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Auld, Douglas and Nettleton, David (2024) Tight-binding small molecule carboxylesterase 2 inhibitors reduce intracellular Irinotecan activation. Journal of medicinal chemistry. ISSN 1520-4804; 0022-2623

Axelsson, GT, Loureiro, Joe, Orth, Anthony, Jennings, Lori and Gudnason, Vilmundur (2024) Proteomic associations with forced expiratory volume – a Mendelian randomisation study. Respiratory Research.

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Bernier, Jacques, Magnin, Isabelle, le Gallic de Kerizouët, Esthelle, Kenfak, Alain, Boschung, Jacques and Rebhan, Michael (2024) Revolutionizing Health Care Management: The 8Ps Value Proposition. Harvard business review : HBR.

Bitterlich, Andre, Mihorko, Andrej and Juhnke, Michael (2024) Design Space and Control Strategy for the Manufacturing of Wet Media Milled Drug Nanocrystal Suspension by Adopting Mechanistic Process Modeling. Pharmaceutics, 16 (3). p. 328. ISSN 1999-4923

Bluemel, Markus, Pohl, Thomas, Cordoba-Rodriguez, Ruth, Carroll, James, Beardsley, Richard, Maggio, Frank, Wylie, David, Tsang, Valerie, Ehrick, Robin, Francq, Bernard, Taktak, Sonia, Spasoff, Andy, Morrison, Amy, Albarghouti, Methal and Zhimei, Du (2024) Patient-centric Comparability Assessment of Biopharmaceuticals. Journal of pharmaceutical sciences.

Bornkamp, Bjoern, Zaoli, Silvia, Azzarito, Michela, Martin, Ruvie, Müller, Carsten Philipp, Moloney, Conor, Giulia, Capestro and Ohlssen, David (2024) Predicting subgroup treatment effects for a new study: Motivations, results and learnings from running a data challenge in a pharmaceutical corporation. Pharmaceutical statistics. ISSN 1539-1612

Brocklehurst, Cara, Altmann, Eva, Andre, Jerome, Bon, Corentin, Caya, Thomas, Davis, Holly, Decoret, Odile, Dunstan, David, Ertl, Peter, Ginsburg-Moraff, Carol, Grob, Jonathan, Gosling, Daniel, Lapointe, Guillaume, Majumdar, Dyuti, Marziale, Alexander, Mues, Heinrich, Palmieri, Marco, Racine, Sophie, Robinson, Richard, Springer, Clayton, Tan, Kian, Ulmer, William, West, Laura and Wyler, Rene (2024) MicroCycle: An Integrated and Automated Platform to Accelerate Drug Discovery. Journal of medicinal chemistry, 67 (3). pp. 2118-2128. ISSN 1520-4804

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Chen, Hao, King, Frederick, Zhou, Bin, Wang, Yu, Canedy, Carter, Hayashi, Joel, Zhong, Yang, Chang, Max, Pache, Lars, Wong, Julian, Jia, Yong, Joslin, John, Jiang, Tao, Benner, Christopher, Chanda, Sumit and Zhou, Yingyao (2024) Drug target prediction through deep learning functional representation of gene signatures. Nature communications, 15 (1). p. 1853. ISSN 2041-1723

Cuyckens, Filip, Hvenegaard, Mette G, Cassidy, Kenneth C, Spracklin, Douglas K, James, Alexander David, Pederson, Mette L, Scarfe, Graeme, Wagner, David S, Georgi, Katrin, Schieferstein, Hanno, Bjornsdottir, Inga, Romeo, Andrea A, Da-violante, Georges, Blech, Stefan, Hoffman, Matthew, Schulz, Simone, Moliner, Patricia and Young, Graeme C (2024) Recommendations on the Use of Multiple Labels in Human Mass Balance Studies. Drug metabolism and disposition: the biological fate of chemicals, 52 (3). pp. 153-158. ISSN 1521-009X

