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Auberson, Yves (2021) Reflections on 2018-2020. EFMC Yearbook, 2021. pp. 3-4.

Baczyk, Paulina and Wyss, Brigitte and Widmer, Jasmin and Hartmann, Steffen and Wassmann, Paul and Lobo, Susana and Jesus, Lídia and Gomes, Joana and Batista, Ana (2021) Stability liabilities of biotherapeutic proteins: early assessment as mitigation strategy. Journal of pharmaceutical and biomedical analysis, 192. pp. 1-15. ISSN 1873-264X; 0731-7085

Baran, Szczepan and Lim, Maria A. and Do, Johnny P. and Stolyar, Polina and Rabe, Mark D. and Schaevitz, Laura R. and Cadena, Samuel (2021) Digital biomarkers enable automated, longitudinal monitoring in a mouse model of aging. The journals of gerontology. Series A, Biological sciences and medical sciences. ISSN 1758535X

Boyle, Molly and Bennet, Bindu and Houle, Christopher D. and Sura, Radhakrishna and Colman, Karyn and Romeike, Annette and Frisk, Anna-Lena and Garcia, Begonya and Elmore, Susan A. (2021) Publication Categories in Toxicologic Pathology. Toxicologic Pathology. ISSN 15331601

Carbonneau, Seth and Sharma, Sujata and Peng, Liaomin and Rajan, Vaisakh and Hainzl, Dominik and Henault, Martin and Yang, Chian and Hale, Jacob and Shulok, Janine and Tallarico, John and Porter, Jeffrey and Brogdon, Jennifer and Dranoff, Glenn and Bradner, Jay and Hild, Marc and Guimaraes, Carla (2021) An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity. Cell Chemical Biology. ISSN 24519448

Cassaro, A and Grillo, G and Esposito, I and Reda, G and Cairoli, R and Beghini, A and Notaro, M and Gliozzo, J and Trojani, A and Valentini, G and Di Camillo, B (2021) FZD6 triggers Wnt–signalling driven by WNT10BIVS1 expression and highlights new targets in T cell acute lymphoblastic leukemia. Hematological oncology. ISSN 1099-1069

Dawson King, Janet and Vogelsanger, Melanie (2021) Cantharidin-induced skin blister as an in vivo model of inflammation. Current Protocols in Pharmacology , 1 (e49). pp. 1-14.

Diener, John and Mowbray, Sarah and Huang, WaanJeng and Yowe, David and Xu, Jian and Caplan, Shari and Misra, Abhay and Kapur, Ankur and Shapiro, Jeffrey and Ke, Xiaoling and Wu, Xiaoping and Bose, Avirup and Panza, Darrell and Chen, Min and Beaulieu, Valerie and Gao, Jiaping (2021) FGF21 Normalizes Plasma Glucose in Mouse Models of Type 1 Diabetes and Insulin Receptor Dysfunction. bioRxiv. pp. 1-19. ISSN

Dittrich, Birger (2021) On modelling disordered crystal structures through restraints from molecule-in-cluster computations,and distinguishing static and dynamic disorder. IUCrJ, International Union of Crystallography Journal , 8. pp. 305-318. ISSN 2052-2525

Dodd, Stephanie (2021) Use of PBPK Modeling for Predicting Drug-Food Interactions: Successful prediction using a middle-out approach. AAPS PharmSci, 23 (12). ISSN 1550-7416/21/0000-0001/0

Elo, Petri and Li, Xiang-Guo and Liljenbäck, Heidi and Gardberg, Maria and Moisio, Olli and Miner, Maxwell and Virta, Jenni and Saraste, Antti and Srinivasarao, Madduri and Pugh, Michael and Low, Philip and Knuuti, Juhani and Jalkanen, Sirpa and Airas, Laura and Lu, June and Roivainen, Anne (2021) Efficacy and tolerability of a folic acid derivative of aminopterin in a rat focal model of multiple sclerosis. J Neuroinflammation, 18 (30).

