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Items where Year is 2023

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Number of items: 167.


Aaron, Buaben and Pelis, Ryan (2023) Incubation Time Influences Organic Anion Transporter 1 Kinetics In Vitro and Renal Clearance Predictions for Para-Aminohippurate. Journal of xenobiotics., 13. pp. 205-217. ISSN 2039-4713

Amara, Kenza, Rodriguez Perez, Raquel and Jimenez-Luna, Jose (2023) Explaining compound activity predictions with a substructure-aware loss for graph neural networks. Journal of cheminformatics. ISSN 1758-2946

Amara, Kenza, Rodriguez Perez, Raquel and Jimenez-Luna, Jose (2023) Explaining compound activity predictions with a substructure-aware loss for graph neural networks. Journal of cheminformatics, 15 (1). p. 67. ISSN 1758-2946

Anders, Hans-Joachim, Roesti, David, Mohammadi, Mahsa and Bauer, Aline (2023) A rapid sterility method using solid phase cytometry for cell based preparations and culture media and buffers. PDA Journal of Pharmaceutical Science and Technology. ISSN 1079-74401948-2124

Auberson, Yves, Arimoondo, Paola, Duca, Maria, Essig, Sebastian, Grether, Uwe, Rufer, Arne, Sbardella, Gianluca, Schopfer, Ulrich, Torrens, Antoni, van der Stelt, Mario, Vauzeilles, Boris, Vazquez, Olalla and Zhang, Andrew (2023) EFMC: Trends in Medicinal Chemistry and Chemical Biology. Chembiochem : a European journal of chemical biology. e202200690. ISSN 1439-7633

Auberson, Yves, Benfatti, Fides, Gillingham, Dennis and Hartrampf, Nina (2023) An active member of EFMC: The Division of Medicinal Chemistry and Chemical Biology of the Swiss Chemical Society. ChemMedChem : chemistry enabling drug discovery. ISSN 1860-7187; 1860-7179

Auberson, Yves, Grether, Uwe, Vauzeilles, Boris and Vazquez, Olalla (2023) Mutually Rewarding Academia-Industry Collaborations in the Field of Chemical Biology. ChemBioChem.


Bagdanoff, Jeffrey, Smith, Thomas, Allan, Martin, O'Donnell, Peter, Nguyen, Zachary, Moore, Elizabeth, Baird, Jason, Wang, Shuangxi, Subramanian, Vanitha, Tigani, Bruno, Nettleton, David, Monovich, Lauren, Lewis, Ian, Flyer, Alec, Granda, Brian, Blankenship, John, Barnes-Seeman, David and Clairmont, Kevin (2023) Clearance of plasma PCSK9 via the asialoglycoprotein receptor mediated by heterobifunctional ligands. Cell chemical biology, 30 (1). 97-109.e9. ISSN 2451-9448

Bampali, Konstantina, Filip, Koniuszewski, Vogel, Florian, Fabian, Jure, Andronis, Christos, Lekka, Eftychia, Virvillis, Vassiis, Seidel, Thomas, Delaunois, Annie, Royer, Leandro, Rolf, Mike, Giuliano, Chiara, Traebert, Martin, Roussignol, Gautier, Fric-Bordat, Magali, Mazelin-Winum, Ludmilla, Bryant, Sharon, Langer, Thierry and Ernst, Margot (2023) GABAA receptor-mediated seizure liabilities: a mixed-methods screening approach. Cell biology and toxicology. ISSN 1573-6822

Barbosa, Ines, Gopalakrishnan, Rajaraman, Mercan, Samuele, Mourikis, Thanos, Martin, Typhaine, Wengert, Simon, Sheng, Caibin, Ji, Fei, Lopes, Rui, Knehr, Judith, Altorfer, Marc, Lindeman, Alicia, Russ, Carsten, Naumann, Ulrike, Golji, Javad, Sprouffske, Kathleen, Barys, Louise, Schmelzle, Tobias and Galli, Giorgio (2023) Cancer lineage-specific regulation of YAP responsive elements revealed through large-scale functional epigenomic screens. Nature communications, 14 (1). p. 3907. ISSN 2041-1723

Basu, Sumit, Ren, Xiaojun and Dodd, Stephanie (2023) Streamlining Food Effect Assessment — Are Repeated Food Effect Studies Needed? An IQ Analysis. Journal of Pharmaceutical Sciences, 25 (60).

Beckmann, Nicolau (2023) Editorial for "MRI Fat-Saturated T2-Weighted Radiomics Model for Predicting the Ki-67 Index of Soft Tissue Sarcomas”. Journal of magnetic resonance imaging, 58 (2). pp. 546-547. ISSN 10.1002/jmri.28563

Beckmann, Nicolau (2023) Editorial for "The effects of respiratory muscle training on resting state brain activity and thoracic mobility in healthy subjects: a randomized controlled trial”. Journal of magnetic resonance imaging, 57 (2). pp. 418-419. ISSN 1522-2586

Beckmann, Nicolau, Neuhaus, Anna, Zurbruegg, Stefan, Joller, Stefanie, Feuerbach, Dominik, Doelemeyer, Arno, Volkmer, Pia, Schweizer, Tatjana, Rudin, Stefan, Patino, Claudia, Neumann, Ulf, Berth, Ramon, Frieauff, Wilfried, Gasparini, Fabrizio and Shimshek, Derya (2023) Genetic models of cleavage-reduced and soluble TREM2 reveal distinct effects on myelination and microglia function in the cuprizone model. Journal of neuroinflammation, 20 (1). p. 29. ISSN 1742-2094

