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A metabolomic profile is associated with the risk of incident coronary heart disease.

Vaarhorst, Anika A M, Verhoeven, Aswin, Weller, Claudia M, Böhringer, Stefan, Göraler, Sibel, Meissner, Axel, Deelder, André M, Henneman, Peter, Gorgels, Anton P M, van den Brandt, Piet A, Schouten, Leo J, van Greevenbroek, Marleen M, Merry, Audrey H H, Verschuren, W M Monique, van den Maagdenberg, Arn M J M, van Dijk, Ko Willems, Isaacs, Aaron, Boomsma, Dorret, Oostra, Ben A, van Duijn, Cornelia M, Jukema, J Wouter, Boer, Jolanda M A, Feskens, Edith, Heijmans, Bastiaan T and Slagboom, P Eline (2014) A metabolomic profile is associated with the risk of incident coronary heart disease. American heart journal, 168 (1). 45-52.e7. ISSN 1097-6744; 0002-8703

Abstract

Metabolomics, defined as the comprehensive identification and quantification of low-molecular-weight metabolites to be found in a biological sample, has been put forward as a potential tool for classifying individuals according to their risk of coronary heart disease (CHD). Here, we investigated whether a single-point blood measurement of the metabolome is associated with and predictive for the risk of CHD.

Item Type: Article
Date Deposited: 11 Mar 2017 00:45
Last Modified: 11 Mar 2017 00:45
URI: https://oak.novartis.com/id/eprint/32435

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