Fanous, Marina and Bitar, Malak and Gold, Sarah and Sobczuk, Adam and Hirsch, Stefan and Ogorka, Joerg and Imanidis, Georgios (2021) Immediate Release 3D-Printed Dosage Forms for Poorly Soluble Drugs: Development and Exploration of Morphology-Dissolution Relationship. International journal of pharmaceutics, 26. p. 120417. ISSN DOI: 10.1016/j.ijpharm.2021.120417

Gallou, Fabrice (2021) Late-stage cyanation of aryl/heteroaryl halides using ppm levels of a bidentate phosphine-derived palladacycle in water. ChemCatChem., 13 (1). pp. 212-216. ISSN 1867-3899; 1867-3880

Gallou, Fabrice (2021) Mild and robust Stille reactions in water using ppm levels of a new triphenylphosphine-based palladacycle. Angewandte Chemie. International edition, 60 (9). pp. 4158-4163.

Grass, Verena and Begue, Damien and Cordo, Valentina and Holzer, Laura and Martinuzzi-Duboc, Laetitia and Buhles, Alexandra and Kerr, Grainne and Barbosa, Ines and Naumann, Ulrike and Piquet, Michelle and Ruddy, David and Tordella, Luca and Weiss, Andreas and Ferretti, Stephane Raymond and Almeida, Reinaldo and Bonenfant, Debora and Galli, Giorgio (2021) Therapeutic Assessment of Targeting ASNS Combined with l-Asparaginase Treatment in Solid Tumors and Investigation of Resistance Mechanisms. ACS Pharmacology and Translational Sciences.

Hall, Peter and Flandre, Thierry and Piaia, Alessandro and Colman, Karyn and Tarnow, Inge and Price, Mark and Haworth, Richard and Vahle, John and Cary, Maurice and Jones, David and Cauvin, Annick (2021) BSTP Review of 12 Case Studies Discussing the Challenges, Pathology, Immunogenicity, and Mechanisms of Inhaled Biologics. Experimental and Toxicologic Pathology. ISSN 0192-62331533-1601

Hall, Peter and Vahle, John and Colman, Karyn (2021) Inspiration and Exasperation: The Challenges of Inhaled Biologics. Toxicologic Pathology. ISSN 15331601

Harlacher, Cornelius and Galli, Bruno and Meinel, Lorenz and Schlauersbach, Jonas and Hanio, Simon and Lenz, Bettina and Vemulapalli, Sahithya and Griesinger, Christian and Pöppler, Ann-Christin (2021) Leveraging bile solubilization of poorly water-soluble drugs by rational polymer selection. Journal of Controlled Release, 330. pp. 36-48. ISSN 18734995

Heusser, Carolyn and Garad, Sudhakar and Sanchez-Felix, Manuel and Ganish, Ahil (2021) Patient-centric design for systemic peptide delivery: Trends in routes of administration and advancement in drug delivery technologies. Medicine in Drug Discovery.

Heymsfield, Steven and Coleman, Laura and Miller, Ram and Rooks, Daniel and Laurent, Didier and Petricoul, Olivier and Praestgaard, Jens and Swan, Therese and Wade, Thomas and Perry, Robert and Goodpaster, Bret and Roubenoff, Ronenn (2021) Bimagrumab, an Activin Type II Receptor Antagonist, for the Treatment of Obesity and Type 2 Diabetes: A Randomized ClinicalTrial. Journal of the American Medical Association.

