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Items where Year is 2021

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Number of items: 338.


Aeffner, Famke, Turner, Oliver and Sing, Tobias (2021) Special Issue on Digital Pathology, Tissue Image Analysis, Artificial Intelligence, and Machine Learning: Approximation of the Effect of Novel Technologies on Toxicologic Pathology. Toxicologic Pathology, Volume (4). pp. 705-708. ISSN 15331601

Aksenov, Sergey, Roberts, John, Ganesh, Mugundu, Thudium-Mueller, Karen, Bhattacharya, Indranil and Tortorici, Michael (2021) Rational prediction of human dose for gene therapy based on translational dose-response studies. Clinical Pharmacology & Therapeutics. ISSN 0009-92361532-6535

Alave Reyes-Furrer, Angela, De Andrade, Sonia, Bachmann, Domininc, Jeker, Heidi, Steinmann, Martin, Accart Gris, Nathalie, Dunbar, Andrew W., Rausch, Martin, Bono, Epifania, Rimann, Markus and Keller, Hansjoerg (2021) Matrigel 3D bioprinting of contractile human skeletal muscle models recapitulating exercise and pharmacological responses. Communications biology, 4. p. 1183. ISSN 2399-3642

Albanese, F, Mercatelli, D, Finetti, L, Lamonaca, G, Pizzi, S, Shimshek, Derya, Bernacchia, G and Morari, M (2021) Constitutive silencing of LRRK2 kinase activity leads to early glucocerebrosidase deregulation and late impairment of autophagy in vivo. Neurobiology of Disease, 159. ISSN 1095953X

Allam, Ahmed, Feuerriegel, Stefan, Rebhan, Michael and Krauthammer, Michael (2021) Analyzing patient trajectories with artificial intelligence. Journal of medical internet research, 23 (12). ISSN 1438-8871; 1439-4456

Anderka, Oliver, Graf, Tobias, Seisenberger, Christina, Wiedmann, Michael and Wohlrab, Stefanie (2021) Best practices on critical reagent characterization, qualification, and life cycle management for HCP immunoassays. Biotechnology and Bioengineering. ISSN 0006-35921097-0290

Auberson, Yves (2021) Reflections on 2018-2020. EFMC Yearbook, 2021. pp. 3-4.

Auberson, Yves, Benfatti, Fides, Jaeschke, Georg and Zumbrunn, Cornelia (2021) News from the DMCCB - Congress Report from the Virtual EFMC-ISMC 2021. Chimia, 75 (12). pp. 1048-1050. ISSN 0009-4293

Auberson, Yves and Missbach, Martin (2021) Perspectives and Opportunities in Medicinal Chemistry: A View from the Novartis Institute for BioMedical Research in Basel, Switzerland. Chimia., 75 (12). pp. 1091-1095. ISSN 0009-4293

Auld, Douglas, Jenkins, Jeremy and Concannon, John (2021) Cell size homeostasis is maintained by a circuitry involving a CDK4-determined target size that programs the cell size-dependent activation of p38. Developmental cell. ISSN 1878-1551

Axelsson, Erik, Ljungvall, I, Bhoumik, Priyasma, Conn, LB, Muren, E, Ohlsson, A, Ohlsen, LH, Engdahl, K, Hagman, R, Hanson, J, Kryvokhyzha, D, Pettersson, M, Grenet, Olivier, Moggs, Jonathan, Del Rio Espinola, Alberto, Epe, C, Taillon, B, Tawari, N, Mane, S, Hawkins, T, Hedhammar, A, Gruet, P, Haggstrom, J and Lindblah-Toh, Kerstin (2021) The genetic consequences of dog breed formation-Accumulation of deleterious genetic variation and fixation of mutations associated with myxomatous mitral valve disease in cavalier King Charles spaniels. PLoS genetics, 17 (9). e1009726. ISSN 1553-7404

Axford, Jake, Briner, Karin, Cheung, Atwood, Dales, Natalie, Hurley, Timothy, Jain, Monish, Sung, Moo, Manchester, John, Hamann, Lawrence, Chin, Donovan, Shin, Youngah and Sivasankaran, Rajeev (2021) Use of Intramolecular 1,5-sulfur-oxygen and 1,5-sulfur-halogen interactions in the design of N-methyl-5-aryl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine SMN2 splicing modulators. Journal of Medicinal Chemistry. ISSN 0022-26231520-4804


Babu, Charles, Phulera, Swastik, Hao, Qin, Wall, Daniel, Nettleton, David, Pathak, Tejas and Siuti, Piro (2021) Biosynthetic production and evaluation of knotted peptide topology and characteristics. ACS Omega, 6 (44). pp. 29555-29566. ISSN 2470-13432470-1343

Baczyk, Paulina, Wyss, Brigitte, Widmer, Jasmin, Hartmann, Steffen, Wassmann, Paul, Lobo, Susana, Jesus, Lídia , Gomes, Joana and Batista, Ana (2021) Stability liabilities of biotherapeutic proteins: early assessment as mitigation strategy. Journal of pharmaceutical and biomedical analysis, 192. pp. 1-15. ISSN 1873-264X; 0731-7085

Barabas, Amanda J, Soini, Helena A, Novotny, Milos V, Williams, David R, Desmond, Jacob A, Lucas, Jeffrey R, Erasmus, Marisa A, Cheng, Heng-Wei and Gaskill, Brianna N (2021) Compounds from plantar foot sweat, nesting material, and urine show strain patterns associated with agonistic and affiliative behaviors in group housed male mice, Mus musculus. PloS one, 16 (5). e0251416. ISSN 1932-6203

