Mainolfi, Nello, Zhang, Yun and Patel, Sejal (2012) Copper-Catalyzed Decarboxylative C—N Cross-Coupling for N-Arylation. Chemical Science, on lin. ISSN 2041-6520

Abstract

A novel approach for N-arylation utilizing aryl carboxylic acids as stable, inexpensive and widely available arylating reagents was developed. Employing a simple copper(II)-phenanthroline catalyst system, several benzoic acids bearing suitable ortho-substitutions undergo decarboxylative C—N cross-coupling effectively with various N-nucleophiles.

Item Type:	Article
Additional Information:	author can archive post-print (ie final draft post-refereeing); Author's version in web repository after 12 months or immediately with fee
Date Deposited:	13 Oct 2015 13:14
Last Modified:	13 Oct 2015 13:14
URI:	https://oak.novartis.com/id/eprint/6936