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Aeffner, Famke and Turner, Oliver and Sing, Tobias (2021) Special Issue on Digital Pathology, Tissue Image Analysis, Artificial Intelligence, and Machine Learning: Approximation of the Effect of Novel Technologies on Toxicologic Pathology. Toxicologic Pathology, Volume (4). pp. 705-708. ISSN 15331601

Aksenov, Sergey and Roberts, John and Ganesh, Mugundu and Thudium-Mueller, Karen and Bhattacharya, Indranil and Tortorici, Michael (2021) Rational prediction of human dose for gene therapy based on translational dose-response studies. Clinical Pharmacology & Therapeutics. ISSN 0009-92361532-6535

Alave Reyes-Furrer, Angela and De Andrade, Sonia and Bachmann, Domininc and Jeker, Heidi and Steinmann, Martin and Accart Gris, Nathalie and Dunbar, Andrew W. and Rausch, Martin and Bono, Epifania and Rimann, Markus and Keller, Hansjoerg (2021) Matrigel 3D bioprinting of contractile human skeletal muscle models recapitulating exercise and pharmacological responses. Communications biology, 4. p. 1183. ISSN 2399-3642

Albanese, F and Mercatelli, D and Finetti, L and Lamonaca, G and Pizzi, S and Shimshek, Derya and Bernacchia, G and Morari, M (2021) Constitutive silencing of LRRK2 kinase activity leads to early glucocerebrosidase deregulation and late impairment of autophagy in vivo. Neurobiology of Disease, 159. ISSN 1095953X

Allam, Ahmed and Feuerriegel, Stefan and Rebhan, Michael and Krauthammer, Michael (2021) Analyzing patient trajectories with artificial intelligence. Journal of medical internet research, 23 (12). ISSN 1438-8871; 1439-4456

Anderka, Oliver and Graf, Tobias and Seisenberger, Christina and Wiedmann, Michael and Wohlrab, Stefanie (2021) Best practices on critical reagent characterization, qualification, and life cycle management for HCP immunoassays. Biotechnology and Bioengineering. ISSN 0006-35921097-0290

Auberson, Yves (2021) Reflections on 2018-2020. EFMC Yearbook, 2021. pp. 3-4.

Auberson, Yves and Benfatti, Fides and Jaeschke, Georg and Zumbrunn, Cornelia (2021) News from the DMCCB - Congress Report from the Virtual EFMC-ISMC 2021. Chimia, 75 (12). pp. 1048-1050. ISSN 0009-4293

Auberson, Yves and Missbach, Martin (2021) Perspectives and Opportunities in Medicinal Chemistry: A View from the Novartis Institute for BioMedical Research in Basel, Switzerland. Chimia., 75 (12). pp. 1091-1095. ISSN 0009-4293

Auld, Douglas and Jenkins, Jeremy and Concannon, John (2021) Cell size homeostasis is maintained by a circuitry involving a CDK4-determined target size that programs the cell size-dependent activation of p38. Developmental cell. ISSN 1878-1551

Axelsson, Erik and Ljungvall, I and Bhoumik, Priyasma and Conn, LB and Muren, E and Ohlsson, A and Ohlsen, LH and Engdahl, K and Hagman, R and Hanson, J and Kryvokhyzha, D and Pettersson, M and Grenet, Olivier and Moggs, Jonathan and Del Rio Espinola, Alberto and Epe, C and Taillon, B and Tawari, N and Mane, S and Hawkins, T and Hedhammar, A and Gruet, P and Haggstrom, J and Lindblah-Toh, Kerstin (2021) The genetic consequences of dog breed formation-Accumulation of deleterious genetic variation and fixation of mutations associated with myxomatous mitral valve disease in cavalier King Charles spaniels. PLoS genetics, 17 (9). e1009726. ISSN 1553-7404

Axford, Jake and Briner, Karin and Cheung, Atwood and Dales, Natalie and Hurley, Timothy and Jain, Monish and Sung, Moo and Manchester, John and Hamann, Lawrence and Chin, Donovan and Shin, Youngah and Sivasankaran, Rajeev (2021) Use of Intramolecular 1,5-sulfur-oxygen and 1,5-sulfur-halogen interactions in the design of N-methyl-5-aryl-N-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine SMN2 splicing modulators. Journal of Medicinal Chemistry. ISSN 0022-26231520-4804


Babu, Charles and Phulera, Swastik and Hao, Qin and Wall, Daniel and Nettleton, David and Pathak, Tejas and Siuti, Piro (2021) Biosynthetic production and evaluation of knotted peptide topology and characteristics. ACS Omega, 6 (44). pp. 29555-29566. ISSN 2470-13432470-1343

Baczyk, Paulina and Wyss, Brigitte and Widmer, Jasmin and Hartmann, Steffen and Wassmann, Paul and Lobo, Susana and Jesus, Lídia and Gomes, Joana and Batista, Ana (2021) Stability liabilities of biotherapeutic proteins: early assessment as mitigation strategy. Journal of pharmaceutical and biomedical analysis, 192. pp. 1-15. ISSN 1873-264X; 0731-7085

Barabas, Amanda J and Soini, Helena A and Novotny, Milos V and Williams, David R and Desmond, Jacob A and Lucas, Jeffrey R and Erasmus, Marisa A and Cheng, Heng-Wei and Gaskill, Brianna N (2021) Compounds from plantar foot sweat, nesting material, and urine show strain patterns associated with agonistic and affiliative behaviors in group housed male mice, Mus musculus. PloS one, 16 (5). e0251416. ISSN 1932-6203

Barabas, Amanda J. and Dijak, Stephanie R. and Yatcilla, Jane F. and Walker, Danielle N. and Gaskill, Brianna N. (2021) Modulating captive mammalian social behavior: a scoping review on olfactory treatments. Applied Animal Behaviour Science, 244. p. 105489. ISSN 01681591

Baran, Szczepan and Lim, Maria A. and Do, Johnny P. and Stolyar, Polina and Rabe, Mark D. and Schaevitz, Laura R. and Cadena, Samuel (2021) Digital biomarkers enable automated, longitudinal monitoring in a mouse model of aging. The journals of gerontology. Series A, Biological sciences and medical sciences. ISSN 1758535X

Bartels, Christian and Dumortier, Thomas (2021) Inverse probability of censoring weighting for visual predictive checks of time-to-event models with time-varying covariates. Pharmaceutical Statistics. ISSN 1539-16041539-1612

Bartels, Christian and Jain, Monish and Yu, Jing and Tillmann, Hanns-Christian and Vaidya, Soniya (2021) Population Pharmacokinetic Analysis of Indacaterol/Glycopyrronium/Mometasone Furoate After Administration of Combination Therapies Using the Breezhaler® Device in Patients with Asthma. European Journal of Drug Metabolism and Pharmacokinetics, 46 (4). pp. 487-504. ISSN 21070180

Barth, Melanie and Bacioglu, Mehtap and Tanriöver, Gaye and Schwarz, Niklas and Novotny, Renata and Brandes, Janine and Welzer, Marc and Mazzitelli, Sonia and Häsler, Lisa and Schweighauser, Manuel and Kronenberg-Versteeg, Deborah and Fog, Karina and Ambjørn, Malene and Bousset, Luc and Melki, Ronald and Shimshek, Derya and Koch, Henner and Jucker, Mathias (2021) Microglial inclusions and neurofilament light chain release follow neuronal α-synuclein lesions in long-term brain slice cultures. Molecular Neurodegeneration, 16 (1). ISSN 17501326