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Daniel, Puckhaber, Jan Henrik, Finke, David, Sarah, Gururajan, Bindhu, Rane, Supriya and Arno, Kwade (2024) Effect of particle size on the dispersion behavior of magnesium stearate blended with microcrystalline cellulose. International journal of pharmaceutics. p. 123792. ISSN 1873-3476

Dhareshwar, Sundeep, Matharu, Amol and Cao, Yu(Jade) (2024) Identifying chemical stabilizers - presenting a case study using a rapid 3-day accelerated excipient screening methodology. AAPS PharmSciTech, 12 (25). ISSN 1530-9932

Dittrich, Birger, Connor, Lauren, Fabbiani, Francesca and Piechon, Philippe (2024) Linking solid-state phenomena via energy differences in `archetype crystal structures'. IUCrJ. ISSN 2052-2525

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Elbatsh, Ahmed, Maira, Michel and Manchado Robles, Eusebio (2024) INPP5A phosphatase is a synthetic lethal target in GNAQ and GNA11-mutant melanomas. Nature cancer. ISSN 2662-1347

Ertl, Peter (2024) Database of 4 Million Medicinal Chemistry-Relevant Ring Systems. Journal of chemical information and modeling, 64 (4). pp. 1245-1250. ISSN 1549-960X

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Fluetsch, Andrin, Di Lascio, Elena, Gerebtzoff, Gregori and Rodriguez Perez, Raquel (2024) Adapting Deep Learning QSPR Models to Specific Drug Discovery Projects. Molecular Pharmaceutics. ISSN 1543-83841543-8392

Fluetsch, Andrin, Trunzer, Markus, Gerebtzoff, Gregori and Rodriguez Perez, Raquel (2024) Deep Learning Models Compared to Experimental Variability for the Prediction of CYP3A4 Time-Dependent Inhibition. Chemical research in toxicology, 37 (4). pp. 549-560. ISSN 1520-5010

Fluetsch, Andrin, Trunzer, Markus, Gerebtzoff, Gregori and Rodriguez Perez, Raquel (2024) Deep Learning Models Compared to Experimental Variability for the Prediction of CYP3A4 Time-Dependent Inhibition. Chemical research in toxicology, 37 (4). pp. 549-560. ISSN 1520-5010

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Gallou, Fabrice (2024) Scalability of Pharmaceutical Formation by Mechanochemistry in batch. ChemSusChem. e202301220.

Gellermann, Gerald, Kirsch, Stephan and den Engelsman, John (2024) Fine-tuning Analytical Development Strategies For Every Phase. Bioprocess Online.

Godinez Navarro, William, Trifonov, Vladimir, Fang, Bin, Kuzu, Guray, Pei, Amy, Guiguemde, Armand, Martin, Eric, King, Frederick, Jenkins, Jeremy and Skewes-Cox, Peter (2024) Compound activity prediction with dose-dependent transcriptomic profiles and deep learning. Journal of Chemical Information and Modeling. ISSN 1549-95961549-960X

Grevot, Armelle, Boisclair, Julie, Irizarry, Armando, Guffroy, Magali, Hall, Peter, Pohlmeyer-Esch, Gabriele, Jacobsen, Matt, Bach, Ute, Frisk, Ana Lena, Dybdal, Noel and Palazzi, Xavier (2024) Use of virtual control groups in nonclinical toxicity studies: the anatomic pathology perspective. Experimental and Toxicologic Pathology. ISSN 0192-62331533-1601

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Heuser, Alisa, Abdul Rahman, Wassim, Bechter, Elisabeth, Blank, Jutta, Buhr, Sylvia, Fontana, Patrizia, Meyerhofer, Marco, Strang, Ross, Schrapp, Maxime, Zimmermann, Catherine, Cortes-Cros, Marta, Moebitz, Henrik, Hamon, Jacques, Mermet-Meillon, Fanny and Erdmann, Dirk (2024) Challenges for the Discovery of Non-Covalent WRN Helicase Inhibitors. ChemMedChem.

