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Number of items: 207.


Aeffner, Famke and Turner, Oliver and Sing, Tobias (2021) Special Issue on Digital Pathology, Tissue Image Analysis, Artificial Intelligence, and Machine Learning: Approximation of the Effect of Novel Technologies on Toxicologic Pathology. Toxicologic Pathology, Volume (4). pp. 705-708. ISSN 15331601

Aksenov, Sergey and Roberts, John and Ganesh, Mugundu and Thudium-Mueller, Karen and Bhattacharya, Indranil and Tortorici, Michael (2021) Rational prediction of human dose for gene therapy based on translational dose-response studies. Clinical Pharmacology & Therapeutics. ISSN 0009-92361532-6535

Albanese, F and Mercatelli, D and Finetti, L and Lamonaca, G and Pizzi, S and Shimshek, Derya and Bernacchia, G and Morari, M (2021) Constitutive silencing of LRRK2 kinase activity leads to early glucocerebrosidase deregulation and late impairment of autophagy in vivo. Neurobiology of Disease, 159. ISSN 1095953X

Anderka, Oliver and Graf, Tobias and Seisenberger, Christina and Wiedmann, Michael and Wohlrab, Stefanie (2021) Best practices on critical reagent characterization, qualification, and life cycle management for HCP immunoassays. Biotechnology and Bioengineering. ISSN 0006-35921097-0290

Auberson, Yves (2021) Reflections on 2018-2020. EFMC Yearbook, 2021. pp. 3-4.

Auld, Douglas and Jenkins, Jeremy and Concannon, John (2021) Cell size homeostasis is maintained by a circuitry involving a CDK4-determined target size that programs the cell size-dependent activation of p38. Developmental cell. ISSN 1878-1551

Axford, Jake and Briner, Karin and Cheung, Atwood and Dales, Natalie and Hurley, Timothy and Jain, Monish and Sung, Moo and Manchester, John and Hamann, Lawrence and Chin, Donovan and Shin, Youngah and Sivasankaran, Rajeev (2021) Use of Intramolecular 1,5-sulfur-oxygen and 1,5-sulfur-halogen interactions in the design of N-methyl-5-aryl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine SMN2 splicing modulators. Journal of Medicinal Chemistry. ISSN 0022-26231520-4804


Baczyk, Paulina and Wyss, Brigitte and Widmer, Jasmin and Hartmann, Steffen and Wassmann, Paul and Lobo, Susana and Jesus, Lídia and Gomes, Joana and Batista, Ana (2021) Stability liabilities of biotherapeutic proteins: early assessment as mitigation strategy. Journal of pharmaceutical and biomedical analysis, 192. pp. 1-15. ISSN 1873-264X; 0731-7085

Barabas, Amanda J and Soini, Helena A and Novotny, Milos V and Williams, David R and Desmond, Jacob A and Lucas, Jeffrey R and Erasmus, Marisa A and Cheng, Heng-Wei and Gaskill, Brianna N (2021) Compounds from plantar foot sweat, nesting material, and urine show strain patterns associated with agonistic and affiliative behaviors in group housed male mice, Mus musculus. PloS one, 16 (5). e0251416. ISSN 1932-6203

Baran, Szczepan and Lim, Maria A. and Do, Johnny P. and Stolyar, Polina and Rabe, Mark D. and Schaevitz, Laura R. and Cadena, Samuel (2021) Digital biomarkers enable automated, longitudinal monitoring in a mouse model of aging. The journals of gerontology. Series A, Biological sciences and medical sciences. ISSN 1758535X

Bartels, Christian and Dumortier, Thomas (2021) Inverse probability of censoring weighting for visual predictive checks of time-to-event models with time-varying covariates. Pharmaceutical Statistics. ISSN 1539-16041539-1612

Bartels, Christian and Jain, Monish and Yu, Jing and Tillmann, Hanns-Christian and Vaidya, Soniya (2021) Population Pharmacokinetic Analysis of Indacaterol/Glycopyrronium/Mometasone Furoate After Administration of Combination Therapies Using the Breezhaler® Device in Patients with Asthma. European Journal of Drug Metabolism and Pharmacokinetics, 46 (4). pp. 487-504. ISSN 21070180

Barth, Melanie and Bacioglu, Mehtap and Tanriöver, Gaye and Schwarz, Niklas and Novotny, Renata and Brandes, Janine and Welzer, Marc and Mazzitelli, Sonia and Häsler, Lisa and Schweighauser, Manuel and Kronenberg-Versteeg, Deborah and Fog, Karina and Ambjørn, Malene and Bousset, Luc and Melki, Ronald and Shimshek, Derya and Koch, Henner and Jucker, Mathias (2021) Microglial inclusions and neurofilament light chain release follow neuronal α-synuclein lesions in long-term brain slice cultures. Molecular Neurodegeneration, 16 (1). ISSN 17501326

Bashkar, Varun and Desogus, Jessica and Graff-Meyer, Alexandra and Schenk, Andreas and Cavadini, Simone and Chao, Jeffrey A (2021) Dynamic association of human Ebp1 with the ribosome. RNA (New York, N.Y.), 27 (4). pp. 411-419. ISSN 1469-9001

Bednarczyk, Dallas (2021) Passive influx and ion trapping are more relevant to the cellular accumulation of highly permeable low molecular weight acidic drugs than is Organic Anion Transporter 2 (OAT2). Drug metabolism and disposition: the biological fate of chemicals. ISSN 1521009X

Begum, Alaybeyoglu and Ho Wa, Cheng and Kshama, Doshi and Vishruti, Makani and Stein, Andrew (2021) Estimating drug potency in the competitive target mediated drug disposition (TMDD) system when the endogenous ligand is included. Journal of Pharmacokinetics and Pharmacodynamics, 48 (4). pp. 447-464. ISSN 15738744

Bieberich, Andrew and Rajwa, Bartek and Irvine, Allison and Fatig, Raymond and Fekete, Alexander and Jin, Hong and Kutlina, Elena and Urban, Laszlo (2021) Acute Cell Stress Screen with Supervised Machine Learning in Association with in vitro Pharmacological Profiling Predicts Cytotoxicity of Excipients. Journal of Pharmacological and Toxicological Methods, e-pub. pp. 1-15.

Biering, Scott B. and Van Dis, Erik and Yamashiro, Livia H. and Nguyenla, Xammy and Wehri, Eddie and Dugast-Darzacq, Claire and Graham, Thomas G.W. and Stroumza, Julian and Golovkine, Guillaume and Roberts, Allison W. and Fines, Daniel M. and Fox, Douglas M. and Ward, Carl and Spradlin, Jessica and Dovala, Dustin and Schaletzky, Julia and Stanley, Sarah A. (2021) Screening a Library of FDA-Approved and Bioactive Compounds for Antiviral Activity against SARS-CoV-2. ACS infectious diseases. ISSN 23738227

Bleu, Melusine and Grass, Verena and Mermet-Meillon, Fanny Anne-Marie and Barys, Louise and Holzer, Laura and Marques Lopes, Rui and Barbosa, Ines and Delmas, Cecile and Hinniger, Alexandra and Chau, Suzanne and Kaufmann, Markus and Haenni, Simon and Berneiser, Karolin Fiona and Wahle, Maria and Moravec, Ivana and Vissieres, Alexandra and Poetsch, Tania and Ahrne, Erik and Carte, Nathalie and Voshol, Johannes and Fischer, Matteo and Stachyra, Therese-Marie and Freuler, Felix and Gutmann, Sascha and Fernandez, Cesar and Naumann, Ulrike and Roma, Guglielmo and Schuebeler, Dirk and Nieto-Oberhuber, Cristina and Cobos-Correa, Amanda and Ferretti, Stephane Raymond and Galli, Giorgio (2021) PAX8 and MECOM are interaction partners driving Ovarian Carcinogenesis. Nature communications, 12. p. 2442. ISSN 2041-1723

Boyle, Molly and Bennet, Bindu and Houle, Christopher D. and Sura, Radhakrishna and Colman, Karyn and Romeike, Annette and Frisk, Anna-Lena and Garcia, Begonya and Elmore, Susan A. (2021) Publication Categories in Toxicologic Pathology. Toxicologic Pathology. ISSN 15331601

Brase, Jan Christoph and Robert, Walter and Savchenko, Alexander and Gusenleitner, Daniel and Garrett, James and Schimming, Tobias and Varaljai, Renata and Castelletti, Deborah and Kim, Ju and Dakappagari, Naveen and Schultz Gonzaga, Kenneth and Robert, Caroline and Long, Georgina V and Nathan, Paul and Ribas, Antoni and Flaherty, Keith and Karaszewska, Boguslawa and Schachter, Jacob and Sucker, Antje and Schmid, Kurt W and Zimmer, Lisa and Livingstone, Elisabeth and Tan, Sartika and Schadendorf, Dirk and Roesch, Alexander (2021) Role of Tumor-Infiltrating B Cells in Clinical Outcome of Patients with Melanoma Treated With Dabrafenib Plus Trametinib. Clinical cancer research : an official journal of the American Association for Cancer Research. ISSN 15573265

Briggs, Katahrine and Camara, Tima and Diaz, Carlos and Drew, Phil and Drewe, Will and Kors, Jan and van Mulligen, Erik and Pognan, Francois and Quintana, Jordi Ramon and Sarntivijai, Sirarat and Steger-Hartmann, Thomas (2021) Guidelines for FAIR sharing of preclinical safety and off-target pharmacology data. ALTEX, 38 (2). pp. 187-197. ISSN 1868596X

Brightling, Christopher E and Kulkarni, Swarupa and Lambrecht, Bart and Sandham, David and Weiss, Markus and Altman, Pablo (2021) The pharmacology of the prostaglandin D2 receptor 2 (DP2) receptor antagonist, fevipiprant. Pulmonary Pharmacology and Therapeutics, 68. p. 102030. ISSN 15229629

Brogdon, Jennifer and Pruteanu-Malinici, Iulian and Melenhorst, J. Joseph and June, Carl H. and Fraietta, Joseph A. and Young, Regina M. and Levine, Bruce L. and Lacey, Simon F. (2021) Decade-long Remissions of Leukemia Sustained by the Persistence of Activated CD4 CAR T Cells. Science translational medicine.