Bashkar, Varun and Desogus, Jessica and Graff-Meyer, Alexandra and Schenk, Andreas and Cavadini, Simone and Chao, Jeffrey A (2021) Dynamic association of human Ebp1 with the ribosome. RNA (New York, N.Y.), 27 (4). pp. 411-419. ISSN 1469-9001

Bastien, Julie and Menon, Sue and Messa, Mirko and Nyfeler, Beat (2021) Molecular targets and approaches to restore autophagy and lysosomal capacity in neurodegenerative disorders. Molecular aspects of medicine, 82. p. 101018. ISSN 1872-9452

Bauer, Daniel and Buckley , Lorrene A. and Delafoy , Laure and Ellinger-Ziegelbauer , Heidrun and Fellows , Mick D. and Gerets , Helga H. J. and Howe , Jonathan and Kaijser , Gerry and Nicolette , John and Pettersen , Betty A. and Schimpf , Brian (2021) A cross-industry survey on photosafety evaluation of pharmaceuticals after implementation of ICH S10. Regulatory toxicology and pharmacology : RTP, 125. p. 105017. ISSN 1096-0295

Bauer, Sebastian and Demetri, George and Jeay, Sebastien and Dummer, Reinhard and Guerreiro, Nelson and Tan, Daniel and Jullion, Astrid and Meille, Christophe and Ferretti, Stephane Raymond and Van Bree, Laurence and Halilovic, Ensar and Hourcade-Potelleret, Florence and Fabre, Claire and Wuerthner, Jens and Cassier, Philippe A. (2021) First-in-Human, Phase I Dose-Escalation Study of CGM097, a HDM2 Inhibitor in Adult Patients With p53 Wild-type Advanced Solid Malignancies. British journal of cancer : BJC, 125. pp. 687-698. ISSN 1532-1827

Bednarczyk, Dallas (2021) Passive influx and ion trapping are more relevant to the cellular accumulation of highly permeable low molecular weight acidic drugs than is Organic Anion Transporter 2 (OAT2). Drug metabolism and disposition: the biological fate of chemicals. ISSN 1521009X

Begum, Alaybeyoglu and Ho Wa, Cheng and Kshama, Doshi and Vishruti, Makani and Stein, Andrew (2021) Estimating drug potency in the competitive target mediated drug disposition (TMDD) system when the endogenous ligand is included. Journal of Pharmacokinetics and Pharmacodynamics, 48 (4). pp. 447-464. ISSN 15738744

Belcher, Bridget and Ward, Carl and Nomura, Daniel (2021) Ligandability of E3 Ligases for Targeted Protein Degradation Applications. Biochemistry. ISSN 1520-4995

Bellot, Muriel and Luetjens, C Marc and Bagger, Morten and Horvath, Courtney and Sutter, Esther and DeLise, Anthony and Brees, Dominique and Carballido, Jose and Pingili, Ratnakar and Ramanathan, Krishnan and Kieseier, Bernd and Hellwig, Kerstin (2021) Effect of ofatumumab on pregnancy, parturition, and lactation in cynomolgus monkeys. Reproductive toxicology (Elmsford, N.Y.), 108. pp. 28-34. ISSN 1873-1708

Bieberich, Andrew and Rajwa, Bartek and Irvine, Allison and Fatig, Raymond and Fekete, Alexander and Jin, Hong and Kutlina, Elena and Urban, Laszlo (2021) Acute Cell Stress Screen with Supervised Machine Learning in Association with in vitro Pharmacological Profiling Predicts Cytotoxicity of Excipients. Journal of Pharmacological and Toxicological Methods, e-pub. pp. 1-15.

Biering, Scott B. and Van Dis, Erik and Yamashiro, Livia H. and Nguyenla, Xammy and Wehri, Eddie and Dugast-Darzacq, Claire and Graham, Thomas G.W. and Stroumza, Julian and Golovkine, Guillaume and Roberts, Allison W. and Fines, Daniel M. and Fox, Douglas M. and Ward, Carl and Spradlin, Jessica and Dovala, Dustin and Schaletzky, Julia and Stanley, Sarah A. (2021) Screening a Library of FDA-Approved and Bioactive Compounds for Antiviral Activity against SARS-CoV-2. ACS infectious diseases. ISSN 23738227

Bigaud, Marc and Rudolph, Bettina and Briard, Emmanuelle and Beerli, Christian and Hofmann, Andreas and Hermes, Erwin and Muellershausen, Florian and Schubart Wellensiek, Anna and Gardin, Anne (2021) Siponimod (BAF312) penetrates, distributes, and acts in the central nervous system: Preclinical insights. Multiple sclerosis journal - experimental, translational and clinical, 7 (4). p. 20552173211049168. ISSN 2055-2173

Bill, Anke and Espinola, Sheryll and Guthy, Daniel Alexander and Lu, Min and Marelli, Anthony and Mendiola, Angelica and Miraglia, Loren and Taylor, Brandon and Haling, Jake and Vargas, Leonardo and Orth, Anthony and King, Frederick and Lanter, Mylene (2021) EndoBind - Real-time detection of endogenous protein-protein interactions. Nature communications Biology.

Bleu, Melusine and Grass, Verena and Mermet-Meillon, Fanny Anne-Marie and Barys, Louise and Holzer, Laura and Marques Lopes, Rui and Barbosa, Ines and Delmas, Cecile and Hinniger, Alexandra and Chau, Suzanne and Kaufmann, Markus and Haenni, Simon and Berneiser, Karolin Fiona and Wahle, Maria and Moravec, Ivana and Vissieres, Alexandra and Poetsch, Tania and Ahrne, Erik and Carte, Nathalie and Voshol, Johannes and Fischer, Matteo and Stachyra, Therese-Marie and Freuler, Felix and Gutmann, Sascha and Fernandez, Cesar and Naumann, Ulrike and Roma, Guglielmo and Schuebeler, Dirk and Nieto-Oberhuber, Cristina and Cobos-Correa, Amanda and Ferretti, Stephane Raymond and Galli, Giorgio (2021) PAX8 and MECOM are interaction partners driving Ovarian Carcinogenesis. Nature communications, 12. p. 2442. ISSN 2041-1723

Bluemel, Oliver and Friess, Wolfgang and Bechtold-Peters, Karoline and Hoelzl, Georg and Hauptmann, Astrid and Buecheler, Jakob (2021) Scaling Down Large-Scale Thawing of Monoclonal Antibody Solutions: 3D Temperature Profiles, Changes in Concentration, and Density Gradients. Pharmaceutical research, 38 (11). pp. 1977-1989. ISSN 1573-904X

Bolje, Aljoša (2021) Project report (for Faculty of Pharmacy): Structural characterization of proteins in solid pharmaceutical forms. Project report published on the Faculty of Pharmacy's web page.