Barabas, Amanda J., Dijak, Stephanie R., Yatcilla, Jane F., Walker, Danielle N. and Gaskill, Brianna N. (2021) Modulating captive mammalian social behavior: a scoping review on olfactory treatments. Applied Animal Behaviour Science, 244. p. 105489. ISSN 01681591

Baran, Szczepan, Lim, Maria A., Do, Johnny P., Stolyar, Polina, Rabe, Mark D., Schaevitz, Laura R. and Cadena, Samuel (2021) Digital biomarkers enable automated, longitudinal monitoring in a mouse model of aging. The journals of gerontology. Series A, Biological sciences and medical sciences. ISSN 1758535X

Bartels, Christian and Dumortier, Thomas (2021) Inverse probability of censoring weighting for visual predictive checks of time-to-event models with time-varying covariates. Pharmaceutical Statistics. ISSN 1539-16041539-1612

Bartels, Christian, Jain, Monish, Yu, Jing, Tillmann, Hanns-Christian and Vaidya, Soniya (2021) Population Pharmacokinetic Analysis of Indacaterol/Glycopyrronium/Mometasone Furoate After Administration of Combination Therapies Using the Breezhaler® Device in Patients with Asthma. European Journal of Drug Metabolism and Pharmacokinetics, 46 (4). pp. 487-504. ISSN 21070180

Barth, Melanie, Bacioglu, Mehtap, Tanriöver, Gaye, Schwarz, Niklas, Novotny, Renata, Brandes, Janine, Welzer, Marc, Mazzitelli, Sonia, Häsler, Lisa, Schweighauser, Manuel, Kronenberg-Versteeg, Deborah, Fog, Karina, Ambjørn, Malene, Bousset, Luc, Melki, Ronald, Shimshek, Derya, Koch, Henner and Jucker, Mathias (2021) Microglial inclusions and neurofilament light chain release follow neuronal α-synuclein lesions in long-term brain slice cultures. Molecular Neurodegeneration, 16 (1). ISSN 17501326

Bashkar, Varun, Desogus, Jessica, Graff-Meyer, Alexandra, Schenk, Andreas, Cavadini, Simone and Chao, Jeffrey A (2021) Dynamic association of human Ebp1 with the ribosome. RNA (New York, N.Y.), 27 (4). pp. 411-419. ISSN 1469-9001

Bastien, Julie, Menon, Sue, Messa, Mirko and Nyfeler, Beat (2021) Molecular targets and approaches to restore autophagy and lysosomal capacity in neurodegenerative disorders. Molecular aspects of medicine, 82. p. 101018. ISSN 1872-9452

Bauer, Daniel, Buckley , Lorrene A. , Delafoy , Laure, Ellinger-Ziegelbauer , Heidrun, Fellows , Mick D. , Gerets , Helga H. J., Howe , Jonathan, Kaijser , Gerry , Nicolette , John, Pettersen , Betty A. and Schimpf , Brian (2021) A cross-industry survey on photosafety evaluation of pharmaceuticals after implementation of ICH S10. Regulatory toxicology and pharmacology : RTP, 125. p. 105017. ISSN 1096-0295

Bauer, Sebastian, Demetri, George, Jeay, Sebastien, Dummer, Reinhard , Guerreiro, Nelson, Tan, Daniel, Jullion, Astrid, Meille, Christophe, Ferretti, Stephane Raymond, Van Bree, Laurence, Halilovic, Ensar, Hourcade-Potelleret, Florence, Fabre, Claire, Wuerthner, Jens and Cassier, Philippe A. (2021) First-in-Human, Phase I Dose-Escalation Study of CGM097, a HDM2 Inhibitor in Adult Patients With p53 Wild-type Advanced Solid Malignancies. British journal of cancer : BJC, 125. pp. 687-698. ISSN 1532-1827

Bednarczyk, Dallas (2021) Passive influx and ion trapping are more relevant to the cellular accumulation of highly permeable low molecular weight acidic drugs than is Organic Anion Transporter 2 (OAT2). Drug metabolism and disposition: the biological fate of chemicals. ISSN 1521009X

Begum, Alaybeyoglu, Ho Wa, Cheng, Kshama, Doshi, Vishruti, Makani and Stein, Andrew (2021) Estimating drug potency in the competitive target mediated drug disposition (TMDD) system when the endogenous ligand is included. Journal of Pharmacokinetics and Pharmacodynamics, 48 (4). pp. 447-464. ISSN 15738744

Belcher, Bridget, Ward, Carl and Nomura, Daniel (2021) Ligandability of E3 Ligases for Targeted Protein Degradation Applications. Biochemistry. ISSN 1520-4995

Bellot, Muriel, Luetjens, C Marc, Bagger, Morten, Horvath, Courtney, Sutter, Esther, DeLise, Anthony, Brees, Dominique, Carballido, Jose, Pingili, Ratnakar, Ramanathan, Krishnan, Kieseier, Bernd and Hellwig, Kerstin (2021) Effect of ofatumumab on pregnancy, parturition, and lactation in cynomolgus monkeys. Reproductive toxicology (Elmsford, N.Y.), 108. pp. 28-34. ISSN 1873-1708

Bieberich, Andrew, Rajwa, Bartek, Irvine, Allison, Fatig, Raymond, Fekete, Alexander, Jin, Hong, Kutlina, Elena and Urban, Laszlo (2021) Acute Cell Stress Screen with Supervised Machine Learning in Association with in vitro Pharmacological Profiling Predicts Cytotoxicity of Excipients. Journal of Pharmacological and Toxicological Methods, e-pub. pp. 1-15.