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Iyer, Ganesh, Darpo, Borje, Xue, Hongqi, Lecot, Jean, Zack, Julia, Bebrevska, Lidiya, Weis, Wendy and Drollmann, Anton Franz (2024) Concentration-QTcF modeling of Icenticaftor from a randomized, placebo- and positive-controlled thorough QT (TQT) study in healthy participants. Journal of cystic fibrosis :. pp. 1-13. ISSN 2160-763X

Izem, Rima, Zuber, Emmanuel, Daizadeh, Nadia, Bretz, Frank, Sverdlov, Alex, Edrich, Pascal, Branson, Janice, Degtyarev, Evgeny, Sfikas, Nikolaos and Hemmings, Robert (2024) Decentralized clinical trials: scientific considerations through the lens of the estimand framework. Therapeutic Innovation and Regulatory Science.

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Ji, Yan and Sy, Sherwin (2024) Utility and impact of quantitative pharmacology on dose selection and clinical development of immuno-oncology therapy. Acta Pharmaceutica Sinica B.

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Keenan, Charlotte, Al-Haddawi, Muthafar, Bienvenu, Jean-Guy, Bradley, Alys, Brown, Paul, Chen, Hepei, Colman, Karyn, Elwell, Michael, Gatto, Nicholas, Goodman, Dawn, Jacob, Binod, Lanning, Lynda, McKinney, LuAnn, Muhlbrad, Erin, Perry, Rick, Piaia, Alessandro, Potenta, Daniel Lee, Regan, Karen, Sefing, Benjamin, Woicke, Jochen and Zwick, Craig M (2024) Guide for Combining Primary Tumors for Statistical Analysis in Rodent Carcinogenicity Studies. Toxicologic pathology. p. 1926233241230553. ISSN 1533-1601

Khera, Eshita (2024) People of TM: Videos of Eshita Khera. LinkedIn.

Klokman, Garrett, Xu, YongYao, Bond, Kyle, Wu, Xiaoqiu, Schustak, Joshua, Mandelbaum, Jorgi, Twarog, Michael, Han, Hongwei, Paulina, Mary-Kate, Coble, Matthew, Hayden, Chris, Galarneau, Jean-Rene, Demirs, John, Qiu, Yubin, Esterberg, Robert, Huang, Qian, Prasanna, Ganesh, Saint-Geniez, Magali, Aranda, Jorge and Bao, Yi (2024) Double-stranded RNA induces retinal pigment epithelium cell degeneration and inflammation. BioRxiv.

Knez, Benjamin (2024) Viscosity reduction and stabilization of highly concentrated monoclonal antibody solutions with proline analogues. International journal of pharmaceutics. ISSN 03785173

Kotoni, Dorina, Zelesky, Todd, Huang, Zongyon, Baertschi, Steve, Adams, Neal, Marden, Stacey, Campbell, John, Foti, Chris, Laue, Christian, Marillier, Pascal, Ultramari, Maria, Ribeira Franca, Jucara, Van Cleempoel, An, Santos, Ana Claudia, Wang, Chloe, Meng, Liping and Hicks, Simon (2024) Peak Purity Assessments in Forced Degradation Studies - an Industry Perspective. LC-GC europe : Solutions for Separation Scientists., 1 (1). pp. 22-31.

Krishnan, Michelle (2024) People of TM: Video of Michelle Krishnan. Linked-In.

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Leane, Michael, Pitt, Kendal, Reynolds, Gavin, Andersen, Sune, Bartsch, Jens, Carlin, Brian, Crean, Abina, Gamble, John, Gururajan, Bindhu, Khimyak, Yaroslav, Kleinebudde, Peter, Koynov, Sara, Kuentz, Martin, Misic, Zdravka, Moreton, Chris, Peter, Stefanie, Sheehan, Stephen, Stone, Elaine, Suzuki, Hirofumi, Tantuccio, Anthony and Van Snick, Bernd (2024) Ten Years of the Manufacturing Classification System: A review of literature applications and an extension of the framework to continuous manufacture. Pharmaceutical Development and Technology. pp. 1-45. ISSN 1083-74501097-9867