Booler, Helen and Lejeune, Typhaine and Sorden, Steve and Schafer, Kenneth and Short, Brian and Farman, Cindy and Ramos, Margaret and Bennett, Bindu and Krishna, Yekkala and Atzpodien, Elke-Astrid and Turner, Oliver and Brassard, Jaqueline and Gruebbel, Margarita and Foley, George (2021) Scientific and Regulatory Policy Committee Points to Consider*: Fixation, Trimming and Sectioning of Non-Rodent Eyes and Ocular Tissues for Examination in Ocular and General Toxicity Studies. Toxicologic pathology. ISSN 1533-1601; 0192-6233

Boyle, Molly and Bennet, Bindu and Houle, Christopher D. and Sura, Radhakrishna and Colman, Karyn and Romeike, Annette and Frisk, Anna-Lena and Garcia, Begonya and Elmore, Susan A. (2021) Publication Categories in Toxicologic Pathology. Toxicologic Pathology. ISSN 15331601

Brase, Jan Christoph and Robert, Walter and Savchenko, Alexander and Gusenleitner, Daniel and Garrett, James and Schimming, Tobias and Varaljai, Renata and Castelletti, Deborah and Kim, Ju and Dakappagari, Naveen and Schultz Gonzaga, Kenneth and Robert, Caroline and Long, Georgina V and Nathan, Paul and Ribas, Antoni and Flaherty, Keith and Karaszewska, Boguslawa and Schachter, Jacob and Sucker, Antje and Schmid, Kurt W and Zimmer, Lisa and Livingstone, Elisabeth and Tan, Sartika and Schadendorf, Dirk and Roesch, Alexander (2021) Role of Tumor-Infiltrating B Cells in Clinical Outcome of Patients with Melanoma Treated With Dabrafenib Plus Trametinib. Clinical cancer research : an official journal of the American Association for Cancer Research. ISSN 15573265

Briggs, Katahrine and Camara, Tima and Diaz, Carlos and Drew, Phil and Drewe, Will and Kors, Jan and van Mulligen, Erik and Pognan, Francois and Quintana, Jordi Ramon and Sarntivijai, Sirarat and Steger-Hartmann, Thomas (2021) Guidelines for FAIR sharing of preclinical safety and off-target pharmacology data. ALTEX, 38 (2). pp. 187-197. ISSN 1868596X

Brightling, Christopher E and Kulkarni, Swarupa and Lambrecht, Bart and Sandham, David and Weiss, Markus and Altman, Pablo (2021) The pharmacology of the prostaglandin D2 receptor 2 (DP2) receptor antagonist, fevipiprant. Pulmonary Pharmacology and Therapeutics, 68. p. 102030. ISSN 15229629

Brogdon, Jennifer and Pruteanu-Malinici, Iulian and Melenhorst, J. Joseph and June, Carl H. and Fraietta, Joseph A. and Young, Regina M. and Levine, Bruce L. and Lacey, Simon F. (2021) Decade-long Remissions of Leukemia Sustained by the Persistence of Activated CD4 CAR T Cells. Science translational medicine.

Buechel, David and Sugiyama, Nami and Rubinstein, Natalia and Saxena, Meera and Kalathur, Ravi K R and Lüönd, Fabiana and Vafaizadeh, Vida and Valenta, Tomas and Hausmann, George and Cantù, Claudio and Basler, Konrad and Christofori, Gerhard (2021) Parsing β-catenin's cell adhesion and Wnt signaling functions in malignant mammary tumor progression. Proceedings of the National Academy of Sciences of the United States of America, 118 (34). ISSN 1091-6490


Campbell, John M. and Foti, Chris and Wang, Chloe and Adams, Neal and Allain, Leonardo R. and Araujo, Gabriela and Azevedo, Renan and Ribeiro Franca, Juçara and Hicks, Simon R. and Hostyn, Steven and Jansen, Patrick J. and Kotoni, Dorina and Kuemmell, Andreas and Marden, Stacey and Rullo, Gregory and Santos, Ana Cláudia O. and Sluggett, Gregory W. and Zelesky, Todd and Baertschi, Steven W. (2021) Assessing the Relevance of Solution Phase Stress Testing of Solid Dosage Form Drug Products: A Cross-Industry Benchmarking Study. Journal of Pharmaceutical Sciences. ISSN 15206017

Canham, Steve and Jenkins, Jeremy and Forrester, William and Hild, Marc and Ambrose, Jessi and Sigoillot, Frederic and Gleim, Scott and Cobos-Correa, Amanda and Wang, Ying and Eggimann, Fabian and Moore, Charles and Mapa, Felipa and Burks, Heather and Roma, Guglielmo and Krastel, Philipp and Tallarico, John and Nomura, Daniel and Fisher, David and Zhang, Lydia and Cho, Hyelim and Shen, Qiong and Okumura, Mikiko and Kawakami, Akinori and Miller, Howard and Dix, Ina and Ross, Nathan (2021) CYP27A1 dependent anti-melanoma activity of limonoid natural products targets mitochondrial metabolism. Cell chemical biology. ISSN 24519456

Carballido, Jose and Spits, Hergen (2021) Legends of allergy and immunology: Jan E. de Vries. Allergy. ISSN 13989995

Carbonneau, Seth and Sharma, Sujata and Peng, Liaomin and Rajan, Vaisakh and Hainzl, Dominik and Henault, Martin and Yang, Chian and Hale, Jacob and Shulok, Janine and Tallarico, John and Porter, Jeffrey and Brogdon, Jennifer and Dranoff, Glenn and Bradner, Jay and Hild, Marc and Guimaraes, Carla (2021) An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity. Cell Chemical Biology. ISSN 24519448

Carstensen, Saskia and Gress, Christina and Erpenbeck, Veit and Kazani, Shamsah and Hohlfeld, Jens and Sandham, David and Mueller, Meike (2021) Prostaglandin D2 metabolites activate asthmatic patient-derived type 2 innate lymphoid cells and eosinophils via the DP2 receptor. Respiratory research, 22 (1). p. 262. ISSN 1465-993X

Cassaro, A and Grillo, G and Esposito, I and Reda, G and Cairoli, R and Beghini, A and Notaro, M and Gliozzo, J and Trojani, A and Valentini, G and Di Camillo, B (2021) FZD6 triggers Wnt–signalling driven by WNT10BIVS1 expression and highlights new targets in T cell acute lymphoblastic leukemia. Hematological oncology. ISSN 1099-1069

Chen, Heller and Cui, Xiaoming and Pognan, Nathalie and Quinlan, Michelle and Kapoor, Shruti and Rahmanzadeh, Gholamreza and Giovannini, Monica and Marbury, Thomas (2021) Pharmacokinetics of capmatinib in participants with hepatic impairment: A phase 1, open-label, single-dose, parallel-group study. British Journal of Clinical Pharmacology. ISSN 13652125

Chen, Wentao and Luo, Jian and Ye , Yuan and Hoyle, Ryan and Liu, Wei and Borst, Rowie and Kazani, Shamsah and Shikatani, Eric and Erpenbeck, Veit and Pavord, Ian and Klenerman, Paul and Sandham, David and xue, luzheng (2021) Prostaglandin D2 drives tissue remodelling functions and prostaglandin D2 autocrine production in type 2 cytotoxic T cells. The journal of immunology, 206. pp. 2714-2724. ISSN 1550-6606

