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Micelle enabled C(sp2)–C(sp3) cross-electrophile coupling in water via synergistic nickel and copper catalysis†

Zhao, Kangming, Ge, Xiaobin, Zheng, Yu, Shen, Xiaodong, Shi, Lei, Gallou, Fabrice, Cortes-Clerget, Margery , Louis Regnier, Morgan , Parmentier, Michael, Ye, Ning and Wu, Bin (2021) Micelle enabled C(sp2)–C(sp3) cross-electrophile coupling in water via synergistic nickel and copper catalysis†. Chemical Communications, 57 (62). pp. 7629-7632. ISSN 1359-73451364-548X

Abstract

A robust and sustainable C(sp2)-C(sp3) cross- electrophile coupling was developed via nickle/copper synergistic catalysis under micellar conditions. This protocol provided a general method to access alkylated arenes with good to excellent yields in very large scale.

Item Type: Article
Date Deposited: 05 Nov 2021 00:45
Last Modified: 05 Nov 2021 00:45
URI: https://oak.novartis.com/id/eprint/45052

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