Bepperling, Alexander (2023) Comparison of three AUC techniques for the determination of the loading status and capsid titer of AAVs. European biophysics journal : EBJ. ISSN 1432-1017

Bepperling, Alexander and Richter, Gesa (2023) Determination of mRNA copy number in degradable lipid nanoparticles via density contrast analytical ultracentrifugation. European biophysics journal : EBJ. ISSN

Beri, Pranjali, Plunkett, Christopher, Barbara, Joshua, Shih, Chien-Cheng, Barnes, Whitney, Ross, Olivia, Choconta, Paula, Trinh, Ton, Gomez, Datzael, Litvin, Bella, Walker, John, Qiu, Minhua, Hammack, Scott and Toyama, Erin (2023) A high-throughput 3D cantilever array to model airway smooth muscle hypercontractility in asthma. APL bioengineering, 7 (2). 026104. ISSN 2473-2877

Beri, Pranjali, Plunkett, Christopher, Barbara, Joshua, Shih, Michael, Barnes, Whitney, Ross, Olivia, Choconta, Paula, Trinh, Ton, Litvin, Bella, Walker, John, Qiu, Minhua, Hammack, Scott and Toyama, Erin (2023) A high-throughput 3D cantilever array to model airway smooth muscle hypercontractility in asthma. APL bioengineering, 7 (2). 026104. ISSN 2473-2877

Bickel, Fabian, Griaud, Francois, Kern, Wolfram, Kroener, Frieder, Gritsch, Manuela, Dayer, Jerome, Barteau, Samuel, Denefeld, Blandine, Kao-Scharf, Chi-Ya, Lang, Manuel, Slupska-Muanza, Izabela, Schmidt, Carla, Berg, Matthias, Sigg, Juergen, Boado Chaves, Lina and Chelius, Dirk (2023) Restoring the biological activity of crizanlizumab at physiological conditions through a pH-dependent aspartic acid isomerization reaction. mAbs, 15 (1). 0-0. ISSN 1942-0862

Bigaud, Marc, Ramseier, Pamela, Tisserand, Sarah, Lang, Meike, Urban, Beatrice, Beerli, Christian and Karlsson, Goeril (2023) Central versus peripheral drug exposure ratio, a key differentiator for siponimod over fingolimod ? Neurology and Therapy. ISSN 2193-6536; 2193-8253

Blank, Jutta, Blechschmidt, Anke, Boettcher, Andreas, Bornancin, Frederic, Brady, Jacob, Eder, Joerg, Freuler, Felix, Haenni-Holzinger, Sandra, Hediger, Michael, Hommel, Ulrich, Hurth, Konstanze, Kaiser, Christian, Koch, Elke, Lehmann, Sylvie, Lehr, Philipp, Lingel, Andreas, Ostermeier, Daniela, Ramage, Paul, Rondeau, Jean-Michel, Tundo Dottorello, Valentina, Vulpetti, Anna, Yamamoto, Rina, Mureddu, Luca and Schleberger, Christian (2023) Discovery of a selective and biologically active low-molecular weight antagonist of human IL-1b. Nature communications, 14. pp. 5497-5509.

Blatter, Markus, Meylan, Charlotte, Cléry, Antoine, Giambruno, Roberto, Nikolaev, Yaroslav, Heidecker, Michel, Solanki, Jessica Arvindbhai, Diaz, Manuel, Gabellini, Davide and Allain, Frédéric H.-T. (2023) RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription. Science advances, 9 (16). eadf5330. ISSN 2375-2548

Bluemel, Markus and Gasser, Florian (2023) Current Industry Best Practice on In-Use Stability and Compatibility Studies of Biological Products. Journal of pharmaceutical sciences.

Bluemel, Markus and Gasser, Florian (2023) Current Industry Best Practice on in-use Stability and Compatibility Studies for Biological Products. Journal of pharmaceutical sciences. ISSN 1520-6017

Brenner, Anne, Brookbank, J.D. and Wang, Yingqi (2023) Faces of Mass Spectrometry/Karen Wang. Journal of the American Society for Mass Spectrometry, 34 (7). pp. 1207-1209. ISSN 1879-1123

Brosig, Sebastian, Cucuzza, Stefano, Serno, Tim, Bechtold-Peters, Karoline, Buecheler, Jakob, Zivec, Matej, Germershaus, Oliver and Gallou, Fabrice (2023) Not the Usual Suspects: Alternative Surfactants for Biopharmaceuticals. ACS applied materials & interfaces. ISSN 1944-8252


Carmen, Pessuti, Medley, Quintus, Li, Ning, Huang, Chia-Ling, Loureiro, Joe, Banks, Angela, Zhang, Qin, Costa, Deise, Ribeiro, Kleber, Nascimento, Heloisa, Muccioli, Cristina, Commodaro, Alessandra, Huang, Qian and Belfort, Rubens (2023) Differential proteins expression distinguished between patients with infectious and noninfectious uveitis. Ocular Immunology & Inflammation. ISSN 0927-3948 , 1744-5078

Chand, Deepa, Sun, Rui, Tukov, Francis, Damien, Kenny and Karim, Diab (2023) Review of cardiac safety in onasemnogene abeparvovec gene replacement therapy: translation from preclinical to clinical findings. Gene therapy. pp. 1-13. ISSN 1476-5462

Chapeau, Emilie and Schmelzle, Tobias (2023) IAG933, an oral selective YAP1-TAZ/pan-TEAD protein-protein interaction inhibitor (PPIi) with pre-clinical activity in monotherapy and combinations with MAPK inhibitors. Nature cancer.

