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Auld, Douglas and Nettleton, David (2024) Tight-binding small molecule carboxylesterase 2 inhibitors reduce intracellular Irinotecan activation. Journal of medicinal chemistry. ISSN 1520-4804; 0022-2623

Axelsson, GT, Loureiro, Joe, Orth, Anthony, Jennings, Lori and Gudnason, Vilmundur (2024) Proteomic associations with forced expiratory volume – a Mendelian randomisation study. Respiratory Research.

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Baert, Lore Sarah, Mueller, Matthias, Doll, Thierry and Pellisson, Melanie (2024) iPS-derived human macrophages as an infection model for Leishmania donovani. PLoS neglected tropical diseases, 18. ISSN 1935-2735

Barbier, Nathalie, Dunger-Baldauf, Cornelia, Devenport, Jenny and Dyachkova, Yulia (2024) Do you want to stay single? Considerations on single arm trials in the post-regulatory space. Pharmaceutical Statistics. pp. 1-12.

Bartko, Theresa, Lutgen, Stephen, Ross, Rebecca, Walisser, Jacqueline, Garske, Eric, Kopelke, Kerry, Ashcroft-Hawley, Kelly, Tang, Hai-Ming, Kremer, John, Friedrichs, Gregory and Nichols, Jill (2024) Optimized J to T peak and T peak to T end measurements in nonclinical species administered moxifloxacin and amiodarone. Journal of pharmacological and toxicological methods. p. 107527. ISSN 1873-488X

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Bernier, Jacques, Magnin, Isabelle, le Gallic de Kerizouët, Esthelle, Kenfak, Alain, Boschung, Jacques and Rebhan, Michael (2024) Revolutionizing Health Care Management: The 8Ps Value Proposition. Harvard business review : HBR.

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Borges, Beltran, Varthaliti, Antonia, Schwab, Marisa, Clarke, Maria/T, Pivetti, Christopher, Gupta, Nalin, Guibinga, Ghiabe, Phillips, Shirley, Del Rio, Tony, Ozsolak, Fatih, Imai-Leonard, Denise, Kong, Lingling, Laird, Diana/J, Herzeg, Akos, Sumner, Charlotte/J and Mackenzie, Tippi/C (2024) Prenatal administration of AAV9-GFP in fetal lambs results in widespread distribution into brain and spinal cord and transduction of female germ cells. Molecular therapy - methods and clinical development. ISSN 2329-0501

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Brennan, Richard, Jenkinson, Stephen, Brown, Andrew, Delaunois, Annie, Dumotier, Berengere, Pannirselvam, Malar, Rao, Mohan, Ribeiro, Lyn, Schmidt, Friedemann, Sibony, Alicia, Timsit, Yoav, Sales, Vicencia, Armstrong, Duncan, Lagrutta, Armando, Mittelstadt, Scott, Naven, Russ, Peri, Ravikumar, Roberts, Sonia, Vergis, James and Valentin, Jean-Pierre (2024) Author Correction: The state of the art in secondary pharmacology and its impact on the safety of new medicines. Nature reviews. Drug discovery. ISSN 1474-1784

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Brown, Alan, Friedrichs, Gregory, Traebert, Martin, Weber, Valerie, Yao, Nancy, Tang, Hai-Ming and Yan, Gan-Xin (2024) Electrophysiological changes in the rabbit ventricular wedge assay and in human-induced pluripotent stem-cell derived (IPSC) cardiomyocytes provided correlates to severe arrhythmia observed in a dog toxicology study, whereas standard in vitro ion channel assays were not predictive of adverse cardiovascular change. International Journal of Toxicology. pp. 1-12. ISSN DOI: 10.1177/10915818241230900

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Chapeau, Emilie, Schmelzle, Tobias and Soldermann, Nicolas (2024) Direct and selective pharmacological disruption of the YAP-TEAD interface inhibits cancers with genetic alterations in the Hippo and RAS-MAPK pathways. Nature Cancer.