Biering, Scott B., Van Dis, Erik, Yamashiro, Livia H., Nguyenla, Xammy , Wehri, Eddie, Dugast-Darzacq, Claire , Graham, Thomas G.W., Stroumza, Julian , Golovkine, Guillaume , Roberts, Allison W., Fines, Daniel M. , Fox, Douglas M., Ward, Carl, Spradlin, Jessica, Dovala, Dustin, Schaletzky, Julia and Stanley, Sarah A. (2021) Screening a Library of FDA-Approved and Bioactive Compounds for Antiviral Activity against SARS-CoV-2. ACS infectious diseases. ISSN 23738227

Bigaud, Marc, Rudolph, Bettina, Briard, Emmanuelle, Beerli, Christian, Hofmann, Andreas, Hermes, Erwin, Muellershausen, Florian, Schubart Wellensiek, Anna and Gardin, Anne (2021) Siponimod (BAF312) penetrates, distributes, and acts in the central nervous system: Preclinical insights. Multiple sclerosis journal - experimental, translational and clinical, 7 (4). p. 20552173211049168. ISSN 2055-2173

Bill, Anke, Espinola, Sheryll, Guthy, Daniel Alexander, Lu, Min, Marelli, Anthony, Mendiola, Angelica, Miraglia, Loren, Taylor, Brandon, Haling, Jake, Vargas, Leonardo, Orth, Anthony, King, Frederick and Lanter, Mylene (2021) EndoBind - Real-time detection of endogenous protein-protein interactions. Nature communications Biology.

Bleu, Melusine, Grass, Verena, Mermet-Meillon, Fanny Anne-Marie, Barys, Louise, Holzer, Laura, Marques Lopes, Rui, Barbosa, Ines, Delmas, Cecile, Hinniger, Alexandra, Chau, Suzanne, Kaufmann, Markus, Haenni, Simon, Berneiser, Karolin Fiona, Wahle, Maria, Moravec, Ivana, Vissieres, Alexandra, Poetsch, Tania, Ahrne, Erik, Carte, Nathalie, Voshol, Johannes, Fischer, Matteo, Stachyra, Therese-Marie, Freuler, Felix, Gutmann, Sascha, Fernandez, Cesar, Naumann, Ulrike, Roma, Guglielmo, Schuebeler, Dirk, Nieto-Oberhuber, Cristina, Cobos-Correa, Amanda, Ferretti, Stephane Raymond and Galli, Giorgio (2021) PAX8 and MECOM are interaction partners driving Ovarian Carcinogenesis. Nature communications, 12. p. 2442. ISSN 2041-1723

Bluemel, Oliver, Friess, Wolfgang, Bechtold-Peters, Karoline, Hoelzl, Georg, Hauptmann, Astrid and Buecheler, Jakob (2021) Scaling Down Large-Scale Thawing of Monoclonal Antibody Solutions: 3D Temperature Profiles, Changes in Concentration, and Density Gradients. Pharmaceutical research, 38 (11). pp. 1977-1989. ISSN 1573-904X

Bolje, Aljoša (2021) Project report (for Faculty of Pharmacy): Structural characterization of proteins in solid pharmaceutical forms. Project report published on the Faculty of Pharmacy's web page.

Booler, Helen, Lejeune, Typhaine, Sorden, Steve, Schafer, Kenneth, Short, Brian, Farman, Cindy, Ramos, Margaret, Bennett, Bindu, Krishna, Yekkala, Atzpodien, Elke-Astrid, Turner, Oliver, Brassard, Jaqueline, Gruebbel, Margarita and Foley, George (2021) Scientific and Regulatory Policy Committee Points to Consider*: Fixation, Trimming and Sectioning of Non-Rodent Eyes and Ocular Tissues for Examination in Ocular and General Toxicity Studies. Toxicologic pathology. ISSN 1533-1601; 0192-6233

Boyle, Molly, Bennet, Bindu, Houle, Christopher D., Sura, Radhakrishna, Colman, Karyn, Romeike, Annette, Frisk, Anna-Lena, Garcia, Begonya and Elmore, Susan A. (2021) Publication Categories in Toxicologic Pathology. Toxicologic Pathology. ISSN 15331601

Brase, Jan Christoph, Robert, Walter, Savchenko, Alexander, Gusenleitner, Daniel, Garrett, James, Schimming, Tobias , Varaljai, Renata, Castelletti, Deborah, Kim, Ju, Dakappagari, Naveen, Schultz Gonzaga, Kenneth, Robert, Caroline, Long, Georgina V, Nathan, Paul, Ribas, Antoni, Flaherty, Keith, Karaszewska, Boguslawa, Schachter, Jacob, Sucker, Antje, Schmid, Kurt W, Zimmer, Lisa, Livingstone, Elisabeth, Tan, Sartika, Schadendorf, Dirk and Roesch, Alexander (2021) Role of Tumor-Infiltrating B Cells in Clinical Outcome of Patients with Melanoma Treated With Dabrafenib Plus Trametinib. Clinical cancer research : an official journal of the American Association for Cancer Research. ISSN 15573265

Briggs, Katahrine, Camara, Tima, Diaz, Carlos, Drew, Phil, Drewe, Will, Kors, Jan, van Mulligen, Erik, Pognan, Francois, Quintana, Jordi Ramon, Sarntivijai, Sirarat and Steger-Hartmann, Thomas (2021) Guidelines for FAIR sharing of preclinical safety and off-target pharmacology data. ALTEX, 38 (2). pp. 187-197. ISSN 1868596X

