In vitro blood distribution and plasma protein binding of the tyrosine kinase inhibitor imatinib and its active metabolite, CGP74588, in rat, mouse, dog, monkey, healthy humans and patients with acute lymphatic leukaemia.
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Kretz, Olivier, Weiss, Markus, Schumacher, Martin and Gross, Gerhard (2004) In vitro blood distribution and plasma protein binding of the tyrosine kinase inhibitor imatinib and its active metabolite, CGP74588, in rat, mouse, dog, monkey, healthy humans and patients with acute lymphatic leukaemia. British journal of clinical pharmacology, 58 (2). pp. 212-216. ISSN 0306-5251
Official URL: http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retri...
Abstract
To determine blood binding parameters of imatinib and its metabolite CGP74588 in humans and non-human species.
| Item Type: | Article |
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| Date Deposited: | 31 Jan 2012 00:45 |
| Last Modified: | 01 Feb 2013 00:46 |
| URI: | https://oak.novartis.com/id/eprint/6096 |