Jordaan, Pierre and Abi-Gerges, Najah and Dumotier, Berengere and Ghetti, Andrea and Urban, Laszlo and Miler, Paul (2021) Cardiotoxic Potential of Hydroxychloroquine, Chloroquine and Azithromycin in adult Human Primary Cardiomyocytes. Toxicological Sciences, e-pub (e-pub). pp. 1-13. ISSN 1096-60801096-0929

Keller, Steve and Quiroz, Jorge and Christopher, Dave and Wickremsinhe, Enaksha and Geng, Wanping and Hawthorne, Glen and James, Christopher and Katterle, Yvonne and Li, Wenkui and Liu, Guowen and Mayer, Andrew and Paton, Martin and Pav, Joseph and Potter, Julian and Vergis, James and Wang, Jonathan (2021) The effectiveness of quality control samples in pharmaceutical bioanalysis. Bioanalysis, 13 (3). pp. 135-145. ISSN 17576199

Kleinbeck-Riniker, Florian and Schlama, Thierry and Ruch, Thomas and Novick, Scott and Dellas, Nikki and Garcia, Ravi and Ching, Charlene and Bautista, Abby and Homan, David and Alvizo, Oscar and Entwistle, David (2021) Engineering an omega-Transaminase for the Efficient Production of a Chiral Sacubitril Precursor. ACS Catalysis, 11. pp. 3762-3770. ISSN 2155-54352155-5435

Kleinbeck-Riniker, Florian and Schlama, Thierry and Ruch, Thomas and Novick, Scott and Dellas, Nikki and Garcia, Ravi and Ching, Charlene and Bautista, Abby and Homan, David and Alvizo, Oscar and Entwistle, David (2021) Engineering an omega-Transaminase for the Efficient Production of a Chiral Sacubitril Precursor. ACS Catalysis, 11. pp. 3762-3770. ISSN 2155-54352155-5435

Krantz, Carsten (2021) Review of the Technical, Toxicological, and PKPD Considerations for Conducting Inhalation Toxicity Studies on Biologic Pharmaceuticals—The Outcome of a Cross-Industry Working Group Survey. Toxicologic Pathology. ISSN 15331601

Krell, Christoph and Gallou, Fabrice (2021) Water waste from surfactant chemistry: risk or opportunity? Organic process research & development, 25.

Lenz, Jan and Bunjes, Heike and Kwade, Arno and Juhnke, Michael (2021) An Improved Method for the Simultaneous Determination of Water Uptake and Swelling of Tablets. International journal of pharmaceutics, 595 (n/a). p. 120229. ISSN 1873-3476; 0378-5173

Lima, Fabio and Meisenbach, Mark and Schenkel, Berthold and Sedelmeier, Joerg Mathias (2021) Continuous Flow as an Enabling Technology: A Fast and Versatile Entry to Functionalized Glyoxal Derivatives. Organic & Biomolecular Chemistry. ISSN 1477-05201477-0539

Luo, Mai and Spradlin, Jessica and Boike, Lydia and Tong, Bingqi and Brittain, Scott and McKenna, Jeffrey and Tallarico, John and Schirle, Markus and Maimone, Thomas and Nomura, Dan (2021) Chemoproteomics-Enabled Ligand Screening Yields Covalent RNF114-Based Degraders that Mimics Natural Product Function. Cell chemical biology. ISSN 24519456

Markert, Christian and Thoma, Gebhard and Srinivas, Honnappa and Bollbuck, Birgit and Lueoend, Rainer Martin and Miltz, Wolfgang and Waelchli, Rudolf and Wolf, Romain and Hinrichs, Juergen and Bergsdorf, Christian and Azzaoui, Kamal and Penno, Carlos and Klein, Kai and Wack, Nathalie and Jaeger, Petra and Hasler, Franziska and Beerli, Christian and Loetscher, Pius and Dawson King, Janet and Wieczorek, Grazyna and Numao, Shin and Littlewood-Evans, Amanda and Roehn, Till (2021) Discovery of LYS006, a Potent and Highly Selective Inhibitor of Leukotriene A4 Hydrolase. Journal of medicinal chemistry.