Chen, Yue, Ge, Ying, Hao, Ling, Han, Xianlin, Huan, Tao, Li, Liang, Li, Lingjun, Li, Wenkui, Liang, Xiaorong, Lin, Yanping, Liu, Xiaowen, Liu, Yansheng, Ma, Shuguang, Peng, Junmin, Shou, Wilson, Sun, Liangliang, Tao, Andy W., Tian, Yu, Wang, Karen, Wang, Yinsheng, Wu, Ronghu, Wu, Si, Xia, Jianguo, Yang, Zhibo, Zhang, Hui, Zhang, Hui, Weng, Naidong and Huang, Lan (2023) Meeting Report on the 2nd Chinese American Society for Mass Spectrometry (CASMS) Conference. Molecular & cellular proteomics : MCP, 22 (6). pp. 1-13. ISSN 1535-9476

Concannon, John, Aspesi Jr, Peter, Cimini, Beth, Chandrasekaran, Srinivas, Kost-Alimova, Maria, Miller, Lisa, Goodale, Amy, Fritchman, Briana, Byrne, Patrick, Garg, Sakshi, Jamali, Nasim, Logan, David, Lardeau, Charles-Hugues, Mouchet, Elizabeth, Singh, Shantanu, Shafqat Abbasi, Hamdah, Boyd, Justin, Gilbert, Tamara, Gnutt, David, Hariharan, Santosh, Hernandez, Desiree, Hormel, Gisela, Juhani, Karolina, Melanson, Michelle, Mervin, Lewis, Monteverde, Tiziana, Pilling, James, Skepner, Adam, Swalley, Susanne, Vrcic, Anita, Weisbart, Erin, Williams, Guy, Yu, Shan, Zapiec, Bolek and Carpenter, Anne (2023) Optimizing the Cell Painting assay for image-based profiling. Nature methods, 18. pp. 1981-2013. ISSN 1750-2799

Cui, Elvis Han, Goldfine, Allison, Quinlan, Michelle, James, David and Sverdlov, Alex (2023) Investigating the value of glucodensity analysis of continuous glucose monitoring data in type 1 diabetes: An exploratory analysis. Frontiers in Clinical Diabetes and Healthcare.


Demir, Andac, Khalil, Iya and Kiziltan, Bulent (2023) EEG-NEXT: A MODERNIZED CONVNET FOR THE CLASSIFICATION OF COGNITIVE ACTIVITY FROM EEG. 2023 IEEE International Conference on Acoustics, Speech and Signal Processing.

Di Lascio, Elena, Gerebtzoff, Gregori and Rodriguez Perez, Raquel (2023) Systematic Evaluation of Local and Global Machine Learning Models for the Prediction of ADME Properties. Molecular pharmaceutics. ISSN 1543-8392

Di Lascio, Elena, Gerebtzoff, Gregori and Rodriguez Perez, Raquel (2023) Systematic Evaluation of Local and Global Machine Learning Models for the Prediction of ADME Properties. Molecular pharmaceutics. ISSN 1543-8392

Di Lascio, Elena, Yonchev, Dimitar and Hamzic, Seid (2023) People of TM: Video Data Science Academy Fellows. You Tube.

Dickinson, Michael, Barba, Pere, Jäger, Ulrich, Shah, Nirav N., Blaise, Didier, Briones, Javier, Shune, Leyla, Boissel, Nicolas, Bondanza, Attilio, Mariconti, Luisa, Marchal, Anne-Laure, Quinn, David, Yang, Jennifer, Price, Andrew, Sohoni, Akash Kamalakar, Treanor, Louise, Orlando, Elena, Mataraza, Jennifer, Davis, Jaclyn, Lu, Darlene, Xu, Zhu, Engels, Boris, Brogdon, Jennifer, de Parseval, Laure, Moschetta, Michele and Flinn, Ian (2023) A Novel Autologous CAR-T Therapy, YTB323, with Preserved T-Cell Stemness Shows Enhanced CAR T-Cell Efficacy in Preclinical and Early Clinical Development. Cancer discovery. ISSN 2159-8290

Dickinson, Michael, Barba, Pere, Jäger, Ulrich, Shah, Nirav N., Blaise, Didier, Briones, Javier, Shune, Leyla, Boissel, Nicolas, Bondanza, Attilio, Mariconti, Luisa, Marchal, Anne-Laure, Quinn, David, Yang, Jennifer, Price, Andrew, Sohoni, Akash Kamalakar, Treanor, Louise, Orlando, Elena, Mataraza, Jennifer, Davis, Jaclyn, Lu, Darlene, Zhu, Xu, Engels, Boris, Brogdon, Jennifer, de Parseval, Laure, Moschetta, Michele and Flinn, Ian (2023) A Novel Autologous CAR-T Therapy, YTB323, with Preserved T-Cell Stemness Shows Enhanced CAR T-Cell Efficacy in Preclinical and Early Clinical Development. Cancer discovery. ISSN 2159-8290

Diegel, Cassandra R., Kramer, Ina, Moes, Charles Gerard, Foxa, Gabrielle E., McDonald, Mitchell J., Madaj, Zachary B., Guth-Gundel, Sabine, Liu, Jun, Harris, Jennifer L., Kneissel, Michaela and Williams, Bart O. (2023) Inhibiting WNT secretion reduces high bone mass caused by Sost loss-of-function or gain-of-function mutations in Lrp5. Bone research, 11 (1). p. 47. ISSN 2095-6231

Ding, Jian, Li, Guo, Liu, Hejun, Liu, Lulu, Lin, Ying, Gao, Jingyan, Zhou, Guoqiang, Shen, Lingling, Zhao, Mengxi, Yu, Yanyan, Guo, Weihui, Hommel, Ulrich, Ottl, Johannes, Blank, Jutta, Aubin, Nicola, Wei, Yi, He, Hu, Sage, David, Atadja, Peter, Li, En, Jain, Rishi, Tallarico, John, Canham, Steve, Chiang, Yingling and Wang, He (2023) Discovery of Potent Small-Molecule Inhibitors of WDR5-MYC Interaction. ACS Chemical Biology. ISSN 1554-89291554-8937

Dittrich, Birger, Connor, Lauren, Werthmueller, Dominic, Sykes, Nicole and Udvarhelyi, Aniko (2023) Energy partitioning of pharmaceutical cocrystal structures. Cryst. Eng. Comm..