Brightling, Christopher E, Kulkarni, Swarupa, Lambrecht, Bart, Sandham, David, Weiss, Markus and Altman, Pablo (2021) The pharmacology of the prostaglandin D2 receptor 2 (DP2) receptor antagonist, fevipiprant. Pulmonary Pharmacology and Therapeutics, 68. p. 102030. ISSN 15229629

Brogdon, Jennifer, Pruteanu-Malinici, Iulian, Melenhorst, J. Joseph, June, Carl H., Fraietta, Joseph A., Young, Regina M., Levine, Bruce L. and Lacey, Simon F. (2021) Decade-long Remissions of Leukemia Sustained by the Persistence of Activated CD4 CAR T Cells. Science translational medicine.

Bruin, Gerardus, Ball, Kathryn, Escandon, Enrique, Funk, Christoph, Pereira, Joao, Brady, Kevin, Yang, Tong_Yuan and Yu, Hongbin (2021) CHARACTERIZING THE PHARMACOKINETICS AND BIODISTRIBUTION OF THERAPEUTIC PROTEINS: AN INDUSTRY WHITE PAPER. Drug metabolism and disposition, 50. pp. 858-866.

Buechel, David, Sugiyama, Nami, Rubinstein, Natalia, Saxena, Meera, Kalathur, Ravi K R, Lüönd, Fabiana, Vafaizadeh, Vida, Valenta, Tomas, Hausmann, George, Cantù, Claudio, Basler, Konrad and Christofori, Gerhard (2021) Parsing β-catenin's cell adhesion and Wnt signaling functions in malignant mammary tumor progression. Proceedings of the National Academy of Sciences of the United States of America, 118 (34). ISSN 1091-6490


Campbell, John M. , Foti, Chris, Wang, Chloe, Adams, Neal, Allain, Leonardo R., Araujo, Gabriela, Azevedo, Renan , Ribeiro Franca, Juçara , Hicks, Simon R. , Hostyn, Steven , Jansen, Patrick J. , Kotoni, Dorina, Kuemmell, Andreas, Marden, Stacey , Rullo, Gregory, Santos, Ana Cláudia O. , Sluggett, Gregory W., Zelesky, Todd and Baertschi, Steven W. (2021) Assessing the Relevance of Solution Phase Stress Testing of Solid Dosage Form Drug Products: A Cross-Industry Benchmarking Study. Journal of Pharmaceutical Sciences. ISSN 15206017

Canham, Steve, Jenkins, Jeremy, Forrester, William, Hild, Marc, Ambrose, Jessi, Sigoillot, Frederic, Gleim, Scott, Cobos-Correa, Amanda, Wang, Ying, Eggimann, Fabian, Moore, Charles, Mapa, Felipa, Burks, Heather, Roma, Guglielmo, Krastel, Philipp, Tallarico, John, Nomura, Daniel, Fisher, David, Zhang, Lydia, Cho, Hyelim, Shen, Qiong, Okumura, Mikiko, Kawakami, Akinori, Miller, Howard, Dix, Ina and Ross, Nathan (2021) CYP27A1 dependent anti-melanoma activity of limonoid natural products targets mitochondrial metabolism. Cell chemical biology. ISSN 24519456

Carballido, Jose and Spits, Hergen (2021) Legends of allergy and immunology: Jan E. de Vries. Allergy. ISSN 13989995

Carbonneau, Seth, Sharma, Sujata, Peng, Liaomin, Rajan, Vaisakh, Hainzl, Dominik, Henault, Martin, Yang, Chian, Hale, Jacob, Shulok, Janine, Tallarico, John, Porter, Jeffrey, Brogdon, Jennifer, Dranoff, Glenn, Bradner, Jay, Hild, Marc and Guimaraes, Carla (2021) An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity. Cell Chemical Biology. ISSN 24519448

Carstensen, Saskia, Gress, Christina, Erpenbeck, Veit, Kazani, Shamsah, Hohlfeld, Jens, Sandham, David and Mueller, Meike (2021) Prostaglandin D2 metabolites activate asthmatic patient-derived type 2 innate lymphoid cells and eosinophils via the DP2 receptor. Respiratory research, 22 (1). p. 262. ISSN 1465-993X

Cassaro, A, Grillo, G, Esposito, I, Reda, G, Cairoli, R, Beghini, A, Notaro, M, Gliozzo, J, Trojani, A, Valentini, G and Di Camillo, B (2021) FZD6 triggers Wnt–signalling driven by WNT10BIVS1 expression and highlights new targets in T cell acute lymphoblastic leukemia. Hematological oncology. ISSN 1099-1069

Chen, Heller, Cui, Xiaoming, Pognan, Nathalie, Quinlan, Michelle, Kapoor, Shruti, Rahmanzadeh, Gholamreza, Giovannini, Monica and Marbury, Thomas (2021) Pharmacokinetics of capmatinib in participants with hepatic impairment: A phase 1, open-label, single-dose, parallel-group study. British Journal of Clinical Pharmacology. ISSN 13652125

Chen, Wentao, Luo, Jian, Ye , Yuan, Hoyle, Ryan, Liu, Wei, Borst, Rowie, Kazani, Shamsah, Shikatani, Eric, Erpenbeck, Veit, Pavord, Ian, Klenerman, Paul, Sandham, David and xue, luzheng (2021) Prostaglandin D2 drives tissue remodelling functions and prostaglandin D2 autocrine production in type 2 cytotoxic T cells. The journal of immunology, 206. pp. 2714-2724. ISSN 1550-6606

