The effect of food consumption on lumefantrine bioavailability in African children receiving artemether-lumefantrine crushed or dispersible tablets (Coartem) for acute uncomplicated Plasmodium falciparum malaria.
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Borrmann, Steffen, Sallas, William, Machevo, Sonia, González, Raquel, Björkman, Anders, Mårtensson, Andreas, Hamel, Mary, Juma, Elizabeth, Peshu, Judy, Ogutu, Bernhards, Djimdé, Abdoulaye, D'Alessandro, Umberto, Marrast, Anne Claire, Lefevre, Gilbert and Kern, Steven (2010) The effect of food consumption on lumefantrine bioavailability in African children receiving artemether-lumefantrine crushed or dispersible tablets (Coartem) for acute uncomplicated Plasmodium falciparum malaria. Tropical medicine & international health : TM & IH, 15 (4). pp. 434-441. ISSN 1365-3156
Abstract
Artemether-lumefantrine (AL) is first-line treatment for uncomplicated malaria in many African countries. Concomitant food consumption may affect absorption of lumefantrine but data in the most important target population, i.e. children, are lacking. Therefore, we evaluated the effect of food intake on oral lumefantrine bioavailability in African children with malaria.
| Item Type: | Article |
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| Date Deposited: | 28 Jan 2012 00:45 |
| Last Modified: | 01 Feb 2013 00:47 |
| URI: | https://oak.novartis.com/id/eprint/5090 |