Chen, Xinhui and Cui, Xiaoming and Pognan, Nathalie and Quinlan, Michelle and Kapoor, Shruti and Rahmanzadeh, Gholamreza and Giovannini, Monica and Marbury, Thomas C (2021) Pharmacokinetics of capmatinib in participants with hepatic impairment: A phase 1, open-label, single-dose, parallel-group study. British journal of clinical pharmacology. ISSN 1365-2125

Chiang, Chih-Yuan and Zhong, Yang and Ward, Michael M and Lane, Douglas J and Kenny, Tara and Rosario-Acevedo, Raysa and Eaton, Brett P and Trevino, Sylvia R and Chance, Taylor B and Worsham, Patricia L and Waag, David M and Moore, Richard T and Cazares, Lisa H and Cote , Christopher K and Zhou, Yingyao and Panchal, Rekha G (2021) Proteomic Analysis of Non-human Primate Peripheral Blood Mononuclear Cells During Burkholderia mallei Infection Reveals a Role of Ezrin in Glanders Pathogenesis. Frontiers in Microbiology, 12. ISSN 1664302X

Christian, Lohasz and Loretan, Jacqueline and Goerlach, Ekkehard and Sterker, Dario and Kasper, Renggli and Paul, Argast and Olivier, Frey and Wiesmann, Marion and Wartmann, Markus and Rausch, Martin and Andreas, Hierlemann (2021) A Microphysiological Cell-Culturing System for Pharmacokinetic Drug Exposure and High-Resolution Imaging of Arrays of 3D Microtissues. Frontiers in pharmacology, 12. p. 785851. ISSN 1663-9812

Christler, Anna and Scharl, Theresa and Sauer, Dominik Georg and Koeppl, Johannes and Tscheließnig, Anne and Toy, Cabir and Melcher, Michael and Jungbauer, Alois and Dürauer, Astrid (2021) Technology transfer of a monitoring system to predict product concentration and purity of biopharmaceuticals in real‐time during chromatographic separation. Biotechnology and Bioengineering. pp. 1-12. ISSN 0006-3592

Christophe, Pellefigues and Karmella, Naidoo and Palak, Mehta and Alfonso , Schmidt and Ferdinand, Jagot and Roussel, Elsa and Cait, Alissa and Bibek, Yumnam and Sally, Chappell and Meijlink, Kimberly and Mali, Chamberis and Jean, Jiang and Gavin, Painter and Filbey, Kara and Uluckan, Ozge and Olivier, Gasser and Graham, LeGros (2021) Basophils promote barrier dysfunction and resolution in the atopic skin. Journal of Allergy and Clinical Immunology. ISSN 10976825

Colman, Karyn and Andrews, Rachel A and Atkins, Hannah and Boulineau, Theresa and Bradley, Alys and Braendli-Baiocco, Annamaria and Capobianco, Raffaella and Caudell, David and Cline, Mark and Doi, Takuya and Ernst, Rainer and Everitt, Jeffrey and Fant, Pierluigi and Gruebbel, Margarita and Mecklenberg, Lars and Miller, Andrew D and Nikula, Kristin and Satake, Shigeru and Schwartz, Julie and Shimoi, Akihito and Sobry, Cecile and Taylor, Ian and Van Esch, Eric and Vemireddi, Vimala and Vidal, Justin and Wood, Charles and Vahle, John (2021) International harmonization of nomenclature and diagnostic criteria (INHAND): Non-proliferative and proliferative lesions of the non-human primate (M. fascicularis). Journal of Toxicologic Pathology, 34. pp. 1-182. ISSN 09149198

Conlon, Kevin and Watson, Dionysios C and Waldmann, Thomas A and Valentin, Antonio and Bergamaschi, Cristina and Felber, Barbara K and Peer, Cody J and Figg, William D and Potter, E. Lake and Roederer, Mario and McNeel, Douglas G and Thompson, John A and Gupta, Sumati and Leidner, Rom and Wang-Gillam, Andrea and Parikh, Nehal and Long, Debby and Kurtulus-Aksoylar, Sema and Lee, Lang Ho and Roy Chowdhury, Niladri and Bender, Florent and Pavlakis, George N (2021) Phase I study of single agent NIZ985, a recombinant heterodimeric IL-15 agonist, in adult patients with metastatic or unresectable solid tumors. Journal for immunotherapy of cancer, 9 (11). ISSN 2051-1426

Corey, Kathleen E and Pitts, Rebecca and Lai, Michelle and Loureiro, Joe and Masia, Ricard and Osganian, Stephanie A and Gustafson, Jenna L and Hutter, Matthew M and Gee, Denise W and Meireles, Ozanan R and Witkowski, Elan R and Richards, Shola and Jacob, Jaison and Finkel, Nancy and Ngo, Debby and Wang, Thomas J and Gerszten, Robert E and Ukomadu, Chinweike and Jennings, Lori (2021) ADAMTSL2 protein and a soluble biomarker signature identify significant and advanced fibrosis in adults with NAFLD. Journal of hepatology. ISSN 1600-0641

Cremer, Malika and Rooks, Daniel and Fretault, Nathalie and Schubert-Tennigkeit, Agnes Annette and Papanicolaou, Dimitris (2021) Bimagrumab to Improve Recovery after Hip Fracture in the Elderly: A Randomised, Double-Blind, Placebo-Controlled Phase 2a/b Study. The Lancet Healthy Longevity, 2 (5). E263-E274.


Dawson King, Janet and Vogelsanger, Melanie (2021) Cantharidin-induced skin blister as an in vivo model of inflammation. Current Protocols in Pharmacology , 1 (e49). pp. 1-14.

De Maria, D and Fahrni, S and Ramrath, D and Lozac'H, Frederic and Marvalin, Cyrille and Synal, HA (2021) GAS MEASUREMENTS AT LEA Performance and analysis of labelled biomedical compounds. Annual report of ETH Zurich university.

Delgado, Pete and Glass, Raoul Julian and Geraci, Gina and Duvadie, Rohit and Majumdar, Dyuti and Robinson, Richard and Elmaarouf, Imran and Mikus, Malte and Tan, Kian (2021) Use of Green Solvents in Metallaphotoredox Cross-Electrophile Coupling Reactions Utilizing a Lipophilic Modified Dual Ir/Ni Catalyst System. Journal of Organic Chemistry, 86 (23). 17428-17436. ISSN 1520-6904

Di Marco, Fiammetta and Berger, Thomas and Esser-Skala, Wolfgang and Rapp, Erdmann and Regl, Christof and Huber, Christian (2021) Simultaneous Monitoring of Monoclonal Antibody Variants by Strong Cation-Exchange Chromatography Hyphenated to Mass Spectrometry to Assess Quality Attributes of Rituximab-Based Biotherapeutics. International journal of molecular sciences, 22 (16). ISSN 1422-0067

Di Nanni, Noemi and Reyes Quiroz, Alejandro and Ho, Daniel and Durand, Eric and de Weck, Antoine and Ihry, Robert and Kauffmann, Audrey (2021) TRAWLING: a Transcriptome Reference Aware of spLIciNG events. biorxiv.