Canham, Steve and Jenkins, Jeremy and Forrester, William and Hild, Marc and Ambrose, Jessi and Sigoillot, Frederic and Gleim, Scott and Cobos-Correa, Amanda and Wang, Ying and Eggimann, Fabian and Moore, Charles and Mapa, Felipa and Burks, Heather and Roma, Guglielmo and Krastel, Philipp and Tallarico, John and Nomura, Daniel and Fisher, David and Zhang, Lydia and Cho, Hyelim and Shen, Qiong and Okumura, Mikiko and Kawakami, Akinori and Miller, Howard and Dix, Ina and Ross, Nathan (2021) CYP27A1 dependent anti-melanoma activity of limonoid natural products targets mitochondrial metabolism. Cell chemical biology. ISSN 24519456

Carballido, Jose and Spits, Hergen (2021) Legends of allergy and immunology: Jan E. de Vries. Allergy. ISSN 13989995

Carbonneau, Seth and Sharma, Sujata and Peng, Liaomin and Rajan, Vaisakh and Hainzl, Dominik and Henault, Martin and Yang, Chian and Hale, Jacob and Shulok, Janine and Tallarico, John and Porter, Jeffrey and Brogdon, Jennifer and Dranoff, Glenn and Bradner, Jay and Hild, Marc and Guimaraes, Carla (2021) An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity. Cell Chemical Biology. ISSN 24519448

Cassaro, A and Grillo, G and Esposito, I and Reda, G and Cairoli, R and Beghini, A and Notaro, M and Gliozzo, J and Trojani, A and Valentini, G and Di Camillo, B (2021) FZD6 triggers Wnt–signalling driven by WNT10BIVS1 expression and highlights new targets in T cell acute lymphoblastic leukemia. Hematological oncology. ISSN 1099-1069

Chen, Heller and Cui, Xiaoming and Pognan, Nathalie and Quinlan, Michelle and Kapoor, Shruti and Rahmanzadeh, Gholamreza and Giovannini, Monica and Marbury, Thomas (2021) Pharmacokinetics of capmatinib in participants with hepatic impairment: A phase 1, open-label, single-dose, parallel-group study. British Journal of Clinical Pharmacology. ISSN 13652125

Chen, Wentao and Luo, Jian and Ye , Yuan and Hoyle, Ryan and Liu, Wei and Borst, Rowie and Kazani, Shamsah and Shikatani, Eric and Erpenbeck, Veit and Pavord, Ian and Klenerman, Paul and Sandham, David and xue, luzheng (2021) Prostaglandin D2 drives tissue remodelling functions and prostaglandin D2 autocrine production in type 2 cytotoxic T cells. The journal of immunology, 206. pp. 2714-2724. ISSN 1550-6606

Chen, Xinhui and Cui, Xiaoming and Pognan, Nathalie and Quinlan, Michelle and Kapoor, Shruti and Rahmanzadeh, Gholamreza and Giovannini, Monica and Marbury, Thomas C (2021) Pharmacokinetics of capmatinib in participants with hepatic impairment: A phase 1, open-label, single-dose, parallel-group study. British journal of clinical pharmacology. ISSN 1365-2125

Chiang, Chih-Yuan and Zhong, Yang and Ward, Michael M and Lane, Douglas J and Kenny, Tara and Rosario-Acevedo, Raysa and Eaton, Brett P and Trevino, Sylvia R and Chance, Taylor B and Worsham, Patricia L and Waag, David M and Moore, Richard T and Cazares, Lisa H and Cote , Christopher K and Zhou, Yingyao and Panchal, Rekha G (2021) Proteomic Analysis of Non-human Primate Peripheral Blood Mononuclear Cells During Burkholderia mallei Infection Reveals a Role of Ezrin in Glanders Pathogenesis. Frontiers in Microbiology, 12. ISSN 1664302X

Christler, Anna and Scharl, Theresa and Sauer, Dominik Georg and Koeppl, Johannes and Tscheließnig, Anne and Toy, Cabir and Melcher, Michael and Jungbauer, Alois and Dürauer, Astrid (2021) Technology transfer of a monitoring system to predict product concentration and purity of biopharmaceuticals in real‐time during chromatographic separation. Biotechnology and Bioengineering. pp. 1-12. ISSN 0006-3592

Christophe, Pellefigues and Karmella, Naidoo and Palak, Mehta and Alfonso , Schmidt and Ferdinand, Jagot and Roussel, Elsa and Cait, Alissa and Bibek, Yumnam and Sally, Chappell and Meijlink, Kimberly and Mali, Chamberis and Jean, Jiang and Gavin, Painter and Filbey, Kara and Uluckan, Ozge and Olivier, Gasser and Graham, LeGros (2021) Basophils promote barrier dysfunction and resolution in the atopic skin. Journal of Allergy and Clinical Immunology. ISSN 10976825

Cremer, Malika and Rooks, Daniel and Fretault, Nathalie and Schubert-Tennigkeit, Agnes Annette and Papanicolaou, Dimitris (2021) Bimagrumab to Improve Recovery after Hip Fracture in the Elderly: A Randomised, Double-Blind, Placebo-Controlled Phase 2a/b Study. The Lancet Healthy Longevity, 2 (5). E263-E274.


Dawson King, Janet and Vogelsanger, Melanie (2021) Cantharidin-induced skin blister as an in vivo model of inflammation. Current Protocols in Pharmacology , 1 (e49). pp. 1-14.

Diener, John and Mowbray, Sarah and Huang, WaanJeng and Yowe, David and Xu, Jian and Caplan, Shari and Misra, Abhay and Kapur, Ankur and Shapiro, Jeffrey and Ke, Xiaoling and Wu, Xiaoping and Bose, Avirup and Panza, Darrell and Chen, Min and Beaulieu, Valerie and Gao, Jiaping (2021) FGF21 Normalizes Plasma Glucose in Mouse Models of Type 1 Diabetes and Insulin Receptor Dysfunction. bioRxiv. pp. 1-19. ISSN

Dispas, Amandine and Guillarme, Davy and Hubert, Philippe and Clarke, Adrian and Grand-Guillaume-Perrenoud, Alexandre (2021) Interlaboratory study of a Supercritical Fluid Chromatography method for the determination of pharmaceutical impurities: evaluation of multi-systems reproducibility. Journal of pharmaceutical and biomedical analysis, 203 (Articl). ISSN 07317085

Dittrich, Birger (2021) On modelling disordered crystal structures through restraints from molecule-in-cluster computations,and distinguishing static and dynamic disorder. IUCrJ, International Union of Crystallography Journal , 8. pp. 305-318. ISSN 2052-2525

Dodd, Stephanie (2021) Use of PBPK Modeling for Predicting Drug-Food Interactions: Successful prediction using a middle-out approach. AAPS PharmSci, 23 (12). ISSN 1550-7416/21/0000-0001/0

Duca, Maria and Gillingham, Dennis and Olsen, Christian Adam and Sbardella, Gianluca and Skaanderup, Philip and van der Stelt, Mario and Vauzeilles, Boris and Vazquez, Ollala and Auberson, Yves (2021) The Chemical Biology-Medicinal Chemistry continuum: EFMC's vision. ChemBioChem, 22.


Elo, Petri and Li, Xiang-Guo and Liljenbäck, Heidi and Gardberg, Maria and Moisio, Olli and Miner, Maxwell and Virta, Jenni and Saraste, Antti and Srinivasarao, Madduri and Pugh, Michael and Low, Philip and Knuuti, Juhani and Jalkanen, Sirpa and Airas, Laura and Lu, June and Roivainen, Anne (2021) Efficacy and tolerability of a folic acid derivative of aminopterin in a rat focal model of multiple sclerosis. J Neuroinflammation, 18 (30).

Emmenegger, M and De Cecco, E and Hruska-Plochan, M and Eininger, T and Schneider, MM and Barth, M and Tantardini, E and de Rossi, P and Langston, RG and Kaga-novich, A and Gonzalez-Guerra, A and Avar, M and Heinzer, D and Reimann, R and Häsler, LM and Herling, TW and Matharu, NS and Landeck, N and Luk, K and Melki, R and Kahle, PJ and Hornemann, S and Knowles, TP and Cookson, MR and Polymenidou, M and Jucker, M and Aguzzi, A (2021) LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies. EMBO Molecular Medicine. ISSN 17574684

Emperador-Melero, Javier and Wong, Man Yan and Wang, Shan Shan H and de Nola, Giovanni and Nyitrai, Hajnalka and Kirchhausen, Tom and Kaeser, Pascal S (2021) PKC-phosphorylation of Liprin-α3 triggers phase separation and controls presynaptic active zone structure. Nature communications, 12 (1). p. 3057. ISSN 2041-1723

Evans, Tiffany R and Giridharan, Thejaswini and Singel, Kelly L and Khan, ANM Nazmul and Ricciuti, Jason and Howard, Kaitlyn and Silva-Del Toro, Stephanie L and Debreceni, Ivy L and Aarts, Cathelijn E. M. and Suzuki, Sora and Kuijpers, Taco W and Brouwer, Mieke C and Lee-Ann H, Allen and Viviana P, Ferreira and Schubart Wellensiek, Anna and Eder, Joerg and Holland, Steven M and Ram, Sanjay and Lederer, James A and Eng, Kevin H and Moysich, Kirsten B and Odunsi, Kunle and Yaffe, Michael B and Zsiros, Emese and Segal, Brahm H (2021) Mechanisms driving neutrophil-induced t-cell immunoparalysis in ovarian cancer. Cancer Immunology Research, 9 (7). pp. 790-810. ISSN 23266074

Even, Caroline and Li, Hung-Ming and Ngan, Roger and Dechaphunkul, Arunee and Zhang, Li and Jui Yen, Chia and Chan, Po Chung and Chakrabandhu, Somvilai and Ma, Brigette and Tanasanvimon, Suebpong and Lee, Victor and Lou, Pei-Jen and Li, Zujun and Spira, Alexander and Ammar , Sukari and Guigay, Joël and McCune, Steven and Lim, Darren Wan-Teck and Szpakowski, Sebastian and Yao, Yao and Liang, Coco and Mataraza, Jennifer and Sechaud, Romain and Manenti , Luigi (2021) Phase II, randomized study of spartalizumab (PDR001), an anti-PD-1 antibody, vs chemotherapy in patients with recurrent/metastatic nasopharyngeal cancer. Clinical cancer research. ISSN 1557-3265; 1078-0432

Evers, Felix and Cabrera-Orefice, Alfredo and Elurbe, Dei M and Kea-Te Lindert, Mariska and Niederwieser, Sylwia and Voss, Till S and Huynen, Martijn A and Brandt, Ulrich and Kooij, Taco W A (2021) Composition and stage dynamics of mitochondrial complexes in Plasmodium falciparum. Nature communications, 12 (1). p. 3820. ISSN 2041-1723


Fanale, Salvatore and Emmons, Kayla and Gunderson, Andrew (2021) WDII Unpacking and Startup Video. N/A, n/a (n/a). n/a-n/a. ISSN n/a

Fanous, Marina and Bitar, Malak and Gold, Sarah and Sobczuk, Adam and Hirsch, Stefan and Ogorka, Joerg and Imanidis, Georgios (2021) Immediate Release 3D-Printed Dosage Forms for Poorly Soluble Drugs: Development and Exploration of Morphology-Dissolution Relationship. International journal of pharmaceutics, 26. p. 120417. ISSN DOI: 10.1016/j.ijpharm.2021.120417

Filipponi, Paolo and Martin, Benjamin and Knochel, Paul and Heinz, Benjamin and Djukanovic, Dimitrije (2021) Regioselective Difunctionalization of Pyridines via 3,4-Pyridynes. Chemical Science, 12. pp. 6143-6147. ISSN

Frederiksen, Mathias (2021) The kinase chemogenomic set (KCGS): An open science resource for kinase vulnerability identification. International Journal of Molecular Sciences, 22 (2). pp. 1-18. ISSN 14220067

Freund, Ernst and Meyer, Daniel and Schneider, Nadine and Lozac'h, Marie-Anne and Schroeder, Harald and Cynar, Cagatay and Schlotterbeck, Goetz and Wagner, Beatrix (2021) Automated chiral method screening – Evaluation of generated chromatographic data sets to further optimize screening efficiency. Journal of Chromatography A, 1644. ISSN 0021-9673


Gallou, Fabrice (2021) Improved iGAL 2.0 Metric Empowers Pharmaceutical Scientists to Make Meaningful Contributions to U.N. Sustainable Development Goal 12. ACS Sustainable Chem. Eng.