Dodge, Robert (2023) Neutralizing Antibody Validation Testing and Reporting Harmonization. The AAPS journal, 25 (4). p. 69. ISSN 1550-7416

Dunger-Baldauf, Cornelia, Hemmings, Rob, Bretz, Frank, Jones, Byron, Schiel, Anja and Holmes, Chris (2023) Generating the Right Evidence at the Right Time: Principles of a New Class of Flexible Augmented Clinical Trial Designs. Clinical pharmacology and therapeutics, 113 (5). pp. 1132-1138. ISSN 1532-6535


Erdemli, Gul, Curcic, Jelena, Brem, Anna-Katherine, Kuruppu, Sajini, de Boer, Casper, Muurling, Marijn, Diaz-Ponce, Ana, Gove, Dianne, Pilotto, Andrea, Ng, Wan-Fai, Cummins, Nicholas, Malzbender, Kristina, Nies, Vera J. M., Graeber, Johanna, Narayan, Vaibhav A., Maetzler, Walter, Rochester17,18, Lynn and Aarsland, Dag (2023) Digital endpoints in clinical trials of Alzheimer’s disease and other neurodegenerative diseases: challenges and opportunities. Frontiers in Neurology, 14. ISSN 1664-2295

Ertl, Peter, Altmann, Eva and Racine, Sophie (2023) The most common linkers in bioactive molecules and their bioisosteric replacement network. Bioorganic & medicinal chemistry, 81. p. 117194. ISSN 1464-3391


Fairchild, Lauren, Whalen, Jeanne, D'Aco, Katie, Wu, Jincheng, Gustafson, Ben, Su, Fei, Leary, Rebecca, Campbell, Katie and Balbin, Oscar (2023) Clonal hematopoiesis detection in patients with cancer using cell-free DNA sequencing. Science translational medicine, 15 (689). ISSN 1946-6242


Gallou, Fabrice (2023) Alternative synthesis of 5-(1H-Pyrazol-4-yl)-2-{6-[(2,2,6,6-tetramethylpiperidin-4-yl)oxy]pyridazin-3-yl}phenol. Helvetica Chimica Acta, 106 (3). e202200186.

Gallou, Fabrice (2023) Does the Red Shift in UV-Vis Spectra Really Provide a Sensing Option for Detection of N-nitrosamines Using Metalloporphyrins? ACS omega, 8 (1). pp. 1154-1167.

Gallou, Fabrice (2023) Ligand-Free Regioselective Aromatic Hydrogenation of Phosphine Oxide Scaffolds: An Easy Access to New Phosphine Ligands. Angewandte Chemie. International edition, 2023. ISSN 1521-3773; 0570-0833; 1433-7851

Gallou, Fabrice (2023) Palladium-catalyzed micellar cross-couplings : An Outlook. Coordination Chemistry Reviews, 488 (1). p. 215158.

Gallou, Fabrice (2023) Recent progress in Sonogashira-Hagihara cross-couplings in water. Chem Catalysis, 3 (1). p. 100485.

Gallou, Fabrice (2023) Recent progress in water-based Sonogashira cross-couplings in water. Chem Catalysis, 3 (1). 100485,. ISSN 2667-1093

Gallou, Fabrice (2023) Sustainable cascade water reaction combining transition metal-biocatalysis and hydrophobic substrates: The effect of solvent structuring. Chemical Journal of Engineering, 472. p. 144599.

Gallou, Fabrice (2023) "Where chemocatalysis meets biocatalysis ... in water. Nature–ally!". Chemical reviews.

Gimeno, Ramon, Ribas-Llaurado, Clara, Pesque, David, Andrades, Evelyn, Cenni, Bruno, Ambros, Barbara, Pujol, Ramon and Gimenez-Arnau, Ana Maria (2023) Remibrutinib inhibits hives effector cells stimulated by serum from chronic urticaria patients independently of FcεR1 expression level and omalizumab clinical response. Clinical and Translational Allergy, 13 (3). ISSN 2045-70222045-7022

Glowienke, Susanne (2023) Acceptable Intakes (AIs) for 11 Simple N-Nitrosamine (NA) Impurities. Regulatory toxicology and pharmacology.