Dickson, Callum and Hornak, Viktor and Duca, Jose (2021) Relative Binding Free-Energy Calculations at Lipid-Exposed Sites: Deciphering Hot Spots. Journal of chemical information and modeling. ISSN 1549-960X

Diener, John and Mowbray, Sarah and Huang, WaanJeng and Yowe, David and Xu, Jian and Caplan, Shari and Misra, Abhay and Kapur, Ankur and Shapiro, Jeffrey and Ke, Xiaoling and Wu, Xiaoping and Bose, Avirup and Panza, Darrell and Chen, Min and Beaulieu, Valerie and Gao, Jiaping (2021) FGF21 Normalizes Plasma Glucose in Mouse Models of Type 1 Diabetes and Insulin Receptor Dysfunction. bioRxiv. pp. 1-19. ISSN

Dispas, Amandine and Guillarme, Davy and Hubert, Philippe and Clarke, Adrian and Grand-Guillaume-Perrenoud, Alexandre (2021) Interlaboratory study of a Supercritical Fluid Chromatography method for the determination of pharmaceutical impurities: evaluation of multi-systems reproducibility. Journal of pharmaceutical and biomedical analysis, 203 (Articl). ISSN 07317085

Dittrich, Birger (2021) On modelling disordered crystal structures through restraints from molecule-in-cluster computations,and distinguishing static and dynamic disorder. IUCrJ, International Union of Crystallography Journal , 8. pp. 305-318. ISSN 2052-2525

Dodd, Stephanie (2021) Use of PBPK Modeling for Predicting Drug-Food Interactions: Successful prediction using a middle-out approach. AAPS PharmSci, 23 (12). ISSN 1550-7416/21/0000-0001/0

Dorgau, Birthe and Georgiou, Maria and Chaudhary, Alexander and Moya-Molina, Marina and Collin, Joseph and Queen , Rachel and Hilgen, Gerrit and Davies, Tracey and Hewitt, Philip and Schmitt, Michael and Kusterman, Stefan and Pognan, Francois and Steel, David and Sernagor, Evelyne and Armstrong, Lyle and Lako, Majlinda (2021) Human iPSC-derived retinal organoid model for in vitro toxicity screening. Toxicology letters, 350. ISSN 1879-3169; 0378-4274

Dovala, Dustin and Fischer, Christian and Trauner, Dirk (2021) De novo Design of SARS-CoV-2 Main Protease Inhibitors. De novo Design of SARS-CoV-2 Main Protease Inhibitors.

Duca, Maria and Gillingham, Dennis and Olsen, Christian Adam and Sbardella, Gianluca and Skaanderup, Philip and van der Stelt, Mario and Vauzeilles, Boris and Vazquez, Ollala and Auberson, Yves (2021) The Chemical Biology-Medicinal Chemistry continuum: EFMC's vision. ChemBioChem, 22.


Elo, Petri and Li, Xiang-Guo and Liljenbäck, Heidi and Gardberg, Maria and Moisio, Olli and Miner, Maxwell and Virta, Jenni and Saraste, Antti and Srinivasarao, Madduri and Pugh, Michael and Low, Philip and Knuuti, Juhani and Jalkanen, Sirpa and Airas, Laura and Lu, June and Roivainen, Anne (2021) Efficacy and tolerability of a folic acid derivative of aminopterin in a rat focal model of multiple sclerosis. J Neuroinflammation, 18 (30).

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Krantz, Carsten (2021) Review of the Technical, Toxicological, and PKPD Considerations for Conducting Inhalation Toxicity Studies on Biologic Pharmaceuticals—The Outcome of a Cross-Industry Working Group Survey. Toxicologic Pathology. ISSN 15331601

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Kuzman, Drago and Bunc, Marko and Reiter, Fritz and Boncina, Matjaz and Žagar, Lan and Ravnik , Miha (2021) Long-Term Stability Predictions of Therapeutic Monoclonal Antibodies in Solution Using Arrhenius Based Kinetics. Scientific reports, 11 (20534).

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Le Grand, Darren and Gosling, Martin and Baettig, Urs and Bahra, Parmjit and Bala, Kamlesh and Brocklehurst, Cara and Budd, Emma and Butler, Rebecca and Cheung, Atwood and Collingwood, Stephen and Cox, Brian and Danahay, Henry and Edwards, Lee and Everatt, Brian and Glaenzel, Ulrike and Hall, Edward and Hatto, Julia and Howsham, Catherine and Hughes, Glyn and King, Anna and Koehler, Julia and Kulkarni, Swarupa and Lightfoot, Megan and Nicholls, Ian Michael and Page, Christopher and Pergl-Wilson, Giles and Robinson, Richard and Rowlands, David and Steward, Oliver and Taylor, Roger and Tranter, Pamela and Wagner, Beatrix and Williams, Gareth and Wright, Penny and Sandham, David (2021) Discovery of Icenticaftor (QBW251), a Cystic Fibrosis Transmembrane Conductance Regulator Potentiator with Clinical Efficacy in Cystic Fibrosis and Chronic Obstructive Pulmonary Disease. Journal of Medicinal Chemistry, 64 (11). pp. 7241-7260. ISSN 0022-26231520-4804

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Lee, Jung Seok and Han, Patrick and Chaudhury, Rabib and Khan, Shihan and Bickerton, Sean and McHugh, Michael D and Park, Hyun Bong and Siefert, Alyssa L and Rea, Gerald and Carballido, Jose and Horwitz, David A and Criscione, Jason and Perica, Karlo and Samstein, Robert and Rageb, Ragy and Kim, Dongin and Fahmy, Tarek M (2021) Metabolic and immunomodulatory control of type 1 diabetes via orally delivered bile-acid-polymer nanocarriers of insulin or rapamycin. Nature Biomedical Engineering, 2021 (5). pp. 983-997.

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Lewis, Richard (2021) Best practices for repurposing studies. Journal of computer-aided molecular design, 36 (1). pp. 1-5. ISSN 1573-4951

Li, Wenkui and Glick, Jim and Hatsis, Panagiotis and Fu, Yunlin and Chin, Harvey and Moench, Paul and Flarakos, Jimmy (2021) An integrated outsourcing practice of nonclinical LC-MS bioanalysis and toxicokinetics at Novartis small molecule drug development. Bioanalysis, 13 (12). pp. 1001-1010. ISSN 17576199

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Litchfield, Marcus and Wuest, Melinda and Glubrecht, Daryl and Briard, Emmanuelle and Auberson, Yves and McMullen, Todd and Brindley, David and Wuest, Frank (2021) PET Imaging of Autotaxin in Thyroid and Breast Cancer Models using [18F]PRIMATX. Molecular pharmaceutics.

Liu, Chen and Lu, Henry and Wang, Hongyun and Loo, Alice and Zhang, Xiamei and Yang, Guizhi and Kowal, Colleen and Delach, Scott and Wang, Ye and Goldoni, Silvia and Hastings, Bill and Wong , Karrie and Gao, Hui and Meyer, Matthew and Moody, Susan and LaMarche, Matthew and Engelman, Jeffrey and Williams, Juliet and Hammerman, Peter and Abrams, Tinya and Mohseni, Morvarid and Caponigro, Giordano and Hao, Huaixiang (2021) Combinations with allosteric SHP2 inhibitor TNO155 to block receptor tyrosine kinase signaling. Clinical Cancer Research, 27 (1). pp. 342-354. ISSN 15573265

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Lopez, John and G. de la Torre1, Beatriz and Albericio, Fernando and Ramkisson, Shaveer (2021) Refractive Index: The Ultimate Tool for Real-Time Monitoring of Solid-Phase Peptide Synthesis. Greening the Process. Organic Process Research & Development, 25 (https:). pp. 1047-1053. ISSN 1520-586X.