Gallou, Fabrice (2021) La chimie verte comme catalyseur de l'innovation ! l'actualite chimique, 463. pp. 17-21.

Gallou, Fabrice (2021) Late-stage cyanation of aryl/heteroaryl halides using ppm levels of a bidentate phosphine-derived palladacycle in water. ChemCatChem., 13 (1). pp. 212-216. ISSN 1867-3899; 1867-3880

Gallou, Fabrice (2021) Mild and robust Stille reactions in water using ppm levels of a new triphenylphosphine-based palladacycle. Angewandte Chemie. International edition, 60 (9). pp. 4158-4163.

Gallou, Fabrice (2021) Nanochannels in Photoactive Cu(I) Polymer for Selective Oxidations in Aqueous Micelles. ACS Sustainable Chem. Eng, 9 (7). pp. 2854-2860.

Gallou, Fabrice (2021) Safe, Scalable, Inexpensive, and Mild Nickel-Catalyzed Migita-like C–S Cross-Couplings in Recyclable Water. Angewandte Chemie. International edition, 60 (7). pp. 3708-3713.

Gallou, Fabrice (2021) “TPG-lite”: A new, simplified “designer” surfactant for general use in synthesis under micellar catalysis conditions in recyclable water. Tetrahedron.

Gallou, Fabrice (2021) Visible Light mediated micellar one-pot Triazole formation. ChemSusChem, 14. pp. 2704-2710. ISSN 1864-564X; 1864-5631

Gallou, Fabrice (2021) Water in organic chemistry:from our worst enemy to our best friend. Chemical science, 12. pp. 4237-4266.

Gallou, Fabrice (2021) Water-Sculpting of a Heterogeneous Nanoparticle Pre-catalyst for Mizoroki-Heck Couplings Under Micellar Catalysis Conditions. Journal of the American Chemical Society JACS., 143 (9). pp. 3373-3382.

Gallou, Fabrice and Plummer, Scott (2021) Nanochannels in Photoactive Polymeric Cu(I) Compatible for Efficient Micellar Catalysis: Sustainable Aerobic Oxidations of Alcohols in Water. ACS Sustainable Chem. Eng., 9 (7). pp. 2854-2860.

Glowienke, Susanne (2021) Use of less-than-lifetime (LTL) durational limits for nitrosamines: Case study of N-Nitrosodiethylamine (NDEA). Regulatory Toxicology and Pharmacology, 123. ISSN 10960295

Goebel, Mathias and Dos Reis Rodrigues, Rui Claudio and Pampel, Lars and Rapp, Johanna and Shultz, Joseph and Cui, Huanchun (2021) Flow management strategies for a connected purification process. Biotechnology and bioengineering. ISSN 10970290

Golosov, Andrei and Flyer, Alec and Amin, Jakal and Babu, Charles and Gampe, Christian and Li, Jingzhou and Liu, Eugene and Nakajima, Katsumasa and Nettleton, David and Patel, Tej and Reid, Patrick and Yang, Lihua and Monovich, Lauren (2021) Design of thioether cyclic peptide scaffolds with passive permeability and oral exposure. Journal of medicinal chemistry, 64 (5). pp. 2622-2633.

Grass, Verena and Begue, Damien and Cordo, Valentina and Holzer, Laura and Martinuzzi-Duboc, Laetitia and Buhles, Alexandra and Kerr, Grainne and Barbosa, Ines and Naumann, Ulrike and Piquet, Michelle and Ruddy, David and Tordella, Luca and Weiss, Andreas and Ferretti, Stephane Raymond and Almeida, Reinaldo and Bonenfant, Debora and Galli, Giorgio (2021) Therapeutic Assessment of Targeting ASNS Combined with l-Asparaginase Treatment in Solid Tumors and Investigation of Resistance Mechanisms. ACS Pharmacology and Translational Sciences.

Guan, Mingxing and Tian, Yingtao and Zhao, Jibin and Gu, Wayne and Jiang, Xigui and Wang, Xufan and Zhang, Yongbo and Zhang, Xingmin (2021) Safe Scale-Up of a NBS-Involved Bromination Reaction: Thermal Safety Analysis Contributes to Process Optimization. Organic process research & development, 25 (6). pp. 1375-1382.

Guerreiro, Nelson and Jullion, Astrid and Ferretti, Stephane Raymond and Fabre, Claire and Meille, Christophe (2021) Translational Modeling of Anticancer Efficacy to Predict Clinical Outcomes in a First-in-Human Phase 1 Study of MDM2 Inhibitor HDM201. AAPS Journal, 23 (2). ISSN 15507416

Gurinovich, Anastasia and Song, Zeyuan and Zhang, William and Federico, Anthony and Monti, Stefano and Anderson, Stacy L and Jennings, Lori and Barzilai, Nir and Millman, Sofiya and Perls, Thomas T and Sebastian, Paola (2021) Effect of longevity genetic variants on the molecular aging rate. GeroScience. ISSN 25092723


Hadjikyriacou, Andrea and Concannon, John and Sigoillot, Frederic and Antczak, Christophe and Jenkins, Jeremy and Nyfeler, Beat and Jain, Rishi and Tallarico, John and Canham, Steve (2021) Multi-Species Phenotypic Screening across Disease Models of Mucolipidosis Type IV. BioRxiv.

Hadjikyriacou, Andrea and Concannon, John and Sigoillot, Frederic and Antczak, Christophe and Jenkins, Jeremy and Nyfeler, Beat and Jain, Rishi and Tallarico, John and Canham, Steve (2021) Multi-Species Phenotypic Screening across Disease Models of Mucolipidosis Type IV. BioRxiv.

Hall, Peter and Flandre, Thierry and Piaia, Alessandro and Colman, Karyn and Tarnow, Inge and Price, Mark and Haworth, Richard and Vahle, John and Cary, Maurice and Jones, David and Cauvin, Annick (2021) BSTP Review of 12 Case Studies Discussing the Challenges, Pathology, Immunogenicity, and Mechanisms of Inhaled Biologics. Experimental and Toxicologic Pathology. ISSN 0192-62331533-1601

Hall, Peter and Vahle, John and Colman, Karyn (2021) Inspiration and Exasperation: The Challenges of Inhaled Biologics. Toxicologic Pathology. ISSN 15331601

Harlacher, Cornelius and Galli, Bruno and Meinel, Lorenz and Schlauersbach, Jonas and Hanio, Simon and Lenz, Bettina and Vemulapalli, Sahithya and Griesinger, Christian and Pöppler, Ann-Christin (2021) Leveraging bile solubilization of poorly water-soluble drugs by rational polymer selection. Journal of Controlled Release, 330. pp. 36-48. ISSN 18734995

Hartung, Whitney and Schalago, John and Rossi, Claudio and Pavkov, Richard (2021) Software as medical device for connected drug-device combination products. Pharmaceutical engineering.

Hauptmann, Astrid and Hoelzl, Georg and Loerting, Thomas (2021) Optical cryomicroscopy and differential scanning calorimetry of buffer solutions containing cryoprotectants. European Journal of Pharmaceutics and Biopharmaceutics, Volume. pp. 127-140. ISSN 09396411

Hendriks, Bart and Venkatakrishnan, Karthik (2021) Essential (and Largely Untaught) Skills for Clinical Pharmacology in Oncology Drug Development. Clinical Pharmacology and Therapeutics. ISSN 15326535

Heusser, Carolyn and Garad, Sudhakar and Sanchez-Felix, Manuel and Ganish, Ahil (2021) Patient-centric design for systemic peptide delivery: Trends in routes of administration and advancement in drug delivery technologies. Medicine in Drug Discovery.

Heymsfield, Steven and Coleman, Laura and Miller, Ram and Rooks, Daniel and Laurent, Didier and Petricoul, Olivier and Praestgaard, Jens and Swan, Therese and Wade, Thomas and Perry, Robert and Goodpaster, Bret and Roubenoff, Ronenn (2021) Bimagrumab, an Activin Type II Receptor Antagonist, for the Treatment of Obesity and Type 2 Diabetes: A Randomized ClinicalTrial. Journal of the American Medical Association.

Hinterholzer, Arthur and Stanojlovic, Vesna and Huber, Christian and Cabrele, Chiara and Schubert, Mario (2021) Detecting aspartate isomerization and backbone cleavage after aspartate in intact proteins by NMR spectroscopy. Journal of Biomolecular NMR, 75 (1). pp. 71-82. ISSN 15735001

Hoch, Matthias and SATO, MASAHIKO and Zack, Julia and Quinlan, Michelle and Sengupta, Tirtha and Allepuz Palau, Alejandro Javier and Aimone, Paola Daniela and Hourcade-Potelleret, Florence (2021) Pharmacokinetics of asciminib in individuals with hepatic or renal impairment. Journal of Clinical Pharmacology .

Hodoscek, Milan and Kralj, Sebastjan and Podobnik, Barbara and Kunej , Tanja and Konc, Janez (2021) Full therapeutic IgG1 antibody complex with FcγIIa/b and FcγIIIa receptors examined using all-atom molecular dynamics simulations. Frontiers in Chemistry, 9. ISSN 2296-2646

Huth, Felix and Domange, Norbert and Poller, Birk and Vapurcuyan, Natasha and Durrwell, Alexandre and Hanna, Imad and Faller, Bernard (2021) Predicting Oral Absorption for Compounds Outside the Rule of Five Property Space. Journal of pharmaceutical sciences, 110 (6). pp. 2562-2569. ISSN 00223549


INOUE, SATORU and Vaidya, Soniya and Tillmann, Hanns-Christian and SAKITA, YOHEI and Machineni, Surendra Kumar and Heudi, Olivier and Furihata, Kenichi (2021) Pharmacokinetics of indacaterol, glycopyrronium and mometasone furoate administered as an inhaled fixed-dose combination in Japanese and Caucasian healthy subjects. BMC Pulmonary Medicine, 21 (1). p. 18. ISSN 14712466

Israel, Laura and Glueck, Anton and Berger, Marjorie and Coral, Marine and Ceci, Melanie and Unterreiner, Adeline and Rubert, Joelle and Bardet, Maureen and Ginster, Stefanie and Ochsenbein, Alexandra and Martin, Kea and Hoyler, Thomas and Calzascia, Thomas and Wieczorek, Grazyna and Hillenbrand, Rainer and Ferretti, Stephane Raymond and Ferrero, Enrico and Bornancin, Frederic (2021) CARD10 cleavage by MALT1 restricts lung carcinoma growth in vivo. Oncogenesis, 6 (10 (4)). p. 32. ISSN 2157-9024

Iurlaro, Mario and Galli, Giorgio and Jagani, Zainab and Stadler, Michael and Schuebeler, Dirk (2021) Mammalian SWI/SNF continuously restores local accessibility to chromatin. Nature Genetics. ISSN 15461718

Iurlaro, Mario and Stadler, Michael and Galli, Giorgio and Jagani, Zainab and Schuebeler, Dirk (2021) Mammalian SWI/SNF continuously restores local accessibility to chromatin. Nature Genetics. ISSN 15461718