Grandjean, Joanes, Doelemeyer, Arno, Zurbruegg, Stefan and Beckmann, Nicolau (2023) A consensus protocol for functional connectivity analysis in the rat brain. Nature neuroscience. ISSN 1546-1726; 1097-6256

Gray, Audrey, Bonazzi, Simone, Craig, Lucas, Capre, Ketthsy, Lubicka, Danuta, Curtis, Daniel, McTighe, Stephanie, Wilson, Christopher, Burdette, Doug, Dhamne, Sameer, Modi, Meera, Bainbridge, Elizabeth, Lalani, Lahin, Super, Chloe, Schaeffer, Samantha, Gurnani, Sarika, Vermudez, Sheryl Anne D, Hameed, Mustafa, D'Amore, Angelica, Rotenberg, Alexander and Sahin, Mustafa (2023) Seizure reduction in TSC2-mutant mouse model by an mTOR catalytic inhibitor. Annals of clinical and translational neurology. ISSN 2328-9503


Harwood, Matthew D, Zettl, Katharina, Weinheimer, Manuel, Pilla-Reddy, Venkatesh, Shen, Hong, Jacobs, Frank, Chu, Xiaoyan, Huth, Felix, Nakakariya, Masanori, Chothe, Paresh, Neuhoff, Sibylle and Wisniewski, Jacek R (2023) Interlaboratory Variability in the Madin-Darby Canine Kidney Cell Proteome. Molecular pharmaceutics. ISSN 1543-8392

Hassanein, Mohamed, Qiu, Iris, Zeng, Jianing and Hays, Amanda (2023) Drug Development Through the Prism of Biomarkers: Current State and Future Outlook. AAPS News Magazine.

Hawtin, Stuart, Andre, Cedric Bernard, Collignon Zipfel, Geraldine, Appenzeller, Simone, Bettina, Bannert, Baumgartner, Lea, Beck, Damian, Betschart, Claudia, Boulay, Thomas, Hermine, Brunner, Ceci, Melanie, Jonathan, Deane, Feifel, Roland, Ferrero, Enrico, Diego, Kyburz, Lafossas, Frederique, Loetscher, Pius, Merz-Stoeckle, Christina, Pierre, Michellys, Nuesslein-Hildesheim, Barbara, Raulf, Friedrich, James, Rush, Ruzzante, Giulia, Stein, Thomas, Zaharevitz, Samantha, Wieczorek, Grazyna, Siegel, Richard, Gergely, Peter, Shisha, Tamas and Junt, Tobias (2023) Preclinical characterization of the Toll-like receptor 7/8 antagonist MHV370 for lupus therapy. Cell reports. Medicine, 4 (5). p. 101036. ISSN 2666-3791

Heim, Sabina (2023) Zebrafish for drug discovery. Ascenion´s annual report 2021/22.

Heyndrickx, Wouter, Mervin, Lewis, Morawietz, Tobias, Sturm, Noe, Friedrich, Lukas, Zalewski, Adam, Pentina, Anastasia, Humbeck, Lina, Oldenhof, Martijn, Niwayama, Ritsuya, Schmidtke, Peter, Fechner, Nikolas, Simm, Jaak, Arany, Adam, Drizard, Nicolas, Jabal, Rama, Afanasyeva, Arina, Loeb, Regis, Verma, Shlok, Harnqvist, Simon, Holmes, Matthew, Pejo, Balazs, Telenczuk, Maria, Rieke, Nicola, Holway, Nicholas, Dieckmann, Arne, Zumsande, Friederike, Clevert, Djork-Arné, Krug, Michael, Luscombe, Christopher, Green, Darren, Ertl, Peter, Antal, Peter, Marcus, David, Do Huu, Nicolas, Fuji, Hideyoshi, Pickett, Stephen, Acs, Gergely, Boniface, Eric, Beck, Bernd, Sun, Yax, Gohier, Arnaud, Rippmann, Friedrich, Engkvist, Ola, Goeller, Andreas H., Moreau, Yves, Galtier, Mathieu, Schuffenhauer, Ansgar and Ceulemans, Hugo (2023) MELLODDY: Cross-pharma Federated Learning at Unprecedented Scale Unlocks Benefits in QSAR without Compromising Proprietary Information. Journal of chemical information and modeling. ISSN 1549-960X

Hien, Hsiaotzu, Prior, Helen, Andrews, Laura, Van Aerts, Leon, Cauvin, Annick, Clarke, David O., Datta, Kaushik, Dempster, Maggie, Dybdal, Noel, Freebern, Wendy, de Hann, Lolke, Herzyk, Danuta, Hey, Adam, Kissner, Thomas, Kronenberg, Sven, Leach, Michael W., Lee, Donna, Schutte, Karin, Sewell, Fiona, Trouba, Kevin, Ulrich, Peter, Weir, Lucinda and van Meer, Peter (2023) Re-evaluating the need for chronic toxicity studies with therapeutic monoclonal antibodies, using a weight of evidence approach. Regulatory Toxicology and Pharmacology, 138.

Hoch, Matthias, Bebrevska, Lidiya, Singh, Namrata and Hourcade-Potelleret, Florence (2023) Relative Bioavailability and Food Effect of Asciminib Pediatric Mini-tablet Formulation Compared to the Reference Tablet Formulation in Healthy Adult Participants. Clinical Pharmacology in Drug Development.