Chen, Hao, King, Frederick, Zhou, Bin, Wang, Yu, Canedy, Carter, Hayashi, Joel, Zhong, Yang, Chang, Max, Pache, Lars, Wong, Julian, Jia, Yong, Joslin, John, Jiang, Tao, Benner, Christopher, Chanda, Sumit and Zhou, Yingyao (2024) Drug target prediction through deep learning functional representation of gene signatures. Nature communications, 15 (1). p. 1853. ISSN 2041-1723

Claas, Allison, Lee, Meelim, Huang, Pai-Hsi, Knutson, CHARLIE, Bullara, Dom, Schoeberl, Birgit and Gaudet, Suzanne (2024) Viral Kinetics Model of SARS-CoV-2 Infection Informs Drug Discovery, Clinical Dose, and Regimen Selection. Clinical pharmacology and therapeutics. ISSN 1532-6535

Constantine, LA, Davidson, T, Häner, A, Janer Gual, Gemma, Maynard, SK, Lee, M, Perkins, AN, Ryan, JJ, Tell, J, Van Ginneken, I, Burden, N and Dolan, D (2024) EVALUATION OF THE EMA TRIGGER FOR FISH BCF TESTING AND SECONDARY POISONING ASSESSMENT: EVALUATION OF LOG D AND FISH BCF DATA FOR SEVERAL PHARMACEUTICALS. Regulatory toxicology and pharmacology, 151 (105651). pp. 1-11. ISSN 1096-0295; 0273-2300

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Cremosnik, Gregor, Mesrouze, Yannick, Zueger, Patrik, Furkert, David, Grandjean, Frederic, Argoti, Dayana, Mermet-Meillon, Fanny, Bauer, Matthias, Brittain, Scott, Tang, Jenny, Knapp, Mark, Holzinger, Sandra, Buhr, Sylvia, Muller, Lionel, Leder, Lukas, Xie, Lili, Fernandez, Cesar, Nieto-Oberhuber, Cristina, Chene, Patrick, Galli, Giorgio and Sesterhenn, Fabian (2024) mRNA Display Identifies Potent, Paralog-Selective Peptidic Ligands for ARID1B. ACS Chemical Biology. ISSN 1554-89291554-8937

Cuyckens, Filip, Hvenegaard, Mette G, Cassidy, Kenneth C, Spracklin, Douglas K, James, Alexander David, Pederson, Mette L, Scarfe, Graeme, Wagner, David S, Georgi, Katrin, Schieferstein, Hanno, Bjornsdottir, Inga, Romeo, Andrea A, Da-violante, Georges, Blech, Stefan, Hoffman, Matthew, Schulz, Simone, Moliner, Patricia and Young, Graeme C (2024) Recommendations on the Use of Multiple Labels in Human Mass Balance Studies. Drug metabolism and disposition: the biological fate of chemicals, 52 (3). pp. 153-158. ISSN 1521-009X

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Daniel, Puckhaber, Jan Henrik, Finke, David, Sarah, Gururajan, Bindhu, Rane, Supriya and Arno, Kwade (2024) Effect of particle size on the dispersion behavior of magnesium stearate blended with microcrystalline cellulose. International journal of pharmaceutics. p. 123792. ISSN 1873-3476

Danilack, Aaron, Dickson, Callum, Soylu, Cihan, Fortunato, Mike, Rodde, Stephane, Hornak, Viktor and Duca, Jose (2024) Reactivities of acrylamide warheads toward cysteine targets: a QM/ML approach to covalent inhibitor design. Journal of chemical information and modeling, 38 (21).

De Caro, Liberato, Stoll, Thibaud, gozzo, fabia and Giannini, Cinzia (2024) Characterization of Surfactant Spheroidal Micelle Structure for Pharmaceutical Applications: A Novel Analytical Framework. Pharmaceutics, 16 (5). ISSN 1999-4923

Devarakonda, Murthy, Mohanty, Smita, Sunkisala, Raja Rao, Mallampalli, Nag and Liu, Xiong (2024) Clinical trial recommendations using Semantics-Based inductive inference and knowledge graph embeddings. Journal of biomedical informatics, 154. p. 104627. ISSN 1532-0480

Dhareshwar, Sundeep, Matharu, Amol and Cao, Yu(Jade) (2024) Identifying chemical stabilizers - presenting a case study using a rapid 3-day accelerated excipient screening methodology. AAPS PharmSciTech, 12 (25). ISSN 1530-9932

Digles, Daniela, Ingles-Prieto, Alvaro, Dvorak, Vojtech, Mocking, Tamara, Goldmann, Ulrich, Garofoli, Andrea, homan, Evert, Leippe, Philipp, Di Silvio, Alberto, Azzollini, Lucia, Sassone, Francesca, Forgazza, Mario, Bearenz, Felix, Pommereau, Antje, Zuschlag, Yasmin, Ooms, Jasper, Transberg-jensen, Jeppe, Hansen, Jesper, Stanka, Josefina, Jijben, Hubert, Batoulis, Helena, Bender, Eckert, Martini, Riccardo, Sosnin, Sergey, Ilzerman, Adriaan, Sauer, David, Heitman, Laura, Manolova, Vania, Reinhardt, Juergen, Ehrmann, Alexander, Ecker, Gerhard, Widmer, Tabea, Huber, Kilian, Licher, Thomas, Scarabottolo, lia and Superti-Furga, Giulio (2024) Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily. Frontiers in pharmacology, 15 (15). pp. 1-16. ISSN 1663-9812

