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An efficient protocol for the solid-phase synthesis of malondiamides.

Vogtle, Markus and Marzinzik, Andreas (2005) An efficient protocol for the solid-phase synthesis of malondiamides. Molecules, 10 (12). pp. 1438-1445. ISSN 1420-3049

Abstract

A novel and straightforward solid-phase synthesis of malondiamides containing a free nitrogen has been developed. These intermediates, which can be directly obtained in good yield and purity, can be further derivatised. This approach can be used for the synthesis of large split-and-mix-libraries.

Item Type: Article
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Additional Information: Open Access; free final full text version available at publisher's official URL; author can archive post-print (ie final draft post-refereeing); Publisher's version/PDF may be used; Authors are encouraged to submit their published articles to institutional repositories
Keywords: Combinatorial chemistry – Solid-phase synthesis – Amides – Acylations – Peptides
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Date Deposited: 13 Oct 2015 13:17
Last Modified: 13 Oct 2015 13:17
URI: https://oak.novartis.com/id/eprint/346

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