Blank, Jarred, Kaegi, Andreas and Spaeti, Markus (2026) Implementation of Large-Scale Multi-Reactor Automation for Process Development. Helvetica Chimica Acta, 109 (3). pp. 1-9. ISSN 1522-2675

Abstract

Pharmaceuticals increasing complexity requires longer synthesis with unique processes for each step, increasing the number of experiments to develop robust sustainable processes. The time to develop these processes are getting shorter and automation can support the growing need to efficiently perform more experiments. Automation reaction screening focuses more on small scale High Throughput Experimentation (HTE) which may not be applicable for late phase process development. To support these activities and decrease development time, we describe the implementation of a flexible large-scale multi reactor automation platform for process development.

Item Type:	Article
Date Deposited:	28 Mar 2026 00:45
Last Modified:	28 Mar 2026 00:45
URI:	https://oak.novartis.com/id/eprint/56125