Isshiki, Takuma, Vierhout, Megan, Naiel, Safaa, Yazdanshenas, Parichehr, Kumaran, Vaishnavi, Ali, Pareesa, Yang, Zi, Dvorkin-Gheva, Anna, Rullo, Anthony F, Kolb, Martin and Ask, Kjetil (2023) Therapeutic strategies targeting pro-fibrotic macrophages in interstitial lung disease. Biochemical pharmacology. p. 115501. ISSN 1873-2968

Itskanov, Samuel, Wang, Laurie, Junne, Tina, Sheriff, Rumi, Blanchard, Nicolas, Shi, Wei, Forsyth, Craig, Hoepfner, Dominic, Spiess, Martin and Park, Eunyong (2023) A common mechanism of Sec61 translocon inhibition by small molecules. Nature chemical biology. ISSN 1552-4469


James, Alexander David, Kulmatycki, Ken, Poller, Birk, Romeo, Andrea, Van Lier, Jan Jaap, Klein, Kai and Pearson, David (2023) Absorption, Distribution, Metabolism, and Excretion of [14C]iptacopan in Healthy Male Volunteers and in In Vivo and In Vitro Studies. Drug metabolism and disposition: the biological fate of chemicals, 51 (7). pp. 873-883. ISSN 1521-009X

Ji, Yan, Madrasi, Kumpal, Knee, Deborah, Gruenbaum, Lore, Apgar, Joshua, Burke, John and Gomes, Bruce (2023) Quantitative systems pharmacology model of GITR-mediated T cell dynamics in tumor microenvironment. CPT: pharmacometrics & systems pharmacology, 12 (3). pp. 413-424. ISSN 2163-8306

Ji, Yan, Madrasi, Kumpal, Knee, Deborah, Gruenbaum, Lore, Apgar, Joshua, Burke, John and Gomes, Bruce (2023) Quantitative systems pharmacology model of GITR-mediated T cell dynamics in tumor microenvironment. CPT: pharmacometrics & systems pharmacology, 12 (3). pp. 413-424. ISSN 2163-8306

Ji, Yan, Yartsev, Vitaly, Quinlan, Michelle, Serra, Paolo, Wang, Yingbo, Chakraborty, Abhijit and Miller, Michelle (2023) Justifying Ribociclib Dose in Patients with Advanced Breast Cancer with Renal Impairment Based on PK, Safety, and Efficacy Data: An Innovative Approach Integrating Data from a Dedicated Renal Impairment Study and Oncology Clinical Trials. Clinical pharmacokinetics, 62 (3). pp. 493-504. ISSN 1179-1926

Ji, Yan, Yartsev, Vitaly, Quinlan, Michelle, Serra, Paolo, Wang, Yingbo, Chakraborty, Abhijit and Miller, Michelle (2023) Ribociclib Dose Justification in Advanced Breast Cancer Patients With Renal Impairment by Integrating PK, Safety and Efficacy Data. Clinical pharmacokinetics.

Johnson, Eric, Sutherland, Jeffrey, Meseck, Emily, McElroy, Cameron, Chand, Deepa, Tukov, Francis, Hudry, Eloise and Penraat, Kelley (2023) Neurofilament Light Chain and Dorsal Root Ganglia Injury After Adeno-Associated Virus 9 Gene Therapy in Nonhuman Primates. Molecular therapy: Methods and Clinical Development, 28. pp. 208-219. ISSN 2329-0501

Johnson, Eric, Sutherland, Jeffrey, Meseck, Emily, McElroy, Cameron, Chand, Deepa, Tukov, Francis, Hudry, Eloise and Penraat, Kelley (2023) Neurofilament light chain and dorsal root ganglia injury after adeno-associated virus 9 gene therapy in nonhuman primates. Molecular therapy. Methods & clinical development, 28. pp. 208-219. ISSN 2329-0501

Jonsdottir, Maria, K., Harrison, John and Hannesdottir, Kristin (2023) The ambivalence towards neuropsychology in dementia research, diagnosis, and drug development: Myths and misconceptions. Alzheimer's & dementia, 19 (5). pp. 2175-2181.


Kalamakis, Georgios and Platt, Randall J. (2023) CRISPR for neuroscientists. Neuron. ISSN 08966273

Kanji, Comfort Ropafadzo, Nyabadza, Georgina, Nhachi, Charles and Masimirembwa, Collen (2023) Pharmacokinetics of Tamoxifen and Its Major Metabolites and the Effect of the African Ancestry Specific CYP2D6*17 Variant on the Formation of the Active Metabolite, Endoxifen. Journal of personalized medicine, 13 (2). ISSN 2075-4426

Keuper-Navis, Marit, Walles, Markus, Poller, Birk, Myszczyszy, Adan, Van der Made, Thom, Donkers, Joanne, Eslami Amirabadi, Hossein, Wilmer, Martijn, Spee, Bart, Masereeuw, Rosalinde and Van de Steeg, Eviata (2023) The application of organ-on-chip models for the prediction of human pharmacokinetic profiles during drug development. Pharmacological research. p. 106853. ISSN 1096-1186

Konstantini, Christina, Spilioti, Evanthia, Bevernage, Jan, Ceulemans, Jens, Hansmann, Simone, Hellemans, Katleen, Jede, Christian, Kourentas, Alexandros, Reggane, Maude, Shah, Lipa, Wagner, Christian, Vertzoni, Maria and Reppas, Christos (2023) Screening for Differences in Early Exposure in the Fasted State with in Vitro Methodologies can be Challenging: Experience with the BioGIT System. Journal of pharmaceutical sciences. ISSN 1520-6017

Kostantini, Christina, Spilioti, Evanthia, Bevernage, Jan, Ceulemans, Jens, Hansmann, Simone, Hellemans, Katleen, Jede3, Christian, Kourentas, Alexandros, Reggane, Maude, Shah, Lipa, Wagner, Christian, Reppas, Christos and Vertzoni, Maria (2023) Usefulness of the BioGIT system in screening for differences in early exposure in the fasted state on an a priori basis. International journal of pharmaceutics. ISSN 03785173

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LaFollette, Megan R, Cloutier, Sylvie, Brady, Colleen M, O'Haire, Marguerite E and Gaskill, Brianna N (2023) Benchmarking Enrichment Efforts in the US & Canada Across Species and Enrichment Categories. Journal of the American Association for Laboratory Animal Science, 62 (4). pp. 1-14. ISSN 1559-6109