Chen, Xinhui, Cui, Xiaoming, Pognan, Nathalie, Quinlan, Michelle, Kapoor, Shruti, Rahmanzadeh, Gholamreza, Giovannini, Monica and Marbury, Thomas C (2021) Pharmacokinetics of capmatinib in participants with hepatic impairment: A phase 1, open-label, single-dose, parallel-group study. British journal of clinical pharmacology. ISSN 1365-2125

Chiang, Chih-Yuan, Zhong, Yang, Ward, Michael M, Lane, Douglas J, Kenny, Tara, Rosario-Acevedo, Raysa, Eaton, Brett P, Trevino, Sylvia R, Chance, Taylor B, Worsham, Patricia L, Waag, David M, Moore, Richard T, Cazares, Lisa H, Cote , Christopher K, Zhou, Yingyao and Panchal, Rekha G (2021) Proteomic Analysis of Non-human Primate Peripheral Blood Mononuclear Cells During Burkholderia mallei Infection Reveals a Role of Ezrin in Glanders Pathogenesis. Frontiers in Microbiology, 12. ISSN 1664302X

Christian, Lohasz, Loretan, Jacqueline, Goerlach, Ekkehard, Sterker, Dario, Kasper, Renggli, Paul, Argast, Olivier, Frey, Wiesmann, Marion, Wartmann, Markus, Rausch, Martin and Andreas, Hierlemann (2021) A Microphysiological Cell-Culturing System for Pharmacokinetic Drug Exposure and High-Resolution Imaging of Arrays of 3D Microtissues. Frontiers in pharmacology, 12. p. 785851. ISSN 1663-9812

Christler, Anna, Scharl, Theresa, Sauer, Dominik Georg, Koeppl, Johannes, Tscheließnig, Anne, Toy, Cabir, Melcher, Michael, Jungbauer, Alois and Dürauer, Astrid (2021) Technology transfer of a monitoring system to predict product concentration and purity of biopharmaceuticals in real‐time during chromatographic separation. Biotechnology and Bioengineering. pp. 1-12. ISSN 0006-3592

Christophe, Pellefigues, Karmella, Naidoo, Palak, Mehta, Alfonso , Schmidt, Ferdinand, Jagot, Roussel, Elsa, Cait, Alissa, Bibek, Yumnam, Sally, Chappell, Meijlink, Kimberly, Mali, Chamberis, Jean, Jiang, Gavin, Painter, Filbey, Kara, Uluckan, Ozge, Olivier, Gasser and Graham, LeGros (2021) Basophils promote barrier dysfunction and resolution in the atopic skin. Journal of Allergy and Clinical Immunology. ISSN 10976825

Colman, Karyn, Andrews, Rachel A, Atkins, Hannah, Boulineau, Theresa, Bradley, Alys, Braendli-Baiocco, Annamaria, Capobianco, Raffaella, Caudell, David, Cline, Mark, Doi, Takuya, Ernst, Rainer, Everitt, Jeffrey, Fant, Pierluigi, Gruebbel, Margarita, Mecklenberg, Lars, Miller, Andrew D, Nikula, Kristin, Satake, Shigeru, Schwartz, Julie, Shimoi, Akihito, Sobry, Cecile, Taylor, Ian, Van Esch, Eric, Vemireddi, Vimala, Vidal, Justin, Wood, Charles and Vahle, John (2021) International harmonization of nomenclature and diagnostic criteria (INHAND): Non-proliferative and proliferative lesions of the non-human primate (M. fascicularis). Journal of Toxicologic Pathology, 34. pp. 1-182. ISSN 09149198

Conlon, Kevin, Watson, Dionysios C, Waldmann, Thomas A, Valentin, Antonio, Bergamaschi, Cristina, Felber, Barbara K, Peer, Cody J, Figg, William D, Potter, E. Lake, Roederer, Mario, McNeel, Douglas G, Thompson, John A , Gupta, Sumati, Leidner, Rom, Wang-Gillam, Andrea, Parikh, Nehal, Long, Debby, Kurtulus-Aksoylar, Sema, Lee, Lang Ho, Roy Chowdhury, Niladri, Bender, Florent and Pavlakis, George N (2021) Phase I study of single agent NIZ985, a recombinant heterodimeric IL-15 agonist, in adult patients with metastatic or unresectable solid tumors. Journal for immunotherapy of cancer, 9 (11). ISSN 2051-1426

Corey, Kathleen E, Pitts, Rebecca, Lai, Michelle, Loureiro, Joe, Masia, Ricard, Osganian, Stephanie A, Gustafson, Jenna L, Hutter, Matthew M, Gee, Denise W, Meireles, Ozanan R, Witkowski, Elan R, Richards, Shola, Jacob, Jaison, Finkel, Nancy, Ngo, Debby, Wang, Thomas J, Gerszten, Robert E, Ukomadu, Chinweike and Jennings, Lori (2021) ADAMTSL2 protein and a soluble biomarker signature identify significant and advanced fibrosis in adults with NAFLD. Journal of hepatology. ISSN 1600-0641

Cremer, Malika, Rooks, Daniel, Fretault, Nathalie, Schubert-Tennigkeit, Agnes Annette and Papanicolaou, Dimitris (2021) Bimagrumab to Improve Recovery after Hip Fracture in the Elderly: A Randomised, Double-Blind, Placebo-Controlled Phase 2a/b Study. The Lancet Healthy Longevity, 2 (5). E263-E274.


