Camenisch, Gian P. (2016) Drug disposition classification systems in discovery and development: A comparative review of the BDDCS, ECCS and ECCCS concepts. Pharmaceutical Research.

Abstract

BDDCS, ECCS and ECCCS are compound disposition classification concepts that aim to streamline, de-risk and speed-up drug development. Although all three systems have the same purpose and are based on classifying drugs into four categories, they have different backgrounds and contrast in their criteria. Here the details, differences and most important applications of the three systems are reviewed with particular emphasis of their (principally complementary) roles for drug discovery and development.

Item Type:	Article
Keywords:	BDDCS · ECCS · ECCCS · drug disposition classification · enzyme/transporter interplay
Date Deposited:	12 Jul 2016 23:45
Last Modified:	12 Jul 2016 23:45
URI:	https://oak.novartis.com/id/eprint/29132