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Li, Wei and Steven, Alan (2023) Green Chemistry Articles of Interest to the Pharmaceutical Industry. Organic Process Research & Development, 27 (4). pp. 563-570. ISSN 1083-61601520-586X

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Liu, Lulu, Fang, Yanjia, Ding, Xiaodan, Zhou, Weihua, Terranova, Remi, Zhang, Yan and Wang, He (2023) Wdr5 is essential for fetal erythropoiesis and hematopoiesis. Experimental hematology & oncology, 12 (1). p. 39. ISSN 2162-3619

Liu, Lulu, Guo, Xin, Wang, Vickie, Li, Melody, Yu, Yanyan, Song, Yang, Zeng, Chenhui, Ding, Zhilou, Qiu, Yuanjun, Yan, Feifei, Zhang, Yixiang, Zhao, Caiqi, Zhang, Yan, Dou, Yali, Atadja, Peter, Li, En and Wang, He (2023) Loss of Wdr5 attenuates MLL-rearranged leukemogenesis by suppressing Myc targets. Biochimica et biophysica acta (BBA) - Molecular basis of disease, 1869 (2). p. 166600. ISSN 09254439

Liu, Lulu, Shen, Lingling, Ding, Zhilou, He, Miao, Li, En, Tallarico, John, Jain, Rishi and Wang, He (2023) Mechanism of Resistance to the WDR5 Inhibitor in MLL-Rearranged Leukemia. ACS chemical biology. ISSN 1554-8937

Liu, Samantha Y., Mulugeta, Naomi, Dougan, Stephanie K. and Qiang, Li (2023) In vitro flow cytometry assay to assess human and mouse macrophage phagocytosis of tumor cells. Cell. ISSN 1097-4172; 0092-8674


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Marulanda, Juliana, Tauer, Josephine, Boraschi-Diaz, Iris, Bardai, Ghalib and Rauch, Frank (2023) Effect of Sclerostin Inactivation in a Mouse Model of Severe Osteogenesis Imperfecta. Scientific reports.

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Monné Rodríguez, Josep M., Frisk, Anna-Lena, Kreutzer, Robert, Lemarchand, Thomas, Lezmi, Stephane, Saravanan, Chandrassegar, Stierstorfer, Birgit, Thuilliez, Céline, Vezzali, Enrico, Wieczorek, Grazyna, Yun, Seong-Wook and Schaudien, Dirk (2023) European Society of Toxicologic Pathology (Pathology 2.0 Molecular Pathology Special Interest Group): Review of In Situ Hybridization Techniques for Drug Research and Development. Toxicologic pathology. p. 1926233231178282. ISSN 1533-1601

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Nguyen, Tina, Lau, Anthony, Bier, Julia, Lenthall, Helen, Ruiz-Diaz, Stephanie, Brigden, Henry, Droney, Luke, Okada, Satoshi, Abolhassani, Hassan, Chavoshzadeh, Zarah, Abraham, Roshini, Rajapakse, Nipunie, Klee, Eric W, Church, Joseph A, Williams, Andrew, Wong, Melanie, Burkhart, Christoph, Uzel, Gulbu, Brink, Robert, Tangye, Stuart G and Deenick, Elissa K (2023) Human PIK3R1 mutations disrupt lymphocyte differentiation to cause activated PI3Kδ syndrome 2. The Journal of Experimental Medicine, 220 (6). ISSN 1540-9538


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Pistorius, Dominik, Buntin, Kathrin, Richard, Etienne, Rust, Michael, Bouquet, Caroline, Wollbrett, Severine, Weber, Eric, Dietschin, Daniele, Bruccoleri, Robert, Oakeley, Edward James and Petersen, Frank (2023) Valhidepsin Lipopeptides from Chromobacterium vaccinii: Structures, Biosynthesis, and Coregulation with FR900359 Production. Journal of natural products. ISSN 1520-6025

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Presenti, Sara (2023) Synthetic Oligonucleotides synthesis: current process and potential options for the future. Master thesis submitted at Università degli Studi di Perugia, 1 (1). p. 1. ISSN Master thesis submitted at Università degli Studi di Perugia

Prior, Helen, Andrews, Laura, Chien, Hsiaotzu, Clarke, David O, Kaushik, Datta, Dempster, Maggie, Ulrich, Peter, van Meer, Peter and Weir, Lucinda (2023) The use of recovery animals in nonclinical safety assessment studies with monoclonal antibodies: further 3Rs opportunities remain. Regulatory toxicology and pharmacology : RTP, 138. p. 105339. ISSN 1096-0295

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Reilly, Dorothy, Rocca-Serra, Philippe, Gu, Wei, Ioannidis, Vassilios, Abbassi Daloii, Tooba, Capella-Gutierrez, Salvador, Chandramouliswaran, Ishwar, Splendiani, Andrea, Burdett, Tony, GIessmann, Robert T., Henderson, David, Batista, Dominique, Lister, Allyson, Emam, Ibrahim, Gadiya, Yojana, Giovanni, Lucas, Gray, Alasdair J G, Gribbon, Philip, Juty, Nick, Welter, Danielle, Quast, Karsten, Peeters, Paul, Plasterer, Tom and Sansone, Susanna-Assunta (2023) The FAIR Cookbook - the essential resource for and by FAIR doers. Scientific data, 10 (1). p. 292. ISSN 2052-4463