Johansson, David and Rauld, Celine and Roux, Julien and Regairaz Kalenga Kapiamba, Camille and Galli, Edoardo and Callegari, Ilaria and Raad, Layla and Waldt, Annick and Cuttat-Theurillat, Rachel and Roma, Guglielmo and Diebold, Martin and Becher, Burkhard and Kuhle, Jens and Derfuss, Tobias and Carballido, Jose and Sanderson, Nicholas (2021) Mass Cytometry of CSF Identifies an MS-Associated B-cell Population. Neurology(R) neuroimmunology & neuroinflammation, 8 (2). ISSN 23327812

Jordaan, Pierre and Abi-Gerges, Najah and Dumotier, Berengere and Ghetti, Andrea and Urban, Laszlo and Miler, Paul (2021) Cardiotoxic Potential of Hydroxychloroquine, Chloroquine and Azithromycin in adult Human Primary Cardiomyocytes. Toxicological Sciences, e-pub (e-pub). pp. 1-13. ISSN 1096-60801096-0929


Keller, Steve and Quiroz, Jorge and Christopher, Dave and Wickremsinhe, Enaksha and Geng, Wanping and Hawthorne, Glen and James, Christopher and Katterle, Yvonne and Li, Wenkui and Liu, Guowen and Mayer, Andrew and Paton, Martin and Pav, Joseph and Potter, Julian and Vergis, James and Wang, Jonathan (2021) The effectiveness of quality control samples in pharmaceutical bioanalysis. Bioanalysis, 13 (3). pp. 135-145. ISSN 17576199

Kholodar, Svetlana A. and Lang, Geoffrey and Cortopassi, Wilian A. and Iizuka, Yoshie and Brah, Harman S. and Jacobson, Matthew P. and England, Pamela M. (2021) Analogs of the Dopamine Metabolite 5,6-Dihydroxyindole Bind Directly to and Activate the Nuclear Receptor Nurr1. ACS Chemical Biology. ISSN 1554-8929

Kingsley, Laura and He, Xiaohui and McNeill, Matthew and Nelson, John and Nikulin, Victor and Ma, Zhiwei and Lu, Wenshuo and Zhou, Vicki and Manuia, Mari and Kreusch, Andreas and Gao, Mu-Yun and Witmer, Darbi and Vaillancourt, Mei Ting and Lu, Min and Greenblatt, Sarah and Lee, Christian and Bender, Steven and Spraggon, Glen and Michellys, Pierre and Jia, Yong and Haling, Jake and Lelais, Gerald (2021) Structure-based design of selective LONP1 inhibitors for probing in vitro biology. Journal of Medicinal Chemistry. ISSN 0022-26231520-4804

Kingsley, Laura and He, Xiaohui and McNeill, Matthew and Nelson, John and Nikulin, Victor and Ma, Zhiwei and Lu, Wenshuo and Zhou, Vicki and Manuia, Mari and Kreusch, Andreas and Gao, Mu-Yun and Witmer, Darbi and Vaillancourt, Mei Ting and Lu, Min and Greenblatt, Sarah and Lee, Christian and Vashisht, Ajay and Bender, Steven and Spraggon, Glen and Michellys, Pierre and Jia, Yong and Haling, Jake and Lelais, Gerald (2021) Structure-based design of selective LONP1 inhibitors for probing in vitro biology. Journal of Medicinal Chemistry, 64 (8). pp. 4857-4869. ISSN 0022-26231520-4804

Kleinbeck-Riniker, Florian and Schlama, Thierry and Ruch, Thomas and Novick, Scott and Dellas, Nikki and Garcia, Ravi and Ching, Charlene and Bautista, Abby and Homan, David and Alvizo, Oscar and Entwistle, David (2021) Engineering an omega-Transaminase for the Efficient Production of a Chiral Sacubitril Precursor. ACS Catalysis, 11. pp. 3762-3770. ISSN 2155-54352155-5435

Kleinbeck-Riniker, Florian and Schlama, Thierry and Ruch, Thomas and Novick, Scott and Dellas, Nikki and Garcia, Ravi and Ching, Charlene and Bautista, Abby and Homan, David and Alvizo, Oscar and Entwistle, David (2021) Engineering an omega-Transaminase for the Efficient Production of a Chiral Sacubitril Precursor. ACS Catalysis, 11. pp. 3762-3770. ISSN 2155-54352155-5435

Klejbor, I and Shimshek, Derya and Klimaszewska-Łata, J and Velasco-Estevez, M and Moryś, J and Karaszewski, B and Szutowicz, A and Rutkowska, A (2021) EBI2 is expressed in glial cells in multiple sclerosis lesions and its knock-out modulates remyelination in the cuprizone model. European Journal of Neuroscience. ISSN 0953-816X1460-9568

Kolbinger, Frank and Di Padova, Franco E. and Huppertz, Christine and Kuiper, Torsten and Carballido, Jose and Calonder, Claudio and Vogel, Beate Elisabeth and Rondeau, Jean-Michel and Bruin, Gerardus and Deodhar, Atul and Hawkes, Jason and McInnes, Iain B. and Ritchlin, Christopher T. and Rosmarin, David and Schett, Georg and Häusermann, Peter (2021) Secukinumab for the treatment of psoriasis, psoriatic arthritis, and axial spondyloarthritis: Physical and pharmacological properties underlie the observed clinical efficacy and safety. Pharmacology and Therapeutics. ISSN 1879016X

Krantz, Carsten (2021) Review of the Technical, Toxicological, and PKPD Considerations for Conducting Inhalation Toxicity Studies on Biologic Pharmaceuticals—The Outcome of a Cross-Industry Working Group Survey. Toxicologic Pathology. ISSN 15331601

Krell, Christoph and Gallou, Fabrice (2021) Water waste from surfactant chemistry: risk or opportunity? Organic process research & development, 25.

Kreutter, David and Schwaller, Philippe and Reymond, Jean-Louis (2021) Predicting Biotransformations with a Molecular Transformer. Chemical science, 12 (25). pp. 8573-8932. ISSN 2041-6539; 2041-6520

Kälin, RE and Cai, L and Li, Y and Zhang, H and Cheng, J and Zhang, W and Wu, Y and Eisenhut, K and Janssen, P and Schmitt, L and Enard, W and Michels, M and Flüh, C and Hou, M and Kirchleitner, SV and Siller, S and Schiemann, M and Andrä, I and Montanez, E and Giachino, C and Taylor, V and Synowitz, M and Tonn, J and von Baumgarten, L and Schulz, C and Hellmann, I and Glass, R (2021) Dangerous Air: How air pollution affects astrocyte functions. GLIA, 69 (SUPPL ). ISSN 10981136


Lapointe, Guillaume and Skepper, Colin and Holder, Lauren and Armstrong, Duncan and Bellamacina, Cornelia and Blais, Johanne and Bussiere, Dirksen and Bian, Jianwei and Cepura, Cody and Chan, Helen and Dean, Charles and De Pascale, Gianfranco and Dhumale , Bhavesh and Fisher, L. Mark and Fulsundar , Mangesh and Kantariya, Bhavin and Kim, Julie and King, Sean and Kossy, Lauren and Kulkarni, Upendra and Lakshman, Jay and Leeds, Jennifer and Ling, Xiaolan and Lvov, Anatoli and Ma, Sylvia and Malekar, Swapnil and Mckenney, David and Mergo, Wosenu and Metzger Iv, Louis and Mhaske, Keshav and Moser, Heinz and Mostafavi, Mina and Namballa, Sunil and Noeske, Jonas and Osborne, Colin and Patel, Ashish and Patel, Darshit and Patel, Tushar and Piechon, Philippe and Polyakov, Valery and Prajapati, Kruna and Prosen, Katie and Reck, Folkert and Richie, Daryl and Sanderson, Mark and Satasia, Shailesh and Savani, Bhautik and Selvarajah, Jogitha and Sethuraman, Vijay and Shu, Wei and Tashiro, Kyuto and Thompson, Katherine and Vaarla, Krishniah and Vala, Lakhan and Veselkov, Dennis and Vo, Jason and Vora, Bhavesh and Wagner, Beatrix and Wedel, Laura and Williams, Sarah and Yendluri, Satya and Yue, Qin and Yifru, Aregahegn and Zhang, Yong and Rivkin, Alexey (2021) Discovery and Optimization of DNA Gyrase and Topoisomerase IV Inhibitors with Potent Activity Against Fluoroquinolone-Resistant Gram-positive Bacteria. Journal of Medicinal Chemistry. ISSN 0022-26231520-4804

Le Grand, Darren and Gosling, Martin and Baettig, Urs and Bahra, Parmjit and Bala, Kamlesh and Brocklehurst, Cara and Budd, Emma and Butler, Rebecca and Cheung, Atwood and Collingwood, Stephen and Cox, Brian and Danahay, Henry and Edwards, Lee and Everatt, Brian and Glaenzel, Ulrike and Hall, Edward and Hatto, Julia and Howsham, Catherine and Hughes, Glyn and King, Anna and Koehler, Julia and Kulkarni, Swarupa and Lightfoot, Megan and Nicholls, Ian Michael and Page, Christopher and Pergl-Wilson, Giles and Robinson, Richard and Rowlands, David and Steward, Oliver and Taylor, Roger and Tranter, Pamela and Wagner, Beatrix and Williams, Gareth and Wright, Penny and Sandham, David (2021) Discovery of Icenticaftor (QBW251), a Cystic Fibrosis Transmembrane Conductance Regulator Potentiator with Clinical Efficacy in Cystic Fibrosis and Chronic Obstructive Pulmonary Disease. Journal of Medicinal Chemistry, 64 (11). pp. 7241-7260. ISSN 0022-26231520-4804

Lee, Minkyoung and Betz, Charles and Yin, Jianmin and Paatero, Ilkka and Schellinx, Niels and Carte, Adam N and Wilson, Christopher W and Ye, Weilan and Affolter, Markus and Belting, Heinz-Georg (2021) Control of dynamic cell behaviors during angiogenesis and anastomosis by Rasip 1. Development (Cambridge, England). ISSN 1477-9129

Lenz, Jan and Bunjes, Heike and Kwade, Arno and Juhnke, Michael (2021) An Improved Method for the Simultaneous Determination of Water Uptake and Swelling of Tablets. International journal of pharmaceutics, 595 (n/a). p. 120229. ISSN 1873-3476; 0378-5173

Li, Wenkui and Glick, Jim and Hatsis, Panagiotis and Fu, Yunlin and Chin, Harvey and Moench, Paul and Flarakos, Jimmy (2021) An integrated outsourcing practice of nonclinical LC-MS bioanalysis and toxicokinetics at Novartis small molecule drug development. Bioanalysis, 13 (12). pp. 1001-1010. ISSN 17576199

Lima, Fabio and Meisenbach, Mark and Schenkel, Berthold and Sedelmeier, Joerg Mathias (2021) Continuous Flow as an Enabling Technology: A Fast and Versatile Entry to Functionalized Glyoxal Derivatives. Organic & Biomolecular Chemistry. ISSN 1477-05201477-0539

Litchfield, Marcus and Wuest, Melinda and Glubrecht, Daryl and Briard, Emmanuelle and Auberson, Yves and McMullen, Todd and Brindley, David and Wuest, Frank (2021) PET Imaging of Autotaxin in Thyroid and Breast Cancer Models using [18F]PRIMATX. Molecular pharmaceutics.