Dawson King, Janet and Vogelsanger, Melanie (2021) Cantharidin-induced skin blister as an in vivo model of inflammation. Current Protocols in Pharmacology , 1 (e49). pp. 1-14.

De Maria, D, Fahrni, S, Ramrath, D, Lozac'H, Frederic, Marvalin, Cyrille and Synal, HA (2021) GAS MEASUREMENTS AT LEA Performance and analysis of labelled biomedical compounds. Annual report of ETH Zurich university.

Delgado, Pete, Glass, Raoul Julian, Geraci, Gina, Duvadie, Rohit, Majumdar, Dyuti, Robinson, Richard, Elmaarouf, Imran, Mikus, Malte and Tan, Kian (2021) Use of Green Solvents in Metallaphotoredox Cross-Electrophile Coupling Reactions Utilizing a Lipophilic Modified Dual Ir/Ni Catalyst System. Journal of Organic Chemistry, 86 (23). 17428-17436. ISSN 1520-6904

Di Marco, Fiammetta, Berger, Thomas, Esser-Skala, Wolfgang, Rapp, Erdmann, Regl, Christof and Huber, Christian (2021) Simultaneous Monitoring of Monoclonal Antibody Variants by Strong Cation-Exchange Chromatography Hyphenated to Mass Spectrometry to Assess Quality Attributes of Rituximab-Based Biotherapeutics. International journal of molecular sciences, 22 (16). ISSN 1422-0067

Di Nanni, Noemi, Reyes Quiroz, Alejandro, Ho, Daniel, Durand, Eric, de Weck, Antoine, Ihry, Robert and Kauffmann, Audrey (2021) TRAWLING: a Transcriptome Reference Aware of spLIciNG events. biorxiv.

Dickson, Callum, Hornak, Viktor and Duca, Jose (2021) Relative Binding Free-Energy Calculations at Lipid-Exposed Sites: Deciphering Hot Spots. Journal of chemical information and modeling. ISSN 1549-960X

Diener, John, Mowbray, Sarah, Huang, WaanJeng, Yowe, David, Xu, Jian, Caplan, Shari, Misra, Abhay, Kapur, Ankur, Shapiro, Jeffrey, Ke, Xiaoling, Wu, Xiaoping, Bose, Avirup, Panza, Darrell, Chen, Min, Beaulieu, Valerie and Gao, Jiaping (2021) FGF21 Normalizes Plasma Glucose in Mouse Models of Type 1 Diabetes and Insulin Receptor Dysfunction. bioRxiv. pp. 1-19. ISSN

Dispas, Amandine, Guillarme, Davy, Hubert, Philippe, Clarke, Adrian and Grand-Guillaume-Perrenoud, Alexandre (2021) Interlaboratory study of a Supercritical Fluid Chromatography method for the determination of pharmaceutical impurities: evaluation of multi-systems reproducibility. Journal of pharmaceutical and biomedical analysis, 203 (Articl). ISSN 07317085

Dittrich, Birger (2021) On modelling disordered crystal structures through restraints from molecule-in-cluster computations,and distinguishing static and dynamic disorder. IUCrJ, International Union of Crystallography Journal , 8. pp. 305-318. ISSN 2052-2525

Dodd, Stephanie (2021) Use of PBPK Modeling for Predicting Drug-Food Interactions: Successful prediction using a middle-out approach. AAPS PharmSci, 23 (12). ISSN 1550-7416/21/0000-0001/0

Dorgau, Birthe, Georgiou, Maria, Chaudhary, Alexander, Moya-Molina, Marina, Collin, Joseph, Queen , Rachel, Hilgen, Gerrit, Davies, Tracey, Hewitt, Philip, Schmitt, Michael, Kusterman, Stefan, Pognan, Francois, Steel, David, Sernagor, Evelyne, Armstrong, Lyle and Lako, Majlinda (2021) Human iPSC-derived retinal organoid model for in vitro toxicity screening. Toxicology letters, 350. ISSN 1879-3169; 0378-4274

Dovala, Dustin, Fischer, Christian and Trauner, Dirk (2021) De novo Design of SARS-CoV-2 Main Protease Inhibitors. De novo Design of SARS-CoV-2 Main Protease Inhibitors.

Duca, Maria, Gillingham, Dennis, Olsen, Christian Adam, Sbardella, Gianluca, Skaanderup, Philip, van der Stelt, Mario, Vauzeilles, Boris, Vazquez, Ollala and Auberson, Yves (2021) The Chemical Biology-Medicinal Chemistry continuum: EFMC's vision. ChemBioChem, 22.


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Iyer, Raman, Vesna, petrovska jovanovska, Sanchez-Felix, Manuel, Fabiani, Flavio, Harlacher, Cornelius, Huzjak, Tilen, Berginc, Katja and Jaklič, Miha (2021) Amorphous Solid Dispersions (ASDs) – “The influence of material properties, manufacturing processes and technologies in drug product development". Pharmaceutics Journal, 13(10) (10). pp. 1682-1696.