Dittrich, Birger, Connor, Lauren, Fabbiani, Francesca and Piechon, Philippe (2024) Linking solid-state phenomena via energy differences in `archetype crystal structures'. IUCrJ. ISSN 2052-2525

Dominy, John, Koch, Christopher-1, Lamarche, Lindsey, Denning, Daniel, Gurtan, Allan, Khan, Maleeha, Rasheed, Asif, Mian, Muhammad, Jahanzaib, Muhammad, Khalid, Shareef and Saleheen, Danish (2024) Corin and Left Atrial Cardiomyopathy, Hypertension, Arrhythmia, and Fibrosis. The New England journal of medicine, 390 (16). pp. 1537-1538. ISSN 1533-4406

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Elbatsh, Ahmed, Maira, Michel and Manchado Robles, Eusebio (2024) INPP5A phosphatase is a synthetic lethal target in GNAQ and GNA11-mutant melanomas. Nature cancer. ISSN 2662-1347

Ertl, Peter (2024) Database of 4 Million Medicinal Chemistry-Relevant Ring Systems. Journal of chemical information and modeling, 64 (4). pp. 1245-1250. ISSN 1549-960X

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Felip, Enriqueta, Metro, Giulio, Tan, Daniel, Wolf, Juergen, Mark, Michael, Boyer, Michael, Hughes, Brett, Bearz, Alessandra, Moro-Sibilot, Denis, Le, Xiuning, Puente, Javier, Massuti, Bartomeu, Tiedt, Ralph, Wang, Yingying, Xu, Chao, Mardjuadi, Feby Ingriani and Cobo, Manuel (2024) Capmatinib plus nivolumab in pretreated patients with EGFR wild-type advanced non-small cell lung cancer. Lung cancer (Amsterdam, Netherlands), 192. p. 107820. ISSN 1872-8332

Flandre, Thierry, Salian-Mehta, Smita, Smith, James, Lambert, Amy, Lane, Joan, Stokes, Alan, Orsted, Kathy, Bratcher-Petersen, Natalie, Janardhan, Kyathanahalli and Tonkin, Elizabeth (2024) Recovery Animals in Toxicology Studies: An Innovation and Quality Consortium Perspective on Best Practices With Case Study Examples. International journal of toxicology. p. 10915818241243350. ISSN 1092-874X

Fluetsch, Andrin, Di Lascio, Elena, Gerebtzoff, Gregori and Rodriguez Perez, Raquel (2024) Adapting Deep Learning QSPR Models to Specific Drug Discovery Projects. Molecular Pharmaceutics. ISSN 1543-83841543-8392

Fluetsch, Andrin, Trunzer, Markus, Gerebtzoff, Gregori and Rodriguez Perez, Raquel (2024) Deep Learning Models Compared to Experimental Variability for the Prediction of CYP3A4 Time-Dependent Inhibition. Chemical research in toxicology, 37 (4). pp. 549-560. ISSN 1520-5010

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Gallou, Fabrice (2024) Greener Methodologies in Organic Chemistry: A Pathway Towards Sustainable Future. Green Chemistry, 26. pp. 6289-6317.

Gallou, Fabrice (2024) Manganese(I)-Catalyzed Functionalization of Tryptophan on Water. Synlett, 35 (8). pp. 903-907.

Gallou, Fabrice (2024) Protecting-Group-Free Mechanosynthesis of Amides from Hydroxycarboxylic Acids. RSC Mechanochemistry, 1. pp. 189-195.

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Gallou, Fabrice and Plummer, Scott (2024) Buchwald-Hartwig Aminations of Aryl Halides Using Nitroaromatics as Coupling Partners: Overcoming Hydrodehalogenation Pathway in Water. ACS Catalysis, 14 (6). pp. 4099-4107.

Gao, Feng and Gallou, Fabrice (2024) Chemoenzymatic Synthesis of 2-Aryl-thiazolines fr. Angewandte Chemie. International edition. e202405833.