Martin, Eric and Bosc, Nicolas and Felix, Eloy and Saunders, Martin R. and Green, Darren V. S. and Ochoada, Jason and Shelat, Anang A. and Iyer, Preeti and Engkvist, Ola and Verras, Andreas and Duffy, James and Gardner, J. Mark. F. and Leach, Andrew R. (2021) MAIP: A prediction platform for predicting blood-stage malaria inhibitors. Journal of Cheminformatics , 13 (1). p. 13. ISSN 1758-2946

Martus, Hans-Joerg and Erkman, Linda and Maremanda, Nihal and Elhajouji, Azeddine and Hartmann, Andreas (2021) Comprehensive review of genotoxicity data for diclofenac. Mutation research..

Maziarz, Krzysztof and Jackson-Flux, Henry and Cameron, Pashmina and Sirockin, Finton and Schneider, Nadine and Stiefl, Nikolaus and Brockschmidt, Marc (2021) Learning to Extend Molecular Scaffolds with Structural Motifs. International Conference on Machine Learning.

McIntosh, Avery and Sverdlov, Alex and Yu, Li and Kaufmann, Petra (2021) Clinical design and analysis strategies for development of cell and gene therapies: quantitative drug development in the age of genetic medicine. Clinical pharmacology and therapeutics. pp. 1-9.

Meyer, Robina M. and Berger, Lukas and Nerkamp, Joerg and Scheler, Stefan and Nehring, Sebastian and Friess, Wolfgang (2021) Identification of Monoclonal Antibody Variants Involved in Aggregate Formation - Part 1: Charge Variants. European journal of pharmaceutics and biopharmaceutics, 158. pp. 123-131. ISSN 1873-3441

Parmentier, Michael and Li, Wei and Dalton, Charlotte and Diorazio, Louis and Doerfler, Jaika and Engl, Olivier and Han, Zhengxu and Howell, Gareth and Hutchby, Marc and Latham, Jonathan and McLaws, Mark and Munday, Rachel and Navarro, Antonio and Pawlas, Jan and Roiban, Doru and Terrett, Jack and Treitler, Daniel and Zeng, Mingshuo and Steven, Alan (2021) Green Chemistry Articles of Interest to the Pharmaceutical Industry. Organic Process Research & Development. ISSN 1083-61601520-586X

Pikman, Yana and Tasian, Sarah K and Sulis, Maria Luisa and Stevenson, Kristen and Blonquist, Traci M and Apsel Winger, Beth and Cooper, Todd M and Pauly, Melinda and Maloney, Kelly W and Burke, Michael J and Brown, Patrick A and Gossai, Nathan and McNeer, Jennifer L and Shukla, Neerav N and Cole, Peter D and Kahn, Justine M and Chen, Jing and Barth, Matthew J and Magee, Jeffrey A and Gennarini, Lisa and Adhav, Asmani A and Clinton, Catherine M and Ocasio-Martinez, Nicole and Gotti, Giacomo and Li, Yuting and Lin, Shan and Imamovic, Alma and Tognon, Cristina E and Patel, Tasleema and Faust, Haley L and Contreras, Cristina F and Cremer, Anjali and Cortopassi, Wilian A and Garrido Ruiz, Diego and Jacobson, Matthew P and Dharia, Neekesh V and Su, Angela and Robichaud, Amanda L and Saur Conway, Amy and Tarlock, Katherine and Stieglitz, Elliot and Place, Andrew E and Puissant, Alexandre and Hunger, Stephen P and Kim, Annette S and Lindeman, Neal I and Gore, Lia and Janeway, Katherine A and Silverman, Lewis B and Tyner, Jeffrey W and Harris, Marian H and Loh, Mignon L and Stegmaier, Kimberly (2021) Matched Targeted Therapy for Pediatric Patients with Relapsed, Refractory or High-risk Leukemias: A Report from the LEAP Consortium. Cancer discovery. ISSN 2159-8290