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Reinhardt, Juergen, Link, Marion, Ibig-Rehm, Yvonne, Schmidt, Isabel, Galuba, Olaf, Schoenbett, Julian, Gasser-Didierlaurent, Christelle, Parker, Christian, Mao, Xiaohong, Bitsch, Francis, Couttet, Philippe, Sigoillot, Frederic, Schirle, Markus, Schmiedeberg, Niko, Muehlemann, Oliver, Gurzeler, Lukas-Adrian, Uldry, Anne-Christine, Ziegelmueller, Jana and Teodorowicz, Wojciech (2023) A novel molecule promotes readthrough at premature stop codons by inducing co-translational degradation of eRF1 involving GCN1, RNF14 and RNF25. Cell reports, 42 (Sep 26). pp. 1-30. ISSN 113056

Ren, Xiaojun, Dodd, Stephanie and Basu, Sumit (2023) STREAMLINING FOOD EFFECT ASSESSMENT – ARE REPEAT FOOD EFFECT STUDIES NEEDED? AN IQ ANALYSIS. The AAPS journal, 12248 (822). pp. 1-10. ISSN s12248-023-00822-5

Retson, Laura, Tiwari, Nishant, Vaughn, Jennifer, Bernes, Saunder, Adelson, David, Mansfield, Keith, Libertini, Silvana, Kuzmiski, Brent, Alecu, Iulian, Gabriel, Richard and Mangum, Ross (2023) Epithelioid neoplasm of the spinal cord in a child with spinal muscular atrophy treated with onasemnogene abeparvovec. Molecular therapy : the journal of the American Society of Gene Therapy. ISSN 1525-0024

Roth, Hans-Joerg, Stein, Richard and Fouche, Marianne (2023) Estimating intrinsic cooperativities and concentrations of ternary complexes in biochemical or cellular environments from binary dissociation constants, apparent cooperativities and total or free ligand concentrations. RSC Chemical Biology themed collection – Molecular Glues.

Roth, Hans-Joerg, Stein, Richard, Fouche, Marianne and Kearns, Jeff (2023) A model-informed method to retrieve intrinsic from apparent cooperativity and project cellular target occupancy for ternary complex-forming compounds. RSC chemical biology, 4 (7). pp. 512-523. ISSN 2633-0679

Roura Padrosa, David, Lehmann, Hansjoerg, Snajdrova, Radka and Paradisi, Francesca (2023) Sustainable synthesis of L-phenylalanine derivatives in continuous flow by immobilized phenyl ammonia lyase. Frontier Catalysis, 3.


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Schiller, Hilmar (2023) IQ Therapeutic Protein Drug-Drug Interaction White Paper. Clinical Pharmacology & Therapeutics. ISSN 0009-92361532-6535

Schiller, Hilmar (2023) Industry Perspective on Therapeutic Peptide Drug-Drug Interaction Assessments During Drug Development: A European Federation of Pharmaceutical Industries and Associations White Paper. Clinical pharmacology and therapeutics. ISSN 1532-6535

Schneider, Nadine, Lanini, Jessica, Rodriguez Perez, Raquel, Grisoni, Francesca, Nittinger, Eva, Riniker, Sereina, Andrea, Volkamer and Emma, Evertsson (2023) Machine Learning for Small Molecule Drug Discovery in Academia and Industry. Artificial Intelligence in the Life Sciences, 3. ISSN 26673185

Schroeder, Martin, Thoma, Claudio, Liang, Xiaoyou, Hofmann, Andreas, Meili, Fabian, Thomas, Jason, Sigoillot, Frederic, Gleim, Scott, Vulpetti, Anna, Zoller, Thomas, Ferrand, Sandrine, Chung, BoYee, Andraos-Rey, Rita and Niederst, Matt (2023) Reinstating targeted protein degradation with DCAF1 PROTACs in CRBN PROTAC resistant settings. BioRxiv.

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Seelinger, Felix (2023) Complex binding and elution behavior of therapeutic proteins under column overloading conditions. heiDOK – The Heidelberg Document Repository.

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Serrano Fernandez, Pablo, Kaiser, Sergio, Zhang, Luqing, Dovlatyan, Mary, Sanz, Vinicius, Li, Jingyao, Kostikova, Anna, Rotte, Michael and Messa, Mirko (2023) Parkinson’s disease causality and heterogeneity: a proteogenomic view. NPJ parkinson's disease, 9 (1). p. 24. ISSN 23738057

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Thoma, Gebhard, Vangrevelinghe, Eric, Luneau, Alexandre, Piechon, Philippe, Beerli, Christian and Zerwes, Hans Guenter (2023) Novel Concept for Super-Soft Topical Drugs: Deactivation by an Enzyme-Induced Switch into an Inactive Conformation. ACS medicinal chemistry letters, 14. ISSN 1948-5875

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Wallimann, Rahel, Schindler, Patrick, Hensinger, Heloise, Kneuer, Rainer, Tschan, Viviane, Busslinger, Sarah, Müller, Cristina and Schibli, Roger (2023) High-sensitivity ICP-MS is a valid method for the preclinical characterization of metal-conjugates to be developed as future radiopharmaceuticals. Molecular pharmaceutics, 20 (4). pp. 2150-2158. ISSN 1543-8384

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Werthmueller, Dominic, Schlauersbach, Jonas, Harlacher, Cornelius, Galli, Bruno, Hanio, Simon, Lenz, Bettina, Endres, Sebastian, Pöppler, Ann-Christin, Scherf-Clavel, Oliver and Meinel, Lorenz (2023) Harnessing Bile for Drug Absorption through Rational Excipient Selection. Molecular pharmaceutics. ISSN 1543-8392

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This list was generated on Tue Oct 3 22:53:21 2023 UTC.


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