Deferasirox does not induce QT/QTc-prolongation in healthy subjects.
Tools
Sechaud, Romain, Dumortier, Thomas and Balez, Sebastien (2009) Deferasirox does not induce QT/QTc-prolongation in healthy subjects. International journal of clinical pharmacology and therapeutics, 47 (5). pp. 321-327. ISSN 0946-1965
Official URL: http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retri...
Abstract
The International Conference on Harmonization (ICH) E14 guidance recommends that almost all drugs should undergo careful clinical testing in a thorough QT/QTc study. Deferasirox (Exjade, ICL670) is a once-daily oral iron chelator, developed for the treatment of blood transfusion-related iron overload.
Item Type: | Article |
---|---|
Date Deposited: | 28 Jan 2012 00:45 |
Last Modified: | 01 Feb 2013 00:46 |
URI: | https://oak.novartis.com/id/eprint/5502 |