Lima, Fabio, Sharma, Upendra, Grunenberg, Lars, Saha, Debasmita, Johannsen, Sandra, Sedelmeier, Joerg Mathias, Van der Eycken, Erik and Ley, Steven (2017) A Lewis Base Catalysis Approach for the Photoredox Activation of Boronic Acids and Esters. Angewandte Chemie. International edition.

Abstract

We report herein the use of a dual catalytic system comprising a Lewis base catalyst such as quinuclidin-3-ol or 4-dimethylaminopyridine combined with a photoredox catalyst to
generate carbon radicals from either boronic esters or boronic acids. This system enabled a wide range of alkyl boronic esters and aryl or alkyl boronic acids to react via radical addition with electron-deficient olefins to efficiently form C–C bonds in a redox neutral fashion.

Item Type:	Article
Date Deposited:	14 Nov 2017 00:45
Last Modified:	14 Nov 2017 00:45
URI:	https://oak.novartis.com/id/eprint/34239