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Luo, Mai and Spradlin, Jessica and Boike, Lydia and Tong, Bingqi and Brittain, Scott and McKenna, Jeffrey and Tallarico, John and Schirle, Markus and Maimone, Thomas and Nomura, Dan (2021) Chemoproteomics-Enabled Ligand Screening Yields Covalent RNF114-Based Degraders that Mimics Natural Product Function. Cell chemical biology. ISSN 24519456

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Lüönd, Fabiana and Sugiyama, Nami and Bill, Ruben and Bornes, Laura and Hager, Carolina and Tang, Fengyuan and Santacroce, Natascha and Beisel, Christian and Ivanek, Robert and Bürglin, Thomas and Tiede, Stefanie and van Rheenen, Jacco and Christofori, Gerhard (2021) Distinct contributions of partial and full EMT to breast cancer malignancy. Developmental cell, 56 (23). 3203-3221.e11. ISSN 1878-1551

Lüönd, Fabiana and Tiede, Stefanie and Christofori, Gerhard (2021) Breast cancer as an example of tumour heterogeneity and tumour cell plasticity during malignant progression. British journal of cancer, 125 (2). pp. 164-175. ISSN 1532-1827


Machauer, Rainer and Lueoend, Rainer Martin and Hurth, Konstanze and Veenstra, Siem and Rueeger, Heinrich and Voegtle, Markus and Tintelnot-Blomley, Marina and Rondeau, Jean-Michel and Jacobson, Laura and Laue, Grit and Beltz, Karen and Neumann, Ulf (2021) Discovery of Umibecestat (CNP520): A Potent, Selective and Efficacious β-Secretase (BACE1) Inhibitor for the Prevention of Alzheimer’s Disease. Journal of Medicinal Chemistry, 64 (20). pp. 15262-15279. ISSN 0022-26231520-4804

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Manjunatha, Ujjini and Rao, Srinivasa and Smith, Paul and Westhuyzen, Renier van der and Chibale, Kelly (2021) Benzoheterocyclic Oxime Carbamates Active against Mycobacterium tuberculosis: Synthesis, Structure-Activity Relationship, Metabolism, and Biology Triaging. Journal of medicinal chemistry. ISSN 15204804

Marc, Philippe (2021) Data Science in R&D: it is about culture! Pharma Tech Outlook.

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Martin, Benjamin and Ladosz, Agnieszka and Battilocchio, Claudio (2021) Flow Chemistry Highlights column in Chimia (monthly contribution). Chimia : international journal for chemistry.

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Martin, Eric and Zhu, Xiangwei (2021) Collaborative Profile-QSAR: A Natural Platform for Building Collaborative Models among Competing Companies. Journal of chemical information and modeling, 61 (4). pp. 1603-1616. ISSN 1549960X

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Maziarz, Krzysztof and Jackson-Flux, Henry and Cameron, Pashmina and Sirockin, Finton and Schneider, Nadine and Stiefl, Nikolaus and Brockschmidt, Marc (2021) Learning to Extend Molecular Scaffolds with Structural Motifs. International Conference on Machine Learning.

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Meyer, Fabian and Frey, Raphael and Ligibel, Mathieu and Sager, Emine and Schroer, Kirsten and Snajdrova, Radka and Buller, Rebecca (2021) Modulating chemoselectivity in a Fe(II)/ alpha-ketoglutarate dependent oxygenase for the oxidative modification of a non-proteinogenic amino acid. ACS Catalysis , 11 (10). pp. 6261-6269.

Meyer, Robina M. and Berger, Lukas and Nerkamp, Joerg and Scheler, Stefan and Nehring, Sebastian and Friess, Wolfgang (2021) Identification of Monoclonal Antibody Variants Involved in Aggregate Formation - Part 1: Charge Variants. European journal of pharmaceutics and biopharmaceutics, 158. pp. 123-131. ISSN 1873-3441

Meyer., Robina M. and Berger, Lukas and Nerkamp, Joerg and Scheler, Stefan and Nehring, Sebastian and Friess, Wolfgang (2021) Identification of monoclonal antibody variants involved in aggregate formation – Part 2: Hydrophobicity variants. European Journal of Pharmaceutics and Biopharmaceutics, 160 (March ). pp. 134-142. ISSN 18733441

Miljković , Filip and Rodriguez Perez, Raquel and Bajorath, Jürgen (2021) Impact of Artificial Intelligence on Compound Discovery, Design, and Synthesis. ACS Omega.

Milton, Mark and Gorovits, Boris and Azedeh, Mitra and Buchlis, George and Harrisson, Travis and Havert, Mike and Jawa, Vibha and Long, Brian and McNally, Jim and Nelson, Robert and O'Dell, Mark and Richards, Karen and Vetterman, Christian and Wu, Bonnie (2021) Evaluation of the humoral response to viral-based Gene Therapy Modalities using Total Antibody assays. The AAPS journal, 23. p. 108. ISSN 1550-7416

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Muri, Lukas and Ispasanie, Emma and Schubart Wellensiek, Anna and Thorburn, Christine and Zamurovic Ribrioux, Natasa and Kammueller, Michael and Pluschke, Gerd (2021) Alternative Complement Pathway Inhibition Abrogates Pneumococcal Opsonophagocytosis in Vaccine-Naïve, but Not in Vaccinated Individuals. Frontiers in immunology, 12. ISSN 1664-3224


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Parmentier, Michael and Baudoin, Olivier and Antien, Kevin and Geraci, Andrea (2021) A New Dioxazolone for the Synthesis of 1,2-Aminoalcohols via Iridium(III)-Catalyzed C(sp3)–H Amidation. Angewandte Chemie International Edition. ISSN 1433-78511521-3773

Parmentier, Michael and Debrauwer, Vincent and Leito, Ivo and Lokov, Mart and Tshepelevitsh, Sofja and Blanchard , Nicolas and Bizet, Vincent (2021) Synthesis and Physico-Chemical Properties of 2-SF5-(Aza)Indoles, A New Family of SF5-Heterocycles. ACS Organic & Inorganic Au. ISSN 2694-247X2694-247X

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Unterreiner, Adeline and Rubert, Joelle and Kauffmann, Muriel and Fruhauf, Alice and Heiser, Diane and Erbel, Paulus and Schlapbach, Achim and Eder, Joerg and Bodendorf, Ursula and Boettcher, Andreas and Farady, Christopher and Bornancin, Frederic (2021) Pharmacological inhibition of IKKβ dampens NLRP3 inflammasome activation after priming in the human myeloid cell line THP-1. Biochemical and biophysical research communications : BBRC, 545. pp. 177-182. ISSN 0006291X


Valencia, Jessica and Megnin, Michelle and Collyar, Deborah and Guerreiro, Debra and Kashuba, Maureen and Klim, Lotte and Murray, Caragh and Patrick, Susan and Schindler, Thomas and Vashisht, Vidhi (2021) Presenting secondary endpoints in plain language clinical trial result summaries: Considerations for emerging practice. 'Medical Writing' - Quarterly publication produced by European Medical Writers Association , Volume (Issue ). pp. 58-67. ISSN 2047-4814

