Homodimeric alkaline phosphatase located at Helicoverpa armigera midgut, a putative receptor of Cry1Ac contains -GalNAc in terminal glycan structure as interactive epitope.
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Sarkar, Anindya, Hess, Daniel, Mondal, Hossain A, Banerjee, Santanu, Sharma, Hari C and Das, Sampa (2009) Homodimeric alkaline phosphatase located at Helicoverpa armigera midgut, a putative receptor of Cry1Ac contains -GalNAc in terminal glycan structure as interactive epitope. Journal of Proteome Research, 8 (4). pp. 1838-1848. ISSN 1535-3893
Abstract
Helicoverpa armigera causes massive yield loss of various crops globally. Bacillus thuringiensis coded Cry1Ac toxin is effective against the pest. Through the present investigation an alkaline phosphatase type putative receptor of the toxin was identified in the target insect gut BBMV. Lectin-ligand immunoblot assay detected the presence of alpha-GalNAc residue at the non reducing terminal of the glycan structure in the membrane bound HaALP protein which mediates the toxin-receptor interaction.
| Item Type: | Article |
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| Additional Information: | archiving not formally supported by this publisher |
| Keywords: | Alkaline phosphatase; Cry1Ac; Helicoverpa armigera; Putative receptor; Toxin receptor interaction |
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| Date Deposited: | 14 Dec 2009 13:50 |
| Last Modified: | 31 Jan 2013 01:02 |
| URI: | https://oak.novartis.com/id/eprint/964 |