Liu, Chen and Lu, Henry and Wang, Hongyun and Loo, Alice and Zhang, Xiamei and Yang, Guizhi and Kowal, Colleen and Delach, Scott and Wang, Ye and Goldoni, Silvia and Hastings, Bill and Wong , Karrie and Gao, Hui and Meyer, Matthew and Moody, Susan and LaMarche, Matthew and Engelman, Jeffrey and Williams, Juliet and Hammerman, Peter and Abrams, Tinya and Mohseni, Morvarid and Caponigro, Giordano and Hao, Huaixiang (2021) Combinations with allosteric SHP2 inhibitor TNO155 to block receptor tyrosine kinase signaling. Clinical Cancer Research, 27 (1). pp. 342-354. ISSN 15573265

Lopez, John and G. de la Torre1, Beatriz and Albericio, Fernando and Ramkisson, Shaveer (2021) Refractive Index: The Ultimate Tool for Real-Time Monitoring of Solid-Phase Peptide Synthesis. Greening the Process. Organic Process Research & Development, 25 (https:). pp. 1047-1053. ISSN 1520-586X.

Lu, Yasong and Yang, Shu and Ho, Yu-Yun and Ji, Yan (2021) Ribociclib Population Pharmacokinetics and Pharmacokinetic/Pharmacodynamic Analysis of Neutrophils in Cancer Patients. Journal of Clinical Pharmacology. ISSN 15524604

Luo, Mai and Spradlin, Jessica and Boike, Lydia and Tong, Bingqi and Brittain, Scott and McKenna, Jeffrey and Tallarico, John and Schirle, Markus and Maimone, Thomas and Nomura, Dan (2021) Chemoproteomics-Enabled Ligand Screening Yields Covalent RNF114-Based Degraders that Mimics Natural Product Function. Cell chemical biology. ISSN 24519456

Lustenberger, Philipp and Mathes, Christian and Riss, Bernard and Hueber, Lukas and Dedic, Darija and den Reijer, Carolien and Koenigsberger, Kurt and Napp, Matthias and Schlama, Thierry and Rueegger, Ulrich and Fei, Zhongbo (2021) Using a Johnson-Claisen Rearrangement Strategy to Construct Azaindoles – A Streamlined and Concise Route for the Commercial Process of Fevipiprant. European Journal of Organic Chemistry, 2021 (31). pp. 4490-4494. ISSN 1434-193X1099-0690


Manjunatha, Ujjini and Jumani, Rajiv Satish and Blais, Johanne and Tillmann, Hanns-Christian and Segal, Florencia and Wetty, Dean and Lakshman, Jay and Aziz, Natasha and Chandra, Richa and Ostermeier, Christian and Nuber, Natko and Chen, Wilbur and Chappell, Cynthia and Diagana, Thierry (2021) Opportunities and challenges in developing a Cryptosporidium controlled human infection model for testing novel anti-parasitic agents. ACS infectious diseases, 7. pp. 959-968. ISSN 2373-8227

Manjunatha, Ujjini and Rao, Srinivasa and Smith, Paul and Westhuyzen, Renier van der and Chibale, Kelly (2021) Benzoheterocyclic Oxime Carbamates Active against Mycobacterium tuberculosis: Synthesis, Structure-Activity Relationship, Metabolism, and Biology Triaging. Journal of medicinal chemistry. ISSN 15204804

Marc, Philippe (2021) Data Science in R&D: it is about culture! Pharma Tech Outlook.

Markert, Christian and Thoma, Gebhard and Srinivas, Honnappa and Bollbuck, Birgit and Lueoend, Rainer Martin and Miltz, Wolfgang and Waelchli, Rudolf and Wolf, Romain and Hinrichs, Juergen and Bergsdorf, Christian and Azzaoui, Kamal and Penno, Carlos and Klein, Kai and Wack, Nathalie and Jaeger, Petra and Hasler, Franziska and Beerli, Christian and Loetscher, Pius and Dawson King, Janet and Wieczorek, Grazyna and Numao, Shin and Littlewood-Evans, Amanda and Roehn, Till (2021) Discovery of LYS006, a Potent and Highly Selective Inhibitor of Leukotriene A4 Hydrolase. Journal of medicinal chemistry.

Marques Lopes, Rui and Sprouffske, Kathleen and Sheng, Caibin and Esther, Ujittewaal and Adriana, Wesdorp and Jan, Dahinden and Simon, Wengert and Juan, Diaz Miyar and Umut, Yildiz and Rok, Krese and Bleu, Melusine and Grass, Verena and Mermet-Meillon, Fanny Anne-Marie and Mathias, Eder and Knehr, Judith and Walter, Carbone and Cuttat-Theurillat, Rachel and Waldt, Annick and Altorfer, Marc and Naumann, Ulrike and de Weck, Antoine and Kauffmann, Audrey and Roma, Guglielmo and Schuebeler, Dirk and Galli, Giorgio (2021) Systematic dissection of transcriptional regulatory networks by genome-scale and singlecell CRISPR screens. Science advances, 7. ISSN 2375-2548

Martin, Benjamin and Ladosz, Agnieszka and Battilocchio, Claudio (2021) Flow Chemistry Highlights column in Chimia (monthly contribution). Chimia : international journal for chemistry.

Martin, Eric and Bosc, Nicolas and Felix, Eloy and Saunders, Martin R. and Green, Darren V. S. and Ochoada, Jason and Shelat, Anang A. and Iyer, Preeti and Engkvist, Ola and Verras, Andreas and Duffy, James and Gardner, J. Mark. F. and Leach, Andrew R. (2021) MAIP: A prediction platform for predicting blood-stage malaria inhibitors. Journal of Cheminformatics , 13 (1). p. 13. ISSN 1758-2946

Martin, Eric and Zhu, Xiangwei (2021) Collaborative Profile-QSAR: A Natural Platform for Building Collaborative Models among Competing Companies. Journal of chemical information and modeling, 61 (4). pp. 1603-1616. ISSN 1549960X

Martinez Heredia, Lizbeth and Matero, Sanni and Neumuller, Julie and Juhnke, Michael and Camille, Adler (2021) Process analytical technology as a tool to optimize and accelerate pharmaceutical process development. American Pharmaceutical Review, 24 (4). pp. 28-34.

Martus, Hans-Joerg and Erkman, Linda and Maremanda, Nihal and Elhajouji, Azeddine and Hartmann, Andreas (2021) Comprehensive review of genotoxicity data for diclofenac. Mutation research..

Maziarz, Krzysztof and Jackson-Flux, Henry and Cameron, Pashmina and Sirockin, Finton and Schneider, Nadine and Stiefl, Nikolaus and Brockschmidt, Marc (2021) Learning to Extend Molecular Scaffolds with Structural Motifs. International Conference on Machine Learning.

McIntosh, Avery and Sverdlov, Alex and Yu, Li and Kaufmann, Petra (2021) Clinical design and analysis strategies for development of cell and gene therapies: quantitative drug development in the age of genetic medicine. Clinical pharmacology and therapeutics. pp. 1-9.

Meyer, Angelika and Ibebunjo, Chikwendu and Solovyeva, Elizaveta and Utzinger, Stephan and Eash, John and Dunbar, Andrew W. and Demirci, Sabrina and Naumann, Ulrike and Zhang, Yunyu and Serluca, Fabrizio and Oberhauser, Berndt and Black, Frederique and Rausch, Martin and Trifilieff, Estelle and Hoersch, Sebastian and Trendelenburg, Anne-Ulrike (2021) New insights into molecular changes in skeletal muscle aging and disease: Differential alternative splicing and senescence. Mechanisms of Ageing and Development, 197 (111510). pp. 1-13. ISSN 18726216

Meyer, Fabian and Frey, Raphael and Ligibel, Mathieu and Sager, Emine and Schroer, Kirsten and Snajdrova, Radka and Buller, Rebecca (2021) Modulating chemoselectivity in a Fe(II)/ alpha-ketoglutarate dependent oxygenase for the oxidative modification of a non-proteinogenic amino acid. ACS Catalysis , 11 (10). pp. 6261-6269.

Meyer, Robina M. and Berger, Lukas and Nerkamp, Joerg and Scheler, Stefan and Nehring, Sebastian and Friess, Wolfgang (2021) Identification of Monoclonal Antibody Variants Involved in Aggregate Formation - Part 1: Charge Variants. European journal of pharmaceutics and biopharmaceutics, 158. pp. 123-131. ISSN 1873-3441

Meyer., Robina M. and Berger, Lukas and Nerkamp, Joerg and Scheler, Stefan and Nehring, Sebastian and Friess, Wolfgang (2021) Identification of monoclonal antibody variants involved in aggregate formation – Part 2: Hydrophobicity variants. European Journal of Pharmaceutics and Biopharmaceutics, 160 (March ). pp. 134-142. ISSN 18733441


Nauwelaerts, Nina and Deferm, Neel and Smits, Anne and Bernardini, Chiara and Lammens, Bart and Gandia, Peggy and Panchaud, Alice and Nordeng, Hedvig and Bacci, Maria Laura and Forni, Monica and Ventrella, Domenico and Van Calsteren, Kristel and DeLise, Anthony and Huys, Isabelle and Bouisset-Leonard, Michele and Allegaert, Karel and Annaert, Pieter (2021) A comprehensive review on non-clinical methods to study transfer of medication into breast milk – A contribution from the ConcePTION project. Biomedicine and Pharmacotherapy, 136. p. 111038. ISSN 19506007

Niederwieser, Sylwia and Passecker, Armin and Alder, Arne and Carrington, Eilidh and van de Vegte-Bolmer, Marga and van Gemert, Geert-Jan and van der Starre, Alex and Beck, Hans-Peter and Sauerwein, Robert W and Kooij, Taco W A and Brancucci, Nicolas M B and Proellochs, Nicholas I and Gilberger, Tim-Wolf and Voss, Till S (2021) CRISPR/Cas9-engineered inducible gametocyte producer lines as a valuable tool for Plasmodium falciparum malaria transmission research. Nature communications, 12 (1). p. 4806. ISSN 2041-1723

Norby, Ulrike and Cuppers, Benedikte-Noël and Hristoskova, Sashka Angelova and Desai, Monali and Harmark, Linda and Steel, Michael (2021) Online information discrepancies regarding safety of medicine use during pregnancy and lactation: a ConcePTION study. Expert Opinion on Drug Safety, https: (https:). pp. 1-8. ISSN

Nyquist, Michael D and et al, et al (2021) Selective androgen receptor modulators activate the canonical prostate cancer androgen receptor program and repress cancer growth. Journal of Clinical Investigation, 131 (10). pp. 1-15. ISSN 15588238

Nörpel, Julia and Cavadini, Simone and Schenk, Andreas and Graff-Meyer, Alexandra and Hess, Daniel and Seebacher, Jan and Chao, Jeffrey A and Bhaskar, Varun (2021) Structure of the human C9orf72-SMCR8 complex reveals a multivalent protein interaction architecture. PLoS biology, 19 (7). ISSN 1545-7885