SEBASTIANI, PAOLA and MONTI, STEFANO and FEDERICO, ANTHONY and Morris, Melody and GURINOVICH, ANASTASIA and TOSHIKO, TANAKA and BHUTKAR, APARNA and ANDERSON, STACY L and FERRUCCI, LUIGI and Glass, David and Jennings, Lori and PERLS, THOMAS T (2021) Protein signatures of centenarians and their offspring suggest centenarians age slower than other humans. Aging Cell. ISSN 14749726

Schmelzer, Bernhard and Mischo, André and Innerbichler, Franz (2021) Statistically significant versus practically relevant trend in stability data. PDA journal of pharmaceutical science and technology. ISSN 19482124

Schutzius, Gabi and Hauer, Christian and Bergling, Sebastian and Tortelli, Federico and Fuchs, Florian and Renner, Steffen and Guagnano, Vito and Cotesta, Simona and Rueeger, Heinrich and Faller, Michael and Bouchez, Laure and Salathe, Adrian and Nigsch, Florian and Richards, Shola and Louis, Malvina Caroline and Gruber, Viktoria and Aebi, Alexandra and Turner, Jonathan and Grandjean, Frederic and Li, Jun and Dimitri, Christopher and Thomas, Jason and Schirle, Markus and Blank, Jutta and Drueckes, Peter and Vaupel, Andrea and Tiedt, Ralph and Manley, Paul and Klopp, Julia and Hemmig, Rene and Zink, Florence and Leroy, Nelly and Carbone, Walter and Roma, Guglielmo and Gubser Keller, Caroline and Dales, Natalie and Beyerbach, Armin and Zimmerlin, Alfred Gilbert and Bonenfant, Debora and Terranova, Remi and Berwick, Amy and Sahambi, Sukhdeep and Reynolds, Aimee and Jennings, Lori and Ruffner, Heinz and Tarsa, Peter and Bouwmeester, Antonius and Driver, Vickie and Frederiksen, Mathias and Lohmann, Felix and Kirkland, Susan (2021) BET bromodomain inhibitors regulate keratinocyte plasticity. Nature Chemical Biology, 17 (3). pp. 280-290. ISSN 15524469

Singh, Ashish Kumar and Schauer, Tamas and Pfaller, Lena and Straub, Tobias and Mueller-Planitz, Felix (2021) The biogenesis and function of nucleosome arrays. bioRxiv.

Streubel-Gallasch, L and Giusti, V and Sandre, M and Tessari, I and Plotegher, N and Giusto, E and Masato, A and Iovino, L and Battisti, I and Arrigoni, G and Shimshek, Derya and Greggio, E and Tremblay, ME and Bubacco, L and Erlandsson, A and Civiero, L (2021) Parkinson’s Disease–Associated LRRK2 Interferes with Astrocyte-Mediated Alpha-Synuclein Clearance. Molecular Neurobiology. ISSN 15591182

To, Jeremy and Quackenbush, Doug and Rowell, Emily and Li, Lilin and Lo, Frederick and Horman, Shane (2021) A biomimetic assay platform for the interrogation of antigen-dependent anti-tumor T-cell function. Communications biology, 4. p. 56. ISSN 2399-3642

Tsai, Wan-Chen and Aleem, Ansari Mukhtar and Whittington, Chris and Cortopassi, Wilian A. and Kalyanaraman, Chakrapani and Baroz, Angel and Iavarone, Anthony T. and Skrzypczak-Jankun, Ewa and Jacobson, Matthew P. and Offenbacher, Adam R. and Holman, Theodore (2021) Mutagenesis, Hydrogen–Deuterium Exchange, and Molecular Docking Investigations Establish the Dimeric Interface of Human Platelet-Type 12-Lipoxygenase. Biochemistry, 60 (10). pp. 802-812. ISSN 0006-2960

Turner, Oliver and Rudmann, Daniel and Knight, Brian and Zuraw, Aleksandra and Litjens, Geert (2021) Mini Review: The Last Mile—Opportunities and Challenges for Machine Learning in Digital Toxicologic Pathology. Toxicologic pathology.