Liu, Xiaojuan, Gerszten, Robert E, Jennings, Lori, Gudnason, Vilmundur, Sanders, Jason L and Odden, Michelle C (2024) Plasma proteomic signature of human longevity. Aging cell. e14136. ISSN 1474-9726

Loureiro, Joe, Jennings, Lori, Aspesi Jr, PJ, Mapa, Felipa, Perry, Darryl, Parker, Jefferson, Williams, Blake, Su, Wendy, Tabacman, Eduardo, Delisle, Kirk, Avishan, Kayvan, Williams, Alan, Myers, Vic and Janjic, Nebojsa (2024) Modeling Proteomes Using Unsupervised Machine Learning Approaches on SomaScan Aptamer-based Proteome Hybridization Technology. bioRxiv.

Luescher, Michael and Gallou, Fabrice (2024) Interactions of multiple metrics and environmental indicators to assess processes, detect environmental hotspots, and guide future development. Green chemistry.

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Mann, Greg and Allmendinger, Simon (2024) Asymmetric Synthesis of α-Chloroamides via Photoenzymatic Hydroalkylation of Olefins. Journal of the American Chemical Society. ISSN 1520-5126

Maremanda, Vishnu Datta, Maertin, Dirk, Bitar, Malak and Pandey, Abhijeet (2024) Wurster Technology-Assisted Step-by-Step Engineering of Multi-layered Pellets (Sprinkles): Microscopy, Micro-CT, and e-Tongue-Based Analysis. AAPS PharmSciTech, 25 (3). p. 50. ISSN 1530-9932

McTeer, Matthew, Applegate, Douglas and Mesenbrink, Peter (2024) Machine learning approaches to enhance diagnosis and staging of patients with MASLD using routinely available clinical information. PLoS ONE, 19 (2). e0299487. ISSN 1932-6203

Mermet-Meillon, Fanny Anne-Marie, Mercan, Samuele, Allard, Cyril, Bleu, Melusine, Calkins, Keith, Bauer-Probst, Beatrice, Knehr, Judith, Altorfer, Marc, Naumann, Ulrike, Sprouffske, Kathleen, Barys, Louise, Sesterhenn, Fabian and Galli, Giorgio (2024) Protein destabilization underlies pathogenic missense mutations in ARID1B. Nature structural & molecular biology. ISSN 1545-9985

Mesenbrink, Peter and Hernandez Penna Straube, Sabina (2024) Regulatory Issues of Platform Trials: Learnings from EU-PEARL. Clinical pharmacology and therapeutics. ISSN 1532-6535

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Moresis, Anastasios, Restivo, Leonardo, Bromilow, Sophie, Flik, Gunnar, Rosati, Giorgio, Scorrano, Fabrizio, Tsoory, Michael, O'Connor, Eoin C., Gaburro, Stefano and Bannach-Brown, Alexandra (2024) A minimal metadata set (MNMS) to repurpose non-clinical in vivo data for biomedical research. Lab animal. ISSN 1548-4475; 0093-7355

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Nunes, Jairo, Dubost, Valerie, Wuersch, Kuno, Penraat, Kelley and Balavenkatraman, Kamal Kumar (2024) De-risking ASO-induced histopathology in spinal cord of monkeys by molecular localization investigations. Toxicologic pathology.

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Pan, Rongqing, Wang, Youzhen, Qiu, Shumei, Villalobos-Ortiz, Mariana, Ryan, Jeremy, Erick, Morris, Halilovic, Ensar and Letai, Anthony (2024) BH3 profiling as pharmacodynamic biomarker for the activity of BH3 mimetics. Haematologica, 109 (4). pp. 1253-1258. ISSN 1592-8721

Panikulam, Sherin, Lebesgue, Nicolas, Villiger, Thomas K., Anderka, Oliver, Kroener, Frieder, Hanke, Alexander and Karle, Anette (2024) Host cell protein networks as a novel co-elution mechanism during protein A chromatography. Biotechnology and bioengineering, 121 (5). pp. 1716-1728. ISSN 1097-0290

Plummer, Scott and Gallou, Fabrice (2024) Buchwald-Hartwig Aminations of Aryl Halides Using Nitroaromatics as Coupling Partners: Overcoming Hydrodehalogenation Pathway in Water. ACS Catalysis, 14. pp. 4099-4107.