Papadopoulou, Athena and Meierhofer, Jasmin and Meyer, Fabian and Hayashi, Takahiro and Schneider, Samuel and Sager, Emine and Rebecca, Buller (2021) Re-programming and optimization of a L-proline cis-4-hydroxylase for the cis-3-halogenation of its native substrate. ChemCatChem.. ISSN 1867-38801867-3899

Parmentier, Michael and Baudoin, Olivier and Antien, Kevin and Geraci, Andrea (2021) A New Dioxazolone for the Synthesis of 1,2-Aminoalcohols via Iridium(III)-Catalyzed C(sp3)–H Amidation. Angewandte Chemie International Edition. ISSN 1433-78511521-3773

Parmentier, Michael and Debrauwer, Vincent and Leito, Ivo and Lokov, Mart and Tshepelevitsh, Sofja and Blanchard , Nicolas and Bizet, Vincent (2021) Synthesis and Physico-Chemical Properties of 2-SF5-(Aza)Indoles, A New Family of SF5-Heterocycles. ACS Organic & Inorganic Au. ISSN 2694-247X2694-247X

Parmentier, Michael and Li, Wei and Dalton, Charlotte and Diorazio, Louis and Doerfler, Jaika and Engl, Olivier and Han, Zhengxu and Howell, Gareth and Hutchby, Marc and Latham, Jonathan and McLaws, Mark and Munday, Rachel and Navarro, Antonio and Pawlas, Jan and Roiban, Doru and Terrett, Jack and Treitler, Daniel and Zeng, Mingshuo and Steven, Alan (2021) Green Chemistry Articles of Interest to the Pharmaceutical Industry. Organic Process Research & Development. ISSN 1083-61601520-586X

Pavlova, Anna and Lynch, Diane and Diadone, Isabella and Zanetti-Polzi, Laura and Smith, Micholas Dean and Chipot, Chris and Kneller, Daniel and Kovalevsky, Andrey and Coates, Leighton and Velez-Vega, Camilo and Golosov, Andrei and Dickson, Callum and Duca, Jose and Vermaas, Josh and Pang, Yui Tik and Acharya, Atanu and Parks, Jerry and Smith, Jeremy and Gumbart, James (2021) Inhibitor binding influences the protonation states of histidines in SARS-CoV-2 main protease. Chemical science. ISSN 2041-6539; 2041-6520

Pikman, Yana and Tasian, Sarah K and Sulis, Maria Luisa and Stevenson, Kristen and Blonquist, Traci M and Apsel Winger, Beth and Cooper, Todd M and Pauly, Melinda and Maloney, Kelly W and Burke, Michael J and Brown, Patrick A and Gossai, Nathan and McNeer, Jennifer L and Shukla, Neerav N and Cole, Peter D and Kahn, Justine M and Chen, Jing and Barth, Matthew J and Magee, Jeffrey A and Gennarini, Lisa and Adhav, Asmani A and Clinton, Catherine M and Ocasio-Martinez, Nicole and Gotti, Giacomo and Li, Yuting and Lin, Shan and Imamovic, Alma and Tognon, Cristina E and Patel, Tasleema and Faust, Haley L and Contreras, Cristina F and Cremer, Anjali and Cortopassi, Wilian A and Garrido Ruiz, Diego and Jacobson, Matthew P and Dharia, Neekesh V and Su, Angela and Robichaud, Amanda L and Saur Conway, Amy and Tarlock, Katherine and Stieglitz, Elliot and Place, Andrew E and Puissant, Alexandre and Hunger, Stephen P and Kim, Annette S and Lindeman, Neal I and Gore, Lia and Janeway, Katherine A and Silverman, Lewis B and Tyner, Jeffrey W and Harris, Marian H and Loh, Mignon L and Stegmaier, Kimberly (2021) Matched Targeted Therapy for Pediatric Patients with Relapsed, Refractory or High-risk Leukemias: A Report from the LEAP Consortium. Cancer discovery. ISSN 2159-8290

Pikman, Yana and Tasian, Sarah K. and Sulis, Maria Luisa and Stevenson, Kristen and Blonquist, Traci M. and Apsel Winger, Beth and Cooper, Todd M. and Pauly, Melinda and Maloney, Kelly W. and Burke, Michael J. and Brown, Patrick A. and Gossai, Nathan and McNeer, Jennifer L. and Shukla, Neerav N. and Cole, Peter D. and Kahn, Justine M. and Chen, Jing and Barth, Matthew J. and Magee, Jeffrey A. and Gennarini, Lisa and Adhav, Asmani A. and Clinton, Catherine M. and Ocasio-Martinez, Nicole and Gotti, Giacomo and Li, Yuting and Lin, Shan and Imamovic, Alma and Tognon, Cristina E. and Patel, Tasleema and Faust, Haley L. and Contreras, Cristina F. and Cremer, Anjali and Cortopassi, Wilian A. and Garrido Ruiz, Diego and Jacobson, Matthew P. and Dharia, Neekesh V. and Su, Angela and Robichaud, Amanda L. and Saur Conway, Amy and Tarlock, Katherine and Stieglitz, Elliot and Place, Andrew E. and Puissant, Alexandre and Hunger, Stephen P. and Kim, Annette S. and Lindeman, Neal I. and Gore, Lia and Janeway, Katherine A. and Silverman, Lewis B. and Tyner, Jeffrey W. and Harris, Marian H. and Loh, Mignon L. and Stegmaier, Kimberly (2021) Matched Targeted Therapy for Pediatric Patients with Relapsed, Refractory, or High-Risk Leukemias: A Report from the LEAP Consortium. Cancer Discovery, 11 (6). pp. 1424-1439. ISSN 2159-8274

Pistorius, Dominik and Buntin, Kathrin and Weber, Eric and Richard, Etienne and Bouquet, Caroline and Wollbrett, Severine (2021) Genetic engineering of Chromobacterium vaccinii DSM 25150 for improved production of FR900359. ChemRxiv (

Prabhath , Anupama and Vernekar , Varadraj N and Vasu , Vignesh and Badon, Mary and Avochinou , Jean-Emmanuel and Asandei , Alexandru D and Kumbar , Sangamesh G and Weber, Eckhard and Laurencin , Cato T (2021) In Vitro Kinetic Degradation and In Vivo Biocompatibility Evaluation of Polycaprolactone-Based Growth Factor Delivery Matrices in the Rotator Cuff. Journal of Biomedical Materials Research Part A. ISSN 1549-32961552-4965


Rago, Florencia and Rodrigues, Lindsey and Bonney, Megan and Sprouffske, Kathleen and Kurth, Esther and Elliott, GiNell and Ambrose, Jessi and Aspesi Jr, Peter and Oborski, Justin and Chen, Julie and McDonald III, Earl and Mapa, Felipa and Ruddy, David and Kauffmann, Audrey and Abrams, Tinya and Bhang, Hyo-eun and Jagani, Zainab (2021) Exquisite Sensitivity to Dual BRG1/BRM ATPase Inhibitors Reveals Broad SWI/SNF Dependencies in Acute Myeloid Leukemia. BioRxiv.

Risitano, Antonio and Röth, Alexander and Soret, Juliette and Frieri, Camilla and Sicre de Fontbrune, Flore and Marano, Luana and Alashkar, Ferras and Rozenberg, Izabela and Milojevic, Julie and End, Peter and Nidamarthy, Prasanna and Junge, Guido and Peffault de Latour, Regis (2021) Addition of iptacopan, an oral factor B inhibitor, to eculizumab in patients with paroxysmal nocturnal haemoglobinuria and active haemolysis: an open-label, single-arm, phase 2, proof-of-concept trial. The Lancet. Haematology. ISSN 2352-3026

Robbins, Jeremy M and Peterson, Bennet and Schranner, Daniela and Tahir, Usman A and Keyes, Michelle and Katz, Daniel and Jean Beltran, Pierre M and Barber, Jacob L and Baumgartner, Christian and Carr, Steven A and Ghosh, Sujoy and Jennings, Lori and Shen, Changyu and Sarzynski, Mark A and Bouchard, Claude and Gerszten , Robert E (2021) Human plasma proteomic profiles indicative of cardiorespiratory fitness. Nature Metabolism. ISSN 25225812

Robbins, Lindsey A. and Green-Miller, Angela R. and Johnson, Jay S. and Gaskill, Brianna N. (2021) One Is the Coldest Number: How Group Size and Body Weight Affect Thermal Preference in Weaned Pigs (3 to 15 kg). Animals, 11 (5). p. 1447. ISSN 2076-2615

Rodon, Jordi and Argiles, Guillem and Connolly, Roisin and Vaishampayan, Ulka and de Jonge, Maja and Garralda, Elena and Giannakis, Marios and Smith, David C. and Dobson, Jason and McLaughlin, Margaret and Seroutou, Abdelkader and Ji, Yan and Morawiak, Jennifer and Moody, Susan and Janku, Filip (2021) Phase I study of single-agent WNT974 a first-in-class Porcupine inhibitor, in patients with advanced solid tumors. British journal of cancer : BJC, 125. pp. 28-37. ISSN 1532-1827

Rodriguez Perez, Raquel and Bajorath, Jürgen (2021) Feature importance correlation from machine learning indicates functional relationships between proteins and similar compound binding characteristics. Scientific reports, 11.

Roehle, Kevin and Qiang, Li and Ventre, Katherine and Heid , Daniel and Ali, Lestat and Lenehan, Patrick and Heckler, Max and Crowley, Stephanie and Stump, Courtney and Ro, Gabrielle and Godicelj, Anze and Bhuiyan, Aladdin and Yang, Annan and Quiles del Rey, Maria and Biary, Tamara and Luoma, Adrienne and Bruck, Patrick and Tegethoff, Jana and Nopper, Svenja and Li, Jinyang and Byrne, Katelyn and Pelletier, Marc and Wucherpfennig , Kai and Stanger , Ben and Akin, James and Mancias, Joe and Agudo, Judith and Dougan, Michael and Dougan, Stephanie (2021) cIAP1/2 antagonism eliminates MHC class I-negative tumors through T cell-dependent reprogramming of mononuclear phagocytes. Science translational medicine, 13. ISSN 1946-6242

Rowlands, Marianna and Segal, Florencia and Hartl, Dominik (2021) Myeloid-Derived Suppressor Cells as a Potential Biomarker and Therapeutic Target in COVID-19. Frontiers in immunology, 12. ISSN 1664-3224

Rueeger, Heinrich and Lueoend, Rainer Martin and Machauer, Rainer and Veenstra, Siem and Holzer, Philipp and Hurth, Konstanze and Voegtle, Markus and Frederiksen, Mathias and Rondeau, Jean-Michel and Tintelnot-Blomley, Marina and Jacobson, Laura and Staufenbiel, Matthias and Laue, Grit and Neumann, Ulf (2021) Synthesis of the Potent, Selective, and Efficacious β-Secretase (BACE1) Inhibitor NB-360. Journal of Medicinal Chemistry, 64 (8). pp. 4677-4696. ISSN 0022-26231520-4804


SEBASTIANI, PAOLA and MONTI, STEFANO and FEDERICO, ANTHONY and Morris, Melody and GURINOVICH, ANASTASIA and TOSHIKO, TANAKA and BHUTKAR, APARNA and ANDERSON, STACY L and FERRUCCI, LUIGI and Glass, David and Jennings, Lori and PERLS, THOMAS T (2021) Protein signatures of centenarians and their offspring suggest centenarians age slower than other humans. Aging Cell. ISSN 14749726

Samant, Tanay and Yang, Shu and Miller, Michelle and Ji, Yan (2021) Pharmacokinetics of Ribociclib in Subjects With Hepatic Impairment. Journal of Clinical Pharmacology, 61 (8). pp. 1001-1009. ISSN 15524604

Sanchez, Carlos and Acker, Chris and Gray, Audrey and Varadarajan, Malini and An, Shaojian and Paula, Steve and Lindeman, Alicia and Alford, John and Reece-Hoyes, John and Russ, Carsten and Cochran, Nadire and McAllister, Gregory and Craig, Lucas and Capre, Ketthsy and Doherty, Christian and Elwood, Fiona (2021) Genome-wide CRISPR screen identifies protein pathways modulating tau protein levels in neurons. Communications biology, 4 (1). p. 736. ISSN 23993642

Sanchez-Felix, Manuel and Li, Yimeng and Ariotti, Nicholas and Aghaei-Ghareh-Bolagh, Behnaz and Pandzic, Elvis and Ganda, Sylvia and Willcox, Marc and Stenzel, Martina (2021) Inhibitive S. aureus Infection to HUVECs Induced by Trehalose and Glucose-functionalized Gold Nanoparticles. Angewandte Chemie.