Velasco-Estevez, M and Koch, N and Klejbor, I and Laurent, Stephane and Dev, K and Szutowicz, A and Sailer, Andreas and Rutkowska, A (2021) Ebi2 is temporarily upregulated in mo3.13 oligodendrocytes during maturation and regulates remyelination in the organotypic cerebellar slice model. International Journal of Molecular Sciences, 22 (9). ISSN 14220067

Ventrella, Domenico and Ashkenazi, Nurit and Elmi, Alberto and Allegaert, Karel and Aniballi, Camilla and DeLise, Anthony and Devine, PJ and Smits, Anne and Steiner, Lilach and Forni, Monica and Bouisset-Leonard, Michele and Bacci, Maria Laura (2021) Animal models for in vivo lactation studies: anatomy, physiology and milk compositions in the most used non-clinical species, a contribution from the ConcePTION project. Animals, 11 (3). pp. 714-733. ISSN 2076-2615

Vermeulen, Koen and Cools, Romy and Briard, Emmanuelle and Auberson, Yves and Schoepfer, Joseph and Koole, Michel and Cawthorne, Christopher and Bormans, Guy (2021) Preclinical evaluation of [11C]YC-72-AB85 for in vivo visualisation of heat shock protein 90 in brain and cancer with positron emission tomography. Molecular Pharmaceutics, 18 (9). pp. 3352-3364. ISSN 1543-83841543-8392

Vidal, Justin and Colman, Karyn and Bhaskaran, Manoj and de Rijk, Eveline and Fegley, Darren and Haplern, Wendy and Jacob, Binod and Kandori, Hitoshi and Manickam, Balasubramanian and McKeag, Sean and Parker, George A. and Regan, Karen S. and Sefing, Benjamin and Thibodeau, Michael and Vemireddi, Vimala and Werner, Jonathan and Zalewska, Aleksandra (2021) Scientific and Regulatory Policy Committee Best Practices*: Documentation of Sexual Maturity by Microscopic Evaluation in Nonclinical Safety Studies. Toxicologic Pathology. ISSN 15331601

Vittal, Shivva and Fink, Martin and Lowe, Philip J (2021) Improving priors for human monoclonal antibody linear pharmacokinetic parameters by using half-lives from non-human primates. Journal of Pharmacokinetics and Pharmacodynamics. ISSN 15738744

Vorherr, Thomas (2021) Important considerations related to permeability of peptides. Chimia., 75 (6). pp. 522-524.

Vulpetti, Anna and Dalvit, Claudio (2021) Hydrogen Bond Acceptor Propensity of different Fluorine Atom Types: An Analysis of Experimentally- and Computationally-derived Parameters. Chemistry (Weinheim an der Bergstrasse, Germany), 27 (34). pp. 8764-8773. ISSN 15213765

van Hoogevest, Peter and Tiemessen, Harry and Metselaar, Josbert and Fahr, Alfred (2021) The Use of Phospholipids to make Pharmaceutical Form Line Extensions. European Journal of Lipid Science and Technology. ISSN 1438-76971438-9312


Waehle, Verena and Ungricht, Rosemarie and Hoppe, Philipp and Betschinger, Joerg (2021) The tumor suppressor WT1 drives progenitor cell progression and epithelialization to prevent Wilms tumorigenesis in human kidney organoids. Stem cell reports, 16. pp. 1-11. ISSN 2213-6711

Walker, Keenan A. and Chen, Jingsha and Zhang, Jingning and Fornage, Myriam and Tin, Adrienne and Daya, Natalie and Hoogeveen, Ron C and Wu, Aozhou and Sullivan, Kevin J and Ganz, Peter and Zeger, Scott L and Yang, Yunju and Gudmundsson, Elias F and Emilsson, Valur and Launer, Lenore J and Jennings, Lori and Gudnason, Vilmundur and Chatterjee, Nilanjan and Gottesman, Rebecca F and Mosley, Thomas H and Boerwinkle, Eric and Ballantyne, Christie M and Coresh, Josef and Zhou, Linda and Grams, Morgan E (2021) Large-scale plasma proteomic analysis identifies proteins and pathways associated with dementia risk. Nature Aging.

Walles, Markus (2021) Meeting report of the first European Biotransformation Workshop. Xenobiotica. pp. 1-6. ISSN 34284691

Walles, Markus and Hainzl, Dominik (2021) Risk-Based Pharmacokinetic and Drug-Drug Interaction Characterization of Antibody-Drug Conjugates in Clinical Development: An IQ Consortium Perspective. Clinical pharmacology and Therapeutics. ISSN 34657311

Wang, Hui-Qin and Mulford, Iain and Sharp, Fiona and Liang, Jinsheng and Kurtulus-Aksoylar, Sema and Trabucco, Gina and Quinn, David and Longmire, Tyler and Patel, Nidhi and Shirley, Matt and Chen, Yan and Wang, Hao and Ruddy, David and Fabre, Claire and Williams, Juliet and Hammerman, Peter and Mataraza, Jennifer and Platzer, Barbara and Halilovic, Ensar (2021) Inhibition of MDM2 promotes antitumor responses in p53 wild-type cancer cells through their interaction with the immune and stromal microenvironment. Cancer Research, 81 (11). pp. 3079-3091. ISSN 15387445

Wang, Xinting and Bartels, Christian and Kulkarni, Swarupa and Sangana, Ramachandra and Jain, Monish and Zack, Julia and Yu, Jing (2021) Population Pharmacokinetic Analysis of Fevipiprant in Healthy Subjects and Asthma Patients using a Tukey's g-and-h Distribution. Drug Research. ISSN 21949387

Wang, Zhongyi and Keogh, Adrian and Waldt, Annick and Cuttat-Theurillat, Rachel and Neri, Marilisa and Zhu, Shanshan and Schuierer, Sven and Ruchti, Alexandra and Crochemore, Christophe and Knehr, Judith and Jourdain, Marie and Weber, Delphine and Bastien, Julie and Roma, Guglielmo and Ksiazek, Iwona and Ge, Hui and Wu, Jing and Sánchez-Taltavull, Daniel and Helliwell , Stephen and Stroka , Deborah and Nigsch, Florian (2021) Single-cell and bulk transcriptomics of the liver reveals potential targets of NASH with fibrosis. Scientific reports, 11. ISSN 2045-2322

Wang-Lakshman, Lydia and Mendonza, Anisha and Huber, Roland and Walles, Markus and He, Yan-Ling and Jarugula, Venkateswar (2021) Pharmacokinetics, Metabolism, and Excretion of Licogliflozin, a Dual Inhibitor of SGLT1/2, in Rats, Dogs, and Humans. Xenobiotica.

Wang-Lakshman, Lydia and Zhuang, Miao and Wang, Lai and Gu, Helen and Gu, Jessie and McNamara, Elizabeth and Walles, Markus and Woessner, Ralph and Camenisch, Gian P. and Einolf, Heidi and Chen, Jin (2021) Evaluation of the Absorption, Metabolism, and Excretion of a Single Oral 1 mg Dose of Tropifexor in Healthy Male Subjects and the Concentration Dependency of Tropifexor Metabolism. Drug metabolism and disposition, 49 (7). pp. 548-562. ISSN 1521-009X

Wasserbacher, Helmut and Spindler, Martin (2021) Machine learning for financial forecasting, planning and analysis: recent developments and pitfalls. Digital Finance.

