Nisbet-Brown, Eric, Olivieri, Nancy F, Giardina, Patricia J, Grady, Robert W, Neufeld, Ellis J, Sechaud, Romain, Krebs-Brown, Axel, Anderson, Judith, Alberti, Daniele Maria, Sizer, Kurt and Nathan, David G (2003) Effectiveness and safety of ICL670 in iron-loaded patients with thalassaemia: a randomised, double-blind, placebo-controlled, dose-escalation trial. Lancet, 361 (9369). pp. 1597-1602. ISSN 0140-6736

Abstract

Transfusional iron overload is a potentially fatal complication of the treatment of thalassaemia. We aimed to investigate short-term efficacy, pharmacokinetic/pharma- codynamic (PK/PD) relations, and safety of ICL670, a novel, tridentate, orally active iron chelator.

Item Type:	Article
Related URLs:	http://www.ncbi.nlm.nih.gov/sites/entrez...
Related URLs:	http://www.ncbi.nlm.nih.gov/sites/entrez...
Date Deposited:	28 Jan 2012 00:45
Last Modified:	01 Feb 2013 00:46
URI:	https://oak.novartis.com/id/eprint/5608