Gao, Yan, Bray, Mark, Twarog, Michael, Xu, YongYao, Buchanan, Natasha, Zhang, Yiyun-1, Medley, Quintus, Saint-Geniez, Magali, Prasanna, Ganesh and Zhang, Qin (2024) Use of machine learning for quantification of retinal pigment epithelium tight junctions improves assay sensitivity. Experimental eye research.

Gatlik, Ewa, Mehes, Beata, Voltz, Emilie Francoise, Sommer, Ulrike, Tritto, Elaine, Lestini, Giulia, Pal, Parasar, Fu, Yunlin, Opipari, Anthony, Dennis, Dean and Junge, Guido (2024) First-in-human safety, tolerability, and pharmacokinetic results of DFV890, an oral low-molecular-weight NLRP3 inhibitor. Clinical and translational science, 17 (5). e13789. ISSN 1752-8062

Gellermann, Gerald, Kirsch, Stephan and den Engelsman, John (2024) Fine-tuning Analytical Development Strategies For Every Phase. Bioprocess Online.

Godinez Navarro, William, Trifonov, Vladimir, Fang, Bin, Kuzu, Guray, Pei, Amy, Guiguemde, Armand, Martin, Eric, King, Frederick, Jenkins, Jeremy and Skewes-Cox, Peter (2024) Compound activity prediction with dose-dependent transcriptomic profiles and deep learning. Journal of Chemical Information and Modeling. ISSN 1549-95961549-960X

Grevot, Armelle, Boisclair, Julie, Irizarry, Armando, Guffroy, Magali, Hall, Peter, Pohlmeyer-Esch, Gabriele, Jacobsen, Matt, Bach, Ute, Frisk, Ana Lena, Dybdal, Noel and Palazzi, Xavier (2024) Use of virtual control groups in nonclinical toxicity studies: the anatomic pathology perspective. Experimental and Toxicologic Pathology. ISSN 0192-62331533-1601

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Hendrickx, Gretl, Boudin, Eveline, Mateiu, Ligia, Yorgan, Timur A., Steenackers, Ellen, Kneissel, Michaela, Kramer, Ina, Mortier, Geert, Schinke, Thorsten and Van Hul, Wim (2024) An Additional Lrp4 High Bone Mass Mutation Mitigates the Sost-Knockout Phenotype in Mice by Increasing Bone Remodeling. Calcified tissue international, 114 (2). pp. 171-181. ISSN 1432-0827

Heuser, Alisa, Abdul Rahman, Wassim, Bechter, Elisabeth, Blank, Jutta, Buhr, Sylvia, Fontana, Patrizia, Meyerhofer, Marco, Strang, Ross, Schrapp, Maxime, Zimmermann, Catherine, Cortes-Cros, Marta, Moebitz, Henrik, Hamon, Jacques, Mermet-Meillon, Fanny and Erdmann, Dirk (2024) Challenges for the Discovery of Non-Covalent WRN Helicase Inhibitors. ChemMedChem.

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Iyer, Ganesh, Darpo, Borje, Xue, Hongqi, Lecot, Jean, Zack, Julia, Bebrevska, Lidiya, Weis, Wendy and Drollmann, Anton Franz (2024) Concentration-QTcF modeling of Icenticaftor from a randomized, placebo- and positive-controlled thorough QT (TQT) study in healthy participants. Journal of cystic fibrosis :. pp. 1-13. ISSN 2160-763X

Izem, Rima, Zuber, Emmanuel, Daizadeh, Nadia, Bretz, Frank, Sverdlov, Alex, Edrich, Pascal, Branson, Janice, Degtyarev, Evgeny, Sfikas, Nikolaos and Hemmings, Robert (2024) Decentralized clinical trials: scientific considerations through the lens of the estimand framework. Therapeutic Innovation and Regulatory Science.

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Ji, Yan and Sy, Sherwin (2024) Utility and impact of quantitative pharmacology on dose selection and clinical development of immuno-oncology therapy. Acta Pharmaceutica Sinica B.

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Khera, Eshita (2024) People of TM: Videos of Eshita Khera. LinkedIn.

Klokman, Garrett, Xu, YongYao, Bond, Kyle, Wu, Xiaoqiu, Schustak, Joshua, Mandelbaum, Jorgi, Twarog, Michael, Han, Hongwei, Paulina, Mary-Kate, Coble, Matthew, Hayden, Chris, Galarneau, Jean-Rene, Demirs, John, Qiu, Yubin, Esterberg, Robert, Huang, Qian, Prasanna, Ganesh, Saint-Geniez, Magali, Aranda, Jorge and Bao, Yi (2024) Double-stranded RNA induces retinal pigment epithelium cell degeneration and inflammation. BioRxiv.