Weiss, Markus and Cain, Meredith and Langenickel, Thomas and Kulkarni, Swarupa and Shah, Bharti and Rahmanzadeh, Gholamreza and Poller, Birk and Vemula, Janardhana Rao (2021) Clinical investigation of metabolic and renal clearance pathways contributing to the elimination of fevipiprant using probenecid as perpetrator. Drug metabolism and disposition, 49 (5). pp. 389-394. ISSN 1521-009X

Widmer, Hans (2021) Open innovation: the many shades of a promising road to scientific discoveries. NCCR TransCure newsletter .

Willemsen, Joschka and Hoyler, Thomas and Noir, Emma and Tessier, Clemence and Sarret, Sophie and Thorsen, Tara Nicole and Littlewood-Evans, Amanda and Zhang, Juan and Rush, James and Guerini, Danilo and Siegel, Richard (2021) TNF leads to mtDNA release and cGAS/STING-dependent interferon responses that support inflammatory arthritis. Cell reports, 37 (6). p. 109977. ISSN 2211-1247

Woicke, Jochen and Al-Haddawi, Muthafar M and Bienvenu, Jean-Guy and Caverley Rae, Jessica M and Chanut, Franck J and Colman, Karyn and Cullen, John and Davis, Wendell and Fukuda, Ryo and Huisinga, Maike and Junker Walker, Ursula and Kai, Kiyonori and Kovi, Ramesh C and Macri, Nicholas P and Marxfeld, Heike-Antje and Nikula, Kristin J and Pardo, Ingrid D and Rosol, Thomas J and Sharma, Alok K and Singh, Bhanu P and Tamura, Kazutoshi and Thibodeau, Michael S and Vezzali, Enrico and Vidal, Justin D and Meseck, Emily (2021) International Harmonization of Nomenclature and Diagnostic Criteria (INHAND): Nonproliferative and Proliferative Lesions of the Dog. Toxicologic Pathology, 49 (1). pp. 5-109. ISSN 15331601

Wolf, Babette and Jeliazkova-Mecheva, Valentina and Del Rio Espinola, Alberto and Cochin de Billy, Benjamin and Boisclair, Julie and Walker, Dana and Flaherty, Meghan and Flandre, Thierry (2021) An afucosylated anti-CD32b monoclonal antibody induced platelet-mediated adverse events in human Fcg receptor transgenic mouse model and its potential human translatability. Toxicological sciences. ISSN 1096-0929; 1096-6080

Wolf, Thomas and Meishammer, Aldo and Patissier, Celine and Reck, Marcel and Valente, Claudio and Reilly, John (2021) Achiral SFC for Purification of Pharmaceuticals. Chromatography Today , Nov 20. pp. 12-14.

Wong, Nicole N. and Frias, Elizabeth and Sigoillot, Frederic and Letendre, Justin and Hild, Marc and Wong, Wilson W. (2021) Engineering digitizer circuits for chemical and genetic screens in human cells. Nature communications, 12 (1). p. 6150. ISSN 2041-1723

Wuensch, Isabell and Finke, Jan and John, Edgar and Juhnke, Michael and Kwade, Arno (2021) The influence of particle size on the application of compression and compaction models for tableting. International journal of pharmaceutics, 599 (n/a). 120424-n/a. ISSN 0378-5173

Wygant, Matthew and Kikuchi, Lena (2021) Reducing protein quantification bottlenecks by automating the Octet® HTX with a Hudson PlateCrane. Hudson Robotics Application Note.

Wünsch, Isabell and Michel, Stephanie and Finke, Jan Henrik and John, Edgar and Juhnke, Michael and Kwade, Arno (2021) How can single particle compression and nanoindentation contribute to the understanding of pharmaceutical powder compression? European Journal of Pharmaceutics and Biopharmaceutics, 165 (n/a). pp. 203-218. ISSN 0939-6411


Xu, Huilei and Hon, Claudia and Kaiser, Sergio and Serrano Fernandez, Pablo and Hartmann, Nicole and Yates, Denise and Healey, Margaret and Gusev, Arkady and Laramie, Jason and Kennedy, Scott and Marc, Philippe and Paul, Ridker and Obeidat, Maen and Beste, Michael and Svensson, Eric and Madar, Aviv (2021) Coronary artery disease polygenic risk score identifies patients at higher risk for recurrent cardiovascular events in the CANTOS Trial. Circulation: Genomics and Precision Medicine.


Zhang, Zhe (2021) Solving Complex Biologics Truncation Problems by Top-Down Mass Spectrometry. Journal of the American Society for Mass Spectrometry. ISSN 1879-1123; 1044-0305

Zhao, Kangming and Ge, Xiaobin and Zheng, Yu and Shen, Xiaodong and Shi, Lei and Gallou, Fabrice and Cortes-Clerget, Margery and Louis Regnier, Morgan and Parmentier, Michael and Ye, Ning and Wu, Bin (2021) Micelle enabled C(sp2)–C(sp3) cross-electrophile coupling in water via synergistic nickel and copper catalysis†. Chemical Communications, 57 (62). pp. 7629-7632. ISSN 1359-73451364-548X

Zhao, Yongmei and Tai Fang, Li and Shen, Tsai-wei and Houdhari, Sulbha and Talsania, Keyur and Chen, Jack and Shetty, Jyoti and Kriga, Yuliya and Tran, Bao and Zhu, Bin and Chen, Zhong and Chen, Wanqiu and Wang, Charles and Jaeger, Erich and Meerzaman, Daoud and Lu, Charles and Idler, Kenneth and Zheng, Yuanting and Shi, Leming and Petitjean, Virginie and Sultan, Marc and Hung, Tiffany and Eric, Peters and Drabek, Jiri and Vojta, Petr and Maestro, Roberta and Gasparotto, Daniela and Koks, Sulev and Reimann, Ene and Scherer, Andreas and Nordlund, Jessica and Liljedahl, Ulrika and Foox, Jonathan and Mason, Christopher and Xiao, Chunlin and Xiao, Wenming (2021) Whole genome and exome sequencing reference datasets from a multi-center and cross-platform benchmark study. Scientific data, 8 (1). p. 296. ISSN 2052-4463

Zhou, Lili and Miller, Caitlyn and Miraglia, Loren and Mendiola, Angelica and Mure, Ludovic S. and Panda, Satchidananda and Xiao, Changchun and Kay, Steve (2021) A genome-wide microRNA screen identifies the microRNA-183/96/182 cluster as a modulator of circadian rhythms. Proceedings of the National Academy of Sciences, 118 (1). ISSN 0027-84241091-6490

Zuo, Zhaorui and Wang, Penglei and Chen, Xiaowei and Tian, Li and Ge, Hui and Qian, Dahong (2021) SWnet: a deep learning model for drug response prediction from cancer genomic signatures and compound chemical structures. BMC bioinformatics, 22 (1). p. 434. ISSN 1471-2105

This list was generated on Thu Jun 30 03:22:30 2022 UTC.


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