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Klejbor, I, Shimshek, Derya, Klimaszewska-Łata, J, Velasco-Estevez, M, Moryś, J, Karaszewski, B, Szutowicz, A and Rutkowska, A (2021) EBI2 is expressed in glial cells in multiple sclerosis lesions and its knock-out modulates remyelination in the cuprizone model. European Journal of Neuroscience. ISSN 0953-816X1460-9568

Kolbinger, Frank, Di Padova, Franco E., Huppertz, Christine, Kuiper, Torsten, Carballido, Jose, Calonder, Claudio, Vogel, Beate Elisabeth, Rondeau, Jean-Michel, Bruin, Gerardus, Deodhar, Atul, Hawkes, Jason, McInnes, Iain B., Ritchlin, Christopher T., Rosmarin, David, Schett, Georg and Häusermann, Peter (2021) Secukinumab for the treatment of psoriasis, psoriatic arthritis, and axial spondyloarthritis: Physical and pharmacological properties underlie the observed clinical efficacy and safety. Pharmacology and Therapeutics. ISSN 1879016X

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Krell, Christoph and Gallou, Fabrice (2021) Water waste from surfactant chemistry: risk or opportunity? Organic process research & development, 25.

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Kuemmel, Sherko, Campone, Mario, Loirat, Delphine, Lopez Lopez, Rafael, Beck, J.Thaddeus , De Laurentiis, Michelino, Im, Seock-Ah, Kim, Sung-Bae, Kwong, Ava, Steger, Guenther G, Adelantado, Esther Zamora, Duhoux, Francois P, Greil, Richard, Kuter, Irene, Lu, Yen-Shen, Tibau, Ariadna, Özgüroğlu, Mustafa, Scholz, Christian, Singer, Christian F. , Vega, Estela, Wimberger, Pauline, Zamagni, Claudio, Couillebault, Xuan-Mai, Fan, Liqiong, Guerreiro, Nelson, Mataraza, Jennifer, Sand Dejmek, Janna and Chan , Arlene (2021) A Randomized Phase II Study of Anti-CSF-1 Monoclonal Antibody Lacnotuzumab (MCS110) Combined with Gemcitabine and Carboplatin in Advanced Triple Negative Breast Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research. ISSN 1557-3265

Kuzman, Drago, Bunc, Marko, Reiter, Fritz, Boncina, Matjaz, Žagar, Lan and Ravnik , Miha (2021) Long-Term Stability Predictions of Therapeutic Monoclonal Antibodies in Solution Using Arrhenius Based Kinetics. Scientific reports, 11 (20534).

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Le Grand, Darren, Gosling, Martin, Baettig, Urs, Bahra, Parmjit, Bala, Kamlesh, Brocklehurst, Cara, Budd, Emma, Butler, Rebecca, Cheung, Atwood, Collingwood, Stephen, Cox, Brian, Danahay, Henry, Edwards, Lee, Everatt, Brian, Glaenzel, Ulrike, Hall, Edward, Hatto, Julia, Howsham, Catherine, Hughes, Glyn, King, Anna, Koehler, Julia, Kulkarni, Swarupa, Lightfoot, Megan, Nicholls, Ian Michael, Page, Christopher, Pergl-Wilson, Giles, Robinson, Richard, Rowlands, David, Steward, Oliver, Taylor, Roger, Tranter, Pamela, Wagner, Beatrix, Williams, Gareth, Wright, Penny and Sandham, David (2021) Discovery of Icenticaftor (QBW251), a Cystic Fibrosis Transmembrane Conductance Regulator Potentiator with Clinical Efficacy in Cystic Fibrosis and Chronic Obstructive Pulmonary Disease. Journal of Medicinal Chemistry, 64 (11). pp. 7241-7260. ISSN 0022-26231520-4804

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Lee, Jung Seok, Han, Patrick, Chaudhury, Rabib, Khan, Shihan, Bickerton, Sean, McHugh, Michael D, Park, Hyun Bong, Siefert, Alyssa L, Rea, Gerald, Carballido, Jose, Horwitz, David A, Criscione, Jason, Perica, Karlo, Samstein, Robert, Rageb, Ragy, Kim, Dongin and Fahmy, Tarek M (2021) Metabolic and immunomodulatory control of type 1 diabetes via orally delivered bile-acid-polymer nanocarriers of insulin or rapamycin. Nature Biomedical Engineering, 2021 (5). pp. 983-997.

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Litchfield, Marcus, Wuest, Melinda, Glubrecht, Daryl, Briard, Emmanuelle, Auberson, Yves, McMullen, Todd, Brindley, David and Wuest, Frank (2021) PET Imaging of Autotaxin in Thyroid and Breast Cancer Models using [18F]PRIMATX. Molecular pharmaceutics.

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Lu, Yasong, Yang, Shu, Ho, Yu-Yun and Ji, Yan (2021) Ribociclib Population Pharmacokinetics and Pharmacokinetic/Pharmacodynamic Analysis of Neutrophils in Cancer Patients. Journal of Clinical Pharmacology. ISSN 15524604

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Lüönd, Fabiana, Sugiyama, Nami, Bill, Ruben, Bornes, Laura, Hager, Carolina, Tang, Fengyuan, Santacroce, Natascha, Beisel, Christian, Ivanek, Robert, Bürglin, Thomas, Tiede, Stefanie, van Rheenen, Jacco and Christofori, Gerhard (2021) Distinct contributions of partial and full EMT to breast cancer malignancy. Developmental cell, 56 (23). 3203-3221.e11. ISSN 1878-1551

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Machauer, Rainer, Lueoend, Rainer Martin, Hurth, Konstanze, Veenstra, Siem, Rueeger, Heinrich, Voegtle, Markus, Tintelnot-Blomley, Marina, Rondeau, Jean-Michel, Jacobson, Laura, Laue, Grit, Beltz, Karen and Neumann, Ulf (2021) Discovery of Umibecestat (CNP520): A Potent, Selective and Efficacious β-Secretase (BACE1) Inhibitor for the Prevention of Alzheimer’s Disease. Journal of Medicinal Chemistry, 64 (20). pp. 15262-15279. ISSN 0022-26231520-4804

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Wang-Lakshman, Lydia, Mendonza, Anisha, Huber, Roland, Walles, Markus, He, Yan-Ling and Jarugula, Venkateswar (2021) Pharmacokinetics, Metabolism, and Excretion of Licogliflozin, a Dual Inhibitor of SGLT1/2, in Rats, Dogs, and Humans. Xenobiotica.