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Rodon, Jordi, Demanse, David, Rugo, Hope S., Burris, Howard A., Simo, Rafael, Farooki, Aziz, Wellons, Melissa F., André, Fabrice, Hu, Huilin, Vuina, Dragica, Quadt, Cornelia and Juric, Dejan (2024) A risk analysis of alpelisib-induced hyperglycemia in patients with advanced solid tumors and breast cancer. Breast cancer research. ISSN 1465-542X

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Saldivia Concepcion, Manuel Alejandro, C A Lima, Ana Paula and Mottram, Jeremy (2024) A promising pipeline of preclinical drug candidates for leishmaniasis and chronic Chagas disease. Trends in parasitology, 40 (3). pp. 211-213. ISSN 14714922

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Saxer, Franziska, Demanse, David, Brett, Alan, Laurent, Didier, Mindeholm, Linda, Philip, Conaghan and Schieker, Matthias (2024) Prognostic value of B-score for predicting joint replacement in the context of osteoarthritis phenotypes: Data from the osteoarthritis initiative. Osteoarthritis and Cartilage Open.

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Thoma, Gebhard, Miltz, Wolfgang, Srinivas, Honnappa, Penno, Carlos, Kiffe, Michael, Gajewska, Monika, Klein, Kai, Evans, Amanda, Beerli, Christian and Roehn, Till (2024) Structure Guided Elaboration of a Fragment-Like Hit into an Orally Efficacious Leukotriene A4 Hydrolase Inhibitor. Journal of medicinal chemistry.

Tosco, Paolo (2024) A stub a day keeps the docstrings at bay. RDKit blog.

Trunzer, Markus, Teigao, Joana, Huth, Felix, Poller, Birk, Rodriguez Perez, Raquel, Desrayaud, Sandrine and Faller, Bernard (2024) Improving In Vitro-In Vivo Extrapolation of Clearance Using Rat Liver Microsomes for Highly Plasma Protein-Bound Molecules. Drug metabolism and disposition: the biological fate of chemicals, 52 (5). pp. 345-354. ISSN 1521-009X

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Vach, Werner and Saxer, Franziska (2024) Anchor-based minimal important difference values are often sensitive to the distribution of the change score. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. ISSN 1573-2649

Velcicky, Juraj, Janser, Philipp, Gommermann, Nina, Brenneisen, Silke, Ilic, Slavica, Vangrevelinghe, Eric, Stiefl, Nikolaus, Boettcher, Andreas, Malinverni, Claire, Dawson, Janet, Desrayaud, Sandrine, Beltz, Karen, Hinniger, Alexandra, Dekker, Carien, Farady, Christopher and Mackay, Angela (2024) Discovery of Potent, Orally Bioavailable, Tricyclic NLRP3 Inhibitors. Journal of medicinal chemistry. ISSN 1520-4804

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Vostiarova, Helena and Engelhardt, Volker (2024) EBF project: promoting replacement of preclinical matrix for IGM assays. not known at this stage.

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Xie, Xiao, Moon, Patrick J., Crossley, Steven W. M., Elledge, Susanna K., Bischoff, Amanda J., Reeves, Audrey G., Gonzalez-Valero, Angel, He, Dan, Dao, Nam, Li, Gen, McKenna, Jeffrey, Wells, James A., Toste, F. Dean and Chang, Christopher J. (2024) Oxidative cyclization reagents reveal tryptophan cation-π interactions. Nature. ISSN 1476-4687

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