Voirol, M, Stalder, G A, Fasel, J, Sechaud, Romain, Desbaillets, L G, Kapp, F, Krieg, P, Aenishänslin, H W and Wyss, G (1983) [Multicenter study on the litholytic effect of ursodeoxycholic acid. 30 cases]. Schweizerische medizinische Wochenschrift, 113 (17). pp. 643-645. ISSN 0036-7672

Abstract

In the context of a cooperative clinical trial carried out in the Cantons of Basel and Vaud, Switzerland, the litholytic effect of ursodeoxycholic acid (Ursochol) in a daily dose of 9 mg/kg was investigated in 42 patients with radiotransparent gallstones. The litholytic effect was evident in 22 (73%) of the 30 patients followed up for a maximum period of 1 year. Complete dissolution of gallstones was obtained in 40% of cases. In addition, ursodeoxycholic acid significantly reduced (p less than 0,001) the dyspeptic-painful symptoms and the number of biliary colics. Tolerance was excellent. In particular, no cases of diarrhea were observed.

Item Type:	Article
Date Deposited:	28 Jan 2012 00:45
Last Modified:	01 Feb 2013 00:46
URI:	https://oak.novartis.com/id/eprint/5615