Steger-Hartmann, Thomas and Pognan, Francois (2017) The eTOX Consortium: To Improve the Safety Assessment of New Drug Candidates. Pharmazeutische Medizin, 1. pp. 3-13. ISSN ISSN 2191-6039

Abstract

After their incorporation into human risk assessment, reports on preclinical animal studies in most cases get buried in the archives. The wealth of these data is hardly accessible. The European Innovative Medicines Initiative project eTOX ("electronic toxicity") over the last years designed and implemented a strategy for leveraging these preclinical data and sharing them across pharmaceutical companies and academic institutions. The shared toxicological data can now be used by the participating companies to perform early safety assessments of new drug candidates and new pharmacological targets. In addition, the data are used to build in silico predictive tools for specific toxicological endpoint.

Item Type:	Article
Date Deposited:	23 May 2017 00:45
Last Modified:	23 May 2017 00:45
URI:	https://oak.novartis.com/id/eprint/31898