Kluge, Felix, Yonatan, Brand, Stefano, Bertuletti, Ilaria, D'Ascanio, Eran, Gazit, Tecla, Bonci, Cameron, Kirk, Arne, Küderle, Encarna, Micó Amigo, Luca, Palmerini, Anisoara, Paraschiv-Ionescu, Francesca, Salis, Abolfazi, Soltani, Martin, Ullrich, Lisa, Alcock, Kamiar, Aminian, Clemens, Becker, Philip, Brown, Joren, Buekers, Anne-Elie, Carsin, Marco, Caruso, Brian, Caulfield, Andrea, Cereatti, Lorenzo, Chiari, Carlos, Echevarria, Bjoern M, Eskofier, Jordi, Evers, Judith, Garcia-Aymerich, Hache, Tilo, Clint, Hansen, Jeffrey M., Hausdorff, Hugo, Hiden, Emily, Hume, Alison, Keogh, Sarah, Koch, Walter, Maetzler, Dimitrios, Megaritis, Martijn, Niessen, Or, Perlman, Lars, Schwickert, Kirsty, Scott, Basil, Sharrack, Henrik, Sillén, David, Singleton, Beatrix, Vereijken, Ioannis, Vogiatzis, Alison, J. Yarnall, Lynn, Rochester, Claudia, Mazzà, Silvia, Del Din and Mueller, Arne (2024) Real-World Gait Detection Using a Wrist-Worn Inertial Sensor: Validation Study. JMIR formative research, 8. e50035. ISSN 2561-326X

Knez, Benjamin (2024) Viscosity reduction and stabilization of highly concentrated monoclonal antibody solutions with proline analogues. International journal of pharmaceutics. ISSN 03785173

Korencic, Anja (2024) Position Statement in Support of Cell Bank Stability Monitoring from a Single Storage Location of Equivalent Storage Condition. BioPhorum.

Kotoni, Dorina, Zelesky, Todd, Huang, Zongyon, Baertschi, Steve, Adams, Neal, Marden, Stacey, Campbell, John, Foti, Chris, Laue, Christian, Marillier, Pascal, Ultramari, Maria, Ribeira Franca, Jucara, Van Cleempoel, An, Santos, Ana Claudia, Wang, Chloe, Meng, Liping and Hicks, Simon (2024) Peak Purity Assessments in Forced Degradation Studies - an Industry Perspective. LC-GC europe : Solutions for Separation Scientists., 1 (1). pp. 22-31.

Krajnc, Aleksander, Lin, Yu-Hsien, Moeller, Jens Reinhold, Reisinger, Veronika Bettina, Vasl, Jozica and Krajnc, Aleksander (2024) Identification of Acyl-Protein Thioesterase-1 as a Polysorbate-Degrading Host Cell Protein in a Monoclonal Antibody Formulation Using Activity-Based Protein Profiling. Journal of pharmaceutical sciences. ISSN 00223549

Krishnan, Michelle (2024) People of TM: Video of Michelle Krishnan. Linked-In.

Kulma, Magdalena, Šakanović, Aleksandra, Bedina-Zavec, Apolonija, Caserman, Simon, Omersa, Neža, Šolinc, Gašper, Orehek, Sara, Hafner-Bratkovič, Iva, Kuhar, Urška, Slavec, Brigita, Krapež, Uroš, Ocepek, Matjaž, Kobayashi, Toshihide, Kwiatkowska, Katarzyna, Jerala, Roman, Podobnik, Marjetka and Anderluh, Gregor (2024) Sequestration of membrane cholesterol by cholesterol-binding proteins inhibits SARS-CoV-2 entry into Vero E6 cells. Biochemical and Biophysical Research Communications, 716. ISSN 0006291X

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Lemmens, Myriam, Dorsheimer, Lena, Dietz-Baum, Yasmin and Zeller, Andreas (2024) Non-clinical safety assessment of novel drug modalities: Genome safety perspectives on viral-, nuclease- and nucleotide-based gene therapies. Mutation research. Genetic toxicology and environmental mutagenesis, 896. p. 503767. ISSN 1879-3592

Li, Wei and Leclair, Alexandre (2024) Green Chemistry Articles of Interest to the Pharmaceutical Industry. Organic Process Research & Development, 28 (3). pp. 652-660. ISSN 1083-61601520-586X

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