Sanchez-Felix, Manuel and Zulick, Elizabeth and Sadler, Lauren-Ash and Bladon, Mariluci (2021) Education Pathway to Diversify STEM Workforce: A Call to Action for a Collaborative Ecosystem. American Association of Pharmaceutical Science Newsmagazine, August (1).

Santandrea, Ernesto and Waldraff, Christine and Gerber, Gilles and Moreau, Mael and Beney, Pascal (2021) Development of the late-phase manufacturing process to ZPL389: control of process impurities by enhanced process knowledge. Organic process research & development.

Saravanan, Chandrassegar and Flandre, Thierry and Hodo, Carolyn and Lewis, Anne and Mecklenburg, Lars and Romeike, Annette and Turner, Oliver and Yen, Hsi-Y (2021) Research Relevant Conditions and Pathology in Nonhuman Primates. ILAR Journal. ISSN 1084-20201930-6180

Schmelzer, Bernhard and Mischo, André and Innerbichler, Franz (2021) Statistically significant versus practically relevant trend in stability data. PDA journal of pharmaceutical science and technology. ISSN 19482124

Schuhmacher, Alexander and Brieke, Clara and Gassmann, Oliver and Hinder, Markus and Hartl, Dominik (2021) Systematic risk identification and assessment using a new risk map in pharmaceutical R&D. Drug discovery today, 21. S1359--6446.

Schuhmacher, Alexander and Wilisch, Lukas and Kandelbauer, Andreas and Hinder, Markus and Gassmann, Oliver (2021) R&D efficiency of leading pharmaceutical companies - a 20-year analysis. Drug Discovery Today, 2021 M (S1359-). pp. 36-41.

Schuhmacher, Alexander and Wilisch, Lukas and Kandelbauer, Andreas and Hinder, Markus and Gassmann, Oliver (2021) R&D efficiency of leading pharmaceutical companies — a 20-year analysis. Drug discovery today, May 20.

Schustak, Joshua and Twarog, Michael and Wu, Xiaoqiu and Wu, Henry and Huang, Qian and Bao, Yi (2021) Mechanism of nucleic acid sensing in retinal pigment epithelium (RPE): RIG-I mediates type I interferon response in human RPE. Journal of Immunology Research, 2021. pp. 1-14. ISSN 2314-71562314-8861

Schutten, Melissa and Knoblaugh, Sue and Salas , Elisa and Edmondson, Elijah and Cossic, Brieuc and Everitt, Jeffrey and Saravanan, Chandrassegar and Schmidt, Sarah and Schumacher, Vanessa and Zimmerman, Kurt (2021) Letter to the Editor Regarding “Pathology Informatics Education Committee of the American College of Veterinary Pathologists (ACVP)”. Toxicologic pathology, 49 (4). pp. 709-710. ISSN 1533-1601; 0192-6233

Schutzius, Gabi and Hauer, Christian and Bergling, Sebastian and Tortelli, Federico and Fuchs, Florian and Renner, Steffen and Guagnano, Vito and Cotesta, Simona and Rueeger, Heinrich and Faller, Michael and Bouchez, Laure and Salathe, Adrian and Nigsch, Florian and Richards, Shola and Louis, Malvina Caroline and Gruber, Viktoria and Aebi, Alexandra and Turner, Jonathan and Grandjean, Frederic and Li, Jun and Dimitri, Christopher and Thomas, Jason and Schirle, Markus and Blank, Jutta and Drueckes, Peter and Vaupel, Andrea and Tiedt, Ralph and Manley, Paul and Klopp, Julia and Hemmig, Rene and Zink, Florence and Leroy, Nelly and Carbone, Walter and Roma, Guglielmo and Gubser Keller, Caroline and Dales, Natalie and Beyerbach, Armin and Zimmerlin, Alfred Gilbert and Bonenfant, Debora and Terranova, Remi and Berwick, Amy and Sahambi, Sukhdeep and Reynolds, Aimee and Jennings, Lori and Ruffner, Heinz and Tarsa, Peter and Bouwmeester, Antonius and Driver, Vickie and Frederiksen, Mathias and Lohmann, Felix and Kirkland, Susan (2021) BET bromodomain inhibitors regulate keratinocyte plasticity. Nature Chemical Biology, 17 (3). pp. 280-290. ISSN 15524469

Sedlmayer, Ferdinand and Woischnig, Anne-Kathrin and Unterreiner, Vincent and Fuchs, Florian and Baeschlin, Daniel and Khanna, Nina and Fussenegger, Martin (2021) 5-Fluorouracil blocks quorum-sensing of biofilm-embedded methicillin-resistant Staphylococcus aureus in mice. Nucleic Acids Research. ISSN 0305-10481362-4962

Seo, Hyungseok and González-Avalos, Edahí and Zhang, Wade and Ramchandani, Payal and Yang, Chao and Lio, Chan-Wang J and Rao, Anjana and Hogan, Patrick G (2021) BATF and IRF4 cooperate to counter exhaustion in tumor-infiltrating CAR T cells. Nature immunology. ISSN 1529-2916

Seo, Hyungseok and González-Avalos, Edahí and Zhang, Wade and Ramchandani, Payal and Yang, Chao and Lio, Chan-Wang J. and Rao, Anjana and Hogan, Patrick G. (2021) BATF and IRF4 cooperate to counter exhaustion in tumor-infiltrating CAR T cells. Nature Immunology. ISSN 1529-2908

Sing, Tobias and Hoefling, Holger and Hossain, Imtiaz and Boisclair, Julie and Doelemeyer, Arno and Flandre, Thierry and Piaia, Alessandro and Romanet, Vincent and Santarossa, Gianluca and Saravanan, Chandrassegar and Spiegel, Stephan and Sutter, Esther and Turner, Oliver and Wuersch, Kuno and Moulin, Pierre (2021) HistoNet: A Deep Learning-Based Model of Normal Histology. Toxicologic Pathology, 49 (4). pp. 784-797. ISSN 15331601

Singh, Ashish Kumar and Schauer, Tamas and Pfaller, Lena and Straub, Tobias and Mueller-Planitz, Felix (2021) The biogenesis and function of nucleosome arrays. bioRxiv.

Song, Shuang and Cao, Chun and Choukrallah, Mohamed-Amin and Tang, Fengyuan and Christofori, Gerhard and Kohler, Hubertus and Wu, Fabian and Fodor, Barna and Frederiksen, Mathias and Willis, Simon N. and Jackson, Jacob and Nutt, Stephen L. and Dirnhofer, Stefan and Stadler, Michael and Matthias, Patrick (2021) OBF1 and Oct factors control the germinal center transcriptional program. Blood, 137 (21). pp. 2920-2934. ISSN 15280020

Stančič, Metka and Cvijic, Tamara and Kuzman, Drago and Mravljak, Rok and Gunčar, Gregor and Podgornik, Aleš (2021) Application of lectin immobilized on polyHIPE monoliths for bioprocess monitoring of Fc-fusion surface glycosylated protein. Journal of chromatography B : biomedical sciences and applications.

Straube, Frank and Cirera Salinas, Daniel (2021) Membrane-tethered mucins and lubricin mediate the interfacial properties of model ocular epithelial surfaces. Advanced Science. ISSN 2198-38442198-3844

Streffer, Johannes and Treyer, Valerie and Buck, Alfred and Ametamey, Simon and Blagoev, Milen and Schmidt, Mark and Gautier, Aurelie and Maguire, Paul and Auberson, Yves and Vranesic, Ivan-Toma and Gomez-Mancilla, Baltazar and Gasparini, Fabrizio (2021) Regional brain mGluR5 receptor occupancy following single oral doses of mavoglurant as measured by [11C]-ABP688 PET imaging in healthy volunteers. NeuroImage, 230. ISSN 10538119

Streubel-Gallasch, L and Giusti, V and Sandre, M and Tessari, I and Plotegher, N and Giusto, E and Masato, A and Iovino, L and Battisti, I and Arrigoni, G and Shimshek, Derya and Greggio, E and Tremblay, ME and Bubacco, L and Erlandsson, A and Civiero, L (2021) Parkinson’s Disease–Associated LRRK2 Interferes with Astrocyte-Mediated Alpha-Synuclein Clearance. Molecular Neurobiology. ISSN 15591182

Sukseree, Supawadee and Bakiri, Latifa and Paloma-Irigoyen, Marta and Uluckan, Ozge and Petzelbauer, Peter and Wagner, Erwin (2021) Sequestosome 1/p62 enhances chronic skin inflammation. The Journal of allergy and clinical immunology. ISSN 10976825

Sverdlov, Alex and Curcic, Jelena and Hannesdottir, Kristin and De Luca, Valeria and Ambrosetti, Francesco and Zhang, Bingsong and Praestgaard, Jens and Vallejo, Vanessa and Dolman, Andrew and Gomez-Mancilla, Baltazar and Biliouris, Konstantinos and Deurinck, Mark and Cha, Jang-Ho and Cormack, Francesca and Anderson, John J. and Bott, Nicholas, T. and Peremen, Ziv and Issachar, Gil and Joachim, Dale and Kas , Martien and Zhuparris, Ahnjili and Jacobs, Gabriel (2021) A study of new exploratory tools, digital technologies and biomarkers to characterize depression. Frontiers in psychiatry, 12. ISSN 1664-0640


Tan, Susanne and Schellenberg, Doerte and Morton, Kayce and Dokras, Anuja and Seufert, Joachim and Zwanziger, Denise and Dunschen, Karin and Zakaria, Marjorie and Huseinovic, Neda and Basson, Craig and Fuhrer, Dagmar and Hinder, Markus (2021) Licogliflozin versus placebo in women with polycystic ovary syndrome: A randomized, double-blind, phase 2 trial. Diabetes, Obesity and Metabolism. pp. 1-5. ISSN 14631326

Thomas, Ranjeny and Carballido, Jose and Wesley, Johnna D and Ahmed, Simi (2021) Overcoming obstacles in the development of antigen-specific immunotherapies for type 1 diabetes. Frontiers in immunology, 12. ISSN 1664-3224