Vidal, Justin and Colman, Karyn and Bhaskaran, Manoj and de Rijk, Eveline and Fegley, Darren and Haplern, Wendy and Jacob, Binod and Kandori, Hitoshi and Manickam, Balasubramanian and McKeag, Sean and Parker, George A. and Regan, Karen S. and Sefing, Benjamin and Thibodeau, Michael and Vemireddi, Vimala and Werner, Jonathan and Zalewska, Aleksandra (2021) Scientific and Regulatory Policy Committee Best Practices*: Documentation of Sexual Maturity by Microscopic Evaluation in Nonclinical Safety Studies. Toxicologic Pathology. ISSN 15331601

Vittal, Shivva and Fink, Martin and Lowe, Philip J (2021) Improving priors for human monoclonal antibody linear pharmacokinetic parameters by using half-lives from non-human primates. Journal of Pharmacokinetics and Pharmacodynamics. ISSN 15738744

Wang, Xinting and Bartels, Christian and Kulkarni, Swarupa and Sangana, Ramachandra and Jain, Monish and Zack, Julia and Yu, Jing (2021) Population Pharmacokinetic Analysis of Fevipiprant in Healthy Subjects and Asthma Patients using a Tukey's g-and-h Distribution. Drug Research. ISSN 21949387

Wang-Lakshman, Lydia and Mendonza, Anisha and Huber, Roland and Walles, Markus and He, Yan-Ling and Jarugula, Venkateswar (2021) Pharmacokinetics, Metabolism, and Excretion of Licogliflozin, a Dual Inhibitor of SGLT1/2, in Rats, Dogs, and Humans. Xenobiotica.

Woicke, Jochen and Al-Haddawi, Muthafar M and Bienvenu, Jean-Guy and Caverley Rae, Jessica M and Chanut, Franck J and Colman, Karyn and Cullen, John and Davis, Wendell and Fukuda, Ryo and Huisinga, Maike and Junker Walker, Ursula and Kai, Kiyonori and Kovi, Ramesh C and Macri, Nicholas P and Marxfeld, Heike-Antje and Nikula, Kristin J and Pardo, Ingrid D and Rosol, Thomas J and Sharma, Alok K and Singh, Bhanu P and Tamura, Kazutoshi and Thibodeau, Michael S and Vezzali, Enrico and Vidal, Justin D and Meseck, Emily (2021) International Harmonization of Nomenclature and Diagnostic Criteria (INHAND): Nonproliferative and Proliferative Lesions of the Dog. Toxicologic Pathology, 49 (1). pp. 5-109. ISSN 15331601

Wuensch, Isabell and Finke, Jan and John, Edgar and Juhnke, Michael and Kwade, Arno (2021) The influence of particle size on the application of compression and compaction models for tableting. International journal of pharmaceutics, 599 (n/a). 120424-n/a. ISSN 0378-5173

Zhang, Zhe (2021) Solving Complex Biologics Truncation Problems by Top-Down Mass Spectrometry. Journal of the American Society for Mass Spectrometry. ISSN 1879-1123; 1044-0305

Zhou, Lili and Miller, Caitlyn and Miraglia, Loren and Mendiola, Angelica and Mure, Ludovic S. and Panda, Satchidananda and Xiao, Changchun and Kay, Steve (2021) A genome-wide microRNA screen identifies the microRNA-183/96/182 cluster as a modulator of circadian rhythms. Proceedings of the National Academy of Sciences, 118 (1). ISSN 0027-84241091-6490

van Hoogevest, Peter and Tiemessen, Harry and Metselaar, Josbert and Fahr, Alfred (2021) The Use of Phospholipids to make Pharmaceutical Form Line Extensions. European Journal of Lipid Science and Technology. ISSN 1438-76971438-9312

This list was generated on Sat Apr 17 06:50:26 2021 UTC.


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