN 0006291X

V

Velasco-Estevez, M and Koch, N and Klejbor, I and Laurent, Stephane and Dev, K and Szutowicz, A and Sailer, Andreas and Rutkowska, A (2021) Ebi2 is temporarily upregulated in mo3.13 oligodendrocytes during maturation and regulates remyelination in the organotypic cerebellar slice model. International Journal of Molecular Sciences, 22 (9). ISSN 14220067

Ventrella, Domenico and Ashkenazi, Nurit and Elmi, Alberto and Allegaert, Karel and Aniballi, Camilla and DeLise, Anthony and Devine, PJ and Smits, Anne and Steiner, Lilach and Forni, Monica and Bouisset-Leonard, Michele and Bacci, Maria Laura (2021) Animal models for in vivo lactation studies: anatomy, physiology and milk compositions in the most used non-clinical species, a contribution from the ConcePTION project. Animals, 11 (3). pp. 714-733. ISSN 2076-2615

Vidal, Justin and Colman, Karyn and Bhaskaran, Manoj and de Rijk, Eveline and Fegley, Darren and Haplern, Wendy and Jacob, Binod and Kandori, Hitoshi and Manickam, Balasubramanian and McKeag, Sean and Parker, George A. and Regan, Karen S. and Sefing, Benjamin and Thibodeau, Michael and Vemireddi, Vimala and Werner, Jonathan and Zalewska, Aleksandra (2021) Scientific and Regulatory Policy Committee Best Practices*: Documentation of Sexual Maturity by Microscopic Evaluation in Nonclinical Safety Studies. Toxicologic Pathology. ISSN 15331601

Vittal, Shivva and Fink, Martin and Lowe, Philip J (2021) Improving priors for human monoclonal antibody linear pharmacokinetic parameters by using half-lives from non-human primates. Journal of Pharmacokinetics and Pharmacodynamics. ISSN 15738744

van Hoogevest, Peter and Tiemessen, Harry and Metselaar, Josbert and Fahr, Alfred (2021) The Use of Phospholipids to make Pharmaceutical Form Line Extensions. European Journal of Lipid Science and Technology. ISSN 1438-76971438-9312

W

Walker, Keenan A. and Chen, Jingsha and Zhang, Jingning and Fornage, Myriam and Tin, Adrienne and Daya, Natalie and Hoogeveen, Ron C and Wu, Aozhou and Sullivan, Kevin J and Ganz, Peter and Zeger, Scott L and Yang, Yunju and Gudmundsson, Elias F and Emilsson, Valur and Launer, Lenore J and Jennings, Lori and Gudnason, Vilmundur and Chatterjee, Nilanjan and Gottesman, Rebecca F and Mosley, Thomas H and Boerwinkle, Eric and Ballantyne, Christie M and Coresh, Josef and Zhou, Linda and Grams, Morgan E (2021) Large-scale plasma proteomic analysis identifies proteins and pathways associated with dementia risk. Nature Aging.

Wang, Xinting and Bartels, Christian and Kulkarni, Swarupa and Sangana, Ramachandra and Jain, Monish and Zack, Julia and Yu, Jing (2021) Population Pharmacokinetic Analysis of Fevipiprant in Healthy Subjects and Asthma Patients using a Tukey's g-and-h Distribution. Drug Research. ISSN 21949387

Wang-Lakshman, Lydia and Mendonza, Anisha and Huber, Roland and Walles, Markus and He, Yan-Ling and Jarugula, Venkateswar (2021) Pharmacokinetics, Metabolism, and Excretion of Licogliflozin, a Dual Inhibitor of SGLT1/2, in Rats, Dogs, and Humans. Xenobiotica.

Weiss, Markus and Cain, Meredith and Langenickel, Thomas and Kulkarni, Swarupa and Shah, Bharti and Rahmanzadeh, Gholamreza and Poller, Birk and Vemula, Janardhana Rao (2021) Clinical investigation of metabolic and renal clearance pathways contributing to the elimination of fevipiprant using probenecid as perpetrator. Drug metabolism and disposition, 49 (5). pp. 389-394. ISSN 1521-009X

Woicke, Jochen and Al-Haddawi, Muthafar M and Bienvenu, Jean-Guy and Caverley Rae, Jessica M and Chanut, Franck J and Colman, Karyn and Cullen, John and Davis, Wendell and Fukuda, Ryo and Huisinga, Maike and Junker Walker, Ursula and Kai, Kiyonori and Kovi, Ramesh C and Macri, Nicholas P and Marxfeld, Heike-Antje and Nikula, Kristin J and Pardo, Ingrid D and Rosol, Thomas J and Sharma, Alok K and Singh, Bhanu P and Tamura, Kazutoshi and Thibodeau, Michael S and Vezzali, Enrico and Vidal, Justin D and Meseck, Emily (2021) International Harmonization of Nomenclature and Diagnostic Criteria (INHAND): Nonproliferative and Proliferative Lesions of the Dog. Toxicologic Pathology, 49 (1). pp. 5-109. ISSN 15331601

Wuensch, Isabell and Finke, Jan and John, Edgar and Juhnke, Michael and Kwade, Arno (2021) The influence of particle size on the application of compression and compaction models for tableting. International journal of pharmaceutics, 599 (n/a). 120424-n/a. ISSN 0378-5173

Wünsch, Isabell and Michel, Stephanie and Finke, Jan Henrik and John, Edgar and Juhnke, Michael and Kwade, Arno (2021) How can single particle compression and nanoindentation contribute to the understanding of pharmaceutical powder compression? European Journal of Pharmaceutics and Biopharmaceutics, 165 (n/a). pp. 203-218. ISSN 0939-6411

Z

Zhang, Zhe (2021) Solving Complex Biologics Truncation Problems by Top-Down Mass Spectrometry. Journal of the American Society for Mass Spectrometry. ISSN 1879-1123; 1044-0305

Zhou, Lili and Miller, Caitlyn and Miraglia, Loren and Mendiola, Angelica and Mure, Ludovic S. and Panda, Satchidananda and Xiao, Changchun and Kay, Steve (2021) A genome-wide microRNA screen identifies the microRNA-183/96/182 cluster as a modulator of circadian rhythms. Proceedings of the National Academy of Sciences, 118 (1). ISSN 0027-84241091-6490

This list was generated on Mon Jun 21 03:36:24 2021 UTC.

Search

Email Alerts

Register with OAK to receive email alerts for saved searches.