To, Jeremy and Quackenbush, Doug and Rowell, Emily and Li, Lilin and Lo, Frederick and Horman, Shane (2021) A biomimetic assay platform for the interrogation of antigen-dependent anti-tumor T-cell function. Communications biology, 4. p. 56. ISSN 2399-3642

Tsai, Wan-Chen and Aleem, Ansari Mukhtar and Whittington, Chris and Cortopassi, Wilian A. and Kalyanaraman, Chakrapani and Baroz, Angel and Iavarone, Anthony T. and Skrzypczak-Jankun, Ewa and Jacobson, Matthew P. and Offenbacher, Adam R. and Holman, Theodore (2021) Mutagenesis, Hydrogen–Deuterium Exchange, and Molecular Docking Investigations Establish the Dimeric Interface of Human Platelet-Type 12-Lipoxygenase. Biochemistry, 60 (10). pp. 802-812. ISSN 0006-2960

Tummino, Tia and Rezelj, Veronica and Fischer, Benoit and Fischer, Audrey and o'Donnel, Henry and Monel, Blandine and Vallet, Thomas and Zhang, Ziyang and Alon, Assaf and Lyu, Jiankun and Schadt, Heiko and White, Kris and o'Meara, Matthew and Krogan , Nevan and Shokat, Kevan and Urban, Laszlo and Kruse, Andrew and Garcia-Sastre, Adolfo and Schwarz, Olivier and Moretti, Francesca and Vignuzzi, Marco and Pognan, Francois and Shoichet, Brian (2021) Drug-induced phospholipidosis confounds drug repurposing for SARS-CoV-2. Science. ISSN 0036-8075

Turner, Oliver and Rudmann, Daniel and Knight, Brian and Zuraw, Aleksandra and Litjens, Geert (2021) Mini Review: The Last Mile—Opportunities and Challenges for Machine Learning in Digital Toxicologic Pathology. Toxicologic pathology.


Unterreiner, Adeline and Rubert, Joelle and Kauffmann, Muriel and Fruhauf, Alice and Heiser, Diane and Erbel, Paulus and Schlapbach, Achim and Eder, Joerg and Bodendorf, Ursula and Boettcher, Andreas and Farady, Christopher and Bornancin, Frederic (2021) Pharmacological inhibition of IKKβ dampens NLRP3 inflammasome activation after priming in the human myeloid cell line THP-1. Biochemical and biophysical research communications : BBRC, 545. pp. 177-182. ISSN 0006291X


Valencia, Jessica and Megnin, Michelle and Collyar, Deborah and Guerreiro, Debra and Kashuba, Maureen and Klim, Lotte and Murray, Caragh and Patrick, Susan and Schindler, Thomas and Vashisht, Vidhi (2021) Presenting secondary endpoints in plain language clinical trial result summaries: Considerations for emerging practice. 'Medical Writing' - Quarterly publication produced by European Medical Writers Association , Volume (Issue ). pp. 58-67. ISSN 2047-4814

Velasco-Estevez, M and Koch, N and Klejbor, I and Laurent, Stephane and Dev, K and Szutowicz, A and Sailer, Andreas and Rutkowska, A (2021) Ebi2 is temporarily upregulated in mo3.13 oligodendrocytes during maturation and regulates remyelination in the organotypic cerebellar slice model. International Journal of Molecular Sciences, 22 (9). ISSN 14220067

Ventrella, Domenico and Ashkenazi, Nurit and Elmi, Alberto and Allegaert, Karel and Aniballi, Camilla and DeLise, Anthony and Devine, PJ and Smits, Anne and Steiner, Lilach and Forni, Monica and Bouisset-Leonard, Michele and Bacci, Maria Laura (2021) Animal models for in vivo lactation studies: anatomy, physiology and milk compositions in the most used non-clinical species, a contribution from the ConcePTION project. Animals, 11 (3). pp. 714-733. ISSN 2076-2615

Vidal, Justin and Colman, Karyn and Bhaskaran, Manoj and de Rijk, Eveline and Fegley, Darren and Haplern, Wendy and Jacob, Binod and Kandori, Hitoshi and Manickam, Balasubramanian and McKeag, Sean and Parker, George A. and Regan, Karen S. and Sefing, Benjamin and Thibodeau, Michael and Vemireddi, Vimala and Werner, Jonathan and Zalewska, Aleksandra (2021) Scientific and Regulatory Policy Committee Best Practices*: Documentation of Sexual Maturity by Microscopic Evaluation in Nonclinical Safety Studies. Toxicologic Pathology. ISSN 15331601

Vittal, Shivva and Fink, Martin and Lowe, Philip J (2021) Improving priors for human monoclonal antibody linear pharmacokinetic parameters by using half-lives from non-human primates. Journal of Pharmacokinetics and Pharmacodynamics. ISSN 15738744

Vorherr, Thomas (2021) Important considerations related to permeability of peptides. Chimia., 75 (6). pp. 522-524.

Vulpetti, Anna and Dalvit, Claudio (2021) Hydrogen Bond Acceptor Propensity of different Fluorine Atom Types: An Analysis of Experimentally- and Computationally-derived Parameters. Chemistry (Weinheim an der Bergstrasse, Germany), 27 (34). pp. 8764-8773. ISSN 15213765

van Hoogevest, Peter and Tiemessen, Harry and Metselaar, Josbert and Fahr, Alfred (2021) The Use of Phospholipids to make Pharmaceutical Form Line Extensions. European Journal of Lipid Science and Technology. ISSN 1438-76971438-9312


Waehle, Verena and Ungricht, Rosemarie and Hoppe, Philipp and Betschinger, Joerg (2021) The tumor suppressor WT1 drives progenitor cell progression and epithelialization to prevent Wilms tumorigenesis in human kidney organoids. Stem cell reports, 16. pp. 1-11. ISSN 2213-6711

Walker, Keenan A. and Chen, Jingsha and Zhang, Jingning and Fornage, Myriam and Tin, Adrienne and Daya, Natalie and Hoogeveen, Ron C and Wu, Aozhou and Sullivan, Kevin J and Ganz, Peter and Zeger, Scott L and Yang, Yunju and Gudmundsson, Elias F and Emilsson, Valur and Launer, Lenore J and Jennings, Lori and Gudnason, Vilmundur and Chatterjee, Nilanjan and Gottesman, Rebecca F and Mosley, Thomas H and Boerwinkle, Eric and Ballantyne, Christie M and Coresh, Josef and Zhou, Linda and Grams, Morgan E (2021) Large-scale plasma proteomic analysis identifies proteins and pathways associated with dementia risk. Nature Aging.

Walles, Markus (2021) Meeting report of the first European Biotransformation Workshop. Xenobiotica. pp. 1-6. ISSN 34284691

Wang, Hui-Qin and Mulford, Iain and Sharp, Fiona and Liang, Jinsheng and Kurtulus-Aksoylar, Sema and Trabucco, Gina and Quinn, David and Longmire, Tyler and Patel, Nidhi and Shirley, Matt and Chen, Yan and Wang, Hao and Ruddy, David and Fabre, Claire and Williams, Juliet and Hammerman, Peter and Mataraza, Jennifer and Platzer, Barbara and Halilovic, Ensar (2021) Inhibition of MDM2 promotes antitumor responses in p53 wild-type cancer cells through their interaction with the immune and stromal microenvironment. Cancer Research, 81 (11). pp. 3079-3091. ISSN 15387445

Wang, Xinting and Bartels, Christian and Kulkarni, Swarupa and Sangana, Ramachandra and Jain, Monish and Zack, Julia and Yu, Jing (2021) Population Pharmacokinetic Analysis of Fevipiprant in Healthy Subjects and Asthma Patients using a Tukey's g-and-h Distribution. Drug Research. ISSN 21949387

Wang-Lakshman, Lydia and Mendonza, Anisha and Huber, Roland and Walles, Markus and He, Yan-Ling and Jarugula, Venkateswar (2021) Pharmacokinetics, Metabolism, and Excretion of Licogliflozin, a Dual Inhibitor of SGLT1/2, in Rats, Dogs, and Humans. Xenobiotica.

Wang-Lakshman, Lydia and Zhuang, Miao and Wang, Lai and Gu, Helen and Gu, Jessie and McNamara, Elizabeth and Walles, Markus and Woessner, Ralph and Camenisch, Gian P. and Einolf, Heidi and Chen, Jin (2021) Evaluation of the Absorption, Metabolism, and Excretion of a Single Oral 1 mg Dose of Tropifexor in Healthy Male Subjects and the Concentration Dependency of Tropifexor Metabolism. Drug metabolism and disposition, 49 (7). pp. 548-562. ISSN 1521-009X

Weiss, Markus and Cain, Meredith and Langenickel, Thomas and Kulkarni, Swarupa and Shah, Bharti and Rahmanzadeh, Gholamreza and Poller, Birk and Vemula, Janardhana Rao (2021) Clinical investigation of metabolic and renal clearance pathways contributing to the elimination of fevipiprant using probenecid as perpetrator. Drug metabolism and disposition, 49 (5). pp. 389-394. ISSN 1521-009X

Woicke, Jochen and Al-Haddawi, Muthafar M and Bienvenu, Jean-Guy and Caverley Rae, Jessica M and Chanut, Franck J and Colman, Karyn and Cullen, John and Davis, Wendell and Fukuda, Ryo and Huisinga, Maike and Junker Walker, Ursula and Kai, Kiyonori and Kovi, Ramesh C and Macri, Nicholas P and Marxfeld, Heike-Antje and Nikula, Kristin J and Pardo, Ingrid D and Rosol, Thomas J and Sharma, Alok K and Singh, Bhanu P and Tamura, Kazutoshi and Thibodeau, Michael S and Vezzali, Enrico and Vidal, Justin D and Meseck, Emily (2021) International Harmonization of Nomenclature and Diagnostic Criteria (INHAND): Nonproliferative and Proliferative Lesions of the Dog. Toxicologic Pathology, 49 (1). pp. 5-109. ISSN 15331601

Wuensch, Isabell and Finke, Jan and John, Edgar and Juhnke, Michael and Kwade, Arno (2021) The influence of particle size on the application of compression and compaction models for tableting. International journal of pharmaceutics, 599 (n/a). 120424-n/a. ISSN 0378-5173

Wünsch, Isabell and Michel, Stephanie and Finke, Jan Henrik and John, Edgar and Juhnke, Michael and Kwade, Arno (2021) How can single particle compression and nanoindentation contribute to the understanding of pharmaceutical powder compression? European Journal of Pharmaceutics and Biopharmaceutics, 165 (n/a). pp. 203-218. ISSN 0939-6411


Zhang, Zhe (2021) Solving Complex Biologics Truncation Problems by Top-Down Mass Spectrometry. Journal of the American Society for Mass Spectrometry. ISSN 1879-1123; 1044-0305

Zhou, Lili and Miller, Caitlyn and Miraglia, Loren and Mendiola, Angelica and Mure, Ludovic S. and Panda, Satchidananda and Xiao, Changchun and Kay, Steve (2021) A genome-wide microRNA screen identifies the microRNA-183/96/182 cluster as a modulator of circadian rhythms. Proceedings of the National Academy of Sciences, 118 (1). ISSN 0027-84241091-6490

This list was generated on Thu Sep 16 06:00:08 2021 UTC.


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