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Meeting report of the first European Biotransformation Workshop

Walles, Markus (2021) Meeting report of the first European Biotransformation Workshop. Xenobiotica. pp. 1-6. ISSN 34284691


Challenges and opportunities in the field of biotransformation were presented and discussed at the 1st European Biotransformation workshop which was conducted virtually in collaboration with the DMDG January 27, 2021. Here we summarise the presentations and discussions from this workshop.
The following topics were covered:
• Needs for radiolabel for IND filing versus quantitation without standards
• Applications of cyclic ion mobility in the field of biotransformation
• Computational predictions of xenobiotic metabolism
• Future (outsourcing) needs in biotransformation
• Genotoxicity risk assessment of metabolites and qualification of impurities using metabolite data
• Regulatory aspects of MIST
Keywords: Biotransformation, metabolite qualification, cyclic ion mobility, MIST, genotoxicity risk assessment, qualification of impurities

Item Type: Article
Keywords: biotransformation
Date Deposited: 20 Aug 2021 00:45
Last Modified: 20 Aug 2021 00:45


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