Baltus, Christine, Press, Neil, Antonijevic, Milan, Tizzard, Graham, Coles, Simon and Spencer, John (2012) Synthesis of a biphenyl library for studies of hydrogen bonding in the solid state. Tetrahedron, 68 (45). pp. 9272-9277. ISSN 0040-4020

Abstract

A biphenyl library incorporating amide and sulfonamide groups has been synthesised via microwave-mediated Suzuki-Miyaura couplings. Many derivatives were crystallised from dichloromethane/methanol and analysed by single crystal X-ray diffraction. An interesting structure was obtained for N-(4'-methylbiphenyl-4-yl)acetamide with Z'=6 and hydrogen-bonding networks of the type N–H…O in the unit cell.

Item Type:	Article
Related URLs:	http://dx.doi.org/10.1016/j.tet.2012.08....
Additional Information:	CASE collaboration
Keywords:	Cross coupling, microwaves, biphenyl amides, hydrogen bonds, Z', X-ray crystallography.
Related URLs:	http://dx.doi.org/10.1016/j.tet.2012.08....
Date Deposited:	13 Oct 2015 13:14
Last Modified:	13 Oct 2015 13:14
URI:	https://oak.novartis.com/id/eprint/7015