Wang-Lakshman, Lydia, Zhuang, Miao, Wang, Lai, Gu, Helen, Gu, Jessie, McNamara, Elizabeth, Walles, Markus, Woessner, Ralph, Camenisch, Gian P., Einolf, Heidi and Chen, Jin (2021) Evaluation of the Absorption, Metabolism, and Excretion of a Single Oral 1 mg Dose of Tropifexor in Healthy Male Subjects and the Concentration Dependency of Tropifexor Metabolism. Drug metabolism and disposition, 49 (7). pp. 548-562. ISSN 1521-009X

Wasserbacher, Helmut and Spindler, Martin (2021) Machine learning for financial forecasting, planning and analysis: recent developments and pitfalls. Digital Finance.

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Willemsen, Joschka, Hoyler, Thomas, Noir, Emma, Tessier, Clemence, Sarret, Sophie, Thorsen, Tara Nicole, Littlewood-Evans, Amanda, Zhang, Juan, Rush, James, Guerini, Danilo and Siegel, Richard (2021) TNF leads to mtDNA release and cGAS/STING-dependent interferon responses that support inflammatory arthritis. Cell reports, 37 (6). p. 109977. ISSN 2211-1247

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Wolf, Babette, Jeliazkova-Mecheva, Valentina, Del Rio Espinola, Alberto, Cochin de Billy, Benjamin, Boisclair, Julie, Walker, Dana, Flaherty, Meghan and Flandre, Thierry (2021) An afucosylated anti-CD32b monoclonal antibody induced platelet-mediated adverse events in human Fcg receptor transgenic mouse model and its potential human translatability. Toxicological sciences. ISSN 1096-0929; 1096-6080

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Wygant, Matthew and Kikuchi, Lena (2021) Reducing protein quantification bottlenecks by automating the Octet® HTX with a Hudson PlateCrane. Hudson Robotics Application Note.

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Xiong, Yuan, Donovan, Katherine A., Eleuteri, Nicholas A., Yue, Hong, Kirmani, Nadia, Nowak, Radoslaw P. and Fischer, Eric S. (2021) Chemo-proteomics exploration of HDAC degradability by small molecule degraders. Cell chemical biology, 28 (10). 1514-1527.e4. ISSN 2451-9448

Xu, Huilei, Hon, Claudia, Kaiser, Sergio, Serrano Fernandez, Pablo, Hartmann, Nicole, Yates, Denise, Healey, Margaret, Gusev, Arkady, Laramie, Jason, Kennedy, Scott, Marc, Philippe, Paul, Ridker, Obeidat, Maen, Beste, Michael, Svensson, Eric and Madar, Aviv (2021) Coronary artery disease polygenic risk score identifies patients at higher risk for recurrent cardiovascular events in the CANTOS Trial. Circulation: Genomics and Precision Medicine.


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Zhao, Kangming, Ge, Xiaobin, Zheng, Yu, Shen, Xiaodong, Shi, Lei, Gallou, Fabrice, Cortes-Clerget, Margery , Louis Regnier, Morgan , Parmentier, Michael, Ye, Ning and Wu, Bin (2021) Micelle enabled C(sp2)–C(sp3) cross-electrophile coupling in water via synergistic nickel and copper catalysis†. Chemical Communications, 57 (62). pp. 7629-7632. ISSN 1359-73451364-548X

Zhao, Yongmei, Tai Fang, Li, Shen, Tsai-wei, Houdhari, Sulbha, Talsania, Keyur, Chen, Jack, Shetty, Jyoti, Kriga, Yuliya, Tran, Bao, Zhu, Bin, Chen, Zhong, Chen, Wanqiu, Wang, Charles, Jaeger, Erich, Meerzaman, Daoud, Lu, Charles, Idler, Kenneth, Zheng, Yuanting, Shi, Leming, Petitjean, Virginie, Sultan, Marc, Hung, Tiffany, Eric, Peters, Drabek, Jiri, Vojta, Petr, Maestro, Roberta, Gasparotto, Daniela, Koks, Sulev, Reimann, Ene, Scherer, Andreas, Nordlund, Jessica, Liljedahl, Ulrika, Foox, Jonathan, Mason, Christopher, Xiao, Chunlin and Xiao, Wenming (2021) Whole genome and exome sequencing reference datasets from a multi-center and cross-platform benchmark study. Scientific data, 8 (1). p. 296. ISSN 2052-4463

Zhou, Lili , Miller, Caitlyn , Miraglia, Loren, Mendiola, Angelica, Mure, Ludovic S. , Panda, Satchidananda , Xiao, Changchun and Kay, Steve (2021) A genome-wide microRNA screen identifies the microRNA-183/96/182 cluster as a modulator of circadian rhythms. Proceedings of the National Academy of Sciences, 118 (1). ISSN 0027-84241091-6490

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This list was generated on Thu May 23 21:31:33 2024 UTC.